Erin Gordon, MD
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Title(s) | Assistant Professor, Medicine |
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School | School of Medicine |
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Address | 513 Parnassus Ave, HSE San Francisco CA 94143
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Phone | 415-476-0735 |
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vCard | Download vCard |
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Biography University of California, Berkeley | B.A. | 2001 | Molecular Cell Biology | University of Southern California | M.D. | 2005 | School of Medicine | University of California, San Diego | Internal Medicine | | | University of California, San Francisco | Pulmonary and Critical Care Fellowship | | |
Overview I am a physician-scientist with an interest in airway epithelial dysfunction in asthma. Specifically, my lab focuses on understanding how genetic risk variants that are associated with asthma at a population level, actually confer risk of disease at a molecular level. We use novel techniques such as conditionally reprogrammed primary airway epithelial cells, CRISPR gene deletion, and biospecimens from large numbers of human subjects to discover the function of genes associated with asthma and elucidate the causal single nucleotide polymorphism. These efforts are designed to uncover novel drug targets and define the subpopulation of asthmatics most likely to benefit from therapy.
Research ORNG Applications Bibliographic
Altmetrics Details
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
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Cystic Fibrosis Lung Transplant Recipients Have Suppressed Airway Interferon Responses during Pseudomonas Infection. Cell Rep Med. 2020 Jul 21; 1(4).
PMID: 32754722.
View in: PubMed Mentions:
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Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma. Am J Respir Crit Care Med. 2019 05 01; 199(9):1076-1085.
Lachowicz-Scroggins ME, Dunican EM, Charbit AR, Raymond W, Looney MR, Peters MC, Gordon ED, Woodruff PG, Lefrançais E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Hastie AT, Bleecker ER, Fajt ML, Wenzel SE, Israel E, Levy BD, Fahy JV. PMID: 30888839.
View in: PubMed Mentions: 20 Fields: Translation: HumansCells
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Cadherin-26 (CDH26) regulates airway epithelial cell cytoskeletal structure and polarity. Cell Discov. 2018; 4:7.
Lachowicz-Scroggins ME, Gordon ED, Wesolowska-Andersen A, Jackson ND, MacLeod HJ, Sharp LZ, Sun M, Seibold MA, Fahy JV. PMID: 29449961.
View in: PubMed Mentions:
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Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. J Clin Invest. 2018 03 01; 128(3):997-1009.
PMID: 29400693.
View in: PubMed Mentions: 33 Fields: Translation: Humans
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Corticosteroid and long-acting ß-agonist therapy reduces epithelial goblet cell metaplasia. Clin Exp Allergy. 2017 Dec; 47(12):1534-1545.
PMID: 28833774.
View in: PubMed Mentions: 5 Fields: Translation: HumansCells
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IL1RL1 asthma risk variants regulate airway type 2 inflammation. JCI Insight. 2016 09 08; 1(14):e87871.
PMID: 27699235.
View in: PubMed Mentions: 10 Fields: Translation: HumansCells
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Alternative splicing of interleukin-33 and type 2 inflammation in asthma. Proc Natl Acad Sci U S A. 2016 08 02; 113(31):8765-70.
PMID: 27432971.
View in: PubMed Mentions: 36 Fields: Translation: HumansCells
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Cross-Talk between Epithelial Cells and Type 2 Immune Signaling. The Role of IL-25. Am J Respir Crit Care Med. 2016 05 01; 193(9):935-6.
PMID: 27128698.
View in: PubMed Mentions: 3 Fields: Translation: HumansCells
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Claudin-18 deficiency is associated with airway epithelial barrier dysfunction and asthma. J Allergy Clin Immunol. 2017 01; 139(1):72-81.e1.
PMID: 27215490.
View in: PubMed Mentions: 23 Fields: Translation: HumansAnimalsCells
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98 Common genetic polymorphisms in the ST2 gene locus are associated with impaired soluble ST2 expression in the airway epithelium. Cytokine. 2013 Sep 1; 63(3):266.
Erin D. Gordon, Cydney Urbanek, Shaopeng Yuan, Prescott Woodruff, John V. Fahy, Max A. Seibold. .
View in: Publisher Site Mentions:
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99 IL-33 splice variants are critical to its regulated secretion from airway epithelial cells. Cytokine. 2013 Sep 1; 63(3):266.
Erin D. Gordon, Marrah Lachowicz-Scroggins, Cydney Urbanek, Max A. Seibold, John V. Fahy. .
View in: Publisher Site Mentions:
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A protective role for periostin and TGF-ß in IgE-mediated allergy and airway hyperresponsiveness. Clin Exp Allergy. 2012 Jan; 42(1):144-55.
PMID: 22093101.
View in: PubMed Mentions: 31 Fields: Translation: Animals
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Management of chronic obstructive pulmonary disease: moving beyond the asthma algorithm. J Allergy Clin Immunol. 2009 Nov; 124(5):873-80; quiz 881-2.
Gordon E, Lazarus SC. PMID: 19895979.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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(R)-albuterol decreases immune responses: role of activated T cells. Respir Res. 2008 Jan 14; 9:3.
Ferrada MA, Gordon EL, Jen KY, He HZ, Lu X, Barone LM, Amirifeli S, Perkins DL, Finn PW. PMID: 18194569.
View in: PubMed Mentions: 5 Fields: Translation: AnimalsCells
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Year | Publications |
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2008 | 1 | 2009 | 1 | 2011 | 1 | 2013 | 2 | 2016 | 4 | 2017 | 1 | 2018 | 2 | 2019 | 1 | 2020 | 1 |
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