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    Anita Sil, MD, PhD

    TitleAssociate Professor
    SchoolUCSF School of Medicine
    DepartmentMicrobiology and Immunology
    Address513 Parnassus Ave, Med Sci
    San Francisco CA 94143
    Phone415-502-1805
      Other Positions
      TitleHoward Hughes Investigator


       Biography 
       Education and Training
      Institution Degree School or Department Year
      University of California, San FranciscoM.D. Medicine1998
      University of California, San FranciscoPh.D. Graduate Division (Biochemistry)1996

       ORNG Applications 
       Websites
       Awarded Grants
       Global Health
       More Info

       Bibliographic 
       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Gilmore SA, Naseem S, Konopka JB, Sil A. N-acetylglucosamine (GlcNAc) triggers a rapid, temperature-responsive morphogenetic program in thermally dimorphic fungi. PLoS Genet. 2013; 9(9):e1003799.
        View in: PubMed
      2. Beyhan S, Gutierrez M, Voorhies M, Sil A. A temperature-responsive network links cell shape and virulence traits in a primary fungal pathogen. PLoS Biol. 2013 Jul; 11(7):e1001614.
        View in: PubMed
      3. Inglis DO, Voorhies M, Hocking Murray DR, Sil A. Comparative transcriptomics of infectious spores from the fungal pathogen Histoplasma capsulatum reveals a core set of transcripts that specify infectious and pathogenic states. Eukaryot Cell. 2013 Jun; 12(6):828-52.
        View in: PubMed
      4. Isaac DT, Coady A, Van Prooyen N, Sil A. The 3-hydroxy-methylglutaryl coenzyme A lyase HCL1 is required for macrophage colonization by human fungal pathogen Histoplasma capsulatum. Infect Immun. 2013 Feb; 81(2):411-20.
        View in: PubMed
      5. Muhammed M, Feldmesser M, Shubitz LF, Lionakis MS, Sil A, Wang Y, Glavis-Bloom J, Lewis RE, Galgiani JN, Casadevall A, Kontoyiannis DP, Mylonakis E. Mouse models for the study of fungal pneumonia: a collection of detailed experimental protocols for the study of Coccidioides, Cryptococcus, Fusarium, Histoplasma and combined infection due to Aspergillus-Rhizopus. Virulence. 2012 May 1; 3(3):329-38.
        View in: PubMed
      6. Hwang LH, Seth E, Gilmore SA, Sil A. SRE1 regulates iron-dependent and -independent pathways in the fungal pathogen Histoplasma capsulatum. Eukaryot Cell. 2012 Jan; 11(1):16-25.
        View in: PubMed
      7. Cain CW, Lohse MB, Homann OR, Sil A, Johnson AD. A conserved transcriptional regulator governs fungal morphology in widely diverged species. Genetics. 2012 Feb; 190(2):511-21.
        View in: PubMed
      8. Voorhies M, Foo CK, Sil A. Experimental annotation of the human pathogen Histoplasma capsulatum transcribed regions using high-resolution tiling arrays. BMC Microbiol. 2011; 11:216.
        View in: PubMed
      9. Inglis DO, Berkes CA, Hocking Murray DR, Sil A. Conidia but not yeast cells of the fungal pathogen Histoplasma capsulatum trigger a type I interferon innate immune response in murine macrophages. Infect Immun. 2010 Sep; 78(9):3871-82.
        View in: PubMed
      10. Webster RH, Sil A. Conserved factors Ryp2 and Ryp3 control cell morphology and infectious spore formation in the fungal pathogen Histoplasma capsulatum. Proc Natl Acad Sci U S A. 2008 Sep 23; 105(38):14573-8.
        View in: PubMed
      11. Hwang LH, Mayfield JA, Rine J, Sil A. Histoplasma requires SID1, a member of an iron-regulated siderophore gene cluster, for host colonization. PLoS Pathog. 2008 Apr; 4(4):e1000044.
        View in: PubMed
      12. Nguyen VQ, Sil A. Temperature-induced switch to the pathogenic yeast form of Histoplasma capsulatum requires Ryp1, a conserved transcriptional regulator. Proc Natl Acad Sci U S A. 2008 Mar 25; 105(12):4880-5.
        View in: PubMed
      13. Fraser JA, Stajich JE, Tarcha EJ, Cole GT, Inglis DO, Sil A, Heitman J. Evolution of the mating type locus: insights gained from the dimorphic primary fungal pathogens Histoplasma capsulatum, Coccidioides immitis, and Coccidioides posadasii. Eukaryot Cell. 2007 Apr; 6(4):622-9.
        View in: PubMed
      14. Gebhart D, Bahrami AK, Sil A. Identification of a copper-inducible promoter for use in ectopic expression in the fungal pathogen Histoplasma capsulatum. Eukaryot Cell. 2006 Jun; 5(6):935-44.
        View in: PubMed
      15. Nittler MP, Hocking-Murray D, Foo CK, Sil A. Identification of Histoplasma capsulatum transcripts induced in response to reactive nitrogen species. Mol Biol Cell. 2005 Oct; 16(10):4792-813.
        View in: PubMed
      16. Hwang L, Hocking-Murray D, Bahrami AK, Andersson M, Rine J, Sil A. Identifying phase-specific genes in the fungal pathogen Histoplasma capsulatum using a genomic shotgun microarray. Mol Biol Cell. 2003 Jun; 14(6):2314-26.
        View in: PubMed
      17. Sil AK, Xin P, Hopper JE. Vectors allowing amplified expression of the Saccharomyces cerevisiae Gal3p-Gal80p-Gal4p transcription switch: applications to galactose-regulated high-level production of proteins. Protein Expr Purif. 2000 Mar; 18(2):202-12.
        View in: PubMed
      18. Sil AK, Alam S, Xin P, Ma L, Morgan M, Lebo CM, Woods MP, Hopper JE. The Gal3p-Gal80p-Gal4p transcription switch of yeast: Gal3p destabilizes the Gal80p-Gal4p complex in response to galactose and ATP. Mol Cell Biol. 1999 Nov; 19(11):7828-40.
        View in: PubMed
      19. Takizawa PA, Sil A, Swedlow JR, Herskowitz I, Vale RD. Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast. Nature. 1997 Sep 4; 389(6646):90-3.
        View in: PubMed
      20. Sil A, Herskowitz I. Identification of asymmetrically localized determinant, Ash1p, required for lineage-specific transcription of the yeast HO gene. Cell. 1996 Mar 8; 84(5):711-22.
        View in: PubMed
      21. Kruger W, Peterson CL, Sil A, Coburn C, Arents G, Moudrianakis EN, Herskowitz I. Amino acid substitutions in the structured domains of histones H3 and H4 partially relieve the requirement of the yeast SWI/SNF complex for transcription. Genes Dev. 1995 Nov 15; 9(22):2770-9.
        View in: PubMed
      22. Pryciak PM, Sil A, Varmus HE. Retroviral integration into minichromosomes in vitro. EMBO J. 1992 Jan; 11(1):291-303.
        View in: PubMed
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