Ken Nakamura, MD, PhD

Title(s)Professor, Neurology
SchoolSchool of Medicine
Address35 Medical Center Way, #1038
San Francisco CA 94143
Phone415-734-2550
ORCID ORCID Icon0000-0002-9192-182X Additional info
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


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    Dr. Ken Nakamura is a neurologist who specializes in diagnosing and treating patients with Parkinson’s disease at the Parkinson’s Disease and Movement Disorders Clinic. He also runs a research laboratory at the Gladstone Institutes, where he investigates how disruptions of mitochondria—the “power centers” of cells that convert nutrients into energy—contribute to the development and progression of Parkinson’s disease and Alzheimer’s disease.

    Nakamura earned a bachelor’s degree in chemistry and biological sciences from Cornell University, and an MD and PhD in neurobiology from the University of Chicago. His thesis work focused on the role of oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson’s disease. Nakamura then completed an internship in internal medicine and a residency in neurology at UCSF, and a clinical fellowship in movement disorders at UCSF and the San Francisco VA Medical Center. He also completed a research fellowship at UCSF, during which he investigated how alpha-synuclein disrupts mitochondrial morphology and function and contributes to the development of Parkinson’s disease. He has received several awards, including a Burroughs Wellcome Fund Career Award for Medical Scientists.

    Collapse Research 
    Collapse Research Activities and Funding
    Defining Strategies to Target Energy Failure in Metabolically Vulnerable Human Cells
    NIH R01AG065428Aug 1, 2020 - Apr 30, 2025
    Role: Principal Investigator
    Understand and probing disrupted glucose metabolism in Alzheimer's disease
    NIH/NIA R01AG064170Aug 1, 2019 - Mar 31, 2024
    Role: Principal Investigator
    Understand and probing disrupted glucose metabolism in Alzheimer's disease
    NIH RF1AG064170Aug 1, 2019 - Mar 31, 2024
    Role: Principal Investigator
    Determining how neural activity impairs bioenergetics in PD pathogenesis
    NIH R01NS091902Apr 1, 2015 - Mar 31, 2020
    Role: Principal Investigator
    Regulation of mitochondrial morphology by alpha-synuclein
    NIH K08NS062954Jul 1, 2009 - Jun 30, 2014
    Role: Principal Investigator
    GLUTATHIONE AND DOPAMINERGIC NEURONAL SURVIVAL
    NIH F30MH011986Jul 1, 1998
    Role: Principal Investigator
    RCMI CLINICAL RESEARCH INFRASTRUCTURE INITIATIVE (RCRII)
    NIH P20RR011091Sep 30, 1995 - Jan 31, 2011
    Role: Co-Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Protocol to combine brain sections from multiple mice into a single block for spatial transcriptomic analyses. STAR Protoc. 2023 Dec 15; 4(4):102617. Sei YJ, Chaumeil MM, Nakamura K. PMID: 37742175; PMCID: PMC10523026.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    2. Neurons require glucose uptake and glycolysis in vivo. Cell Rep. 2023 04 25; 42(4):112335. Li H, Guglielmetti C, Sei YJ, Zilberter M, Le Page LM, Shields L, Yang J, Nguyen K, Tiret B, Gao X, Bennett N, Lo I, Dayton TL, Kampmann M, Huang Y, Rathmell JC, Vander Heiden M, Chaumeil MM, Nakamura K. PMID: 37027294; PMCID: PMC10556202.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    3. Ensembles of endothelial and mural cells promote angiogenesis in prenatal human brain. Cell. 2022 09 29; 185(20):3753-3769.e18. Crouch EE, Bhaduri A, Andrews MG, Cebrian-Silla A, Diafos LN, Birrueta JO, Wedderburn-Pugh K, Valenzuela EJ, Bennett NK, Eze UC, Sandoval-Espinosa C, Chen J, Mora C, Ross JM, Howard CE, Gonzalez-Granero S, Lozano JF, Vento M, Haeussler M, Paredes MF, Nakamura K, Garcia-Verdugo JM, Alvarez-Buylla A, Kriegstein AR, Huang EJ. PMID: 36179668; PMCID: PMC9550196.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    4. Primary and metastatic tumors exhibit systems-level differences in dependence on mitochondrial respiratory function. PLoS Biol. 2022 09; 20(9):e3001753. Bennett NK, Nakaoka HJ, Laurent D, Okimoto RA, Sei Y, Horvai AE, Bivona TG, Ten Hoeve J, Graeber TG, Nakamura K, Nakamura JL. PMID: 36137002; PMCID: PMC9498964.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Biallelic pathogenic variants in COX11 are associated with an infantile-onset mitochondrial encephalopathy. Hum Mutat. 2022 12; 43(12):1970-1978. Rius R, Bennett NK, Bhattacharya K, Riley LG, Yüksel Z, Formosa LE, Compton AG, Dale RC, Cowley MJ, Gayevskiy V, Al Tala SM, Almehery AA, Ryan MT, Thorburn DR, Nakamura K, Christodoulou J. PMID: 36030551; PMCID: PMC9771894.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    6. Reader Response: Safety of AADC Gene Therapy for Moderately Advanced Parkinson Disease: Three-Year Outcomes From the PD-1101 Trial. Neurology. 2022 08 09; 99(6):258-259. Kang UJ, Nakamura K, Zhuang X. PMID: 35940895; PMCID: PMC10499428.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Isoflurane inhibition of endocytosis is an anesthetic mechanism of action. Curr Biol. 2022 07 25; 32(14):3016-3032.e3. Jung S, Zimin PI, Woods CB, Kayser EB, Haddad D, Reczek CR, Nakamura K, Ramirez JM, Sedensky MM, Morgan PG. PMID: 35688155; PMCID: PMC9329204.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    8. Mouse midbrain dopaminergic neurons survive loss of the PD-associated mitochondrial protein CHCHD2. Hum Mol Genet. 2022 05 04; 31(9):1500-1518. Nguyen MK, McAvoy K, Liao SC, Doric Z, Lo I, Li H, Manfredi G, Nakamura K. PMID: 34791217; PMCID: PMC9071413.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    9. The PINK1 advantage: recycling mitochondria in times of trouble? Autophagy. 2022 01; 18(1):231-232. Doric Z, Li H, Nakamura K. PMID: 34812108; PMCID: PMC8865287.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    10. Mice with disrupted mitochondria used to model Parkinson's disease. Nature. 2021 11; 599(7886):558-560. Doric Z, Nakamura K. PMID: 34732876.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    11. Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration. Nat Commun. 2021 09 06; 12(1):5284. Linsley JW, Shah K, Castello N, Chan M, Haddad D, Doric Z, Wang S, Leks W, Mancini J, Oza V, Javaherian A, Nakamura K, Kokel D, Finkbeiner S. PMID: 34489414; PMCID: PMC8421388.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    12. Longitudinal tracking of neuronal mitochondria delineates PINK1/Parkin-dependent mechanisms of mitochondrial recycling and degradation. Sci Adv. 2021 Aug; 7(32). Li H, Doric Z, Berthet A, Jorgens DM, Nguyen MK, Hsieh I, Margulis J, Fang R, Debnath J, Sesaki H, Finkbeiner S, Huang E, Nakamura K. PMID: 34362731; PMCID: PMC8346224.
      View in: PubMed   Mentions: 6     Fields:    
    13. SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19. Sci Transl Med. 2021 04 21; 13(590). Perez-Bermejo JA, Kang S, Rockwood SJ, Simoneau CR, Joy DA, Silva AC, Ramadoss GN, Flanigan WR, Fozouni P, Li H, Chen PY, Nakamura K, Whitman JD, Hanson PJ, McManus BM, Ott M, Conklin BR, McDevitt TC. PMID: 33723017; PMCID: PMC8128284.
      View in: PubMed   Mentions: 118     Fields:    Translation:HumansCells
    14. Mitochondrial fission is a critical modulator of mutant APP-induced neural toxicity. J Biol Chem. 2021 Jan-Jun; 296:100469. Shields LY, Li H, Nguyen K, Kim H, Doric Z, Garcia JH, Gill TM, Haddad D, Vossel K, Calvert M, Nakamura K. PMID: 33639169; PMCID: PMC8042169.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    15. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021 Jan; 17(1):1-382. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, Ávalos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, Bánréti Á, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Barilà D, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC, Basu A, Batoko H, Batten I, Baulieu EE, Baumgarner BL, Bayry J, Beale R, Beau I, Beaumatin F, Bechara LRG, Beck GR, Beers MF, Begun J, Behrends C, Behrens GMN, Bei R, Bejarano E, Bel S, Behl C, Belaid A, Belgareh-Touzé N, Bellarosa C, Belleudi F, Belló Pérez M, Bello-Morales R, Beltran JSO, Beltran S, Benbrook DM, Bendorius M, Benitez BA, Benito-Cuesta I, Bensalem J, Berchtold MW, Berezowska S, Bergamaschi D, Bergami M, Bergmann A, Berliocchi L, Berlioz-Torrent C, Bernard A, Berthoux L, Besirli CG, Besteiro S, Betin VM, Beyaert R, Bezbradica JS, Bhaskar K, Bhatia-Kissova I, Bhattacharya R, Bhattacharya S, Bhattacharyya S, Bhuiyan MS, Bhutia SK, Bi L, Bi X, Biden TJ, Bijian K, Billes VA, Binart N, Bincoletto C, Birgisdottir AB, Bjorkoy G, Blanco G, Blas-Garcia A, Blasiak J, Blomgran R, Blomgren K, Blum JS, Boada-Romero E, Boban M, Boesze-Battaglia K, Boeuf P, Boland B, Bomont P, Bonaldo P, Bonam SR, Bonfili L, Bonifacino JS, Boone BA, Bootman MD, Bordi M, Borner C, Bornhauser BC, Borthakur G, Bosch J, Bose S, Botana LM, Botas J, Boulanger CM, Boulton ME, Bourdenx M, Bourgeois B, Bourke NM, Bousquet G, Boya P, Bozhkov PV, Bozi LHM, Bozkurt TO, Brackney DE, Brandts CH, Braun RJ, Braus GH, Bravo-Sagua R, Bravo-San Pedro JM, Brest P, Bringer MA, Briones-Herrera A, Broaddus VC, Brodersen P, Brodsky JL, Brody SL, Bronson PG, Bronstein JM, Brown CN, Brown RE, Brum PC, Brumell JH, Brunetti-Pierri N, Bruno D, Bryson-Richardson RJ, Bucci C, Buchrieser C, Bueno M, Buitrago-Molina LE, Buraschi S, Buch S, Buchan JR, Buckingham EM, Budak H, Budini M, Bultynck G, Burada F, Burgoyne JR, Burón MI, Bustos V, Büttner S, Butturini E, Byrd A, Cabas I, Cabrera-Benitez S, Cadwell K, Cai J, Cai L, Cai Q, Cairó M, Calbet JA, Caldwell GA, Caldwell KA, Call JA, Calvani R, Calvo AC, Calvo-Rubio Barrera M, Camara NO, Camonis JH, Camougrand N, Campanella M, Campbell EM, Campbell-Valois FX, Campello S, Campesi I, Campos JC, Camuzard O, Cancino J, Candido de Almeida D, Canesi L, Caniggia I, et al. PMID: 33634751; PMCID: PMC7996087.
      View in: PubMed   Mentions: 870     Fields:    Translation:HumansAnimalsCells
    16. SARS-CoV-2 infection of human iPSC-derived cardiac cells predicts novel cytopathic features in hearts of COVID-19 patients. bioRxiv. 2020 Sep 12. Pérez-Bermejo JA, Kang S, Rockwood SJ, Simoneau CR, Joy DA, Ramadoss GN, Silva AC, Flanigan WR, Li H, Nakamura K, Whitman JD, Ott M, Conklin BR, McDevitt TC. PMID: 32935097; PMCID: PMC7491510.
      View in: PubMed   Mentions: 5  
    17. Defining the ATPome reveals cross-optimization of metabolic pathways. Nat Commun. 2020 08 28; 11(1):4319. Bennett NK, Nguyen MK, Darch MA, Nakaoka HJ, Cousineau D, Ten Hoeve J, Graeber TG, Schuelke M, Maltepe E, Kampmann M, Mendelsohn BA, Nakamura JL, Nakamura K. PMID: 32859923; PMCID: PMC7455733.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    18. Loss of HIPK2 Protects Neurons from Mitochondrial Toxins by Regulating Parkin Protein Turnover. J Neurosci. 2020 01 15; 40(3):557-568. Zhang J, Shang Y, Kamiya S, Kotowski SJ, Nakamura K, Huang EJ. PMID: 31776210; PMCID: PMC6961984.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    19. To be or not to be pink(1): contradictory findings in an animal model for Parkinson's disease. Brain Commun. 2019; 1(1):fcz016. de Haas R, Heltzel LCMW, Tax D, van den Broek P, Steenbreker H, Verheij MMM, Russel FGM, Orr AL, Nakamura K, Smeitink JAM. PMID: 31667474; PMCID: PMC6798789.
      View in: PubMed   Mentions: 13  
    20. A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure. PLoS Biol. 2018 08; 16(8):e2004624. Mendelsohn BA, Bennett NK, Darch MA, Yu K, Nguyen MK, Pucciarelli D, Nelson M, Horlbeck MA, Gilbert LA, Hyun W, Kampmann M, Nakamura JL, Nakamura K. PMID: 30148842; PMCID: PMC6110572.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    21. Mapping the Genetic Landscape of Human Cells. Cell. 2018 08 09; 174(4):953-967.e22. Horlbeck MA, Xu A, Wang M, Bennett NK, Park CY, Bogdanoff D, Adamson B, Chow ED, Kampmann M, Peterson TR, Nakamura K, Fischbach MA, Weissman JS, Gilbert LA. PMID: 30033366; PMCID: PMC6426455.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansCells
    22. A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling. Cell Syst. 2017 12 27; 5(6):564-577.e12. Malty RH, Aoki H, Kumar A, Phanse S, Amin S, Zhang Q, Minic Z, Goebels F, Musso G, Wu Z, Abou-Tok H, Meyer M, Deineko V, Kassir S, Sidhu V, Jessulat M, Scott NE, Xiong X, Vlasblom J, Prasad B, Foster LJ, Alberio T, Garavaglia B, Yu H, Bader GD, Nakamura K, Parkinson J, Babu M. PMID: 29128334; PMCID: PMC5746455.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    23. Long-term oral kinetin does not protect against α-synuclein-induced neurodegeneration in rodent models of Parkinson's disease. Neurochem Int. 2017 Oct; 109:106-116. Orr AL, Rutaganira FU, de Roulet D, Huang EJ, Hertz NT, Shokat KM, Nakamura K. PMID: 28434973; PMCID: PMC5641232.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    24. PINK1-Based Screen Shines Light on Autophagy Enhancers for Parkinson's Disease. Cell Chem Biol. 2017 04 20; 24(4):429-430. Haddad D, Nakamura K. PMID: 28431223; PMCID: PMC5845914.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    25. Understanding the susceptibility of dopamine neurons to mitochondrial stressors in Parkinson's disease. FEBS Lett. 2015 Dec 21; 589(24 Pt A):3702-13. Haddad D, Nakamura K. PMID: 26526613; PMCID: PMC4679488.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    26. The role of mitochondrially derived ATP in synaptic vesicle recycling. J Biol Chem. 2015 Sep 11; 290(37):22325-36. Pathak D, Shields LY, Mendelsohn BA, Haddad D, Lin W, Gerencser AA, Kim H, Brand MD, Edwards RH, Nakamura K. PMID: 26126824; PMCID: PMC4566209.
      View in: PubMed   Mentions: 128     Fields:    Translation:AnimalsCells
    27. Dynamin-related protein 1 is required for normal mitochondrial bioenergetic and synaptic function in CA1 hippocampal neurons. Cell Death Dis. 2015 Apr 16; 6:e1725. Shields LY, Kim H, Zhu L, Haddad D, Berthet A, Pathak D, Lam M, Ponnusamy R, Diaz-Ramirez LG, Gill TM, Sesaki H, Mucke L, Nakamura K. PMID: 25880092; PMCID: PMC4650558.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    28. Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons. J Neurosci. 2014 Oct 22; 34(43):14304-17. Berthet A, Margolis EB, Zhang J, Hsieh I, Zhang J, Hnasko TS, Ahmad J, Edwards RH, Sesaki H, Huang EJ, Nakamura K. PMID: 25339743; PMCID: PMC4205554.
      View in: PubMed   Mentions: 106     Fields:    Translation:AnimalsCells
    29. β-cell telomere attrition in diabetes: inverse correlation between HbA1c and telomere length. J Clin Endocrinol Metab. 2014 Aug; 99(8):2771-7. Tamura Y, Izumiyama-Shimomura N, Kimbara Y, Nakamura K, Ishikawa N, Aida J, Chiba Y, Mori S, Arai T, Aizawa T, Araki A, Takubo K, Ito H. PMID: 24735425.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    30. Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies. J Neurosci. 2014 Jan 08; 34(2):418-33. Skibinski G, Nakamura K, Cookson MR, Finkbeiner S. PMID: 24403142; PMCID: PMC3870929.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    31. SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK. Aging (Albany NY). 2013 Nov; 5(11):835-49. Ho L, Titus AS, Banerjee KK, George S, Lin W, Deota S, Saha AK, Nakamura K, Gut P, Verdin E, Kolthur-Seetharam U. PMID: 24296486; PMCID: PMC3868726.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    32. Energy failure: does it contribute to neurodegeneration? Ann Neurol. 2013 Oct; 74(4):506-16. Pathak D, Berthet A, Nakamura K. PMID: 24038413; PMCID: PMC4092015.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimalsCells
    33. The ubiquitin ligase parkin mediates resistance to intracellular pathogens. Nature. 2013 Sep 26; 501(7468):512-6. Manzanillo PS, Ayres JS, Watson RO, Collins AC, Souza G, Rae CS, Schneider DS, Nakamura K, Shiloh MU, Cox JS. PMID: 24005326; PMCID: PMC3886920.
      View in: PubMed   Mentions: 300     Fields:    Translation:AnimalsCells
    34. A neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1. Cell. 2013 Aug 15; 154(4):737-47. Hertz NT, Berthet A, Sos ML, Thorn KS, Burlingame AL, Nakamura K, Shokat KM. PMID: 23953109; PMCID: PMC3950538.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansAnimalsCells
    35. α-Synuclein and mitochondria: partners in crime? Neurotherapeutics. 2013 Jul; 10(3):391-9. Nakamura K. PMID: 23512373; PMCID: PMC3701775.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    36. Mitochondrial dynamics in neurodegeneration. Trends Cell Biol. 2013 Feb; 23(2):64-71. Itoh K, Nakamura K, Iijima M, Sesaki H. PMID: 23159640; PMCID: PMC3558617.
      View in: PubMed   Mentions: 253     Fields:    Translation:HumansAnimalsCells
    37. Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein. J Biol Chem. 2011 Jun 10; 286(23):20710-26. Nakamura K, Nemani VM, Azarbal F, Skibinski G, Levy JM, Egami K, Munishkina L, Zhang J, Gardner B, Wakabayashi J, Sesaki H, Cheng Y, Finkbeiner S, Nussbaum RL, Masliah E, Edwards RH. PMID: 21489994; PMCID: PMC3121472.
      View in: PubMed   Mentions: 300     Fields:    Translation:HumansAnimalsCells
    38. Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis. Neuron. 2010 Jan 14; 65(1):66-79. Nemani VM, Lu W, Berge V, Nakamura K, Onoa B, Lee MK, Chaudhry FA, Nicoll RA, Edwards RH. PMID: 20152114; PMCID: PMC3119527.
      View in: PubMed   Mentions: 536     Fields:    Translation:HumansAnimalsCells
    39. The behavior of alpha-synuclein in neurons. Mov Disord. 2010; 25 Suppl 1:S21-6. Fortin DL, Nemani VM, Nakamura K, Edwards RH. PMID: 20187244.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    40. Optical reporters for the conformation of alpha-synuclein reveal a specific interaction with mitochondria. J Neurosci. 2008 Nov 19; 28(47):12305-17. Nakamura K, Nemani VM, Wallender EK, Kaehlcke K, Ott M, Edwards RH. PMID: 19020024; PMCID: PMC6671709.
      View in: PubMed   Mentions: 103     Fields:    Translation:AnimalsCells
    41. Effects of unilateral subthalamic and pallidal deep brain stimulation on fine motor functions in Parkinson's disease. Mov Disord. 2007 Apr 15; 22(5):619-26. Nakamura K, Christine CW, Starr PA, Marks WJ. PMID: 17230483.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    42. Huntington's disease: clinical characteristics, pathogenesis and therapies. Drugs Today (Barc). 2007 Feb; 43(2):97-116. Nakamura K, Aminoff MJ. PMID: 17353947.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    43. Textbook of neural repair and rehabilitation (eds Selzer ME, Cohen L, Gage FH, Clarke S and Duncan PW). Trophic factor delivery by gene therapy. 2006; 532-547. Nakamura K Kang UJ.
    44. Lipid rafts mediate the synaptic localization of alpha-synuclein. J Neurosci. 2004 Jul 28; 24(30):6715-23. Fortin DL, Troyer MD, Nakamura K, Kubo S, Anthony MD, Edwards RH. PMID: 15282274; PMCID: PMC6729723.
      View in: PubMed   Mentions: 233     Fields:    Translation:HumansAnimalsCells
    45. Vitamin B12 deficiency. Arch Neurol. 2004 Jun; 61(6):960. Nakamura K, Mukherjee P, Swanson RA. PMID: 15210541.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    46. Potential of gene therapy for pediatric neurotransmitter diseases: lessons from Parkinson's disease. Ann Neurol. 2003; 54 Suppl 6:S103-9. Kang UJ, Nakamura K. PMID: 12891660.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    47. The localization and functional contribution of striatal aromatic L-amino acid decarboxylase to L-3,4-dihydroxyphenylalanine decarboxylation in rodent parkinsonian models. Cell Transplant. 2000 Sep-Oct; 9(5):567-76. Nakamura K, Ahmed M, Barr E, Leiden JM, Kang UJ. PMID: 11144954.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    48. Preferential resistance of dopaminergic neurons to glutathione depletion in a reconstituted nigrostriatal system. Brain Res. 2000 Aug 11; 873(2):203-11. Nakamura K, Won L, Heller A, Kang UJ. PMID: 10930545.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
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    53. Single core polypeptide in the reaction center of the photosynthetic bacterium Heliobacillus mobilis: structural implications and relations to other photosystems. Proc Natl Acad Sci U S A. 1993 Aug 01; 90(15):7124-8. Liebl U, Mockensturm-Wilson M, Trost JT, Brune DC, Blankenship RE, Vermaas W. PMID: 8346224; PMCID: PMC47088.
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