Wilfred Raymond

Title(s)Specialist, Cardiovascular Research Inst
SchoolSchool of Medicine
Address513 Parnassus Avenue, HSE, #1350
San Francisco CA 94143
Phone415-476-0752
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Peroxidase-mediated mucin cross-linking drives pathologic mucus gel formation in IL-13-stimulated airway epithelial cells. JCI Insight. 2024 Jun 18; 9(15). Liegeois MA, Braunreuther M, Charbit AR, Raymond WW, Tang M, Woodruff PG, Christenson SA, Castro M, Erzurum SC, Israel E, Jarjour NN, Levy BD, Moore WC, Wenzel SE, Fuller GG, Fahy JV. PMID: 38889046; PMCID: PMC11383604.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Utility of eosinophil peroxidase as a biomarker of eosinophilic inflammation in asthma. J Allergy Clin Immunol. 2024 Sep; 154(3):580-591.e6. Tang M, Charbit AR, Johansson MW, Jarjour NN, Denlinger LC, Raymond WW, Peters MC, Dunican EM, Castro M, Sumino K, Erzurum SC, Comhair SA, Moore WC, Levy BD, Israel E, Phipatanakul W, Phillips BR, Mauger DT, Bleecker ER, Wenzel SE, Fajt ML, Woodruff PG, Hastie AT, Fahy JV, National Heart Lung and Blood Institute Severe Asthma Research Program. PMID: 38663815.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. A novel DNase assay reveals low DNase activity in severe asthma. Am J Physiol Lung Cell Mol Physiol. 2024 Jun 01; 326(6):L796-L804. Charbit AR, Liegeois MA, Raymond WW, Comhair SAA, Johansson MW, Hastie AT, Bleecker ER, Fajt M, Castro M, Sumino K, Erzurum SC, Israel E, Jarjour NN, Mauger DT, Moore WC, Wenzel SE, Woodruff PG, Levy BD, Tang MC, Fahy JV. PMID: 38651338; PMCID: PMC11380938.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. MICB Genomic Variant Is Associated with NKG2D-mediated Acute Lung Injury and Death. Am J Respir Crit Care Med. 2024 01 01; 209(1):70-82. Aguilar OA, Qualls AE, Gonzalez-Hinojosa MDR, Obeidalla S, Kerchberger VE, Tsao T, Singer JP, Looney MR, Raymond W, Hays SR, Golden JA, Kukreja J, Shaver CM, Ware LB, Christie J, Diamond JM, Lanier LL, Greenland JR, Calabrese DR. PMID: 37878820; PMCID: PMC10870895.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. A novel thiol-saccharide mucolytic for the treatment of muco-obstructive lung diseases. Eur Respir J. 2023 05; 61(5). Addante A, Raymond W, Gitlin I, Charbit A, Orain X, Scheffler AW, Kuppe A, Duerr J, Daniltchenko M, Drescher M, Graeber SY, Healy AM, Oscarson S, Fahy JV, Mall MA. PMID: 37080569; PMCID: PMC10209473.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    6. Exploring antiviral and anti-inflammatory effects of thiol drugs in COVID-19. Am J Physiol Lung Cell Mol Physiol. 2022 09 01; 323(3):L372-L389. Khanna K, Raymond WW, Jin J, Charbit AR, Gitlin I, Tang M, Werts AD, Barrett EG, Cox JM, Birch SM, Martinelli R, Sperber HS, Franz S, Duff T, Hoffmann M, Healy AM, Oscarson S, Pöhlmann S, Pillai SK, Simmons G, Fahy JV. PMID: 35762590; PMCID: PMC9448286.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    7. Thiol drugs decrease SARS-CoV-2 lung injury in vivo and disrupt SARS-CoV-2 spike complex binding to ACE2 in vitro. bioRxiv. 2021 Nov 11. Khanna K, Raymond W, Jin J, Charbit AR, Gitlin I, Tang M, Werts AD, Barrett EG, Cox JM, Birch SM, Martinelli R, Sperber HS, Franz S, Pillai S, Healy AM, Duff T, Oscarson S, Hoffmann M, Pöhlmann S, Simmons G, Fahy JV. PMID: 33330868; PMCID: PMC7743076.
      View in: PubMed   Mentions:
    8. Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma. Am J Respir Crit Care Med. 2019 05 01; 199(9):1076-1085. Lachowicz-Scroggins ME, Dunican EM, Charbit AR, Raymond W, Looney MR, Peters MC, Gordon ED, Woodruff PG, Lefrançais E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Hastie AT, Bleecker ER, Fajt ML, Wenzel SE, Israel E, Levy BD, Fahy JV. PMID: 30888839; PMCID: PMC6515873.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansCells
    9. Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. J Clin Invest. 2018 03 01; 128(3):997-1009. Dunican EM, Elicker BM, Gierada DS, Nagle SK, Schiebler ML, Newell JD, Raymond WW, Lachowicz-Scroggins ME, Di Maio S, Hoffman EA, Castro M, Fain SB, Jarjour NN, Israel E, Levy BD, Erzurum SC, Wenzel SE, Meyers DA, Bleecker ER, Phillips BR, Mauger DT, Gordon ED, Woodruff PG, Peters MC, Fahy JV, National Heart Lung and Blood Institute (NHLBI) Severe Asthma Research Program (SARP). PMID: 29400693; PMCID: PMC5824874.
      View in: PubMed   Mentions: 172     Fields:    Translation:Humans
    10. Divergent Inhibitor Susceptibility among Airway Lumen-Accessible Tryptic Proteases. PLoS One. 2015; 10(10):e0141169. Nimishakavi S, Raymond WW, Gruenert DC, Caughey GH. PMID: 26485396; PMCID: PMC4612780.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    11. Regulation of hepatocyte growth factor in mice with pneumonia by peptidases and trans-alveolar flux. PLoS One. 2015; 10(5):e0125797. Raymond WW, Xu X, Nimishakavi S, Le C, McDonald DM, Caughey GH. PMID: 25938594; PMCID: PMC4418689.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    12. Mutational tail loss is an evolutionary mechanism for liberating marapsins and other type I serine proteases from transmembrane anchors. J Biol Chem. 2013 Apr 12; 288(15):10588-98. Raman K, Trivedi NN, Raymond WW, Ganesan R, Kirchhofer D, Verghese GM, Craik CS, Schneider EL, Nimishakavi S, Caughey GH. PMID: 23447538; PMCID: PMC3624440.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    13. Activity and inhibition of prostasin and matriptase on apical and basolateral surfaces of human airway epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2012 Jul; 303(2):L97-106. Nimishakavi S, Besprozvannaya M, Raymond WW, Craik CS, Gruenert DC, Caughey GH. PMID: 22582115; PMCID: PMC3404626.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    14. The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells. J Clin Invest. 2012 Feb; 122(2):748-58. Sugimoto K, Kudo M, Sundaram A, Ren X, Huang K, Bernstein X, Wang Y, Raymond WW, Erle DJ, Abrink M, Caughey GH, Huang X, Sheppard D. PMID: 22232213; PMCID: PMC3266785.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    15. Secreted osteopontin is highly polymerized in human airways and fragmented in asthmatic airway secretions. PLoS One. 2011; 6(10):e25678. Arjomandi M, Frelinger J, Donde A, Wong H, Yellamilli A, Raymond W. PMID: 22031818; PMCID: PMC3198733.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    16. How immune peptidases change specificity: cathepsin G gained tryptic function but lost efficiency during primate evolution. J Immunol. 2010 Nov 01; 185(9):5360-8. Raymond WW, Trivedi NN, Makarova A, Ray M, Craik CS, Caughey GH. PMID: 20889553; PMCID: PMC3954857.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    17. Ex vivo sputum analysis reveals impairment of protease-dependent mucus degradation by plasma proteins in acute asthma. Am J Respir Crit Care Med. 2009 Aug 01; 180(3):203-10. Innes AL, Carrington SD, Thornton DJ, Kirkham S, Rousseau K, Dougherty RH, Raymond WW, Caughey GH, Muller SJ, Fahy JV. PMID: 19423716; PMCID: PMC2724713.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    18. Alpha 2-macroglobulin capture allows detection of mast cell chymase in serum and creates a reservoir of angiotensin II-generating activity. J Immunol. 2009 May 01; 182(9):5770-7. Raymond WW, Su S, Makarova A, Wilson TM, Carter MC, Metcalfe DD, Caughey GH. PMID: 19380825; PMCID: PMC2756746.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    19. Guinea pig chymase is leucine-specific: a novel example of functional plasticity in the chymase/granzyme family of serine peptidases. J Biol Chem. 2008 May 16; 283(20):13943-51. Caughey GH, Beauchamp J, Schlatter D, Raymond WW, Trivedi NN, Banner D, Mauser H, Fingerle J. PMID: 18353771; PMCID: PMC2376239.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    20. Chimerism, point mutation, and truncation dramatically transformed mast cell delta-tryptases during primate evolution. J Allergy Clin Immunol. 2008 May; 121(5):1262-8. Trivedi NN, Raymond WW, Caughey GH. PMID: 18325577.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    21. Mast cell and neutrophil peptidases attack an inactivation segment in hepatocyte growth factor to generate NK4-like antagonists. J Biol Chem. 2006 Jan 20; 281(3):1489-94. Raymond WW, Cruz AC, Caughey GH. PMID: 16303761; PMCID: PMC2271111.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    22. Mastin is a gelatinolytic mast cell peptidase resembling a mini-proteasome. Arch Biochem Biophys. 2005 Mar 15; 435(2):311-22. Raymond WW, Sommerhoff CP, Caughey GH. PMID: 15708374.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    23. Matrix metalloproteinase-2 and -9 expression increases in Mycoplasma-infected airways but is not required for microvascular remodeling. Am J Physiol Lung Cell Mol Physiol. 2004 Aug; 287(2):L307-17. Baluk P, Raymond WW, Ator E, Coussens LM, McDonald DM, Caughey GH. PMID: 15075248.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    24. Albumin is a substrate of human chymase. Prediction by combinatorial peptide screening and development of a selective inhibitor based on the albumin cleavage site. J Biol Chem. 2003 Sep 05; 278(36):34517-24. Raymond WW, Ruggles SW, Craik CS, Caughey GH. PMID: 12815038.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    25. Structure of human pro-chymase: a model for the activating transition of granule-associated proteases. Biochemistry. 2003 Mar 11; 42(9):2616-24. Reiling KK, Krucinski J, Miercke LJ, Raymond WW, Caughey GH, Stroud RM. PMID: 12614156.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    26. Lys40 but not Arg143 influences selectivity of angiotensin conversion by human alpha-chymase. Biochim Biophys Acta. 2002 Apr 29; 1596(2):346-56. Muilenburg DJ, Raymond WW, Wolters PJ, Caughey GH. PMID: 12007614.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
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