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Warner Greene, MD, PhD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address1650 Owens St
San Francisco CA 94107
Phone415-734-4805
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    Collapse Biography 
    Collapse Education and Training
    Stanford University, Palo Alto, CABA1971
    Washington University School of Medicine, St. Louis, MOMD, PhD1977Medical Scientist Training Program
    Massachusetts General Hospital, Boston, MA1978Internal Medicine Internship
    Massachusetts General Hospital, Boston, MA1979Internal Medicine Residency
    Collapse Awards and Honors
    American Academy of Arts & Sciences2014Elected as Member
    Association of American Physicians2013Francis Gilman Blake Award
    Association of American Physicians2012  - 2013President
    Ohio State University Center for Retrovirus Research2012Distinguished Research Career Award
    Washington University in St. Louis2012Alumni Achievement Award
    Association of American Physicians2011  - 2012President-Elect
    Global Virus Network2011  - presCenter Director
    National Academy of Medicine2005Elected as Member
    Association of American Physicians2005  - 2011Councilor
    American Association for the Advancement of Science2004Elected Fellow
    AIDS Memorial Advisory Board2003  - presHonorary Co-Chair
    Academic Alliance Foundation2003  - presBoard of Directors
    Waterford Project2000Executive Committee and Chair of Scientific Committee
    ISI Highly Cited Researchers2001Selected as Original Member
    American Society for Clinical Investigation1998  - 2001Institutional Representative
    California Academy of Medicine1993Elected
    American Society for Clinical Investigation1993  - 1994Vice President
    Mayor's AIDS Scientific Advisory Council1997  - 1998Member
    Keystone AIDS Symposium1995Co-Chair
    1st-3rd National Conferences on Human Retroviruses & Related Infections1994  - 1996Co-Chair, Scientific Committee
    Association of American Physicians1990Elected
    Institute for Scientific Information (Science Citation Index)1981  - 1988100 Most Cited Scientists
    American Federation for Clinical Research1987Recipient, Outstanding Investigator Award
    American Society for Clinical Investigation1985Elected
    American Rheumatism Association1988Recipient, Young Investigator Award
    Washington Academy of Sciences1984Recipient, Award in the Biological Sciences
    Alpha Omega Alpha1977Elected Member
    St. Louis Internists1977Prize in Medicine
    Sigma Xi1976Research Honorary
    California Heart Association1970Recipient, Research Fellowship Award
    Stanford University1970  - 1971Honors Program in Biology

    Collapse Overview 
    Collapse Overview
    Warner C. Greene, MD, PhD is Director of the Gladstone Center for HIV Cure Research, Senior Investigator, and Nick and Sue Hellmann Distinguished Professor of Translational Medicine at the Gladstone Institute of Virology and Immunology (GIVI). He is the Founding and Emeritus Director of GIVI. Dr. Greene is also Professor of Medicine, Microbiology and of Immunology at UCSF. Dr. Greene is a member of the Institute of Medicine of the National Academies and a fellow of the American Academy for the Advancement of Science. He also serves as Co-Director of the UCSF-Gladstone Center for AIDS Research, and has served as a Councilor and President of the Association of American Physicians. Dr. Greene earned a bachelor’s degree at Stanford University and an MD/PhD at Washington University School of Medicine. He took his internship and residency training in Medicine at the Massachusetts General Hospital at Harvard. After serving as a Senior Investigator at the National Cancer Institute and a Professor of Medicine and Howard Hughes Investigator at Duke University Medical Center, Dr. Greene accepted his current position as the Founding Director of the Gladstone Institute of Virology and Immunology in 1991. The ongoing research in Dr. Greene’s laboratory focuses on the molecular mechanisms underlying HIV pathogenesis, latency, and transmission. He is the author of more than 380 scientific papers and has been recognized as one of the 100 Most Cited Scientists in the world. In 2007, Dr. Greene expanded his work to include global health in sub-Saharan Africa in his service as president and executive chairman of the Accordia Global Health Foundation. Accordia established the Infectious Diseases Institute at Makerere University in Uganda, which has trained thousands of African health care workers, is caring for 30,000 HIV-infected patients, and has brought health care to nearly 500,000 people living in remote rural regions of Uganda. In 2016, Accordia merged with Africare.

    Collapse Research 
    Collapse Research Activities and Funding
    Exploring HIV-associated Neurocognitive Disorder (HAND) and HIV Latency at the Single Cell Level in Cerebral Organoids
    NIH/NIDA R01DA049525Sep 15, 2019 - Aug 31, 2024
    Role: Principal Investigator
    Exploiting the Host-HIV Interface To Identify Biomarkers Predicting Time to Viral Rebound after Treatment Interruption
    NIH/NIAID P01AI131374Aug 8, 2017 - Jul 31, 2022
    Role: Principal Investigator
    Assessing the root causes of chronic inflammation in HIV-infected individuals using drugs of abuse
    NIH/NIDA R01DA044605Jul 15, 2017 - May 31, 2022
    Role: Principal Investigator
    Durable Antibody Mediated Protection Against HIV
    NIH 1P01AI124912-01Aug 15, 2016 - Jul 31, 2020
    Role: Project Leader
    Durable Antibody Mediated Protection Against HIV
    NIH P01AI124912Aug 15, 2016 - Jul 31, 2020
    Role: Co-Investigator
    amfAR Institute for Cure Research
    amfAR, The American Foundation for AIDS Research Jan 1, 2016 - Dec 31, 2020
    Role: Project Director
    Understanding How CD4 T Cells Die During HIV Infection
    NIH/NIAID R56AI118574Jul 1, 2015 - Jun 30, 2016
    Role: Principal Investigator
    HIV without AIDS: A Radically Different Approach to Help the Developing World
    NIH/NIDA DP1DA036502Sep 15, 2013 - May 31, 2018
    Role: Principal Investigator
    Host Factors Influencing HIV Viral Load and Infectivity in Semen
    NIH/NICHD R01HD074511Jul 25, 2012 - May 31, 2017
    Role: Co-Investigator
    HIV-Induced CD4 T-Cell Depletion: An Innate Host Defense Gone Awry?
    NIH/NIAID R21AI102782Jul 1, 2012 - Jun 30, 2014
    Role: Principal Investigator
    Martin Delaney Collaboratory to Eradicate HIV-1 Infection
    NIH U19AI096113Jul 8, 2011 - Jun 30, 2016
    Role: Co-Investigator
    Exploring HIV-Host Interactions in the Female Reproductive Tract
    NIH/NIAID P01AI083050Sep 1, 2009 - Aug 31, 2014
    Role: Principal Investigator
    Exploring and Exploiting APOBEC3G Biology
    NIH/NIAID R56AI065329Sep 1, 2009 - Aug 31, 2011
    Role: Principal Investigator
    Effects of Menopause on T-cell Immunity in HIV-Infected Women
    NIH/NIAID R21AI080409Sep 25, 2008 - Aug 30, 2011
    Role: Principal Investigator
    Regulation and Action of APOBEC3G
    NIH/NIAID R01AI065329Jul 1, 2005 - Oct 31, 2009
    Role: Principal Investigator
    Molecular Mechanisms of HIV Post-Integration Latency
    NIH/NIAID P01AI058708Sep 30, 2004 - Jan 31, 2010
    Role: Co-Investigator
    UCSF-Gladstone Center for AIDS Research
    NIH/NIAID P30AI027763Jul 15, 2002 - Sep 14, 2007
    Role: Co-Investigator
    Exploring How HTLV-1 Tax Induces T Cell Leukemia
    NIH/NCI R01CA089001Jul 1, 2002 - Jun 30, 2008
    Role: Principal Investigator
    Microglia and the Neuropathogenesis of HIV Disease
    NIH/NIMH R01MH064396Apr 1, 2002 - Sep 30, 2007
    Role: Principal Investigator
    GENDER EFFECTS ON HIV BIOLOGY
    NIH/NICHD P01HD040543Apr 23, 2001 - Mar 31, 2008
    Role: Principal Investigator
    HIV FITNESS, VIRULENCE AND EVOLUTION
    NIH/NCI R01CA086814Jul 1, 2000 - Jun 30, 2004
    Role: Principal Investigator
    ANALYSIS OF THE ROLE OF VPR IN HIV PATHOGENESIS
    NIH/NIAID R01AI045324May 15, 2000 - Apr 30, 2005
    Role: Principal Investigator
    UCSF-GVI Center for AIDS Research
    NIH 4P30AI027763-25Mar 1, 1997 - Aug 31, 2017
    Role: Co-Investigator
    Role Description: Dr. Greene serves as Co-Director of the UCSF–GIVI CFAR with Dr. Paul Volberding, and is Director of the CFAR Developmental Core.
    IL2 RECEPTORS--ANALYSIS OF ASSEMBLY AND SIGNALING
    NIH/NIAID R01AI036452Sep 30, 1995 - Aug 31, 2001
    Role: Principal Investigator
    Signal Transduction by Cytokine Receptors in Vivo
    NIH/NIGMS R01GM054351Aug 1, 1995 - Mar 31, 2005
    Role: Principal Investigator
    CONFERENCE ON HIV PATHOGENESIS
    NIH/NIAID R13AI037515Jan 1, 1995 - Dec 31, 1995
    Role: Principal Investigator
    PURCHASE FACS VANTAGE FLOW CYTOMETER
    NIH/NCRR S10RR008263Jun 1, 1994 - May 31, 1995
    Role: Principal Investigator
    INHIBITION OF HIV-1 GROWTH TRANSCRIPTION
    NIH/NIAID R01AI029117Sep 30, 1989 - Jul 31, 1994
    Role: Principal Investigator
    NEF GENE OF HIV-1
    NIH/NIAID R01AI028240Apr 1, 1989 - Mar 31, 2001
    Role: Principal Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000083Oct 1, 1974 - Sep 29, 2006
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Global Health
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. SARS-CoV-2-specific T cells exhibit unique features characterized by robust helper function, lack of terminal differentiation, and high proliferative potential. bioRxiv. 2020 Jun 08. Neidleman J, Luo X, Frouard J, Xie G, Gurjot G, Stein ES, McGregor M, Ma T, George AF, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR. PMID: 32577663.
      View in: PubMed   Mentions:
    2. HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread. Elife. 2020 May 26; 9. Ma T, Luo X, George AF, Mukherjee G, Sen N, Spitzer TL, Giudice LC, Greene WC, Roan NR. PMID: 32452381.
      View in: PubMed   Mentions:    Fields:    
    3. Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection. PLoS Pathog. 2020 04; 16(4):e1008450. Hsiao F, Frouard J, Gramatica A, Xie G, Telwatte S, Lee GQ, Roychoudhury P, Schwarzer R, Luo X, Yukl SA, Lee S, Hoh R, Deeks SG, Jones RB, Cavrois M, Greene WC, Roan NR. PMID: 32353080.
      View in: PubMed   Mentions:    Fields:    
    4. Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling. Hum Reprod. 2020 Mar 27; 35(3):617-640. George AF, Jang KS, Nyegaard M, Neidleman J, Spitzer TL, Xie G, Chen JC, Herzig E, Laustsen A, Marques de Menezes EG, Houshdaran S, Pilcher CD, Norris PJ, Jakobsen MR, Greene WC, Giudice LC, Roan NR. PMID: 32219408.
      View in: PubMed   Mentions:    Fields:    
    5. Reduce and Control: A Combinatorial Strategy for Achieving Sustained HIV Remissions in the Absence of Antiretroviral Therapy. Viruses. 2020 Feb 08; 12(2). Schwarzer R, Gramatica A, Greene WC. PMID: 32046251.
      View in: PubMed   Mentions:    Fields:    
    6. HIV-2 Depletes CD4 T Cells through Pyroptosis despite Vpx-Dependent Degradation of SAMHD1. J Virol. 2019 12 15; 93(24). Luo X, Herzig E, Doitsh G, Grimmett ZW, Muñoz-Arias I, Greene WC. PMID: 31578293.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency. Retrovirology. 2019 11 11; 16(1):32. Telwatte S, Morón-López S, Aran D, Kim P, Hsieh C, Joshi S, Montano M, Greene WC, Butte AJ, Wong JK, Yukl SA. PMID: 31711503.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    8. Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform. Cell. 2019 Oct 31; 179(4):880-894.e10. Herzig E, Kim KC, Packard TA, Vardi N, Schwarzer R, Gramatica A, Deeks SG, Williams SR, Landgraf K, Killeen N, Martin DW, Weinberger LS, Greene WC. PMID: 31668804.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    9. Tissue microenvironment initiates an immune response to structural components of Staphylococcus aureus. Exp Dermatol. 2019 02; 28(2):161-168. Mainzer C, Packard T, Bordes S, Closs B, Greene WC, Elias PM, Uchida Y. PMID: 30566255.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    10. Distinct mechanisms regulate IL1B gene transcription in lymphoid CD4 T cells and monocytes. Cytokine. 2018 11; 111:373-381. Pulugulla SH, Packard TA, Galloway NLK, Grimmett ZW, Doitsh G, Adamik J, Galson DL, Greene WC, Auron PE. PMID: 30300855.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    11. Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma. Biol Reprod. 2018 08 01; 99(2):336-348. Martin JW, Chen JC, Neidleman J, Tatsumi K, Hu J, Giudice LC, Greene WC, Roan NR. PMID: 29518187.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    12. Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4+ T cells. Elife. 2018 05 01; 7. Battivelli E, Dahabieh MS, Abdel-Mohsen M, Svensson JP, Tojal Da Silva I, Cohn LB, Gramatica A, Deeks S, Greene WC, Pillai SK, Verdin E. PMID: 29714165.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    13. Mass Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells. Cell Rep. 2017 07 25; 20(4):984-998. Cavrois M, Banerjee T, Mukherjee G, Raman N, Hussien R, Rodriguez BA, Vasquez J, Spitzer MH, Lazarus NH, Jones JJ, Ochsenbauer C, McCune JM, Butcher EC, Arvin AM, Sen N, Greene WC, Roan NR. PMID: 28746881.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    14. Semen amyloids participate in spermatozoa selection and clearance. Elife. 2017 06 27; 6. Roan NR, Sandi-Monroy N, Kohgadai N, Usmani SM, Hamil KG, Neidleman J, Montano M, Ständker L, Röcker A, Cavrois M, Rosen J, Marson K, Smith JF, Pilcher CD, Gagsteiger F, Sakk O, O'Rand M, Lishko PV, Kirchhoff F, Münch J, Greene WC. PMID: 28653619.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    15. SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency. Cell Host Microbe. 2017 May 10; 21(5):569-579.e6. Boehm D, Jeng M, Camus G, Gramatica A, Schwarzer R, Johnson JR, Hull PA, Montano M, Sakane N, Pagans S, Godin R, Deeks SG, Krogan NJ, Greene WC, Ott M. PMID: 28494238.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    16. Corrigendum: Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection. Nature. 2017 04 06; 544(7648):124. Doitsh G, Galloway NL, Geng X, Yang Z, Monroe KM, Zepeda O, Hunt PW, Hatano H, Sowinski S, Muñoz-Arias I, Greene WC. PMID: 28329768.
      View in: PubMed   Mentions: 1     Fields:    
    17. Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells. PLoS Pathog. 2017 02; 13(2):e1006163. Neidleman JA, Chen JC, Kohgadai N, Müller JA, Laustsen A, Thavachelvam K, Jang KS, Stürzel CM, Jones JJ, Ochsenbauer C, Chitre A, Somsouk M, Garcia MM, Smith JF, Greenblatt RM, Münch J, Jakobsen MR, Giudice LC, Greene WC, Roan NR. PMID: 28207890.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    18. The mTOR Complex Controls HIV Latency. Cell Host Microbe. 2016 Dec 14; 20(6):785-797. Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, Krogan NJ, Siliciano RF, Weissman JS, Verdin E. PMID: 27978436.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    19. Stimulating the RIG-I pathway to kill cells in the latent HIV reservoir following viral reactivation. Nat Med. 2016 07; 22(7):807-11. Li P, Kaiser P, Lampiris HW, Kim P, Yukl SA, Havlir DV, Greene WC, Wong JK. PMID: 27294875.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    20. Gallic Acid Is an Antagonist of Semen Amyloid Fibrils That Enhance HIV-1 Infection. J Biol Chem. 2016 Jul 01; 291(27):14045-55. LoRicco JG, Xu CS, Neidleman J, Bergkvist M, Greene WC, Roan NR, Makhatadze GI. PMID: 27226574.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    21. Dissecting How CD4 T Cells Are Lost During HIV Infection. Cell Host Microbe. 2016 Mar 09; 19(3):280-91. Doitsh G, Greene WC. PMID: 26962940.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    22. Blood-Derived CD4 T Cells Naturally Resist Pyroptosis during Abortive HIV-1 Infection. Cell Host Microbe. 2015 Oct 14; 18(4):463-70. Muñoz-Arias I, Doitsh G, Yang Z, Sowinski S, Ruelas D, Greene WC. PMID: 26468749.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    23. Cell-to-Cell Transmission of HIV-1 Is Required to Trigger Pyroptotic Death of Lymphoid-Tissue-Derived CD4 T Cells. Cell Rep. 2015 Sep 08; 12(10):1555-1563. Galloway NL, Doitsh G, Monroe KM, Yang Z, Muñoz-Arias I, Levy DN, Greene WC. PMID: 26321639.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    24. MicroRNA-155 Reinforces HIV Latency. J Biol Chem. 2015 May 29; 290(22):13736-48. Ruelas DS, Chan JK, Oh E, Heidersbach AJ, Hebbeler AM, Chavez L, Verdin E, Rape M, Greene WC. PMID: 25873391.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    25. Semen enhances HIV infectivity and impairs the antiviral efficacy of microbicides. Sci Transl Med. 2014 Nov 12; 6(262):262ra157. Zirafi O, Kim KA, Roan NR, Kluge SF, Müller JA, Jiang S, Mayer B, Greene WC, Kirchhoff F, Münch J. PMID: 25391483.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    26. HIV-1 Fusion Assay. Bio Protoc. 2014 Aug 20; 4(16). Cavrois M, Neidleman J, Greene WC. PMID: 27525294.
      View in: PubMed   Mentions:
    27. A new activity for SAMHD1 in HIV restriction. Nat Med. 2014 Aug; 20(8):808-9. Yang Z, Greene WC. PMID: 25100520.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    28. Liquefaction of semen generates and later degrades a conserved semenogelin peptide that enhances HIV infection. J Virol. 2014 Jul; 88(13):7221-34. Roan NR, Liu H, Usmani SM, Neidleman J, Müller JA, Avila-Herrera A, Gawanbacht A, Zirafi O, Chu S, Dong M, Kumar ST, Smith JF, Pollard KS, Fändrich M, Kirchhoff F, Münch J, Witkowska HE, Greene WC. PMID: 24741080.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    29. Interaction of fibronectin with semen amyloids synergistically enhances HIV infection. J Infect Dis. 2014 Oct 01; 210(7):1062-6. Roan NR, Chu S, Liu H, Neidleman J, Witkowska HE, Greene WC. PMID: 24719472.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    30. Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen. Nat Commun. 2014 Apr 01; 5:3508. Usmani SM, Zirafi O, Müller JA, Sandi-Monroy NL, Yadav JK, Meier C, Weil T, Roan NR, Greene WC, Walther P, Nilsson KP, Hammarström P, Wetzel R, Pilcher CD, Gagsteiger F, Fändrich M, Kirchhoff F, Münch J. PMID: 24691351.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    31. Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts. Hum Reprod. 2014 Jun; 29(6):1255-70. Chen JC, Johnson BA, Erikson DW, Piltonen TT, Barragan F, Chu S, Kohgadai N, Irwin JC, Greene WC, Giudice LC, Roan NR. PMID: 24626806.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    32. Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection. Nature. 2014 Jan 23; 505(7484):509-14. Doitsh G, Galloway NL, Geng X, Yang Z, Monroe KM, Zepeda O, Hunt PW, Hatano H, Sowinski S, Muñoz-Arias I, Greene WC. PMID: 24356306.
      View in: PubMed   Mentions: 298     Fields:    Translation:HumansCells
    33. An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients. PLoS Pathog. 2013; 9(12):e1003834. Spina CA, Anderson J, Archin NM, Bosque A, Chan J, Famiglietti M, Greene WC, Kashuba A, Lewin SR, Margolis DM, Mau M, Ruelas D, Saleh S, Shirakawa K, Siliciano RF, Singhania A, Soto PC, Terry VH, Verdin E, Woelk C, Wooden S, Xing S, Planelles V. PMID: 24385908.
      View in: PubMed   Mentions: 166     Fields:    Translation:HumansCells
    34. IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV. Science. 2014 Jan 24; 343(6169):428-32. Monroe KM, Yang Z, Johnson JR, Geng X, Doitsh G, Krogan NJ, Greene WC. PMID: 24356113.
      View in: PubMed   Mentions: 165     Fields:    Translation:HumansCells
    35. Enhanced fusion and virion incorporation for HIV-1 subtype C envelope glycoproteins with compact V1/V2 domains. J Virol. 2014 Feb; 88(4):2083-94. Cavrois M, Neidleman J, Santiago ML, Derdeyn CA, Hunter E, Greene WC. PMID: 24335304.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    36. Solutions to global health challenges: no more Band-Aids. J Clin Invest. 2013 Nov; 123(11):4967-70. Greene WC. PMID: 24177468.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    37. Calcium/calcineurin synergizes with prostratin to promote NF-?B dependent activation of latent HIV. PLoS One. 2013; 8(10):e77749. Chan JK, Bhattacharyya D, Lassen KG, Ruelas D, Greene WC. PMID: 24204950.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    38. An integrated overview of HIV-1 latency. Cell. 2013 Oct 24; 155(3):519-29. Ruelas DS, Greene WC. PMID: 24243012.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansCells
    39. Evasion of superinfection exclusion and elimination of primary viral RNA by an adapted strain of hepatitis C virus. J Virol. 2013 Dec; 87(24):13354-69. Webster B, Ott M, Greene WC. PMID: 24089557.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    40. Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein. PLoS Pathog. 2013; 9(4):e1003302. Vogt DA, Camus G, Herker E, Webster BR, Tsou CL, Greene WC, Yen TS, Ott M. PMID: 23593007.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    41. Rapid intracellular competition between hepatitis C viral genomes as a result of mitosis. J Virol. 2013 Jan; 87(1):581-96. Webster B, Wissing S, Herker E, Ott M, Greene WC. PMID: 23097449.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    42. [Role of semen-derived amyloid fibrils as facilitators of HIV infection]. Med Sci (Paris). 2012 Apr; 28(4):358-60. Roan NR, Cavrois M, Greene WC. PMID: 22549858.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    43. Dynamic roles for NF-?B in HTLV-I and HIV-1 retroviral pathogenesis. Immunol Rev. 2012 Mar; 246(1):286-310. Chan JK, Greene WC. PMID: 22435562.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    44. Role of retroviral restriction factors in the interferon-a-mediated suppression of HIV-1 in vivo. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):3035-40. Pillai SK, Abdel-Mohsen M, Guatelli J, Skasko M, Monto A, Fujimoto K, Yukl S, Greene WC, Kovari H, Rauch A, Fellay J, Battegay M, Hirschel B, Witteck A, Bernasconi E, Ledergerber B, Günthard HF, Wong JK. PMID: 22315404.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    45. A flexible model of HIV-1 latency permitting evaluation of many primary CD4 T-cell reservoirs. PLoS One. 2012; 7(1):e30176. Lassen KG, Hebbeler AM, Bhattacharyya D, Lobritz MA, Greene WC. PMID: 22291913.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    46. Differential transmission of HIV traversing fetal oral/intestinal epithelia and adult oral epithelia. J Virol. 2012 Mar; 86(5):2556-70. Tugizov SM, Herrera R, Veluppillai P, Greenspan D, Soros V, Greene WC, Levy JA, Palefsky JM. PMID: 22205732.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    47. Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection. Cell Host Microbe. 2011 Dec 15; 10(6):541-50. Roan NR, Müller JA, Liu H, Chu S, Arnold F, Stürzel CM, Walther P, Dong M, Witkowska HE, Kirchhoff F, Münch J, Greene WC. PMID: 22177559.
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    86. A plea for justice for jailed medical workers. Science. 2006 Nov 10; 314(5801):924-5. Ahuja SK, Aiuti F, Berkhout B, Biberfeld P, Burton DR, Colizzi V, Deeks SG, Desrosiers RC, Dierich MP, Doms RW, Emerman M, Gallo RC, Girard M, Greene WC, Hoxie JA, Hunter E, Klein G, Korber B, Kuritzkes DR, Lederman MM, Malim MH, Marx PA, McCune JM, McMichael A, Miller C, Miller V, Montagnier L, Montefiori DC, Moore JP, Nixon DF, Overbaugh J, Pauza CD, Richman DD, Saag MS, Sattentau Q, Schooley RT, Shattock R, Shaw GM, Stevenson M, Trkola A, Wainberg MA, Weiss RA, Wolinsky S, Zack JA. PMID: 17062652.
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    123. A sensitive and specific enzyme-based assay detecting HIV-1 virion fusion in primary T lymphocytes. Nat Biotechnol. 2002 Nov; 20(11):1151-4. Cavrois M, De Noronha C, Greene WC. PMID: 12355096.
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    124. Insights into the biology of HIV-1 viral protein R. DNA Cell Biol. 2002 Sep; 21(9):679-88. Sherman MP, De Noronha CM, Williams SA, Greene WC. PMID: 12396611.
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    125. Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy. Nat Med. 2002 Jul; 8(7):673-80. Greene WC, Peterlin BM. PMID: 12091904.
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    126. Slipping through the door: HIV entry into the nucleus. Microbes Infect. 2002 Jan; 4(1):67-73. Sherman MP, Greene WC. PMID: 11825777.
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    127. HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells. J Exp Med. 2001 Nov 19; 194(10):1407-19. Eckstein DA, Sherman MP, Penn ML, Chin PS, De Noronha CM, Greene WC, Goldsmith MA. PMID: 11714748.
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    128. Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr. Science. 2001 Nov 02; 294(5544):1105-8. de Noronha CM, Sherman MP, Lin HW, Cavrois MV, Moir RD, Goldman RD, Greene WC. PMID: 11691994.
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    129. Duration of nuclear NF-kappaB action regulated by reversible acetylation. Science. 2001 Aug 31; 293(5535):1653-7. Fischle W, Verdin E, Greene WC. PMID: 11533489.
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    130. HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Nature. 2001 Apr 12; 410(6830):834-8. Geleziunas R, Xu W, Takeda K, Ichijo H, Greene WC. PMID: 11298454.
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    131. Human immunodeficiency virus type 1 Nef functions at the level of virus entry by enhancing cytoplasmic delivery of virions. J Virol. 2001 Mar; 75(6):2993-3000. Schaeffer E, Geleziunas R, Greene WC. PMID: 11222724.
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    132. Nucleocytoplasmic shuttling by human immunodeficiency virus type 1 Vpr. J Virol. 2001 Feb; 75(3):1522-32. Sherman MP, de Noronha CM, Heusch MI, Greene S, Greene WC. PMID: 11152524.
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    133. The NF-kappa B-inducing kinase induces PC12 cell differentiation and prevents apoptosis. J Biol Chem. 2000 Nov 03; 275(44):34021-4. Foehr ED, Bohuslav J, Chen LF, DeNoronha C, Geleziunas R, Lin X, O'Mahony A, Greene WC. PMID: 10980190.
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    134. NF-kappa B signaling promotes both cell survival and neurite process formation in nerve growth factor-stimulated PC12 cells. J Neurosci. 2000 Oct 15; 20(20):7556-63. Foehr ED, Lin X, O'Mahony A, Geleziunas R, Bradshaw RA, Greene WC. PMID: 11027214.
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    135. Functional and structural characterization of synthetic HIV-1 Vpr that transduces cells, localizes to the nucleus, and induces G2 cell cycle arrest. J Biol Chem. 2000 Oct 13; 275(41):32016-26. Henklein P, Bruns K, Sherman MP, Tessmer U, Licha K, Kopp J, de Noronha CM, Greene WC, Wray V, Schubert U. PMID: 10903315.
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    136. Human immunodeficiency virus type 1 Vpr contains two leucine-rich helices that mediate glucocorticoid receptor coactivation independently of its effects on G(2) cell cycle arrest. J Virol. 2000 Sep; 74(17):8159-65. Sherman MP, de Noronha CM, Pearce D, Greene WC. PMID: 10933727.
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    137. Cotranslational dimerization of the Rel homology domain of NF-kappaB1 generates p50-p105 heterodimers and is required for effective p50 production. EMBO J. 2000 Sep 01; 19(17):4712-22. Lin L, DeMartino GN, Greene WC. PMID: 10970863.
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    138. Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta. Mol Cell Biol. 2000 Apr; 20(8):2933-40. Lin X, O'Mahony A, Mu Y, Geleziunas R, Greene WC. PMID: 10733597.
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    139. Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions. Mol Cell Biol. 2000 Feb; 20(4):1170-8. O'Mahony A, Lin X, Geleziunas R, Greene WC. PMID: 10648602.
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    140. The generation of nfkb2 p52: mechanism and efficiency. Oncogene. 1999 Nov 04; 18(46):6201-8. Heusch M, Lin L, Geleziunas R, Greene WC. PMID: 10597218.
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    141. Cutting edge: SIV Nef protein utilizes both leucine- and tyrosine-based protein sorting pathways for down-regulation of CD4. J Immunol. 1999 Sep 15; 163(6):2977-81. Bresnahan PA, Yonemoto W, Greene WC. PMID: 10477559.
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    142. The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kappaB acting through the NF-kappaB-inducing kinase and IkappaB kinases. Immunity. 1999 Feb; 10(2):271-80. Lin X, Cunningham ET, Mu Y, Geleziunas R, Greene WC. PMID: 10072079.
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    143. Characterization of HIV-1 vpr nuclear import: analysis of signals and pathways. J Cell Biol. 1998 Nov 16; 143(4):875-85. Jenkins Y, McEntee M, Weis K, Greene WC. PMID: 9817747.
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    144. A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor. Curr Biol. 1998 Nov 05; 8(22):1235-8. Bresnahan PA, Yonemoto W, Ferrell S, Williams-Herman D, Geleziunas R, Greene WC. PMID: 9811606.
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    145. Molecular determinants of NF-kappaB-inducing kinase action. Mol Cell Biol. 1998 Oct; 18(10):5899-907. Lin X, Mu Y, Cunningham ET, Marcu KB, Geleziunas R, Greene WC. PMID: 9742107.
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    146. Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases. Mol Cell Biol. 1998 Sep; 18(9):5157-65. Geleziunas R, Ferrell S, Lin X, Mu Y, Cunningham ET, Grant M, Connelly MA, Hambor JE, Marcu KB, Greene WC. PMID: 9710600.
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    147. Diminished spontaneous apoptosis in lymphocytes from human immunodeficiency virus-infected long-term nonprogressors. J Infect Dis. 1998 Sep; 178(3):669-79. Liegler TJ, Yonemoto W, Elbeik T, Vittinghoff E, Buchbinder SP, Greene WC. PMID: 9728534.
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    148. Cotranslational biogenesis of NF-kappaB p50 by the 26S proteasome. Cell. 1998 Mar 20; 92(6):819-28. Lin L, DeMartino GN, Greene WC. PMID: 9529257.
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    149. Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation. Curr Biol. 1997 Nov 01; 7(11):817-26. Liu KD, Gaffen SL, Goldsmith MA, Greene WC. PMID: 9382798.
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    150. The 90-kDa ribosomal S6 kinase (pp90rsk) phosphorylates the N-terminal regulatory domain of IkappaBalpha and stimulates its degradation in vitro. J Biol Chem. 1997 Aug 22; 272(34):21281-8. Ghoda L, Lin X, Greene WC. PMID: 9261139.
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    151. Intravirion generation of the C-terminal core domain of HIV-1 Nef by the HIV-1 protease is insufficient to enhance viral infectivity. Virology. 1997 Aug 04; 234(2):215-25. Miller MD, Warmerdam MT, Ferrell SS, Benitez R, Greene WC. PMID: 9268152.
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    152. HIV Rev-dependent binding of SF2/ASF to the Rev response element: possible role in Rev-mediated inhibition of HIV RNA splicing. Proc Natl Acad Sci U S A. 1997 Feb 04; 94(3):973-8. Powell DM, Amaral MC, Wu JY, Maniatis T, Greene WC. PMID: 9023367.
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    153. Interaction of the human T-lymphotropic virus type 1 Tax dimer with CREB and the viral 21-base-pair repeat. J Virol. 1996 Dec; 70(12):8368-74. Tie F, Adya N, Greene WC, Giam CZ. PMID: 8970957.
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    154. Unraveling the function of HIV type 1 Nef. AIDS Res Hum Retroviruses. 1996 Nov 20; 12(17):1579-82. Geleziunas R, Miller MD, Greene WC. PMID: 8947291.
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    155. c-rel regulation of IL-2 gene expression may be mediated through activation of AP-1. J Exp Med. 1996 Nov 01; 184(5):1663-9. Shapiro VS, Mollenauer MN, Greene WC, Weiss A. PMID: 8920856.
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    156. Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity. J Biol Chem. 1996 Aug 30; 271(35):21381-90. Gaffen SL, Lai SY, Ha M, Liu X, Hennighausen L, Greene WC, Goldsmith MA. PMID: 8702919.
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    157. Inhibition of HIV replication by sense and antisense rev response elements in HIV-based retroviral vectors. J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 01; 12(4):343-51. Kim JH, McLinden RJ, Mosca JD, Vahey MT, Greene WC, Redfield RR. PMID: 8673542.
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    158. The alpha chain of the IL-2 receptor determines the species specificity of high-affinity IL-2 binding. Cytokine. 1996 Aug; 8(8):613-21. Liu KD, Greene WC, Goldsmith MA. PMID: 8894436.
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    159. Denying HIV safe haven. N Engl J Med. 1996 May 09; 334(19):1264-5. Greene WC. PMID: 8606724.
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    160. Is the Nef protein of HIV-1 required for pathogenesis? Trends Microbiol. 1996 May; 4(5):171-2; discussion 173. Miller MD, Greene WC. PMID: 8727595.
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    161. Human T lymphotropic virus-I infection of human T lymphocytes induces expression of the beta-galactoside-binding lectin, galectin-3. Am J Pathol. 1996 May; 148(5):1661-70. Hsu DK, Hammes SR, Kuwabara I, Greene WC, Liu FT. PMID: 8623933.
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    162. Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation. Mol Cell Biol. 1996 Mar; 16(3):1058-65. Sun S, Elwood J, Greene WC. PMID: 8622650.
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    163. The molecular role of the common gamma c subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexes. Proc Natl Acad Sci U S A. 1996 Jan 09; 93(1):231-5. Lai SY, Xu W, Gaffen SL, Liu KD, Longmore GD, Greene WC, Goldsmith MA. PMID: 8552611.
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    164. Interaction of HTLV-I Tax with the human proteasome: implications for NF-kappa B induction. J Acquir Immune Defic Syndr Hum Retrovirol. 1996; 13 Suppl 1:S76-84. Béraud C, Greene WC. PMID: 8797708.
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    165. Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require Shc phosphorylation or receptor association. J Biol Chem. 1995 Dec 01; 270(48):28858-63. Evans GA, Goldsmith MA, Johnston JA, Xu W, Weiler SR, Erwin R, Howard OM, Abraham RT, O'Shea JJ, Greene WC. PMID: 7499411.
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    166. Predicting progression to AIDS. Ann Intern Med. 1995 Nov 01; 123(9):726-7. Greene WC. PMID: 7574230.
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    167. Identification of a variable region within the cytoplasmic tail of the IL-2 receptor beta chain that is required for growth signal transduction. J Biol Chem. 1995 Sep 22; 270(38):22176-81. Liu KD, Lai SY, Goldsmith MA, Greene WC. PMID: 7545674.
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    168. Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain. J Biol Chem. 1995 Sep 15; 270(37):21729-37. Goldsmith MA, Lai SY, Xu W, Amaral MC, Kuczek ES, Parent LJ, Mills GB, Tarr KL, Longmore GD, Greene WC. PMID: 7665592.
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    169. Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity. Proc Natl Acad Sci U S A. 1995 Aug 01; 92(16):7192-6. Gaffen SL, Lai SY, Xu W, Gouilleux F, Groner B, Goldsmith MA, Greene WC. PMID: 7543676.
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    170. Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef. J Virol. 1995 Jul; 69(7):4112-21. Goldsmith MA, Warmerdam MT, Atchison RE, Miller MD, Greene WC. PMID: 7769669.
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    171. Ligand binding by the IL-2 receptor is modulated by intracellular determinants of the IL-2 receptor beta-chain. J Immunol. 1995 Mar 01; 154(5):2033-40. Goldsmith MA, Amaral MC, Greene WC. PMID: 7868880.
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    172. Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry. J Virol. 1995 Jan; 69(1):579-84. Miller MD, Warmerdam MT, Page KA, Feinberg MB, Greene WC. PMID: 7983759.
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    173. Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene. Mol Cell Biol. 1994 Nov; 14(11):7377-84. Sun SC, Elwood J, Béraud C, Greene WC. PMID: 7935451.
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    174. The HIV-1 nef gene acts as a positive viral infectivity factor. Trends Microbiol. 1994 Aug; 2(8):294-8. Miller MD, Feinberg MB, Greene WC. PMID: 7981973.
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    175. The cytoplasmic domain of the interleukin-2 receptor beta chain contains both unique and functionally redundant signal transduction elements. J Biol Chem. 1994 May 20; 269(20):14698-704. Goldsmith MA, Xu W, Amaral MC, Kuczek ES, Greene WC. PMID: 8182077.
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    176. The membrane proximal segment of the IL-2 receptor beta-chain acidic region is essential for IL2-dependent protein tyrosine kinase activation. Leukemia. 1994 Apr; 8 Suppl 1:S186-9. Williamson P, Merida I, Greene WC, Gaulton G. PMID: 8152289.
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    177. Autoregulation of the NF-kappa B transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs. Proc Natl Acad Sci U S A. 1994 Feb 15; 91(4):1346-50. Sun SC, Ganchi PA, Béraud C, Ballard DW, Greene WC. PMID: 8108414.
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    178. Human T-cell leukemia virus type I Tax associates with and is negatively regulated by the NF-kappa B2 p100 gene product: implications for viral latency. Mol Cell Biol. 1994 Feb; 14(2):1374-82. Béraud C, Sun SC, Ganchi P, Ballard DW, Greene WC. PMID: 8289813.
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    179. The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages. J Exp Med. 1994 Jan 01; 179(1):101-13. Miller MD, Warmerdam MT, Gaston I, Greene WC, Feinberg MB. PMID: 8270859.
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    180. A novel NF-kappa B complex containing p65 homodimers: implications for transcriptional control at the level of subunit dimerization. Mol Cell Biol. 1993 Dec; 13(12):7826-35. Ganchi PA, Sun SC, Greene WC, Ballard DW. PMID: 8246997.
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    181. Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function. EMBO J. 1993 Oct; 12(10):3879-91. Stein B, Baldwin AS, Ballard DW, Greene WC, Angel P, Herrlich P. PMID: 8404856.
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    182. AIDS and the immune system. Sci Am. 1993 Sep; 269(3):98-105. Greene WC. PMID: 8211096.
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    183. Dominant negative mutants of human T-cell leukemia virus type I Rex and human immunodeficiency virus type 1 Rev fail to multimerize in vivo. J Virol. 1993 May; 67(5):2496-502. Bogerd H, Greene WC. PMID: 8474155.
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    184. Unexpected effects of the IL-2 receptor alpha subunit on high affinity IL-2 receptor assembly and function detected with a mutant IL-2 analog. J Immunol. 1993 Apr 15; 150(8 Pt 1):3357-65. Kuziel WA, Ju G, Grdina TA, Greene WC. PMID: 8468475.
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    185. NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway. Science. 1993 Mar 26; 259(5103):1912-5. Sun SC, Ganchi PA, Ballard DW, Greene WC. PMID: 8096091.
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    186. The serine-rich cytoplasmic domain of the interleukin-2 receptor beta chain is essential for interleukin-2-dependent tyrosine protein kinase and phosphatidylinositol-3-kinase activation. J Biol Chem. 1993 Mar 25; 268(9):6765-70. Merida I, Williamson P, Kuziel WA, Greene WC, Gaulton GN. PMID: 8384218.
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    187. Multiple arginine residues within the basic domain of HTLV-I Rex are required for specific RNA binding and function. Virology. 1993 Mar; 193(1):41-9. Hammes SR, Greene WC. PMID: 8438577.
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    188. The c-rel protooncogene product represses NF-kappa B p65-mediated transcriptional activation of the long terminal repeat of type 1 human immunodeficiency virus. Proc Natl Acad Sci U S A. 1993 Feb 01; 90(3):1023-7. Doerre S, Sista P, Sun SC, Ballard DW, Greene WC. PMID: 8430069.
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    189. I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding. Mol Biol Cell. 1992 Dec; 3(12):1339-52. Ganchi PA, Sun SC, Greene WC, Ballard DW. PMID: 1493333.
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    190. Neither the LCK nor the FYN kinases are obligatory for IL-2-mediated signal transduction in HTLV-I-infected human T cells. Int Immunol. 1992 Nov; 4(11):1233-43. Mills GB, Arima N, May C, Hill M, Schmandt R, Li J, Miyamoto NG, Greene WC. PMID: 1472476.
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    191. Molecular insights into human immunodeficiency virus type 1 pathogenesis. Curr Opin Immunol. 1992 Aug; 4(4):466-74. Feinberg MB, Greene WC. PMID: 1356348.
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    192. The v-rel oncogene: insights into the mechanism of transcriptional activation, repression, and transformation. J Virol. 1992 Aug; 66(8):5018-29. Walker WH, Stein B, Ganchi PA, Hoffman JA, Kaufman PA, Ballard DW, Hannink M, Greene WC. PMID: 1321284.
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    193. IL-2-induced signal transduction involves the activation of nuclear NF-kappa B expression. J Immunol. 1992 Jul 01; 149(1):83-91. Arima N, Kuziel WA, Grdina TA, Greene WC. PMID: 1607664.
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    194. Nuclear expression of the 50- and 65-kD Rel-related subunits of nuclear factor-kappa B is differentially regulated in human monocytic cells. J Clin Invest. 1992 Jul; 90(1):121-9. Kaufman PA, Weinberg JB, Greene WC. PMID: 1634604.
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    195. Dominant-negative mutants are clustered in a domain of the human T-cell leukemia virus type I Rex protein: implications for trans dominance. J Virol. 1992 Jul; 66(7):4540-5. Weichselbraun I, Berger J, Dobrovnik M, Bogerd H, Grassmann R, Greene WC, Hauber J, Böhnlein E. PMID: 1602559.
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    196. Characterization of a novel nuclear localization signal in the HTLV-I tax transactivator protein. Virology. 1992 Mar; 187(1):316-20. Smith MR, Greene WC. PMID: 1736534.
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    197. The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression. Proc Natl Acad Sci U S A. 1992 Mar 01; 89(5):1875-9. Ballard DW, Dixon EP, Peffer NJ, Bogerd H, Doerre S, Stein B, Greene WC. PMID: 1542686.
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    198. Human T-cell leukemia virus type I Tax induces expression of the Rel-related family of kappa B enhancer-binding proteins: evidence for a pretranslational component of regulation. J Virol. 1991 Dec; 65(12):6892-9. Arima N, Molitor JA, Smith MR, Kim JH, Daitoku Y, Greene WC. PMID: 1719236.
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    199. Kappa B-specific DNA binding proteins are differentially inhibited by enhancer mutations and biological oxidation. New Biol. 1991 Oct; 3(10):987-96. Molitor JA, Ballard DW, Greene WC. PMID: 1768652.
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    200. Type I human T cell leukemia virus tax protein transforms rat fibroblasts through the cyclic adenosine monophosphate response element binding protein/activating transcription factor pathway. J Clin Invest. 1991 Sep; 88(3):1038-42. Smith MR, Greene WC. PMID: 1832173.
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    201. The type I human T-cell leukemia virus (HTLV-I) Rex trans-activator binds directly to the HTLV-I Rex and the type 1 human immunodeficiency virus Rev RNA response elements. Proc Natl Acad Sci U S A. 1991 Jul 01; 88(13):5704-8. Bogerd HP, Huckaby GL, Ahmed YF, Hanly SM, Greene WC. PMID: 1905815.
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    202. A member of the set of kappa B binding proteins, HIVEN86A, is a product of the human c-rel proto-oncogene. Oncogene. 1991 Apr; 6(4):665-7. Lee JH, Li YC, Doerre S, Sista P, Ballard DW, Greene WC, Franza BR. PMID: 2030915.
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    203. Kappa B binding proteins are constitutively expressed in an IL-2 autocrine human T cell line. J Immunol. 1991 Apr 01; 146(7):2409-16. Hémar A, Cereghini S, Cornet V, Blank V, Israël A, Greene WC, Dautry-Varsat A. PMID: 2005404.
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    204. Molecular biology of the type I human T-cell leukemia virus (HTLV-I) and adult T-cell leukemia. J Clin Invest. 1991 Mar; 87(3):761-6. Smith MR, Greene WC. PMID: 1999493.
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    205. The HTLV-I Rex response element mediates a novel form of mRNA polyadenylation. Cell. 1991 Feb 22; 64(4):727-37. Ahmed YF, Gilmartin GM, Hanly SM, Nevins JR, Greene WC. PMID: 1671761.
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    207. Rex transregulation of human T-cell leukemia virus type II gene expression. J Virol. 1991 Jan; 65(1):405-14. Kim JH, Kaufman PA, Hanly SM, Rimsky LT, Greene WC. PMID: 1985205.
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    208. Functional analyses of the type I human T-cell leukemia virus tax gene product. Trans Assoc Am Physicians. 1991; 104:78-91. Smith MR, Greene WC. PMID: 1845158.
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    209. NF-kappa B: a family of inducible and differentially expressed enhancer-binding proteins in human T cells. Proc Natl Acad Sci U S A. 1990 Dec; 87(24):10028-32. Molitor JA, Walker WH, Doerre S, Ballard DW, Greene WC. PMID: 2263603.
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    210. The v-rel oncogene encodes a kappa B enhancer binding protein that inhibits NF-kappa B function. Cell. 1990 Nov 16; 63(4):803-14. Ballard DW, Walker WH, Doerre S, Sista P, Molitor JA, Dixon EP, Peffer NJ, Hannink M, Greene WC. PMID: 2225078.
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    211. Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes. Genes Dev. 1990 Nov; 4(11):1875-85. Smith MR, Greene WC. PMID: 2276622.
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    212. Functions of the auxiliary gene products of the human immunodeficiency virus type 1. Virology. 1990 Sep; 178(1):1-5. Cullen BR, Greene WC. PMID: 2202146.
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    213. The molecular basis for the generation of the human soluble interleukin 2 receptor. Cytokine. 1990 Sep; 2(5):330-6. Rubin LA, Galli F, Greene WC, Nelson DL, Jay G. PMID: 2103332.
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    214. Structure-function analyses of the HTLV-I Rex and HIV-1 Rev RNA response elements: insights into the mechanism of Rex and Rev action. Genes Dev. 1990 Jun; 4(6):1014-22. Ahmed YF, Hanly SM, Malim MH, Cullen BR, Greene WC. PMID: 2116986.
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    215. Interleukin-2 and the IL-2 receptor: new insights into structure and function. J Invest Dermatol. 1990 Jun; 94(6 Suppl):27S-32S. Kuziel WA, Greene WC. PMID: 1693645.
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    216. The human interleukin-2 receptor: insights into subunit structure and growth signal transduction. Semin Immunol. 1990 Mar; 2(2):119-28. Fung MR, Greene WC. PMID: 2129904.
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    217. Interleukin 2-induced tyrosine phosphorylation. Interleukin 2 receptor beta is tyrosine phosphorylated. J Biol Chem. 1990 Feb 25; 265(6):3561-7. Mills GB, May C, McGill M, Fung M, Baker M, Sutherland R, Greene WC. PMID: 2303462.
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    218. Regulation of HIV-1 gene expression. Annu Rev Immunol. 1990; 8:453-75. Greene WC. PMID: 2188670.
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    219. A second sequence element located 3' to the NF-kappa B-binding site regulates IL-2 receptor-alpha gene induction. J Immunol. 1989 Dec 15; 143(12):4275-81. Pomerantz JL, Mauxion F, Yoshida M, Greene WC, Sen R. PMID: 2687377.
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    220. Nef protein of human immunodeficiency virus type 1: evidence against its role as a transcriptional inhibitor. Proc Natl Acad Sci U S A. 1989 Dec; 86(23):9549-53. Hammes SR, Dixon EP, Malim MH, Cullen BR, Greene WC. PMID: 2687884.
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    221. The same 50-kDa cellular protein binds to the negative regulatory elements of the interleukin 2 receptor alpha-chain gene and the human immunodeficiency virus type 1 long terminal repeat. Proc Natl Acad Sci U S A. 1989 Nov; 86(21):8526-30. Smith MR, Greene WC. PMID: 2813410.
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    222. Trans-dominant inactivation of HTLV-I and HIV-1 gene expression by mutation of the HTLV-I Rex transactivator. Nature. 1989 Oct 05; 341(6241):453-6. Rimsky L, Dodon MD, Dixon EP, Greene WC. PMID: 2677743.
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    223. Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements. Genes Dev. 1989 Oct; 3(10):1534-44. Hanly SM, Rimsky LT, Malim MH, Kim JH, Hauber J, Duc Dodon M, Le SY, Maizel JV, Cullen BR, Greene WC. PMID: 2482226.
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    224. Activation of the interleukin-2 receptor alpha gene: regulatory role for DNA-protein interactions flanking the kappa B enhancer. New Biol. 1989 Oct; 1(1):83-92. Ballard DW, Böhnlein E, Hoffman JA, Bogerd HP, Dixon EP, Franza BR, Greene WC. PMID: 2518691.
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    225. Regulatory pathways governing HIV-1 replication. Cell. 1989 Aug 11; 58(3):423-6. Cullen BR, Greene WC. PMID: 2569361.
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    226. HIV-1, HTLV-1 and normal T-cell growth: transcriptional strategies and surprises. Immunol Today. 1989 Aug; 10(8):272-8. Greene WC, Böhnlein E, Ballard DW. PMID: 2679647.
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    227. Induction of interleukin-2 receptor-alpha gene expression is regulated by post-translational activation of kappa B specific DNA binding proteins. J Biol Chem. 1989 May 25; 264(15):8475-8. Böhnlein E, Ballard DW, Bogerd H, Peffer NJ, Lowenthal JW, Greene WC. PMID: 2785992.
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    228. Tumor necrosis factor-alpha activation of the IL-2 receptor-alpha gene involves the induction of kappa B-specific DNA binding proteins. J Immunol. 1989 May 01; 142(9):3121-8. Lowenthal JW, Ballard DW, Bogerd H, Böhnlein E, Greene WC. PMID: 2785134.
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    229. Kappa B-specific DNA binding proteins: role in the regulation of human interleukin-2 gene expression. Science. 1989 Apr 28; 244(4903):457-60. Hoyos B, Ballard DW, Böhnlein E, Siekevitz M, Greene WC. PMID: 2497518.
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    230. Stimulation of the human immunodeficiency virus type 1 enhancer by the human T-cell leukemia virus type I tax gene product involves the action of inducible cellular proteins. J Virol. 1989 Apr; 63(4):1578-86. Böhnlein E, Siekevitz M, Ballard DW, Lowenthal JW, Rimsky L, Bogérd H, Hoffman J, Wano Y, Franza BR, Greene WC. PMID: 2784507.
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    231. Tumor necrosis factor alpha induces proteins that bind specifically to kappa B-like enhancer elements and regulate interleukin 2 receptor alpha-chain gene expression in primary human T lymphocytes. Proc Natl Acad Sci U S A. 1989 Apr; 86(7):2331-5. Lowenthal JW, Ballard DW, Böhnlein E, Greene WC. PMID: 2494663.
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    232. HIV-1, HTLV-I and the interleukin-2 receptor: insights into transcriptional control. Haematol Blood Transfus. 1989; 32:393-401. Böhnlein E, Lowenthal JW, Wano Y, Franza BR, Ballard DW, Greene WC. PMID: 2625257.
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    233. Stable expression of the tax gene of type I human T-cell leukemia virus in human T cells activates specific cellular genes involved in growth. Proc Natl Acad Sci U S A. 1988 Dec; 85(24):9733-7. Wano Y, Feinberg M, Hosking JB, Bogerd H, Greene WC. PMID: 3059351.
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    234. Co-internalization of the p55 and p70 subunits of the high-affinity human interleukin 2 receptor. Evidence for a stable ternary receptor complex. J Exp Med. 1988 Nov 01; 168(5):1923-8. Fung MR, Ju G, Greene WC. PMID: 3263468.
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    235. Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein. Nature. 1988 Oct 20; 335(6192):738-40. Rimsky L, Hauber J, Dukovich M, Malim MH, Langlois A, Cullen BR, Greene WC. PMID: 3262832.
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    236. Identification of specific residues of human interleukin 2 that affect binding to the 70-kDa subunit (p70) of the interleukin 2 receptor. Proc Natl Acad Sci U S A. 1988 Oct; 85(20):7709-13. Collins L, Tsien WH, Seals C, Hakimi J, Weber D, Bailon P, Hoskings J, Greene WC, Toome V, Ju G. PMID: 3051003.
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    237. HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene. Science. 1988 Sep 23; 241(4873):1652-5. Ballard DW, Böhnlein E, Lowenthal JW, Wano Y, Franza BR, Greene WC. PMID: 2843985.
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    238. p55 IL-2 receptor mRNA precursors in murine T lymphocyte nuclei. J Immunol. 1988 Aug 15; 141(4):1358-64. Froussard P, Chastagner P, Sommé G, Abadie A, Greene W, Thèze J, Longacre S. PMID: 3135330.
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    239. The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV. Cell. 1988 Jun 03; 53(5):827-36. Böhnlein E, Lowenthal JW, Siekevitz M, Ballard DW, Franza BR, Greene WC. PMID: 2836068.
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    240. Regulation of interleukin 2 receptor alpha subunit (Tac or CD25 antigen) gene expression: binding of inducible nuclear proteins to discrete promoter sequences correlates with transcriptional activation. Proc Natl Acad Sci U S A. 1988 Jun; 85(12):4468-72. Lowenthal JW, Böhnlein E, Ballard DW, Greene WC. PMID: 3132714.
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    241. Sequence requirements for ligand binding and cell surface expression of the Tac antigen, a human interleukin-2 receptor. J Biol Chem. 1988 Apr 05; 263(10):4900-6. Cullen BR, Podlaski FJ, Peffer NJ, Hosking JB, Greene WC. PMID: 2832410.
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    242. Sarcoidosis and interleukin-2 receptors. Am Rev Respir Dis. 1988 Apr; 137(4):757-8. Greene WC. PMID: 2833139.
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    243. Lymphocytes isolated from the intestinal lamina propria of normal nonhuman primates have increased expression of genes associated with T-cell activation. Gastroenterology. 1988 Mar; 94(3):647-55. Zeitz M, Greene WC, Peffer NJ, James SP. PMID: 3123303.
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    244. The human interleukin-2 receptor. Recent studies of structure and regulation. Ann N Y Acad Sci. 1988; 546:116-21. Greene WC, Böhnlein E, Siekevitz M, Franza BR, Lowenthal J. PMID: 3073691.
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    245. Novel interleukin 2 (IL-2) receptor appears to mediate IL-2-induced activation of natural killer cells. J Clin Invest. 1988 Jan; 81(1):200-5. Kehrl JH, Dukovich M, Whalen G, Katz P, Fauci AS, Greene WC. PMID: 2826541.
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    246. In: Smith KA (Ed.), Interleukin 2. New perspectives on the structure of the human high affinity i nterleukin-2 receptor. 1988; 99-112. Wano Y, Dukovich M, Kehrl JH, Greene WC..
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    248. In: Gallin J, Goldstein I, Snyderman R (Eds.), Inflammation: Basic principles and clinical correlations. IL-2, IL-2 receptors, and the growth of human T cells. 1988; 209-288. Greene WC..
    249. Activation of the HIV-1 LTR by T cell mitogens and the trans-activator protein of HTLV-I. Science. 1987 Dec 11; 238(4833):1575-8. Siekevitz M, Josephs SF, Dukovich M, Peffer N, Wong-Staal F, Greene WC. PMID: 2825351.
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    250. Contrasting interleukin 2 binding properties of the alpha (p55) and beta (p70) protein subunits of the human high-affinity interleukin 2 receptor. J Exp Med. 1987 Oct 01; 166(4):1156-61. Lowenthal JW, Greene WC. PMID: 3116145.
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    251. Reconstitution of a functional interleukin 2 receptor in a nonlymphoid cell. J Immunol. 1987 Oct 01; 139(7):2355-60. Rubin LA, Hoekzema GS, Nelson DL, Greene WC, Jay G. PMID: 2821112.
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    252. Direct activation of human resting T cells by IL 2: the role of an IL 2 receptor distinct from the Tac protein. J Immunol. 1987 Sep 01; 139(5):1550-6. Bich-Thuy LT, Dukovich M, Peffer NJ, Fauci AS, Kehrl JH, Greene WC. PMID: 3040856.
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    253. Interleukin 1 gene expression in adult T cell leukemia. J Clin Invest. 1987 Sep; 80(3):911-6. Wano Y, Hattori T, Matsuoka M, Takatsuki K, Chua AO, Gubler U, Greene WC. PMID: 2887587.
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    254. The human interleukin-2 receptor: a molecular and biochemical analysis of structure and function. Clin Res. 1987 Sep; 35(5):439-50. Greene WC. PMID: 2889557.
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    255. Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I. Proc Natl Acad Sci U S A. 1987 Aug; 84(15):5389-93. Siekevitz M, Feinberg MB, Holbrook N, Wong-Staal F, Greene WC. PMID: 3037548.
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    256. A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors. Nature. 1987 Jun 11-17; 327(6122):518-22. Dukovich M, Wano Y, Katz P, Cullen BR, Kehrl JH, Greene WC. PMID: 3108674.
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    257. Expression of functional IL 2 receptors by lipopolysaccharide and interferon-gamma stimulated human monocytes. J Immunol. 1987 May 01; 138(9):2917-22. Holter W, Goldman CK, Casabo L, Nelson DL, Greene WC, Waldmann TA. PMID: 3106493.
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    258. Internalization of interleukin 2 is mediated by the beta chain of the high-affinity interleukin 2 receptor. J Exp Med. 1987 Apr 01; 165(4):1201-6. Robb RJ, Greene WC. PMID: 3031195.
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    259. Interleukin 2 binding molecule distinct from the Tac protein: analysis of its role in formation of high-affinity receptors. Proc Natl Acad Sci U S A. 1987 Apr; 84(7):2002-6. Robb RJ, Rusk CM, Yodoi J, Greene WC. PMID: 3031660.
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    260. High-affinity interleukin 2 binding by an oncogenic hybrid interleukin 2-epidermal growth factor receptor molecule. Proc Natl Acad Sci U S A. 1987 Apr; 84(8):2125-9. Bernard O, Fazekas de St Groth B, Ullrich A, Green W, Schlessinger J. PMID: 3104909.
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    261. Reconstitution of high affinity IL-2 receptor expression in a human T-cell line using a retroviral cDNA expression vector. Mol Biol Med. 1987 Apr; 4(2):95-109. Wano Y, Cullen BR, Svetlik PA, Peffer NJ, Greene WC. PMID: 3114593.
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    262. Trans-activator gene of HTLV-II: interpretation. Science. 1987 Feb 27; 235(4792):1073. Greene WC, Leonard WJ, Wano Y, Svetlik PB, Peffer NJ, Sodroski JG, Rosen CA, Goh WC, Haseltine WA. PMID: 3029865.
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    269. Expression of human interleukin-2 receptor cDNA in E. coli. Biochem Biophys Res Commun. 1986 Dec 15; 141(2):804-11. Chanda PK, Chen GF, Baine Y, Leonard WJ, Greene WC, Chang TW, Chang NT. PMID: 3026392.
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    270. Diltiazem inhibits transferrin receptor expression and causes G1 arrest in normal and neoplastic T cells. Mol Cell Biol. 1986 Dec; 6(12):4244-50. Neckers LM, Bauer S, McGlennen RC, Trepel JB, Rao K, Greene WC. PMID: 2432398.
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    273. Selective killing of human T-lymphotropic virus-I infected leukemic T-cells by monoclonal anti-interleukin 2 receptor antibody-ricin A chain conjugates: potentiation by ammonium chloride and monensin. Cancer Res. 1986 Jul; 46(7):3295-8. Krönke M, Schlick E, Waldmann TA, Vitetta ES, Greene WC. PMID: 3011246.
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    293. Adult T cell leukemia: a potential target for ricin A chain immunotoxins. Blood. 1985 Jun; 65(6):1416-21. Krönke M, Depper JM, Leonard WJ, Vitetta ES, Waldmann TA, Greene WC. PMID: 2986744.
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    294. Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene. Proc Natl Acad Sci U S A. 1985 Jun; 82(12):4230-4. Depper JM, Leonard WJ, Drogula C, Krönke M, Waldmann TA, Greene WC. PMID: 2987968.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansCells
    295. Sequential expression of genes involved in human T lymphocyte growth and differentiation. J Exp Med. 1985 Jun 01; 161(6):1593-8. Krönke M, Leonard WJ, Depper JM, Greene WC. PMID: 2989408.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCells
    296. Nucleotide sequence and expression of a mouse interleukin 2 receptor cDNA. J Immunol. 1985 Jun; 134(6):4212-7. Miller J, Malek TR, Leonard WJ, Greene WC, Shevach EM, Germain RN. PMID: 3921620.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    297. The human receptor for T-cell growth factor. Evidence for variable post-translational processing, phosphorylation, sulfation, and the ability of precursor forms of the receptor to bind T-cell growth factor. J Biol Chem. 1985 Feb 10; 260(3):1872-80. Leonard WJ, Depper JM, Krönke M, Robb RJ, Waldmann TA, Greene WC. PMID: 2981876.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    298. The human interleukin-2 receptor. J Cell Sci Suppl. 1985; 3:97-106. Greene WC, Depper JM, Krönke M, Leonard WJ. PMID: 3938983.
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    299. Activators of protein kinase C and 5-azacytidine induce IL-2 receptor expression on human T lymphocytes. J Cell Biochem. 1985; 27(3):267-76. Depper JM, Leonard WJ, Drogula CL, Krönke M, Waldmann TA, Greene WC. PMID: 2580852.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    300. Molecular cloning of cDNA for the human interleukin-2 receptor. Haematol Blood Transfus. 1985; 29:388-95. Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik P, Peffer NJ, Waldmann TA. PMID: 2993133.
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    301. Receptors for T-cell growth factor: structure, function and expression on normal and neoplastic cells. Contemp Top Mol Immunol. 1985; 10:1-34. Greene WC, Robb RJ. PMID: 2983931.
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    302. In: Sorg C, Schimple A (Eds.), Cellular and molecular biology of lymphokines. Cloning of cDNAs for the human interleukin-2 receptor and determination of its complete protein sequence. 1985; 623-633. Leonard WJ, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Kronke M, Svetlik P, Peffer NJ, Waldmann TA, Greene WC..
    303. In: Sorg C, Schimple A (Eds.), Cellular and molecular biology of lymphokines. Cyclosporin A inhibits expression of select T-cell activation genes. 1985; 647-652. Kronke M, Depper JM, Leonard WJ, Wong-Staal F, Gallo RC, Waldmann TA, Greene WC..
    304. In: Sorg P, Schimple A (Eds.), Cellular and molecular biology of lymphokines. The role of protein kinase C, and effects of 5-azacytidine on regulation on interleukin-2 receptor expression. 1985; 151-156. Depper JM, Leonard WJ, Kronke M, Waldmann TA, Greene WC..
    305. In: Cancer Cells 3: Growth factors and transformation. Structure, function, and expression of the receptor for interleukin-2 on normal and malignant lymphocytes. 1985; 221-226. Waldmann TA, Leonard WJ, Depper JM, Kronke M, Kozak R, Greene WC..
    306. In: Pattengale PK, Lukes RJ, Taylor CR (Eds.), Lymphoproliferative Diseases: Pathogenesis, Diagnosis, and Therapy. Molecular analysis of the human interleukin-2 receptor. 1985; 8-20. Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Kronke M, Svetlik P, Peffer NJ, Waldmann TA, Leonard WJ.
    307. Effect of wheat germ agglutinin on the interleukin pathway of human T lymphocyte activation. J Immunol. 1985 Jan; 134(1):314-23. Reed JC, Robb RJ, Greene WC, Nowell PC. PMID: 3917278.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    308. In: Feldman M (Ed.), Human T cell clones: An approach to immune regulation. Interleukin-2 receptors. 1985; 285-300. Waldmann TA, Leonard WJ, Depper JM, Kronke M, Goldman CK, Bongiovani KF, Greene WC..
    309. In: Feldmann M, Mitchison NA (Eds.), Immune Regulation. Molecular cloning and expression of cDNAs encoding the human interleukin-2 receptor. 1985; 185-195. Leonard WJ, Depper JM, Crabtee GM, Rudikoff S, Pumphrey J, Robb RJ, Kronke M, Svetlik P, Peffer NJ, Waldmann TA, Greene WC..
    310. In: Pinchera A, Doria G, Dammacco F, Bargellesi A (Eds.), Monoclonal Antibodies 1984: Biological and Clinical Applications. Interleukin-2 receptors on lymphocytes. 1985; 329-338. Waldmann TA, Leonard WJ, Depper JM, Kronke M, Goldman CK, Sharrow S, Greene WC..
    311. Regulation of interleukin 2 receptor expression: effects of phorbol diester, phospholipase C, and reexposure to lectin or antigen. J Immunol. 1984 Dec; 133(6):3054-61. Depper JM, Leonard WJ, Krönke M, Noguchi PD, Cunningham RE, Waldmann TA, Greene WC. PMID: 6092466.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    312. Cellular origin of hairy cell leukemia: malignant B cells that express receptors for T cell growth factor. Semin Oncol. 1984 Dec; 11(4):394-400. Korsmeyer SJ, Greene WC, Waldmann TA. PMID: 6438801.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    313. Expression of interleukin 2 receptors on activated human B cells. J Exp Med. 1984 Nov 01; 160(5):1450-66. Waldmann TA, Goldman CK, Robb RJ, Depper JM, Leonard WJ, Sharrow SO, Bongiovanni KF, Korsmeyer SJ, Greene WC. PMID: 6092511.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansCells
    314. Augmented T cell growth factor receptor expression in HTLV-1-infected human leukemic T cells. J Immunol. 1984 Oct; 133(4):1691-5. Depper JM, Leonard WJ, Krönke M, Waldmann TA, Greene WC. PMID: 6088625.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    315. Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen. J Exp Med. 1984 Oct 01; 160(4):1126-46. Robb RJ, Greene WC, Rusk CM. PMID: 6090574.
      View in: PubMed   Mentions: 192     Fields:    Translation:HumansAnimalsCells
    316. Molecular cloning and expression of cDNAs for the human interleukin-2 receptor. Nature. 1984 Oct 18-24; 311(5987):626-31. Leonard WJ, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik PB, Peffer NJ, Waldmann TA. PMID: 6090948.
      View in: PubMed   Mentions: 196     Fields:    Translation:HumansCells
    317. Phorbol diester induces expression of Tac antigen on human acute T lymphocytic leukemic cells. J Immunol. 1984 Aug; 133(2):1042-7. Greene WC, Robb RJ, Depper JM, Leonard WJ, Drogula C, Svetlik PB, Wong-Staal F, Gallo RC, Waldmann TA. PMID: 6330200.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    318. Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription. Proc Natl Acad Sci U S A. 1984 Aug; 81(16):5214-8. Krönke M, Leonard WJ, Depper JM, Arya SK, Wong-Staal F, Gallo RC, Waldmann TA, Greene WC. PMID: 6332315.
      View in: PubMed   Mentions: 141     Fields:    Translation:HumansCells
    319. Functional and phenotypic comparison of human T cell leukemia/lymphoma virus positive adult T cell leukemia with human T cell leukemia/lymphoma virus negative Sézary leukemia, and their distinction using anti-Tac. Monoclonal antibody identifying the human receptor for T cell growth factor. J Clin Invest. 1984 Jun; 73(6):1711-8. Waldmann TA, Greene WC, Sarin PS, Saxinger C, Blayney DW, Blattner WA, Goldman CK, Bongiovanni K, Sharrow S, Depper JM. PMID: 6327770.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    320. Expression of receptors for interleukin 2: Role in the commitment of T lymphocytes to proliferate. J Immunol. 1984 Jan; 132(1):31-7. Lipkowitz S, Greene WC, Rubin AL, Novogrodsky A, Stenzel KH. PMID: 6418801.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    321. Interleukin-2 receptor expression in retrovirus associated adult T-cell leukemia. Princess Takamatsu Symp. 1984; 15:259-68. Waldmann TA, Leonard WJ, Depper JM, Krönke M, Goldman CK, Oh T, Greene WC. PMID: 6100644.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    322. In: Pick E (Ed.), Lymphokines. A monoclonal antibody which recognizes the human receptor for T cell growth factor: Functional effects and use as a probe to investigate receptor regulation. 1984; 9:127-152. Depper JM, Leonard WJ, Waldmann TA, Greene WC..
    323. In: Greaves M (Ed.), Receptors and Recognition. A monoclonal antibody to the human receptor for T cell growth factor. 1984; 17:45-66. Leonard WJ, Depper JM, Waldmann TA, Greene WC..
    324. In: Sasazuki T (Ed.), Immunogenetics: Its application to clinical medicine. Cell-cell interactions in the human immune response: Analysis of leukemic T calls with immunoregulatory functions. 1984; 137-142. Waldmann TA, Broder S, Greene WC..
    325. Interleukin-2 receptors on activated malignant and normal B-cells. Curr Top Microbiol Immunol. 1984; 113:96-101. Waldmann TA, Goldman CK, Leonard WJ, Depper JM, Robb RJ, Korsmeyer SJ, Greene WC. PMID: 6236954.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    326. Monoclonal lupus autoantibody secretion by human-human hybridomas. Selection of hybrids by conventional and novel techniques. J Clin Invest. 1983 Dec; 72(6):1987-94. Littman BH, Muchmore AV, Steinberg AD, Greene WC. PMID: 6605979.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    327. Characterization of the human receptor for T-cell growth factor. Proc Natl Acad Sci U S A. 1983 Nov; 80(22):6957-61. Leonard WJ, Depper JM, Robb RJ, Waldmann TA, Greene WC. PMID: 6417659.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    328. Direct demonstration of the identity of T cell growth factor binding protein and the Tac antigen. J Exp Med. 1983 Oct 01; 158(4):1332-7. Robb RJ, Greene WC. PMID: 6413637.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    329. Association of human T-cell leukaemia/lymphoma virus with the Tac antigen marker for the human T-cell growth factor receptor. Nature. 1983 Oct 20-26; 305(5936):733-6. Lando Z, Sarin P, Megson M, Greene WC, Waldman TA, Gallo RC, Broder S. PMID: 6195529.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    330. Blockade of the interleukin-2 receptor by anti-Tac antibody: inhibition of human lymphocyte activation. J Immunol. 1983 Aug; 131(2):690-6. Depper JM, Leonard WJ, Robb RJ, Waldmann TA, Greene WC. PMID: 6408186.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    331. Rearrangement and expression of immunoglobulin genes and expression of Tac antigen in hairy cell leukemia. Proc Natl Acad Sci U S A. 1983 Jul; 80(14):4522-6. Korsmeyer SJ, Greene WC, Cossman J, Hsu SM, Jensen JP, Neckers LM, Marshall SL, Bakhshi A, Depper JM, Leonard WJ, Jaffe ES, Waldmann TA. PMID: 6192435.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    332. Evidence for an interleukin-independent pathway for human lymphocyte activation. Proc Natl Acad Sci U S A. 1983 Jun; 80(11):3444-7. Koretzky GA, Daniele RP, Greene WC, Nowell PC. PMID: 6407014.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    333. Polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen. J Exp Med. 1983 Mar 01; 157(3):1064-9. Cossman J, Neckers LM, Leonard WJ, Greene WC. PMID: 6220104.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    334. Construction of human suppressor T cell hybridomas. Lymphokine Res. 1983; 2(2):53-60. Greene WC, Depper JM, Leonard WJ, Fleisher TA, Waldmann TA. PMID: 6236341.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    335. In: Golde DW, Marks PA (Eds.), Normal and Neoplastic Hematopoiesis, UCLA Symposia on Molecular and Cellular Biology. Hairy cell leukemia: A malignant expansion of B cells that express Tac antigen. 1983; 9:491-500. Greene WC, Cossman J, Leonard WJ, Bakshi A, Waldmann TA, Korsmeyer SJ.
    336. The role of cell surface lectin--carbohydrate interactions in cellular recognition, cooperation, and regulation. Am J Pediatr Hematol Oncol. 1983; 5(2):199-206. Blaese RM, Tosato G, Greene WC, Fleisher TA, Muchmore AV. PMID: 6193722.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    337. A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor. Nature. 1982 Nov 18; 300(5889):267-9. Leonard WJ, Depper JM, Uchiyama T, Smith KA, Waldmann TA, Greene WC. PMID: 6815536.
      View in: PubMed   Mentions: 206     Fields:    Translation:Humans
    338. Production of human suppressor T cell hybridomas. J Immunol. 1982 Nov; 129(5):1986-92. Greene WC, Fleisher TA, Nelson DL, Waldmann TA. PMID: 6214585.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    339. Interferon-mediated inhibition of human polyclonal immunoglobulin synthesis. J Immunol. 1982 Sep; 129(3):1099-103. Fleisher TA, Attallah AM, Tosato G, Blaese RM, Greene WC. PMID: 6179992.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    340. Characterization of a soluble suppressor of human B cell function produced by a continuous human suppressor T cell line. II. Evidence for suppression through a direct action of CTC-SISS-B on human B cells. J Immunol. 1982 Sep; 129(3):1120-3. Greene WC, Fleisher TA, Depper JM, Leonard WJ, Stanton GJ, Waldmann TA. PMID: 6213708.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    341. In: Oppenheim JJ, Cohen S (Eds.), Interleukins, lymphokines, and cytokines. Monoclonal anti-Tac blocks the action of human interleukin-2. 1982; 19-24. Depper JM, Leonard WJ, Smith KA, Waldmann TA, Greene WC..
    342. Stimulation of immunoglobulin biosynthesis in human B cells by wheat germ agglutinin. I. Evidence that WGA can produce both a positive and negative signal for activation of human lymphocytes. J Immunol. 1981 Aug; 127(2):799-804. Greene WC, Goldman CK, Marshall ST, Fleisher TA, Waldmann TA. PMID: 6265558.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    343. Characterization of a soluble suppressor of human B cell immunoglobulin biosynthesis produced by a continuous human suppressor T cell line. J Exp Med. 1981 Jul 01; 154(1):156-67. Fleisher TA, Greene WC, Uchiyama T, Goldman CK, Nelson DL, Blaese RM, Waldmann TA. PMID: 6454754.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    344. Soluble suppressor supernatants elaborated by concanavalin A-activated human mononuclear cells. I. Characterization of a soluble suppressor T cell proliferation. J Immunol. 1981 Mar; 126(3):1185-91. Greene WC, Fleisher TA, Waldmann TA. PMID: 6450803.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    345. Soluble suppressor supernatants elaborated by concanavalin A-activated human mononuclear cells. II. Characterization of a soluble suppressor of B cell immunoglobulin production. J Immunol. 1981 Mar; 126(3):1192-7. Fleisher TA, Greene WC, Blaese RM, Waldmann TA. PMID: 6450804.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    346. Suppression of human T and B lymphocyte activation by Agaricus bisporus lectin. I. Suggestive evidence for a surface "suppressor" receptor in human lymphocytes. J Immunol. 1981 Feb; 126(2):580-6. Greene WC, Fleisher TA, Waldmann TA. PMID: 6778919.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    347. Inhibition of human lymphocyte proliferation by the nonmitogenic lectin wheat germ agglutinin. J Immunol. 1980 Jun; 124(6):2979-87. Greene WC, Waldmann TA. PMID: 6966300.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    348. In: Cramer H, Schultz J (Eds.), Mechanism of Action. Cyclic nucleotides in the immune response. 1977; 161-187. Parker CW, Greene WC..
    349. Cytochalasin sensitive structures and lymphocyte activation. Exp Cell Res. 1976 Nov; 103(1):109-17. Greene WC, Parker CM, Parker CW. PMID: 186286.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    350. Cytochalasin binding in lymphocytes and polymorphonuclear leukocytes. Exp Cell Res. 1976 Nov; 103(1):99-108. Parker CW, Greene WC, MacDonald HH. PMID: 991953.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    351. Colchicine-sensitive structures and lymphocyte activation. J Immunol. 1976 Sep; 117(3):1015-22. Greene WC, Parker CM, Parker CW. PMID: 956646.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    352. Opposing effects of mitogenic and nonmitogenic lectins on lymphocyte activation. Evidence that wheat germ agglutinin produces a negative signal. J Biol Chem. 1976 Jul 10; 251(13):4017-25. Greene WC, Parker CM, Parker CW. PMID: 932019.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    353. Calcium and lymphocyte activation. Cell Immunol. 1976 Jul; 25(1):74-89. Greene WC, Parker CM, Parker CW. PMID: 183895.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    354. Studies on the stimulation of cAMP metabolism in human lymphocytes by latex polymers. Exp Cell Res. 1976 May; 99(2):395-407. Atkinson JP, Greene WC, McNearney TA, Parker CW. PMID: 178514.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    355. Suggestive evidence for both stimulatory and inhibitory domains on human lymphocytes, as indicated by phospholipid turnover studies with wheat germ agglutinin and other lectins. Immunol Commun. 1976; 5(1-2):13-25. Parker CW, Dankner RE, Falkenhein SF, Greene WC. PMID: 181319.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    356. In: Eijsvoogel W, Roos D, Zeijlemaker WP (Eds.), Leukocyte membrane determinants regulating immune reactivity. Calcium ionophore A23187 and lymphocyte activation. 1976; 10:129. Greene WC, Wedner HJ, Parker CW.
    357. A role for cytochalasin-sensitive proteins in the regulation of calcium transport in activated human lymphocytes. Biochem Biophys Res Commun. 1975 Jul 22; 65(2):456-63. Greene WC, Parker CW. PMID: 167774.
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    358. Concanavalin A-induced histamine release from normal rat mast cells. J Immunol. 1975 Jul; 115(1):278-82. Sullivan TJ, Greene WC, Parker CW. PMID: 50352.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    359. Effect of experimental diabetes mellitus on kidney ribosomal protein synthesis. Diabetes. 1971 Oct; 20(10):649-54. Peterson DT, Greene WC, Reaven GM. PMID: 5110696.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
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