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Erin Gordon, MD

TitleAssistant Professor
SchoolUCSF School of Medicine
DepartmentMedicine
Address513 Parnassus Ave
San Francisco CA 94143
Phone415-476-0752
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    Collapse Biography 
    Collapse Education and Training
    University of California, BerkeleyB.A. 2001Molecular Cell Biology
    University of Southern CaliforniaM.D.2005School of Medicine
    University of California, San DiegoInternal Medicine
    University of California, San FranciscoPulmonary and Critical Care Fellowship

    Collapse Overview 
    Collapse Overview
    I am a physician-scientist with an interest in airway epithelial dysfunction in asthma. Specifically, my lab focuses on understanding how genetic risk variants that are associated with asthma at a population level, actually confer risk of disease at a molecular level. We use novel techniques such as conditionally reprogrammed primary airway epithelial cells, CRISPR gene deletion, and biospecimens from large numbers of human subjects to discover the function of genes associated with asthma and elucidate the causal single nucleotide polymorphism. These efforts are designed to uncover novel drug targets and define the subpopulation of asthmatics most likely to benefit from therapy.


    Collapse Research 
    Collapse Research Activities and Funding
    The function and regulation of IL-33 in the airway epithelium in asthma
    NIH/NHLBI K08HL114645Aug 1, 2013 - May 31, 2018
    Role: Principal Investigator
    Periostin induces matrix stiffness and epithelial cell mesenchymal transition
    NIH/NHLBI F32HL107004Jan 1, 2011 - Dec 31, 2011
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Lachowicz-Scroggins ME, Finkbeiner WE, Gordon E, Yuan S, Zlock L, Bhakta NR, Woodruff PG, Fahy JV, Boushey HA. Corticosteroid and Long-Acting ß-Agonist Therapy Reduces Epithelial Goblet Cell Metaplasia. Clin Exp Allergy. 2017 Aug 22. PMID: 28833774.
      View in: PubMed
    2. Gordon E, Palandra J, Wesolowska-Andersen A, Ringel L, Rios CL, Lachowicz-Scroggins ME, Sharp LZ, Everman JL, MacLeod HJ, Lee JW, Mason RJ, Matthay MA, Sheldon RT, Peters MC, Nocka KH, Fahy JV, Seibold MA. IL1RL1 asthma risk variants regulate airway type 2 inflammation. JCI Insight. 2016 Sep 8; 1(14):e87871. PMID: 27699235.
      View in: PubMed
    3. Gordon E, Simpson LJ, Rios CL, Ringel L, Lachowicz-Scroggins ME, Peters MC, Wesolowska-Andersen A, Gonzalez JR, MacLeod HJ, Christian LS, Yuan S, Barry L, Woodruff PG, Ansel KM, Nocka K, Seibold MA, Fahy JV, et al. Alternative splicing of interleukin-33 and type 2 inflammation in asthma. Proc Natl Acad Sci U S A. 2016 Jul 18. PMID: 27432971.
      View in: PubMed
    4. Gordon E, Locksley RM, Fahy JV. Cross-Talk between Epithelial Cells and Type 2 Immune Signaling. The Role of IL-25. Am J Respir Crit Care Med. 2016 May 1; 193(9):935-6. PMID: 27128698.
      View in: PubMed
    5. Sweerus K, Lachowicz-Scroggins M, Gordon E, LaFemina M, Huang X, Parikh M, Kanegai C, Fahy JV, Frank JA. Claudin-18 deficiency is associated with airway epithelial barrier dysfunction and asthma. J Allergy Clin Immunol. 2016 Apr 20. PMID: 27215490.
      View in: PubMed
    6. Gordon E, Sidhu SS, Wang ZE, Woodruff PG, Yuan S, Solon MC, Conway SJ, Huang X, Locksley RM, Fahy JV. A protective role for periostin and TGF-ß in IgE-mediated allergy and airway hyperresponsiveness. Clin Exp Allergy. 2012 Jan; 42(1):144-55. PMID: 22093101; PMCID: PMC3271792.
      View in: PubMed, PubMed Central
    7. Gordon E, Lazarus SC. Management of chronic obstructive pulmonary disease: moving beyond the asthma algorithm. J Allergy Clin Immunol. 2009 Nov; 124(5):873-80; quiz 881-2. PMID: 19895979.
      View in: PubMed
    8. Ferrada MA, Gordon E, Jen KY, He HZ, Lu X, Barone LM, Amirifeli S, Perkins DL, Finn PW. (R)-albuterol decreases immune responses: role of activated T cells. Respir Res. 2008; 9:3. PMID: 18194569; PMCID: PMC2253534.
      View in: PubMed, PubMed Central
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