Pratik Mukherjee, MD, PhD
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| Title | Associate Professor in Residence |
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| School | UCSF School of Medicine |
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| Department | Radiology and Biomedical Imaging |
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| Address | 185 Berry Street, Suite 350 San Francisco CA 94107
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| Phone | 415-514-8972 |
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| Email | pratik.mukherjee@ucsf.edu |
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Biography | International Symposium on High-field MR in Clinical Applications Conference, Bonn, Germany | 2012 | | Keynote Lecturer | | GE Healthcare | 2009 | | MR Thought Leader | | Hospital for Sick Children, Toronto, Canada | 2008 | | Derek Harwood-Nash Annual Lecture in Neuroradiology | | American Society of Neuroradiology | 2006 | | Outstanding Presentation Award in Functional Neuroradiology | | American Society of Neuroradiology | 2005 | | Berlex Best Paper Award in General Neuroradiology | | Neuroradiology Education and Research Foundation | 2004 | | Scholar Award in Neuroradiology Research | | American Society of Neuroradiology | 2001 | | Berlex/ASNR Award in Basic Science Research | | Radiological Society of North America | 1999 | | Roentgen Resident/Fellow Research Award | | Rockefeler University | 1994 | | S. Koide Memorial Fellowship | | Radiological Society of North America | 1989 | | Roentgen Resident/Fellow Research Award | | National Institutes of Health | 1988
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| 1995 | Medical Scientist Training Program |
Overview Pratik Mukherjee, MD, PhD, is an Associate Professor of Radiology and Biomedical Imaging, Bioengineering, and he is an attending neuroradiologist at the University of California, San Francisco. Dr. Mukherjee received his PhD in Neuroscience from Rockefeller University, New York. He obtained his medical degree in Medicine from Cornell University, New York, in 1995, and completed his residency in Radiology at New York Hospital Cornell Medical Center, followed by a fellowship in Neuroradiology from Washington University Medical Center in St. Louis, Missouri, in 2002.
Dr. Mukherjee’s primary clinical research is the study of traumatic brain injury (TBI) using advanced MRI imaging. His research has been focused on technical development, neuroscience and clinical applications of advanced imaging methods for mapping structure and function of the human brain. Mainly in diffusion tensor imaging (DTI), which is a popular technique for assessing the development and integrity of white matter, and for mapping axonal fiber pathways.
Dr. Mukherjee has served as Principal Investigator or Co-Principal Investigator for several NIH grants. He has 68 published articles and 5 book chapters. He has 5 significant publications where he had the responsibilities of senior and corresponding author of these studies, which he wrote, revised, and finalized these manuscripts.
Expertise: Radiology, Neuroradiology, Pediatric Neuroradiology, Cognitive Neuroscience
Specialty: Neuroradiology, traumatic brain injury (TBI)
Professional Interests: Brain development, computational neuroscience, connectomics, diffusion tensor imaging (DTI), epilepsy, functional MRI (fMRI), machine learning, magnetoencephalography (MEG), pediatric neuroradiology, traumatic brain injury (TBI), ultra-high field MRI, white matter tractography
Education and Training: • Medical School: Cornell University, New York - Medicine • Internship: New York Cornell Medical Center - Internal Medicine • Residency: Washington University of Medical Center, St. Louis, Missouri - Radiology • Fellowship: Washington University Medical Center, St. Louis, Missouri - Neuroradiology • Doctor of Philosophy: Rockefeller University, New York - Neuroscience • National Board of Medical Examiners Certificate #416732 • American Board of Radiology Certificate #46843 • Missouri Medical License #2000160532 • California Medical License #G86473 • American Board of Radiology Certificate of Added Qualification Neuroradiology #46844
Brain development, computational neuroscience, connectomics, diffusion tensor imaging (DTI), epilepsy, functional MRI (fMRI), machine learning, magnetoencephalography (MEG), pediatric neuroradiology, traumatic brain injury (TBI), ultra-high field MRI, white matter tractography.
Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Tarapore PE, Findlay AM, Lahue SC, Lee H, Honma SM, Mizuiri D, Luks TL, Manley GT, Nagarajan SS, Mukherjee P. Resting state magnetoencephalography functional connectivity in traumatic brain injury. J Neurosurg. 2013 Jun; 118(6):1306-16.
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Xu D, Mukherjee P, Barkovich AJ. Pediatric brain injury: can DTI scalars predict functional outcome? Pediatr Radiol. 2013 Jan; 43(1):55-9.
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Owen JP, Ziv E, Bukshpun P, Pojman N, Wakahiro M, Berman JI, Roberts TP, Friedman EJ, Sherr EH, Mukherjee P. Test-retest reliability of computational network measurements derived from the structural connectome of the human brain. Brain Connect. 2013; 3(2):160-76.
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Owen JP, Li YO, Ziv E, Strominger Z, Gold J, Bukhpun P, Wakahiro M, Friedman EJ, Sherr EH, Mukherjee P. The structural connectome of the human brain in agenesis of the corpus callosum. Neuroimage. 2013 Apr 15; 70:340-55.
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Yuh EL, Mukherjee P, Lingsma HF, Yue JK, Ferguson AR, Gordon WA, Valadka AB, Schnyer DM, Okonkwo DO, Maas AI, Manley GT. Magnetic resonance imaging improves 3-month outcome prediction in mild traumatic brain injury. Ann Neurol. 2013 Feb; 73(2):224-35.
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Zufferey F, Sherr EH, Beckmann ND, Hanson E, Maillard AM, Hippolyte L, Macé A, Ferrari C, Kutalik Z, Andrieux J, Aylward E, Barker M, Bernier R, Bouquillon S, Conus P, Delobel B, Faucett WA, Goin-Kochel RP, Grant E, Harewood L, Hunter JV, Lebon S, Ledbetter DH, Martin CL, Männik K, Martinet D, Mukherjee P, Ramocki MB, Spence SJ, Steinman KJ, Tjernagel J, Spiro JE, Reymond A, Beckmann JS, Chung WK, Jacquemont S. A 600 kb deletion syndrome at 16p11.2 leads to energy imbalance and neuropsychiatric disorders. J Med Genet. 2012 Oct; 49(10):660-8.
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Hinkley LB, Marco EJ, Findlay AM, Honma S, Jeremy RJ, Strominger Z, Bukshpun P, Wakahiro M, Brown WS, Paul LK, Barkovich AJ, Mukherjee P, Nagarajan SS, Sherr EH. The role of corpus callosum development in functional connectivity and cognitive processing. PLoS One. 2012; 7(8):e39804.
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Li YO, Yang FG, Nguyen CT, Cooper SR, LaHue SC, Venugopal S, Mukherjee P. Independent component analysis of DTI reveals multivariate microstructural correlations of white matter in the human brain. Hum Brain Mapp. 2012 Jun; 33(6):1431-51.
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Hess CP, Mukherjee P, Barbaro NM. Epileptic foci. J Neurosurg. 2011 Jun; 114(6):1691-2; discussion 1692.
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Duhaime AC, Gean AD, Haacke EM, Hicks R, Wintermark M, Mukherjee P, Brody D, Latour L, Riedy G. Common data elements in radiologic imaging of traumatic brain injury. Arch Phys Med Rehabil. 2010 Nov; 91(11):1661-6.
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Haacke EM, Duhaime AC, Gean AD, Riedy G, Wintermark M, Mukherjee P, Brody DL, DeGraba T, Duncan TD, Elovic E, Hurley R, Latour L, Smirniotopoulos JG, Smith DH. Common data elements in radiologic imaging of traumatic brain injury. J Magn Reson Imaging. 2010 Sep; 32(3):516-43.
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Wahl M, Strominger ZA, Wakahiro M, Jeremy RJ, Mukherjee P, Sherr EH. Diffusion tensor imaging of Aicardi syndrome. Pediatr Neurol. 2010 Aug; 43(2):87-91.
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Raj A, Hess C, Mukherjee P. Spatial HARDI: improved visualization of complex white matter architecture with Bayesian spatial regularization. Neuroimage. 2011 Jan 1; 54(1):396-409.
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Niogi SN, Mukherjee P. Diffusion tensor imaging of mild traumatic brain injury. J Head Trauma Rehabil. 2010 Jul-Aug; 25(4):241-55.
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Maruta J, Suh M, Niogi SN, Mukherjee P, Ghajar J. Visual tracking synchronization as a metric for concussion screening. J Head Trauma Rehabil. 2010 Jul-Aug; 25(4):293-305.
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Wahl M, Li YO, Ng J, Lahue SC, Cooper SR, Sherr EH, Mukherjee P. Microstructural correlations of white matter tracts in the human brain. Neuroimage. 2010 Jun; 51(2):531-41.
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Niogi S, Mukherjee P, Ghajar J, McCandliss BD. Individual Differences in Distinct Components of Attention are Linked to Anatomical Variations in Distinct White Matter Tracts. Front Neuroanat. 2010; 4:2.
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Wahl M, Barkovich AJ, Mukherjee P. Diffusion imaging and tractography of congenital brain malformations. Pediatr Radiol. 2010 Jan; 40(1):59-67.
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Wahl M, Mukherjee P. Diffusion imaging of congenital brain malformations. Semin Pediatr Neurol. 2009 Sep; 16(3):111-9.
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Reeder SB, Mukherjee P. Clinical applications of MR diffusion and perfusion imaging: Preface. Magn Reson Imaging Clin N Am. 2009 May; 17(2):xi-xii.
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Metcalf M, Xu D, Okuda DT, Carvajal L, Srinivasan R, Kelley DA, Mukherjee P, Nelson SJ, Vigneron DB, Pelletier D. High-resolution phased-array MRI of the human brain at 7 tesla: initial experience in multiple sclerosis patients. J Neuroimaging. 2010 Apr; 20(2):141-7.
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Van Boven RW, Harrington GS, Hackney DB, Ebel A, Gauger G, Bremner JD, D'Esposito M, Detre JA, Haacke EM, Jack CR, Jagust WJ, Le Bihan D, Mathis CA, Mueller S, Mukherjee P, Schuff N, Chen A, Weiner MW. Advances in neuroimaging of traumatic brain injury and posttraumatic stress disorder. J Rehabil Res Dev. 2009; 46(6):717-57.
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Niogi SN, Mukherjee P, Ghajar J, Johnson CE, Kolster R, Lee H, Suh M, Zimmerman RD, Manley GT, McCandliss BD. Structural dissociation of attentional control and memory in adults with and without mild traumatic brain injury. Brain. 2008 Dec; 131(Pt 12):3209-21.
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Lee H, Wintermark M, Gean AD, Ghajar J, Manley GT, Mukherjee P. Focal lesions in acute mild traumatic brain injury and neurocognitive outcome: CT versus 3T MRI. J Neurotrauma. 2008 Sep; 25(9):1049-56.
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von Morze C, Purcell DD, Banerjee S, Xu D, Mukherjee P, Kelley DA, Majumdar S, Vigneron DB. High-resolution intracranial MRA at 7T using autocalibrating parallel imaging: initial experience in vascular disease patients. Magn Reson Imaging. 2008 Dec; 26(10):1329-33.
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Xu D, Cunningham CH, Chen AP, Li Y, Kelley DA, Mukherjee P, Pauly JM, Nelson SJ, Vigneron DB. Phased array 3D MR spectroscopic imaging of the brain at 7 T. Magn Reson Imaging. 2008 Nov; 26(9):1201-6.
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Mukherjee P, Berman JI, Chung SW, Hess CP, Henry RG. Diffusion tensor MR imaging and fiber tractography: theoretic underpinnings. AJNR Am J Neuroradiol. 2008 Apr; 29(4):632-41.
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Mukherjee P, Chung SW, Berman JI, Hess CP, Henry RG. Diffusion tensor MR imaging and fiber tractography: technical considerations. AJNR Am J Neuroradiol. 2008 May; 29(5):843-52.
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Rodriguez-Carranza CE, Mukherjee P, Vigneron D, Barkovich J, Studholme C. A framework for in vivo quantification of regional brain folding in premature neonates. Neuroimage. 2008 Jun; 41(2):462-78.
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Wang ZJ, Vigneron DB, Miller SP, Mukherjee P, Charlton NN, Lu Y, Barkovich AJ. Brain metabolite levels assessed by lactate-edited MR spectroscopy in premature neonates with and without pentobarbital sedation. AJNR Am J Neuroradiol. 2008 Apr; 29(4):798-801.
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Hammond KE, Lupo JM, Xu D, Metcalf M, Kelley DA, Pelletier D, Chang SM, Mukherjee P, Vigneron DB, Nelson SJ. Development of a robust method for generating 7.0 T multichannel phase images of the brain with application to normal volunteers and patients with neurological diseases. Neuroimage. 2008 Feb 15; 39(4):1682-92.
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Hess CP, Mukherjee P. Visualizing white matter pathways in the living human brain: diffusion tensor imaging and beyond. Neuroimaging Clin N Am. 2007 Nov; 17(4):407-26, vii.
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von Morze C, Xu D, Purcell DD, Hess CP, Mukherjee P, Saloner D, Kelley DA, Vigneron DB. Intracranial time-of-flight MR angiography at 7T with comparison to 3T. J Magn Reson Imaging. 2007 Oct; 26(4):900-4.
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Berman JI, Chung S, Mukherjee P, Hess CP, Han ET, Henry RG. Probabilistic streamline q-ball tractography using the residual bootstrap. Neuroimage. 2008 Jan 1; 39(1):215-22.
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Li J, Shivakumar S, Wakahiro M, Mukherjee P, Barkovich AJ, Slavotinek A, Sherr EH. Agenesis of the corpus callosum, optic coloboma, intractable seizures, craniofacial and skeletal dysmorphisms: an autosomal recessive disorder similar to Temtamy syndrome. Am J Med Genet A. 2007 Aug 15; 143A(16):1900-5.
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Mukherjee P, Hess CP, Xu D, Han ET, Kelley DA, Vigneron DB. Development and initial evaluation of 7-T q-ball imaging of the human brain. Magn Reson Imaging. 2008 Feb; 26(2):171-80.
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Paul LK, Brown WS, Adolphs R, Tyszka JM, Richards LJ, Mukherjee P, Sherr EH. Agenesis of the corpus callosum: genetic, developmental and functional aspects of connectivity. Nat Rev Neurosci. 2007 Apr; 8(4):287-99.
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Niogi SN, Mukherjee P, McCandliss BD. Diffusion tensor imaging segmentation of white matter structures using a Reproducible Objective Quantification Scheme (ROQS). Neuroimage. 2007 Mar; 35(1):166-74.
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Chen JS, Mukherjee P, Dillon WP, Wintermark M. Restricted diffusion in bilateral optic nerves and retinas as an indicator of venous ischemia caused by cavernous sinus thrombophlebitis. AJNR Am J Neuroradiol. 2006 Oct; 27(9):1815-6.
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Hess CP, Mukherjee P, Han ET, Xu D, Vigneron DB. Q-ball reconstruction of multimodal fiber orientations using the spherical harmonic basis. Magn Reson Med. 2006 Jul; 56(1):104-17.
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Partridge SC, Vigneron DB, Charlton NN, Berman JI, Henry RG, Mukherjee P, McQuillen PS, Karl TR, Barkovich AJ, Miller SP. Pyramidal tract maturation after brain injury in newborns with heart disease. Ann Neurol. 2006 Apr; 59(4):640-51.
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Barkovich AJ, Miller SP, Bartha A, Newton N, Hamrick SE, Mukherjee P, Glenn OA, Xu D, Partridge JC, Ferriero DM, Vigneron DB. MR imaging, MR spectroscopy, and diffusion tensor imaging of sequential studies in neonates with encephalopathy. AJNR Am J Neuroradiol. 2006 Mar; 27(3):533-47.
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Mukherjee P, McKinstry RC. Diffusion tensor imaging and tractography of human brain development. Neuroimaging Clin N Am. 2006 Feb; 16(1):19-43, vii.
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Rodriguez-Carranza C, Mukherjee P, Vigneron D, Barkovich J, Studholme C. A system for measuring regional surface folding of the neonatal brain from MRI. Med Image Comput Comput Assist Interv. 2006; 9(Pt 2):201-8.
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Miller SP, Ferriero DM, Leonard C, Piecuch R, Glidden DV, Partridge JC, Perez M, Mukherjee P, Vigneron DB, Barkovich AJ. Early brain injury in premature newborns detected with magnetic resonance imaging is associated with adverse early neurodevelopmental outcome. J Pediatr. 2005 Nov; 147(5):609-16.
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Berman JI, Mukherjee P, Partridge SC, Miller SP, Ferriero DM, Barkovich AJ, Vigneron DB, Henry RG. Quantitative diffusion tensor MRI fiber tractography of sensorimotor white matter development in premature infants. Neuroimage. 2005 Oct 1; 27(4):862-71.
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Partridge SC, Mukherjee P, Berman JI, Henry RG, Miller SP, Lu Y, Glenn OA, Ferriero DM, Barkovich AJ, Vigneron DB. Tractography-based quantitation of diffusion tensor imaging parameters in white matter tracts of preterm newborns. J Magn Reson Imaging. 2005 Oct; 22(4):467-74.
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Deipolyi AR, Mukherjee P, Gill K, Henry RG, Partridge SC, Veeraraghavan S, Jin H, Lu Y, Miller SP, Ferriero DM, Vigneron DB, Barkovich AJ. Comparing microstructural and macrostructural development of the cerebral cortex in premature newborns: diffusion tensor imaging versus cortical gyration. Neuroimage. 2005 Sep; 27(3):579-86.
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Mukherjee P. Diffusion tensor imaging and fiber tractography in acute stroke. Neuroimaging Clin N Am. 2005 Aug; 15(3):655-65, xii.
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Le TH, Mukherjee P, Henry RG, Berman JI, Ware M, Manley GT. Diffusion tensor imaging with three-dimensional fiber tractography of traumatic axonal shearing injury: an imaging correlate for the posterior callosal "disconnection" syndrome: case report. Neurosurgery. 2005; 56(1):189.
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Ojemann JG, McKinstry RC, Mukherjee P, Park TS, Burton H. Hand somatosensory cortex activity following selective dorsal rhizotomy: report of three cases with fMRI. Childs Nerv Syst. 2005 Feb; 21(2):115-21.
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Maas LC, Mukherjee P, Carballido-Gamio J, Veeraraghavan S, Miller SP, Partridge SC, Henry RG, Barkovich AJ, Vigneron DB. Early laminar organization of the human cerebrum demonstrated with diffusion tensor imaging in extremely premature infants. Neuroimage. 2004 Jul; 22(3):1134-40.
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Partridge SC, Mukherjee P, Henry RG, Miller SP, Berman JI, Jin H, Lu Y, Glenn OA, Ferriero DM, Barkovich AJ, Vigneron DB. Diffusion tensor imaging: serial quantitation of white matter tract maturity in premature newborns. Neuroimage. 2004 Jul; 22(3):1302-14.
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Xu D, Henry RG, Mukherjee P, Carvajal L, Miller SP, Barkovich AJ, Vigneron DB. Single-shot fast spin-echo diffusion tensor imaging of the brain and spine with head and phased array coils at 1.5 T and 3.0 T. Magn Reson Imaging. 2004 Jul; 22(6):751-9.
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Berman JI, Berger MS, Mukherjee P, Henry RG. Diffusion-tensor imaging-guided tracking of fibers of the pyramidal tract combined with intraoperative cortical stimulation mapping in patients with gliomas. J Neurosurg. 2004 Jul; 101(1):66-72.
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Wintermark M, Fischbein NJ, Mukherjee P, Yuh EL, Dillon WP. Unilateral putaminal CT, MR, and diffusion abnormalities secondary to nonketotic hyperglycemia in the setting of acute neurologic symptoms mimicking stroke. AJNR Am J Neuroradiol. 2004 Jun-Jul; 25(6):975-6.
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Nakamura K, Mukherjee P, Swanson RA. Vitamin B12 deficiency. Arch Neurol. 2004 Jun; 61(6):960.
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Henry RG, Berman JI, Nagarajan SS, Mukherjee P, Berger MS. Subcortical pathways serving cortical language sites: initial experience with diffusion tensor imaging fiber tracking combined with intraoperative language mapping. Neuroimage. 2004 Feb; 21(2):616-22.
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Mazumdar A, Mukherjee P, Miller JH, Malde H, McKinstry RC. Diffusion-weighted imaging of acute corticospinal tract injury preceding Wallerian degeneration in the maturing human brain. AJNR Am J Neuroradiol. 2003 Jun-Jul; 24(6):1057-66.
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Mukherjee P, Kang HC, Videen TO, McKinstry RC, Powers WJ, Derdeyn CP. Measurement of cerebral blood flow in chronic carotid occlusive disease: comparison of dynamic susceptibility contrast perfusion MR imaging with positron emission tomography. AJNR Am J Neuroradiol. 2003 May; 24(5):862-71.
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Miller JH, McKinstry RC, Philip JV, Mukherjee P, Neil JJ. Diffusion-tensor MR imaging of normal brain maturation: a guide to structural development and myelination. AJR Am J Roentgenol. 2003 Mar; 180(3):851-9.
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Neil J, Miller J, Mukherjee P, Hüppi PS. Diffusion tensor imaging of normal and injured developing human brain - a technical review. NMR Biomed. 2002 Nov-Dec; 15(7-8):543-52.
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Mukherjee P, Miller JH, Shimony JS, Philip JV, Nehra D, Snyder AZ, Conturo TE, Neil JJ, McKinstry RC. Diffusion-tensor MR imaging of gray and white matter development during normal human brain maturation. AJNR Am J Neuroradiol. 2002 Oct; 23(9):1445-56.
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Mukherjee P, Miller JH, Shimony JS, Conturo TE, Lee BC, Almli CR, McKinstry RC. Normal brain maturation during childhood: developmental trends characterized with diffusion-tensor MR imaging. Radiology. 2001 Nov; 221(2):349-58.
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Gauvain KM, McKinstry RC, Mukherjee P, Perry A, Neil JJ, Kaufman BA, Hayashi RJ. Evaluating pediatric brain tumor cellularity with diffusion-tensor imaging. AJR Am J Roentgenol. 2001 Aug; 177(2):449-54.
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Mukherjee P, McKinstry RC. Reversible posterior leukoencephalopathy syndrome: evaluation with diffusion-tensor MR imaging. Radiology. 2001 Jun; 219(3):756-65.
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Mukherjee P, Bahn MM, McKinstry RC, Shimony JS, Cull TS, Akbudak E, Snyder AZ, Conturo TE. Differences between gray matter and white matter water diffusion in stroke: diffusion-tensor MR imaging in 12 patients. Radiology. 2000 Apr; 215(1):211-20.
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Lee BC, Vo KD, Kido DK, Mukherjee P, Reichenbach J, Lin W, Yoon MS, Haacke M. MR high-resolution blood oxygenation level-dependent venography of occult (low-flow) vascular lesions. AJNR Am J Neuroradiol. 1999 Aug; 20(7):1239-42.
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Lin W, Mukherjee P, An H, Yu Y, Wang Y, Vo K, Lee B, Kido D, Haacke EM. Improving high-resolution MR bold venographic imaging using a T1 reducing contrast agent. J Magn Reson Imaging. 1999 Aug; 10(2):118-23.
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Mukherjee P, Kaplan E. The maintained discharge of neurons in the cat lateral geniculate nucleus: spectral analysis and computational modeling. Vis Neurosci. 1998 May-Jun; 15(3):529-39.
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Levine MW, Cleland BG, Mukherjee P, Kaplan E. Tailoring of variability in the lateral geniculate nucleus of the cat. Biol Cybern. 1996 Sep; 75(3):219-27.
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Mukherjee P, Kaplan E. Dynamics of neurons in the cat lateral geniculate nucleus: in vivo electrophysiology and computational modeling. J Neurophysiol. 1995 Sep; 74(3):1222-43.
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