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    Elizabeth Blackburn, PhD

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentBiochemistry and Biophysics
    Address600 16th Street
    San Francisco CA 94158
    Phone415-476-4912

       Biography 
       Awards and Honors
      2009Nobel Prize for Physiology or Medicine
      2009Paul Ehrlich and Ludwig Darmstaedter Prize

       Overview 
       Overview
      Dr. Elizabeth H. Blackburn, Morris Herztein Professor of Biology and Physiology in the Department of Biochemistry and Biophysics at the University of California, San Francisco, is a leader in the area of telomere and telomerase research.

      She discovered the molecular nature of telomeres - the ends of eukaryotic chromosomes that serve as protective caps essential for preserving the genetic information - and the ribonucleoprotein enzyme, telomerase. Blackburn and her research team at the University of California, San Francisco are working with various cells including human cells, with the goal of understanding telomerase and telomere biology.

      Blackburn earned her B.Sc. (1970) and M.Sc. (1972) degrees from the University of Melbourne in Australia, and her Ph.D. (1975) from the University of Cambridge in England. She did her postdoctoral work in Molecular and Cellular Biology from 1975 to 1977 at Yale.

      In 1978, Blackburn joined the faculty at the University of California at Berkeley in the Department of Molecular Biology. In 1990, she joined the Department of Microbiology and Immunology at UC San Francisco, where she served as Department Chair from 1993 to 1999. Blackburn is currently a faculty member in Department of Biochemistry and Biophysics at UCSF. She is also a Non-Resident Fellow of the Salk Institute.

      Throughout her career, Blackburn has been honored by her peers as the recipient of many prestigious awards. She was elected President of the American Society for Cell Biology for the year 1998. Blackburn is an elected Fellow of the American Academy of Arts and Sciences (1991), the Royal Society of London (1992), the American Academy of Microbiology (1993), and the American Association for the Advancement of Science (2000).

      She was elected Foreign Associate of the National Academy of Sciences in 1993, and was elected as a Member of the Institute of Medicine in 2000. She was awarded the Albert Lasker Medical Research Award in Basic Medical Research (2006). In 2007 she was named one of TIME Magazine’s 100 Most influential People and she is the 2008 North American Laureate for L’Oreal-UNESCO For Women in Science.


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       Bibliographic 
       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Chen SH, Epel ES, Mellon SH, Lin J, Reus VI, Rosser R, Kupferman E, Burke H, Mahan L, Blackburn EH, Wolkowitz OM. Adverse childhood experiences and leukocyte telomere maintenance in depressed and healthy adults. J Affect Disord. 2014 Dec 1; 169:86-90.
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      2. Jacobs EG, Epel ES, Lin J, Blackburn EH, Rasgon NL. Relationship between leukocyte telomere length, telomerase activity, and hippocampal volume in early aging. JAMA Neurol. 2014 Jul 1; 71(7):921-3.
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      3. Chen S, Yeh F, Lin J, Matsuguchi T, Blackburn E, Lee ET, Howard BV, Zhao J. Short leukocyte telomere length is associated with obesity in American Indians: The strong heart family study. Aging (Albany NY). 2014 May; 6(5):380-9.
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      4. Chen S, Lin J, Matsuguchi T, Blackburn E, Yeh F, Best LG, Devereux RB, Lee ET, Howard BV, Roman MJ, Zhao J. Short leukocyte telomere length predicts incidence and progression of carotid atherosclerosis in American Indians: The Strong Heart Family Study. Aging (Albany NY). 2014 May; 6(5):414-27.
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      5. Zalli A, Carvalho LA, Lin J, Hamer M, Erusalimsky JD, Blackburn EH, Steptoe A. Shorter telomeres with high telomerase activity are associated with raised allostatic load and impoverished psychosocial resources. Proc Natl Acad Sci U S A. 2014 Mar 25; 111(12):4519-24.
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      6. Zhao J, Zhu Y, Uppal K, Tran VT, Yu T, Lin J, Matsuguchi T, Blackburn E, Jones D, Lee ET, Howard BV. Metabolic profiles of biological aging in American Indians: The strong heart family study. Aging (Albany NY). 2014 Mar; 6(3):176-86.
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      7. Rehkopf DH, Dow WH, Rosero-Bixby L, Lin J, Epel ES, Blackburn EH. Seasonal variation of peripheral blood leukocyte telomere length in Costa Rica: A population-based observational study. Am J Hum Biol. 2014 May; 26(3):367-75.
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      8. Chae DH, Nuru-Jeter AM, Adler NE, Brody GH, Lin J, Blackburn EH, Epel ES. Discrimination, racial bias, and telomere length in african-american men. Am J Prev Med. 2014 Feb; 46(2):103-11.
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      9. Buss J, Havel PJ, Epel E, Lin J, Blackburn E, Daubenmier J. Associations of ghrelin with eating behaviors, stress, metabolic factors, and telomere length among overweight and obese women: Preliminary evidence of attenuated ghrelin effects in obesity? Appetite. 2014 May; 76:84-94.
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      10. Chen B, Gilbert LA, Cimini BA, Schnitzbauer J, Zhang W, Li GW, Park J, Blackburn EH, Weissman JS, Qi LS, Huang B. Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System. Cell. 2013 Dec 19; 155(7):1479-91.
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      11. Listerman I, Gazzaniga FS, Blackburn EH. An investigation of the effects of the core protein telomerase reverse transcriptase on wnt signaling in breast cancer cells. Mol Cell Biol. 2014 Jan; 34(2):280-9.
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      12. Ornish D, Lin J, Chan JM, Epel E, Kemp C, Weidner G, Marlin R, Frenda SJ, Magbanua MJ, Daubenmier J, Estay I, Hills NK, Chainani-Wu N, Carroll PR, Blackburn EH. Effect of comprehensive lifestyle changes on telomerase activity and telomere length in men with biopsy-proven low-risk prostate cancer: 5-year follow-up of a descriptive pilot study. Lancet Oncol. 2013 Oct; 14(11):1112-20.
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      13. Zhu Y, Voruganti VS, Lin J, Matsuguchi T, Blackburn E, Best LG, Lee ET, MacCluer JW, Cole SA, Zhao J. QTL mapping of leukocyte telomere length in American Indians: the Strong Heart Family Study. Aging (Albany NY). 2013 Sep; 5(9):704-16.
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      14. Rehkopf DH, Dow WH, Rosero-Bixby L, Lin J, Epel ES, Blackburn EH. Longer leukocyte telomere length in Costa Rica's Nicoya Peninsula: a population-based study. Exp Gerontol. 2013 Nov; 48(11):1266-73.
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      15. Zhao J, Zhu Y, Lin J, Matsuguchi T, Blackburn E, Zhang Y, Cole SA, Best LG, Lee ET, Howard BV. Short leukocyte telomere length predicts risk of diabetes in american indians: the strong heart family study. Diabetes. 2014 Jan; 63(1):354-62.
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      16. Puterman E, Epel ES, Lin J, Blackburn EH, Gross JJ, Whooley MA, Cohen BE. Multisystem resiliency moderates the major depression-telomere length association: findings from the Heart and Soul Study. Brain Behav Immun. 2013 Oct; 33:65-73.
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      17. Listerman I, Sun J, Gazzaniga FS, Lukas JL, Blackburn EH. The major reverse transcriptase-incompetent splice variant of the human telomerase protein inhibits telomerase activity but protects from apoptosis. Cancer Res. 2013 May 1; 73(9):2817-28.
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      18. Blackburn E, Chang J, Hücker M, Holmes AT, Christensen NB, Liang R, Bonn DA, Hardy WN, Rütt U, Gutowski O, von Zimmermann M, Forgan EM, Hayden SM. X-ray diffraction observations of a charge-density-wave order in superconducting ortho-II YBa2Cu3O6.54 single crystals in zero magnetic field. Phys Rev Lett. 2013 Mar 29; 110(13):137004.
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      19. Belin BJ, Cimini BA, Blackburn EH, Mullins RD. Visualization of actin filaments and monomers in somatic cell nuclei. Mol Biol Cell. 2013 Apr; 24(7):982-94.
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      20. Needham BL, Adler N, Gregorich S, Rehkopf D, Lin J, Blackburn EH, Epel ES. Socioeconomic status, health behavior, and leukocyte telomere length in the National Health and Nutrition Examination Survey, 1999-2002. Soc Sci Med. 2013 May; 85:1-8.
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      21. Jacobs EG, Kroenke C, Lin J, Epel ES, Kenna HA, Blackburn EH, Rasgon NL. Accelerated cell aging in female APOE-e4 carriers: implications for hormone therapy use. PLoS One. 2013; 8(2):e54713.
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      22. Dowd JB, Bosch JA, Steptoe A, Blackburn EH, Lin J, Rees-Clayton E, Aiello AE. Cytomegalovirus is associated with reduced telomerase activity in the Whitehall II cohort. Exp Gerontol. 2013 Apr; 48(4):385-90.
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      23. Entringer S, Epel ES, Lin J, Buss C, Shahbaba B, Blackburn EH, Simhan HN, Wadhwa PD. Maternal psychosocial stress during pregnancy is associated with newborn leukocyte telomere length. Am J Obstet Gynecol. 2013 Feb; 208(2):134.e1-7.
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      24. Bansal N, Whooley MA, Regan M, McCulloch CE, Ix JH, Epel E, Blackburn E, Lin J, Hsu CY. Association between kidney function and telomere length: the heart and soul study. Am J Nephrol. 2012; 36(5):405-11.
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      25. Blackburn EH, Epel ES. Telomeres and adversity: Too toxic to ignore. Nature. 2012 Oct 11; 490(7419):169-71.
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      26. Beery AK, Lin J, Biddle JS, Francis DD, Blackburn EH, Epel ES. Chronic stress elevates telomerase activity in rats. Biol Lett. 2012 Dec 23; 8(6):1063-6.
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      27. Kiecolt-Glaser JK, Epel ES, Belury MA, Andridge R, Lin J, Glaser R, Malarkey WB, Hwang BS, Blackburn E. Omega-3 fatty acids, oxidative stress, and leukocyte telomere length: A randomized controlled trial. Brain Behav Immun. 2013 Feb; 28:16-24.
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      28. Armanios M, Blackburn EH. The telomere syndromes. Nat Rev Genet. 2012 Oct; 13(10):693-704.
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      29. Adler N, Pantell MS, O'Donovan A, Blackburn E, Cawthon R, Koster A, Opresko P, Newman A, Harris TB, Epel E. Educational attainment and late life telomere length in the Health, Aging and Body Composition Study. Brain Behav Immun. 2013 Jan; 27(1):15-21.
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      30. Needham BL, Fernandez JR, Lin J, Epel ES, Blackburn EH. Socioeconomic status and cell aging in children. Soc Sci Med. 2012 Jun; 74(12):1948-51.
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      31. Lavretsky H, Epel ES, Siddarth P, Nazarian N, Cyr NS, Khalsa DS, Lin J, Blackburn E, Irwin MR. A pilot study of yogic meditation for family dementia caregivers with depressive symptoms: effects on mental health, cognition, and telomerase activity. Int J Geriatr Psychiatry. 2013 Jan; 28(1):57-65.
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      32. O'Donovan A, Tomiyama AJ, Lin J, Puterman E, Adler NE, Kemeny M, Wolkowitz OM, Blackburn EH, Epel ES. Stress appraisals and cellular aging: a key role for anticipatory threat in the relationship between psychological stress and telomere length. Brain Behav Immun. 2012 May; 26(4):573-9.
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      33. Daubenmier J, Lin J, Blackburn E, Hecht FM, Kristeller J, Maninger N, Kuwata M, Bacchetti P, Havel PJ, Epel E. Changes in stress, eating, and metabolic factors are related to changes in telomerase activity in a randomized mindfulness intervention pilot study. Psychoneuroendocrinology. 2012 Jul; 37(7):917-28.
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      34. Tomiyama AJ, O'Donovan A, Lin J, Puterman E, Lazaro A, Chan J, Dhabhar FS, Wolkowitz O, Kirschbaum C, Blackburn E, Epel E. Does cellular aging relate to patterns of allostasis? An examination of basal and stress reactive HPA axis activity and telomere length. Physiol Behav. 2012 Apr 12; 106(1):40-5.
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      35. Krauss J, Farzaneh-Far R, Puterman E, Na B, Lin J, Epel E, Blackburn E, Whooley MA. Physical fitness and telomere length in patients with coronary heart disease: findings from the Heart and Soul Study. PLoS One. 2011; 6(11):e26983.
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      36. Kroenke CH, Pletcher MJ, Lin J, Blackburn E, Adler N, Matthews K, Epel E. Telomerase, telomere length, and coronary artery calcium in black and white men in the CARDIA study. Atherosclerosis. 2012 Feb; 220(2):506-12.
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      37. Prather AA, Puterman E, Lin J, O'Donovan A, Krauss J, Tomiyama AJ, Epel ES, Blackburn EH. Shorter leukocyte telomere length in midlife women with poor sleep quality. J Aging Res. 2011; 2011:721390.
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      38. Njajou OT, Cawthon RM, Blackburn EH, Harris TB, Li R, Sanders JL, Newman AB, Nalls M, Cummings SR, Hsueh WC. Shorter telomeres are associated with obesity and weight gain in the elderly. Int J Obes (Lond). 2012 Sep; 36(9):1176-9.
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      39. Brydon L, Lin J, Butcher L, Hamer M, Erusalimsky JD, Blackburn EH, Steptoe A. Hostility and cellular aging in men from the Whitehall II cohort. Biol Psychiatry. 2012 May 1; 71(9):767-73.
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      40. Blackburn EH. Actuary of the cell. Interview by Thea Singer. Sci Am. 2011 Oct; 305(4):84-7.
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      41. Kroenke CH, Epel E, Adler N, Bush NR, Obradovic J, Lin J, Blackburn E, Stamperdahl JL, Boyce WT. Autonomic and adrenocortical reactivity and buccal cell telomere length in kindergarten children. Psychosom Med. 2011 Sep; 73(7):533-40.
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      42. Lin J, Epel E, Blackburn E. Telomeres and lifestyle factors: roles in cellular aging. Mutat Res. 2012 Feb 1; 730(1-2):85-9.
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      43. Aviv A, Hunt SC, Lin J, Cao X, Kimura M, Blackburn E. Impartial comparative analysis of measurement of leukocyte telomere length/DNA content by Southern blots and qPCR. Nucleic Acids Res. 2011 Nov 1; 39(20):e134.
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      44. Entringer S, Epel ES, Kumsta R, Lin J, Hellhammer DH, Blackburn EH, Wüst S, Wadhwa PD. Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood. Proc Natl Acad Sci U S A. 2011 Aug 16; 108(33):E513-8.
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      45. Blackburn EH. Cancer interception. Cancer Prev Res (Phila). 2011 Jun; 4(6):787-92.
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      46. Hoen PW, de Jonge P, Na BY, Farzaneh-Far R, Epel E, Lin J, Blackburn E, Whooley MA. Depression and leukocyte telomere length in patients with coronary heart disease: data from the Heart and Soul Study. Psychosom Med. 2011 Sep; 73(7):541-7.
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      47. O'Donovan A, Pantell MS, Puterman E, Dhabhar FS, Blackburn EH, Yaffe K, Cawthon RM, Opresko PL, Hsueh WC, Satterfield S, Newman AB, Ayonayon HN, Rubin SM, Harris TB, Epel ES. Cumulative inflammatory load is associated with short leukocyte telomere length in the Health, Aging and Body Composition Study. PLoS One. 2011; 6(5):e19687.
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      48. Blackburn EH, Collins K. Telomerase: an RNP enzyme synthesizes DNA. Cold Spring Harb Perspect Biol. 2011 May; 3(5).
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      49. Steptoe A, Hamer M, Butcher L, Lin J, Brydon L, Kivimäki M, Marmot M, Blackburn E, Erusalimsky JD. Educational attainment but not measures of current socioeconomic circumstances are associated with leukocyte telomere length in healthy older men and women. Brain Behav Immun. 2011 Oct; 25(7):1292-8.
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      50. O'Donovan A, Epel E, Lin J, Wolkowitz O, Cohen B, Maguen S, Metzler T, Lenoci M, Blackburn E, Neylan TC. Childhood trauma associated with short leukocyte telomere length in posttraumatic stress disorder. Biol Psychiatry. 2011 Sep 1; 70(5):465-71.
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      51. Blackburn EH. Walking the walk from genes through telomere maintenance to cancer risk. Cancer Prev Res (Phila). 2011 Apr; 4(4):473-5.
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      52. Wolkowitz OM, Mellon SH, Epel ES, Lin J, Dhabhar FS, Su Y, Reus VI, Rosser R, Burke HM, Kupferman E, Compagnone M, Nelson JC, Blackburn EH. Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings. PLoS One. 2011; 6(3):e17837.
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      53. Humphreys J, Epel ES, Cooper BA, Lin J, Blackburn EH, Lee KA. Telomere shortening in formerly abused and never abused women. Biol Res Nurs. 2012 Apr; 14(2):115-23.
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      54. Wolkowitz OM, Mellon SH, Epel ES, Lin J, Reus VI, Rosser R, Burke H, Compagnone M, Nelson JC, Dhabhar FS, Blackburn EH. Resting leukocyte telomerase activity is elevated in major depression and predicts treatment response. Mol Psychiatry. 2012 Feb; 17(2):164-72.
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      55. Jacobs TL, Epel ES, Lin J, Blackburn EH, Wolkowitz OM, Bridwell DA, Zanesco AP, Aichele SR, Sahdra BK, MacLean KA, King BG, Shaver PR, Rosenberg EL, Ferrer E, Wallace BA, Saron CD. Intensive meditation training, immune cell telomerase activity, and psychological mediators. Psychoneuroendocrinology. 2011 Jun; 36(5):664-81.
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      56. Lin J, Kroenke CH, Epel E, Kenna HA, Wolkowitz OM, Blackburn E, Rasgon NL. Greater endogenous estrogen exposure is associated with longer telomeres in postmenopausal women at risk for cognitive decline. Brain Res. 2011 Mar 16; 1379:224-31.
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      57. Blackburn EH. Telomeres and telomerase: the means to the end (Nobel lecture). Angew Chem Int Ed Engl. 2010 Oct 4; 49(41):7405-21.
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      58. Njajou OT, Blackburn EH, Pawlikowska L, Mangino M, Damcott CM, Kwok PY, Spector TD, Newman AB, Harris TB, Cummings SR, Cawthon RM, Shuldiner AR, Valdes AM, Hsueh WC. A common variant in the telomerase RNA component is associated with short telomere length. PLoS One. 2010; 5(9):e13048.
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      59. Fraser JA, Madhumalar A, Blackburn E, Bramham J, Walkinshaw MD, Verma C, Hupp TR. A novel p53 phosphorylation site within the MDM2 ubiquitination signal: II. a model in which phosphorylation at SER269 induces a mutant conformation to p53. J Biol Chem. 2010 Nov 26; 285(48):37773-86.
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      60. Williams TL, Levy DL, Maki-Yonekura S, Yonekura K, Blackburn EH. Characterization of the yeast telomere nucleoprotein core: Rap1 binds independently to each recognition site. J Biol Chem. 2010 Nov 12; 285(46):35814-24.
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      61. Stohr BA, Xu L, Blackburn EH. The terminal telomeric DNA sequence determines the mechanism of dysfunctional telomere fusion. Mol Cell. 2010 Jul 30; 39(2):307-14.
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      62. Puterman E, Lin J, Blackburn E, O'Donovan A, Adler N, Epel E. The power of exercise: buffering the effect of chronic stress on telomere length. PLoS One. 2010; 5(5):e10837.
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      63. Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, Berenbaum MR, Berlin OB, Bjorkman PJ, Blackburn E, Blamont JE, Botchan MR, Boyer JS, Boyle EA, Branton D, Briggs SP, Briggs WR, Brill WJ, Britten RJ, Broecker WS, Brown JH, Brown PO, Brunger AT, Cairns J, Canfield DE, Carpenter SR, Carrington JC, Cashmore AR, Castilla JC, Cazenave A, Chapin FS, Ciechanover AJ, Clapham DE, Clark WC, Clayton RN, Coe MD, Conwell EM, Cowling EB, Cowling RM, Cox CS, Croteau RB, Crothers DM, Crutzen PJ, Daily GC, Dalrymple GB, Dangl JL, Darst SA, Davies DR, Davis MB, De Camilli PV, Dean C, DeFries RS, Deisenhofer J, Delmer DP, DeLong EF, DeRosier DJ, Diener TO, Dirzo R, Dixon JE, Donoghue MJ, Doolittle RF, Dunne T, Ehrlich PR, Eisenstadt SN, Eisner T, Emanuel KA, Englander SW, Ernst WG, Falkowski PG, Feher G, Ferejohn JA, Fersht A, Fischer EH, Fischer R, Flannery KV, Frank J, Frey PA, Fridovich I, Frieden C, Futuyma DJ, Gardner WR, Garrett CJ, Gilbert W, Goldberg RB, Goodenough WH, Goodman CS, Goodman M, Greengard P, Hake S, Hammel G, Hanson S, Harrison SC, Hart SR, Hartl DL, Haselkorn R, Hawkes K, Hayes JM, Hille B, Hökfelt T, House JS, Hout M, Hunten DM, Izquierdo IA, Jagendorf AT, Janzen DH, Jeanloz R, Jencks CS, Jury WA, Kaback HR, Kailath T, Kay P, Kay SA, Kennedy D, Kerr A, Kessler RC, Khush GS, Kieffer SW, Kirch PV, Kirk K, Kivelson MG, Klinman JP, Klug A, Knopoff L, Kornberg H, Kutzbach JE, Lagarias JC, Lambeck K, Landy A, Langmuir CH, Larkins BA, Le Pichon XT, Lenski RE, Leopold EB, Levin SA, Levitt M, Likens GE, Lippincott-Schwartz J, Lorand L, Lovejoy CO, Lynch M, Mabogunje AL, Malone TF, Manabe S, Marcus J, Massey DS, McWilliams JC, Medina E, Melosh HJ, Meltzer DJ, Michener CD, Miles EL, Mooney HA, Moore PB, Morel FM, Mosley-Thompson ES, Moss B, Munk WH, Myers N, Nair GB, Nathans J, Nester EW, Nicoll RA, Novick RP, O'Connell JF, Olsen PE, Opdyke ND, Oster GF, Ostrom E, Pace NR, Paine RT, Palmiter RD, Pedlosky J, Petsko GA, Pettengill GH, Philander SG, Piperno DR, Pollard TD, Price PB, Reichard PA, Reskin BF, Ricklefs RE, Rivest RL, Roberts JD, Romney AK, Rossmann MG, Russell DW, Rutter WJ, Sabloff JA, Sagdeev RZ, Sahlins MD, Salmond A, Sanes JR, Schekman R, Schellnhuber J, Schindler DW, Schmitt J, Schneider SH, Schramm VL, Sederoff RR, Shatz CJ, Sherman F, Sidman RL, Sieh K, Simons EL, Singer BH, Singer MF, Skyrms B, Sleep NH, Smith BD, Snyder SH, Sokal RR, Spencer CS, Steitz TA, Strier KB, Südhof TC, Taylor SS, Terborgh J, Thomas DH, Thompson LG, Tjian RT, Turner MG, Uyeda S, Valentine JW, Valentine JS, Van Etten JL, van Holde KE, Vaughan M, Verba S, von Hippel PH, Wake DB, Walker A, Walker JE, Watson EB, Watson PJ, Weigel D, Wessler SR, West-Eberhard MJ, White TD, Wilson WJ, Wolfenden RV, Wood JA, Woodwell GM, Wright HE, Wu C, Wunsch C, Zoback ML. Climate change and the integrity of science. Science. 2010 May 7; 328(5979):689-90.
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      64. Blackburn EH, Tlsty TD, Lippman SM. Unprecedented opportunities and promise for cancer prevention research. Cancer Prev Res (Phila). 2010 Apr; 3(4):394-402.
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      65. Blackburn EH. Highlighting the science of cancer prevention. Cancer Prev Res (Phila). 2010 Apr; 3(4):393.
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      66. Worrall EG, Worrall L, Blackburn E, Walkinshaw M, Hupp TR. The effects of phosphomimetic lid mutation on the thermostability of the N-terminal domain of MDM2. J Mol Biol. 2010 May 7; 398(3):414-28.
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      67. Farzaneh-Far R, Lin J, Epel ES, Harris WS, Blackburn EH, Whooley MA. Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease. JAMA. 2010 Jan 20; 303(3):250-7.
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      68. Farzaneh-Far R, Lin J, Epel E, Lapham K, Blackburn E, Whooley MA. Telomere length trajectory and its determinants in persons with coronary artery disease: longitudinal findings from the heart and soul study. PLoS One. 2010; 5(1):e8612.
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      69. Epel ES, Lin J, Dhabhar FS, Wolkowitz OM, Puterman E, Karan L, Blackburn EH. Dynamics of telomerase activity in response to acute psychological stress. Brain Behav Immun. 2010 May; 24(4):531-9.
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      70. Blackburn E, Greider C, Yonath A, Ostrom E. 2009 Nobels: break or breakthrough for women? Interview by Jeffrey Mervis and Kate Travis. Science. 2009 Oct 30; 326(5953):656-8.
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      71. Lin J, Epel E, Cheon J, Kroenke C, Sinclair E, Bigos M, Wolkowitz O, Mellon S, Blackburn E. Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenance. J Immunol Methods. 2010 Jan 31; 352(1-2):71-80.
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      72. Blackburn E. Telomeres and Tetrahymena: an interview with Elizabeth Blackburn. Dis Model Mech. 2009 Nov-Dec; 2(11-12):534-7.
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      73. Makovets S, Blackburn EH. DNA damage signalling prevents deleterious telomere addition at DNA breaks. Nat Cell Biol. 2009 Nov; 11(11):1383-6.
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      74. Epel E, Daubenmier J, Moskowitz JT, Folkman S, Blackburn E. Can meditation slow rate of cellular aging? Cognitive stress, mindfulness, and telomeres. Ann N Y Acad Sci. 2009 Aug; 1172:34-53.
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      75. Njajou OT, Hsueh WC, Blackburn EH, Newman AB, Wu SH, Li R, Simonsick EM, Harris TM, Cummings SR, Cawthon RM. Association between telomere length, specific causes of death, and years of healthy life in health, aging, and body composition, a population-based cohort study. J Gerontol A Biol Sci Med Sci. 2009 Aug; 64(8):860-4.
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      76. Blackburn E. A conversation with Elizabeth Blackburn. Interview by Misia Landau. Clin Chem. 2009 Apr; 55(4):835-41.
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      77. Li S, Makovets S, Matsuguchi T, Blethrow JD, Shokat KM, Blackburn EH. Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression. Cell. 2009 Jan 9; 136(1):50-61.
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      78. O'Donovan A, Lin J, Tillie J, Tillie JM, Dhabhar FS, Wolkowitz OM, Wolkowitz O, Blackburn EH, Blackburn E, Epel ES, Epel E. Pessimism correlates with leukocyte telomere shortness and elevated interleukin-6 in post-menopausal women. Brain Behav Immun. 2009 May; 23(4):446-9.
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      79. Anderson CM, Blackburn EH. Mec1 function in the DNA damage response does not require its interaction with Tel2. Cell Cycle. 2008 Dec; 7(23):3695-8.
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      80. Epel ES, Merkin SS, Cawthon R, Blackburn EH, Adler NE, Pletcher MJ, Seeman TE. The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men. Aging (Albany NY). 2009 Jan; 1(1):81-8.
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      81. Wang X, Kam Z, Carlton PM, Xu L, Sedat JW, Blackburn EH. Rapid telomere motions in live human cells analyzed by highly time-resolved microscopy. Epigenetics Chromatin. 2008; 1(1):4.
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      82. Kiefer A, Lin J, Blackburn E, Epel E. Dietary restraint and telomere length in pre- and postmenopausal women. Psychosom Med. 2008 Oct; 70(8):845-9.
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      83. Ornish D, Lin J, Daubenmier J, Weidner G, Epel E, Kemp C, Magbanua MJ, Marlin R, Yglecias L, Carroll PR, Blackburn EH. Increased telomerase activity and comprehensive lifestyle changes: a pilot study. Lancet Oncol. 2008 Nov; 9(11):1048-57.
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      84. Seidel JJ, Anderson CM, Blackburn EH. A novel Tel1/ATM N-terminal motif, TAN, is essential for telomere length maintenance and a DNA damage response. Mol Cell Biol. 2008 Sep; 28(18):5736-46.
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      222. Henderson E, Hardin CC, Walk SK, Tinoco I, Blackburn EH. Telomeric DNA oligonucleotides form novel intramolecular structures containing guanine-guanine base pairs. Cell. 1987 Dec 24; 51(6):899-908.
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      223. Greider CW, Blackburn EH. The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity. Cell. 1987 Dec 24; 51(6):887-98.
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      224. Forney J, Henderson ER, Blackburn EH. Identification of the telomeric sequence of the acellular slime molds Didymium iridis and Physarum polycephalum. Nucleic Acids Res. 1987 Nov 25; 15(22):9143-52.
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      225. Budarf M, Blackburn E. S1 nuclease sensitivity of a double-stranded telomeric DNA sequence. Nucleic Acids Res. 1987 Aug 11; 15(15):6273-92.
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      226. Larson DD, Spangler EA, Blackburn EH. Dynamics of telomere length variation in Tetrahymena thermophila. Cell. 1987 Jul 31; 50(3):477-83.
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      227. Larson DD, Blackburn EH, Yaeger PC, Orias E. Control of rDNA replication in Tetrahymena involves a cis-acting upstream repeat of a promoter element. Cell. 1986 Oct 24; 47(2):229-40.
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      228. Challoner PB, Blackburn EH. Conservation of sequences adjacent to the telomeric C4A2 repeats of ciliate macronuclear ribosomal RNA gene molecules. Nucleic Acids Res. 1986 Aug 11; 14(15):6299-311.
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      229. Budarf ML, Blackburn EH. Chromatin structure of the telomeric region and 3'-nontranscribed spacer of Tetrahymena ribosomal RNA genes. J Biol Chem. 1986 Jan 5; 261(1):363-9.
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      230. Blackburn EH, Karrer KM. Genomic reorganization in ciliated protozoans. Annu Rev Genet. 1986; 20:501-21.
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      231. Greider CW, Blackburn EH. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell. 1985 Dec; 43(2 Pt 1):405-13.
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      232. Cherry JM, Blackburn EH. The internally located telomeric sequences in the germ-line chromosomes of Tetrahymena are at the ends of transposon-like elements. Cell. 1985 Dec; 43(3 Pt 2):747-58.
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      233. Howard EA, Blackburn EH. Reproducible and variable genomic rearrangements occur in the developing somatic nucleus of the ciliate Tetrahymena thermophila. Mol Cell Biol. 1985 Aug; 5(8):2039-50.
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      234. Spangler EA, Blackburn EH. The nucleotide sequence of the 17S ribosomal RNA gene of Tetrahymena thermophila and the identification of point mutations resulting in resistance to the antibiotics paromomycin and hygromycin. J Biol Chem. 1985 May 25; 260(10):6334-40.
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      235. Bruns PJ, Katzen AL, Martin L, Blackburn EH. A drug-resistant mutation in the ribosomal DNA of Tetrahymena. Proc Natl Acad Sci U S A. 1985 May; 82(9):2844-6.
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      236. Challoner PB, Amin AA, Pearlman RE, Blackburn EH. Conserved arrangements of repeated DNA sequences in nontranscribed spacers of ciliate ribosomal RNA genes: evidence for molecular coevolution. Nucleic Acids Res. 1985 Apr 11; 13(7):2661-80.
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      237. Shampay J, Szostak JW, Blackburn EH. DNA sequences of telomeres maintained in yeast. Nature. 1984 Jul 12-18; 310(5973):154-7.
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      238. Blackburn EH. Telomeres: do the ends justify the means? Cell. 1984 May; 37(1):7-8.
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      239. Blackburn EH, Challoner PB. Identification of a telomeric DNA sequence in Trypanosoma brucei. Cell. 1984 Feb; 36(2):447-57.
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      240. Blackburn EH. The molecular structure of centromeres and telomeres. Annu Rev Biochem. 1984; 53:163-94.
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      241. Blackburn EH, Pan WC, Johnson CC. Methylation of ribosomal RNA genes in the macronucleus of Tetrahymena thermophila. Nucleic Acids Res. 1983 Aug 11; 11(15):5131-45.
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      242. Blackburn EH, Budarf ML, Challoner PB, Cherry JM, Howard EA, Katzen AL, Pan WC, Ryan T. DNA termini in ciliate macronuclei. Cold Spring Harb Symp Quant Biol. 1983; 47 Pt 2:1195-207.
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      243. Szostak JW, Blackburn EH. Cloning yeast telomeres on linear plasmid vectors. Cell. 1982 May; 29(1):245-55.
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      244. Pan WC, Orias E, Flacks M, Blackburn EH. Allele-specific, selective amplification of a ribosomal RNA gene in Tetrahymena thermophila. Cell. 1982 Mar; 28(3):595-604.
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      245. Yao MC, Blackburn E, Gall J. Tandemly repeated C-C-C-C-A-A hexanucleotide of Tetrahymena rDNA is present elsewhere in the genome and may be related to the alteration of the somatic genome. J Cell Biol. 1981 Aug; 90(2):515-20.
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      246. Katzen AL, Cann GM, Blackburn EH. Sequence-specific fragmentation of macronuclear DNA in a holotrichous ciliate. Cell. 1981 May; 24(2):313-20.
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      247. Blackburn EH, Chiou SS. Non-nucleosomal packaging of a tandemly repeated DNA sequence at termini of extrachromosomal DNA coding for rRNA in Tetrahymena. Proc Natl Acad Sci U S A. 1981 Apr; 78(4):2263-7.
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      248. Pan WC, Blackburn EH. Single extrachromosomal ribosomal RNA gene copies are synthesized during amplification of the rDNA in Tetrahymena. Cell. 1981 Feb; 23(2):459-66.
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      249. Yao MC, Blackburn E, Gall JG. Amplification of the rRNA genes in Tetrahymena. Cold Spring Harb Symp Quant Biol. 1979; 43 Pt 2:1293-6.
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      250. Blackburn EH, Gall JG. A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena. J Mol Biol. 1978 Mar 25; 120(1):33-53.
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      251. Air GM, Blackburn EH, Coulson AR, Galibert F, Sanger F, Sedat JW, Ziff EB. Gene F of bacteriophage phiX174. Correlation of nucleotide sequences from the DNA and amino acid sequences from the gene product. J Mol Biol. 1976 Nov 15; 107(4):445-58.
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      252. Blackburn EH. Transcription and sequence analysis of a fragment of bacteriophage phiX174 DNA. J Mol Biol. 1976 Nov 15; 107(4):417-31.
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      253. Air GM, Blackburn EH, Sanger F, Coulson AR. The nucleotide and amino acid sequences of the N (5') terminal region of gene G of bacteriophage phiphiX 174. J Mol Biol. 1975 Aug 25; 96(4):703-19.
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      254. Blackburn EH. Transcription by Escherichia coli RNA polymerase of a single-stranded fragment by bacteriophage phiX174 DNA 48 residues in length. J Mol Biol. 1975 Apr 15; 93(3):367-74.
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