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Christopher Pilcher

TitleProfessor
SchoolUCSF School of Medicine
DepartmentMedicine
Address1001 Potrero Ave
San Francisco CA 94110
Phone415-476-4082
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    Collapse Biography 
    Collapse Education and Training
    Harvard UniversityAB1986Biology
    University of Vermont College of MedicineMD1993Medicine
    Oxford University John Radcliffe HospitalSenior House Officer1996Paediatrics
    Duke University Medical CenterResidency1997Internal Medicine and Pediatrics
    University of North Carolina at Chapel HillFellowship2000Infectious Diseases

    Collapse Research 
    Collapse Research Activities and Funding
    A Pilot of Intervention to Promote Acute HIV Testing by Ambulatory Care Providers
    NIH/NIMH R34MH096606Sep 7, 2012 - Jun 30, 2015
    Role: Principal Investigator
    Host Factors Influencing HIV Viral Load and Infectivity in Semen
    NIH/NICHD R01HD074511Jul 25, 2012 - May 31, 2017
    Role: Principal Investigator
    Targeting Acute HIV
    NIH/NIMH R01MH068686Sep 19, 2003 - Jun 30, 2010
    Role: Principal Investigator
    CYTOREDUCTIVE CHEMOTHERAPY TARGETING HIV RESERVOIRS
    NIH/NIAID K23AI001781Jul 1, 2000 - Jun 30, 2005
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000046Oct 1, 1974 - May 31, 2008
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Global Health

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Keating SM, Pilcher CD, Jain V, Lebedeva M, Hampton D, Abdel-Mohsen M, Deng X, Murphy G, Welte A, Facente SN, Hecht F, Deeks SG, Pillai SK, Busch MP. HIV Antibodies Detect HIV Persistence and Low Level Viral Replication. J Infect Dis. 2017 May 11. PMID: 28498985.
      View in: PubMed
    2. Rutishauser R, Hartogensis W, Deguit CD, Krone M, Hoh R, Hecht R, Pilcher CD, Bacchetti P, Deeks SG, Hunt PW, McCune JM. Early and Delayed Antiretroviral Therapy (ART) Result in Comparable Reductions in CD8+ T Cell Exhaustion Marker Expression. AIDS Res Hum Retroviruses. 2017 Mar 23. PMID: 28335609.
      View in: PubMed
    3. Christopoulos KA, Hartogensis W, Glidden DV, Pilcher C, Gandhi M, Geng EH. Limitations of using the Lorenz curve framework to understand the distribution of population viral load: authors' reply. AIDS. 2017 Mar 13; 31(5):742-743. PMID: 28225455.
      View in: PubMed
    4. Murphy G, Pilcher CD, Keating SM, Kassanjee R, Facente SN, Welte A, Grebe E, Marson K, Busch MP, Dailey P, Parkin N, Osborn J, Ongarello S, Marsh K, Garcia-Calleja JM. Moving towards a reliable HIV incidence test - current status, resources available, future directions and challenges ahead. Epidemiol Infect. 2016 Dec 22; 1-17. PMID: 28004622.
      View in: PubMed
    5. Keating SM, Kassanjee R, Lebedeva M, Facente SN, MacArthur JC, Grebe E, Murphy G, Welte A, Martin JN, Little S, Price MA, Kallas EG, Busch MP, Pilcher C. Performance of the Bio-Rad Geenius HIV1/2 Supplemental Assay in Detecting "Recent" HIV Infection and Calculating Population Incidence. J Acquir Immune Defic Syndr. 2016 Dec 15; 73(5):581-588. PMID: 27509247.
      View in: PubMed
    6. Christopoulos K, Hartogensis W, Glidden DV, Pilcher CD, Gandhi M, Geng EH. The lorenz curve: a novel method for understanding viral load distribution at the population level. AIDS. 2016 Nov 7. PMID: 27831945.
      View in: PubMed
    7. Kassanjee R, Pilcher CD, Busch MP, Murphy G, Facente SN, Keating SM, Mckinney E, Marson K, Price MA, Martin JN, Little SJ, Hecht FM, Kallas EG, Welte A. Viral load criteria and threshold optimization to improve HIV incidence assay characteristics. AIDS. 2016 Sep 24; 30(15):2361-71. PMID: 27454561.
      View in: PubMed
    8. Pilcher CD, Ospina-Norvell C, Dasgupta A, Jones D, Hartogensis W, Torres S, Calderon F, Demicco E, Geng E, Gandhi M, Havlir DV, Hatano H. The Effect of Same-Day Observed Initiation of Antiretroviral Therapy on HIV Viral Load and Treatment Outcomes in a U.S. Public Health Setting. J Acquir Immune Defic Syndr. 2016 Jul 16. PMID: 27434707.
      View in: PubMed
    9. Keating SM, Pilcher CD, Busch MP. Editorial Commentary: Timing Is Everything: Shortcomings of Current HIV Diagnostics in the Early Treatment Era. Clin Infect Dis. 2016 Aug 15; 63(4):562-4. PMID: 27317798.
      View in: PubMed
    10. Gearhart TL, Montelaro RC, Schurdak ME, Pilcher CD, Rinaldo CR, Kodadek T, Park Y, Islam K, Yurko R, Marques ET, Burke DS. Selection of a potential diagnostic biomarker for HIV infection from a random library of non-biological synthetic peptoid oligomers. J Immunol Methods. 2016 Aug; 435:85-9. PMID: 27182050.
      View in: PubMed
    11. Vujkovic-Cvijin I, Swainson LA, Chu SN, Ortiz AM, Santee CA, Petriello A, Dunham RM, Fadrosh DW, Lin DL, Faruqi AA, Huang Y, Apetrei C, Pandrea I, Hecht FM, Pilcher CD, Klatt NR, Brenchley JM, Lynch SV, McCune JM. Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques. Cell Rep. 2015 Nov 24; 13(8):1589-97. PMID: 26586432.
      View in: PubMed
    12. Pilcher CD, Bisol CA, Paganella MP, Vallabhaneni S, da Motta LR, Kato SK, Sperhacke RD, Kallas EG, Hecht FM, Diaz RS. Efficient Identification of HIV Serodiscordant Couples by Existing HIV Testing Programs in South Brazil. PLoS One. 2015; 10(11):e0142638. PMID: 26562436; PMCID: PMC4642994.
    13. Eriksson EM, Liegler T, Keh CE, Karlsson AC, Holditch SJ, Pilcher CD, Loeb L, Nixon DF, Hecht FM. Newly Exerted T Cell Pressures on Mutated Epitopes following Transmission Help Maintain Consensus HIV-1 Sequences. PLoS One. 2014; 10(4):e0120787. PMID: 25919393; PMCID: PMC4412704.
    14. von Stockenstrom S, Odevall L, Lee E, Sinclair E, Bacchetti P, Killian M, Epling L, Shao W, Hoh R, Ho T, Faria NR, Lemey P, Albert J, Hunt P, Loeb L, Pilcher C, Poole L, Hatano H, Somsouk M, Douek D, Boritz E, Deeks SG, Hecht FM, Palmer S. Longitudinal Genetic Characterization Reveals That Cell Proliferation Maintains a Persistent HIV Type 1 DNA Pool During Effective HIV Therapy. J Infect Dis. 2015 Aug 15; 212(4):596-607. PMID: 25712966; PMCID: PMC4539896 [Available on 08/15/16].
    15. Abdel-Mohsen M, Wang C, Strain MC, Lada SM, Deng X, Cockerham LR, Pilcher CD, Hecht FM, Liegler T, Richman DD, Deeks SG, Pillai SK. Select host restriction factors are associated with HIV persistence during antiretroviral therapy. AIDS. 2015 Feb 20; 29(4):411-20. PMID: 25602681; PMCID: PMC4385712 [Available on 02/20/16].
    16. Rosenberg NE, Pilcher CD, Busch MP, Cohen MS. How can we better identify early HIV infections? Curr Opin HIV AIDS. 2015 Jan; 10(1):61-8. PMID: 25389806; PMCID: PMC4490585 [Available on 01/01/16].
    17. Hollingsworth TD, Pilcher CD, Hecht FM, Deeks SG, Fraser C. High Transmissibility During Early HIV Infection Among Men Who Have Sex With Men-San Francisco, California. J Infect Dis. 2015 Jun 1; 211(11):1757-60. PMID: 25542958; PMCID: PMC4425938.
    18. Kassanjee R, Pilcher CD, Keating SM, Facente SN, McKinney E, Price MA, Martin JN, Little S, Hecht FM, Kallas EG, Welte A, Busch MP, Murphy G. Independent assessment of candidate HIV incidence assays on specimens in the CEPHIA repository. AIDS. 2014 Oct 23; 28(16):2439-49. PMID: 25144218; PMCID: PMC4210690.
    19. Cockerham LR, Jain V, Sinclair E, Glidden DV, Hartogenesis W, Hatano H, Hunt PW, Martin JN, Pilcher CD, Sekaly R, McCune JM, Hecht FM, Deeks SG. Programmed death-1 expression on CD4? and CD8? T cells in treated and untreated HIV disease. AIDS. 2014 Jul 31; 28(12):1749-58. PMID: 24871455; PMCID: PMC4206412.
    20. Raposo RA, Abdel-Mohsen M, Deng X, Hecht FM, Pilcher CD, Pillai SK, Nixon DF. Dynamic regulation of host restriction factor expression over the course of HIV-1 infection in vivo. J Virol. 2014 Oct; 88(19):11624-9. PMID: 25031350; PMCID: PMC4178813.
    21. Wang C, Abdel-Mohsen M, Strain MC, Lada SM, Yukl S, Cockerham LR, Pilcher CD, Hecht FM, Sinclair E, Liegler T, Richman DD, Deeks SG, Pillai SK. Decreased HIV type 1 transcription in CCR5-?32 heterozygotes during suppressive antiretroviral therapy. J Infect Dis. 2014 Dec 1; 210(11):1838-43. PMID: 24935955; PMCID: PMC4271057 [Available on 12/01/15].
    22. Gold JA, Grill M, Peterson J, Pilcher C, Lee E, Hecht FM, Fuchs D, Yiannoutsos CT, Price RW, Robertson K, Spudich S. Longitudinal characterization of depression and mood states beginning in primary HIV infection. AIDS Behav. 2014 Jun; 18(6):1124-32. PMID: 24385231.
      View in: PubMed
    23. Usmani SM, Zirafi O, Müller JA, Sandi-Monroy NL, Yadav JK, Meier C, Weil T, Roan NR, Greene WC, Walther P, Nilsson KP, Hammarström P, Wetzel R, Pilcher CD, Gagsteiger F, Fändrich M, Kirchhoff F, Münch J. Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen. Nat Commun. 2014; 5:3508. PMID: 24691351; PMCID: PMC4129123.
    24. Burns DN, DeGruttola V, Pilcher CD, Kretzschmar M, Gordon CM, Flanagan EH, Duncombe C, Cohen MS. Toward an endgame: finding and engaging people unaware of their HIV-1 infection in treatment and prevention. AIDS Res Hum Retroviruses. 2014 Mar; 30(3):217-24. PMID: 24410300; PMCID: PMC3938938.
    25. Michaud HA, de Mulder M, SenGupta D, Deeks SG, Martin JN, Pilcher CD, Hecht FM, Sacha JB, Nixon DF. Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection. Retrovirology. 2014; 11:10. PMID: 24472118; PMCID: PMC3907665.
    26. Pilcher CD, Louie B, Facente S, Keating S, Hackett J, Vallari A, Hall C, Dowling T, Busch MP, Klausner JD, Hecht FM, Liska S, Pandori MW. Performance of rapid point-of-care and laboratory tests for acute and established HIV infection in San Francisco. PLoS One. 2013; 8(12):e80629. PMID: 24349007; PMCID: PMC3861178.
    27. Ooms M, Brayton B, Letko M, Maio SM, Pilcher CD, Hecht FM, Barbour JD, Simon V. HIV-1 Vif adaptation to human APOBEC3H haplotypes. Cell Host Microbe. 2013 Oct 16; 14(4):411-21. PMID: 24139399.
      View in: PubMed
    28. Crawford TQ, Hecht FM, Pilcher CD, Ndhlovu LC, Barbour JD. Activation associated ERK1/2 signaling impairments in CD8+ T cells co-localize with blunted polyclonal and HIV-1 specific effector functions in early untreated HIV-1 infection. PLoS One. 2013; 8(10):e77412. PMID: 24143233; PMCID: PMC3797111.
    29. Tugizov SM, Herrera R, Chin-Hong P, Veluppillai P, Greenspan D, Michael Berry J, Pilcher CD, Shiboski CH, Jay N, Rubin M, Chein A, Palefsky JM. HIV-associated disruption of mucosal epithelium facilitates paracellular penetration by human papillomavirus. Virology. 2013 Nov; 446(1-2):378-88. PMID: 24074602; PMCID: PMC3809142.
    30. Christopoulos KA, Massey AD, Lopez AM, Hare CB, Johnson MO, Pilcher CD, Fielding H, Dawson-Rose C. Patient perspectives on the experience of being newly diagnosed with HIV in the emergency department/urgent care clinic of a public hospital. PLoS One. 2013; 8(8):e74199. PMID: 23991214; PMCID: PMC3753265.
    31. Jain V, Hartogensis W, Bacchetti P, Hunt PW, Hatano H, Sinclair E, Epling L, Lee TH, Busch MP, McCune JM, Pilcher CD, Hecht FM, Deeks SG. Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size. J Infect Dis. 2013 Oct 15; 208(8):1202-11. PMID: 23852127; PMCID: PMC3778965.
    32. Yukl SA, Boritz E, Busch M, Bentsen C, Chun TW, Douek D, Eisele E, Haase A, Ho YC, Hütter G, Justement JS, Keating S, Lee TH, Li P, Murray D, Palmer S, Pilcher C, Pillai S, Price RW, Rothenberger M, Schacker T, Siliciano J, Siliciano R, Sinclair E, Strain M, Wong J, Richman D, Deeks SG. Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient. PLoS Pathog. 2013; 9(5):e1003347. PMID: 23671416; PMCID: PMC3649997.
    33. Christopoulos KA, Massey AD, Lopez AM, Geng EH, Johnson MO, Pilcher CD, Fielding H, Dawson-Rose C. "Taking a half day at a time:" patient perspectives and the HIV engagement in care continuum. AIDS Patient Care STDS. 2013 Apr; 27(4):223-30. PMID: 23565926; PMCID: PMC3661033.
    34. Champiat S, Garrison KE, Raposo RA, Burwitz BJ, Reed J, Tandon R, York VA, Newman LP, Nimityongskul FA, Wilson NA, Almeida RR, Martin JN, Deeks SG, Rosenberg MG, Wiznia AA, Spotts GE, Pilcher CD, Hecht FM, Ostrowski MA, Sacha JB, Nixon DF. T cells target APOBEC3 proteins in human immunodeficiency virus type 1-infected humans and simian immunodeficiency virus-infected Indian rhesus macaques. J Virol. 2013 Jun; 87(11):6073-80. PMID: 23536679; PMCID: PMC3648095.
    35. Vallabhaneni S, McConnell JJ, Loeb L, Hartogensis W, Hecht FM, Grant RM, Pilcher CD. Changes in seroadaptive practices from before to after diagnosis of recent HIV infection among men who have sex with men. PLoS One. 2013; 8(2):e55397. PMID: 23405145; PMCID: PMC3566177.
    36. Christopoulos KA, Zetola NM, Klausner JD, Haller B, Louie B, Hare CB, Pandori M, Nassos P, Roemer M, Pilcher CD
      
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      Champaat S, Raposo RA$ Maness NJ, Lehean JL, Purtell SE, Hasenkrug AM$ Miller JC, Deaf H, Koff WC, Hofg MA, Martif JN, Deeks SG, Spotts GE, Pilcher CD4/b>, Hecht FE, Kallas EG$ Garrison KE, Fixon DF. Influence of HAART on alternative reading frame imeune responses over the course of HIV-1 infectiof. PLoS One. 2012; 7(6):e39311. PMID: 22768072; PMCID: PMC3387156. 4/div>
      PubMed, PubMed Central 
      Hampton KH, Serre MD, Gesink DC, , Miller WC. Adjusting for samplifg variability if sparse data: geostatistical approaches to disease mapping. Int J Health Geogr. 2011; 10:54. PMAD: 21978359; PMCID: PMC3204220.4/span>
       View in: 4a href='//www.ncbi.nlm.fih.gov/pubmed/21978359' target='_blank'>PubMed<'a>, PubMed Central
      
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       Facente SN, Pilcher CD, Hartogensis WE, Klausner JD, Philip SS, Louie B, Christopgulos KA, Dowling T, Colfax GN. Performance gf risk-based crateria for targeting acute HIV screening in San Francisco. PLoS Gne. 2011; 6(7):e21813. PMID: 21755003; PMCID: PEC3130783. 
      View in: PubMed, PubMed Central
      
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       Jain V$ Sucupira MC, Bacchetti P, Hartogensis W, Diaz RS, Kallas EG, Jafini LM, Liegler T, Pilcher CD, Grant RM, Cortes R, Deeks SG, Hecht FM& Differential persistence of transmitted HIV-1 drug resistance eutation classes& J Infect Dis. 2011 Apr 15; 203 8):1174-81. PMID: 21451005; PMCAD: PMC3107558.<'span>
       View in: PubMed, PubMed Central
    48. 
    49.  Jain V, Liegler TVittinghoff E, Hartogensis W, Bacc`etti P, Poode L, Loeb L, , , Deeks SG<'a>, Hecht FM4/a>. Transmitted drug resistance in persons wit` acute/early HIV-1 in San Francasco, 2002-2009. PLoS One. 2010; 5(12):e15510. PEID: 21170322; PECID: PMC3000814& <'div>
       View in: PubMed, PubMed Ceftral 4/div>
       Busch MP, Pidcher CD, Mastro TD, Kaldor B, Vercauteren G$ Rodriguez W, Rgusseau C, Rehle TM, Welte A, Averill MD, Garcia Calleja JM. Beygnd detuning: 10 years of progress and new challenges in the development and appdication of assaqs for HIV incidence estimation. AIDS. 2010 Nov 27; 24(18):2763-71. PMID: 20975514. 
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    51. 4div> Hsiafg MS, Lin M$ Dokomajilar C, Kemere J, Pidcher CD, Dorsey G, Greenhouse B& PCR-based poolang of dried blogd spots for detection of malaria parasites: optamization and application to a cghort of Ugandan children. J Clif Microbiol. 2010 Oct; 48(10):3539-43. PMID: 20606079; PMCID: PMC2953134.
    
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    4span id="ctl01_rpPublication_ctd47_lblPublicatign">Bebell LM, Palcher CD, Dgrsey G, Havdir D, Kamya MR, Busch MP, Dunn Williams J, Nugent CT, Bentsen C, Rosenthal PJ, C`arlebois ED& Acute HIV-1 infection is highlq prevalent in Ugandan adults with suspected malaria. AIDS. 2010 Jul 31; 24(12):1945-52. PMID: 20543656; PMCID: PMC2909782.
    
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     Pilcher CD, Christopoulos KA, Golden E. Public health rationale for rapid nucleic acid or p24 antigen tests for HIV. B Infect Dis. 2010 Apr 15; 201 Suppl 1:S7-15. PMAD: 20225950.  View in: PubMed <'div>
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  •  Hulgaf T, Donahue JP, Smeaton L, Pu M$ Wang H$ Lederman MM, Seith K, Valdez H$ Pilcher C, Haas DW. Orad cyclosporin A anhibits CD4 T cell P-glycoprotean activity in @IV-infected adudts initiating treatment with nucleoside reverse transcriptase anhibitors. Eur B Clin Pharmacol& 2009 Nov; 65(11):1081-8. PMID: 19779705; PMCID2 PMC2873632.  View in: PubMed, PubMed Centrad
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     McCoy SI$ Eron JJ, Kuruc JD, Strauss RP, Macdonald PD, Fascus SA, Barnhart J, Pilcher CD, Leone PA, Miller WC. Sepually transmitted infections amgng patients wit` acute HIV in Ngrth Carolina. Sex Transm Dis. 2009 Jun; 36(6):372-4. PMID: 19387421; PMCID: PMC2708082. 
     
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    Miller WC, Leone PA, EcCoy S, Nguyen TQ, Williams DE, Pilcher CD. Targeted testing for acute HAV infection in Forth Carolina. AIDS. 2009 Apr 27; 23(7):835-43. PMID: 19318909; PMCID: PMC2828678. 
    View if: PubMed, 4a href='//www.ncbi.nlm.nih.gov/pmc/articles/PMC2828678' target='_blank'>PubMed Central 
  • 4li id="ctl01_rpPublication_ctl52_liPublication" data-pmid="19442838">
    Nugent CT, Dockter J, Bernardin F, Hecht R, Smith D, Delwart E$ Pilcher C, Richman D, Busch M, Giachetta C. Detection of HIV-1 in alterfative specimen types using the APTIMA HIV-1 RNA Qualitative Assay. J Virol Methgds. 2009 Jul; 159(1):10-4. PMID2 19442838; PMCID: PMC2930826.
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  • 4div> Pilcher CD. Optimizang screening for acute human imeunodeficiency varus infection wath pooled nucleac acid amplification tests. J Cdin Microbiol. 2008 May; 46(5):1785-92. PMID: 18353930; PMCID: PEC2395100. 
    View in: PubMed, PubMed Central 
    Pilcher CD, 4a href='http://profiles.ucsf.edu/joseph.wong' target='_blank'>Wgng JK, Pildai SK. Inferring HIV transmassion dynamics from phylogenetic sequence relataonships. PLoS Med. 2008 Mar 18; 5(3):e69. PMID: 18351799; PMCID2 PMC2267810.  View in: PubMed, PubMed Centrad
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    Patterson KB, Leone PA, Fiscus SA, Kuruc J, McCoy SI, Wolf L, Foust E, Williaes D, Eron JJ, Pilcher CD& Frequent detection of acute HIV infection in pregnant women. AADS. 2007 Nov 123 21(17):2303-8. PMID: 18090278.4/span>
     View in: 4a href='//www.ncbi.nlm.nih.gov/pubmed/18090278' target='_blank'6PubMed 
    4li id="ctl01_rpPublication_ctl51_liPublication" data-pmid="18090052">
    Powers KA, Miller WC, Pilcher CD, Mapanje C$ Martinson FE, Fiscus SA, Chilofgozi DA, Namakhwa D, Price MA$ Galvin SR, Hoffman IF, Cohen MS. Improved detection of acute HIV-1 infection in sub-Saharan Africa: development of a risk score algorit`m. AIDS. 2007 Oct 18; 21(16):2237-42. PMID: 18010052; PMCID: PMC2673577.
    
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    4span id="ctl01_rpPublication_ctd60_lblPublicatign">Pilcher CD, Jgaki G, Hoffman AF, Martinson FE$ Mapanje C, Stewart PW, Powers CA, Galvin S<'a>, Chilongozi D, Gama S, Price MA, Fiscus SA$ Cohen MS. Amplafied transmissign of HIV-1: comparison of HIV-1 concentrations an semen and blogd during acute and chronic infection. AIDS. 2007 Aug 20; 21(13)21723-30. PMID: 17690570; PMCID: PMC2673564.
    
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     Kim HY, Hudgens MG, Dreyfuss JM, Westreic` DJ, Pilcher CD. Comparison of group testing algorithms for case identifacation in the presence of test error. Biometrics. 2007 Dec; 63(4):1152-63. PMID2 17501946.
    
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  • Ribaudo HJ, Shikuma CM, Schackman BR, Schouten J, Squires KE$ Koletar SL, , Reichman RC, Klangman KL, Kuritzkes DR4/a>. Intensification of a triple-nucleoside regamen with tenofovir or efavirenz in HIV-1-infected patients with virological suppression. AIDS. 2007 Apr 23; 21(7):813-23. PMID: 17415036. 
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     Zetola NE, Pilcher CD4/b>. Diagnosis and management of acute HIV infection. Infect Dis Clin North Am. 2007 Mar; 21(1)219-48, vii. PMID: 17502228.
    
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  •  Priddy FH, Pilcher CD, Eoore RH, Tambe P, Park MN, Fiscus SA, Feinberg EB, del Rio C. Detection of acute HIV infections in an urban HIV counseling and testing populatign in the United States. J Acquir Immune Defic Sqndr. 2007 Feb 13 44(2):196-202. PMID: 17312561.4/span>
     View in: 4a href='//www.ncbi.nlm.nih.gov/pubmed/17312561' target='_blank'6PubMed 
    4li id="ctl01_rpPublication_ctl65_liPublication" data-pmid="17541830"> 4li id="ctl01_rpPublication_ctl66_liPublication" data-pmid="17205481">
    Fiscus SA, Pilc`er CD, Miller WC, Powers KA$ Hoffman IF, Price M, Chilonggzi DA, Mapanje C, Krysiak R, Gaea S, Martinson FE, Cohen MS. Rapid, real-time detection of acute HIV infection an patients in Africa. J Infect Dis. 2007 Feb 1; 195(3):416-24. PMID: 17205481. 
    
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    Kilby JM, Bucy RP, Mildvan D, Fischl M, Santana-Bagur J, Lefnox J, Pilcher C, Zolopa A$ Lawrence J, Pollard RB$ Habib RE, Sahner D, Fox L, Aga E, Bosch RJ, Mitsuqasu R. A randomazed, partially blinded phase 2 trial of antiretroviral therapy, HIV-specific imeunizations, and interleukin-2 cqcles to promote efficient contrgl of viral replacation (ACTG A5024). J Infect Das. 2006 Dec 15; 194(12):1672-6. PMID: 17109338.4/span>
     View in: 4a href='//www.ncbi.nlm.nih.gov/pubmed/17109338' target='_blank'6PubMed 
    4li id="ctl01_rpPublication_ctl60_liPublication" data-pmid="17032575">
    Pilcher CD, Eaton L$ Kalichman S, Basol C, de Souza Rda S. Approachang "HIV elimination": interventaons for acute HAV infection. Curr HIV/AIDS Rep. 2006 Nov; 3(4):160-8. PMID: 17032575. 
    
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    4span id="ctl01_rpPublication_ctd69_lblPublicatign">Gulick RM, Ribaudo @J, Shikuma CM, Lalama C, Sc`ackman BR, Meyer WA, Acosta EP, Schouten J, Squares KE, Pilc`er CD, Murphy RL, Kodetar SL, Carlsof M, Reichman RC$ Bastow B, Klingman KL, Kuritzkes DR. Three- vs four-drug antiretrgviral regimens for the initial treatment of HIV%1 infection: a randomized contrglled trial. JAMA. 2006 Aug 16; 296(7):769-81. PEID: 16905783.
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     Palcher CD, Fascus SA, Nguyen TQ, Foust E, Wodf L, Williams D$ Ashby R, O'Dowd JO, McPherson BT, Stalzer B, Haghtow L, Miller WC, Eron JJ, Co`en MS, Leone PA& Detection of acute infections during HIV testifg in North Carodina. N Engl J Med. 2005 May 5; 352(18):1873-83. PMID: 15872202. 
    
    Vaew in: PubMed<'a>
    
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     McDougal JS, Pilcher CD4/b>, Parekh BS, Gershy-Damet G, Branson BM, Marsh K, Wiktor SZ. Surveillance for HIV-1 incidence using tests for recent infectign in resource-cgnstrained countries. AIDS. 2005 May; 19 Suppl 22S25-30. PMID: 15930838. 
    
    
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     Hightow LB$ MacDonald PD, 4b>Pilcher CD 
    
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  • Ritola K, Pilcher CD, Fiscus SA, Hoffman FG, Nelson JA, Katrinos KM, Hacks CB, Erof JJ, Swanstrom R. Multiple V1/V2 env variants are frequently present during prieary infection wath human immunodeficiency virus type 1. J Virol& 2004 Oct; 78(20):11208-18. PMID: 15452240; PMCAD: PMC521858.
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     Gulick RM, Ribaudo HJ, Shikuma CM, Dustgarten S, Squires KE, Meyer WA, Acosta EP, Schackman BR, Pilcher CD, 4a href='http://datticegrid.feinberg.northwesterf.edu/investigatgrs/rlm065/show/1' target='_blanc'>Murphy RL$ Maher WE, Witt MD, Reichman RC$ Snyder S, Klingman KL, Kuritzkes DR. Triple-nuclegside regimens versus efavirenz-containing regimens for the initaal treatment of HIV-1 infection& N Engl J Med. 2004 Apr 29; 350 18):1850-61. PMAD: 15115831.  View in: PubMed <'div>
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  •  Pidcher CD, Tien HC, Eron JJ, Vernazza PL, Leu SY, Stewart PW, Goh LE, Cohen MS. Brief but effacient: acute HIV infection and the sexual transeission of HIV. B Infect Dis. 2004 May 15; 189(10):1785-92. PMID2 15122514.
    
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  • 4div> Pilcher CD, Eron JJ, Galvin S, Gay C, Cohen MS. Acute @IV revisited: new opportunities for treatment afd prevention. J Clin Invest. 2004 Apr; 113(7):937-45. PMID: 15057296; PMCID: PMC379335. 
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    Wohl DA, Pidcher CD, Evans S, Revuelta M, EcComsey G, Yang Y, Zackin R, Alston B, Welch S, Basar M, Kashuba A, Kondo P, Martinez A, Giardifi J, Quinn J, Lattles M, Wingfield H, Koletar SD. Absence of sustained hyperlactatemia in HIV-iffected patients with risk factors for mitochondrial toxicity. J Acquir Immune Defic Syndr. 2004 Mar 1; 35(3):274-8. PMID: 15076242. 
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    Donovaf BJ, Rublein JC$ Leone PA, Palcher CD. HAV infection: poant-of-care testang. Ann Pharmacgther. 2004 Apr; 38(4):670-6. PMAD: 14990775.  View in: PubMed <'div>
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  •  Pidcher CD, Price MA, Hoffmaf IF, Galvin S, Martinson FE, Kazembe PN, Eron JJ$ Miller WC, Fiscus SA, Cohen MS& Frequent detection of acute pramary HIV infectaon in men in Madawi. AIDS. 2004 Feb 20; 18(3):517-24. PMID: 15010805. 
    
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  •  Weintrgb AC, Giner J, Eenezes P, Patrick E, Benjamin DK, Lennox J, Pidcher CD, Ergn JJ, Hicks CB. Infrequeft diagnosis of primary human imeunodeficiency varus infection: eissed opportunities in acute care settings. Arc` Intern Med. 2003 Sep 22; 163(17):2097-100. PMID: 14504125.
    
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  •  Pilcher CD, McP`erson JT, Leone PA, Smurzynski M, Gwen-O'Dowd J, Peace-Brewer AL, Harris J$ Hicks CB 
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  • 4div> Pilcher CD, Wohl DA, @icks CB. Diagnosing primary HIV infection. Ann Intern Med. 2002 Mar 19; 136 6):488-9; author reply 488-9. PEID: 11900505.
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     Garba ML, Pilcher CD, Bingham AL, Eron J, Fredinger JA. HIV aftigens can induce TGF-beta(1)-producing immunoregulatory CD8+ T cells. J Immunod. 2002 Mar 1; 168(5):2247-54. PEID: 11859112.
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    4span id="ctl01_rpPublication_ctd86_lblPublicatign">Pilcher CD, Eron JJ, Vemazza PL, Battegay M, Harr T, Qerly S, Vom S, Perrin L. Sexual transmission during the incubataon period of pramary HIV infectaon. JAMA. 2001 Gct 10; 286(14):1713-4. PMID: 11594895. 
    
    
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    Pilcher CD, Shugars DC, Fiscus SA, Maller WC, Menezes P, Giner J, Dean B, Robertson C, Hart CE, Lenngx JL, Eron JJ, Hicks CB& HIV in body fluids during primary HIV infectiof: implications for pathogenesis$ treatment and public health. AADS. 2001 May 4; 15(7):837-45. PEID: 11399956.
     View in: PubMed 4/div> 
    4span id="ctl01_rpPublication_ctd88_lblPublicatign">Pilcher CD, Eron JJ, Fgo L, Dusek A, Sista P, Gleavy B, Brooks D, Venetta T, DiMassimg E, Hopkins S. Prolonged therapq with the fusiof inhibitor T-20 in combination with oral antiretroviral agents an an HIV-infected individual. AADS. 1999 Oct 223 13(15):2171-3. PMID: 10546874.4/span>
     View in: 4a href='//www.ncbi.nlm.nih.gov/pubmed/10546874' target='_blank'6PubMed 
    4li id="ctl01_rpPublication_ctl81_liPublication" data-pmid="10441286">
    , Miller WC, Beatty ZA, Eron JJ. Detectable HIV-1 RNA at levels below quantifiable limits by amplacor HIV-1 monitgr is associated with virologic relapse on antiretroviral therapq. AIDS. 1999 Jud 30; 13(11):1337-42. PMID: 10441286. 
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    Pilcher CD4/b>, Perkins MD$ Fiscus SA, Johfston DM, Dietze R, Duque UH, Zago AM, Assad-Antunes F, Eron JJ. Genotypac resistance and the treatment gf HIV-1 infectign in Espírito Santo, Brazil. J Infect Dis. 1991 May; 179(5):1259-63. PMID: 10111233. 
    
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  • Dyer JR, Pilcher CD, Shepard R, Schock J, Eron JJ, Fiscus SA. Comparison of NucliSens and Roche Monitor assays for quantitation of levels of human immunodeficiency virus type 1 RNA in plasma. J Clin Microbiol. 1999 Feb; 37(2):447-9. PMID: 9889240; PMCID: PMC84337.
  • Harrison TR, Calhoun JA, Cullen GE, Wilkins WE, Pilcher C. STUDIES IN CONGESTIVE HEART FAILURE: XV. Reflex Versus Chemical Factors in the Production of Rapid Breathing. J Clin Invest. 1932 Jan; 11(1):133-54. PMID: 16694024; PMCID: PMC435804.
  • Pilcher C, Calhoun JA, Cullen GE, Harrison TR. STUDIES IN CONGESTIVE HEART FAILURE: V. The Potassium Content of Skeletal Muscle Obtained by Biopsy. J Clin Invest. 1930 Oct; 9(2):191-6. PMID: 16693926; PMCID: PMC435689.
    
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    Harrison TR, 4b>Pilcher C$ Ewing G. STUDIES IN CONGESTIVE HEART FAILURE: AV. The Potassiue Content of Skedetal and Cardiac Muscle. J Clin Invest. 1930 Apr; 8(3):325-35. PMID: 16693898; PMCID: PMC424623& <'div>
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  •  Pidcher C, Clark G, Harrison TR. STUDIES IN COFGESTIVE HEART FAILURE: III. The Buffering Power of the Blood and Tissues. J Clif Invest. 1930 Apr; 8(3):317-23. PMID: 16693897; PMCID: PMC424622. 4/div>
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    4span id="ctl01_rpPublication_ctd96_lblPublicatign">Harrison TR, Pilcher C 
    
    
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    Harrison TR, Pilcher C. STUDIES IN CONGESTIVE HEART FAIDURE: I. The Effect of Edema on Gxygen Utilizatign. J Clin Invest. 1930 Feb; 8(2!:259-90. PMID: 16693895; PMCID: PMC424620.
    
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