Laurence Huang, MD
|School||UCSF School of Medicine|
|Address||1001 Potrero Ave, SFGH 80|
|San Francisco General Hospital||2014||Henry F. (Chip) Chambers Medicine Service Subspecialist Consultant of|
|University of California San Francisco Positive Health Program, HIV/AIDS Division||2009||Positive Health Program Award for Teaching Excellence-Meg Newman Teaching Award|
|University of California San Francisco AIDS Research Institute||2005||George S. Sarlo Award for Excellence in Teaching and Mentoring|
|University of California San Francisco ||2005||Haile T. Debas Academy of Medical Educators Excellence in Direct Teaching Award|
|Centers for Disease Control and Prevention||2001||James H. Nakano Citation (for Outstanding Scientific Paper published in 2000)|
|American College of Physicians-American Society of Internal Medicine||2000||Community Based Teaching Excellence and Preceptorship Award|
|Desert AIDS Project-presented to members of San Francisco General Hospital’s Inpatient AIDS Unit||1998||4th Annual Steve Chase Humanitarian Award|
|American Lung Association ||1995||Walter Travel Fund Award|
|Johns Hopkins University||1984||Omicron Delta Kappa-National Leadership Honor Society|
I am a pulmonary and critical care medicine specialist with a research focus on pulmonary diseases affecting persons with HIV. Currently, I am PI/Co-PI on 2 main studies:
IHOP: The International HIV-associated Opportunistic Pneumonias (IHOP) Study is a multi-national cohort study whose goal is to improve our understanding of the epidemiology, etiology, and outcome of pneumonias in persons with HIV infection. IHOP is part of the Lung HIV Study, a collaborative multi-R01 consortium established by the National Heart, Lung, and Blood Institute (NHLBI) to examine a diverse range of infectious and non-infectious pulmonary diseases in HIV-infected persons.
Lung MicroChip: The Lung Microbiome in Cohorts of HIV-Infected Persons (Lung MicroChip) Study is a multi-cohort study whose goal is to examine the composition and function of the lung microbiome in persons with HIV. Lung MicroChip is part of the Lung HIV Microbiome Project, a collaborative multi-U01 consortium established by the NHLBI to study the lung microbiome in HIV infection.
I am also engaged in research on aging-associated lung diseases in HIV-infected persons (primarily pneumonia and chronic obstructive pulmonary disease, COPD) with the I AM OLD Study (Inflammation, Aging, Microbes and Obstructive Lung Disease).
1. Determine the etiology and mortality of HIV-associated opportunistic pneumonias in an international, multi-center, longitudinal cohort
2. Study PCP epidemiology, diagnosis, drug-resistance, and host immune response
3. Develop and validate new molecular applications to study PCP, TB, and other HIV-associated opportunistic pneumonias
4. Study the composition and function of the lung microbiome in persons with HIV infection
5. Study the impact of chronic inflammation, telomere length, telomerase activity, and pneumonia on the development and progression of HIV-associated COPD
6. Examine whether PCP results from person-to-person transmission (as has been convincingly demonstrated from animal-to-animal laboratory studies) and whether disease results from reactivation of latent infection or from recent exposure and infection
HIV-associated pulmonary diseases, Pneumocystis pneumonia (PCP), Mycobacterium tuberculosis (TB), Bacterial pneumonia, Pulmonary Kaposi sarcoma (KS), HIV-associated chronic obstructive pulmonary disease (COPD), HIV-associated pulmonary arterial hypertension (PAH), Intensive care of HIV-infected persons, Diagnosis of HIV-associated pulmonary diseases in low income countries, Application of microarrays and Next Generation sequencing to HIV-associated pulmonary diseases
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