Jeffrey Lotz, PhD

Title(s)Professor, Orthopaedic Surgery
SchoolSchool of Medicine
Address513 Parnassus Ave, MSB, #1157
San Francisco CA 94117
Phone415-476-7881
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    Collapse Biography 
    Collapse Education and Training
    University of California, BerkeleyBS06/1979Mechanical Engineering
    Stanford University, Palo AltoMS06/1980Mechanical Engineering Design
    MIT/Harvard University, BostonPhD09/1988Medical Engineering
    Collapse Awards and Honors
    International Society for the Study of the Lumbar Spine2023ISSLS Prize for Low Back Pain Research
    UCSF Department of Orthopaedic Surgery2020Mentorship Award
    International Society for the Study of the Lumbar Spine2019ISSLS Prize for Low Back Pain Research
    North American Spine Society2018Henry Farfan Award for outstanding contributions in spine related basic science research
    EuroSpine2017Grammer/European Spine Journal Award
    International Society for the Study of the Lumbar Spine2017ISSLS Prize for Low Back Pain Research
    The Spine Journal and the North American Spine Society2017Outstanding Paper Award
    Orthopaedic Research Society Spine Section2015Founding Board Member, Treasurer
    International Society for the Study of the Lumbar Spine2013Best Paper Award (co-author)
    Orthopedics This Week2011Best New Technology in Spine Care (co-inventor)
    Philadelphia Spine Research Society2011Best Paper Award (co-author)
    American Institute for Medical and Biological Engineering2008Fellow
    International Society for the Study of the Lumbar Spine2007ISSLS Prize for Low Back Pain Research
    Spine2005  - 2017Deputy Editor
    International Society for the Study of the Lumbar Spine2001Medtronic Sofamor Danek Best Poster Award
    Spine Arthroplasty Society2000Norby-Smith Award for Minimally Invasive Surgery
    National Research Council1999Panelist for Musculoskeletal Disorders and the Workplace
    International Society for the Study of the Lumbar Spine1998Volvo Award for Low Back Pain Research
    North American Spine Society1993AcroMed Award for Outstanding Spinal Research

    Collapse Overview 
    Collapse Overview
    Professor Jeffrey Lotz, Ph.D. is the David S. Bradford M.D. Endowed Chair in Orthopaedic Surgery and Vice Chair of Orthopaedic Research at UCSF. He has led the Orthopaedic Tissue Engineering Laboratory at UCSF since 1992, and is the principal investigator of one of the three Mechanistic Research Centers funded through the NIH Back Pain Consortium (BACPAC) Research Program (under NIH HEAL). BACPAC is a translational, patient-centered effort to address the need for effective and personalized therapies for chronic low back pain. Dr. Lotz is also co-director of two other research centers, including the NIDCR-funded Center for Dental, Oral and Craniofacial Tissue and Organ Regeneration (C-DOCTOR, and the NSF-funded Industry/University Cooperative Research Center (CDMI). Dr. Lotz has expertise in spine biomechanics, intervertebral disc biology, and tissue engineering. His laboratory work focuses on identifying mechanisms of disc degeneration, developing novel diagnostics and therapies for low back pain, and the biomechanics of spinal instrumentation. Dr. Lotz earned a doctorate in Medical Engineering from the Harvard/MIT Division of Health Sciences and Technology, a Master's Degree in Mechanical Engineering Design from Stanford University, and a Bachelor of Science in Mechanical Engineering from UC Berkeley.
    Collapse In The News

    Collapse Research 
    Collapse Research Activities and Funding
    Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration (C-DOCTOR)
    NIH U24DE029463May 7, 2020 - Apr 30, 2025
    Role: Co-Principal Investigator
    UCSF Core Center for Patient-centric Mechanistic Phenotyping in Chronic Low Back Pain
    NIH U19AR076737Sep 25, 2019 - May 31, 2024
    Role: Principal Investigator
    Core Center for Musculoskeletal Biology and Medicine (Overall Application)
    NIH P30AR075055Jul 1, 2019 - Jun 30, 2024
    Role: Principal Investigator
    Non-Thermal Pulsed FUS for Treatment of Intervertebral Disc Degeneration
    NIH R21EB024347Apr 1, 2017 - Jan 31, 2020
    Role: Co-Principal Investigator
    Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration (C-DOCTOR)
    NIH U24DE026914Mar 1, 2017 - Feb 28, 2021
    Role: Principal Investigator
    A Clinical 3D Movement Analysis System for Assessing Lower Extremity Injury Risk and Recovery in Athletes
    NIH R41AR068202Sep 1, 2016 - Jan 31, 2018
    Role: Principal Investigator
    University of California Tissue Regeneration Resource Center (UCTRRC)
    NIH R34DE025592Sep 8, 2015 - Aug 31, 2016
    Role: Principal Investigator
    UCSF Core Center for Musculoskeletal Biology and Medicine
    NIH P30AR066262Jul 1, 2014 - Mar 31, 2020
    Role: Principal Investigator
    Phenotypes of pathologic vertebral endplate degeneration
    NIH R56AR063705Aug 1, 2013 - Aug 31, 2020
    Role: Principal Investigator
    Phenotypes of pathologic vertebral endplate degeneration
    NIH R01AR063705Aug 1, 2013 - May 31, 2019
    Role: Principal Investigator
    Structured co-culture of stem cells and chondrocytes for spinal disc repair
    NIH R21AR063357Jul 1, 2012 - Apr 30, 2015
    Role: Principal Investigator
    Endplate permeability and spinal disc degeneration
    NIH R01AR052811Jul 1, 2007 - Jun 30, 2012
    Role: Principal Investigator
    Intervertebral disc repair with Mesenchymal Stem Cells
    NIH R01AR052712Aug 20, 2005 - Jul 31, 2010
    Role: Principal Investigator
    Mesenchymal Stem Cell Differentiation &Mechanoplasticity
    NIH R01AR049786Jul 22, 2004 - Apr 30, 2009
    Role: Principal Investigator
    Structure/function Relationships in Annulus Fibrosus
    NIH R01AR049770Apr 1, 2004 - Jan 31, 2010
    Role: Principal Investigator
    ANALYSIS OF INJURY AVOIDANCE STRATEGIES DURING FALLS
    NIH R01AR046890Sep 20, 2000 - Aug 31, 2004
    Role: Principal Investigator
    TOLERANCE OF THE INTERVERTEBRAL DISC
    NIH R01AR046173Sep 30, 1998 - Aug 31, 2003
    Role: Principal Investigator
    INTERVERTEBRAL DISC INJURY MECHANISMS AND TOLERANCE
    NIH R01AR044179May 1, 1998 - Mar 31, 2002
    Role: Principal Investigator
    UCSF/UCB Joint Graduate Group in Bioengineering
    NIH T32GM008155Jul 1, 1985 - Jun 30, 2021
    Role: Co-Principal Investigator
    MULTIPURPOSE ARTHRITIS AND MUSCULOSKELETAL DISEASES CTR
    NIH P60AR020684Sep 15, 1977 - Dec 31, 2003
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Establishing a Gold Standard for Noninvasive Identification of Painful Lumbar Discs: Prospective Comparison of Magnetic Resonance Spectroscopy vs Low-Pressure Provocation Discography. Int J Spine Surg. 2024 Feb 27. Gornet MG, Peacock J, Ryken T, Schranck FW, Eastlack RK, Lotz JC. PMID: 38413238.
      View in: PubMed   Mentions:
    2. Predictors of response in PROMIS-global in a chronic low back pain specialty clinic: STarTBack and chronic overlapping pain conditions. J Back Musculoskelet Rehabil. 2024 Feb 01. Zheng P, Ewing S, Tang A, Black D, Hue T, Lotz J, Peterson T, Torres-Espin A, O'Neill C. PMID: 38427463.
      View in: PubMed   Mentions:    Fields:    
    3. Preferences for risks and benefits of treatment outcomes for chronic low back pain: Choice-based conjoint measure development and discrete choice experiment. PM R. 2023 Dec 01. Wilson L, Denham A, Ionova Y, O'Neill C, Greco CM, Hassett AL, Hanmer J, Shaikh S, Wolf M, Berven S, Williams D, Ma Y, Lotz J, Zheng P. PMID: 38040670.
      View in: PubMed   Mentions:    Fields:    
    4. An exploration of knowledge-organizing technologies to advance transdisciplinary back pain research. JOR Spine. 2023 Dec; 6(4):e1300. Lotz JC, Ropella G, Anderson P, Yang Q, Hedderich MA, Bailey J, Hunt CA. PMID: 38156063; PMCID: PMC10751978.
      View in: PubMed   Mentions:
    5. Type 2 diabetes impairs annulus fibrosus fiber deformation and rotation under disc compression in the University of California Davis type 2 diabetes mellitus (UCD-T2DM) rat model. PNAS Nexus. 2023 Dec; 2(12):pgad363. Rosenberg JL, Schaible E, Bostrom A, Lazar AA, Graham JL, Stanhope KL, Ritchie RO, Alliston TN, Lotz JC, Havel PJ, Acevedo C, Fields AJ. PMID: 38094616; PMCID: PMC10718642.
      View in: PubMed   Mentions:
    6. Theoretical Schemas to Guide Back Pain Consortium (BACPAC) Chronic Low Back Pain Clinical Research. Pain Med. 2023 08 04; 24(Suppl 1):S13-S35. Chau A, Steib S, Whitaker E, Kohns D, Quinter A, Craig A, Chiodo A, Chandran S, Laidlaw A, Schott Z, Farlow N, Yarjanian J, Omwanghe A, Wasserman R, O'Neill C, Clauw D, Bowden A, Marras W, Carey T, Mehling W, Hunt CA, Lotz J. PMID: 36562563; PMCID: PMC10403312.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. The Back Pain Consortium (BACPAC) Research Program: Structure, Research Priorities, and Methods. Pain Med. 2023 08 04; 24(Suppl 1):S3-S12. Mauck MC, Lotz J, Psioda MA, Carey TS, Clauw DJ, Majumdar S, Marras WS, Vo N, Aylward A, Hoffmeyer A, Zheng P, Ivanova A, McCumber M, Carson C, Anstrom KJ, Bowden AE, Dalton D, Derr L, Dufour J, Fields AJ, Fritz J, Hassett AL, Harte SE, Hue TF, Krug R, Loggia ML, Mageswaran P, McLean SA, Mitchell UH, O'Neill C, Pedoia V, Quirk DA, Rhon DI, Rieke V, Shah L, Sowa G, Spiegel B, Wasan AD, Wey HM, LaVange L. PMID: 36622041; PMCID: PMC10403298.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    8. Magnetic Resonance Imaging of the Lumbar Spine: Recommendations for Acquisition and Image Evaluation from the BACPAC Spine Imaging Working Group. Pain Med. 2023 08 04; 24(Suppl 1):S81-S94. Sollmann N, Fields AJ, O'Neill C, Nardo L, Majumdar S, Chin CT, Tosun D, Han M, Vu AT, Ozhinsky E, Shah LM, Harris RE, Lobo R, Anderst W, Herzog R, Psioda MA, Standaert CJ, Price RT, Lotz JC, Link TM, Krug R. PMID: 36069660; PMCID: PMC10403314.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. CAPER: patient preferences to inform nonsurgical treatment of chronic low back pain: a discrete-choice experiment. Pain Med. 2023 08 01; 24(8):963-973. Wilson L, Zheng P, Ionova Y, Denham A, Yoo C, Ma Y, Greco CM, Hanmer J, Williams DA, Hassett AL, Scheffler AW, Valone F, Mehling W, Berven S, Lotz J, O'Neill C. PMID: 36975607.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Magnetic resonance spectroscopy (MRS) identification of chemically painful lumbar discs leads to improved 6-, 12-, and 24-month outcomes for discogenic low back pain surgeries. Eur Spine J. 2023 06; 32(6):1973-1984. Gornet MF, Eastlack RK, Peacock J, Schranck FW, Lotz JC. PMID: 37014434.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Multi-domain biopsychosocial postoperative recovery trajectories associate with patient outcomes following lumbar fusion. Eur Spine J. 2023 04; 32(4):1429-1436. Halvorson RT, Torres-Espin A, Callahan M, Tay B, O'Neill C, Berven S, Lotz JC, Bailey JF. PMID: 36877367.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Intradiscal treatment of the cartilage endplate for improving solute transport and disc nutrition. Front Bioeng Biotechnol. 2023; 11:1111356. Habib M, Hussien S, Jeon O, Lotz JC, Wu PI, Alsberg E, Fields AJ. PMID: 36923455; PMCID: PMC10008947.
      View in: PubMed   Mentions: 3  
    13. ISSLS Prize in Bioengineering Science 2023: Age- and sex-related differences in lumbar intervertebral disc degeneration between patients with chronic low back pain and asymptomatic controls. Eur Spine J. 2023 05; 32(5):1517-1524. Bonnheim NB, Lazar AA, Kumar A, Akkaya Z, Zhou J, Guo X, O'Neill C, Link TM, Lotz JC, Krug R, Fields AJ. PMID: 36805320; PMCID: PMC10205694.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. The relative influence of model parameters on finite element analysis simulations of intervertebral body fusion device static compression performance. Comput Methods Biomech Biomed Engin. 2023 Oct-Dec; 26(14):1742-1751. Baumann AP, Hsieh MT, Dmitriev AE, Lotz JC. PMID: 36308761.
      View in: PubMed   Mentions: 1     Fields:    
    15. Magnetic Resonance Imaging Characteristics Associated with Treatment Success from Basivertebral Nerve Ablation: An Aggregated Cohort Study of Multicenter Prospective Clinical Trials Data. Pain Med. 2022 07 20; 23(Suppl 2):S34-S49. McCormick ZL, Conger A, Smuck M, Lotz JC, Hirsch JA, Hickman C, Harper K, Burnham TR. PMID: 35856328; PMCID: PMC9297152.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Vertebrogenic Pain: A Paradigm Shift in Diagnosis and Treatment of Axial Low Back Pain. Pain Med. 2022 07 20; 23(Suppl 2):S63-S71. Conger A, Smuck M, Truumees E, Lotz JC, DePalma MJ, McCormick ZL. PMID: 35856329; PMCID: PMC9297155.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    17. Pain Location and Exacerbating Activities Associated with Treatment Success Following Basivertebral Nerve Ablation: An Aggregated Cohort Study of Multicenter Prospective Clinical Trial Data. Pain Med. 2022 07 20; 23(Suppl 2):S14-S33. McCormick ZL, Sperry BP, Boody BS, Hirsch JA, Conger A, Harper K, Lotz JC, Burnham TR. PMID: 35856332; PMCID: PMC9297150.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Influence of patient-specific factors when comparing multifidus fat infiltration between chronic low back pain patients and asymptomatic controls. JOR Spine. 2022 Dec; 5(4):e1217. Ballatori AM, Shahrestani S, Nyayapati P, Agarwal V, Krug R, Han M, Fields AJ, O'Neill C, Demir-Deviren S, Lotz JC, Bailey JF. PMID: 36601370; PMCID: PMC9799081.
      View in: PubMed   Mentions: 1  
    19. Point-of-care motion capture and biomechanical assessment improve clinical utility of dynamic balance testing for lower extremity osteoarthritis. PLOS Digit Health. 2022 Jul; 1(7):e0000068. Halvorson RT, Castillo FT, Ahamed F, Khattab K, Scheffler A, Matthew RP, Lotz J, Vail TP, Feeley BT, Bailey JF. PMID: 36812556; PMCID: PMC9931224.
      View in: PubMed   Mentions:
    20. Spatial distribution of fat infiltration within the paraspinal muscles: implications for chronic low back pain. Eur Spine J. 2022 11; 31(11):2875-2883. Khattab K, Dziesinski LK, Crawford R, Ballatori A, Nyayapati P, Krug R, Fields A, O'Neill CW, Lotz JC, Bailey JF. PMID: 35776179; PMCID: PMC9637053.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. Compensatory biomechanics and spinal loading during dynamic maneuvers in patients with chronic low back pain. Eur Spine J. 2022 07; 31(7):1889-1896. Nyayapati P, Booker J, Wu PI, Theologis A, Dziesinski L, O'Neill C, Zheng P, Lotz JC, Matthew RP, Bailey JF. PMID: 35604457; PMCID: PMC9252943.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. The contributions of cartilage endplate composition and vertebral bone marrow fat to intervertebral disc degeneration in patients with chronic low back pain. Eur Spine J. 2022 07; 31(7):1866-1872. Bonnheim NB, Wang L, Lazar AA, Zhou J, Chachad R, Sollmann N, Guo X, Iriondo C, O'Neill C, Lotz JC, Link TM, Krug R, Fields AJ. PMID: 35441890; PMCID: PMC9252939.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    23. Unsupervised Machine Learning on Motion Capture Data Uncovers Movement Strategies in Low Back Pain. Front Bioeng Biotechnol. 2022; 10:868684. Keller AV, Torres-Espin A, Peterson TA, Booker J, O'Neill C, Lotz JC, Bailey JF, Ferguson AR, Matthew RP. PMID: 35497350; PMCID: PMC9047543.
      View in: PubMed   Mentions:
    24. Using hierarchical unsupervised learning to integrate and reduce multi-level and multi-paraspinal muscle MRI data in relation to low back pain. Eur Spine J. 2022 08; 31(8):2046-2056. Torres-Espin A, Keller A, Johnson GTA, Fields AJ, Krug R, Ferguson AR, Hargens AR, O'Neill CW, Lotz JC, Bailey JF. PMID: 35333958; PMCID: PMC9338899.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Automated assessment and classification of spine, hip, and knee pathologies from sit-to-stand movements collected in clinical practice. J Biomech. 2021 11 09; 128:110786. Girase H, Nyayapati P, Booker J, Lotz JC, Bailey JF, Matthew RP. PMID: 34656825.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. Biomechanical changes in the lumbar spine following spaceflight and factors associated with postspaceflight disc herniation. Spine J. 2022 02; 22(2):197-206. Bailey JF, Nyayapati P, Johnson GTA, Dziesinski L, Scheffler AW, Crawford R, Scheuring R, O'Neill CW, Chang D, Hargens AR, Lotz JC. PMID: 34343665.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    27. A perspective on the ORS Spine Section initiative to develop a multi-species JOR Spine histopathology series. JOR Spine. 2021 Jun; 4(2):e1165. Dahia CL, Engiles JB, Gullbrand SE, Iatridis JC, Lai A, Le Maitre CL, Lotz JC, Masuda K, Séguin CA, Tryfonidou MA. PMID: 34337339; PMCID: PMC8313167.
      View in: PubMed   Mentions: 4  
    28. Development of a standardized histopathology scoring system for human intervertebral disc degeneration: an Orthopaedic Research Society Spine Section Initiative. JOR Spine. 2021 Jun; 4(2):e1167. Le Maitre CL, Dahia CL, Giers M, Illien-Junger S, Cicione C, Samartzis D, Vadala G, Fields A, Lotz J. PMID: 34337340; PMCID: PMC8313169.
      View in: PubMed   Mentions: 17  
    29. Paraspinal muscle degeneration and regenerative potential in a Murine model of Lumbar Disc Injury. N Am Spine Soc J. 2021 Jun; 6:100061. Davies MR, Kaur G, Liu X, Alvarado FG, Nuthalapati P, Liu M, Diaz A, Lotz JC, Bailey JF, Feeley BT. PMID: 35141626; PMCID: PMC8820077.
      View in: PubMed   Mentions: 3  
    30. Pulsed Electromagnetic Fields Accelerate Sensorimotor Recovery Following Experimental Disc Herniation. Spine (Phila Pa 1976). 2021 Feb 15; 46(4):E222-E233. Chan AK, Ballatori A, Nyayapati P, Mummaneni NV, Coughlin D, Liebenberg E, Külling FA, Zhang N, Waldorff EI, Ryaby JT, Lotz JC. PMID: 33475275.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    31. Measurement of vertebral endplate bone marrow lesion (Modic change) composition with water-fat MRI and relationship to patient-reported outcome measures. Eur Spine J. 2021 09; 30(9):2549-2556. Fields AJ, Ballatori A, Han M, Bailey JF, McCormick ZL, O'Neill CW, Demir-Deviren S, Krug R, Lotz JC. PMID: 33547944; PMCID: PMC8697722.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    32. Assessing the use of finite element analysis for mechanical performance evaluation of intervertebral body fusion devices. JOR Spine. 2021 Mar; 4(1):e1137. Baumann AP, Graf T, Peck JH, Dmitriev AE, Coughlan D, Lotz JC. PMID: 33778409; PMCID: PMC7984007.
      View in: PubMed   Mentions: 5  
    33. Serum biomarkers for Modic changes in patients with chronic low back pain. Eur Spine J. 2021 04; 30(4):1018-1027. Karppinen J, Koivisto K, Ketola J, Haapea M, Paananen M, Herzig KH, Alini M, Lotz J, Dudli S, Samartzis D, Risteli J, Majuri ML, Alenius H, Kyllönen E, Järvinen J, Niinimäki J, Grad S. PMID: 33423134.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    34. In silico feasibility assessment of extracorporeal delivery of low-intensity pulsed ultrasound to intervertebral discs within the lumbar spine. Phys Med Biol. 2020 11 05; 65(21):215011. Adams MS, Lotz JC, Diederich CJ. PMID: 32620003.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    35. Reachable Workspace and Proximal Function Measures for Quantifying Upper Limb Motion. IEEE J Biomed Health Inform. 2020 11; 24(11):3285-3294. Matthew RP, Seko S, Kurillo G, Bajcsy R, Cheng L, Han JJ, Lotz J. PMID: 32340969.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    36. FDA public workshop: Orthopaedic sensing, measuring, and advanced reporting technology (SMART) devices. J Orthop Res. 2021 01; 39(1):22-29. Baumann AP, O'Neill C, Owens MC, Weber SC, Sivan S, D'Amico R, Carmody S, Bini S, Sawyer AJ, Lotz JC, Goel V, Dmitriev AE. PMID: 32827329.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    37. Magnetic Nanoparticles Synergize with Pulsed Magnetic Fields to Stimulate Osteogenesis In Vitro. Tissue Eng Part A. 2021 03; 27(5-6):402-412. Habib M, Horne DA, Hussein K, Coughlin D, Waldorff EI, Zhang N, Ryaby JT, Lotz JC. PMID: 32746770.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    38. Automatic Vertebral Body Segmentation Based on Deep Learning of Dixon Images for Bone Marrow Fat Fraction Quantification. Front Endocrinol (Lausanne). 2020; 11:612. Zhou J, Damasceno PF, Chachad R, Cheung JR, Ballatori A, Lotz JC, Lazar AA, Link TM, Fields AJ, Krug R. PMID: 32982989; PMCID: PMC7492292.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    39. Serum Biomarkers for Connective Tissue and Basement Membrane Remodeling are Associated with Vertebral Endplate Bone Marrow Lesions as Seen on MRI (Modic Changes). Int J Mol Sci. 2020 May 27; 21(11). Dudli S, Ballatori A, Bay-Jensen AC, McCormick ZL, O'Neill CW, Demir-Deviren S, Krug R, Heggli I, Juengel A, Karppinen J, Brunner F, Farshad M, Distler O, Lotz JC, Fields AJ. PMID: 32471173; PMCID: PMC7312719.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    40. LIPUS far-field exposimetry system for uniform stimulation of tissues in-vitro: development and validation with bovine intervertebral disc cells. Biomed Phys Eng Express. 2020 05 06; 6(3):035033. Horne DA, Jones PD, Adams MS, Lotz JC, Diederich CJ. PMID: 33438678.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    41. The Effect of Parity on Age-Related Degenerative Changes in Sagittal Balance. Spine (Phila Pa 1976). 2020 Feb 15; 45(4):E210-E216. Bailey JF, Sparrey CJ, Williams FMK, Curran PF, Lotz JC, Kramer PA. PMID: 31513113.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    42. The Effect of Zoledronic Acid on Serum Biomarkers among Patients with Chronic Low Back Pain and Modic Changes in Lumbar Magnetic Resonance Imaging. Diagnostics (Basel). 2019 Dec 04; 9(4). Koivisto K, Karppinen J, Haapea M, Järvinen J, Kyllönen E, Tervonen O, Niinimäki J, Alini M, Lotz J, Dudli S, Samartzis D, Risteli J, Majuri ML, Alenius H, Grad S. PMID: 31817123; PMCID: PMC6963270.
      View in: PubMed   Mentions: 5  
    43. Pulsed electromagnetic fields reduce acute inflammation in the injured rat-tail intervertebral disc. JOR Spine. 2019 Dec; 2(4):e1069. Chan AK, Tang X, Mummaneni NV, Coughlin D, Liebenberg E, Ouyang A, Dudli S, Lauricella M, Zhang N, Waldorff EI, Ryaby JT, Lotz JC. PMID: 31891118; PMCID: PMC6920683.
      View in: PubMed   Mentions: 12  
    44. Pulsed Electromagnetic Fields Reduce Interleukin-6 Expression in Intervertebral Disc Cells Via Nuclear Factor-κβ and Mitogen-Activated Protein Kinase p38 Pathways. Spine (Phila Pa 1976). 2019 Nov 15; 44(22):E1290-E1297. Tang X, Coughlin D, Ballatori A, Berg-Johansen B, Waldorff EI, Zhang N, Ryaby JT, Aliston T, Lotz JC. PMID: 31689248.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    45. Osteocyte dysfunction promotes osteoarthritis through MMP13-dependent suppression of subchondral bone homeostasis. Bone Res. 2019; 7:34. Mazur CM, Woo JJ, Yee CS, Fields AJ, Acevedo C, Bailey KN, Kaya S, Fowler TW, Lotz JC, Dang A, Kuo AC, Vail TP, Alliston T. PMID: 31700695; PMCID: PMC6828661.
      View in: PubMed   Mentions: 41  
    46. Measuring and reporting of vertebral endplate bone marrow lesions as seen on MRI (Modic changes): recommendations from the ISSLS Degenerative Spinal Phenotypes Group. Eur Spine J. 2019 10; 28(10):2266-2274. Fields AJ, Battié MC, Herzog RJ, Jarvik JG, Krug R, Link TM, Lotz JC, O'Neill CW, Sharma A, ISSLS Degenerative Spinal Phenotypes Group. PMID: 31446492; PMCID: PMC7205555.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    47. The Relationship Between Endplate Pathology and Patient-reported Symptoms for Chronic Low Back Pain Depends on Lumbar Paraspinal Muscle Quality. Spine (Phila Pa 1976). 2019 Jul 15; 44(14):1010-1017. Bailey JF, Fields AJ, Ballatori A, Cohen D, Jain D, Coughlin D, O'Neill C, McCormick Z, Han M, Krug R, Demir-Deviren S, Lotz JC. PMID: 30896590; PMCID: PMC6597281.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    48. Functional workspace and patient-reported outcomes improve after reverse and total shoulder arthroplasty. J Shoulder Elbow Surg. 2019 Nov; 28(11):2121-2127. Ngan A, Xiao W, Curran PF, Tseng WJ, Hung LW, Nguyen C, Matthew R, Ma B, Lotz J, Feeley BT. PMID: 31281000.
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    49. Simple Spline Representation for Identifying Sit-to-Stand Strategies. Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul; 2019:4097-4103. Matthew RP, Seko S, Bailey J, Bajcsy R, Lotz J. PMID: 31946772.
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    50. Matrix modification for enhancing the transport properties of the human cartilage endplate to improve disc nutrition. PLoS One. 2019; 14(4):e0215218. Dolor A, Sampson SL, Lazar AA, Lotz JC, Szoka FC, Fields AJ. PMID: 30970007; PMCID: PMC6457523.
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    51. ISSLS PRIZE IN BIOENGINEERING SCIENCE 2019: biomechanical changes in dynamic sagittal balance and lower limb compensatory strategies following realignment surgery in adult spinal deformity patients. Eur Spine J. 2019 05; 28(5):905-913. Bailey JF, Matthew RP, Seko S, Curran P, Chu L, Berven SH, Deviren V, Burch S, Lotz JC. PMID: 30826876; PMCID: PMC6536471.
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    52. Estimating Sit-to-Stand Dynamics Using a Single Depth Camera. IEEE J Biomed Health Inform. 2019 11; 23(6):2592-2602. Matthew RP, Seko S, Bailey J, Bajcsy R, Lotz J. PMID: 30716057.
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    53. Nutrient supply and nucleus pulposus cell function: effects of the transport properties of the cartilage endplate and potential implications for intradiscal biologic therapy. Osteoarthritis Cartilage. 2019 06; 27(6):956-964. Wong J, Sampson SL, Bell-Briones H, Ouyang A, Lazar AA, Lotz JC, Fields AJ. PMID: 30721733; PMCID: PMC6536352.
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    54. Associations between vertebral body fat fraction and intervertebral disc biochemical composition as assessed by quantitative MRI. J Magn Reson Imaging. 2019 10; 50(4):1219-1226. Krug R, Joseph GB, Han M, Fields A, Cheung J, Mundada M, Bailey J, Rochette A, Ballatori A, McCulloch CE, McCormick Z, O'Neill C, Link TM, Lotz J. PMID: 30701594; PMCID: PMC6667309.
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    55. Magnetic resonance spectroscopy (MRS) can identify painful lumbar discs and may facilitate improved clinical outcomes of lumbar surgeries for discogenic pain. Eur Spine J. 2019 04; 28(4):674-687. Gornet MG, Peacock J, Claude J, Schranck FW, Copay AG, Eastlack RK, Benz R, Olshen A, Lotz JC. PMID: 30610465.
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    56. Advancing cell therapies for intervertebral disc regeneration from the lab to the clinic: Recommendations of the ORS spine section. JOR Spine. 2018 Dec; 1(4):e1036. Smith LJ, Silverman L, Sakai D, Le Maitre CL, Mauck RL, Malhotra NR, Lotz JC, Buckley CT. PMID: 30895277; PMCID: PMC6419951.
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    57. Kinematic and Kinetic Validation of an Improved Depth Camera Motion Assessment System Using Rigid Bodies. IEEE J Biomed Health Inform. 2019 07; 23(4):1784-1793. Matthew RP, Seko S, Bajcsy R, Lotz J. PMID: 30281504.
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    58. Contribution of the endplates to disc degeneration. Curr Mol Biol Rep. 2018 Dec; 4(4):151-160. Fields AJ, Ballatori A, Liebenberg EC, Lotz JC. PMID: 30546999; PMCID: PMC6287619.
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    59. Tidemark Avulsions are a Predominant Form of Endplate Irregularity. Spine (Phila Pa 1976). 2018 08; 43(16):1095-1101. Berg-Johansen B, Jain D, Liebenberg EC, Fields AJ, Link TM, O'Neill CW, Lotz JC. PMID: 29315127; PMCID: PMC6035893.
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    60. Tracking Kinematic and Kinetic Measures of Sit to Stand using an Instrumented Spine Orthosis. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul; 2018:1-5. Matthew RP, Seko S, Bailey J, Bajcsy R, Lotz J. PMID: 30440257; PMCID: PMC6438185.
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    61. A functional method for generating individualized spine models from motion-capture data. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul; 2018:1-5. Seko S, Matthew RP, Bajcsy R, Lotz JC. PMID: 30440263.
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    62. Quantification of Propionic Acid in the Bovine Spinal Disk After Infection of the Tissue With Propionibacteria acnes Bacteria. Spine (Phila Pa 1976). 2018 06 01; 43(11):E634-E638. Magnitsky S, Dudli S, Tang X, Kaur J, Diaz J, Miller S, Lotz JC. PMID: 29019804; PMCID: PMC5893447.
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    63. Cartilage Endplate Thickness Variation Measured by Ultrashort Echo-Time MRI Is Associated With Adjacent Disc Degeneration. Spine (Phila Pa 1976). 2018 05 15; 43(10):E592-E600. Berg-Johansen B, Han M, Fields AJ, Liebenberg EC, Lim BJ, Larson PE, Gunduz-Demir C, Kazakia GJ, Krug R, Lotz JC. PMID: 28984733; PMCID: PMC5882595.
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    64. Dental, Oral, and Craniofacial Regenerative Medicine: Transforming Biotechnologies for Innovating Patient Care. J Dent Res. 2018 04; 97(4):361-363. Giannobile WV, Chai Y, Chen Y, Healy KE, Klein O, Lane N, Longaker MT, Lotz JC, Mooney DJ, Sfeir CS, Urata M, Wagner WR, Wu BM, Kohn DH. PMID: 29557734; PMCID: PMC5863875.
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    65. Modic type 1 change is an autoimmune response that requires a proinflammatory milieu provided by the 'Modic disc'. Spine J. 2018 05; 18(5):831-844. Dudli S, Liebenberg E, Magnitsky S, Lu B, Lauricella M, Lotz JC. PMID: 29253635.
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    66. Dynamic imaging demonstrates that pulsed electromagnetic fields (PEMF) suppress IL-6 transcription in bovine nucleus pulposus cells. J Orthop Res. 2018 02; 36(2):778-787. Tang X, Alliston T, Coughlin D, Miller S, Zhang N, Waldorff EI, Ryaby JT, Lotz JC. PMID: 28851112; PMCID: PMC5873378.
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    67. From the international space station to the clinic: how prolonged unloading may disrupt lumbar spine stability. Spine J. 2018 01; 18(1):7-14. Bailey JF, Miller SL, Khieu K, O'Neill CW, Healey RM, Coughlin DG, Sayson JV, Chang DG, Hargens AR, Lotz JC. PMID: 28962911; PMCID: PMC6339989.
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    68. Structural vertebral endplate nomenclature and etiology: a study by the ISSLS Spinal Phenotype Focus Group. Eur Spine J. 2018 01; 27(1):2-12. Zehra U, Bow C, Lotz JC, Williams FMK, Rajasekaran S, Karppinen J, Luk KDK, C Battiê M, Samartzis D. PMID: 28900744.
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    69. Inflammatory response of disc cells against Propionibacterium acnes depends on the presence of lumbar Modic changes. Eur Spine J. 2018 05; 27(5):1013-1020. Dudli S, Miller S, Demir-Deviren S, Lotz JC. PMID: 28884220; PMCID: PMC5842102.
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    70. A Kinect-based movement assessment system: marker position comparison to Vicon. Comput Methods Biomech Biomed Engin. 2017 Sep; 20(12):1289-1298. Nichols JK, Sena MP, Hu JL, O'Reilly OM, Feeley BT, Lotz JC. PMID: 28699356.
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    71. Structure-function relationships at the human spinal disc-vertebra interface. J Orthop Res. 2018 01; 36(1):192-201. Berg-Johansen B, Fields AJ, Liebenberg EC, Li A, Lotz JC. PMID: 28590060; PMCID: PMC5720932.
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    72. Role of Osteoblast Gi Signaling in Age-Related Bone Loss in Female Mice. Endocrinology. 2017 06 01; 158(6):1715-1726. Millard SM, Wang L, Wattanachanya L, O'Carroll D, Fields AJ, Pang J, Kazakia G, Lotz JC, Nissenson RA. PMID: 28407060; PMCID: PMC5460929.
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    73. Glucocorticoid suppression of osteocyte perilacunar remodeling is associated with subchondral bone degeneration in osteonecrosis. Sci Rep. 2017 03 22; 7:44618. Fowler TW, Acevedo C, Mazur CM, Hall-Glenn F, Fields AJ, Bale HA, Ritchie RO, Lotz JC, Vail TP, Alliston T. PMID: 28327602; PMCID: PMC5361115.
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    74. Low intensity pulsed ultrasound (LIPUS) for the treatment of intervertebral disc degeneration. Proc SPIE Int Soc Opt Eng. 2017 Jan-Feb; 10066. Horne D, Jones P, Salgaonkar V, Adams M, Ozilgen BA, Zahos P, Tang X, Liebenburg E, Coughlin D, Lotz J, Diederich C. PMID: 29104343; PMCID: PMC5667559.
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    75. Mechanical performance of cervical intervertebral body fusion devices: A systematic analysis of data submitted to the Food and Drug Administration. J Biomech. 2017 03 21; 54:26-32. Peck JH, Sing DC, Nagaraja S, Peck DG, Lotz JC, Dmitriev AE. PMID: 28256243.
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    76. ISSLS PRIZE IN BASIC SCIENCE 2017: Intervertebral disc/bone marrow cross-talk with Modic changes. Eur Spine J. 2017 05; 26(5):1362-1373. Dudli S, Sing DC, Hu SS, Berven SH, Burch S, Deviren V, Cheng I, Tay BKB, Alamin TF, Ith MAM, Pietras EM, Lotz JC. PMID: 28138783; PMCID: PMC5409869.
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    77. Lumbar Spine Paraspinal Muscle and Intervertebral Disc Height Changes in Astronauts After Long-Duration Spaceflight on the International Space Station. Spine (Phila Pa 1976). 2016 Dec 15; 41(24):1917-1924. Chang DG, Healey RM, Snyder AJ, Sayson JV, Macias BR, Coughlin DG, Bailey JF, Parazynski SE, Lotz JC, Hargens AR. PMID: 27779600; PMCID: PMC5588025.
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    78. Effects of cell type and configuration on anabolic and catabolic activity in 3D co-culture of mesenchymal stem cells and nucleus pulposus cells. J Orthop Res. 2017 01; 35(1):61-73. Ouyang A, Cerchiari AE, Tang X, Liebenberg E, Alliston T, Gartner ZJ, Lotz JC. PMID: 27699833; PMCID: PMC5258652.
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    79. Propionibacterium acnes infected intervertebral discs cause vertebral bone marrow lesions consistent with Modic changes. J Orthop Res. 2016 08; 34(8):1447-55. Dudli S, Liebenberg E, Magnitsky S, Miller S, Demir-Deviren S, Lotz JC. PMID: 27101067.
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    80. Implantation of juvenile human chondrocytes demonstrates no adverse effect on spinal nerve tissue in rats. Eur Spine J. 2016 09; 25(9):2958-66. Külling FA, Liu JJ, Liebenberg E, Lotz JC. PMID: 27170114.
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    81. Pathobiology of Modic changes. Eur Spine J. 2016 11; 25(11):3723-3734. Dudli S, Fields AJ, Samartzis D, Karppinen J, Lotz JC. PMID: 26914098; PMCID: PMC5477843.
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    82. Pulsed electromagnetic field (PEMF) treatment reduces expression of genes associated with disc degeneration in human intervertebral disc cells. Spine J. 2016 06; 16(6):770-6. Miller SL, Coughlin DG, Waldorff EI, Ryaby JT, Lotz JC. PMID: 26780754.
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    83. The effect of simulated microgravity on lumbar spine biomechanics: an in vitro study. Eur Spine J. 2016 09; 25(9):2889-97. Laws CJ, Berg-Johansen B, Hargens AR, Lotz JC. PMID: 26403291; PMCID: PMC4808488.
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    84. A mechanical pivot-shift device for continuously applying defined loads to cadaveric knees. Knee Surg Sports Traumatol Arthrosc. 2015 Oct; 23(10):2900-8. Sena MP, DellaMaggioria R, Lotz JC, Feeley BT. PMID: 26359176.
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    85. Novel diagnostic and prognostic methods for disc degeneration and low back pain. Spine J. 2015 Sep 01; 15(9):1919-32. Samartzis D, Borthakur A, Belfer I, Bow C, Lotz JC, Wang HQ, Cheung KM, Carragee E, Karppinen J. PMID: 26303178; PMCID: PMC5473425.
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    86. Spaceflight-induced bone loss alters failure mode and reduces bending strength in murine spinal segments. J Orthop Res. 2016 Jan; 34(1):48-57. Berg-Johansen B, Liebenberg EC, Li A, Macias BR, Hargens AR, Lotz JC. PMID: 26285046; PMCID: PMC5477841.
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    87. Cardiovascular magnetic resonance feature-tracking assessment of myocardial mechanics: Intervendor agreement and considerations regarding reproducibility. Clin Radiol. 2015 Sep; 70(9):989-98. Schuster A, Stahnke VC, Unterberg-Buchwald C, Kowallick JT, Lamata P, Steinmetz M, Kutty S, Fasshauer M, Staab W, Sohns JM, Bigalke B, Ritter C, Hasenfuß G, Beerbaum P, Lotz J. PMID: 26139384; PMCID: PMC4683162.
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    88. Neural innervation patterns in the sacral vertebral body. Eur Spine J. 2016 06; 25(6):1932-8. Degmetich S, Bailey JF, Liebenberg E, Lotz JC. PMID: 26077098; PMCID: PMC4681698.
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    89. Tibiofemoral contact pressures in radial tears of the meniscus treated with all-inside repair, inside-out repair and partial meniscectomy. Knee. 2015 Oct; 22(5):400-4. Zhang AL, Miller SL, Coughlin DG, Lotz JC, Feeley BT. PMID: 26081591.
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    90. Osteoclast activators are elevated in intervertebral disks with Modic changes among patients operated for herniated nucleus pulposus. Eur Spine J. 2016 Jan; 25(1):207-216. Torkki M, Majuri ML, Wolff H, Koskelainen T, Haapea M, Niinimäki J, Alenius H, Lotz J, Karppinen J. PMID: 25813008.
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    91. Alterations in intervertebral disc composition, matrix homeostasis and biomechanical behavior in the UCD-T2DM rat model of type 2 diabetes. J Orthop Res. 2015 May; 33(5):738-46. Fields AJ, Berg-Johansen B, Metz LN, Miller S, La B, Liebenberg EC, Coughlin DG, Graham JL, Stanhope KL, Havel PJ, Lotz JC. PMID: 25641259; PMCID: PMC4408867.
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    92. Cartilaginous end plates: Quantitative MR imaging with very short echo times-orientation dependence and correlation with biochemical composition. Radiology. 2015 Feb; 274(2):482-9. Fields AJ, Han M, Krug R, Lotz JC. PMID: 25302832; PMCID: PMC4314292.
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    93. Drug-induced changes to the vertebral endplate vasculature affect transport into the intervertebral disc in vivo. J Orthop Res. 2014 Dec; 32(12):1694-700. Gullbrand SE, Peterson J, Mastropolo R, Lawrence JP, Lopes L, Lotz J, Ledet EH. PMID: 25185989.
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    94. Real-time phase-contrast flow MRI of the ascending aorta and superior vena cava as a function of intrathoracic pressure (Valsalva manoeuvre). Br J Radiol. 2014 Oct; 87(1042):20140401. Kowallick JT, Joseph AA, Unterberg-Buchwald C, Fasshauer M, van Wijk K, Merboldt KD, Voit D, Frahm J, Lotz J, Sohns JM. PMID: 25074791; PMCID: PMC4170873.
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    95. Effect of microgravity on the biomechanical properties of lumbar and caudal intervertebral discs in mice. J Biomech. 2014 Sep 22; 47(12):2983-8. Bailey JF, Hargens AR, Cheng KK, Lotz JC. PMID: 25085756.
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    96. Comparison of vertebral and intervertebral disc lesions in aging humans and rhesus monkeys. Osteoarthritis Cartilage. 2014 Jul; 22(7):980-5. Bailey JF, Fields AJ, Liebenberg E, Mattison JA, Lotz JC, Kramer PA. PMID: 24821664; PMCID: PMC4105267.
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    97. The anabolic effect of plasma-mediated ablation on the intervertebral disc: stimulation of proteoglycan and interleukin-8 production. Spine J. 2014 Oct 01; 14(10):2479-87. Kuelling FA, Foley KT, Liu JJ, Liebenberg E, Sin AH, Matsukawa A, Lotz JC. PMID: 24747799.
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    98. Influence of biochemical composition on endplate cartilage tensile properties in the human lumbar spine. J Orthop Res. 2014 Feb; 32(2):245-52. Fields AJ, Rodriguez D, Gary KN, Liebenberg EC, Lotz JC. PMID: 24273192; PMCID: PMC4039641.
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    99. Intervertebral discs from spinal nondeformity and deformity patients have different mechanical and matrix properties. Spine J. 2014 Mar 01; 14(3):522-30. Cheng KK, Berven SH, Hu SS, Lotz JC. PMID: 24246750; PMCID: PMC3944996.
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    100. On representations for joint moments using a joint coordinate system. J Biomech Eng. 2013 Nov; 135(11):114504. O'Reilly OM, Sena MP, Feeley BT, Lotz JC. PMID: 24008987.
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    102. Disk degeneration and low back pain: are they fat-related conditions? Global Spine J. 2013 Jun; 3(3):133-44. Samartzis D, Karppinen J, Cheung JP, Lotz J. PMID: 24436864; PMCID: PMC3854598.
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    105. Seeing double: a comparison of microstructure, biomechanical function, and adjacent disc health between double- and single-layer vertebral endplates. Spine (Phila Pa 1976). 2012 Oct 01; 37(21):E1310-7. Fields AJ, Sahli F, Rodriguez AG, Lotz JC. PMID: 22781006; PMCID: PMC3461110.
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    106. New treatments and imaging strategies in degenerative disease of the intervertebral disks. Radiology. 2012 Jul; 264(1):6-19. Lotz JC, Haughton V, Boden SD, An HS, Kang JD, Masuda K, Freemont A, Berven S, Sengupta DK, Tanenbaum L, Maurer P, Ranganathan A, Alavi A, Marinelli NL. PMID: 22723559.
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    108. Structured bilaminar coculture outperforms stem cells and disc cells in a simulated degenerate disc environment. Spine (Phila Pa 1976). 2012 May 01; 37(10):813-8. Allon AA, Butcher K, Schneider RA, Lotz JC. PMID: 22024902; PMCID: PMC3340449.
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    112. Biological and biomechanical effects of fibrin injection into porcine intervertebral discs. Spine (Phila Pa 1976). 2011 Aug 15; 36(18):E1201-9. Buser Z, Kuelling F, Liu J, Liebenberg E, Thorne KJ, Coughlin D, Lotz JC. PMID: 21325992.
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    114. Structured three-dimensional co-culture of mesenchymal stem cells with chondrocytes promotes chondrogenic differentiation without hypertrophy. Osteoarthritis Cartilage. 2011 Oct; 19(10):1210-8. Cooke ME, Allon AA, Cheng T, Kuo AC, Kim HT, Vail TP, Marcucio RS, Schneider RA, Lotz JC, Alliston T. PMID: 21816228; PMCID: PMC3188316.
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    116. A musculoskeletal model for the lumbar spine. Biomech Model Mechanobiol. 2012 Jan; 11(1-2):19-34. Christophy M, Faruk Senan NA, Lotz JC, O'Reilly OM. PMID: 21318374.
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    117. Biomechanical evaluation of pediatric anterior cruciate ligament reconstruction techniques. Am J Sports Med. 2011 May; 39(5):964-71. Kennedy A, Coughlin DG, Metzger MF, Tang R, Pearle AD, Lotz JC, Feeley BT. PMID: 21257848.
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    118. Innervation patterns of PGP 9.5-positive nerve fibers within the human lumbar vertebra. J Anat. 2011 Mar; 218(3):263-70. Bailey JF, Liebenberg E, Degmetich S, Lotz JC. PMID: 21223256; PMCID: PMC3058212.
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    119. Load and the spine. How does the Goldilocks principle apply? Spine J. 2011 Jan; 11(1):44-5. Lotz JC. PMID: 21168097.
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    120. [An introduction to the cardiac and vascular diagnostics team]. Rofo. 2010 Nov; 182(11):943-6. Miller S, Gutberlet M, Lotz J, Fischbach R, Barkhausen J. PMID: 21031323.
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    121. Structured coculture of stem cells and disc cells prevent disc degeneration in a rat model. Spine J. 2010 Dec; 10(12):1089-97. Allon AA, Aurouer N, Yoo BB, Liebenberg EC, Buser Z, Lotz JC. PMID: 20971687; PMCID: PMC2991542.
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    122. Minimizing errors associated with calculating the location of the helical axis for spinal motions. J Biomech. 2010 Oct 19; 43(14):2822-9. Metzger MF, Faruk Senan NA, O'Reilly OM, Lotz JC. PMID: 20969997.
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    123. Antithrombogenic modification of small-diameter microfibrous vascular grafts. Arterioscler Thromb Vasc Biol. 2010 Aug; 30(8):1621-7. Hashi CK, Derugin N, Janairo RR, Lee R, Schultz D, Lotz J, Li S. PMID: 20466974; PMCID: PMC2904868.
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    124. Pure moment testing for spinal biomechanics applications: Fixed versus sliding ring cable-driven test designs. J Biomech. 2010 May 07; 43(7):1422-5. Eguizabal J, Tufaga M, Scheer JK, Ames C, Lotz JC, Buckley JM. PMID: 20181340.
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    125. New challenges for intervertebral disc treatment using regenerative medicine. Tissue Eng Part B Rev. 2010 Feb; 16(1):147-58. Masuda K, Lotz JC. PMID: 19903086; PMCID: PMC2817669.
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    126. Trials of vertebroplasty for vertebral fractures. N Engl J Med. 2009 Nov 19; 361(21):2098; author reply 2099-100. Lotz JC. PMID: 19938315.
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    127. On the stiffness matrix of the intervertebral joint: application to total disk replacement. J Biomech Eng. 2009 Aug; 131(8):081007. O'Reilly OM, Metzger MF, Buckley JM, Moody DA, Lotz JC. PMID: 19604019.
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    128. [Recommendations for utilizing computerized tomography and magnetic resonance tomography in heart diagnosis. 2--Magnetic resonance tomography ]. Rofo. 2009 Aug; 181(8):800-14. Lotz J, Kivelitz D, Fischbach R, Beer M, Miller S. PMID: 19621277.
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    129. The influence of ferucarbotran on the chondrogenesis of human mesenchymal stem cells. Contrast Media Mol Imaging. 2009 Jul-Aug; 4(4):165-73. Henning TD, Sutton EJ, Kim A, Golovko D, Horvai A, Ackerman L, Sennino B, McDonald D, Lotz J, Daldrup-Link HE. PMID: 19670250; PMCID: PMC2933782.
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    130. [Recommendations of the Heart Diagnosis Working Group of the German Roentgen Society for use of computerized tomography and magnetic resonance tomography in heart diagnosis. 1-- Computerized tomography]. Rofo. 2009 Jul; 181(7):700-6. Fischbach R, Miller S, Beer M, Lotz J, Kivelitz D. PMID: 19554489.
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    131. Co-culture of Adult Mesenchymal Stem Cells and Nucleus Pulposus Cells in Bilaminar Pellets for Intervertebral Disc Regeneration. SAS J. 2009; 3(2):41-9. Allon AA, Schneider RA, Lotz JC. PMID: 25802627; PMCID: PMC4365592.
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    132. The tissue diagnostic instrument. Rev Sci Instrum. 2009 May; 80(5):054303. Hansma P, Yu H, Schultz D, Rodriguez A, Yurtsev EA, Orr J, Tang S, Miller J, Wallace J, Zok F, Li C, Souza R, Proctor A, Brimer D, Nogues-Solan X, Mellbovsky L, Peña MJ, Diez-Ferrer O, Mathews P, Randall C, Kuo A, Chen C, Peters M, Kohn D, Buckley J, Li X, Pruitt L, Diez-Perez A, Alliston T, Weaver V, Lotz J. PMID: 19485522; PMCID: PMC2832056.
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    133. Mechanical profiling of intervertebral discs. J Biomech. 2009 May 29; 42(8):1154-7. Schultz DS, Rodriguez AG, Hansma PK, Lotz JC. PMID: 19345361; PMCID: PMC3004015.
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    134. Multiple differentiation capacity of STRO-1+/CD146+ PDL mesenchymal progenitor cells. Stem Cells Dev. 2009 Apr; 18(3):487-96. Xu J, Wang W, Kapila Y, Lotz J, Kapila S. PMID: 18593336; PMCID: PMC2702120.
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    135. Pressure and distortion regulate human mesenchymal stem cell gene expression. Ann Biomed Eng. 2009 Mar; 37(3):492-502. Haudenschild AK, Hsieh AH, Kapila S, Lotz JC. PMID: 19125331.
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    136. Biomechanical pullout strength and stability of the cervical artificial pedicle screw. Spine (Phila Pa 1976). 2009 Jan 01; 34(1):E16-20. Barnes AH, Eguizabal JA, Acosta FL, Lotz JC, Buckley JM, Ames CP. PMID: 19127143.
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    137. Quantifying the contributions of structure to the annulus fibrosus mechanical function using a nonlinear, anisotropic, hyperelastic model. J Orthop Res. 2008 Dec; 26(12):1675; author reply 1675-6. Wagner DR, Lotz JC. PMID: 18546190.
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    138. Detection of postoperative granulation tissue with an ICG-enhanced integrated OI-/X-ray System. J Transl Med. 2008 Nov 27; 6:73. Meier R, Boddington S, Krug C, Acosta FL, Thullier D, Henning TD, Sutton EJ, Tavri S, Lotz JC, Daldrup-Link HE. PMID: 19038047; PMCID: PMC2613387.
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    139. Anulus fibrosus tension inhibits degenerative structural changes in lamellar collagen. Eur Spine J. 2008 Sep; 17(9):1149-59. Lotz JC, Hadi T, Bratton C, Reiser KM, Hsieh AH. PMID: 18668268; PMCID: PMC2527408.
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    140. Structural factors that mediate scleral stiffness. Invest Ophthalmol Vis Sci. 2008 Oct; 49(10):4232-6. Schultz DS, Lotz JC, Lee SM, Trinidad ML, Stewart JM. PMID: 18539943.
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    141. Chondrogenic differentiation of human mesenchymal stem cells in three-dimensional alginate gels. Tissue Eng Part A. 2008 May; 14(5):667-80. Xu J, Wang W, Ludeman M, Cheng K, Hayami T, Lotz JC, Kapila S. PMID: 18377198.
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    142. Biomechanical comparison of three fixation techniques for unstable thoracolumbar burst fractures. Laboratory investigation. J Neurosurg Spine. 2008 Apr; 8(4):341-6. Acosta FL, Buckley JM, Xu Z, Lotz JC, Ames CP. PMID: 18377319.
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    143. Lactic acid and proteoglycans as metabolic markers for discogenic back pain. Spine (Phila Pa 1976). 2008 Feb 01; 33(3):312-7. Keshari KR, Lotz JC, Link TM, Hu S, Majumdar S, Kurhanewicz J. PMID: 18303465.
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    144. ISSLS prize winner: repeated disc injury causes persistent inflammation. Spine (Phila Pa 1976). 2007 Dec 01; 32(25):2812-9. Ulrich JA, Liebenberg EC, Thuillier DU, Lotz JC. PMID: 18246002.
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    145. Role of matrix metalloproteinase 13 in both endochondral and intramembranous ossification during skeletal regeneration. PLoS One. 2007 Nov 07; 2(11):e1150. Behonick DJ, Xing Z, Lieu S, Buckley JM, Lotz JC, Marcucio RS, Werb Z, Miclau T, Colnot C. PMID: 17987127; PMCID: PMC2063465.
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    146. Quantitative analysis of structural disorder in intervertebral disks using second harmonic generation imaging: comparison with morphometric analysis. J Biomed Opt. 2007 Nov-Dec; 12(6):064019. Reiser KM, Bratton C, Yankelevich DR, Knoesen A, Rocha-Mendoza I, Lotz J. PMID: 18163835.
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    147. Biological and mechanical consequences of transient intervertebral disc bending. Eur Spine J. 2007 Nov; 16(11):1899-906. Court C, Chin JR, Liebenberg E, Colliou OK, Lotz JC. PMID: 17701429; PMCID: PMC2223345.
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    148. Relationship between femoral head size and distance to lesser trochanter. Clin Orthop Relat Res. 2007 Aug; 461:122-4. Sproul RC, Reynolds HM, Lotz JC, Ries MD. PMID: 17414164.
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    149. In vitro system for applying cyclic loads to connective tissues under displacement or force control. Ann Biomed Eng. 2007 Jul; 35(7):1188-95. Asundi KR, Kursa K, Lotz J, Rempel DM. PMID: 17385043.
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    150. Intradiscal thermal therapy using interstitial ultrasound: an in vivo investigation in ovine cervical spine. Spine (Phila Pa 1976). 2007 Mar 01; 32(5):503-11. Nau WH, Diederich CJ, Shu R, Kinsey A, Bass E, Lotz J, Hu S, Simko J, Ferrier W, Sutton J, Attawia M, Pellegrino R. PMID: 17334283.
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    151. The short-term effects of electrosurgical ablation on proinflammatory mediator production by intervertebral disc cells in tissue culture. Spine J. 2007 Jul-Aug; 7(4):451-8. Rhyu KW, Walsh AJ, O'Neill CW, Bradford DS, Lotz JC. PMID: 17630143.
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    152. Glucosamine HCl alters production of inflammatory mediators by rat intervertebral disc cells in vitro. Spine J. 2007 Sep-Oct; 7(5):601-8. Walsh AJ, O'neill CW, Lotz JC. PMID: 17905323.
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    153. Stab incision for inducing intervertebral disc degeneration in the rat. Spine (Phila Pa 1976). 2007 Jan 01; 32(1):17-24. Rousseau MA, Ulrich JA, Bass EC, Rodriguez AG, Liu JJ, Lotz JC. PMID: 17202887.
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    154. Innervation, inflammation, and hypermobility may characterize pathologic disc degeneration: review of animal model data. J Bone Joint Surg Am. 2006 Apr; 88 Suppl 2:76-82. Lotz JC, Ulrich JA. PMID: 16595449.
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    155. Intradiscal thermal therapy does not stimulate biologic remodeling in an in vivo sheep model. Spine (Phila Pa 1976). 2006 Jan 15; 31(2):139-45. Bass EC, Nau WH, Diederich CJ, Liebenberg E, Shu R, Pellegrino R, Sutton J, Attawia M, Hu SS, Ferrier WT, Lotz JC. PMID: 16418631.
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    156. Glycation increases human annulus fibrosus stiffness in both experimental measurements and theoretical predictions. J Biomech. 2006; 39(6):1021-9. Wagner DR, Reiser KM, Lotz JC. PMID: 15878594.
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    157. Correlation of HR-MAS spectroscopy derived metabolite concentrations with collagen and proteoglycan levels and Thompson grade in the degenerative disc. Spine (Phila Pa 1976). 2005 Dec 01; 30(23):2683-8. Keshari KR, Lotz JC, Kurhanewicz J, Majumdar S. PMID: 16319755.
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    158. Dependence of mechanical behavior of the murine tail disc on regional material properties: a parametric finite element study. J Biomech Eng. 2005 Dec; 127(7):1158-67. Hsieh AH, Wagner DR, Cheng LY, Lotz JC. PMID: 16502658.
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    159. Disc regeneration: why, when, and how. Neurosurg Clin N Am. 2005 Oct; 16(4):657-63, vii. Lotz JC, Kim AJ. PMID: 16326289.
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    160. The potential role of mesenchymal stem cell therapy for intervertebral disc degeneration: a critical overview. Neurosurg Focus. 2005 Sep 15; 19(3):E4. Acosta FL, Lotz J, Ames CP. PMID: 16190603.
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    161. Basic fibroblast growth factor improves trabecular bone connectivity and bone strength in the lumbar vertebral body of osteopenic rats. Osteoporos Int. 2005 Dec; 16(12):1939-47. Yao W, Hadi T, Jiang Y, Lotz J, Wronski TJ, Lane NE. PMID: 16086094; PMCID: PMC6897353.
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    162. Characterization of intervertebral disc degeneration by high-resolution magic angle spinning (HR-MAS) spectroscopy. Magn Reson Med. 2005 Mar; 53(3):519-27. Keshari KR, Zektzer AS, Swanson MG, Majumdar S, Lotz JC, Kurhanewicz J. PMID: 15723415.
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    163. Effects of controlled dynamic disc distraction on degenerated intervertebral discs: an in vivo study on the rabbit lumbar spine model. Spine (Phila Pa 1976). 2005 Jan 15; 30(2):181-7. Kroeber M, Unglaub F, Guehring T, Guegring T, Nerlich A, Hadi T, Lotz J, Carstens C. PMID: 15644753.
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    164. The effect on anterior column loading due to different vertebral augmentation techniques. Clin Biomech (Bristol, Avon). 2005 Jan; 20(1):25-31. Ananthakrishnan D, Berven S, Deviren V, Cheng K, Lotz JC, Xu Z, Puttlitz CM. PMID: 15567533.
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    165. Carpal tunnel pressure alters median nerve function in a dose-dependent manner: a rabbit model for carpal tunnel syndrome. J Orthop Res. 2005 Jan; 23(1):218-23. Diao E, Shao F, Liebenberg E, Rempel D, Lotz JC. PMID: 15607896.
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    166. Intervertebral disc replacement maintains cervical spine kinetics. Spine (Phila Pa 1976). 2004 Dec 15; 29(24):2809-14. Puttlitz CM, Rousseau MA, Xu Z, Hu S, Tay BK, Lotz JC. PMID: 15599283.
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    167. Introduction: disc degeneration: summary. Spine (Phila Pa 1976). 2004 Dec 01; 29(23):2677-8. An HS, Anderson PA, Haughton VM, Iatridis JC, Kang JD, Lotz JC, Natarajan RN, Oegema TR, Roughley P, Setton LA, Urban JP, Videman T, Andersson GB, Weinstein JN. PMID: 15564916.
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    168. Animal models of intervertebral disc degeneration: lessons learned. Spine (Phila Pa 1976). 2004 Dec 01; 29(23):2742-50. Lotz JC. PMID: 15564923.
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    169. A phase IIA study of the topoisomerase I inhibitor, exatecan mesylate (DX-8951f), administered at two different dose schedules in patients with platinum- and taxane-resistant/refractory ovarian cancer. Gynecol Oncol. 2004 Oct; 95(1):114-9. Clamp A, Adams M, Atkinson R, Boven E, Calvert AH, Cervantes A, Ganesan T, Lotz J, Vasey P, Cheverton P, Jayson GC. PMID: 15385119.
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    170. Biaxial testing of human annulus fibrosus and its implications for a constitutive formulation. Ann Biomed Eng. 2004 Sep; 32(9):1231-42. Bass EC, Ashford FA, Segal MR, Lotz JC. PMID: 15493511.
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    171. Diffraction enhanced imaging of articular cartilage and comparison with micro-computed tomography of the underlying bone structure. Eur Radiol. 2004 Aug; 14(8):1440-8. Majumdar S, Issever AS, Burghardt A, Lotz J, Arfelli F, Rigon L, Heitner G, Menk RH. PMID: 15232709.
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    172. Theoretical model and experimental results for the nonlinear elastic behavior of human annulus fibrosus. J Orthop Res. 2004 Jul; 22(4):901-9. Wagner DR, Lotz JC. PMID: 15183453.
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    173. Ventral approach to the lumbar spine of the Sprague-Dawley rat. Lab Anim (NY). 2004 Jun; 33(6):43-5. Rousseau MA, Bass EC, Lotz JC. PMID: 15179439.
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    174. Biomechanics of cervical laminoplasty: kinetic studies comparing different surgical techniques, temporal effects and the degree of level involvement. Eur Spine J. 2004 May; 13(3):213-21. Puttlitz CM, Deviren V, Smith JA, Kleinstueck FS, Tran QN, Thurlow RW, Eisele P, Lotz JC. PMID: 15007708; PMCID: PMC3468136.
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    175. Intervertebral disc degeneration: the role of the mitochondrial pathway in annulus fibrosus cell apoptosis induced by overload. Am J Pathol. 2004 Mar; 164(3):915-24. Rannou F, Lee TS, Zhou RH, Chin J, Lotz JC, Mayoux-Benhamou MA, Barbet JP, Chevrot A, Shyy JY. PMID: 14982845; PMCID: PMC1613264.
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    176. Biological response of the intervertebral disc to dynamic loading. J Biomech. 2004 Mar; 37(3):329-37. Walsh AJ, Lotz JC. PMID: 14757452.
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    177. Stability analysis of craniovertebral junction fixation techniques. J Bone Joint Surg Am. 2004 Mar; 86(3):561-8. Puttlitz CM, Melcher RP, Kleinstueck FS, Harms J, Bradford DS, Lotz JC. PMID: 14996883.
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    178. Intervertebral disc cell therapy for regeneration: mesenchymal stem cell implantation in rat intervertebral discs. Ann Biomed Eng. 2004 Mar; 32(3):430-4. Crevensten G, Walsh AJ, Ananthakrishnan D, Page P, Wahba GM, Lotz JC, Berven S. PMID: 15095817.
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    179. A three-dimensional MRI analysis of knee kinematics. J Orthop Res. 2004 Mar; 22(2):283-92. Patel VV, Hall K, Ries M, Lotz J, Ozhinsky E, Lindsey C, Lu Y, Majumdar S. PMID: 15013086.
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    180. Heat-induced changes in porcine annulus fibrosus biomechanics. J Biomech. 2004 Feb; 37(2):233-40. Bass EC, Wistrom EV, Diederich CJ, Nau WH, Pellegrino R, Ruberti J, Lotz JC. PMID: 14706326.
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    181. In vivo growth factor treatment of degenerated intervertebral discs. Spine (Phila Pa 1976). 2004 Jan 15; 29(2):156-63. Walsh AJ, Bradford DS, Lotz JC. PMID: 14722406.
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    182. Percutaneous plasma decompression alters cytokine expression in injured porcine intervertebral discs. Spine J. 2004 Jan-Feb; 4(1):88-98. O'Neill CW, Liu JJ, Leibenberg E, Hu SS, Deviren V, Tay BK, Chin CT, Lotz JC. PMID: 14749197.
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    183. Polarization-modulated second harmonic generation imaging: method for quantitative assessment of disorganization in anulus. Conf Proc IEEE Eng Med Biol Soc. 2004; 2004:4982-5. Reiser KM, Rocha-Mendoza I, Wang M, Yankelevich DR, Bratton C, Knoesen A, Lotz JC, Liebenman E. PMID: 17271433.
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    184. Mechanobiology in intervertebral disc degeneration and regeneration. Conf Proc IEEE Eng Med Biol Soc. 2004; 2004:5459. Lotz JC, Staples A, Walsh A, Hsieh AH. PMID: 17271585.
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    185. The compressive creep properties of normal and degenerated murine intervertebral discs. J Orthop Res. 2004 Jan; 22(1):164-9. Palmer EI, Lotz JC. PMID: 14656676.
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    186. Prolonged spinal loading induces matrix metalloproteinase-2 activation in intervertebral discs. Spine (Phila Pa 1976). 2003 Aug 15; 28(16):1781-8. Hsieh AH, Lotz JC. PMID: 12923463.
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    187. Temperature and thermal dose distributions during intradiscal electrothermal therapy in the cadaveric lumbar spine. Spine (Phila Pa 1976). 2003 Aug 01; 28(15):1700-8; discussion 1709. Kleinstueck FS, Diederich CJ, Nau WH, Puttlitz CM, Smith JA, Bradford DS, Lotz JC. PMID: 12897495.
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    188. Dorsal and palmar material properties of the adult human flexor profundus tendon in Zone II. Hand Surg. 2003 Jul; 8(1):53-8. Soejima O, Diao E, Lotz JC, Hariharan JS, Naito M. PMID: 12923935.
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    189. Effect of cementless bowed stem distal surface contour and coronal slot on femoral bone strains and torsional stability. J Arthroplasty. 2003 Jun; 18(4):494-8. Ries MD, Suzuki Y, Renowitzky G, Lotz JC, Barrack RL, Bourne RB, Rorabeck CH. PMID: 12820094.
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    190. Scaphoid kinematic behavior after division of the transverse carpal ligament. J Hand Surg Am. 2003 Mar; 28(2):267-71. Ishiko T, Puttlitz CM, Lotz JC, Diao E. PMID: 12671859.
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    191. Micro-computed tomography evaluation of trabecular bone structure on loaded mice tail vertebrae. Spine (Phila Pa 1976). 2003 Jan 15; 28(2):123-8. Issever AS, Walsh A, Lu Y, Burghardt A, Lotz JC, Majumdar S. PMID: 12544927.
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    192. The effects of synthetic conjugated estrogens, a (cenestin) on trabecular bone structure and strength in the ovariectomized rat model. Osteoporos Int. 2002 Oct; 13(10):816-23. Lane NE, Kumer JL, Majumdar S, Khan M, Lotz J, Stevens RE, Klein R, Phelps KV. PMID: 12378371.
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    193. The internal mechanics of the intervertebral disc under cyclic loading. J Biomech. 2002 Sep; 35(9):1263-71. Riches PE, Dhillon N, Lotz J, Woods AW, McNally DS. PMID: 12163315.
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    194. [Biomechanical properties of bioabsorbable cannulated screws for surgical fixation of dislocated epiphysiolysis capitis femoris]. Orthopade. 2002 Jun; 31(6):563-7. Kröber MW, Rovinsky D, Lotz J, Carstens C, Otsuka NY. PMID: 12149928.
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    195. Impact biomechanics and pelvic deformation during insertion of press-fit acetabular cups. J Arthroplasty. 2002 Apr; 17(3):349-54. Kroeber M, Ries MD, Suzuki Y, Renowitzky G, Ashford F, Lotz J. PMID: 11938513.
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    196. Tenascin-X deficiency mimics Ehlers-Danlos syndrome in mice through alteration of collagen deposition. Nat Genet. 2002 Apr; 30(4):421-5. Mao JR, Taylor G, Dean WB, Wagner DR, Afzal V, Lotz JC, Rubin EM, Bristow J. PMID: 11925569.
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    197. Magnetic resonance imaging measurement of relaxation and water diffusion in the human lumbar intervertebral disc under compression in vitro. Spine (Phila Pa 1976). 2001 Oct 01; 26(19):E437-44. Chiu EJ, Newitt DC, Segal MR, Hu SS, Lotz JC, Majumdar S. PMID: 11698903.
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    198. Postoperative reduction of fibrinolysis as a prognostic factor of fatal outcome. Clin Appl Thromb Hemost. 2001 Oct; 7(4):330-4. Lotz J, Walgenbach S, Peetz D, Dutkowski P, Junginger T, Prellwitz W, Hafner G. PMID: 11697719.
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    199. The effect of static in vivo bending on the murine intervertebral disc. Spine J. 2001 Jul-Aug; 1(4):239-45. Court C, Colliou OK, Chin JR, Liebenberg E, Bradford DS, Lotz JC. PMID: 14588327.
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    200. Effect of frozen storage on the creep behavior of human intervertebral discs. Spine (Phila Pa 1976). 2001 Apr 15; 26(8):883-8. Dhillon N, Bass EC, Lotz JC. PMID: 11317110.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    201. [Effects of early estrogen replacement therapy on bone stability of ovariectomized rats. A biomechanical and radiologic study of the tibial plateau]. Orthopade. 2000 Dec; 29(12):1082-7. Kröber MW, Lane N, Lotz JC, Thomsen M. PMID: 11193261.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    202. Biphasic material properties of lytic bone metastases. Ann Biomed Eng. 2000 Sep; 28(9):1154-8. Whyne CM, Hu SS, Workman KL, Lotz JC. PMID: 11132199.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    203. Intervertebral disc cell death is dependent on the magnitude and duration of spinal loading. Spine (Phila Pa 1976). 2000 Jun 15; 25(12):1477-83. Lotz JC, Chin JR. PMID: 10851095.
      View in: PubMed   Mentions: 90     Fields:    Translation:Animals
    204. Anisotropic shear behavior of the annulus fibrosus: effect of harvest site and tissue prestrain. Med Eng Phys. 2000 Jun; 22(5):349-57. Fujita Y, Wagner DR, Biviji AA, Duncan NA, Lotz JC. PMID: 11121768.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    205. A special theory of biphasic mixtures and experimental results for human annulus fibrosus tested in confined compression. J Biomech Eng. 2000 Apr; 122(2):180-8. Klisch SM, Lotz JC. PMID: 10834159.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    206. Tibial plateau fracture as a measure of early estrogen-dependent bone fragility in rats. J Orthop Res. 2000 Mar; 18(2):326-32. Lotz JC, Kroeber MW, Heilmann M, Pericherla K, Kimmel D, Kinney JH, Lane NE. PMID: 10815836.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    207. Application of a fiber-reinforced continuum theory to multiple deformations of the annulus fibrosus. J Biomech. 1999 Oct; 32(10):1027-36. Klisch SM, Lotz JC. PMID: 10476841.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    208. Inhibition of TGF-beta receptor signaling in osteoblasts leads to decreased bone remodeling and increased trabecular bone mass. Development. 1999 Oct; 126(19):4267-79. Filvaroff E, Erlebacher A, Ye J, Gitelman SE, Lotz J, Heillman M, Derynck R. PMID: 10477295.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    209. Randomized biomechanical study of zone II human flexor tendon repairs. J Hand Surg Am. 1999 Jul; 24(4):871-3. Diao E, Soejima O, Lotz J, Hariharan J. PMID: 10447187.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    210. Comparison of bone-patellar tendon-bone interference screw fixation and hamstring transfemoral screw fixation in anterior cruciate ligament reconstruction. Orthopedics. 1999 Jun; 22(6):587-91. Randall RL, Wolf EM, Heilmann MR, Lotz J. PMID: 10386800.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    211. The biomechanics of prevention and treatment for low back pain: 2nd international workshop. Clin Biomech (Bristol, Avon). 1999 Mar; 14(3):220-3. Lotz JC. PMID: 10651530.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    212. Collagen type I metabolism after bone surgery. Arch Orthop Trauma Surg. 1999; 119(3-4):212-6. Lotz J, Gaertner T, Hahn M, Prellwitz W. PMID: 10392522.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    213. Compression-induced degeneration of the intervertebral disc: an in vivo mouse model and finite-element study. Spine (Phila Pa 1976). 1998 Dec 01; 23(23):2493-506. Lotz JC, Colliou OK, Chin JR, Duncan NA, Liebenberg E. PMID: 9854748.
      View in: PubMed   Mentions: 104     Fields:    Translation:Animals
    214. Use of a collagen-hydroxyapatite matrix in spinal fusion. A rabbit model. Spine (Phila Pa 1976). 1998 Nov 01; 23(21):2276-81. Tay BK, Le AX, Heilman M, Lotz J, Bradford DS. PMID: 9820906.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    215. Hepatocellular hyperplasia, plasmacytoma formation, and extramedullary hematopoiesis in interleukin (IL)-6/soluble IL-6 receptor double-transgenic mice. Am J Pathol. 1998 Aug; 153(2):639-48. Schirmacher P, Peters M, Ciliberto G, Blessing M, Lotz J, Meyer zum Büschenfelde KH, Rose-John S. PMID: 9708822; PMCID: PMC1852966.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    216. [Follow-up of collagen and bone metabolism in patients with cement-free total hip endoprosthesis]. Z Orthop Ihre Grenzgeb. 1998 Jul-Aug; 136(4):304-9. Meurer A, Lotz J, Giesa M, Eckardt A, Prellwitz W, Heine J. PMID: 9795431.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    217. Analytic model to predict the strength of tendon repairs. J Orthop Res. 1998 Jul; 16(4):399-405. Lotz JC, Hariharan JS, Diao E. PMID: 9747779.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    218. Use of ultrasound in spinal arthrodesis. A rabbit model. Spine (Phila Pa 1976). 1998 May 15; 23(10):1142-8. Glazer PA, Heilmann MR, Lotz JC, Bradford DS. PMID: 9615366.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    219. Effect of long-term treatment with GH on bone metabolism, bone mineral density and bone elasticity in GH-deficient adults. Clin Endocrinol (Oxf). 1998 May; 48(5):561-8. Kann P, Piepkorn B, Schehler B, Andreas J, Lotz J, Prellwitz W, Beyer J. PMID: 9666867.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    220. Effect of the pedicle and posterior arch on vertebral body strength predictions in finite element modeling. Spine (Phila Pa 1976). 1998 Apr 15; 23(8):899-907. Whyne CM, Hu SS, Klisch S, Lotz JC. PMID: 9580957.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    221. Frozen storage affects the compressive creep behavior of the porcine intervertebral disc. Spine (Phila Pa 1976). 1997 Dec 15; 22(24):2867-76. Bass EC, Duncan NA, Hariharan JS, Dusick J, Bueff HU, Lotz JC. PMID: 9431622.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    222. Carbonated apatite cement augmentation of pedicle screw fixation in the lumbar spine. Spine (Phila Pa 1976). 1997 Dec 01; 22(23):2716-23. Lotz JC, Hu SS, Chiu DF, Yu M, Colliou O, Poser RD. PMID: 9431604.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    223. Radial tensile properties of the lumbar annulus fibrosus are site and degeneration dependent. J Orthop Res. 1997 Nov; 15(6):814-9. Fujita Y, Duncan NA, Lotz JC. PMID: 9497805.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    224. Partial lacerations of human digital flexor tendons: a biomechanical analysis. J Hand Surg Am. 1997 Nov; 22(6):1011-5. Hariharan JS, Diao E, Soejima O, Lotz JC. PMID: 9471068.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    225. Use of electromagnetic fields in a spinal fusion. A rabbit model. Spine (Phila Pa 1976). 1997 Oct 15; 22(20):2351-6. Glazer PA, Heilmann MR, Lotz JC, Bradford DS. PMID: 9355215.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCTClinical Trials
    226. Biomechanical analysis of multilevel fixation methods in the lumbar spine. Spine (Phila Pa 1976). 1997 Jan 15; 22(2):171-82. Glazer PA, Colliou O, Klisch SM, Bradfore DS, Bueff HU, Lotz JC. PMID: 9122797.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    227. Biomechanical analysis of lumbosacral fixation. Spine (Phila Pa 1976). 1996 May 15; 21(10):1211-22. Glazer PA, Colliou O, Lotz JC, Bradford DS. PMID: 8727196.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    228. Effect of peripheral suture depth on strength of tendon repairs. J Hand Surg Am. 1996 Mar; 21(2):234-9. Diao E, Hariharan JS, Soejima O, Lotz JC. PMID: 8683052.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    229. Magnetic resonance imaging of trabecular bone structure in the distal radius: relationship with X-ray tomographic microscopy and biomechanics. Osteoporos Int. 1996; 6(5):376-85. Majumdar S, Newitt D, Mathur A, Osman D, Gies A, Chiu E, Lotz J, Kinney J, Genant H. PMID: 8931032.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    230. Comparative mechanical analysis of dorsal versus palmar placement of core suture for flexor tendon repairs. J Hand Surg Am. 1995 Sep; 20(5):801-7. Soejima O, Diao E, Lotz JC, Hariharan JS. PMID: 8522748.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    231. Instrumentation of the cervicothoracic junction after destabilization. Spine (Phila Pa 1976). 1995 Aug 15; 20(16):1789-92. Bueff HU, Lotz JC, Colliou OK, Khapchik V, Ashford F, Hu SS, Bozic K, Bradford DS. PMID: 7502135.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    232. Evaluation of an automated chromogenic substrate assay for the rapid determination of hirudin in plasma. Thromb Res. 1995 Jan 15; 77(2):165-73. Hafner G, Fickenscher K, Friesen HJ, Rupprecht HJ, Konheiser U, Ehrenthal W, Lotz J, Prellwitz W. PMID: 7740508.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    233. Stress distributions within the proximal femur during gait and falls: implications for osteoporotic fracture. Osteoporos Int. 1995; 5(4):252-61. Lotz JC, Cheal EJ, Hayes WC. PMID: 7492864.
      View in: PubMed   Mentions: 66     Fields:    Translation:Humans
    234. Gender differences in bone density, skeletal geometry, and fracture biomechanics. Radiology. 1994 Mar; 190(3):636-40. Genant HK, Glüer CC, Lotz JC. PMID: 8115602.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    235. Fracture prediction for the proximal femur using finite element models: Part II--Nonlinear analysis. J Biomech Eng. 1991 Nov; 113(4):361-5. Lotz JC, Cheal EJ, Hayes WC. PMID: 1762431.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    236. Fracture prediction for the proximal femur using finite element models: Part I--Linear analysis. J Biomech Eng. 1991 Nov; 113(4):353-60. Lotz JC, Cheal EJ, Hayes WC. PMID: 1762430.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    237. Mechanical properties of metaphyseal bone in the proximal femur. J Biomech. 1991; 24(5):317-29. Lotz JC, Gerhart TN, Hayes WC. PMID: 2050708.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    238. The use of quantitative computed tomography to estimate risk of fracture of the hip from falls. J Bone Joint Surg Am. 1990 Jun; 72(5):689-700. Lotz JC, Hayes WC. PMID: 2355030.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    239. Biomechanical properties of the proximal femur determined in vitro by single-energy quantitative computed tomography. J Bone Miner Res. 1989 Oct; 4(5):715-22. Esses SI, Lotz JC, Hayes WC. PMID: 2816516.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
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