 Elizabeth Crouch, MD, PhD
 Biography | DePauw University, Greencastle, IN | BA | | Biochemistry | | Columbia University, New York, NY | MD | | Medicine | | Columbia University, New York, NY | PhD | | Neuroscience | | University of California, San Francisco, San Francisco, CA | Residency | | Pediatrics | | University of California, San Francisco, San Francisco, CA | Fellowship | | Neonatology |
Overview I am a neuroscientist, a vascular biologist, and a physician in Neonatal-Perinatal medicine. My lab, the Neurovascular Development lab, studies how brain blood vessels grow and interact with other brain cells. In part, this interest is inspired from the preterm babies that I care for clinically. Approximately 20% of preterm babies born between 24-28 gestation weeks will develop germinal matrix hemorrhage (GMH). This hemorrhage can cause hydrocephalus, cerebral palsy, and death, and unfortunately there are currently no treatments. Our lab uses neuropathological specimens, flow cytometry (FACS), bioinformatics, and cell culture, including organoid models, to interrogate brain vascular biology. We are always interested in hiring motivated and talented individuals. Send an email to inquire; women and URM especially encouraged to apply.
Research ORNG Applications Bibliographic
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
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Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
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Tropism of SARS-CoV-2 for Developing Human Cortical Astrocytes. bioRxiv. 2021 Jan 18.
Andrews MG, Mukhtar T, Eze UC, Simoneau CR, Perez Y, Mostajo-Radji MA, Wang S, Velmeshev D, Salma J, Kumar GR, Pollen AA, Crouch EE, Ott M, Kriegstein AR. PMID: 33469577.
View in: PubMed Mentions:
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The Expanding Cell Diversity of the Brain Vasculature. Front Physiol. 2020; 11:600767.
Ross JM, Kim C, Allen D, Crouch EE, Narsinh K, Cooke DL, Abla AA, Nowakowski TJ, Winkler EA. PMID: 33343397.
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Reciprocal Interaction between Vascular Filopodia and Neural Stem Cells Shapes Neurogenesis in the Ventral Telencephalon. Cell Rep. 2020 Oct 13; 33(2):108256.
Di Marco B, Crouch EE, Shah B, Duman C, Paredes MF, Ruiz de Almodovar C, Huang EJ, Alfonso J. PMID: 33053356.
View in: PubMed Mentions: Fields:
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Human organoids to model the developing human neocortex in health and disease. Brain Res. 2020 09 01; 1742:146803.
Khakipoor S, Crouch EE, Mayer S. PMID: 32240655.
View in: PubMed Mentions: 1 Fields:
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Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma. Cell Stem Cell. 2020 01 02; 26(1):48-63.e6.
Bhaduri A, Di Lullo E, Jung D, Müller S, Crouch EE, Espinosa CS, Ozawa T, Alvarado B, Spatazza J, Cadwell CR, Wilkins G, Velmeshev D, Liu SJ, Malatesta M, Andrews MG, Mostajo-Radji MA, Huang EJ, Nowakowski TJ, Lim DA, Diaz A, Raleigh DR, Kriegstein AR. PMID: 31901251.
View in: PubMed Mentions: 14 Fields:
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FACS isolation of endothelial cells and pericytes from mouse brain microregions. Nat Protoc. 2018 04; 13(4):738-751.
Crouch EE, Doetsch F. PMID: 29565899.
View in: PubMed Mentions: 12 Fields: Translation: AnimalsCells
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Regional and stage-specific effects of prospectively purified vascular cells on the adult V-SVZ neural stem cell lineage. J Neurosci. 2015 Mar 18; 35(11):4528-39.
Crouch EE, Liu C, Silva-Vargas V, Doetsch F. PMID: 25788671.
View in: PubMed Mentions: 30 Fields: Translation: AnimalsCells
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Novel association of early onset hepatocellular carcinoma with transaldolase deficiency. JIMD Rep. 2014; 12:121-7.
Leduc CA, Crouch EE, Wilson A, Lefkowitch J, Wamelink MM, Jakobs C, Salomons GS, Sun X, Shen Y, Chung WK. PMID: 24097415.
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Adult neural stem cells and their niche: a dynamic duo during homeostasis, regeneration, and aging. Curr Opin Neurobiol. 2013 Dec; 23(6):935-42.
Silva-Vargas V, Crouch EE, Doetsch F. PMID: 24090877.
View in: PubMed Mentions: 45 Fields: Translation: HumansAnimalsCells
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The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks. Nature. 2007 Jun 07; 447(7145):730-4.
Kruhlak M, Crouch EE, Orlov M, Montaño C, Gorski SA, Nussenzweig A, Misteli T, Phair RD, Casellas R. PMID: 17554310.
View in: PubMed Mentions: 125 Fields: Translation: AnimalsCells
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Regulation of AID expression in the immune response. J Exp Med. 2007 May 14; 204(5):1145-56.
Crouch EE, Li Z, Takizawa M, Fichtner-Feigl S, Gourzi P, Montaño C, Feigenbaum L, Wilson P, Janz S, Papavasiliou FN, Casellas R. PMID: 17452520.
View in: PubMed Mentions: 109 Fields: Translation: AnimalsCells
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| Year | Publications |
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| 2007 | 2 | | 2013 | 2 | | 2015 | 1 | | 2018 | 1 | | 2020 | 4 | | 2021 | 1 |
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This graph shows the number and percent of publications by field.
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