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Bruce Wang, MD

Photo of Bruce Wang, MD
Title(s)Associate Professor, Medicine
SchoolSchool of Medicine
Phone415-476-6160
ORCID ORCID Icon0000-0003-3486-5494 Additional info
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    Collapse Biography 
    Collapse education and training
    Stanford UniversityBAS2000Biological Sciences and Philosophy
    University of California San FranciscoM.D.2007School of Medicine
    University of California San FranciscoResidency2009Department of Medicine
    University of California San FranciscoFellowship2011Division of Gastroenterology
    Stanford University / HHMIPostdoctoral Fellow2016Developmental Biology (Lab of Roel Nusse)
    Collapse awards and honors
    Burroughs Wellcome Fund2016Career Award for Medical Scientists
    UCSF School of Medicine2006Dean's Prize in Research

    Collapse Overview 
    Collapse overview
    My lab studies how the different cell types in the liver, in particular the hepatocyte, are generated during development, patterned and maintained during adulthood, and regenerate after injury. Our long-term goals are to improve the understanding of liver disease pathophysiology and develop novel methods of treatment for liver diseases, including cell replacement therapy. Currently, we have two major research focuses: 1) understanding the biology of adult hepatocyte stem cells and 2) developing a liver cell atlas. We take innovative and integrated approaches to address these two areas using the tools of stem cell biology, developmental biology, genomics and tissue engineering.

    I also study the porphyrias, a group of inherited diseases related to defects in heme synthesis pathway. I am a member of the Porphyrias Consortium, a NIH sponsored Rare Disease Clinical Research Consortium. The purpose of the network is to integrate translational studies of the porphyrias with clinical trials testing new therapeutics.

    Collapse Research 
    Collapse research activities and funding
    Mechanisms of Intercellular Heme Homeostasis in Liver
    NIH R01DK134783Apr 1, 2023 - Mar 31, 2027
    Role: Co-Investigator
    Characterizing zonated hepatocyte sexual dimorphism and its role in fatty liver disease
    NIH R01DK131227Feb 1, 2023 - Jan 31, 2028
    Role: Principal Investigator
    Single cell characterization and organoid development of pediatric hepatoblastoma
    DoD RA210018Oct 1, 2022
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Towards a reference cell atlas of liver diversity over the human lifespan. Nat Rev Gastroenterol Hepatol. 2025 Oct 13. Taylor SA, Bader GD, MacParland S, Mullen AC, Andrews T, Cuenca AG, DasGupta R, Gehring AJ, Grün D, Guilliams M, Gulamhusein A, Henderson NC, Hirschfield G, Huppert SS, Itzkovitz S, Jiang ZG, Lauer GM, McGilvray I, Mysore KR, Pirola CJ, Quon G, Rahbari M, Regev A, Ricciuto A, Scott CL, Sharma A, Sookoian S, Tana MM, Teichmann SA, Vallier L, Vlachos IS, Wang B, Zhen M. PMID: 41083606.
      View in: PubMed   Mentions:
    2. A molecular cell atlas of mouse lemur, an emerging model primate. Nature. 2025 Aug; 644(8075):173-184. Tabula Microcebus Consortium, Ezran C, Liu S, Chang S, Ming J, Botvinnik O, Penland L, Tarashansky A, de Morree A, Travaglini KJ, Zhao J, Wang G, Hasegawa K, Sin H, Sit R, Okamoto J, Sinha R, Zhang Y, Karanewsky CJ, Pendleton JL, Morri M, Perret M, Aujard F, Stryer L, Artandi S, Fuller MT, Weissman IL, Rando TA, Ferrell JE, Wang B, De Vlaminck I, Yang C, Casey KM, Albertelli MA, Pisco AO, Karkanias J, Neff N, Wu AR, Quake SR, Krasnow MA. PMID: 40739356; PMCID: PMC12328211.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    3. Mouse lemur cell atlas informs primate genes, physiology and disease. Nature. 2025 Aug; 644(8075):185-196. Ezran C, Liu S, Chang S, Ming J, Guethlein LA, Wang MFZ, Dehghannasiri R, Olivieri J, Frank HK, Tarashansky A, Koh W, Jing Q, Botvinnik O, Antony J, Tabula Microcebus Consortium, Pisco AO, Karkanias J, Yang C, Ferrell JE, Boyd SD, Parham P, Long JZ, Wang B, Salzman J, De Vlaminck I, Wu AR, Quake SR, Krasnow MA. PMID: 40739355; PMCID: PMC12328237.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    4. A Prospective, Blinded Study of Symptom Prevalence and Specificity of Porphyrin Precursors in Carriers of Acute Hepatic Porphyria. Liver Int. 2025 Jul; 45(7):e70156. Merati M, Jayakumar N, Kapoor Y, Naik H, Balwani M, Anderson KE, Bonkovsky HL, Desnick RJ, McGuire B, Phillips J, Bissell DM, Wang B. PMID: 40485347; PMCID: PMC12146827.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. PCSK9 drives sterol-dependent metastatic organ choice in pancreatic cancer. Nature. 2025 Jul; 643(8074):1381-1390. Rademaker G, Hernandez GA, Seo Y, Dahal S, Miller-Phillips L, Li AL, Peng XL, Luan C, Qiu L, Liegeois MA, Wang B, Wen KW, Kim GE, Collisson EA, Kruger SF, Boeck S, Ormanns S, Guenther M, Heinemann V, Haas M, Looney MR, Yeh JJ, Zoncu R, Perera RM. PMID: 40399683.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    6. Liver involvement in a large cohort of patients with erythropoietic protoporphyria or X-linked protoporphyria. Hepatol Commun. 2025 Mar 01; 9(3). Levy C, Naik H, Overbey J, Hedstrom K, Wang K, McDonough C, Freeman M, Keel SB, Erwin AL, Dickey AK, Leaf RK, Quigley J, Mazepa M, Wang B, Phillips J, Parker C, McGuire B, Kazamel M, Bonkovsky H, Rudnick S, Anderson KE, Moghe A, Thapar M, Saberi B, Wheeden K, Desnick R, Balwani M, Porphyrias Consortium of the Rare Diseases Clinical Research Network. PMID: 39969427; PMCID: PMC11841850.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    7. AAV capsid prioritization in normal and steatotic human livers maintained by machine perfusion. Nat Biotechnol. 2025 Jan 29. Kim JJ, Kurial SNT, Choksi PK, Nunez M, Lunow-Luke T, Bartel J, Driscoll J, Her CL, Dhillon S, Yue W, Murti A, Mao T, Ramos JN, Tiyaboonchai A, Grompe M, Mattis AN, Syed SM, Wang BM, Maher JJ, Roll GR, Willenbring H. PMID: 39881029; PMCID: PMC12304247.
      View in: PubMed   Mentions: 1     Fields:    
    8. Reducing diagnostic delays in acute hepatic porphyria using health records data and machine learning. J Am Med Inform Assoc. 2025 Jan 01; 32(1):63-70. Bhasuran B, Schmolly K, Kapoor Y, Jayakumar NL, Doan R, Amin J, Meninger S, Cheng N, Deering R, Anderson K, Beaven SW, Wang B, Rudrapatna VA. PMID: 38946554; PMCID: PMC11648717.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Long-term follow-up of givosiran treatment in patients with acute intermittent porphyria from a phase 1/2, 48-month open-label extension study. Orphanet J Rare Dis. 2024 Oct 03; 19(1):365. Sardh E, Balwani M, Rees DC, Anderson KE, Jia G, Sweetser MT, Wang B. PMID: 39363243; PMCID: PMC11448181.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    10. Perinatal liver inflammation is associated with persistent elevation of CXCL10 and its canonical receptor CXCR3 on common myeloid progenitors. bioRxiv. 2024 Aug 19. Alkhani A, Baskaran S, Murti A, Rapp B, Levy CS, Wang B, Nijagal A. PMID: 39229070; PMCID: PMC11370417.
      View in: PubMed   Mentions:
    11. An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome. Nat Commun. 2024 Mar 11; 15(1):2188. Liu S, Ezran C, Wang MFZ, Li Z, Awayan K, Tabula Microcebus Consortium, Long JZ, De Vlaminck I, Wang S, Epelbaum J, Kuo CS, Terrien J, Krasnow MA, Ferrell JE. PMID: 38467625; PMCID: PMC10928088.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    12. Liver transplantation and primary liver cancer in porphyria. Liver Int. 2025 Mar; 45(3):e15894. Lissing M, Wang B, Wahlin S. PMID: 38456621; PMCID: PMC11815609.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    13. Single-nuclei characterization of pervasive transcriptional signatures across organs in response to COVID-19. Elife. 2023 10 13; 12. COVID Tissue Atlas Consortium, Granados AA, Bucher S, Song H, Agrawal A, Chen AT, Peng T, Neff N, Pisco AO, Huang F, Wang B. PMID: 37830426; PMCID: PMC10575628.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    14. Reducing diagnostic delays in Acute Hepatic Porphyria using electronic health records data and machine learning: a multicenter development and validation study. medRxiv. 2023 Aug 31. Bhasuran B, Schmolly K, Kapoor Y, Jayakumar NL, Doan R, Amin J, Meninger S, Cheng N, Deering R, Anderson K, Beaven SW, Wang B, Rudrapatna VA. PMID: 37693437; PMCID: PMC10491361.
      View in: PubMed   Mentions:
    15. Evidence-based consensus guidelines for the diagnosis and management of protoporphyria-related liver dysfunction in erythropoietic protoporphyria and X-linked protoporphyria. Hepatology. 2024 03 01; 79(3):731-743. Levy C, Dickey AK, Wang B, Thapar M, Naik H, Keel SB, Saberi B, Beaven SW, Rudnick SR, Elmariah SB, Erwin AL, Goddu RJ, Hedstrom K, Leaf RK, Kazamel M, Mazepa M, Philpotts LL, Quigley J, Raef H, Ungar J, Anderson KE, Balwani M, Porphyrias Consortium of the Rare Diseases Clinical Network. PMID: 37505211; PMCID: PMC10818013.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    16. AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review. Gastroenterology. 2023 03; 164(3):484-491. Wang B, Bonkovsky HL, Lim JK, Balwani M. PMID: 36642627; PMCID: PMC10335308.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    17. Concordance of MERFISH spatial transcriptomics with bulk and single-cell RNA sequencing. Life Sci Alliance. 2023 01; 6(1). Liu J, Tran V, Vemuri VNP, Byrne A, Borja M, Kim YJ, Agarwal S, Wang R, Awayan K, Murti A, Taychameekiatchai A, Wang B, Emanuel G, He J, Haliburton J, Oliveira Pisco A, Neff NF. PMID: 36526371; PMCID: PMC9760489.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    18. A pilot study of oral iron therapy in erythropoietic protoporphyria and X-linked protoporphyria. Mol Genet Metab Rep. 2022 Dec; 33:100939. Balwani M, Naik H, Overbey JR, Bonkovsky HL, Bissell DM, Wang B, Phillips JD, Desnick RJ, Anderson KE. PMID: 36406817; PMCID: PMC9672425.
      View in: PubMed   Mentions: 4  
    19. Rare, Overlooked, or Underappreciated Causes of Recurrent Abdominal Pain: A Primer for Gastroenterologists. Clin Gastroenterol Hepatol. 2023 02; 21(2):264-279. Brenner DM, Brandt LJ, Fenster M, Hamilton MJ, Kamboj AK, Oxentenko AS, Wang B, Chey WD. PMID: 36180010.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    20. Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data. Nat Genet. 2022 10; 54(10):1572-1580. Zhang MJ, Hou K, Dey KK, Sakaue S, Jagadeesh KA, Weinand K, Taychameekiatchai A, Rao P, Pisco AO, Zou J, Wang B, Gandal M, Raychaudhuri S, Pasaniuc B, Price AL. PMID: 36050550; PMCID: PMC9891382.
      View in: PubMed   Mentions: 104     Fields:    
    21. Evidence-based consensus guidelines for the diagnosis and management of erythropoietic protoporphyria and X-linked protoporphyria. J Am Acad Dermatol. 2023 12; 89(6):1227-1237. Dickey AK, Naik H, Keel SB, Levy C, Beaven SW, Elmariah SB, Erwin AL, Goddu RJ, Hedstrom K, Leaf RK, Kazamel M, Mazepa M, Philpotts LL, Quigley J, Raef H, Rudnick SR, Saberi B, Thapar M, Ungar J, Wang B, Balwani M, Porphyrias Consortium of the Rare Diseases Clinical Research Network. PMID: 36041558; PMCID: PMC9968824.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    22. Disease burden in patients with acute hepatic porphyria: experience from the phase 3 ENVISION study. Orphanet J Rare Dis. 2022 08 26; 17(1):327. Wang B, Ventura P, Takase KI, Thapar M, Cassiman D, Kubisch I, Liu S, Sweetser MT, Balwani M. PMID: 36028858; PMCID: PMC9419398.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    23. Single-cell analysis of hepatoblastoma identifies tumor signatures that predict chemotherapy susceptibility using patient-specific tumor spheroids. Nat Commun. 2022 08 25; 13(1):4878. Song H, Bucher S, Rosenberg K, Tsui M, Burhan D, Hoffman D, Cho SJ, Rangaswami A, Breese M, Leung S, Ventura MVP, Sweet-Cordero EA, Huang FW, Nijagal A, Wang B. PMID: 36008377; PMCID: PMC9411569.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    24. The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans. Science. 2022 05 13; 376(6594):eabl4896. Tabula Sapiens Consortium*, Jones RC, Karkanias J, Krasnow MA, Pisco AO, Quake SR, Salzman J, Yosef N, Bulthaup B, Brown P, Harper W, Hemenez M, Ponnusamy R, Salehi A, Sanagavarapu BA, Spallino E, Aaron KA, Concepcion W, Gardner JM, Kelly B, Neidlinger N, Wang Z, Crasta S, Kolluru S, Morri M, Tan SY, Travaglini KJ, Xu C, Alcántara-Hernández M, Almanzar N, Antony J, Beyersdorf B, Burhan D, Calcuttawala K, Carter MM, Chan CKF, Chang CA, Chang S, Colville A, Culver RN, Cvijovic I, D'Amato G, Ezran C, Galdos FX, Gillich A, Goodyer WR, Hang Y, Hayashi A, Houshdaran S, Huang X, Irwin JC, Jang S, Juanico JV, Kershner AM, Kim S, Kiss B, Kong W, Kumar ME, Kuo AH, Li B, Loeb GB, Lu WJ, Mantri S, Markovic M, McAlpine PL, de Morree A, Mrouj K, Mukherjee S, Muser T, Neuhöfer P, Nguyen TD, Perez K, Puluca N, Qi Z, Rao P, Raquer-McKay H, Schaum N, Scott B, Seddighzadeh B, Segal J, Sen S, Sikandar S, Spencer SP, Steffes LC, Subramaniam VR, Swarup A, Swift M, Van Treuren W, Trimm E, Veizades S, Vijayakumar S, Vo KC, Vorperian SK, Wang W, Weinstein HNW, Winkler J, Wu TTH, Xie J, Yung AR, Zhang Y, Detweiler AM, Mekonen H, Neff NF, Sit RV, Tan M, Yan J, Bean GR, Charu V, Forgó E, Martin BA, Ozawa MG, Silva O, Toland A, Vemuri VNP, Afik S, Awayan K, Botvinnik OB, Byrne A, Chen M, Dehghannasiri R, Gayoso A, Granados AA, Li Q, Mahmoudabadi G, McGeever A, Olivieri JE, Park M, Ravikumar N, Stanley G, Tan W, Tarashansky AJ, Vanheusden R, Wang P, Wang S, Xing G, Dethlefsen L, Ezran C, Gillich A, Hang Y, Ho PY, Irwin JC, Jang S, Leylek R, Liu S, Maltzman JS, Metzger RJ, Phansalkar R, Sasagawa K, Sinha R, Song H, Swarup A, Trimm E, Veizades S, Wang B, Beachy PA, Clarke MF, Giudice LC, Huang FW, Huang KC, Idoyaga J, Kim SK, Kuo CS, Nguyen P, Rando TA, Red-Horse K, Reiter J, Relman DA, Sonnenburg JL, Wu A, Wu SM, Wyss-Coray T. PMID: 35549404; PMCID: PMC9812260.
      View in: PubMed   Mentions: 515     Fields:    Translation:HumansCells
    25. Molecular hallmarks of heterochronic parabiosis at single-cell resolution. Nature. 2022 03; 603(7900):309-314. Pálovics R, Keller A, Schaum N, Tan W, Fehlmann T, Borja M, Kern F, Bonanno L, Calcuttawala K, Webber J, McGeever A, Tabula Muris Consortium, Luo J, Pisco AO, Karkanias J, Neff NF, Darmanis S, Quake SR, Wyss-Coray T. PMID: 35236985; PMCID: PMC9387403.
      View in: PubMed   Mentions: 62     Fields:    Translation:Cells
    26. Cell types of origin of the cell-free transcriptome. Nat Biotechnol. 2022 06; 40(6):855-861. Vorperian SK, Moufarrej MN, Tabula Sapiens Consortium, Quake SR. PMID: 35132263; PMCID: PMC9200634.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    27. Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states. Nat Commun. 2022 01 10; 13(1):141. Song H, Weinstein HNW, Allegakoen P, Wadsworth MH, Xie J, Yang H, Castro EA, Lu KL, Stohr BA, Feng FY, Carroll PR, Wang B, Cooperberg MR, Shalek AK, Huang FW. PMID: 35013146; PMCID: PMC8748675.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansCells
    28. Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells. Nat Cell Biol. 2022 01; 24(1):10-23. Kathiriya JJ, Wang C, Zhou M, Brumwell A, Cassandras M, Le Saux CJ, Cohen M, Alysandratos KD, Wang B, Wolters P, Matthay M, Kotton DN, Chapman HA, Peng T. PMID: 34969962; PMCID: PMC8761168.
      View in: PubMed   Mentions: 117     Fields:    Translation:HumansAnimalsCells
    29. RNA splicing programs define tissue compartments and cell types at single-cell resolution. Elife. 2021 09 13; 10. Olivieri JE, Dehghannasiri R, Wang PL, Jang S, de Morree A, Tan SY, Ming J, Ruohao Wu A, Tabula Sapiens Consortium, Quake SR, Krasnow MA, Salzman J. PMID: 34515025; PMCID: PMC8563012.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    30. Novel treatment options for acute hepatic porphyrias. Curr Opin Gastroenterol. 2021 05 01; 37(3):194-199. Wang B. PMID: 33769375; PMCID: PMC8104969.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    31. The acute hepatic porphyrias. Transl Gastroenterol Hepatol. 2021; 6:24. Wang B. PMID: 33824928; PMCID: PMC7838531.
      View in: PubMed   Mentions: 15  
    32. TBX3 functions as a tumor suppressor downstream of activated CTNNB1 mutants during hepatocarcinogenesis. J Hepatol. 2021 07; 75(1):120-131. Liang B, Zhou Y, Qian M, Xu M, Wang J, Zhang Y, Song X, Wang H, Lin S, Ren C, Monga SP, Wang B, Evert M, Chen Y, Chen X, Huang Z, Calvisi DF, Chen X. PMID: 33577921; PMCID: PMC8217095.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    33. Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells. Elife. 2021 01 05; 10. Russell JP, Lim X, Santambrogio A, Yianni V, Kemkem Y, Wang B, Fish M, Haston S, Grabek A, Hallang S, Lodge EJ, Patist AL, Schedl A, Mollard P, Nusse R, Andoniadou CL. PMID: 33399538; PMCID: PMC7803373.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    34. Hepatocellular Carcinoma in Acute Hepatic Porphyrias: Results from the Longitudinal Study of the U.S. Porphyrias Consortium. Hepatology. 2021 05; 73(5):1736-1746. Saberi B, Naik H, Overbey JR, Erwin AL, Anderson KE, Bissell DM, Bonkovsky HL, Phillips JD, Wang B, K Singal A, M McGuire B, Desnick RJ, Balwani M. PMID: 32681675.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    35. Evidence in the UK Biobank for the underdiagnosis of erythropoietic protoporphyria. Genet Med. 2021 01; 23(1):140-148. Dickey AK, Quick C, Ducamp S, Zhu Z, Feng YA, Naik H, Balwani M, Anderson KE, Lin X, Phillips JE, Rebeiz L, Bonkovsky HL, McGuire BM, Wang B, Chasman DI, Smoller JW, Fleming MD, Christiani DC. PMID: 32873934; PMCID: PMC7796935.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    36. A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Nature. 2020 07; 583(7817):590-595. Tabula Muris Consortium. PMID: 32669714; PMCID: PMC8240505.
      View in: PubMed   Mentions: 516     Fields:    Translation:AnimalsCells
    37. Ageing hallmarks exhibit organ-specific temporal signatures. Nature. 2020 07; 583(7817):596-602. Schaum N, Lehallier B, Hahn O, Pálovics R, Hosseinzadeh S, Lee SE, Sit R, Lee DP, Losada PM, Zardeneta ME, Fehlmann T, Webber JT, McGeever A, Calcuttawala K, Zhang H, Berdnik D, Mathur V, Tan W, Zee A, Tan M, Tabula Muris Consortium, Pisco AO, Karkanias J, Neff NF, Keller A, Darmanis S, Quake SR, Wyss-Coray T. PMID: 32669715; PMCID: PMC7757734.
      View in: PubMed   Mentions: 315     Fields:    Translation:AnimalsCells
    38. Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria. N Engl J Med. 2020 06 11; 382(24):2289-2301. Balwani M, Sardh E, Ventura P, Peiró PA, Rees DC, Stölzel U, Bissell DM, Bonkovsky HL, Windyga J, Anderson KE, Parker C, Silver SM, Keel SB, Wang JD, Stein PE, Harper P, Vassiliou D, Wang B, Phillips J, Ivanova A, Langendonk JG, Kauppinen R, Minder E, Horie Y, Penz C, Chen J, Liu S, Ko JJ, Sweetser MT, Garg P, Vaishnaw A, Kim JB, Simon AR, Gouya L, ENVISION Investigators. PMID: 32521132.
      View in: PubMed   Mentions: 253     Fields:    Translation:HumansCTClinical Trials
    39. Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation. Sci Rep. 2020 04 28; 10(1):7165. Alkhani A, Levy CS, Tsui M, Rosenberg KA, Polovina K, Mattis AN, Mack M, Van Dyken S, Wang BM, Maher JJ, Nijagal A. PMID: 32346042; PMCID: PMC7188847.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    40. mTORC2 Signaling Is Necessary for Timely Liver Regeneration after Partial Hepatectomy. Am J Pathol. 2020 04; 190(4):817-829. Xu M, Wang H, Wang J, Burhan D, Shang R, Wang P, Zhou Y, Li R, Liang B, Evert K, Utpatel K, Xu Z, Song X, Che L, Calvisi DF, Wang B, Chen X, Zeng Y, Chen X. PMID: 32035060; PMCID: PMC7180798.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    41. Evaluating the Patient-Reported Outcomes Measurement Information System scales in acute intermittent porphyria. Genet Med. 2020 03; 22(3):590-597. Naik H, Overbey JR, Montgomery GH, Winkel G, Balwani M, Anderson KE, Bissell DM, Bonkovsky HL, Phillips JD, Wang B, McGuire B, Keel S, Levy C, Erwin A, Desnick RJ. PMID: 31690837; PMCID: PMC7060090.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    42. Evaluating quality of life tools in North American patients with erythropoietic protoporphyria and X-linked protoporphyria. JIMD Rep. 2019 Nov; 50(1):9-19. Naik H, Overbey JR, Desnick RJ, Anderson KE, Bissell DM, Bloomer J, Bonkovsky HL, Phillips JD, Wang B, Singal A, Balwani M. PMID: 31741822; PMCID: PMC6850979.
      View in: PubMed   Mentions: 18  
    43. Axis inhibition protein 1 (Axin1) Deletion-Induced Hepatocarcinogenesis Requires Intact β-Catenin but Not Notch Cascade in Mice. Hepatology. 2019 12; 70(6):2003-2017. Qiao Y, Wang J, Karagoz E, Liang B, Song X, Shang R, Evert K, Xu M, Che L, Evert M, Calvisi DF, Tao J, Wang B, Monga SP, Chen X. PMID: 30737831; PMCID: PMC7206928.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    44. Tissue Repair in the Mouse Liver Following Acute Carbon Tetrachloride Depends on Injury-Induced Wnt/β-Catenin Signaling. Hepatology. 2019 06; 69(6):2623-2635. Zhao L, Jin Y, Donahue K, Tsui M, Fish M, Logan CY, Wang B, Nusse R. PMID: 30762896; PMCID: PMC7043939.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    45. Acute Hepatic Porphyrias: Review and Recent Progress. Hepatol Commun. 2019 Feb; 3(2):193-206. Wang B, Rudnick S, Cengia B, Bonkovsky HL. PMID: 30766957; PMCID: PMC6357830.
      View in: PubMed   Mentions: 63     Fields:    
    46. Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture. Cell. 2018 11 29; 175(6):1607-1619.e15. Peng WC, Logan CY, Fish M, Anbarchian T, Aguisanda F, Álvarez-Varela A, Wu P, Jin Y, Zhu J, Li B, Grompe M, Wang B, Nusse R. PMID: 30500539; PMCID: PMC6497386.
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    47. Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris. Nature. 2018 10; 562(7727):367-372. Tabula Muris Consortium, Overall coordination, Logistical coordination, Organ collection and processing, Library preparation and sequencing, Computational data analysis, Cell type annotation, Writing group, Supplemental text writing group, Principal investigators. PMID: 30283141; PMCID: PMC6642641.
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    48. Acute hepatic porphyrias: Recommendations for evaluation and long-term management. Hepatology. 2017 10; 66(4):1314-1322. Balwani M, Wang B, Anderson KE, Bloomer JR, Bissell DM, Bonkovsky HL, Phillips JD, Desnick RJ, Porphyrias Consortium of the Rare Diseases Clinical Research Network. PMID: 28605040; PMCID: PMC5605422.
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    49. Clinical, Biochemical, and Genetic Characterization of North American Patients With Erythropoietic Protoporphyria and X-linked Protoporphyria. JAMA Dermatol. 2017 08 01; 153(8):789-796. Balwani M, Naik H, Anderson KE, Bissell DM, Bloomer J, Bonkovsky HL, Phillips JD, Overbey JR, Wang B, Singal AK, Liu LU, Desnick RJ. PMID: 28614581; PMCID: PMC5710403.
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    50. Pitfalls in Erythrocyte Protoporphyrin Measurement for Diagnosis and Monitoring of Protoporphyrias. Clin Chem. 2015 Dec; 61(12):1453-6. Gou EW, Balwani M, Bissell DM, Bloomer JR, Bonkovsky HL, Desnick RJ, Naik H, Phillips JD, Singal AK, Wang B, Keel S, Anderson KE. PMID: 26482161; PMCID: PMC4744648.
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    51. Self-renewing diploid Axin2(+) cells fuel homeostatic renewal of the liver. Nature. 2015 Aug 13; 524(7564):180-5. Wang B, Zhao L, Fish M, Logan CY, Nusse R. PMID: 26245375; PMCID: PMC4589224.
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    52. Acute Hepatic Porphyria. J Clin Transl Hepatol. 2015 Mar; 3(1):17-26. Bissell DM, Wang B. PMID: 26357631; PMCID: PMC4542079.
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    53. Acute liver failure with thyrotoxicosis treated with liver transplantation. Endocr Pract. 2013 May-Jun; 19(3):e57-60. Cascino MD, McNabb B, Gardner DG, Woeber KA, Fox AN, Wang B, Fix OK. PMID: 23337142.
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    54. Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration. J Clin Invest. 2011 Dec; 121(12):4850-60. Malato Y, Naqvi S, Schürmann N, Ng R, Wang B, Zape J, Kay MA, Grimm D, Willenbring H. PMID: 22105172; PMCID: PMC3226005.
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    55. Role of alphavbeta6 integrin in acute biliary fibrosis. Hepatology. 2007 Nov; 46(5):1404-12. Wang B, Dolinski BM, Kikuchi N, Leone DR, Peters MG, Weinreb PH, Violette SM, Bissell DM. PMID: 17924447; PMCID: PMC4144397.
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    56. Six decades of progress and change in hospital medicine, 1947-2007. Pharos Alpha Omega Alpha Honor Med Soc. 2007; 70(1):10-5. Wang B, Dhaliwal G, Sleisenger MH. PMID: 17357747.
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    57. TWEAK induces liver progenitor cell proliferation. J Clin Invest. 2005 Sep; 115(9):2330-40. Jakubowski A, Ambrose C, Parr M, Lincecum JM, Wang MZ, Zheng TS, Browning B, Michaelson JS, Baetscher M, Baestcher M, Wang B, Bissell DM, Burkly LC. PMID: 16110324; PMCID: PMC1187931.
      View in: PubMed   Mentions: 192     Fields:    Translation:HumansAnimalsCells
    58. Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton. Cell. 2001 Apr 06; 105(1):81-91. Winter CG, Wang B, Ballew A, Royou A, Karess R, Axelrod JD, Luo L. PMID: 11301004.
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    59. Hereditary Coproporphyria. GeneReviews®. 1993. Wang B, Bissell DM. View Publication.
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