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Oscar Aguilar Alfaro, PhD

Title(s)Postdoctoral Scholar, Microbiology and Immunology
SchoolSchool of Medicine
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    Collapse Biography 
    Collapse Education and Training
    Carleton University, Ottawa, ON, CanadaBSc06/2007Biochemistry
    Carleton University, Ottawa, ON, CanadaMSc08/2009Biology
    University of Toronto, Toronto, ON, CanadaPhD04/2017Immunology

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Weizman OE, Song E, Adams NM, Hildreth AD, Riggan L, Krishna C, Aguilar OA, Leslie CS, Carlyle JR, Sun JC, O'Sullivan TE. Mouse cytomegalovirus-experienced ILC1s acquire a memory response dependent on the viral glycoprotein m12. Nat Immunol. 2019 Jul 01. PMID: 31263280.
      View in: PubMed
    2. Balaji GR, Aguilar OA, Tanaka M, Shingu-Vazquez MA, Fu Z, Gully BS, Lanier LL, Carlyle JR, Rossjohn J, Berry R. Recognition of host Clr-b by the inhibitory NKR-P1B receptor provides a basis for missing-self recognition. Nat Commun. 2018 11 05; 9(1):4623. PMID: 30397201.
      View in: PubMed
    3. Abou-Samra E, Hickey Z, Aguilar OA, Scur M, Mahmoud AB, Pyatibrat S, Tu MM, Francispillai J, Mortha A, Carlyle JR, Rahim MMA, Makrigiannis AP. NKR-P1B expression in gut-associated innate lymphoid cells is required for the control of gastrointestinal tract infections. Cell Mol Immunol. 2018 Oct 01. PMID: 30275537.
      View in: PubMed
    4. Tanaka M, Fine JH, Kirkham CL, Aguilar OA, Belcheva A, Martin A, Ketela T, Moffat J, Allan DSJ, Carlyle JR. The Inhibitory NKR-P1B:Clr-b Recognition Axis Facilitates Detection of Oncogenic Transformation and Cancer Immunosurveillance. Cancer Res. 2018 Jul 01; 78(13):3589-3603. PMID: 29691253.
      View in: PubMed
    5. Allan DSJ, Cerdeira AS, Ranjan A, Kirkham CL, Aguilar OA, Tanaka M, Childs RW, Dunbar CE, Strominger JL, Kopcow HD, Carlyle JR. Transcriptome analysis reveals similarities between human blood CD3- CD56bright cells and mouse CD127+ innate lymphoid cells. Sci Rep. 2017 06 14; 7(1):3501. PMID: 28615725.
      View in: PubMed
    6. Aguilar OA, Berry R, Rahim MMA, Reichel JJ, Popovic B, Tanaka M, Fu Z, Balaji GR, Lau TNH, Tu MM, Kirkham CL, Mahmoud AB, Mesci A, Krmpotic A, Allan DSJ, Makrigiannis AP, Jonjic S, Rossjohn J, Carlyle JR. A Viral Immunoevasin Controls Innate Immunity by Targeting the Prototypical Natural Killer Cell Receptor Family. Cell. 2017 03 23; 169(1):58-71.e14. PMID: 28340350.
      View in: PubMed
    7. Kirkham CL, Aguilar OA, Yu T, Tanaka M, Mesci A, Chu KL, Fine JH, Mossman KL, Bremner R, Allan DSJ, Carlyle JR. Interferon-Dependent Induction of Clr-b during Mouse Cytomegalovirus Infection Protects Bystander Cells from Natural Killer Cells via NKR-P1B-Mediated Inhibition. J Innate Immun. 2017; 9(4):343-358. PMID: 28288457.
      View in: PubMed
    8. Rahim MM, Wight A, Mahmoud AB, Aguilar OA, Lee SH, Vidal SM, Carlyle JR, Makrigiannis AP. Expansion and Protection by a Virus-Specific NK Cell Subset Lacking Expression of the Inhibitory NKR-P1B Receptor during Murine Cytomegalovirus Infection. J Immunol. 2016 09 15; 197(6):2325-37. PMID: 27511735.
      View in: PubMed
    9. Aguilar OA, Mesci A, Ma J, Chen P, Kirkham CL, Hundrieser J, Voigt S, Allan DS, Carlyle JR. Modulation of Clr Ligand Expression and NKR-P1 Receptor Function during Murine Cytomegalovirus Infection. J Innate Immun. 2015; 7(6):584-600. PMID: 26044139.
      View in: PubMed
    10. Chen P, Aguilar OA, Rahim MM, Allan DS, Fine JH, Kirkham CL, Ma J, Tanaka M, Tu MM, Wight A, Kartsogiannis V, Gillespie MT, Makrigiannis AP, Carlyle JR. Genetic investigation of MHC-independent missing-self recognition by mouse NK cells using an in vivo bone marrow transplantation model. J Immunol. 2015 Mar 15; 194(6):2909-18. PMID: 25681346.
      View in: PubMed
    11. Karimi MA, Aguilar O, Zou B, Bachmann MH, Carlyle JR, Baldwin CL, Kambayashi T. A truncated human NKG2D splice isoform negatively regulates NKG2D-mediated function. J Immunol. 2014 Sep 15; 193(6):2764-2771. PMID: 25092887.
      View in: PubMed
    12. Chen P, BĂ©langer S, Aguilar OA, Zhang Q, St-Laurent A, Rahim MM, Makrigiannis AP, Carlyle JR. Analysis of the mouse 129-strain Nkrp1-Clr gene cluster reveals conservation of genomic organization and functional receptor-ligand interactions despite significant allelic polymorphism. Immunogenetics. 2011 Oct; 63(10):627-40. PMID: 21667046.
      View in: PubMed