Kwun Wah Wen, MD, PhD

Address505 Parnassus Avenue
San Francisco CA 94117
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    1. Chen W, Sin SH, Wen KW, Damania B, Dittmer DP. Hsp90 inhibitors are efficacious against Kaposi Sarcoma by enhancing the degradation of the essential viral gene LANA, of the viral co-receptor EphA2 as well as other client proteins. PLoS Pathog. 2012; 8(11):e1003048. PMID: 23209418; PMCID: PMC3510261.
    2. Lei Y, Wen H, Yu Y, Taxman DJ, Zhang L, Widman DG, Swanson KV, Wen KW, Damania B, Moore CB, Giguère PM, Siderovski DP, Hiscott J, Razani B, Semenkovich CF, Chen X, Ting JP. The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. Immunity. 2012 Jun 29; 36(6):933-46. PMID: 22749352; PMCID: PMC3397828.
    3. Wen KW, Damania B. Hsp90 and Hsp40/Erdj3 are required for the expression and anti-apoptotic function of KSHV K1. Oncogene. 2010 Jun 17; 29(24):3532-44. PMID: 20418907; PMCID: PMC2908282.
    4. Wen KW, Damania B. Kaposi sarcoma-associated herpesvirus (KSHV): molecular biology and oncogenesis. Cancer Lett. 2010 Mar 28; 289(2):140-50. PMID: 19651473; PMCID: PMC4342847.
    5. Wen KW, Dittmer DP, Damania B. Disruption of LANA in rhesus rhadinovirus generates a highly lytic recombinant virus. J Virol. 2009 Oct; 83(19):9786-802. PMID: 19587030; PMCID: PMC2748027.
    6. Mahmud T, Wenzel SC, Wan E, Wen KW, Bode HB, Gaitatzis N, Müller R. A biosynthetic pathway to isovaleryl-CoA in myxobacteria: the involvement of the mevalonate pathway. Chembiochem. 2005 Feb; 6(2):322-30. PMID: 15619721.
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    7. Baguet A, Epler J, Wen KW, Bix M. A Leishmania major response locus identified by interval-specific congenic mapping of a T helper type 2 cell bias-controlling quantitative trait locus. J Exp Med. 2004 Dec 20; 200(12):1605-12. PMID: 15596523; PMCID: PMC2211989.
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