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    Vivek Jain, MD

    TitleAssistant Professor
    SchoolUCSF School of Medicine
    DepartmentMedicine
    AddressSFGH HIV/AIDS Div., Ward 84
    San Francisco CA 94143
    Phone415-476-4082x355

       Overview 
       Overview
      Vivek Jain, M.D., M.A.S. is an assistant professor of medicine and infectious diseases in the HIV/AIDS Division at San Francisco General Hospital, UCSF. He conducts implementation science research on HIV antiretroviral therapy (ART) delivery in resource limited settings, working within collaborations between UCSF and collaborators in Uganda and Kenya. The goal of this research is to develop, test and understand the most optimal ways in which earlier ART can be delivered to affected populations in Sub Saharan Africa. He is also conducting clinical translational research on the immunologic and virologic impact of early versus deferred initiation of HIV antiretroviral therapy. The goal of this research is to better define the optimal time for ART initiation, and to explore and understand the biology of early HIV infection and what impact early-initiated ART exerts on it.

      Dr. Jain earned his undergraduate degree in Biochemistry from Harvard University, followed by his M.D. from Stanford University School of Medicine. He completed residency, chief residency, and infectious disease fellowship at UCSF, as well as an M.A.S. degree in clinical research also at UCSF. Dr. Jain serves as an outpatient HIV physician in the Positive Health Practice Clinic at San Francisco General Hospital, and an attending physician on the inpatient infectious disease consult team.

       Interests
      HIV and infectious disease medicine, HIV antiretroviral therapy (ART), HIV therapeutic strategies, ART delivery, early ART, implementation science, resource limited settings, Sub Saharan Africa, acute/early HIV disease, HIV immunology and virology, HIV drug resistance, clinical trials, clinical cohorts.

       ORNG Applications 
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       In The News
       Global Health

       Bibliographic 
       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Jain V, Byonanebye DM, Liegler T, Kwarisiima D, Chamie G, Kabami J, Petersen ML, Balzer LB, Clark TD, Black D, Thirumurthy H, Geng EH, Charlebois ED, Amanyire G, Kamya MR, Havlir DV. Changes in Population HIV RNA Levels in Mbarara, Uganda, During Scale-up of HIV Antiretroviral Therapy Access. J Acquir Immune Defic Syndr. 2014 Mar 1; 65(3):327-32.
        View in: PubMed
      2. Kotwani P, Balzer L, Kwarisiima D, Clark TD, Kabami J, Byonanebye D, Bainomujuni B, Black D, Chamie G, Jain V, Thirumurthy H, Kamya MR, Geng EH, Petersen ML, Havlir DV, Charlebois ED. Evaluating linkage to care for hypertension after community-based screening in rural Uganda. Trop Med Int Health. 2014 Feb 3.
        View in: PubMed
      3. Chamie G, Kwarisiima D, Clark TD, Kabami J, Jain V, Geng E, Balzer LB, Petersen ML, Thirumurthy H, Charlebois ED, Kamya MR, Havlir DV. Uptake of Community-Based HIV Testing during a Multi-Disease Health Campaign in Rural Uganda. PLoS One. 2014; 9(1):e84317.
        View in: PubMed
      4. Kotwani P, Kwarisiima D, Clark TD, Kabami J, Geng EH, Jain V, Chamie G, Petersen ML, Thirumurthy H, Kamya MR, Charlebois ED, Havlir DV. Epidemiology and awareness of hypertension in a rural Ugandan community: a cross-sectional study. BMC Public Health. 2013; 13(1):1151.
        View in: PubMed
      5. Namusobya J, Semitala FC, Amanyire G, Kabami J, Chamie G, Bogere J, Jain V, Clark TD, Charlebois E, Havlir DV, Kamya M, Geng EH. High retention in care among HIV-infected patients entering care with CD4 levels >350 cells/µL under routine program conditions in Uganda. Clin Infect Dis. 2013 Nov; 57(9):1343-50.
        View in: PubMed
      6. Jain V, Hartogensis W, Bacchetti P, Hunt PW, Hatano H, Sinclair E, Epling L, Lee TH, Busch MP, McCune JM, Pilcher CD, Hecht FM, Deeks SG. Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size. J Infect Dis. 2013 Oct 15; 208(8):1202-11.
        View in: PubMed
      7. Thirumurthy H, Chamie G, Jain V, Kabami J, Kwarisiima D, Clark TD, Geng E, Petersen ML, Charlebois ED, Kamya MR, Havlir DV. Improved employment and education outcomes in households of HIV-infected adults with high CD4 cell counts: evidence from a community health campaign in Uganda. AIDS. 2013 Feb 20; 27(4):627-34.
        View in: PubMed
      8. Jain V, Liegler T, Kabami J, Chamie G, Clark TD, Black D, Geng EH, Kwarisiima D, Wong JK, Abdel-Mohsen M, Sonawane N, Aweeka FT, Thirumurthy H, Petersen ML, Charlebois ED, Kamya MR, Havlir DV. Assessment of population-based HIV RNA levels in a rural east African setting using a fingerprick-based blood collection method. Clin Infect Dis. 2013 Feb; 56(4):598-605.
        View in: PubMed
      9. Hatano H, Jain V, Hunt PW, Lee TH, Sinclair E, Do TD, Hoh R, Martin JN, McCune JM, Hecht F, Busch MP, Deeks SG. Cell-based measures of viral persistence are associated with immune activation and programmed cell death protein 1 (PD-1)-expressing CD4+ T cells. J Infect Dis. 2013 Jul; 208(1):50-6.
        View in: PubMed
      10. Geng EH, Hare CB, Kahn JO, Jain V, Van Nunnery T, Christopoulos KA, Deeks SG, Gandhi M, Havlir DV. The effect of a "universal antiretroviral therapy" recommendation on HIV RNA levels among HIV-infected patients entering care with a CD4 count greater than 500/µL in a public health setting. Clin Infect Dis. 2012 Dec; 55(12):1690-7.
        View in: PubMed
      11. Chamie G, Kwarisiima D, Clark TD, Kabami J, Jain V, Geng E, Petersen ML, Thirumurthy H, Kamya MR, Havlir DV, Charlebois ED. Leveraging rapid community-based HIV testing campaigns for non-communicable diseases in rural Uganda. PLoS One. 2012; 7(8):e43400.
        View in: PubMed
      12. Jain V, Sucupira MC, Bacchetti P, Hartogensis W, Diaz RS, Kallas EG, Janini LM, Liegler T, Pilcher CD, Grant RM, Cortes R, Deeks SG, Hecht FM. Differential persistence of transmitted HIV-1 drug resistance mutation classes. J Infect Dis. 2011 Apr 15; 203(8):1174-81.
        View in: PubMed
      13. Jain V, Liegler T, Vittinghoff E, Hartogensis W, Bacchetti P, Poole L, Loeb L, Pilcher CD, Grant RM, Deeks SG, Hecht FM. Transmitted drug resistance in persons with acute/early HIV-1 in San Francisco, 2002-2009. PLoS One. 2010; 5(12):e15510.
        View in: PubMed
      14. Jain V, Deeks SG. When to start antiretroviral therapy. Curr HIV/AIDS Rep. 2010 May; 7(2):60-8.
        View in: PubMed
      15. Gayatri NA, Morrall MC, Jain V, Kashyape P, Pysden K, Ferrie C. Parental and physician beliefs regarding the provision and content of written sudden unexpected death in epilepsy (SUDEP) information. Epilepsia. 2010 May; 51(5):777-82.
        View in: PubMed
      16. Buchbinder SP, Jain V. Early versus deferred antiretroviral therapy for HIV. N Engl J Med. 2009 Aug 20; 361(8):822; author reply 823-4.
        View in: PubMed
      17. Jain V, Yang MH, Kovacicova-Lezcano G, Juhle LS, Bolger AF, Winston LG. Infective endocarditis in an urban medical center: association of individual drugs with valvular involvement. J Infect. 2008 Aug; 57(2):132-8.
        View in: PubMed
      18. Gentsch JR, Laird AR, Bielfelt B, Griffin DD, Banyai K, Ramachandran M, Jain V, Cunliffe NA, Nakagomi O, Kirkwood CD, Fischer TK, Parashar UD, Bresee JS, Jiang B, Glass RI. Serotype diversity and reassortment between human and animal rotavirus strains: implications for rotavirus vaccine programs. J Infect Dis. 2005 Sep 1; 192 Suppl 1:S146-59.
        View in: PubMed
      19. Clark HF, Lawley DA, Schaffer A, Patacsil JM, Marcello AE, Glass RI, Jain V, Gentsch J. Assessment of the epidemic potential of a new strain of rotavirus associated with the novel G9 serotype which caused an outbreak in the United States for the first time in the 1995-1996 season. J Clin Microbiol. 2004 Apr; 42(4):1434-8.
        View in: PubMed
      20. Jain V, Noponen R, Smith BM. Pediatric surgical emergencies in the setting of a natural disaster: Experiences from the 2001 earthquake in Gujarat, India. J Pediatr Surg. 2003 May; 38(5):663-7.
        View in: PubMed
      21. Davis S, Papadopoulos N, Aldrich TH, Maisonpierre PC, Huang T, Kovac L, Xu A, Leidich R, Radziejewska E, Rafique A, Goldberg J, Jain V, Bailey K, Karow M, Fandl J, Samuelsson SJ, Ioffe E, Rudge JS, Daly TJ, Radziejewski C, Yancopoulos GD. Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering. Nat Struct Biol. 2003 Jan; 10(1):38-44.
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      22. Jain V, Das BK, Bhan MK, Glass RI, Gentsch JR. Great diversity of group A rotavirus strains and high prevalence of mixed rotavirus infections in India. J Clin Microbiol. 2001 Oct; 39(10):3524-9.
        View in: PubMed
      23. Jain V, Parashar UD, Glass RI, Bhan MK. Epidemiology of rotavirus in India. Indian J Pediatr. 2001 Sep; 68(9):855-62.
        View in: PubMed
      24. Jain V, Mekalanos JJ. Use of lambda phage S and R gene products in an inducible lysis system for Vibrio cholerae- and Salmonella enterica serovar typhimurium-based DNA vaccine delivery systems. Infect Immun. 2000 Feb; 68(2):986-9.
        View in: PubMed
      25. Davis S, Aldrich TH, Jones PF, Acheson A, Compton DL, Jain V, Ryan TE, Bruno J, Radziejewski C, Maisonpierre PC, Yancopoulos GD. Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. Cell. 1996 Dec 27; 87(7):1161-9.
        View in: PubMed
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