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Fibrin drives thromboinflammation and neuropathology in COVID-19. Nature. 2024 Sep; 633(8031):905-913.
Ryu JK, Yan Z, Montano M, Sozmen EG, Dixit K, Suryawanshi RK, Matsui Y, Helmy E, Kaushal P, Makanani SK, Deerinck TJ, Meyer-Franke A, Rios Coronado PE, Trevino TN, Shin MG, Tognatta R, Liu Y, Schuck R, Le L, Miyajima H, Mendiola AS, Arun N, Guo B, Taha TY, Agrawal A, MacDonald E, Aries O, Yan A, Weaver O, Petersen MA, Meza Acevedo R, Alzamora MDPS, Thomas R, Traglia M, Kouznetsova VL, Tsigelny IF, Pico AR, Red-Horse K, Ellisman MH, Krogan NJ, Bouhaddou M, Ott M, Greene WC, Akassoglou K. PMID: 39198643; PMCID: PMC11424477.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Neutralizing and binding antibody responses to SARS-CoV-2 with hybrid immunity in pregnancy. NPJ Vaccines. 2024 Aug 27; 9(1):156.
Li L, Matsui Y, Prahl MK, Cassidy AG, Golan Y, Jigmeddagva U, Ozarslan N, Lin CY, Buarpung S, Gonzalez VJ, Chidboy MA, Basilio E, Lynch KL, Song D, Jegatheesan P, Rai DS, Govindaswami B, Needens J, Rincon M, Myatt L, Taha TY, Montano M, Ott M, Greene WC, Gaw SL. PMID: 39191763; PMCID: PMC11349990.
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PubMed Mentions:
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Neuroinflammation generated by HIV-infected microglia promotes dysfunction and death of neurons in human brain organoids. PNAS Nexus. 2024 May; 3(5):pgae179.
Kong W, Frouard J, Xie G, Corley MJ, Helmy E, Zhang G, Schwarzer R, Montano M, Sohn P, Roan NR, Ndhlovu LC, Gan L, Greene WC. PMID: 38737767; PMCID: PMC11086946.
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PubMed Mentions:
4
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Comprehensive synergy mapping links a BAF- and NSL-containing "supercomplex" to the transcriptional silencing of HIV-1. Cell Rep. 2023 Sep 26; 42(9):113055.
Li Z, Deeks SG, Ott M, Greene WC. PMID: 37682714; PMCID: PMC10591912.
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PubMed Mentions:
1 Fields:
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Neuropilin-1 Mediates SARS-CoV-2 Infection of Astrocytes in Brain Organoids, Inducing Inflammation Leading to Dysfunction and Death of Neurons. mBio. 2022 12 20; 13(6):e0230822.
Kong W, Montano M, Corley MJ, Helmy E, Kobayashi H, Kinisu M, Suryawanshi R, Luo X, Royer LA, Roan NR, Ott M, Ndhlovu LC, Greene WC. PMID: 36314791; PMCID: PMC9765283.
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PubMed Mentions:
36 Fields:
Translation:
HumansCells
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SARS-CoV-2 can infect human embryos. Sci Rep. 2022 09 14; 12(1):15451.
Montano M, Victor AR, Griffin DK, Duong T, Bolduc N, Farmer A, Garg V, Hadjantonakis AK, Coates A, Barnes FL, Zouves CG, Greene WC, Viotti M. PMID: 36104397; PMCID: PMC9472724.
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PubMed Mentions:
7 Fields:
Translation:
HumansCellsPHPublic Health
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CCL2: a Chemokine Potentially Promoting Early Seeding of the Latent HIV Reservoir. mBio. 2022 10 26; 13(5):e0189122.
Packard TA, Schwarzer R, Herzig E, Rao D, Luo X, Egedal JH, Hsiao F, Widera M, Hultquist JF, Grimmett ZW, Messer RJ, Krogan NJ, Deeks SG, Roan NR, Dittmer U, Hasenkrug KJ, Greene WC. PMID: 36073812; PMCID: PMC9600577.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Female Genital Fibroblasts Diminish the In Vitro Efficacy of PrEP against HIV. Viruses. 2022 08 04; 14(8).
George AF, McGregor M, Gingrich D, Neidleman J, Marquez RS, Young KC, Thanigaivelan KL, Greene WC, Tien PC, Deitchman AN, Spitzer TL, Roan NR. PMID: 36016345; PMCID: PMC9413545.
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Translation:
HumansCells
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Infectious Diseases Institute at Makerere University College of Health Sciences: a case study of a sustainable capacity building model for health care, research and training. Afr Health Sci. 2022 Aug; 22(Spec Issue):1-10.
Nakanjako D, Castelnuovo B, Sewankambo N, Kakaire T, Brough RL, Katabira ET, Thomas DL, Quinn TC, Colebunders R, Greene WC, Ronald AR, Coutinho A, McAdam K, Serwadda D, Wabwire-Mangen F, Katongole-Mbidde E, Musoke P, Joloba M, McKinnell H, Kamya M, Mayanja-Kizza H, Manabe YC, Kambugu A. PMID: 36321127; PMCID: PMC9590334.
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PubMed Mentions:
2 Fields:
Translation:
HumansPHPublic Health
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Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and infancy. Nat Commun. 2022 07 30; 13(1):4422.
Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J, Gaw SL. PMID: 35908075; PMCID: PMC9338928.
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PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Neutralizing antibody activity against SARS-CoV-2 variants in gestational age-matched mother-infant dyads after infection or vaccination. JCI Insight. 2022 06 22; 7(12).
Matsui Y, Li L, Prahl M, Cassidy AG, Ozarslan N, Golan Y, Gonzalez VJ, Lin CY, Jigmeddagva U, Chidboy MA, Montano M, Taha TY, Khalid MM, Sreekumar B, Hayashi JM, Chen PY, Kumar GR, Warrier L, Wu AH, Song D, Jegatheesan P, Rai DS, Govindaswami B, Needens J, Rincon M, Myatt L, Asiodu IV, Flaherman VJ, Afshar Y, Jacoby VL, Murtha AP, Robinson JF, Ott M, Greene WC, Gaw SL. PMID: 35579965; PMCID: PMC9309042.
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PubMed Mentions:
13 Fields:
Translation:
HumansCellsPHPublic Health
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Subsets of Tissue CD4 T Cells Display Different Susceptibilities to HIV Infection and Death: Analysis by CyTOF and Single Cell RNA-seq. Front Immunol. 2022; 13:883420.
Luo X, Frouard J, Zhang G, Neidleman J, Xie G, Sheedy E, Roan NR, Greene WC. PMID: 35784348; PMCID: PMC9245423.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination. Nature. 2022 07; 607(7918):351-355.
Suryawanshi RK, Chen IP, Ma T, Syed AM, Brazer N, Saldhi P, Simoneau CR, Ciling A, Khalid MM, Sreekumar B, Chen PY, Kumar GR, Montano M, Gascon R, Tsou CL, Garcia-Knight MA, Sotomayor-Gonzalez A, Servellita V, Gliwa A, Nguyen J, Silva I, Milbes B, Kojima N, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Soveg FW, George AF, Fang X, Maishan M, Matthay M, Morris MK, Wadford D, Hanson C, Greene WC, Andino R, Spraggon L, Roan NR, Chiu CY, Doudna JA, Ott M. PMID: 35584773; PMCID: PMC9279157.
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Limited Cross-Variant Immunity after Infection with the SARS-CoV-2 Omicron Variant Without Vaccination. medRxiv. 2022 Feb 09.
Suryawanshi RK, Chen IP, Ma T, Syed AM, Brazer N, Saldhi P, Simoneau CR, Ciling A, Khalid MM, Sreekumar B, Chen PY, Kumar GR, Montano M, Garcia-Knight MA, Sotomayor-Gonzalez A, Servellita V, Gliwa A, Nguyen J, Silva I, Milbes B, Kojima N, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Soveg FW, George AF, Fang X, Maishan M, Matthay M, Greene WC, Andino R, Spraggon L, Roan NR, Chiu CY, Doudna J, Ott M. PMID: 35075459; PMCID: PMC8786226.
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Deep Phenotypic Analysis of Blood and Lymphoid T and NK Cells From HIV+ Controllers and ART-Suppressed Individuals. Front Immunol. 2022; 13:803417.
George AF, Luo X, Neidleman J, Hoh R, Vohra P, Thomas R, Shin MG, Lee MJ, Blish CA, Deeks SG, Greene WC, Lee SA, Roan NR. PMID: 35154118; PMCID: PMC8829545.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy. Res Sq. 2021 Dec 15.
Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J, Gaw SL. PMID: 34931183; PMCID: PMC8687466.
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PubMed Mentions:
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Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy. medRxiv. 2021 Dec 13.
Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J, Gaw SL. PMID: 34931197; PMCID: PMC8687468.
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PubMed Mentions:
3
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Cell-Extrinsic Priming Increases Permissiveness of CD4+ T Cells to Human Immunodeficiency Virus Infection by Increasing C-C Chemokine Receptor Type 5 Co-receptor Expression and Cellular Activation Status. Front Microbiol. 2021; 12:763030.
Pedersen JG, Egedal JH, Packard TA, Thavachelvam K, Xie G, van der Sluis RM, Greene WC, Roan NR, Jakobsen MR. PMID: 34899645; PMCID: PMC8661899.
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SARS-CoV-2 spike protein induces abnormal inflammatory blood clots neutralized by fibrin immunotherapy. bioRxiv. 2021 Oct 13.
Ryu JK, Sozmen EG, Dixit K, Montano M, Matsui Y, Liu Y, Helmy E, Deerinck TJ, Yan Z, Schuck R, Acevedo RM, Spencer CM, Thomas R, Pico AR, Zamvil SS, Lynch KL, Ellisman MH, Greene WC, Akassoglou K. PMID: 34671772; PMCID: PMC8528086.
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PubMed Mentions:
1
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mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status. Elife. 2021 10 12; 10.
Neidleman J, Luo X, McGregor M, Xie G, Murray V, Greene WC, Lee SA, Roan NR. PMID: 34636722; PMCID: PMC8545397.
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PubMed Mentions:
52 Fields:
Translation:
HumansCellsPHPublic Health
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Bystander CD4 T-cell death is inhibited by broadly neutralizing anti-HIV antibodies only at levels blocking cell-to-cell viral transmission. J Biol Chem. 2021 10; 297(4):101098.
Luo X, Mouquet H, Schwartz O, Greene WC. PMID: 34418431; PMCID: PMC8446805.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status. bioRxiv. 2021 Jul 29.
Neidleman J, Luo X, McGregor M, Xie G, Murray V, Greene WC, Lee SA, Roan NR. PMID: 34013277; PMCID: PMC8132283.
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PubMed Mentions:
1
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Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19. Cell Rep. 2021 07 20; 36(3):109414.
Neidleman J, Luo X, George AF, McGregor M, Yang J, Yun C, Murray V, Gill G, Greene WC, Vasquez J, Lee SA, Ghosn E, Lynch KL, Roan NR. PMID: 34260965; PMCID: PMC8238659.
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PubMed Mentions:
54 Fields:
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Hyaluronic acid is a negative regulator of mucosal fibroblast-mediated enhancement of HIV infection. Mucosal Immunol. 2021 09; 14(5):1203-1213.
Egedal JH, Xie G, Packard TA, Laustsen A, Neidleman J, Georgiou K, Pillai SK, Greene WC, Jakobsen MR, Roan NR. PMID: 33976386; PMCID: PMC8379073.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Characterization of HIV-induced remodeling reveals differences in infection susceptibility of memory CD4+ T cell subsets in vivo. Cell Rep. 2021 04 27; 35(4):109038.
Xie G, Luo X, Ma T, Frouard J, Neidleman J, Hoh R, Deeks SG, Greene WC, Roan NR. PMID: 33910003; PMCID: PMC8202093.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19. medRxiv. 2021 Feb 05.
Neidleman J, Luo X, George AF, McGregor M, Yang J, Yun C, Murray V, Gill G, Greene WC, Vasquez J, Lee S, Ghosn E, Lynch K, Roan NR. PMID: 33532792; PMCID: PMC7852243.
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Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity Ex Vivo and In Vivo. J Virol. 2021 03 25; 95(8).
Gramatica A, Schwarzer R, Brantley W, Varco-Merth B, Sperber HS, Hull PA, Montano M, Migueles SA, Rosenthal D, Hogan LE, Johnson JR, Packard TA, Grimmett ZW, Herzig E, Besnard E, Nekorchuk M, Hsiao F, Deeks SG, Snape M, Kiernan B, Roan NR, Lifson JD, Estes JD, Picker LJ, Verdin E, Krogan NJ, Henrich TJ, Connors M, Ott M, Pillai SK, Okoye AA, Greene WC. PMID: 33536176; PMCID: PMC8103695.
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PubMed Mentions:
9 Fields:
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Identification of unrecognized host factors promoting HIV-1 latency. PLoS Pathog. 2020 12; 16(12):e1009055.
Li Z, Hajian C, Greene WC. PMID: 33270809; PMCID: PMC7714144.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Human splice factors contribute to latent HIV infection in primary cell models and blood CD4+ T cells from ART-treated individuals. PLoS Pathog. 2020 11; 16(11):e1009060.
Moron-Lopez S, Telwatte S, Sarabia I, Battivelli E, Montano M, Macedo AB, Aran D, Butte AJ, Jones RB, Bosque A, Verdin E, Greene WC, Wong JK, Yukl SA. PMID: 33253324; PMCID: PMC7728277.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir. Elife. 2020 09 29; 9.
Neidleman J, Luo X, Frouard J, Xie G, Hsiao F, Ma T, Morcilla V, Lee A, Telwatte S, Thomas R, Tamaki W, Wheeler B, Hoh R, Somsouk M, Vohra P, Milush J, James KS, Archin NM, Hunt PW, Deeks SG, Yukl SA, Palmer S, Greene WC, Roan NR. PMID: 32990219; PMCID: PMC7524554.
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PubMed Mentions:
50 Fields:
Translation:
HumansCells
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SARS-CoV-2-Specific T Cells Exhibit Phenotypic Features of Helper Function, Lack of Terminal Differentiation, and High Proliferation Potential. Cell Rep Med. 2020 09 22; 1(6):100081.
Neidleman J, Luo X, Frouard J, Xie G, Gill G, Stein ES, McGregor M, Ma T, George AF, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR. PMID: 32839763; PMCID: PMC7437502.
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PubMed Mentions:
133 Fields:
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SARS-CoV-2-specific T cells exhibit unique features reflecting robust helper function, lack of terminal differentiation, and high proliferative potential. bioRxiv. 2020 Aug 03.
Neidleman J, Luo X, Frouard J, Xie G, Gill G, Stein ES, McGregor M, Ma T, George A, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR. PMID: 32577663; PMCID: PMC7302219.
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HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread. Elife. 2020 05 26; 9.
Ma T, Luo X, George AF, Mukherjee G, Sen N, Spitzer TL, Giudice LC, Greene WC, Roan NR. PMID: 32452381; PMCID: PMC7250576.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection. PLoS Pathog. 2020 04; 16(4):e1008450.
Hsiao F, Frouard J, Gramatica A, Xie G, Telwatte S, Lee GQ, Roychoudhury P, Schwarzer R, Luo X, Yukl SA, Lee S, Hoh R, Deeks SG, Jones RB, Cavrois M, Greene WC, Roan NR. PMID: 32353080; PMCID: PMC7192375.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling. Hum Reprod. 2020 03 27; 35(3):617-640.
George AF, Jang KS, Nyegaard M, Neidleman J, Spitzer TL, Xie G, Chen JC, Herzig E, Laustsen A, Marques de Menezes EG, Houshdaran S, Pilcher CD, Norris PJ, Jakobsen MR, Greene WC, Giudice LC, Roan NR. PMID: 32219408; PMCID: PMC7105328.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Reduce and Control: A Combinatorial Strategy for Achieving Sustained HIV Remissions in the Absence of Antiretroviral Therapy. Viruses. 2020 02 08; 12(2).
Schwarzer R, Gramatica A, Greene WC. PMID: 32046251; PMCID: PMC7077203.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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HIV-2 Depletes CD4 T Cells through Pyroptosis despite Vpx-Dependent Degradation of SAMHD1. J Virol. 2019 12 15; 93(24).
Luo X, Herzig E, Doitsh G, Grimmett ZW, Muñoz-Arias I, Greene WC. PMID: 31578293; PMCID: PMC6880156.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency. Retrovirology. 2019 11 11; 16(1):32.
Telwatte S, Morón-López S, Aran D, Kim P, Hsieh C, Joshi S, Montano M, Greene WC, Butte AJ, Wong JK, Yukl SA. PMID: 31711503; PMCID: PMC6849327.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform. Cell. 2019 10 31; 179(4):880-894.e10.
Herzig E, Kim KC, Packard TA, Vardi N, Schwarzer R, Gramatica A, Deeks SG, Williams SR, Landgraf K, Killeen N, Martin DW, Weinberger LS, Greene WC. PMID: 31668804; PMCID: PMC6922308.
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PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
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Tissue microenvironment initiates an immune response to structural components of Staphylococcus aureus. Exp Dermatol. 2019 02; 28(2):161-168.
Mainzer C, Packard T, Bordes S, Closs B, Greene WC, Elias PM, Uchida Y. PMID: 30566255; PMCID: PMC6706075.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Distinct mechanisms regulate IL1B gene transcription in lymphoid CD4 T cells and monocytes. Cytokine. 2018 11; 111:373-381.
Pulugulla SH, Packard TA, Galloway NLK, Grimmett ZW, Doitsh G, Adamik J, Galson DL, Greene WC, Auron PE. PMID: 30300855; PMCID: PMC6364691.
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PubMed Mentions:
17 Translation:
HumansCells
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Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma. Biol Reprod. 2018 08 01; 99(2):336-348.
Martin JW, Chen JC, Neidleman J, Tatsumi K, Hu J, Giudice LC, Greene WC, Roan NR. PMID: 29518187; PMCID: PMC6084595.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4+ T cells. Elife. 2018 05 01; 7.
Battivelli E, Dahabieh MS, Abdel-Mohsen M, Svensson JP, Tojal Da Silva I, Cohn LB, Gramatica A, Deeks S, Greene WC, Pillai SK, Verdin E. PMID: 29714165; PMCID: PMC5973828.
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PubMed Mentions:
94 Fields:
Translation:
HumansCells
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Mass Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells. Cell Rep. 2017 07 25; 20(4):984-998.
Cavrois M, Banerjee T, Mukherjee G, Raman N, Hussien R, Rodriguez BA, Vasquez J, Spitzer MH, Lazarus NH, Jones JJ, Ochsenbauer C, McCune JM, Butcher EC, Arvin AM, Sen N, Greene WC, Roan NR. PMID: 28746881; PMCID: PMC5560086.
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PubMed Mentions:
47 Fields:
Translation:
HumansCells
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Semen amyloids participate in spermatozoa selection and clearance. Elife. 2017 06 27; 6.
Roan NR, Sandi-Monroy N, Kohgadai N, Usmani SM, Hamil KG, Neidleman J, Montano M, Ständker L, Röcker A, Cavrois M, Rosen J, Marson K, Smith JF, Pilcher CD, Gagsteiger F, Sakk O, O'Rand M, Lishko PV, Kirchhoff F, Münch J, Greene WC. PMID: 28653619; PMCID: PMC5487211.
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PubMed Mentions:
39 Fields:
Translation:
HumansCells
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SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency. Cell Host Microbe. 2017 May 10; 21(5):569-579.e6.
Boehm D, Jeng M, Camus G, Gramatica A, Schwarzer R, Johnson JR, Hull PA, Montano M, Sakane N, Pagans S, Godin R, Deeks SG, Krogan NJ, Greene WC, Ott M. PMID: 28494238; PMCID: PMC5490666.
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PubMed Mentions:
54 Fields:
Translation:
HumansCells
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Corrigendum: Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection. Nature. 2017 04 06; 544(7648):124.
Doitsh G, Galloway NL, Geng X, Yang Z, Monroe KM, Zepeda O, Hunt PW, Hatano H, Sowinski S, Muñoz-Arias I, Greene WC. PMID: 28329768.
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PubMed Mentions:
11 Fields:
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Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells. PLoS Pathog. 2017 02; 13(2):e1006163.
Neidleman JA, Chen JC, Kohgadai N, Müller JA, Laustsen A, Thavachelvam K, Jang KS, Stürzel CM, Jones JJ, Ochsenbauer C, Chitre A, Somsouk M, Garcia MM, Smith JF, Greenblatt RM, Münch J, Jakobsen MR, Giudice LC, Greene WC, Roan NR. PMID: 28207890; PMCID: PMC5312882.
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PubMed Mentions:
39 Fields:
Translation:
HumansCells
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The mTOR Complex Controls HIV Latency. Cell Host Microbe. 2016 Dec 14; 20(6):785-797.
Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, Krogan NJ, Siliciano RF, Weissman JS, Verdin E. PMID: 27978436; PMCID: PMC5354304.
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PubMed Mentions:
119 Fields:
Translation:
HumansCells
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Stimulating the RIG-I pathway to kill cells in the latent HIV reservoir following viral reactivation. Nat Med. 2016 07; 22(7):807-11.
Li P, Kaiser P, Lampiris HW, Kim P, Yukl SA, Havlir DV, Greene WC, Wong JK. PMID: 27294875; PMCID: PMC5004598.
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PubMed Mentions:
66 Fields:
Translation:
HumansCells
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Gallic Acid Is an Antagonist of Semen Amyloid Fibrils That Enhance HIV-1 Infection. J Biol Chem. 2016 Jul 01; 291(27):14045-14055.
LoRicco JG, Xu CS, Neidleman J, Bergkvist M, Greene WC, Roan NR, Makhatadze GI. PMID: 27226574; PMCID: PMC4933164.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Dissecting How CD4 T Cells Are Lost During HIV Infection. Cell Host Microbe. 2016 Mar 09; 19(3):280-91.
Doitsh G, Greene WC. PMID: 26962940; PMCID: PMC4835240.
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PubMed Mentions:
110 Fields:
Translation:
HumansCells
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Blood-Derived CD4 T Cells Naturally Resist Pyroptosis during Abortive HIV-1 Infection. Cell Host Microbe. 2015 Oct 14; 18(4):463-70.
Muñoz-Arias I, Doitsh G, Yang Z, Sowinski S, Ruelas D, Greene WC. PMID: 26468749; PMCID: PMC4627664.
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PubMed Mentions:
51 Fields:
Translation:
HumansCells
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Cell-to-Cell Transmission of HIV-1 Is Required to Trigger Pyroptotic Death of Lymphoid-Tissue-Derived CD4 T Cells. Cell Rep. 2015 Sep 08; 12(10):1555-1563.
Galloway NL, Doitsh G, Monroe KM, Yang Z, Muñoz-Arias I, Levy DN, Greene WC. PMID: 26321639; PMCID: PMC4565731.
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PubMed Mentions:
78 Fields:
Translation:
HumansCells
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MicroRNA-155 Reinforces HIV Latency. J Biol Chem. 2015 May 29; 290(22):13736-48.
Ruelas DS, Chan JK, Oh E, Heidersbach AJ, Hebbeler AM, Chavez L, Verdin E, Rape M, Greene WC. PMID: 25873391; PMCID: PMC4447952.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Semen enhances HIV infectivity and impairs the antiviral efficacy of microbicides. Sci Transl Med. 2014 Nov 12; 6(262):262ra157.
Zirafi O, Kim KA, Roan NR, Kluge SF, Müller JA, Jiang S, Mayer B, Greene WC, Kirchhoff F, Münch J. PMID: 25391483; PMCID: PMC4372245.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansCells
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HIV-1 Fusion Assay. Bio Protoc. 2014 Aug 20; 4(16).
Cavrois M, Neidleman J, Greene WC. PMID: 27525294; PMCID: PMC4982656.
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PubMed Mentions:
12
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A new activity for SAMHD1 in HIV restriction. Nat Med. 2014 Aug; 20(8):808-9.
Yang Z, Greene WC. PMID: 25100520.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Liquefaction of semen generates and later degrades a conserved semenogelin peptide that enhances HIV infection. J Virol. 2014 Jul; 88(13):7221-34.
Roan NR, Liu H, Usmani SM, Neidleman J, Müller JA, Avila-Herrera A, Gawanbacht A, Zirafi O, Chu S, Dong M, Kumar ST, Smith JF, Pollard KS, Fändrich M, Kirchhoff F, Münch J, Witkowska HE, Greene WC. PMID: 24741080; PMCID: PMC4054457.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansCells
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Interaction of fibronectin with semen amyloids synergistically enhances HIV infection. J Infect Dis. 2014 Oct 01; 210(7):1062-6.
Roan NR, Chu S, Liu H, Neidleman J, Witkowska HE, Greene WC. PMID: 24719472; PMCID: PMC4168303.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen. Nat Commun. 2014 Apr 01; 5:3508.
Usmani SM, Zirafi O, Müller JA, Sandi-Monroy NL, Yadav JK, Meier C, Weil T, Roan NR, Greene WC, Walther P, Nilsson KP, Hammarström P, Wetzel R, Pilcher CD, Gagsteiger F, Fändrich M, Kirchhoff F, Münch J. PMID: 24691351; PMCID: PMC4129123.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansCells
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Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts. Hum Reprod. 2014 Jun; 29(6):1255-70.
Chen JC, Johnson BA, Erikson DW, Piltonen TT, Barragan F, Chu S, Kohgadai N, Irwin JC, Greene WC, Giudice LC, Roan NR. PMID: 24626806; PMCID: PMC4017943.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansCells
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Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection. Nature. 2014 Jan 23; 505(7484):509-14.
Doitsh G, Galloway NL, Geng X, Yang Z, Monroe KM, Zepeda O, Hunt PW, Hatano H, Sowinski S, Muñoz-Arias I, Greene WC. PMID: 24356306; PMCID: PMC4047036.
View in:
PubMed Mentions:
575 Fields:
Translation:
HumansCells
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An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients. PLoS Pathog. 2013; 9(12):e1003834.
Spina CA, Anderson J, Archin NM, Bosque A, Chan J, Famiglietti M, Greene WC, Kashuba A, Lewin SR, Margolis DM, Mau M, Ruelas D, Saleh S, Shirakawa K, Siliciano RF, Singhania A, Soto PC, Terry VH, Verdin E, Woelk C, Wooden S, Xing S, Planelles V. PMID: 24385908; PMCID: PMC3873446.
View in:
PubMed Mentions:
270 Fields:
Translation:
HumansCells
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IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV. Science. 2014 Jan 24; 343(6169):428-32.
Monroe KM, Yang Z, Johnson JR, Geng X, Doitsh G, Krogan NJ, Greene WC. PMID: 24356113; PMCID: PMC3976200.
View in:
PubMed Mentions:
279 Fields:
Translation:
HumansCells
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Enhanced fusion and virion incorporation for HIV-1 subtype C envelope glycoproteins with compact V1/V2 domains. J Virol. 2014 Feb; 88(4):2083-94.
Cavrois M, Neidleman J, Santiago ML, Derdeyn CA, Hunter E, Greene WC. PMID: 24335304; PMCID: PMC3911571.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Solutions to global health challenges: no more Band-Aids. J Clin Invest. 2013 Nov; 123(11):4967-70.
Greene WC. PMID: 24177468; PMCID: PMC3809817.
View in:
PubMed Mentions: Fields:
Translation:
HumansPHPublic Health
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Calcium/calcineurin synergizes with prostratin to promote NF-κB dependent activation of latent HIV. PLoS One. 2013; 8(10):e77749.
Chan JK, Bhattacharyya D, Lassen KG, Ruelas D, Greene WC. PMID: 24204950; PMCID: PMC3813743.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansCells
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An integrated overview of HIV-1 latency. Cell. 2013 Oct 24; 155(3):519-29.
Ruelas DS, Greene WC. PMID: 24243012; PMCID: PMC4361081.
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PubMed Mentions:
184 Fields:
Translation:
HumansCells
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Evasion of superinfection exclusion and elimination of primary viral RNA by an adapted strain of hepatitis C virus. J Virol. 2013 Dec; 87(24):13354-69.
Webster B, Ott M, Greene WC. PMID: 24089557; PMCID: PMC3838274.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein. PLoS Pathog. 2013; 9(4):e1003302.
Vogt DA, Camus G, Herker E, Webster BR, Tsou CL, Greene WC, Yen TS, Ott M. PMID: 23593007; PMCID: PMC3623766.
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PubMed Mentions:
59 Fields:
Translation:
HumansCells
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Rapid intracellular competition between hepatitis C viral genomes as a result of mitosis. J Virol. 2013 Jan; 87(1):581-96.
Webster B, Wissing S, Herker E, Ott M, Greene WC. PMID: 23097449; PMCID: PMC3536371.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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[Role of semen-derived amyloid fibrils as facilitators of HIV infection]. Med Sci (Paris). 2012 Apr; 28(4):358-60.
Roan NR, Cavrois M, Greene WC. PMID: 22549858.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Dynamic roles for NF-κB in HTLV-I and HIV-1 retroviral pathogenesis. Immunol Rev. 2012 Mar; 246(1):286-310.
Chan JK, Greene WC. PMID: 22435562.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansAnimalsCells
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Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):3035-40.
Pillai SK, Abdel-Mohsen M, Guatelli J, Skasko M, Monto A, Fujimoto K, Yukl S, Greene WC, Kovari H, Rauch A, Fellay J, Battegay M, Hirschel B, Witteck A, Bernasconi E, Ledergerber B, Günthard HF, Wong JK, Swiss HIV Cohort Study. PMID: 22315404; PMCID: PMC3286922.
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PubMed Mentions:
84 Fields:
Translation:
HumansCells
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A flexible model of HIV-1 latency permitting evaluation of many primary CD4 T-cell reservoirs. PLoS One. 2012; 7(1):e30176.
Lassen KG, Hebbeler AM, Bhattacharyya D, Lobritz MA, Greene WC. PMID: 22291913; PMCID: PMC3265466.
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PubMed Mentions:
88 Fields:
Translation:
HumansCells
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Differential transmission of HIV traversing fetal oral/intestinal epithelia and adult oral epithelia. J Virol. 2012 Mar; 86(5):2556-70.
Tugizov SM, Herrera R, Veluppillai P, Greenspan D, Soros V, Greene WC, Levy JA, Palefsky JM. PMID: 22205732; PMCID: PMC3302289.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansCellsPHPublic Health
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Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection. Cell Host Microbe. 2011 Dec 15; 10(6):541-50.
Roan NR, Müller JA, Liu H, Chu S, Arnold F, Stürzel CM, Walther P, Dong M, Witkowska HE, Kirchhoff F, Münch J, Greene WC. PMID: 22177559; PMCID: PMC3257029.
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PubMed Mentions:
93 Fields:
Translation:
HumansCells
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Naturally occurring fragments from two distinct regions of the prostatic acid phosphatase form amyloidogenic enhancers of HIV infection. J Virol. 2012 Jan; 86(2):1244-9.
Arnold F, Schnell J, Zirafi O, Stürzel C, Meier C, Weil T, Ständker L, Forssmann WG, Roan NR, Greene WC, Kirchhoff F, Münch J. PMID: 22090109; PMCID: PMC3255800.
View in:
PubMed Mentions:
60 Fields:
Translation:
HumansCells
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Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility. Hum Mol Genet. 2012 Jan 01; 21(1):208-18.
Wissing S, Muñoz-Lopez M, Macia A, Yang Z, Montano M, Collins W, Garcia-Perez JL, Moran JV, Greene WC. PMID: 21989055; PMCID: PMC3235014.
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PubMed Mentions:
87 Fields:
Translation:
HumansCells
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Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response. PLoS Pathog. 2011 Oct; 7(10):e1002284.
Smith DS, Guo K, Barrett BS, Heilman KJ, Evans LH, Hasenkrug KJ, Greene WC, Santiago ML. PMID: 21998583; PMCID: PMC3188525.
View in:
PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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HIV latency. Cold Spring Harb Perspect Med. 2011 Sep; 1(1):a007096.
Siliciano RF, Greene WC. PMID: 22229121; PMCID: PMC3234450.
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PubMed Mentions:
313 Fields:
Translation:
HumansCells
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Endogenous APOBEC3B restricts LINE-1 retrotransposition in transformed cells and human embryonic stem cells. J Biol Chem. 2011 Oct 21; 286(42):36427-37.
Wissing S, Montano M, Garcia-Perez JL, Moran JV, Greene WC. PMID: 21878639; PMCID: PMC3196128.
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PubMed Mentions:
66 Fields:
Translation:
HumansCells
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Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1). PLoS Pathog. 2011 Aug; 7(8):e1002184.
Sakane N, Kwon HS, Pagans S, Kaehlcke K, Mizusawa Y, Kamada M, Lassen KG, Chan J, Greene WC, Schnoelzer M, Ott M. PMID: 21876670; PMCID: PMC3158049.
View in:
PubMed Mentions:
58 Fields:
Translation:
AnimalsCells
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NF-κB/Rel: agonist and antagonist roles in HIV-1 latency. Curr Opin HIV AIDS. 2011 Jan; 6(1):12-8.
Chan JK, Greene WC. PMID: 21242888; PMCID: PMC3493179.
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PubMed Mentions:
48 Fields:
Translation:
HumansCells
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Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue. Cell. 2010 Nov 24; 143(5):789-801.
Doitsh G, Cavrois M, Lassen KG, Zepeda O, Yang Z, Santiago ML, Hebbeler AM, Greene WC. PMID: 21111238; PMCID: PMC3026834.
View in:
PubMed Mentions:
240 Fields:
Translation:
HumansCells
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HIV is inactivated after transepithelial migration via adult oral epithelial cells but not fetal epithelial cells. Virology. 2011 Jan 20; 409(2):211-22.
Tugizov SM, Herrera R, Veluppillai P, Greenspan D, Soros V, Greene WC, Levy JA, Palefsky JM. PMID: 21056450; PMCID: PMC3034249.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansCells
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Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor. J Virol. 2011 Jan; 85(1):189-99.
Santiago ML, Smith DS, Barrett BS, Montano M, Benitez RL, Pelanda R, Hasenkrug KJ, Greene WC. PMID: 20980520; PMCID: PMC3014173.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Identification of two APOBEC3F splice variants displaying HIV-1 antiviral activity and contrasting sensitivity to Vif. J Biol Chem. 2010 Sep 17; 285(38):29326-35.
Lassen KG, Wissing S, Lobritz MA, Santiago M, Greene WC. PMID: 20624919; PMCID: PMC2937965.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI. Retrovirology. 2010 Jun 23; 7:55.
Kim KA, Yolamanova M, Zirafi O, Roan NR, Staendker L, Forssmann WG, Burgener A, Dejucq-Rainsford N, Hahn BH, Shaw GM, Greene WC, Kirchhoff F, Münch J. PMID: 20573198; PMCID: PMC2914040.
View in:
PubMed Mentions:
81 Fields:
Translation:
HumansAnimalsCells
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Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo. J Immunol. 2010 Jul 15; 185(2):1114-23.
Santiago ML, Benitez RL, Montano M, Hasenkrug KJ, Greene WC. PMID: 20566830; PMCID: PMC3024598.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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HIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factors. Mol Aspects Med. 2010 Oct; 31(5):383-97.
Wissing S, Galloway NL, Greene WC. PMID: 20538015; PMCID: PMC2967609.
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PubMed Mentions:
36 Fields:
Translation:
HumansCells
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Measuring HIV fusion mediated by envelopes from primary viral isolates. Methods. 2011 Jan; 53(1):34-8.
Cavrois M, Neidleman J, Galloway N, Derdeyn CA, Hunter E, Greene WC. PMID: 20554044; PMCID: PMC3563671.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection). J Biol Chem. 2010 Jan 15; 285(3):1861-9.
Roan NR, Sowinski S, Münch J, Kirchhoff F, Greene WC. PMID: 19897482; PMCID: PMC2804344.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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APOBEC3G: an intracellular centurion. Philos Trans R Soc Lond B Biol Sci. 2009 Mar 12; 364(1517):689-703.
Chiu YL, Greene WC. PMID: 19008196; PMCID: PMC2660915.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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The challenge of finding a cure for HIV infection. Science. 2009 Mar 06; 323(5919):1304-7.
Richman DD, Margolis DM, Delaney M, Greene WC, Hazuda D, Pomerantz RJ. PMID: 19265012.
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PubMed Mentions:
458 Fields:
Translation:
HumansAnimalsCells
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Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo. Retrovirology. 2009 Jan 13; 6:2.
Michel N, Goffinet C, Ganter K, Allespach I, Kewalramani VN, Saifuddin M, Littman DR, Greene WC, Goldsmith MA, Keppler OT. PMID: 19144136; PMCID: PMC2631513.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Unsung hero Robert C. Gallo. Science. 2009 Jan 09; 323(5911):206-7.
Abbadessa G, Accolla R, Aiuti F, Albini A, Aldovini A, Alfano M, Antonelli G, Bartholomew C, Bentwich Z, Bertazzoni U, Berzofsky JA, Biberfeld P, Boeri E, Buonaguro L, Buonaguro FM, Bukrinsky M, Burny A, Caruso A, Cassol S, Chandra P, Ceccherini-Nelli L, Chieco-Bianchi L, Clerici M, Colombini-Hatch S, de Giuli Morghen C, de Maria A, de Rossi A, Dierich M, Della-Favera R, Dolei A, Douek D, Erfle V, Felber B, Fiorentini S, Franchini G, Gershoni JM, Gotch F, Green P, Greene WC, Hall W, Haseltine W, Jacobson S, Kallings LO, Kalyanaraman VS, Katinger H, Khalili K, Klein G, Klein E, Klotman M, Klotman P, Kotler M, Kurth R, Lafeuillade A, La Placa M, Lewis J, Lillo F, Lisziewicz J, Lomonico A, Lopalco L, Lori F, Lusso P, Macchi B, Malim M, Margolis L, Markham PD, McClure M, Miller N, Mingari MC, Moretta L, Noonan D, O'Brien S, Okamoto T, Pal R, Palese P, Panet A, Pantaleo G, Pavlakis G, Pistello M, Plotkin S, Poli G, Pomerantz R, Radaelli A, Robertguroff M, Roederer M, Sarngadharan MG, Schols D, Secchiero P, Shearer G, Siccardi A, Stevenson M, Svoboda J, Tartaglia J, Torelli G, Tornesello ML, Tschachler E, Vaccarezza M, Vallbracht A, van Lunzen J, Varnier O, Vicenzi E, von Melchner H, Witz I, Zagury D, Zagury JF, Zauli G, Zipeto D. PMID: 19131607.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Guidelines for naming nonprimate APOBEC3 genes and proteins. J Virol. 2009 Jan; 83(2):494-7.
LaRue RS, Andrésdóttir V, Blanchard Y, Conticello SG, Derse D, Emerman M, Greene WC, Jónsson SR, Landau NR, Löchelt M, Malik HS, Malim MH, Münk C, O'Brien SJ, Pathak VK, Strebel K, Wain-Hobson S, Yu XF, Yuhki N, Harris RS. PMID: 18987154; PMCID: PMC2612408.
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PubMed Mentions:
150 Fields:
Translation:
Animals
-
The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection. J Virol. 2009 Jan; 83(1):73-80.
Roan NR, Münch J, Arhel N, Mothes W, Neidleman J, Kobayashi A, Smith-McCune K, Kirchhoff F, Greene WC. PMID: 18945786; PMCID: PMC2612336.
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PubMed Mentions:
105 Fields:
Translation:
HumansCells
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Novel targets for HIV therapy. Antiviral Res. 2008 Dec; 80(3):251-65.
Greene WC, Debyser Z, Ikeda Y, Freed EO, Stephens E, Yonemoto W, Buckheit RW, Esté JA, Cihlar T. PMID: 18789977.
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PubMed Mentions:
40 Fields:
Translation:
HumansAnimalsCells
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Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection. Science. 2008 Sep 05; 321(5894):1343-6.
Santiago ML, Montano M, Benitez R, Messer RJ, Yonemoto W, Chesebro B, Hasenkrug KJ, Greene WC. PMID: 18772436; PMCID: PMC2701658.
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PubMed Mentions:
95 Fields:
Translation:
AnimalsCells
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HIV vaccine research: the way forward. Science. 2008 Jul 25; 321(5888):530-2.
Fauci AS, Johnston MI, Dieffenbach CW, Burton DR, Hammer SM, Hoxie JA, Martin M, Overbaugh J, Watkins DI, Mahmoud A, Greene WC. PMID: 18653883.
View in:
PubMed Mentions:
119 Fields:
Translation:
HumansAnimalsCells
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The achilles heel of the trojan horse model of HIV-1 trans-infection. PLoS Pathog. 2008 Jun 27; 4(6):e1000051.
Cavrois M, Neidleman J, Greene WC. PMID: 18584030; PMCID: PMC2430767.
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PubMed Mentions:
37 Fields:
Translation:
HumansCells
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Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation. Cell Host Microbe. 2008 Mar 13; 3(3):158-67.
Kwon HS, Brent MM, Getachew R, Jayakumar P, Chen LF, Schnolzer M, McBurney MW, Marmorstein R, Greene WC, Ott M. PMID: 18329615; PMCID: PMC2680745.
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PubMed Mentions:
90 Fields:
Translation:
HumansAnimalsCells
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The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements. Annu Rev Immunol. 2008; 26:317-53.
Chiu YL, Greene WC. PMID: 18304004.
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PubMed Mentions:
260 Fields:
Translation:
HumansAnimalsCells
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A seminal finding for understanding HIV transmission. Cell. 2007 Dec 14; 131(6):1044-6.
Roan NR, Greene WC. PMID: 18083095.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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A history of AIDS: looking back to see ahead. Eur J Immunol. 2007 Nov; 37 Suppl 1:S94-102.
Greene WC. PMID: 17972351.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Primary T-cells from human CD4/CCR5-transgenic rats support all early steps of HIV-1 replication including integration, but display impaired viral gene expression. Retrovirology. 2007 Jul 26; 4:53.
Goffinet C, Michel N, Allespach I, Tervo HM, Hermann V, Kräusslich HG, Greene WC, Keppler OT. PMID: 17655755; PMCID: PMC1971067.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Regulation of HIV-1 latency by T-cell activation. Cytokine. 2007 Jul; 39(1):63-74.
Williams SA, Greene WC. PMID: 17643313; PMCID: PMC2063506.
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PubMed Mentions:
61 Translation:
HumansCells
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The CD16+ monocyte subset is more permissive to infection and preferentially harbors HIV-1 in vivo. J Immunol. 2007 May 15; 178(10):6581-9.
Ellery PJ, Tippett E, Chiu YL, Paukovics G, Cameron PU, Solomon A, Lewin SR, Gorry PR, Jaworowski A, Greene WC, Sonza S, Crowe SM. PMID: 17475889.
View in:
PubMed Mentions:
207 Fields:
Translation:
HumansCells
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Sustained induction of NF-kappa B is required for efficient expression of latent human immunodeficiency virus type 1. J Virol. 2007 Jun; 81(11):6043-56.
Williams SA, Kwon H, Chen LF, Greene WC. PMID: 17376917; PMCID: PMC1900291.
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PubMed Mentions:
89 Fields:
Translation:
HumansCells
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APOBEC3G and HIV-1: strike and counterstrike. Curr HIV/AIDS Rep. 2007 Feb; 4(1):3-9.
Soros VB, Greene WC. PMID: 17338854.
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PubMed Mentions:
2 Fields:
-
Newly synthesized APOBEC3G is incorporated into HIV virions, inhibited by HIV RNA, and subsequently activated by RNase H. PLoS Pathog. 2007 Feb; 3(2):e15.
Soros VB, Yonemoto W, Greene WC. PMID: 17291161; PMCID: PMC1796622.
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PubMed Mentions:
89 Fields:
Translation:
HumansCells
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In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 virions. PLoS Pathog. 2007 Jan; 3(1):e4.
Cavrois M, Neidleman J, Kreisberg JF, Greene WC. PMID: 17238285; PMCID: PMC1779297.
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Distinct patterns of cytokine regulation of APOBEC3G expression and activity in primary lymphocytes, macrophages, and dendritic cells. J Biol Chem. 2007 Feb 09; 282(6):3539-46.
Stopak KS, Chiu YL, Kropp J, Grant RM, Greene WC. PMID: 17110377.
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PubMed Mentions:
94 Fields:
Translation:
HumansCells
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A plea for justice for jailed medical workers. Science. 2006 Nov 10; 314(5801):924-5.
Ahuja SK, Aiuti F, Berkhout B, Biberfeld P, Burton DR, Colizzi V, Deeks SG, Desrosiers RC, Dierich MP, Doms RW, Emerman M, Gallo RC, Girard M, Greene WC, Hoxie JA, Hunter E, Klein G, Korber B, Kuritzkes DR, Lederman MM, Malim MH, Marx PA, McCune JM, McMichael A, Miller C, Miller V, Montagnier L, Montefiori DC, Moore JP, Nixon DF, Overbaugh J, Pauza CD, Richman DD, Saag MS, Sattentau Q, Schooley RT, Shattock R, Shaw GM, Stevenson M, Trkola A, Wainberg MA, Weiss RA, Wolinsky S, Zack JA. PMID: 17062652.
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PubMed Mentions: Fields:
Translation:
HumansCellsPHPublic Health
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High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition. Proc Natl Acad Sci U S A. 2006 Oct 17; 103(42):15588-93.
Chiu YL, Witkowska HE, Hall SC, Santiago M, Soros VB, Esnault C, Heidmann T, Greene WC. PMID: 17030807; PMCID: PMC1592537.
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PubMed Mentions:
150 Fields:
Translation:
HumansCells
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NF-kappaB/Rel regulates inhibitory and excitatory neuronal function and synaptic plasticity. Mol Cell Biol. 2006 Oct; 26(19):7283-98.
O'Mahony A, Raber J, Montano M, Foehr E, Han V, Lu SM, Kwon H, LeFevour A, Chakraborty-Sett S, Greene WC. PMID: 16980629; PMCID: PMC1592877.
View in:
PubMed Mentions:
59 Fields:
Translation:
AnimalsCells
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Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo. J Virol. 2006 Nov; 80(21):10407-18.
Zimmerman ES, Sherman MP, Blackett JL, Neidleman JA, Kreis C, Mundt P, Williams SA, Warmerdam M, Kahn J, Hecht FM, Grant RM, de Noronha CM, Weyrich AS, Greene WC, Planelles V. PMID: 16956949; PMCID: PMC1641771.
View in:
PubMed Mentions:
70 Fields:
Translation:
HumansCells
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APOBEC3G and HIV-1: strike and counterstrike. Curr Infect Dis Rep. 2006 Jun; 8(4):317-23.
Soros VB, Greene WC. PMID: 16822376.
View in:
PubMed Mentions:
3
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Multifaceted antiviral actions of APOBEC3 cytidine deaminases. Trends Immunol. 2006 Jun; 27(6):291-7.
Chiu YL, Greene WC. PMID: 16678488.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Endogenous factors enhance HIV infection of tissue naive CD4 T cells by stimulating high molecular mass APOBEC3G complex formation. J Exp Med. 2006 Apr 17; 203(4):865-70.
Kreisberg JF, Yonemoto W, Greene WC. PMID: 16606671; PMCID: PMC2118295.
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PubMed Mentions:
73 Fields:
Translation:
HumansCells
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Interleukin-18-induced human coronary artery smooth muscle cell migration is dependent on NF-kappaB- and AP-1-mediated matrix metalloproteinase-9 expression and is inhibited by atorvastatin. J Biol Chem. 2006 Jun 02; 281(22):15099-109.
Chandrasekar B, Mummidi S, Mahimainathan L, Patel DN, Bailey SR, Imam SZ, Greene WC, Valente AJ. PMID: 16554298.
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PubMed Mentions:
80 Fields:
Translation:
HumansCells
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Human immunodeficiency virus fusion to dendritic cells declines as cells mature. J Virol. 2006 Feb; 80(4):1992-9.
Cavrois M, Neidleman J, Kreisberg JF, Fenard D, Callebaut C, Greene WC. PMID: 16439555; PMCID: PMC1367165.
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PubMed Mentions:
39 Fields:
Translation:
HumansCells
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APOBEC3 cytidine deaminases: distinct antiviral actions along the retroviral life cycle. J Biol Chem. 2006 Mar 31; 281(13):8309-12.
Chiu YL, Greene WC. PMID: 16407183.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
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NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. EMBO J. 2006 Jan 11; 25(1):139-49.
Williams SA, Chen LF, Kwon H, Ruiz-Jarabo CM, Verdin E, Greene WC. PMID: 16319923; PMCID: PMC1356344.
View in:
PubMed Mentions:
271 Fields:
Translation:
HumansCells
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Nef is physically recruited into the immunological synapse and potentiates T cell activation early after TCR engagement. J Immunol. 2005 Nov 01; 175(9):6050-7.
Fenard D, Yonemoto W, de Noronha C, Cavrois M, Williams SA, Greene WC. PMID: 16237100.
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PubMed Mentions:
59 Fields:
Translation:
HumansCells
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NF-kappaB RelA phosphorylation regulates RelA acetylation. Mol Cell Biol. 2005 Sep; 25(18):7966-75.
Chen LF, Williams SA, Mu Y, Nakano H, Duerr JM, Buckbinder L, Greene WC. PMID: 16135789; PMCID: PMC1234328.
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PubMed Mentions:
226 Fields:
Translation:
HumansAnimalsCells
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Lethal cutaneous disease in transgenic mice conditionally expressing type I human T cell leukemia virus Tax. J Biol Chem. 2005 Oct 21; 280(42):35713-22.
Kwon H, Ogle L, Benitez B, Bohuslav J, Montano M, Felsher DW, Greene WC. PMID: 16105841.
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PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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Assessing acetylation of NF-kappaB. Methods. 2005 Aug; 36(4):368-75.
Chen LF, Greene WC. PMID: 16111893.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Host factors regulating post-integration latency of HIV. Trends Microbiol. 2005 Apr; 13(4):137-9.
Williams SA, Greene WC. PMID: 15817380.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Rodent cells support key functions of the human immunodeficiency virus type 1 pathogenicity factor Nef. J Virol. 2005 Feb; 79(3):1655-65.
Keppler OT, Allespach I, Schüller L, Fenard D, Greene WC, Fackler OT. PMID: 15650191; PMCID: PMC544094.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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Protecting APOBEC3G: a potential new target for HIV drug discovery. Curr Opin Investig Drugs. 2005 Feb; 6(2):141-7.
Stopak K, Greene WC. PMID: 15751736.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Studies of ebola virus glycoprotein-mediated entry and fusion by using pseudotyped human immunodeficiency virus type 1 virions: involvement of cytoskeletal proteins and enhancement by tumor necrosis factor alpha. J Virol. 2005 Jan; 79(2):918-26.
Yonezawa A, Cavrois M, Greene WC. PMID: 15613320; PMCID: PMC538559.
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PubMed Mentions:
95 Fields:
Translation:
HumansCells
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HIV-1 virion fusion assay: uncoating not required and no effect of Nef on fusion. Virology. 2004 Oct 10; 328(1):36-44.
Cavrois M, Neidleman J, Yonemoto W, Fenard D, Greene WC. PMID: 15380356.
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PubMed Mentions:
41 Fields:
Translation:
HumansCells
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The brightening future of HIV therapeutics. Nat Immunol. 2004 Sep; 5(9):867-71.
Greene WC. PMID: 15334078.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Redistricting the retroviral restriction factors. Nat Med. 2004 Aug; 10(8):778-80.
Greene WC. PMID: 15286773.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Prostratin antagonizes HIV latency by activating NF-kappaB. J Biol Chem. 2004 Oct 01; 279(40):42008-17.
Williams SA, Chen LF, Kwon H, Fenard D, Bisgrove D, Verdin E, Greene WC. PMID: 15284245.
View in:
PubMed Mentions:
182 Fields:
Translation:
HumansCells
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Shaping the nuclear action of NF-kappaB. Nat Rev Mol Cell Biol. 2004 May; 5(5):392-401.
Chen LF, Greene WC. PMID: 15122352.
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PubMed Mentions:
500 Fields:
Translation:
HumansAnimalsCells
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p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1. J Biol Chem. 2004 Jun 18; 279(25):26115-25.
Bohuslav J, Chen LF, Kwon H, Mu Y, Greene WC. PMID: 15073170.
View in:
PubMed Mentions:
98 Fields:
Translation:
HumansAnimalsCells
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Human T-cell lymphotropic virus type 1 tax induction of biologically Active NF-kappaB requires IkappaB kinase-1-mediated phosphorylation of RelA/p65. J Biol Chem. 2004 Apr 30; 279(18):18137-45.
O'Mahony AM, Montano M, Van Beneden K, Chen LF, Greene WC. PMID: 14963024.
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PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
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Compensatory link between fusion and endocytosis of human immunodeficiency virus type 1 in human CD4 T lymphocytes. J Virol. 2004 Feb; 78(3):1375-83.
Schaeffer E, Soros VB, Greene WC. PMID: 14722292; PMCID: PMC321368.
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PubMed Mentions:
69 Fields:
Translation:
HumansCells
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How resting T cells deMURR HIV infection. Nat Immunol. 2004 Jan; 5(1):18-9.
Greene WC. PMID: 14699403.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Regulation of NF-kappaB action by reversible acetylation. Novartis Found Symp. 2004; 259:208-17; discussion 218-25.
Greene WC, Chen LF. PMID: 15171256.
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PubMed Mentions:
46 Fields:
Translation:
HumansCells
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Fluorescence resonance energy transfer-based HIV-1 virion fusion assay. Methods Mol Biol. 2004; 263:333-44.
Cavrois M, Neidleman J, Bigos M, Greene WC. PMID: 14976375.
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PubMed Mentions:
30 Fields:
Translation:
Cells
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HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability. Mol Cell. 2003 Sep; 12(3):591-601.
Stopak K, de Noronha C, Yonemoto W, Greene WC. PMID: 14527406.
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PubMed Mentions:
389 Fields:
Translation:
HumansCells
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Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation. J Mol Med (Berl). 2003 Sep; 81(9):549-57.
Chen LF, Greene WC. PMID: 12920522.
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PubMed Mentions:
94 Fields:
Translation:
HumansAnimalsCells
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Cyclophilin A interacts with HIV-1 Vpr and is required for its functional expression. J Biol Chem. 2003 Oct 31; 278(44):43202-13.
Zander K, Sherman MP, Tessmer U, Bruns K, Wray V, Prechtel AT, Schubert E, Henklein P, Luban J, Neidleman J, Greene WC, Schubert U. PMID: 12881522.
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PubMed Mentions:
32 Fields:
Translation:
HumansCells
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Nuclear export of Vpr is required for efficient replication of human immunodeficiency virus type 1 in tissue macrophages. J Virol. 2003 Jul; 77(13):7582-9.
Sherman MP, de Noronha CM, Eckstein LA, Hataye J, Mundt P, Williams SA, Neidleman JA, Goldsmith MA, Greene WC. PMID: 12805458; PMCID: PMC164827.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis. J Virol. 2003 Feb; 77(3):2124-33.
Stoddart CA, Geleziunas R, Ferrell S, Linquist-Stepps V, Moreno ME, Bare C, Xu W, Yonemoto W, Bresnahan PA, McCune JM, Greene WC. PMID: 12525647; PMCID: PMC140869.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
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Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB. EMBO J. 2002 Dec 02; 21(23):6539-48.
Chen LF, Mu Y, Greene WC. PMID: 12456660; PMCID: PMC136963.
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PubMed Mentions:
373 Fields:
Translation:
Cells
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HIV-1 Vpr displays natural protein-transducing properties: implications for viral pathogenesis. Virology. 2002 Oct 10; 302(1):95-105.
Sherman MP, Schubert U, Williams SA, de Noronha CM, Kreisberg JF, Henklein P, Greene WC. PMID: 12429519.
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PubMed Mentions:
37 Fields:
Translation:
HumansCells
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A sensitive and specific enzyme-based assay detecting HIV-1 virion fusion in primary T lymphocytes. Nat Biotechnol. 2002 Nov; 20(11):1151-4.
Cavrois M, De Noronha C, Greene WC. PMID: 12355096.
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PubMed Mentions:
326 Fields:
Translation:
HumansCells
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Insights into the biology of HIV-1 viral protein R. DNA Cell Biol. 2002 Sep; 21(9):679-88.
Sherman MP, De Noronha CM, Williams SA, Greene WC. PMID: 12396611.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy. Nat Med. 2002 Jul; 8(7):673-80.
Greene WC, Peterlin BM. PMID: 12091904.
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PubMed Mentions:
88 Fields:
Translation:
HumansCells
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Slipping through the door: HIV entry into the nucleus. Microbes Infect. 2002 Jan; 4(1):67-73.
Sherman MP, Greene WC. PMID: 11825777.
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PubMed Mentions:
41 Fields:
Translation:
HumansCells
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HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells. J Exp Med. 2001 Nov 19; 194(10):1407-19.
Eckstein DA, Sherman MP, Penn ML, Chin PS, De Noronha CM, Greene WC, Goldsmith MA. PMID: 11714748; PMCID: PMC2193684.
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PubMed Mentions:
58 Fields:
Translation:
HumansCells
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Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr. Science. 2001 Nov 02; 294(5544):1105-8.
de Noronha CM, Sherman MP, Lin HW, Cavrois MV, Moir RD, Goldman RD, Greene WC. PMID: 11691994.
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PubMed Mentions:
125 Fields:
Translation:
HumansCells
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Duration of nuclear NF-kappaB action regulated by reversible acetylation. Science. 2001 Aug 31; 293(5535):1653-7.
Fischle W, Verdin E, Greene WC. PMID: 11533489.
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PubMed Mentions:
488 Fields:
Translation:
HumansAnimalsCells
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HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Nature. 2001 Apr 12; 410(6830):834-8.
Geleziunas R, Xu W, Takeda K, Ichijo H, Greene WC. PMID: 11298454.
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PubMed Mentions:
113 Fields:
Translation:
HumansCells
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Human immunodeficiency virus type 1 Nef functions at the level of virus entry by enhancing cytoplasmic delivery of virions. J Virol. 2001 Mar; 75(6):2993-3000.
Schaeffer E, Geleziunas R, Greene WC. PMID: 11222724; PMCID: PMC115925.
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PubMed Mentions:
71 Fields:
Translation:
HumansCells
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Nucleocytoplasmic shuttling by human immunodeficiency virus type 1 Vpr. J Virol. 2001 Feb; 75(3):1522-32.
Sherman MP, de Noronha CM, Heusch MI, Greene S, Greene WC. PMID: 11152524; PMCID: PMC114057.
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PubMed Mentions:
39 Fields:
Translation:
HumansCells
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The NF-kappa B-inducing kinase induces PC12 cell differentiation and prevents apoptosis. J Biol Chem. 2000 Nov 03; 275(44):34021-4.
Foehr ED, Bohuslav J, Chen LF, DeNoronha C, Geleziunas R, Lin X, O'Mahony A, Greene WC. PMID: 10980190.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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NF-kappa B signaling promotes both cell survival and neurite process formation in nerve growth factor-stimulated PC12 cells. J Neurosci. 2000 Oct 15; 20(20):7556-63.
Foehr ED, Lin X, O'Mahony A, Geleziunas R, Bradshaw RA, Greene WC. PMID: 11027214; PMCID: PMC6772878.
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PubMed Mentions:
50 Fields:
Translation:
AnimalsCells
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Functional and structural characterization of synthetic HIV-1 Vpr that transduces cells, localizes to the nucleus, and induces G2 cell cycle arrest. J Biol Chem. 2000 Oct 13; 275(41):32016-26.
Henklein P, Bruns K, Sherman MP, Tessmer U, Licha K, Kopp J, de Noronha CM, Greene WC, Wray V, Schubert U. PMID: 10903315.
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PubMed Mentions:
43 Fields:
Translation:
HumansCells
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Cotranslational dimerization of the Rel homology domain of NF-kappaB1 generates p50-p105 heterodimers and is required for effective p50 production. EMBO J. 2000 Sep 01; 19(17):4712-22.
Lin L, DeMartino GN, Greene WC. PMID: 10970863; PMCID: PMC302078.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Human immunodeficiency virus type 1 Vpr contains two leucine-rich helices that mediate glucocorticoid receptor coactivation independently of its effects on G(2) cell cycle arrest. J Virol. 2000 Sep; 74(17):8159-65.
Sherman MP, de Noronha CM, Pearce D, Greene WC. PMID: 10933727; PMCID: PMC112350.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta. Mol Cell Biol. 2000 Apr; 20(8):2933-40.
Lin X, O'Mahony A, Mu Y, Geleziunas R, Greene WC. PMID: 10733597; PMCID: PMC85537.
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PubMed Mentions:
78 Fields:
Translation:
HumansCells
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Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions. Mol Cell Biol. 2000 Feb; 20(4):1170-8.
O'Mahony A, Lin X, Geleziunas R, Greene WC. PMID: 10648602; PMCID: PMC85235.
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PubMed Mentions:
38 Fields:
Translation:
HumansCells
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The generation of nfkb2 p52: mechanism and efficiency. Oncogene. 1999 Nov 04; 18(46):6201-8.
Heusch M, Lin L, Geleziunas R, Greene WC. PMID: 10597218.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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Cutting edge: SIV Nef protein utilizes both leucine- and tyrosine-based protein sorting pathways for down-regulation of CD4. J Immunol. 1999 Sep 15; 163(6):2977-81.
Bresnahan PA, Yonemoto W, Greene WC. PMID: 10477559.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kappaB acting through the NF-kappaB-inducing kinase and IkappaB kinases. Immunity. 1999 Feb; 10(2):271-80.
Lin X, Cunningham ET, Mu Y, Geleziunas R, Greene WC. PMID: 10072079.
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PubMed Mentions:
49 Fields:
Translation:
HumansCells
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Characterization of HIV-1 vpr nuclear import: analysis of signals and pathways. J Cell Biol. 1998 Nov 16; 143(4):875-85.
Jenkins Y, McEntee M, Weis K, Greene WC. PMID: 9817747; PMCID: PMC2132945.
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PubMed Mentions:
67 Fields:
Translation:
HumansCells
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A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor. Curr Biol. 1998 Nov 05; 8(22):1235-8.
Bresnahan PA, Yonemoto W, Ferrell S, Williams-Herman D, Geleziunas R, Greene WC. PMID: 9811606.
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PubMed Mentions:
113 Fields:
Translation:
HumansCells
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Molecular determinants of NF-kappaB-inducing kinase action. Mol Cell Biol. 1998 Oct; 18(10):5899-907.
Lin X, Mu Y, Cunningham ET, Marcu KB, Geleziunas R, Greene WC. PMID: 9742107; PMCID: PMC109176.
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PubMed Mentions:
39 Fields:
Translation:
HumansCells
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Diminished spontaneous apoptosis in lymphocytes from human immunodeficiency virus-infected long-term nonprogressors. J Infect Dis. 1998 Sep; 178(3):669-79.
Liegler TJ, Yonemoto W, Elbeik T, Vittinghoff E, Buchbinder SP, Greene WC. PMID: 9728534.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases. Mol Cell Biol. 1998 Sep; 18(9):5157-65.
Geleziunas R, Ferrell S, Lin X, Mu Y, Cunningham ET, Grant M, Connelly MA, Hambor JE, Marcu KB, Greene WC. PMID: 9710600; PMCID: PMC109101.
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PubMed Mentions:
79 Fields:
Translation:
HumansAnimalsCells
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Cotranslational biogenesis of NF-kappaB p50 by the 26S proteasome. Cell. 1998 Mar 20; 92(6):819-28.
Lin L, DeMartino GN, Greene WC. PMID: 9529257.
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PubMed Mentions:
79 Fields:
Translation:
AnimalsCells
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Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation. Curr Biol. 1997 Nov 01; 7(11):817-26.
Liu KD, Gaffen SL, Goldsmith MA, Greene WC. PMID: 9382798.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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The 90-kDa ribosomal S6 kinase (pp90rsk) phosphorylates the N-terminal regulatory domain of IkappaBalpha and stimulates its degradation in vitro. J Biol Chem. 1997 Aug 22; 272(34):21281-8.
Ghoda L, Lin X, Greene WC. PMID: 9261139.
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PubMed Mentions:
54 Fields:
Translation:
HumansAnimalsCells
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Intravirion generation of the C-terminal core domain of HIV-1 Nef by the HIV-1 protease is insufficient to enhance viral infectivity. Virology. 1997 Aug 04; 234(2):215-25.
Miller MD, Warmerdam MT, Ferrell SS, Benitez R, Greene WC. PMID: 9268152.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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HIV Rev-dependent binding of SF2/ASF to the Rev response element: possible role in Rev-mediated inhibition of HIV RNA splicing. Proc Natl Acad Sci U S A. 1997 Feb 04; 94(3):973-8.
Powell DM, Amaral MC, Wu JY, Maniatis T, Greene WC. PMID: 9023367; PMCID: PMC19624.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Interaction of the human T-lymphotropic virus type 1 Tax dimer with CREB and the viral 21-base-pair repeat. J Virol. 1996 Dec; 70(12):8368-74.
Tie F, Adya N, Greene WC, Giam CZ. PMID: 8970957; PMCID: PMC190925.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Unraveling the function of HIV type 1 Nef. AIDS Res Hum Retroviruses. 1996 Nov 20; 12(17):1579-82.
Geleziunas R, Miller MD, Greene WC. PMID: 8947291.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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c-rel regulation of IL-2 gene expression may be mediated through activation of AP-1. J Exp Med. 1996 Nov 01; 184(5):1663-9.
Shapiro VS, Mollenauer MN, Greene WC, Weiss A. PMID: 8920856; PMCID: PMC2192877.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity. J Biol Chem. 1996 Aug 30; 271(35):21381-90.
Gaffen SL, Lai SY, Ha M, Liu X, Hennighausen L, Greene WC, Goldsmith MA. PMID: 8702919.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Inhibition of HIV replication by sense and antisense rev response elements in HIV-based retroviral vectors. J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 01; 12(4):343-51.
Kim JH, McLinden RJ, Mosca JD, Vahey MT, Greene WC, Redfield RR. PMID: 8673542.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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The alpha chain of the IL-2 receptor determines the species specificity of high-affinity IL-2 binding. Cytokine. 1996 Aug; 8(8):613-21.
Liu KD, Greene WC, Goldsmith MA. PMID: 8894436.
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PubMed Mentions:
3 Translation:
HumansAnimalsCells
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Denying HIV safe haven. N Engl J Med. 1996 May 09; 334(19):1264-5.
Greene WC. PMID: 8606724.
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Translation:
HumansCells
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Human T lymphotropic virus-I infection of human T lymphocytes induces expression of the beta-galactoside-binding lectin, galectin-3. Am J Pathol. 1996 May; 148(5):1661-70.
Hsu DK, Hammes SR, Kuwabara I, Greene WC, Liu FT. PMID: 8623933; PMCID: PMC1861566.
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PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
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Is the Nef protein of HIV-1 required for pathogenesis? Trends Microbiol. 1996 May; 4(5):171-2; discussion 173.
Miller MD, Greene WC. PMID: 8727595.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation. Mol Cell Biol. 1996 Mar; 16(3):1058-65.
Sun S, Elwood J, Greene WC. PMID: 8622650; PMCID: PMC231088.
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PubMed Mentions:
59 Fields:
Translation:
HumansCells
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The molecular role of the common gamma c subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexes. Proc Natl Acad Sci U S A. 1996 Jan 09; 93(1):231-5.
Lai SY, Xu W, Gaffen SL, Liu KD, Longmore GD, Greene WC, Goldsmith MA. PMID: 8552611; PMCID: PMC40212.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Interaction of HTLV-I Tax with the human proteasome: implications for NF-kappa B induction. J Acquir Immune Defic Syndr Hum Retrovirol. 1996; 13 Suppl 1:S76-84.
Béraud C, Greene WC. PMID: 8797708.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require Shc phosphorylation or receptor association. J Biol Chem. 1995 Dec 01; 270(48):28858-63.
Evans GA, Goldsmith MA, Johnston JA, Xu W, Weiler SR, Erwin R, Howard OM, Abraham RT, O'Shea JJ, Greene WC, et al. PMID: 7499411.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Predicting progression to AIDS. Ann Intern Med. 1995 Nov 01; 123(9):726-7.
Greene WC. PMID: 7574230.
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PubMed Mentions: Fields:
Translation:
Humans
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Identification of a variable region within the cytoplasmic tail of the IL-2 receptor beta chain that is required for growth signal transduction. J Biol Chem. 1995 Sep 22; 270(38):22176-81.
Liu KD, Lai SY, Goldsmith MA, Greene WC. PMID: 7545674.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain. J Biol Chem. 1995 Sep 15; 270(37):21729-37.
Goldsmith MA, Lai SY, Xu W, Amaral MC, Kuczek ES, Parent LJ, Mills GB, Tarr KL, Longmore GD, Greene WC. PMID: 7665592.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity. Proc Natl Acad Sci U S A. 1995 Aug 01; 92(16):7192-6.
Gaffen SL, Lai SY, Xu W, Gouilleux F, Groner B, Goldsmith MA, Greene WC. PMID: 7543676; PMCID: PMC41305.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef. J Virol. 1995 Jul; 69(7):4112-21.
Goldsmith MA, Warmerdam MT, Atchison RE, Miller MD, Greene WC. PMID: 7769669; PMCID: PMC189146.
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PubMed Mentions:
81 Fields:
Translation:
HumansCells
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Ligand binding by the IL-2 receptor is modulated by intracellular determinants of the IL-2 receptor beta-chain. J Immunol. 1995 Mar 01; 154(5):2033-40.
Goldsmith MA, Amaral MC, Greene WC. PMID: 7868880.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry. J Virol. 1995 Jan; 69(1):579-84.
Miller MD, Warmerdam MT, Page KA, Feinberg MB, Greene WC. PMID: 7983759; PMCID: PMC188614.
View in:
PubMed Mentions:
63 Fields:
Translation:
HumansCells
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Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene. Mol Cell Biol. 1994 Nov; 14(11):7377-84.
Sun SC, Elwood J, Béraud C, Greene WC. PMID: 7935451; PMCID: PMC359272.
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PubMed Mentions:
81 Fields:
Translation:
HumansCells
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The HIV-1 nef gene acts as a positive viral infectivity factor. Trends Microbiol. 1994 Aug; 2(8):294-8.
Miller MD, Feinberg MB, Greene WC. PMID: 7981973.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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The cytoplasmic domain of the interleukin-2 receptor beta chain contains both unique and functionally redundant signal transduction elements. J Biol Chem. 1994 May 20; 269(20):14698-704.
Goldsmith MA, Xu W, Amaral MC, Kuczek ES, Greene WC. PMID: 8182077.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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The membrane proximal segment of the IL-2 receptor beta-chain acidic region is essential for IL2-dependent protein tyrosine kinase activation. Leukemia. 1994 Apr; 8 Suppl 1:S186-9.
Williamson P, Merida I, Greene WC, Gaulton G. PMID: 8152289.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Autoregulation of the NF-kappa B transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs. Proc Natl Acad Sci U S A. 1994 Feb 15; 91(4):1346-50.
Sun SC, Ganchi PA, Béraud C, Ballard DW, Greene WC. PMID: 8108414; PMCID: PMC43155.
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PubMed Mentions:
83 Fields:
Translation:
HumansCells
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Human T-cell leukemia virus type I Tax associates with and is negatively regulated by the NF-kappa B2 p100 gene product: implications for viral latency. Mol Cell Biol. 1994 Feb; 14(2):1374-82.
Béraud C, Sun SC, Ganchi P, Ballard DW, Greene WC. PMID: 8289813; PMCID: PMC358492.
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PubMed Mentions:
53 Fields:
Translation:
HumansAnimalsCells
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The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages. J Exp Med. 1994 Jan 01; 179(1):101-13.
Miller MD, Warmerdam MT, Gaston I, Greene WC, Feinberg MB. PMID: 8270859; PMCID: PMC2191317.
View in:
PubMed Mentions:
233 Fields:
Translation:
HumansCells
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A novel NF-kappa B complex containing p65 homodimers: implications for transcriptional control at the level of subunit dimerization. Mol Cell Biol. 1993 Dec; 13(12):7826-35.
Ganchi PA, Sun SC, Greene WC, Ballard DW. PMID: 8246997; PMCID: PMC364854.
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PubMed Mentions:
44 Fields:
Translation:
HumansAnimalsCells
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Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function. EMBO J. 1993 Oct; 12(10):3879-91.
Stein B, Baldwin AS, Ballard DW, Greene WC, Angel P, Herrlich P. PMID: 8404856; PMCID: PMC413671.
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PubMed Mentions:
157 Fields:
Translation:
HumansAnimalsCells
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AIDS and the immune system. Sci Am. 1993 Sep; 269(3):98-105.
Greene WC. PMID: 8211096.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Dominant negative mutants of human T-cell leukemia virus type I Rex and human immunodeficiency virus type 1 Rev fail to multimerize in vivo. J Virol. 1993 May; 67(5):2496-502.
Bogerd H, Greene WC. PMID: 8474155; PMCID: PMC237568.
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PubMed Mentions:
39 Fields:
Translation:
Cells
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Unexpected effects of the IL-2 receptor alpha subunit on high affinity IL-2 receptor assembly and function detected with a mutant IL-2 analog. J Immunol. 1993 Apr 15; 150(8 Pt 1):3357-65.
Kuziel WA, Ju G, Grdina TA, Greene WC. PMID: 8468475.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway. Science. 1993 Mar 26; 259(5103):1912-5.
Sun SC, Ganchi PA, Ballard DW, Greene WC. PMID: 8096091.
View in:
PubMed Mentions:
439 Fields:
Translation:
HumansCells
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The serine-rich cytoplasmic domain of the interleukin-2 receptor beta chain is essential for interleukin-2-dependent tyrosine protein kinase and phosphatidylinositol-3-kinase activation. J Biol Chem. 1993 Mar 25; 268(9):6765-70.
Merida I, Williamson P, Kuziel WA, Greene WC, Gaulton GN. PMID: 8384218.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Multiple arginine residues within the basic domain of HTLV-I Rex are required for specific RNA binding and function. Virology. 1993 Mar; 193(1):41-9.
Hammes SR, Greene WC. PMID: 8438577.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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The c-rel protooncogene product represses NF-kappa B p65-mediated transcriptional activation of the long terminal repeat of type 1 human immunodeficiency virus. Proc Natl Acad Sci U S A. 1993 Feb 01; 90(3):1023-7.
Doerre S, Sista P, Sun SC, Ballard DW, Greene WC. PMID: 8430069; PMCID: PMC45803.
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PubMed Mentions:
32 Fields:
Translation:
HumansCells
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I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding. Mol Biol Cell. 1992 Dec; 3(12):1339-52.
Ganchi PA, Sun SC, Greene WC, Ballard DW. PMID: 1493333; PMCID: PMC275704.
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PubMed Mentions:
101 Fields:
Translation:
HumansAnimalsCells
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Neither the LCK nor the FYN kinases are obligatory for IL-2-mediated signal transduction in HTLV-I-infected human T cells. Int Immunol. 1992 Nov; 4(11):1233-43.
Mills GB, Arima N, May C, Hill M, Schmandt R, Li J, Miyamoto NG, Greene WC. PMID: 1472476.
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PubMed Mentions:
11 Fields:
Translation:
Cells
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Molecular insights into human immunodeficiency virus type 1 pathogenesis. Curr Opin Immunol. 1992 Aug; 4(4):466-74.
Feinberg MB, Greene WC. PMID: 1356348.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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The v-rel oncogene: insights into the mechanism of transcriptional activation, repression, and transformation. J Virol. 1992 Aug; 66(8):5018-29.
Walker WH, Stein B, Ganchi PA, Hoffman JA, Kaufman PA, Ballard DW, Hannink M, Greene WC. PMID: 1321284; PMCID: PMC241358.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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IL-2-induced signal transduction involves the activation of nuclear NF-kappa B expression. J Immunol. 1992 Jul 01; 149(1):83-91.
Arima N, Kuziel WA, Grdina TA, Greene WC. PMID: 1607664.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Nuclear expression of the 50- and 65-kD Rel-related subunits of nuclear factor-kappa B is differentially regulated in human monocytic cells. J Clin Invest. 1992 Jul; 90(1):121-9.
Kaufman PA, Weinberg JB, Greene WC. PMID: 1634604; PMCID: PMC443070.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Dominant-negative mutants are clustered in a domain of the human T-cell leukemia virus type I Rex protein: implications for trans dominance. J Virol. 1992 Jul; 66(7):4540-5.
Weichselbraun I, Berger J, Dobrovnik M, Bogerd H, Grassmann R, Greene WC, Hauber J, Böhnlein E. PMID: 1602559; PMCID: PMC241265.
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PubMed Mentions:
16 Fields:
Translation:
Cells
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The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression. Proc Natl Acad Sci U S A. 1992 Mar 01; 89(5):1875-9.
Ballard DW, Dixon EP, Peffer NJ, Bogerd H, Doerre S, Stein B, Greene WC. PMID: 1542686; PMCID: PMC48556.
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PubMed Mentions:
111 Fields:
Translation:
HumansCells
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Characterization of a novel nuclear localization signal in the HTLV-I tax transactivator protein. Virology. 1992 Mar; 187(1):316-20.
Smith MR, Greene WC. PMID: 1736534.
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PubMed Mentions:
56 Fields:
Translation:
Cells
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Human T-cell leukemia virus type I Tax induces expression of the Rel-related family of kappa B enhancer-binding proteins: evidence for a pretranslational component of regulation. J Virol. 1991 Dec; 65(12):6892-9.
Arima N, Molitor JA, Smith MR, Kim JH, Daitoku Y, Greene WC. PMID: 1719236; PMCID: PMC250789.
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PubMed Mentions:
41 Fields:
Translation:
HumansCells
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Kappa B-specific DNA binding proteins are differentially inhibited by enhancer mutations and biological oxidation. New Biol. 1991 Oct; 3(10):987-96.
Molitor JA, Ballard DW, Greene WC. PMID: 1768652.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Type I human T cell leukemia virus tax protein transforms rat fibroblasts through the cyclic adenosine monophosphate response element binding protein/activating transcription factor pathway. J Clin Invest. 1991 Sep; 88(3):1038-42.
Smith MR, Greene WC. PMID: 1832173; PMCID: PMC295515.
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PubMed Mentions:
50 Fields:
Translation:
AnimalsCells
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The type I human T-cell leukemia virus (HTLV-I) Rex trans-activator binds directly to the HTLV-I Rex and the type 1 human immunodeficiency virus Rev RNA response elements. Proc Natl Acad Sci U S A. 1991 Jul 01; 88(13):5704-8.
Bogerd HP, Huckaby GL, Ahmed YF, Hanly SM, Greene WC. PMID: 1905815; PMCID: PMC51946.
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PubMed Mentions:
48 Fields:
Translation:
Cells
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A member of the set of kappa B binding proteins, HIVEN86A, is a product of the human c-rel proto-oncogene. Oncogene. 1991 Apr; 6(4):665-7.
Lee JH, Li YC, Doerre S, Sista P, Ballard DW, Greene WC, Franza BR. PMID: 2030915.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Kappa B binding proteins are constitutively expressed in an IL-2 autocrine human T cell line. J Immunol. 1991 Apr 01; 146(7):2409-16.
Hémar A, Cereghini S, Cornet V, Blank V, Israël A, Greene WC, Dautry-Varsat A. PMID: 2005404.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Molecular biology of the type I human T-cell leukemia virus (HTLV-I) and adult T-cell leukemia. J Clin Invest. 1991 Mar; 87(3):761-6.
Smith MR, Greene WC. PMID: 1999493; PMCID: PMC329862.
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PubMed Mentions:
50 Fields:
Translation:
HumansCells
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The HTLV-I Rex response element mediates a novel form of mRNA polyadenylation. Cell. 1991 Feb 22; 64(4):727-37.
Ahmed YF, Gilmartin GM, Hanly SM, Nevins JR, Greene WC. PMID: 1671761.
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PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
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The molecular biology of human immunodeficiency virus type 1 infection. N Engl J Med. 1991 Jan 31; 324(5):308-17.
Greene WC. PMID: 1986289.
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PubMed Mentions:
48 Fields:
Translation:
Cells
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Functional analyses of the type I human T-cell leukemia virus tax gene product. Trans Assoc Am Physicians. 1991; 104:78-91.
Smith MR, Greene WC. PMID: 1845158.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Rex transregulation of human T-cell leukemia virus type II gene expression. J Virol. 1991 Jan; 65(1):405-14.
Kim JH, Kaufman PA, Hanly SM, Rimsky LT, Greene WC. PMID: 1985205; PMCID: PMC240531.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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NF-kappa B: a family of inducible and differentially expressed enhancer-binding proteins in human T cells. Proc Natl Acad Sci U S A. 1990 Dec; 87(24):10028-32.
Molitor JA, Walker WH, Doerre S, Ballard DW, Greene WC. PMID: 2263603; PMCID: PMC55308.
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PubMed Mentions:
86 Fields:
Translation:
HumansCells
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The v-rel oncogene encodes a kappa B enhancer binding protein that inhibits NF-kappa B function. Cell. 1990 Nov 16; 63(4):803-14.
Ballard DW, Walker WH, Doerre S, Sista P, Molitor JA, Dixon EP, Peffer NJ, Hannink M, Greene WC. PMID: 2225078.
View in:
PubMed Mentions:
142 Fields:
Translation:
HumansCells
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Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes. Genes Dev. 1990 Nov; 4(11):1875-85.
Smith MR, Greene WC. PMID: 2276622.
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PubMed Mentions:
183 Fields:
Translation:
HumansAnimalsCells
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Functions of the auxiliary gene products of the human immunodeficiency virus type 1. Virology. 1990 Sep; 178(1):1-5.
Cullen BR, Greene WC. PMID: 2202146.
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PubMed Mentions:
47 Fields:
Translation:
HumansCells
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The molecular basis for the generation of the human soluble interleukin 2 receptor. Cytokine. 1990 Sep; 2(5):330-6.
Rubin LA, Galli F, Greene WC, Nelson DL, Jay G. PMID: 2103332.
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PubMed Mentions:
30 Translation:
HumansAnimalsCells
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Interleukin-2 and the IL-2 receptor: new insights into structure and function. J Invest Dermatol. 1990 Jun; 94(6 Suppl):27S-32S.
Kuziel WA, Greene WC. PMID: 1693645.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Structure-function analyses of the HTLV-I Rex and HIV-1 Rev RNA response elements: insights into the mechanism of Rex and Rev action. Genes Dev. 1990 Jun; 4(6):1014-22.
Ahmed YF, Hanly SM, Malim MH, Cullen BR, Greene WC. PMID: 2116986.
View in:
PubMed Mentions:
66 Fields:
Translation:
AnimalsCells
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The human interleukin-2 receptor: insights into subunit structure and growth signal transduction. Semin Immunol. 1990 Mar; 2(2):119-28.
Fung MR, Greene WC. PMID: 2129904.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Interleukin 2-induced tyrosine phosphorylation. Interleukin 2 receptor beta is tyrosine phosphorylated. J Biol Chem. 1990 Feb 25; 265(6):3561-7.
Mills GB, May C, McGill M, Fung M, Baker M, Sutherland R, Greene WC. PMID: 2303462.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Regulation of HIV-1 gene expression. Annu Rev Immunol. 1990; 8:453-75.
Greene WC. PMID: 2188670.
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PubMed Mentions:
47 Fields:
Translation:
HumansCells
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A second sequence element located 3' to the NF-kappa B-binding site regulates IL-2 receptor-alpha gene induction. J Immunol. 1989 Dec 15; 143(12):4275-81.
Pomerantz JL, Mauxion F, Yoshida M, Greene WC, Sen R. PMID: 2687377.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Nef protein of human immunodeficiency virus type 1: evidence against its role as a transcriptional inhibitor. Proc Natl Acad Sci U S A. 1989 Dec; 86(23):9549-53.
Hammes SR, Dixon EP, Malim MH, Cullen BR, Greene WC. PMID: 2687884; PMCID: PMC298534.
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PubMed Mentions:
78 Fields:
Translation:
AnimalsCells
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The same 50-kDa cellular protein binds to the negative regulatory elements of the interleukin 2 receptor alpha-chain gene and the human immunodeficiency virus type 1 long terminal repeat. Proc Natl Acad Sci U S A. 1989 Nov; 86(21):8526-30.
Smith MR, Greene WC. PMID: 2813410; PMCID: PMC298315.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansCells
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Trans-dominant inactivation of HTLV-I and HIV-1 gene expression by mutation of the HTLV-I Rex transactivator. Nature. 1989 Oct 05; 341(6241):453-6.
Rimsky L, Dodon MD, Dixon EP, Greene WC. PMID: 2677743.
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PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements. Genes Dev. 1989 Oct; 3(10):1534-44.
Hanly SM, Rimsky LT, Malim MH, Kim JH, Hauber J, Duc Dodon M, Le SY, Maizel JV, Cullen BR, Greene WC. PMID: 2482226.
View in:
PubMed Mentions:
103 Fields:
Translation:
Cells
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Activation of the interleukin-2 receptor alpha gene: regulatory role for DNA-protein interactions flanking the kappa B enhancer. New Biol. 1989 Oct; 1(1):83-92.
Ballard DW, Böhnlein E, Hoffman JA, Bogerd HP, Dixon EP, Franza BR, Greene WC. PMID: 2518691.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Regulatory pathways governing HIV-1 replication. Cell. 1989 Aug 11; 58(3):423-6.
Cullen BR, Greene WC. PMID: 2569361.
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PubMed Mentions:
148 Fields:
Translation:
HumansCells
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HIV-1, HTLV-1 and normal T-cell growth: transcriptional strategies and surprises. Immunol Today. 1989 Aug; 10(8):272-8.
Greene WC, Böhnlein E, Ballard DW. PMID: 2679647.
View in:
PubMed Mentions:
40 Fields:
Translation:
HumansCells
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Induction of interleukin-2 receptor-alpha gene expression is regulated by post-translational activation of kappa B specific DNA binding proteins. J Biol Chem. 1989 May 25; 264(15):8475-8.
Böhnlein E, Ballard DW, Bogerd H, Peffer NJ, Lowenthal JW, Greene WC. PMID: 2785992.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Tumor necrosis factor-alpha activation of the IL-2 receptor-alpha gene involves the induction of kappa B-specific DNA binding proteins. J Immunol. 1989 May 01; 142(9):3121-8.
Lowenthal JW, Ballard DW, Bogerd H, Böhnlein E, Greene WC. PMID: 2785134.
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PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Kappa B-specific DNA binding proteins: role in the regulation of human interleukin-2 gene expression. Science. 1989 Apr 28; 244(4903):457-60.
Hoyos B, Ballard DW, Böhnlein E, Siekevitz M, Greene WC. PMID: 2497518.
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PubMed Mentions:
110 Fields:
Translation:
HumansCells
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Stimulation of the human immunodeficiency virus type 1 enhancer by the human T-cell leukemia virus type I tax gene product involves the action of inducible cellular proteins. J Virol. 1989 Apr; 63(4):1578-86.
Böhnlein E, Siekevitz M, Ballard DW, Lowenthal JW, Rimsky L, Bogérd H, Hoffman J, Wano Y, Franza BR, Greene WC. PMID: 2784507; PMCID: PMC248395.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansCells
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Tumor necrosis factor alpha induces proteins that bind specifically to kappa B-like enhancer elements and regulate interleukin 2 receptor alpha-chain gene expression in primary human T lymphocytes. Proc Natl Acad Sci U S A. 1989 Apr; 86(7):2331-5.
Lowenthal JW, Ballard DW, Böhnlein E, Greene WC. PMID: 2494663; PMCID: PMC286906.
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PubMed Mentions:
77 Fields:
Translation:
HumansCells
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HIV-1, HTLV-I and the interleukin-2 receptor: insights into transcriptional control. Haematol Blood Transfus. 1989; 32:393-401.
Böhnlein E, Lowenthal JW, Wano Y, Franza BR, Ballard DW, Greene WC. PMID: 2625257.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Stable expression of the tax gene of type I human T-cell leukemia virus in human T cells activates specific cellular genes involved in growth. Proc Natl Acad Sci U S A. 1988 Dec; 85(24):9733-7.
Wano Y, Feinberg M, Hosking JB, Bogerd H, Greene WC. PMID: 3059351; PMCID: PMC282853.
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PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
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Co-internalization of the p55 and p70 subunits of the high-affinity human interleukin 2 receptor. Evidence for a stable ternary receptor complex. J Exp Med. 1988 Nov 01; 168(5):1923-8.
Fung MR, Ju G, Greene WC. PMID: 3263468; PMCID: PMC2189118.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein. Nature. 1988 Oct 20; 335(6192):738-40.
Rimsky L, Hauber J, Dukovich M, Malim MH, Langlois A, Cullen BR, Greene WC. PMID: 3262832.
View in:
PubMed Mentions:
98 Fields:
Translation:
Cells
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Identification of specific residues of human interleukin 2 that affect binding to the 70-kDa subunit (p70) of the interleukin 2 receptor. Proc Natl Acad Sci U S A. 1988 Oct; 85(20):7709-13.
Collins L, Tsien WH, Seals C, Hakimi J, Weber D, Bailon P, Hoskings J, Greene WC, Toome V, Ju G. PMID: 3051003; PMCID: PMC282262.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene. Science. 1988 Sep 23; 241(4873):1652-5.
Ballard DW, Böhnlein E, Lowenthal JW, Wano Y, Franza BR, Greene WC. PMID: 2843985.
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PubMed Mentions:
201 Fields:
Translation:
Cells
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p55 IL-2 receptor mRNA precursors in murine T lymphocyte nuclei. J Immunol. 1988 Aug 15; 141(4):1358-64.
Froussard P, Chastagner P, Sommé G, Abadie A, Greene W, Thèze J, Longacre S. PMID: 3135330.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV. Cell. 1988 Jun 03; 53(5):827-36.
Böhnlein E, Lowenthal JW, Siekevitz M, Ballard DW, Franza BR, Greene WC. PMID: 2836068.
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PubMed Mentions:
171 Fields:
Translation:
Cells
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Regulation of interleukin 2 receptor alpha subunit (Tac or CD25 antigen) gene expression: binding of inducible nuclear proteins to discrete promoter sequences correlates with transcriptional activation. Proc Natl Acad Sci U S A. 1988 Jun; 85(12):4468-72.
Lowenthal JW, Böhnlein E, Ballard DW, Greene WC. PMID: 3132714; PMCID: PMC280451.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Sequence requirements for ligand binding and cell surface expression of the Tac antigen, a human interleukin-2 receptor. J Biol Chem. 1988 Apr 05; 263(10):4900-6.
Cullen BR, Podlaski FJ, Peffer NJ, Hosking JB, Greene WC. PMID: 2832410.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Sarcoidosis and interleukin-2 receptors. Am Rev Respir Dis. 1988 Apr; 137(4):757-8.
Greene WC. PMID: 2833139.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Lymphocytes isolated from the intestinal lamina propria of normal nonhuman primates have increased expression of genes associated with T-cell activation. Gastroenterology. 1988 Mar; 94(3):647-55.
Zeitz M, Greene WC, Peffer NJ, James SP. PMID: 3123303.
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PubMed Mentions:
45 Fields:
Translation:
AnimalsCells
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Novel interleukin 2 (IL-2) receptor appears to mediate IL-2-induced activation of natural killer cells. J Clin Invest. 1988 Jan; 81(1):200-5.
Kehrl JH, Dukovich M, Whalen G, Katz P, Fauci AS, Greene WC. PMID: 2826541; PMCID: PMC442494.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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The human interleukin-2 receptor. Recent studies of structure and regulation. Ann N Y Acad Sci. 1988; 546:116-21.
Greene WC, Böhnlein E, Siekevitz M, Franza BR, Lowenthal J. PMID: 3073691.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
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New insights into the structure of high-affinity interleukin-2 receptors. Recent Prog Horm Res. 1988; 44:141-55.
Greene WC, Wano YJ, Dukovich M. PMID: 3064206.
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PubMed Mentions: Fields:
Translation:
Animals
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In: Smith KA (Ed.), Interleukin 2. New perspectives on the structure of the human high affinity i nterleukin-2 receptor. 1988; 99-112.
Wano Y, Dukovich M, Kehrl JH, Greene WC.
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In: Gallin J, Goldstein I, Snyderman R (Eds.), Inflammation: Basic principles and clinical correlations. IL-2, IL-2 receptors, and the growth of human T cells. 1988; 209-288.
Greene WC.
-
Activation of the HIV-1 LTR by T cell mitogens and the trans-activator protein of HTLV-I. Science. 1987 Dec 11; 238(4833):1575-8.
Siekevitz M, Josephs SF, Dukovich M, Peffer N, Wong-Staal F, Greene WC. PMID: 2825351.
View in:
PubMed Mentions:
184 Fields:
Translation:
Cells
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Contrasting interleukin 2 binding properties of the alpha (p55) and beta (p70) protein subunits of the human high-affinity interleukin 2 receptor. J Exp Med. 1987 Oct 01; 166(4):1156-61.
Lowenthal JW, Greene WC. PMID: 3116145; PMCID: PMC2188735.
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31 Fields:
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Reconstitution of a functional interleukin 2 receptor in a nonlymphoid cell. J Immunol. 1987 Oct 01; 139(7):2355-60.
Rubin LA, Hoekzema GS, Nelson DL, Greene WC, Jay G. PMID: 2821112.
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3 Fields:
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Direct activation of human resting T cells by IL 2: the role of an IL 2 receptor distinct from the Tac protein. J Immunol. 1987 Sep 01; 139(5):1550-6.
Bich-Thuy LT, Dukovich M, Peffer NJ, Fauci AS, Kehrl JH, Greene WC. PMID: 3040856.
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49 Fields:
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Interleukin 1 gene expression in adult T cell leukemia. J Clin Invest. 1987 Sep; 80(3):911-6.
Wano Y, Hattori T, Matsuoka M, Takatsuki K, Chua AO, Gubler U, Greene WC. PMID: 2887587; PMCID: PMC442321.
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38 Fields:
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The human interleukin-2 receptor: a molecular and biochemical analysis of structure and function. Clin Res. 1987 Sep; 35(5):439-50.
Greene WC. PMID: 2889557.
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11 Fields:
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Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I. Proc Natl Acad Sci U S A. 1987 Aug; 84(15):5389-93.
Siekevitz M, Feinberg MB, Holbrook N, Wong-Staal F, Greene WC. PMID: 3037548; PMCID: PMC298861.
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151 Fields:
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A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors. Nature. 1987 Jun 11-17; 327(6122):518-22.
Dukovich M, Wano Y, Katz P, Cullen BR, Kehrl JH, Greene WC. PMID: 3108674.
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75 Fields:
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Expression of functional IL 2 receptors by lipopolysaccharide and interferon-gamma stimulated human monocytes. J Immunol. 1987 May 01; 138(9):2917-22.
Holter W, Goldman CK, Casabo L, Nelson DL, Greene WC, Waldmann TA. PMID: 3106493.
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50 Fields:
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Reconstitution of high affinity IL-2 receptor expression in a human T-cell line using a retroviral cDNA expression vector. Mol Biol Med. 1987 Apr; 4(2):95-109.
Wano Y, Cullen BR, Svetlik PA, Peffer NJ, Greene WC. PMID: 3114593.
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4 Fields:
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High-affinity interleukin 2 binding by an oncogenic hybrid interleukin 2-epidermal growth factor receptor molecule. Proc Natl Acad Sci U S A. 1987 Apr; 84(8):2125-9.
Bernard O, Fazekas de St Groth B, Ullrich A, Green W, Schlessinger J. PMID: 3104909; PMCID: PMC304601.
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5 Fields:
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Internalization of interleukin 2 is mediated by the beta chain of the high-affinity interleukin 2 receptor. J Exp Med. 1987 Apr 01; 165(4):1201-6.
Robb RJ, Greene WC. PMID: 3031195; PMCID: PMC2188578.
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56 Fields:
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Interleukin 2 binding molecule distinct from the Tac protein: analysis of its role in formation of high-affinity receptors. Proc Natl Acad Sci U S A. 1987 Apr; 84(7):2002-6.
Robb RJ, Rusk CM, Yodoi J, Greene WC. PMID: 3031660; PMCID: PMC304571.
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68 Fields:
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Trans-activator gene of HTLV-II: interpretation. Science. 1987 Feb 27; 235(4792):1073.
Greene WC, Leonard WJ, Wano Y, Svetlik PB, Peffer NJ, Sodroski JG, Rosen CA, Goh WC, Haseltine WA. PMID: 3029865.
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1 Fields:
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Human interleukin 2 receptor (Tac antigen). Methods Enzymol. 1987; 150:682-700.
Greene WC, Leonard WJ. PMID: 3123879.
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An overview of the human interleukin-2 receptor: molecular, biochemical, and functional properties. Cancer Invest. 1987; 5(4):369-76.
Greene WC. PMID: 2889515.
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1 Fields:
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In: Webb DR, Pierce CW, Cohen S (Eds.), Proceedings of the Fifth International Lymphokine Workshop. The human high affinity for interleukin-2 receptor. 1987; 171-179.
Greene WC, Dukovich M, Wano Y, Kehrl JH, Robb RJ.
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In: Pruzanki W, Seligmann M (Eds.), Clinical Immunology. The transactivator (tat) gene of HTLV-II induces the expression of cellular genes involved in T cell growth. 1987; 213-216.
Greene WC, Leonard WJ, Wano Y, Sodroski JG, Rosen CA, Haseltine WA.
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Int. J. Immunother. III. Expression of interleukin-2 receptors in normal and neoplastic T cells. 1987; 3:171-175.
Greene WC.
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Proceedings of the AACR 1987. IL-2, IL-2 receptors and human retroviruses. 1987; 469-470.
Greene WC.
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Expression of human interleukin-2 receptor cDNA in E. coli. Biochem Biophys Res Commun. 1986 Dec 15; 141(2):804-11.
Chanda PK, Chen GF, Baine Y, Leonard WJ, Greene WC, Chang TW, Chang NT. PMID: 3026392.
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Diltiazem inhibits transferrin receptor expression and causes G1 arrest in normal and neoplastic T cells. Mol Cell Biol. 1986 Dec; 6(12):4244-50.
Neckers LM, Bauer S, McGlennen RC, Trepel JB, Rao K, Greene WC. PMID: 2432398; PMCID: PMC367205.
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1 Fields:
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Characterization of the human interleukin 2 receptor at the DNA, RNA, and protein level. Immunobiology. 1986 Sep; 172(3-5):357-64.
Greene WC. PMID: 3100432.
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The human interleukin-2 receptor: analysis of structure and function. Immunol Rev. 1986 Aug; 92:29-48.
Greene WC, Depper JM, Krönke M, Leonard WJ. PMID: 3091481.
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6 Fields:
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Selective killing of human T-lymphotropic virus-I infected leukemic T-cells by monoclonal anti-interleukin 2 receptor antibody-ricin A chain conjugates: potentiation by ammonium chloride and monensin. Cancer Res. 1986 Jul; 46(7):3295-8.
Krönke M, Schlick E, Waldmann TA, Vitetta ES, Greene WC. PMID: 3011246.
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8 Fields:
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A secreted form of the human interleukin 2 receptor encoded by an "anchor minus" cDNA. J Immunol. 1986 Jun 01; 136(11):4099-105.
Treiger BF, Leonard WJ, Svetlik P, Rubin LA, Nelson DL, Greene WC. PMID: 3084654.
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12 Fields:
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Trans-activator gene of HTLV-II induces IL-2 receptor and IL-2 cellular gene expression. Science. 1986 May 16; 232(4752):877-80.
Greene WC, Leonard WJ, Wano Y, Svetlik PB, Peffer NJ, Sodroski JG, Rosen CA, Goh WC, Haseltine WA. PMID: 3010456.
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40 Fields:
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Only high-affinity receptors for interleukin 2 mediate internalization of ligand. Proc Natl Acad Sci U S A. 1986 Mar; 83(5):1463-6.
Weissman AM, Harford JB, Svetlik PB, Leonard WL, Depper JM, Waldmann TA, Greene WC, Klausner RD. PMID: 3081898; PMCID: PMC323096.
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42 Fields:
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The human interleukin-2 receptor. Annu Rev Immunol. 1986; 4:69-95.
Greene WC, Leonard WJ. PMID: 3011033.
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46 Fields:
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The human interleukin-2 receptor: role in normal T-cell growth and association with HTLV-I-induced T-cell leukemia. Cold Spring Harb Symp Quant Biol. 1986; 51 Pt 2:731-7.
Greene WC, Depper JM, Krönke M, Leonard WJ. PMID: 2884072.
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Growth of human T lymphocytes: an analysis of interleukin 2 and its cellular receptor. Prog Hematol. 1986; 14:283-301.
Greene WC, Leonard WJ, Depper JM. PMID: 2418464.
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12 Fields:
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The arrangement of immunoglobulin, T cell antigen receptor, and interleukin 2 receptor genes in human lymphoid neoplasms. Symp Fundam Cancer Res. 1986; 38:63-78.
Waldmann TA, Korsmeyer SJ, Greene WC. PMID: 3489263.
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In: Greene WC, moderator. The human interleukin-2 receptor: normal and abnormal expression in T cells and in leukemias induced by the human T lymphotropic retroviruses. Ann. Int. Med. Deregulated interleukin-2 receptor expression in Adult T-cell Leukemia. 1986; 105:566-569.
Greene WC.
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In: Pincus S, Pisetsky D, Rosenwasser L (Eds.), Biologically based immunomodulators in the therapy of rheumatic diseases. The human receptor for interleukin-2: characterization, controversies, and expression in rheumatic diseases. 1986; 297-306.
Depper JM, Leonard WJ, Greene WC.
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In: Marget M, Lang W, Gabler-Sandberger E (Eds.), Proceedings of the IXth International Congress of Infectious and Parasitic Diseases. The transactivator (tat) gene of HTLV-II activates IL-2 receptor, IL-2, and class II major histocompatibility complex cellular gene expression. 1986; 1:67-69.
Greene WC, Leonard WJ, Wano Y, Sodroski JG, Rosen CA, Haseltine WA.
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Structure of the human interleukin-2 receptor gene. Science. 1985 Nov 08; 230(4726):633-9.
Leonard WJ, Depper JM, Kanehisa M, Krönke M, Peffer NJ, Svetlik PB, Sullivan M, Greene WC. PMID: 2996141.
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57 Fields:
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Monoclonal antibody OKT11A inhibits and recombinant interleukin 2 (IL 2) augments expression of IL 2 receptors at a pretranslational level. J Immunol. 1985 Oct; 135(4):2478-82.
Reed JC, Greene WC, Hoover RG, Nowell PC. PMID: 3928749.
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5 Fields:
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Interleukin 2 receptor (Tac antigen) expression in HTLV-I-associated adult T-cell leukemia. Cancer Res. 1985 Sep; 45(9 Suppl):4559s-4562s.
Waldmann TA, Longo DL, Leonard WJ, Depper JM, Thompson CB, Krönke M, Goldman CK, Sharrow S, Bongiovanni K, Greene WC. PMID: 2990687.
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10 Fields:
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Isolation and expression of complementary DNAs encoding the human interleukin 2 receptor. Cancer Res. 1985 Sep; 45(9 Suppl):4563s-4567s.
Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik P, Peffer NJ, Waldmann TA, et al. PMID: 2990688.
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Interleukin 2 receptor gene expression in normal human T lymphocytes. Proc Natl Acad Sci U S A. 1985 Sep; 82(18):6281-5.
Leonard WJ, Krönke M, Peffer NJ, Depper JM, Greene WC. PMID: 3929255; PMCID: PMC391037.
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54 Fields:
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Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome. Evidence for a selective defect in soluble antigen recognition. N Engl J Med. 1985 Jul 11; 313(2):79-84.
Lane HC, Depper JM, Greene WC, Whalen G, Waldmann TA, Fauci AS. PMID: 2582258.
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174 Fields:
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Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells. J Exp Med. 1985 Jul 01; 162(1):363-8.
Greene WC, Robb RJ, Svetlik PB, Rusk CM, Depper JM, Leonard WJ. PMID: 2989411; PMCID: PMC2187706.
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30 Fields:
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Localization of the gene encoding the human interleukin-2 receptor on chromosome 10. Science. 1985 Jun 28; 228(4707):1547-9.
Leonard WJ, Donlon TA, Lebo RV, Greene WC. PMID: 3925551.
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18 Fields:
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Deregulation of interleukin-2 receptor gene expression in HTLV-I-induced adult T-cell leukemia. Science. 1985 Jun 07; 228(4704):1215-7.
Krönke M, Leonard WJ, Depper JM, Greene WC. PMID: 2988127.
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13 Fields:
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Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene. Proc Natl Acad Sci U S A. 1985 Jun; 82(12):4230-4.
Depper JM, Leonard WJ, Drogula C, Krönke M, Waldmann TA, Greene WC. PMID: 2987968; PMCID: PMC397970.
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100 Fields:
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Adult T cell leukemia: a potential target for ricin A chain immunotoxins. Blood. 1985 Jun; 65(6):1416-21.
Krönke M, Depper JM, Leonard WJ, Vitetta ES, Waldmann TA, Greene WC. PMID: 2986744.
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7 Fields:
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Nucleotide sequence and expression of a mouse interleukin 2 receptor cDNA. J Immunol. 1985 Jun; 134(6):4212-7.
Miller J, Malek TR, Leonard WJ, Greene WC, Shevach EM, Germain RN. PMID: 3921620.
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49 Fields:
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Sequential expression of genes involved in human T lymphocyte growth and differentiation. J Exp Med. 1985 Jun 01; 161(6):1593-8.
Krönke M, Leonard WJ, Depper JM, Greene WC. PMID: 2989408; PMCID: PMC2187631.
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74 Fields:
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The human receptor for T-cell growth factor. Evidence for variable post-translational processing, phosphorylation, sulfation, and the ability of precursor forms of the receptor to bind T-cell growth factor. J Biol Chem. 1985 Feb 10; 260(3):1872-80.
Leonard WJ, Depper JM, Krönke M, Robb RJ, Waldmann TA, Greene WC. PMID: 2981876.
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14 Fields:
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The human interleukin-2 receptor. J Cell Sci Suppl. 1985; 3:97-106.
Greene WC, Depper JM, Krönke M, Leonard WJ. PMID: 3938983.
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1 Fields:
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Activators of protein kinase C and 5-azacytidine induce IL-2 receptor expression on human T lymphocytes. J Cell Biochem. 1985; 27(3):267-76.
Depper JM, Leonard WJ, Drogula CL, Krönke M, Waldmann TA, Greene WC. PMID: 2580852.
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4 Fields:
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Molecular cloning of cDNA for the human interleukin-2 receptor. Haematol Blood Transfus. 1985; 29:388-95.
Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik P, Peffer NJ, Waldmann TA, et al. PMID: 2993133.
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Receptors for T-cell growth factor: structure, function and expression on normal and neoplastic cells. Contemp Top Mol Immunol. 1985; 10:1-34.
Greene WC, Robb RJ. PMID: 2983931.
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7 Fields:
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Effect of wheat germ agglutinin on the interleukin pathway of human T lymphocyte activation. J Immunol. 1985 Jan; 134(1):314-23.
Reed JC, Robb RJ, Greene WC, Nowell PC. PMID: 3917278.
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9 Fields:
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In: Feldmann M, Mitchison NA (Eds.), Immune Regulation. Molecular cloning and expression of cDNAs encoding the human interleukin-2 receptor. 1985; 185-195.
Leonard WJ, Depper JM, Crabtee GM, Rudikoff S, Pumphrey J, Robb RJ, Kronke M, Svetlik P, Peffer NJ, Waldmann TA, Greene WC.
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In: Pinchera A, Doria G, Dammacco F, Bargellesi A (Eds.), Monoclonal Antibodies 1984: Biological and Clinical Applications. Interleukin-2 receptors on lymphocytes. 1985; 329-338.
Waldmann TA, Leonard WJ, Depper JM, Kronke M, Goldman CK, Sharrow S, Greene WC.
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In: Sorg C, Schimple A (Eds.), Cellular and molecular biology of lymphokines. Cyclosporin A inhibits expression of select T-cell activation genes. 1985; 647-652.
Kronke M, Depper JM, Leonard WJ, Wong-Staal F, Gallo RC, Waldmann TA, Greene WC.
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In: Pattengale PK, Lukes RJ, Taylor CR (Eds.), Lymphoproliferative Diseases: Pathogenesis, Diagnosis, and Therapy. Molecular analysis of the human interleukin-2 receptor. 1985; 8-20.
Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Kronke M, Svetlik P, Peffer NJ, Waldmann TA, Leonard WJ.
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In: Sorg C, Schimple A (Eds.), Cellular and molecular biology of lymphokines. Cloning of cDNAs for the human interleukin-2 receptor and determination of its complete protein sequence. 1985; 623-633.
Leonard WJ, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Kronke M, Svetlik P, Peffer NJ, Waldmann TA, Greene WC.
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In: Feldman M (Ed.), Human T cell clones: An approach to immune regulation. Interleukin-2 receptors. 1985; 285-300.
Waldmann TA, Leonard WJ, Depper JM, Kronke M, Goldman CK, Bongiovani KF, Greene WC.
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In: Cancer Cells 3: Growth factors and transformation. Structure, function, and expression of the receptor for interleukin-2 on normal and malignant lymphocytes. 1985; 221-226.
Waldmann TA, Leonard WJ, Depper JM, Kronke M, Kozak R, Greene WC.
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In: Sorg P, Schimple A (Eds.), Cellular and molecular biology of lymphokines. The role of protein kinase C, and effects of 5-azacytidine on regulation on interleukin-2 receptor expression. 1985; 151-156.
Depper JM, Leonard WJ, Kronke M, Waldmann TA, Greene WC.
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Cellular origin of hairy cell leukemia: malignant B cells that express receptors for T cell growth factor. Semin Oncol. 1984 Dec; 11(4):394-400.
Korsmeyer SJ, Greene WC, Waldmann TA. PMID: 6438801.
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3 Fields:
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Regulation of interleukin 2 receptor expression: effects of phorbol diester, phospholipase C, and reexposure to lectin or antigen. J Immunol. 1984 Dec; 133(6):3054-61.
Depper JM, Leonard WJ, Krönke M, Noguchi PD, Cunningham RE, Waldmann TA, Greene WC. PMID: 6092466.
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47 Fields:
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Expression of interleukin 2 receptors on activated human B cells. J Exp Med. 1984 Nov 01; 160(5):1450-66.
Waldmann TA, Goldman CK, Robb RJ, Depper JM, Leonard WJ, Sharrow SO, Bongiovanni KF, Korsmeyer SJ, Greene WC. PMID: 6092511; PMCID: PMC2187491.
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96 Fields:
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Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen. J Exp Med. 1984 Oct 01; 160(4):1126-46.
Robb RJ, Greene WC, Rusk CM. PMID: 6090574; PMCID: PMC2187485.
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188 Fields:
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Augmented T cell growth factor receptor expression in HTLV-1-infected human leukemic T cells. J Immunol. 1984 Oct; 133(4):1691-5.
Depper JM, Leonard WJ, Krönke M, Waldmann TA, Greene WC. PMID: 6088625.
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39 Fields:
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Molecular cloning and expression of cDNAs for the human interleukin-2 receptor. Nature. 1984 Oct 18-24; 311(5987):626-31.
Leonard WJ, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik PB, Peffer NJ, Waldmann TA, et al. PMID: 6090948.
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206 Fields:
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Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription. Proc Natl Acad Sci U S A. 1984 Aug; 81(16):5214-8.
Krönke M, Leonard WJ, Depper JM, Arya SK, Wong-Staal F, Gallo RC, Waldmann TA, Greene WC. PMID: 6332315; PMCID: PMC391668.
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148 Fields:
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Phorbol diester induces expression of Tac antigen on human acute T lymphocytic leukemic cells. J Immunol. 1984 Aug; 133(2):1042-7.
Greene WC, Robb RJ, Depper JM, Leonard WJ, Drogula C, Svetlik PB, Wong-Staal F, Gallo RC, Waldmann TA. PMID: 6330200.
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12 Fields:
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Functional and phenotypic comparison of human T cell leukemia/lymphoma virus positive adult T cell leukemia with human T cell leukemia/lymphoma virus negative Sézary leukemia, and their distinction using anti-Tac. Monoclonal antibody identifying the human receptor for T cell growth factor. J Clin Invest. 1984 Jun; 73(6):1711-8.
Waldmann TA, Greene WC, Sarin PS, Saxinger C, Blayney DW, Blattner WA, Goldman CK, Bongiovanni K, Sharrow S, Depper JM, et al. PMID: 6327770; PMCID: PMC437083.
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31 Fields:
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Interleukin-2 receptor expression in retrovirus associated adult T-cell leukemia. Princess Takamatsu Symp. 1984; 15:259-68.
Waldmann TA, Leonard WJ, Depper JM, Krönke M, Goldman CK, Oh T, Greene WC. PMID: 6100644.
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3 Fields:
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Expression of receptors for interleukin 2: Role in the commitment of T lymphocytes to proliferate. J Immunol. 1984 Jan; 132(1):31-7.
Lipkowitz S, Greene WC, Rubin AL, Novogrodsky A, Stenzel KH. PMID: 6418801.
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17 Fields:
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Interleukin-2 receptors on activated malignant and normal B-cells. Curr Top Microbiol Immunol. 1984; 113:96-101.
Waldmann TA, Goldman CK, Leonard WJ, Depper JM, Robb RJ, Korsmeyer SJ, Greene WC. PMID: 6236954.
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2 Fields:
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HumansAnimalsCells
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In: Greaves M (Ed.), Receptors and Recognition. A monoclonal antibody to the human receptor for T cell growth factor. 1984; 17:45-66.
Leonard WJ, Depper JM, Waldmann TA, Greene WC.
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In: Sasazuki T (Ed.), Immunogenetics: Its application to clinical medicine. Cell-cell interactions in the human immune response: Analysis of leukemic T calls with immunoregulatory functions. 1984; 137-142.
Waldmann TA, Broder S, Greene WC.
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In: Pick E (Ed.), Lymphokines. A monoclonal antibody which recognizes the human receptor for T cell growth factor: Functional effects and use as a probe to investigate receptor regulation. 1984; 9:127-152.
Depper JM, Leonard WJ, Waldmann TA, Greene WC.
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Monoclonal lupus autoantibody secretion by human-human hybridomas. Selection of hybrids by conventional and novel techniques. J Clin Invest. 1983 Dec; 72(6):1987-94.
Littman BH, Muchmore AV, Steinberg AD, Greene WC. PMID: 6605979; PMCID: PMC437039.
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3 Fields:
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Characterization of the human receptor for T-cell growth factor. Proc Natl Acad Sci U S A. 1983 Nov; 80(22):6957-61.
Leonard WJ, Depper JM, Robb RJ, Waldmann TA, Greene WC. PMID: 6417659; PMCID: PMC390105.
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55 Fields:
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Association of human T-cell leukaemia/lymphoma virus with the Tac antigen marker for the human T-cell growth factor receptor. Nature. 1983 Oct 20-26; 305(5936):733-6.
Lando Z, Sarin P, Megson M, Greene WC, Waldman TA, Gallo RC, Broder S. PMID: 6195529.
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26 Fields:
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Direct demonstration of the identity of T cell growth factor binding protein and the Tac antigen. J Exp Med. 1983 Oct 01; 158(4):1332-7.
Robb RJ, Greene WC. PMID: 6413637; PMCID: PMC2187370.
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43 Fields:
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Blockade of the interleukin-2 receptor by anti-Tac antibody: inhibition of human lymphocyte activation. J Immunol. 1983 Aug; 131(2):690-6.
Depper JM, Leonard WJ, Robb RJ, Waldmann TA, Greene WC. PMID: 6408186.
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56 Fields:
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Rearrangement and expression of immunoglobulin genes and expression of Tac antigen in hairy cell leukemia. Proc Natl Acad Sci U S A. 1983 Jul; 80(14):4522-6.
Korsmeyer SJ, Greene WC, Cossman J, Hsu SM, Jensen JP, Neckers LM, Marshall SL, Bakhshi A, Depper JM, Leonard WJ, Jaffe ES, Waldmann TA. PMID: 6192435; PMCID: PMC384071.
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50 Fields:
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Evidence for an interleukin-independent pathway for human lymphocyte activation. Proc Natl Acad Sci U S A. 1983 Jun; 80(11):3444-7.
Koretzky GA, Daniele RP, Greene WC, Nowell PC. PMID: 6407014; PMCID: PMC394060.
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16 Fields:
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HumansCells
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Polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen. J Exp Med. 1983 Mar 01; 157(3):1064-9.
Cossman J, Neckers LM, Leonard WJ, Greene WC. PMID: 6220104; PMCID: PMC2186955.
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25 Fields:
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HumansAnimalsCells
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Construction of human suppressor T cell hybridomas. Lymphokine Res. 1983; 2(2):53-60.
Greene WC, Depper JM, Leonard WJ, Fleisher TA, Waldmann TA. PMID: 6236341.
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HumansCells
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The role of cell surface lectin--carbohydrate interactions in cellular recognition, cooperation, and regulation. Am J Pediatr Hematol Oncol. 1983; 5(2):199-206.
Blaese RM, Tosato G, Greene WC, Fleisher TA, Muchmore AV. PMID: 6193722.
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1 Fields:
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HumansAnimalsCells
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In: Golde DW, Marks PA (Eds.), Normal and Neoplastic Hematopoiesis, UCLA Symposia on Molecular and Cellular Biology. Hairy cell leukemia: A malignant expansion of B cells that express Tac antigen. 1983; 9:491-500.
Greene WC, Cossman J, Leonard WJ, Bakshi A, Waldmann TA, Korsmeyer SJ.
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A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor. Nature. 1982 Nov 18; 300(5889):267-9.
Leonard WJ, Depper JM, Uchiyama T, Smith KA, Waldmann TA, Greene WC. PMID: 6815536.
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209 Fields:
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Humans
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Production of human suppressor T cell hybridomas. J Immunol. 1982 Nov; 129(5):1986-92.
Greene WC, Fleisher TA, Nelson DL, Waldmann TA. PMID: 6214585.
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2 Fields:
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HumansCells
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Interferon-mediated inhibition of human polyclonal immunoglobulin synthesis. J Immunol. 1982 Sep; 129(3):1099-103.
Fleisher TA, Attallah AM, Tosato G, Blaese RM, Greene WC. PMID: 6179992.
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5 Fields:
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HumansCells
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Characterization of a soluble suppressor of human B cell function produced by a continuous human suppressor T cell line. II. Evidence for suppression through a direct action of CTC-SISS-B on human B cells. J Immunol. 1982 Sep; 129(3):1120-3.
Greene WC, Fleisher TA, Depper JM, Leonard WJ, Stanton GJ, Waldmann TA. PMID: 6213708.
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2 Fields:
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HumansCells
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In: Oppenheim JJ, Cohen S (Eds.), Interleukins, lymphokines, and cytokines. Monoclonal anti-Tac blocks the action of human interleukin-2. 1982; 19-24.
Depper JM, Leonard WJ, Smith KA, Waldmann TA, Greene WC.
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Stimulation of immunoglobulin biosynthesis in human B cells by wheat germ agglutinin. I. Evidence that WGA can produce both a positive and negative signal for activation of human lymphocytes. J Immunol. 1981 Aug; 127(2):799-804.
Greene WC, Goldman CK, Marshall ST, Fleisher TA, Waldmann TA. PMID: 6265558.
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1 Fields:
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HumansCells
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Characterization of a soluble suppressor of human B cell immunoglobulin biosynthesis produced by a continuous human suppressor T cell line. J Exp Med. 1981 Jul 01; 154(1):156-67.
Fleisher TA, Greene WC, Uchiyama T, Goldman CK, Nelson DL, Blaese RM, Waldmann TA. PMID: 6454754; PMCID: PMC2186401.
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4 Fields:
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HumansAnimalsCells
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Soluble suppressor supernatants elaborated by concanavalin A-activated human mononuclear cells. II. Characterization of a soluble suppressor of B cell immunoglobulin production. J Immunol. 1981 Mar; 126(3):1192-7.
Fleisher TA, Greene WC, Blaese RM, Waldmann TA. PMID: 6450804.
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9 Fields:
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HumansCells
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Soluble suppressor supernatants elaborated by concanavalin A-activated human mononuclear cells. I. Characterization of a soluble suppressor T cell proliferation. J Immunol. 1981 Mar; 126(3):1185-91.
Greene WC, Fleisher TA, Waldmann TA. PMID: 6450803.
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26 Fields:
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HumansAnimalsCells
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Suppression of human T and B lymphocyte activation by Agaricus bisporus lectin. I. Suggestive evidence for a surface "suppressor" receptor in human lymphocytes. J Immunol. 1981 Feb; 126(2):580-6.
Greene WC, Fleisher TA, Waldmann TA. PMID: 6778919.
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3 Fields:
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HumansAnimalsCells
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Inhibition of human lymphocyte proliferation by the nonmitogenic lectin wheat germ agglutinin. J Immunol. 1980 Jun; 124(6):2979-87.
Greene WC, Waldmann TA. PMID: 6966300.
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8 Fields:
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HumansAnimalsCells
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In: Cramer H, Schultz J (Eds.), Mechanism of Action. Cyclic nucleotides in the immune response. 1977; 161-187.
Parker CW, Greene WC.
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Cytochalasin binding in lymphocytes and polymorphonuclear leukocytes. Exp Cell Res. 1976 Nov; 103(1):99-108.
Parker CW, Greene WC, MacDonald HH. PMID: 991953.
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6 Fields:
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Cells
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Cytochalasin sensitive structures and lymphocyte activation. Exp Cell Res. 1976 Nov; 103(1):109-17.
Greene WC, Parker CM, Parker CW. PMID: 186286.
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3 Fields:
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Cells
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Colchicine-sensitive structures and lymphocyte activation. J Immunol. 1976 Sep; 117(3):1015-22.
Greene WC, Parker CM, Parker CW. PMID: 956646.
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11 Fields:
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HumansCells
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Opposing effects of mitogenic and nonmitogenic lectins on lymphocyte activation. Evidence that wheat germ agglutinin produces a negative signal. J Biol Chem. 1976 Jul 10; 251(13):4017-25.
Greene WC, Parker CM, Parker CW. PMID: 932019.
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12 Fields:
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HumansAnimalsCells
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Calcium and lymphocyte activation. Cell Immunol. 1976 Jul; 25(1):74-89.
Greene WC, Parker CM, Parker CW. PMID: 183895.
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12 Fields:
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HumansAnimals
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Studies on the stimulation of cAMP metabolism in human lymphocytes by latex polymers. Exp Cell Res. 1976 May; 99(2):395-407.
Atkinson JP, Greene WC, McNearney TA, Parker CW. PMID: 178514.
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3 Fields:
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HumansAnimalsCells
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In: Eijsvoogel W, Roos D, Zeijlemaker WP (Eds.), Leukocyte membrane determinants regulating immune reactivity. Calcium ionophore A23187 and lymphocyte activation. 1976; 10:129.
Greene WC, Wedner HJ, Parker CW.
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Suggestive evidence for both stimulatory and inhibitory domains on human lymphocytes, as indicated by phospholipid turnover studies with wheat germ agglutinin and other lectins. Immunol Commun. 1976; 5(1-2):13-25.
Parker CW, Dankner RE, Falkenhein SF, Greene WC. PMID: 181319.
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4 Fields:
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HumansAnimalsCells
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A role for cytochalasin-sensitive proteins in the regulation of calcium transport in activated human lymphocytes. Biochem Biophys Res Commun. 1975 Jul 22; 65(2):456-63.
Greene WC, Parker CW. PMID: 167774.
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HumansCells
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Concanavalin A-induced histamine release from normal rat mast cells. J Immunol. 1975 Jul; 115(1):278-82.
Sullivan TJ, Greene WC, Parker CW. PMID: 50352.
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21 Fields:
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AnimalsCells
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Effect of experimental diabetes mellitus on kidney ribosomal protein synthesis. Diabetes. 1971 Oct; 20(10):649-54.
Peterson DT, Greene WC, Reaven GM. PMID: 5110696.
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13 Fields:
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AnimalsCells