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    Stephen Hauser, MD

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentNeurology
    Address675 Nelson Rising Lane
    San Francisco CA 94143
    Phone415-476-9211
      Other Positions
      TitleChair, Neurology


       Biography 
       Awards and Honors
      ISNI Conference 2010, Spain2010The Dale McFarlin Memorial Lecture
      President Barak Obama2010Appointed Member, Presidential Commission for the Study of Bioethical Issues
      National Academy of Sciences2009Chair, Committee on Gulf War and Health, Institute of Medicine
      National Multiple Sclerosis Society and the American Academy of Neurology2008John Dystel Prize for Multiple Sclerosis Research
      National Academy of Sciences1991 - 1998Javits Neuroscience Investigator, National Institute of Health

       Overview 
       Overview
      Stephen L. Hauser, M.D. is a graduate of MIT (Phi Beta Kappa) and Harvard Medical School (Magna Cum Laude). He trained in internal medicine at the New York Hospital-Cornell Medical Center, in neurology at the Massachusetts General Hospital (MGH), and in immunology at Harvard Medical School and the Institute Pasteur in Paris, France, and was a faculty member at Harvard Medical School before moving to UCSF in 1992. A neuroimmunologist, Dr. Hauser's research has advanced our understanding of the genetic basis, immune mechanisms, and treatment of multiple sclerosis. Dr. Hauser is a fellow of the American Academy of Arts and Sciences and the American Academy of Physicians, a member of the Institute of Medicine of the National Academy of Sciences (previous Chair of Section 7 and current Chair of the Committee on Gulf War and Health Outcomes), an editor of the textbook Harrison's Principles of Internal Medicine, and editor-in-chief of Annals of Neurology. He has served as President of the American Neurological Association and President of the Medical Staff at UCSF. He also serves on several scientific advisory boards for nonprofit organizations. Dr. Hauser has received numerous awards and honors for his work, including the Jacob Javits Neuroscience Investigator Award and the 2008 John Dystel Prize for Multiple Sclerosis Research.

      In April, 2010 Dr. Hauser was appointed by President Obama to the Presidential Commission for the Study of Bioethical Issues charged with advising the President on issues that may emerge from advances in biomedicine and related areas of science and technology.


       ORNG Applications 
       Websites
       In The News
       Awarded Grants
       Global Health
       More Info

       Bibliographic 
       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Palanichamy A, Apeltsin L, Kuo TC, Sirota M, Wang S, Pitts SJ, Sundar PD, Telman D, Zhao LZ, Derstine M, Abounasr A, Hauser SL, von Büdingen HC. Immunoglobulin class-switched B cells form an active immune axis between CNS and periphery in multiple sclerosis. Sci Transl Med. 2014 Aug 6; 6(248):248ra106.
        View in: PubMed
      2. Azevedo CJ, Kornak J, Chu P, Sampat M, Okuda DT, Cree BA, Nelson SJ, Hauser SL, Pelletier D. In vivo evidence of glutamate toxicity in multiple sclerosis. Ann Neurol. 2014 Aug; 76(2):269-78.
        View in: PubMed
      3. Azevedo CJ, Kornak J, Chu P, Sampat M, Okuda DT, Cree BA, Nelson SJ, Hauser SL, Pelletier D. In vivo evidence of glutamate toxicity in multiple sclerosis. Ann Neurol. 2014 Aug; 76(2):269-78.
        View in: PubMed
      4. Mei F, Fancy SP, Shen YA, Niu J, Zhao C, Presley B, Miao E, Lee S, Mayoral SR, Redmond SA, Etxeberria A, Xiao L, Franklin RJ, Green A, Hauser SL, Chan JR. Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis. Nat Med. 2014 Jul 6.
        View in: PubMed
      5. Gourraud PA, Khankhanian P, Cereb N, Yang SY, Feolo M, Maiers M, D Rioux J, Hauser S, Oksenberg J. HLA Diversity in the 1000 Genomes Dataset. PLoS One. 2014; 9(7):e97282.
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      6. Llufriu S, Kornak J, Ratiney H, Oh J, Brenneman D, Cree BA, Sampat M, Hauser SL, Nelson SJ, Pelletier D. Magnetic resonance spectroscopy markers of disease progression in multiple sclerosis. JAMA Neurol. 2014 Jul 1; 71(7):840-7.
        View in: PubMed
      7. Palanichamy A, Jahn S, Nickles D, Derstine M, Abounasr A, Hauser SL, Baranzini SE, Leppert D, von Büdingen HC. Rituximab Efficiently Depletes Increased CD20-Expressing T Cells in Multiple Sclerosis Patients. J Immunol. 2014 Jul 15; 193(2):580-6.
        View in: PubMed
      8. Hauser SL. What ethics integration looks like in neuroscience research. Ann Neurol. 2014 May; 75(5):623-4.
        View in: PubMed
      9. Morris DL, Fernando MM, Taylor KE, Chung SA, Nititham J, Alarcón-Riquelme ME, Barcellos LF, Behrens TW, Cotsapas C, Gaffney PM, Graham RR, Pons-Estel BA, Gregersen PK, Harley JB, Hauser SL, Hom G, Langefeld CD, Noble JA, Rioux JD, Seldin MF. MHC associations with clinical and autoantibody manifestations in European SLE. Genes Immun. 2014 Apr; 15(4):210-7.
        View in: PubMed
      10. Bankoti J, Apeltsin L, Hauser SL, Allen S, Albertolle ME, Witkowska HE, von Büdingen HC. In multiple sclerosis, oligoclonal bands connect to peripheral B-cell responses. Ann Neurol. 2014 Feb; 75(2):266-76.
        View in: PubMed
      11. Hauser SL, Johnston SC, Ferriero DM, Josephson SA, Lowenstein DH, Messing RO, Oksenberg JR. Quo vadis? - peering into the future. Ann Neurol. 2013 Dec; 74(6):A5-7.
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      12. Johnston SC, Ferriero DM, Josephson SA, Lowenstein DH, Messing RO, Oksenberg J, Stewart A, Hauser SL. Have the Annals editors added value? Ann Neurol. 2013 Nov; 74(5):A7-9.
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      13. Harbo HF, Isobe N, Berg-Hansen P, Bos SD, Caillier SJ, Gustavsen MW, Mero IL, Celius EG, Hauser SL, Oksenberg JR, Gourraud PA. Oligoclonal bands and age at onset correlate with genetic risk score in multiple sclerosis. Mult Scler. 2014 May; 20(6):660-8.
        View in: PubMed
      14. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet. 2013 Nov; 45(11):1353-60.
        View in: PubMed
      15. Hauser SL, Chan JR, Oksenberg JR. Multiple sclerosis: Prospects and promise. Ann Neurol. 2013 Sep; 74(3):317-27.
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      16. Brown RH, Hauser SL. Introduction to a special edition of Annals: Therapeutic prospects. Ann Neurol. 2013 Sep; 74(3):A15.
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      17. Josephson SA, Johnston SC, Hauser SL. Blockbusters for cheap? The difficulties surrounding generic biologics. Ann Neurol. 2013 Sep; 74(3):A7-8.
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      18. Isobe N, Damotte V, Lo Re V, Ban M, Pappas D, Guillot-Noel L, Rebeix I, Compston A, Mack T, Cozen W, Fontaine B, Hauser SL, Oksenberg JR, Sawcer S, Gourraud PA. Genetic burden in multiple sclerosis families. Genes Immun. 2013 Oct; 14(7):434-40.
        View in: PubMed
      19. Hauser SL, Johnston SC. Neurology: Violence at home. Ann Neurol. 2013 Aug; 74(2):A5-6.
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      20. Hauser SL, Johnston SC. Living in the time of sequestration. Ann Neurol. 2013 Jul; 74(1):A5-6.
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      21. Schulze-Topphoff U, Casazza S, Varrin-Doyer M, Michel K, Sobel RA, Hauser SL, Oksenberg JR, Zamvil SS, Baranzini SE. Tob1 plays a critical role in the activation of encephalitogenic T cells in CNS autoimmunity. J Exp Med. 2013 Jul 1; 210(7):1301-9.
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      22. Isobe N, Gourraud PA, Harbo HF, Caillier SJ, Santaniello A, Khankhanian P, Maiers M, Spellman S, Cereb N, Yang S, Pando MJ, Piccio L, Cross AH, De Jager PL, Cree BA, Hauser SL, Oksenberg JR. Genetic risk variants in African Americans with multiple sclerosis. Neurology. 2013 Jul 16; 81(3):219-27.
        View in: PubMed
      23. Nickles D, Chen HP, Li MM, Khankhanian P, Madireddy L, Caillier SJ, Santaniello A, Cree BA, Pelletier D, Hauser SL, Oksenberg JR, Baranzini SE. Blood RNA profiling in a large cohort of multiple sclerosis patients and healthy controls. Hum Mol Genet. 2013 Oct 15; 22(20):4194-205.
        View in: PubMed
      24. Johnston SC, Hauser SL. The dangers of clinical conviction: an "M&M" of endovascular therapies for stroke. Ann Neurol. 2013 Jun; 73(6):A5-6.
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      25. Josephson SA, Johnston SC, Hauser SL. The neurologic revolving door: time to pay attention to readmissions. Ann Neurol. 2013 May; 73(5):A5-6.
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      26. Hauser SL, Johnston SC. Big neuroscience. Ann Neurol. 2013 Apr; 73(4):A5-6.
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      27. Hauser SL, Josephson SA, Johnston SC. Multiple sclerosis: monotherapy rules. Ann Neurol. 2013 Mar; 73(3):A5-6.
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      28. Ban M, Caillier S, Mero IL, Myhr KM, Celius EG, Aarseth J, Torkildsen Ø, Harbo HF, Oksenberg J, Hauser SL, Sawcer S, Compston A. No evidence of association between mutant alleles of the CYP27B1 gene and multiple sclerosis. Ann Neurol. 2013 Mar; 73(3):430-2.
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      29. Gourraud PA, Sdika M, Khankhanian P, Henry RG, Beheshtian A, Matthews PM, Hauser SL, Oksenberg JR, Pelletier D, Baranzini SE. A genome-wide association study of brain lesion distribution in multiple sclerosis. Brain. 2013 Apr; 136(Pt 4):1012-24.
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      30. Johnston SC, Josephson SA, Hauser SL. Are relative value units hurting healthcare? Ann Neurol. 2013 Feb; 73(2):A5-6.
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      31. Hauser SL. Reply to Dr Sethi. Ann Neurol. 2013 Jan; 73(1):147.
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      32. Hauser SL, Johnston SC. DSM-V: psychodrama on the public stage. Ann Neurol. 2013 Jan; 73(1):A5-6.
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      33. McElroy JP, Krupp LB, Johnson BA, McCauley JL, Qi Z, Caillier SJ, Gourraud PA, Yu J, Nathanson L, Belman AL, Hauser SL, Waubant E, Hedges DJ, Oksenberg JR. Copy number variation in pediatric multiple sclerosis. Mult Scler. 2013 Jul; 19(8):1014-21.
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      34. Josephson SA, Johnston SC, Hauser SL. Electronic medical records and the academic neurologist: when carrots turn into sticks. Ann Neurol. 2012 Dec; 72(6):A5-6.
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      35. von Büdingen HC, Kuo TC, Sirota M, van Belle CJ, Apeltsin L, Glanville J, Cree BA, Gourraud PA, Schwartzburg A, Huerta G, Telman D, Sundar PD, Casey T, Cox DR, Hauser SL. B cell exchange across the blood-brain barrier in multiple sclerosis. J Clin Invest. 2012 Dec 3; 122(12):4533-43.
        View in: PubMed
      36. Hauser SL, Josephson SA, Johnston SC. Deciphering the signature injury. Ann Neurol. 2012 Nov; 72(5):A5-6.
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      37. Morris DL, Taylor KE, Fernando MM, Nititham J, Alarcón-Riquelme ME, Barcellos LF, Behrens TW, Cotsapas C, Gaffney PM, Graham RR, Pons-Estel BA, Gregersen PK, Harley JB, Hauser SL, Hom G. Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans. Am J Hum Genet. 2012 Nov 2; 91(5):778-93.
        View in: PubMed
      38. Johnston SC, Hauser SL. Healthcare costs: Eden's apple? Ann Neurol. 2012 Oct; 72(4):A4-5.
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      39. Nickles D, Madireddy L, Yang S, Khankhanian P, Lincoln S, Hauser SL, Oksenberg JR, Baranzini SE. In depth comparison of an individual's DNA and its lymphoblastoid cell line using whole genome sequencing. BMC Genomics. 2012; 13:477.
        View in: PubMed
      40. Hauser SL. Beaten into action: a perspective on blood sports. Ann Neurol. 2012 Sep; 72(3):A4-5.
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      41. Hauser SL. Note to aspiring clinician scientists: skies are clearing. Ann Neurol. 2012 Aug; 72(2):A5-6.
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      42. Mowry EM, Waubant E, McCulloch CE, Okuda DT, Evangelista AA, Lincoln RR, Gourraud PA, Brenneman D, Owen MC, Qualley P, Bucci M, Hauser SL, Pelletier D. Vitamin D status predicts new brain magnetic resonance imaging activity in multiple sclerosis. Ann Neurol. 2012 Aug; 72(2):234-40.
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      43. Gourraud PA, Harbo HF, Hauser SL, Baranzini SE. The genetics of multiple sclerosis: an up-to-date review. Immunol Rev. 2012 Jul; 248(1):87-103.
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      44. Hauser SL, Josephson SA, Johnston SC. Florbetapir: knowing one's future. Ann Neurol. 2012 Jun; 71(6):A6.
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      45. Hauser SL, Johnston SC. Multiple sclerosis drugs: sticker shock. Ann Neurol. 2012 May; 71(5):A5-6.
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      46. Hedges DJ, Hamilton-Nelson KL, Sacharow SJ, Nations L, Beecham GW, Kozhekbaeva ZM, Butler BL, Cukier HN, Whitehead PL, Ma D, Jaworski JM, Nathanson L, Lee JM, Hauser SL, Oksenberg JR, Cuccaro ML, Haines JL, Gilbert JR, Pericak-Vance MA. Evidence of novel fine-scale structural variation at autism spectrum disorder candidate loci. Mol Autism. 2012; 3:2.
        View in: PubMed
      47. Johnston SC, Hauser SL. The neurological exam: striking a nerve. Ann Neurol. 2012 Mar; 71(3):A5.
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      48. Johnston SC, Hauser SL. Modern care for neurological problems must address waste. Ann Neurol. 2012 Feb; 71(2):A5-6.
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      49. Villoslada P, Cuneo A, Gelfand J, Hauser SL, Green A. Color vision is strongly associated with retinal thinning in multiple sclerosis. Mult Scler. 2012 Jul; 18(7):991-9.
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      50. Stewart AF, Ferriero DM, Josephson SA, Lowenstein DH, Messing RO, Oksenberg JR, Johnston SC, Hauser SL. Fighting decision fatigue. Ann Neurol. 2012 Jan; 71(1):A5-A15.
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      51. Patsopoulos NA. Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol. 2011 Dec; 70(6):897-912.
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      52. Oksenberg JR, Hauser SL. Decoding multiple sclerosis. Ann Neurol. 2011 Dec; 70(6):A5-7.
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      53. Glanville J, Kuo TC, von Büdingen HC, Guey L, Berka J, Sundar PD, Huerta G, Mehta GR, Oksenberg JR, Hauser SL, Cox DR, Rajpal A, Pons J. Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation. Proc Natl Acad Sci U S A. 2011 Dec 13; 108(50):20066-71.
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      54. Hauser SL, Johnston SC. Benefits of medical research: Hollywood weighs in. Ann Neurol. 2011 Nov; 70(5):A5-6.
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      55. Kappos L, Li D, Calabresi PA, O'Connor P, Bar-Or A, Barkhof F, Yin M, Leppert D, Glanzman R, Tinbergen J, Hauser SL. Ocrelizumab in relapsing-remitting multiple sclerosis: a phase 2, randomised, placebo-controlled, multicentre trial. Lancet. 2011 Nov 19; 378(9805):1779-87.
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      56. Hauser SL, Johnston SC. Global clinical trials: challenges ahead. Ann Neurol. 2011 Oct; 70(4):A8-9.
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      57. Curran WJ, Paulus R, Langer CJ, Komaki R, Lee JS, Hauser S, Movsas B, Wasserman T, Rosenthal SA, Gore E, Machtay M, Sause W, Cox JD. Sequential vs. concurrent chemoradiation for stage III non-small cell lung cancer: randomized phase III trial RTOG 9410. J Natl Cancer Inst. 2011 Oct 5; 103(19):1452-60.
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      58. Hauser SL, Johnston SC. Waking up to narcolepsy. Ann Neurol. 2011 Sep; 70(3):A5-6.
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      59. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature. 2011 Aug 11; 476(7359):214-9.
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      60. Johnston SC, Hauser SL. The beautiful and ethereal neurological exam: an appeal for research. Ann Neurol. 2011 Aug; 70(2):A9-A10.
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      61. Kappos L, Bates D, Edan G, Eraksoy M, Garcia-Merino A, Grigoriadis N, Hartung HP, Havrdová E, Hillert J, Hohlfeld R, Kremenchutzky M, Lyon-Caen O, Miller A, Pozzilli C, Ravnborg M, Saida T, Sindic C, Vass K, Clifford DB, Hauser S, Major EO, O'Connor PW, Weiner HL, Clanet M, Gold R, Hirsch HH, Radü EW, Sørensen PS, King J. Natalizumab treatment for multiple sclerosis: updated recommendations for patient selection and monitoring. Lancet Neurol. 2011 Aug; 10(8):745-58.
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      62. McElroy JP, Isobe N, Gourraud PA, Caillier SJ, Matsushita T, Kohriyama T, Miyamoto K, Nakatsuji Y, Miki T, Hauser SL, Oksenberg JR, Kira J. SNP-based analysis of the HLA locus in Japanese multiple sclerosis patients. Genes Immun. 2011 Oct; 12(7):523-30.
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      63. Zuvich RL, Bush WS, McCauley JL, Beecham AH, De Jager PL. Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA-CLEC16A-SOCS1 gene complex. Hum Mol Genet. 2011 Sep 1; 20(17):3517-24.
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      64. Gelfand JM, Cree BA, McElroy J, Oksenberg J, Green R, Mowry EM, Miller JW, Hauser SL, Green AJ. Vitamin D in African Americans with multiple sclerosis. Neurology. 2011 May 24; 76(21):1824-30.
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      65. Roosendaal SD, Bendfeldt K, Vrenken H, Polman CH, Borgwardt S, Radue EW, Kappos L, Pelletier D, Hauser SL, Matthews PM, Barkhof F, Geurts JJ. Grey matter volume in a large cohort of MS patients: relation to MRI parameters and disability. Mult Scler. 2011 Sep; 17(9):1098-106.
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      66. Johnston SC, Hauser SL. The NIH shuffle, NCATS, and neurology. Ann Neurol. 2011 May; 69(5):A9-10.
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      67. Hauser SL, Johnston SC. Extraordinary claims require extraordinary evidence. Ann Neurol. 2011 Apr; 69(4):A9-A10.
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      68. Johnston SC, Hauser SL, Desmond-Hellmann S. Enhancing ties between academia and industry to improve health. Nat Med. 2011 Apr; 17(4):434-6.
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      69. Hauser SL, Johnston SC. Scientific literacy and the media. Ann Neurol. 2011 Mar; 69(3):A9-10.
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      70. Bush WS, McCauley JL, DeJager PL, Dudek SM, Hafler DA, Gibson RA, Matthews PM, Kappos L, Naegelin Y, Polman CH, Hauser SL, Oksenberg J, Haines JL, Ritchie MD. A knowledge-driven interaction analysis reveals potential neurodegenerative mechanism of multiple sclerosis susceptibility. Genes Immun. 2011 Jul; 12(5):335-40.
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      71. Wang JH, Pappas D, De Jager PL, Pelletier D, de Bakker PI, Kappos L, Polman CH. Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data. Genome Med. 2011; 3(1):3.
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      72. Gourraud PA, McElroy JP, Caillier SJ, Johnson BA, Santaniello A, Hauser SL, Oksenberg JR. Aggregation of multiple sclerosis genetic risk variants in multiple and single case families. Ann Neurol. 2011 Jan; 69(1):65-74.
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      73. Josephson SA, Hauser SL. Neurologic education 2011: new challenges and opportunities. Ann Neurol. 2010 Dec; 68(6):A9-10.
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      74. Khankhanian P, Gourraud PA, Caillier SJ, Santaniello A, Hauser SL, Baranzini SE, Oksenberg JR. Genetic variation in the odorant receptors family 13 and the mhc loci influence mate selection in a multiple sclerosis dataset. BMC Genomics. 2010; 11:626.
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      75. Josephson SA, Hauser SL, Johnston SC. Malignant middle cerebral artery stroke: Where ischemia meets the scalpel. Ann Neurol. 2010 Oct; 68(4):A6-8.
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      76. Hauser SL, Johnston SC. Fred Plum (1924-2010) and the founding of the Annals of Neurology. Ann Neurol. 2010 Sep; 68(3):A5-7.
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      77. Baranzini SE, Srinivasan R, Khankhanian P, Okuda DT, Nelson SJ, Matthews PM, Hauser SL, Oksenberg JR, Pelletier D. Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis. Brain. 2010 Sep; 133(9):2603-11.
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      78. Briggs FB, Bartlett SE, Goldstein BA, Wang J, McCauley JL, Zuvich RL, De Jager PL, Rioux JD, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Oksenberg JR, Sawcer SJ, Pericak-Vance MA, Haines JL. Evidence for CRHR1 in multiple sclerosis using supervised machine learning and meta-analysis in 12,566 individuals. Hum Mol Genet. 2010 Nov 1; 19(21):4286-95.
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      79. Johnston SC, Hauser SL. The challenge of publishing newsworthy epidemiology. Ann Neurol. 2010 Aug; 68(2):A8-10.
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      80. Hauser SL, Johnston SC. 4-aminopyridine: new life for an old drug. Ann Neurol. 2010 Jul; 68(1):A8-9.
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      81. Cree BA, Rioux JD, McCauley JL, Gourraud PA, Goyette P, McElroy J, De Jager P, Santaniello A, Vyse TJ, Gregersen PK, Mirel D, Hafler DA, Haines JL, Pericak-Vance MA, Compston A, Sawcer SJ, Oksenberg JR, Hauser SL. A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01. PLoS One. 2010; 5(6):e11296.
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      82. Ban M, McCauley JL, Zuvich R, Baker A, Bergamaschi L, Cox M, Kemppinen A, D'Alfonso S, Guerini FR, Lechner-Scott J, Dudbridge F, Wason J, Robertson NP, De Jager PL, Hafler DA, Barcellos LF, Ivinson AJ, Sexton D, Oksenberg JR, Hauser SL, Pericak-Vance MA, Haines J, Compston A, Sawcer S. A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis. Genes Immun. 2010 Dec; 11(8):660-4.
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      83. Briggs FB, Goldstein BA, McCauley JL, Zuvich RL, De Jager PL, Rioux JD, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Oksenberg JR, Sawcer SJ, Pericak-Vance MA, Haines JL, Barcellos LF. Variation within DNA repair pathway genes and risk of multiple sclerosis. Am J Epidemiol. 2010 Jul 15; 172(2):217-24.
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      84. Lack of support for association between the KIF1B rs10492972[C] variant and multiple sclerosis. Nat Genet. 2010 Jun; 42(6):469-70; author reply 470-1.
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      85. Oksenberg JR, Hauser SL. Mapping the human genome with newfound precision. Ann Neurol. 2010 Jun; 67(6):A8-A10.
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      86. McElroy JP, Cree BA, Caillier SJ, Gregersen PK, Herbert J, Khan OA, Freudenberg J, Lee A, Bridges SL, Hauser SL, Oksenberg JR, Gourraud PA. Refining the association of MHC with multiple sclerosis in African Americans. Hum Mol Genet. 2010 Aug 1; 19(15):3080-8.
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      87. Ferriero DM, Hauser SL. Supply does not satisfy demand in child neurology. Ann Neurol. 2010 May; 67(5):A5-6.
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      88. Baranzini SE, Mudge J, van Velkinburgh JC, Khankhanian P, Khrebtukova I, Miller NA, Zhang L, Farmer AD, Bell CJ, Kim RW, May GD, Woodward JE, Caillier SJ, McElroy JP, Gomez R, Pando MJ, Clendenen LE, Ganusova EE, Schilkey FD, Ramaraj T, Khan OA, Huntley JJ, Luo S, Kwok PY, Wu TD, Schroth GP, Oksenberg JR, Hauser SL, Kingsmore SF. Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis. Nature. 2010 Apr 29; 464(7293):1351-6.
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      89. Green AJ, McQuaid S, Hauser SL, Allen IV, Lyness R. Ocular pathology in multiple sclerosis: retinal atrophy and inflammation irrespective of disease duration. Brain. 2010 Jun; 133(Pt 6):1591-601.
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      90. Hauser SL, Johnston SC, Stewart AF. Neuroreconciliation and the health care debate. Ann Neurol. 2010 Apr; 67(4):A5-8.
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      91. Bar-Or A, Fawaz L, Fan B, Darlington PJ, Rieger A, Ghorayeb C, Calabresi PA, Waubant E, Hauser SL, Zhang J, Smith CH. Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS? Ann Neurol. 2010 Apr; 67(4):452-61.
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      92. Bronson PG, Caillier S, Ramsay PP, McCauley JL, Zuvich RL, De Jager PL, Rioux JD, Ivinson AJ, Compston A, Hafler DA, Sawcer SJ, Pericak-Vance MA, Haines JL. CIITA variation in the presence of HLA-DRB1*1501 increases risk for multiple sclerosis. Hum Mol Genet. 2010 Jun 1; 19(11):2331-40.
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      93. Jakkula E, Leppä V, Sulonen AM, Varilo T, Kallio S, Kemppinen A, Purcell S, Koivisto K, Tienari P, Sumelahti ML, Elovaara I, Pirttilä T, Reunanen M, Aromaa A, Oturai AB, Søndergaard HB, Harbo HF, Mero IL, Gabriel SB, Mirel DB, Hauser SL, Kappos L, Polman C, De Jager PL, Hafler DA, Daly MJ, Palotie A, Saarela J, Peltonen L. Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene. Am J Hum Genet. 2010 Feb 12; 86(2):285-91.
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      94. Hauser SL, Lowenstein DH, Johnston SC. Getting youth in the game: can we accelerate training for clinician-scientists? Ann Neurol. 2010 Feb; 67(2):A5-6.
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      95. Zuvich RL, McCauley JL, Oksenberg JR, Sawcer SJ, De Jager PL. Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility. Hum Genet. 2010 Mar; 127(5):525-35.
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      96. Hauser SL, Johnston SC, Ferriero DM, Lowenstein DH, Josephson SA, Messing RO, Oksenberg JR, Stewart AF. Status report: the Annals in 2010. Ann Neurol. 2010 Jan; 67(1):A5-12.
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      97. Bryc K, Auton A, Nelson MR, Oksenberg JR, Hauser SL, Williams S, Froment A, Bodo JM, Wambebe C, Tishkoff SA, Bustamante CD. Genome-wide patterns of population structure and admixture in West Africans and African Americans. Proc Natl Acad Sci U S A. 2010 Jan 12; 107(2):786-91.
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      98. Hauser SL, Johnston SC. Research trainees in the clinical neurosciences: still a shallow pool. Ann Neurol. 2009 Dec; 66(6):A4-5.
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      99. Johnston SC, Hauser SL. IOM task impossible: set the agenda for neurological comparative effectiveness research. Ann Neurol. 2009 Nov; 66(5):A4-6.
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      100. Johnson BA, Wang J, Taylor EM, Caillier SJ, Herbert J, Khan OA, Cross AH, De Jager PL, Gourraud PA, Cree BC, Hauser SL, Oksenberg JR. Multiple sclerosis susceptibility alleles in African Americans. Genes Immun. 2010 Jun; 11(4):343-50.
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      101. Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases. Proc Natl Acad Sci U S A. 2009 Nov 3; 106(44):18680-5.
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      102. Hawker K, O'Connor P, Freedman MS, Calabresi PA, Antel J, Simon J, Hauser S, Waubant E, Vollmer T, Panitch H, Zhang J, Chin P, Smith CH. Rituximab in patients with primary progressive multiple sclerosis: results of a randomized double-blind placebo-controlled multicenter trial. Ann Neurol. 2009 Oct; 66(4):460-71.
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      103. Hauser SL, Johnston SC. Balancing risk and reward: the question of natalizumab. Ann Neurol. 2009 Sep; 66(3):A7-8.
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      104. Johnston SC, Hauser SL. Disparities in care: guilty until proven innocent. Ann Neurol. 2009 Aug; 66(2):A7-8.
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      105. McCauley JL, Zuvich RL, Bradford Y, Kenealy SJ, Schnetz-Boutaud N, Gregory SG, Hauser SL, Oksenberg JR, Mortlock DP, Pericak-Vance MA, Haines JL. Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis. Genes Immun. 2009 Oct; 10(7):624-30.
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      106. Hauser SL, Johnston SC. Journeys in complex genetics: music and mental illness. Ann Neurol. 2009 Jul; 66(1):A7-9.
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      107. De Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, Aggarwal NT, Piccio L, Raychaudhuri S, Tran D, Aubin C, Briskin R, Romano S. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet. 2009 Jul; 41(7):776-82.
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      108. Johnston SC, Hauser SL. Crowdsourcing scientific innovation. Ann Neurol. 2009 Jun; 65(6):A7-8.
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      109. Mowry EM, Beheshtian A, Waubant E, Goodin DS, Cree BA, Qualley P, Lincoln R, George MF, Gomez R, Hauser SL, Okuda DT, Pelletier D. Quality of life in multiple sclerosis is associated with lesion burden and brain volume measures. Neurology. 2009 May 19; 72(20):1760-5.
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      110. Hauser SL, Stewart AF, Johnston SC. Message from the editor: on humility. Ann Neurol. 2009 May; 65(5):A7-8.
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      111. Johnston SC, Hauser SL. Economic over-stimulation? Ann Neurol. 2009 Apr; 65(4):A7-8.
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      112. Ban M, Goris A, Lorentzen AR, Baker A, Mihalova T, Ingram G, Booth DR, Heard RN, Stewart GJ, Bogaert E, Dubois B, Harbo HF, Celius EG, Spurkland A, Strange R, Hawkins C, Robertson NP, Dudbridge F, Wason J, De Jager PL, Hafler D, Rioux JD, Ivinson AJ, McCauley JL, Pericak-Vance M, Oksenberg JR, Hauser SL, Sexton D, Haines J, Sawcer S. Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor. Eur J Hum Genet. 2009 Oct; 17(10):1309-13.
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      113. Baranzini SE, Galwey NW, Wang J, Khankhanian P, Lindberg R, Pelletier D, Wu W, Uitdehaag BM, Kappos L. Pathway and network-based analysis of genome-wide association studies in multiple sclerosis. Hum Mol Genet. 2009 Jun 1; 18(11):2078-90.
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      114. Hauser SL, Johnston SC. Personalized genetic scans: with gifts like these... Ann Neurol. 2009 Mar; 65(3):A7-9.
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      115. De Jager PL, Baecher-Allan C, Maier LM, Arthur AT, Ottoboni L, Barcellos L, McCauley JL, Sawcer S, Goris A, Saarela J, Yelensky R, Price A, Leppa V, Patterson N, de Bakker PI, Tran D, Aubin C, Pobywajlo S, Rossin E, Hu X, Ashley CW, Choy E, Rioux JD, Pericak-Vance MA, Ivinson A, Booth DR, Stewart GJ, Palotie A, Peltonen L, Dubois B, Haines JL, Weiner HL, Compston A, Hauser SL, Daly MJ, Reich D, Oksenberg JR, Hafler DA. The role of the CD58 locus in multiple sclerosis. Proc Natl Acad Sci U S A. 2009 Mar 31; 106(13):5264-9.
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      116. Johnston SC, Hauser SL. Comparative effectiveness research in the neurosciences. Ann Neurol. 2009 Feb; 65(2):A6-8.
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      117. Cree BA, Reich DE, Khan O, De Jager PL, Nakashima I, Takahashi T, Bar-Or A, Tong C, Hauser SL, Oksenberg JR. Modification of Multiple Sclerosis Phenotypes by African Ancestry at HLA. Arch Neurol. 2009 Feb; 66(2):226-33.
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      118. Maier LM, Lowe CE, Cooper J, Downes K, Anderson DE, Severson C, Clark PM, Healy B, Walker N, Aubin C, Oksenberg JR, Hauser SL, Compston A, Sawcer S. IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production. PLoS Genet. 2009 Jan; 5(1):e1000322.
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      119. Okuda DT, Mowry EM, Beheshtian A, Waubant E, Baranzini SE, Goodin DS, Hauser SL, Pelletier D. Incidental MRI anomalies suggestive of multiple sclerosis: the radiologically isolated syndrome. Neurology. 2009 Mar 3; 72(9):800-5.
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      120. Hauser SL, Johnston SC. Translational research for a new administration: what sort of change to believe in? Ann Neurol. 2008 Dec; 64(6):A5-6.
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      121. Okuda DT, Srinivasan R, Oksenberg JR, Goodin DS, Baranzini SE, Beheshtian A, Waubant E, Zamvil SS, Leppert D, Qualley P, Lincoln R, Gomez R, Caillier S, George M, Wang J, Nelson SJ, Cree BA, Hauser SL, Pelletier D. Genotype-Phenotype correlations in multiple sclerosis: HLA genes influence disease severity inferred by 1HMR spectroscopy and MRI measures. Brain. 2009 Jan; 132(Pt 1):250-9.
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      122. Baranzini SE, Wang J, Gibson RA, Galwey N, Naegelin Y, Barkhof F, Radue EW, Lindberg RL, Uitdehaag BM, Johnson MR, Angelakopoulou A, Hall L, Richardson JC, Prinjha RK, Gass A, Geurts JJ, Kragt J, Sombekke M, Vrenken H, Qualley P, Lincoln RR, Gomez R, Caillier SJ, George MF, Mousavi H, Guerrero R, Okuda DT, Cree BA, Green AJ, Waubant E, Goodin DS, Pelletier D, Matthews PM, Hauser SL, Kappos L, Polman CH, Oksenberg JR. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Hum Mol Genet. 2009 Feb 15; 18(4):767-78.
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      123. Johnston SC, Hauser SL. Peer review at National Institutes of Health: small steps forward. Ann Neurol. 2008 Nov; 64(5):A15-7.
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      124. Hauser SL. Multiple lessons for multiple sclerosis. N Engl J Med. 2008 Oct 23; 359(17):1838-41.
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      125. Caillier SJ, Briggs F, Cree BA, Baranzini SE, Fernandez-Viña M, Ramsay PP, Khan O, Royal W, Hauser SL, Barcellos LF, Oksenberg JR. Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis. J Immunol. 2008 Oct 15; 181(8):5473-80.
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      126. Hauser SL, Johnston SC. Scripts for science: a new wrinkle on academic ties with industry. Ann Neurol. 2008 Oct; 64(4):A13-5.
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      127. Johnston SC, Hauser SL. Investigator balkanization. Ann Neurol. 2008 Sep; 64(3):A11-2.
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      128. Nelson MR, Bryc K, King KS, Indap A, Boyko AR, Novembre J, Briley LP, Maruyama Y, Waterworth DM, Waeber G, Vollenweider P, Oksenberg JR, Hauser SL, Stirnadel HA, Kooner JS, Chambers JC, Jones B, Mooser V, Bustamante CD, Roses AD, Burns DK, Ehm MG, Lai EH. The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research. Am J Hum Genet. 2008 Sep; 83(3):347-58.
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      129. Corvol JC, Pelletier D, Henry RG, Caillier SJ, Wang J, Pappas D, Casazza S, Okuda DT, Hauser SL, Oksenberg JR, Baranzini SE. Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after the initial neurological event. Proc Natl Acad Sci U S A. 2008 Aug 19; 105(33):11839-44.
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      130. Hauser SL, Johnston SC. An election season prescription for healthcare. Ann Neurol. 2008 Aug; 64(2):A8-9.
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      131. Johnston SC, Hauser SL. Neurological disease on the global agenda. Ann Neurol. 2008 Jul; 64(1):A11-2.
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      132. Barcellos LF, Ramsay PP, Caillier SJ, Sawcer S, Haines J, Schmidt S, Pericak-Vance M, Compston DA, Gabatto P, Hauser SL, Oksenberg JR. Genetic variation in nitric oxide synthase 2A (NOS2A) and risk for multiple sclerosis. Genes Immun. 2008 Sep; 9(6):493-500.
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      133. Oksenberg JR, Baranzini SE, Sawcer S, Hauser SL. The genetics of multiple sclerosis: SNPs to pathways to pathogenesis. Nat Rev Genet. 2008 Jul; 9(7):516-26.
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      134. Hauser SL, Johnston SC. That vexing problem of compensation. Ann Neurol. 2008 Jun; 63(6):A11-2.
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      135. Johnston SC, Hauser SL. Transformative research. Ann Neurol. 2008 May; 63(5):A11-3.
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      136. Hauser SL, Johnston SC. Electronic medical records: does it take a village or a thousand points of light? Ann Neurol. 2008 Apr; 63(4):A13-4.
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      137. Claiborne Johnston S, Hauser SL. T2 clinical research: judgment day. Ann Neurol. 2008 Mar; 63(3):A15-6.
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      138. Hauser SL, Waubant E, Arnold DL, Vollmer T, Antel J, Fox RJ, Bar-Or A, Panzara M, Sarkar N, Agarwal S, Langer-Gould A, Smith CH. B-cell depletion with rituximab in relapsing-remitting multiple sclerosis. N Engl J Med. 2008 Feb 14; 358(7):676-88.
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      139. Oksenberg JR, Hauser SL. Neurogenetics in the Annals: dealing with complexity. Ann Neurol. 2008 Feb; 63(2):A11-4.
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      140. Johnston SC, Hauser SL. Clinical trials: rising costs limit innovation. Ann Neurol. 2007 Dec; 62(6):A6-7.
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      141. Begovich AB, Chang M, Caillier SJ, Lew D, Catanese JJ, Wang J, Hauser SL, Oksenberg JR. The autoimmune disease-associated IL12B and IL23R polymorphisms in multiple sclerosis. Hum Immunol. 2007 Nov; 68(11):934-7.
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      142. Hauser SL, Johnston SC. The upcoming meeting of the ANA. Ann Neurol. 2007 Sep; 62(3):A11.
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      143. McCauley JL, Kenealy SJ, Margulies EH, Schnetz-Boutaud N, Gregory SG, Hauser SL, Oksenberg JR, Pericak-Vance MA, Haines JL, Mortlock DP. SNPs in Multi-species Conserved Sequences (MCS) as useful markers in association studies: a practical approach. BMC Genomics. 2007; 8:266.
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      144. Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med. 2007 Aug 30; 357(9):851-62.
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      145. Gregory SG, Schmidt S, Seth P, Oksenberg JR, Hart J, Prokop A, Caillier SJ, Ban M, Goris A, Barcellos LF, Lincoln R, McCauley JL, Sawcer SJ, Compston DA, Dubois B, Hauser SL, Garcia-Blanco MA, Pericak-Vance MA, Haines JL. Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nat Genet. 2007 Sep; 39(9):1083-91.
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      146. Hauser SL, Johnston SC. Matriculating the next generation of clinician-scientists. Ann Neurol. 2007 Jul; 62(1):A10-1.
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      147. Kappos L, Bates D, Hartung HP, Havrdova E, Miller D, Polman CH, Ravnborg M, Hauser SL, Rudick RA, Weiner HL, O'Connor PW, King J, Radue EW, Yousry T, Major EO, Clifford DB. Natalizumab treatment for multiple sclerosis: recommendations for patient selection and monitoring. Lancet Neurol. 2007 May; 6(5):431-41.
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      148. Hauser SL, Johnston SC. Medical prizes: Lifetime achievement awards or engines for progress? Ann Neurol. 2007 May; 61(5):A11-2.
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      149. Johnston SC, Lowenstein DH, Ferriero DM, Messing RO, Oksenberg JR, Hauser SL. Early editorial manuscript screening versus obligate peer review: a randomized trial. Ann Neurol. 2007 Apr; 61(4):A10-2.
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      150. Yeo TW, De Jager PL, Gregory SG, Barcellos LF, Walton A, Goris A, Fenoglio C, Ban M, Taylor CJ, Goodman RS, Walsh E, Wolfish CS, Horton R, Traherne J, Beck S, Trowsdale J, Caillier SJ, Ivinson AJ, Green T, Pobywajlo S, Lander ES, Pericak-Vance MA, Haines JL, Daly MJ, Oksenberg JR, Hauser SL, Compston A, Hafler DA, Rioux JD, Sawcer S. A second major histocompatibility complex susceptibility locus for multiple sclerosis. Ann Neurol. 2007 Mar; 61(3):228-36.
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      151. Hauser SL, Johnston SC. Of ghosts and sirens: the subtlest lures of industry. Ann Neurol. 2007 Mar; 61(3):A11-2.
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      152. Johnston SC, Hauser SL. Marketing and drug costs: who is laughing and crying? Ann Neurol. 2007 Feb; 61(2):11A-12A.
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      153. Hensiek AE, Seaman SR, Barcellos LF, Oturai A, Eraksoi M, Cocco E, Vecsei L, Stewart G, Dubois B, Bellman-Strobl J, Leone M, Andersen O, Bencsik K, Booth D, Celius EG, Harbo HF, Hauser SL, Heard R, Hillert J, Myhr KM, Marrosu MG, Oksenberg JR, Rajda C, Sawcer SJ, Sørensen PS, Zipp F, Compston DA. Familial effects on the clinical course of multiple sclerosis. Neurology. 2007 Jan 30; 68(5):376-83.
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      154. Johnston SC, Hauser SL. A status report on neuroscience research, without grade inflation. Ann Neurol. 2006 Dec; 60(6):A9-11.
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      155. Barcellos LF, Kamdar BB, Ramsay PP, DeLoa C, Lincoln RR, Caillier S, Schmidt S, Haines JL, Pericak-Vance MA, Oksenberg JR, Hauser SL. Clustering of autoimmune diseases in families with a high-risk for multiple sclerosis: a descriptive study. Lancet Neurol. 2006 Nov; 5(11):924-31.
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      156. Hauser SL, Johnston SC. Recombinant therapeutics: from bench to bedside (if your health plan concurs). Ann Neurol. 2006 Nov; 60(5):10A-11A.
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      157. Hauser SL, Oksenberg JR. The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration. Neuron. 2006 Oct 5; 52(1):61-76.
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      158. Johnston SC, Hauser SL. Neurology and medical devices. Ann Neurol. 2006 Oct; 60(4):11A-2A.
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      159. Motsinger AA, Brassat D, Caillier SJ, Erlich HA, Walker K, Steiner LL, Barcellos LF, Pericak-Vance MA, Schmidt S, Gregory S, Hauser SL, Haines JL, Oksenberg JR, Ritchie MD. Complex gene-gene interactions in multiple sclerosis: a multifactorial approach reveals associations with inflammatory genes. Neurogenetics. 2007 Jan; 8(1):11-20.
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      160. Hauser SL, McArthur JC. Saving the clinician-scientist: report of the ANA long range planning committee. Ann Neurol. 2006 Sep; 60(3):278-85.
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      161. Barcellos LF, Sawcer S, Ramsay PP, Baranzini SE, Thomson G, Briggs F, Cree BC, Begovich AB, Villoslada P, Montalban X, Uccelli A, Savettieri G, Lincoln RR, DeLoa C, Haines JL, Pericak-Vance MA, Compston A, Hauser SL, Oksenberg JR. Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis. Hum Mol Genet. 2006 Sep 15; 15(18):2813-24.
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      162. Atzpodien J, Kirchner H, Rebmann U, Soder M, Gertenbach U, Siebels M, Roigas J, Raschke R, Salm S, Schwindl B, Müller SC, Hauser S, Leiber C, Huland E, Heinzer H, Siemer S, Metzner B, Heynemann H, Fornara P, Reitz M. Interleukin-2/interferon-alpha2a/13-retinoic acid-based chemoimmunotherapy in advanced renal cell carcinoma: results of a prospectively randomised trial of the German Cooperative Renal Carcinoma Chemoimmunotherapy Group (DGCIN). Br J Cancer. 2006 Aug 21; 95(4):463-9.
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      163. Kantarci OH, Barcellos LF, Atkinson EJ, Ramsay PP, Lincoln R, Achenbach SJ, De Andrade M, Hauser SL, Weinshenker BG. Men transmit MS more often to their children vs women: the Carter effect. Neurology. 2006 Jul 25; 67(2):305-10.
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      164. Johnston SC, Hauser SL. Basic and clinical research: what is the most appropriate weighting in a public investment portfolio? Ann Neurol. 2006 Jul; 60(1):9A-11A.
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      165. Hauser SL. Sleepiness in the elderly. Ann Neurol. 2006 Jun; 59(6):9A-10A.
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      166. Schmidt S, Pericak-Vance MA, Sawcer S, Barcellos LF, Hart J, Sims J, Prokop AM, van der Walt J, DeLoa C, Lincoln RR, Oksenberg JR, Compston A, Hauser SL, Haines JL, Gregory SG. Allelic association of sequence variants in the herpes virus entry mediator-B gene (PVRL2) with the severity of multiple sclerosis. Genes Immun. 2006 Jul; 7(5):384-92.
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      167. Burwick RM, Ramsay PP, Haines JL, Hauser SL, Oksenberg JR, Pericak-Vance MA, Schmidt S, Compston A, Sawcer S, Cittadella R, Savettieri G, Quattrone A, Polman CH, Uitdehaag BM, Zwemmer JN, Hawkins CP, Ollier WE, Weatherby S, Enzinger C, Fazekas F, Schmidt H, Schmidt R, Hillert J, Masterman T, Hogh P, Niino M, Kikuchi S, Maciel P, Santos M, Rio ME, Kwiecinski H, Zakrzewska-Pniewska B, Evangelou N, Palace J, Barcellos LF. APOE epsilon variation in multiple sclerosis susceptibility and disease severity: some answers. Neurology. 2006 May 9; 66(9):1373-83.
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      168. Hauser SL, Weiner HL. Natalizumab: immune effects and implications for therapy. Ann Neurol. 2006 May; 59(5):731-2.
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      169. Hauser SL. Low-grade central nervous system lymphoma: clarity through a hazy lens. Ann Neurol. 2006 May; 59(5):9A-10A.
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      170. Brassat D, Motsinger AA, Caillier SJ, Erlich HA, Walker K, Steiner LL, Cree BA, Barcellos LF, Pericak-Vance MA, Schmidt S, Gregory S, Hauser SL, Haines JL, Oksenberg JR, Ritchie MD. Multifactor dimensionality reduction reveals gene-gene interactions associated with multiple sclerosis susceptibility in African Americans. Genes Immun. 2006 Jun; 7(4):310-5.
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      171. Hauser SL. Multiple sclerosis: tip of the iceberg? Ann Neurol. 2006 Apr; 59(4):11A-12A.
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      172. von Büdingen HC, Menge T, Hauser SL, Genain CP. Restrictive and diversifying elements of the anti-myelin/oligodendrocyte glycoprotein antibody response in primate experimental allergic encephalomyelitis. Immunogenetics. 2006 Apr; 58(2-3):122-8.
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      173. Kenealy SJ, Herrel LA, Bradford Y, Schnetz-Boutaud N, Oksenberg JR, Hauser SL, Barcellos LF, Schmidt S, Gregory SG, Pericak-Vance MA, Haines JL. Examination of seven candidate regions for multiple sclerosis: strong evidence of linkage to chromosome 1q44. Genes Immun. 2006 Jan; 7(1):73-6.
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      174. Traherne JA, Barcellos LF, Sawcer SJ, Compston A, Ramsay PP, Hauser SL, Oksenberg JR, Trowsdale J. Association of the truncating splice site mutation in BTNL2 with multiple sclerosis is secondary to HLA-DRB1*15. Hum Mol Genet. 2006 Jan 1; 15(1):155-61.
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      175. Frohman EM, Stüve O, Havrdova E, Corboy J, Achiron A, Zivadinov R, Sorensen PS, Phillips JT, Weinshenker B, Hawker K, Hartung HP, Steinman L, Zamvil S, Cree BA, Hauser S, Weiner H, Racke MK, Filippi M. Therapeutic considerations for disease progression in multiple sclerosis: evidence, experience, and future expectations. Arch Neurol. 2005 Oct; 62(10):1519-30.
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      176. Fernald GH, Yeh RF, Hauser SL, Oksenberg JR, Baranzini SE. Mapping gene activity in complex disorders: Integration of expression and genomic scans for multiple sclerosis. J Neuroimmunol. 2005 Oct; 167(1-2):157-69.
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      177. Reich D, Patterson N, De Jager PL, McDonald GJ, Waliszewska A, Tandon A, Lincoln RR, DeLoa C, Fruhan SA, Cabre P, Bera O, Semana G, Kelly MA, Francis DA, Ardlie K, Khan O, Cree BA, Hauser SL, Oksenberg JR, Hafler DA. A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility. Nat Genet. 2005 Oct; 37(10):1113-8.
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      178. Frohman EM, Filippi M, Stuve O, Waxman SG, Corboy J, Phillips JT, Lucchinetti C, Wilken J, Karandikar N, Hemmer B, Monson N, De Keyser J, Hartung H, Steinman L, Oksenberg JR, Cree BA, Hauser S, Racke MK. Characterizing the mechanisms of progression in multiple sclerosis: evidence and new hypotheses for future directions. Arch Neurol. 2005 Sep; 62(9):1345-56.
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      179. Menge T, Lalive PH, von Büdingen HC, Cree B, Hauser SL, Genain CP. Antibody responses against galactocerebroside are potential stage-specific biomarkers in multiple sclerosis. J Allergy Clin Immunol. 2005 Aug; 116(2):453-9.
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      180. Sawcer S, Ban M, Maranian M, Yeo TW, Compston A, Kirby A, Daly MJ, De Jager PL, Walsh E, Lander ES, Rioux JD, Hafler DA, Ivinson A, Rimmler J, Gregory SG, Schmidt S, Pericak-Vance MA, Akesson E, Hillert J, Datta P, Oturai A, Ryder LP, Harbo HF, Spurkland A, Myhr KM, Laaksonen M, Booth D, Heard R, Stewart G, Lincoln R, Barcellos LF, Hauser SL, Oksenberg JR, Kenealy SJ, Haines JL. A high-density screen for linkage in multiple sclerosis. Am J Hum Genet. 2005 Sep; 77(3):454-67.
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      181. Oksenberg JR, Hauser SL. Genetics of multiple sclerosis. Neurol Clin. 2005 Feb; 23(1):61-75, vi.
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      182. Brassat D, Salemi G, Barcellos LF, McNeill G, Proia P, Hauser SL, Oksenberg JR, Savettieri G. The HLA locus and multiple sclerosis in Sicily. Neurology. 2005 Jan 25; 64(2):361-3.
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      183. Begovich AB, Caillier SJ, Alexander HC, Penko JM, Hauser SL, Barcellos LF, Oksenberg JR. The R620W polymorphism of the protein tyrosine phosphatase PTPN22 is not associated with multiple sclerosis. Am J Hum Genet. 2005 Jan; 76(1):184-7.
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      184. Cree BA, Khan O, Bourdette D, Goodin DS, Cohen JA, Marrie RA, Glidden D, Weinstock-Guttman B, Reich D, Patterson N, Haines JL, Pericak-Vance M, DeLoa C, Oksenberg JR, Hauser SL. Clinical characteristics of African Americans vs Caucasian Americans with multiple sclerosis. Neurology. 2004 Dec 14; 63(11):2039-45.
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      185. Hauser SL. An update on multiple sclerosis. J Neurol Sci. 2005 Feb 15; 228(2):193-4.
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      186. Kenealy SJ, Babron MC, Bradford Y, Schnetz-Boutaud N, Haines JL, Rimmler JB, Schmidt S, Pericak-Vance MA, Barcellos LF, Lincoln RR, Oksenberg JR, Hauser SL, Clanet M, Brassat D, Edan G, Yaouanq J, Semana G, Cournu-Rebeix I, Lyon-Caen O, Fontaine B. A second-generation genomic screen for multiple sclerosis. Am J Hum Genet. 2004 Dec; 75(6):1070-8.
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      187. Hauser SL. The shape of things to come. Neurology. 2004 Sep 28; 63(6):948-50.
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      188. Oksenberg JR, Hauser SL. Re: GAMES issue. J Neuroimmunol. 2004 Aug; 153(1-2):1-2.
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      189. von Büdingen HC, Hauser SL, Ouallet JC, Tanuma N, Menge T, Genain CP. Frontline: Epitope recognition on the myelin/oligodendrocyte glycoprotein differentially influences disease phenotype and antibody effector functions in autoimmune demyelination. Eur J Immunol. 2004 Aug; 34(8):2072-83.
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      191. Barcellos LF, Begovich AB, Reynolds RL, Caillier SJ, Brassat D, Schmidt S, Grams SE, Walker K, Steiner LL, Cree BA, Stillman A, Lincoln RR, Pericak-Vance MA, Haines JL, Erlich HA, Hauser SL, Oksenberg JR. Linkage and association with the NOS2A locus on chromosome 17q11 in multiple sclerosis. Ann Neurol. 2004 Jun; 55(6):793-800.
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      192. Patterson N, Hattangadi N, Lane B, Lohmueller KE, Hafler DA, Oksenberg JR, Hauser SL, Smith MW, O'Brien SJ, Altshuler D, Daly MJ, Reich D. Methods for high-density admixture mapping of disease genes. Am J Hum Genet. 2004 May; 74(5):979-1000.
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      193. Mirel DB, Barcellos LF, Wang J, Hauser SL, Oksenberg JR, Erlich HA. Analysis of IL4R haplotypes in predisposition to multiple sclerosis. Genes Immun. 2004 Mar; 5(2):138-41.
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      196. Caillier S, Barcellos LF, Baranzini SE, Swerdlin A, Lincoln RR, Steinman L, Martin E, Haines JL, Pericak-Vance M, Hauser SL, Oksenberg JR. Osteopontin polymorphisms and disease course in multiple sclerosis. Genes Immun. 2003 Jun; 4(4):312-5.
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      197. Rudick RA, Cookfair DL, Griffin J, Hauser S, Piantadosi S. Interferons in relapsing remitting multiple sclerosis. Lancet. 2003 May 24; 361(9371):1824; author reply 1824-5.
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      198. Sriram U, Barcellos LF, Villoslada P, Rio J, Baranzini SE, Caillier S, Stillman A, Hauser SL, Montalban X, Oksenberg JR. Pharmacogenomic analysis of interferon receptor polymorphisms in multiple sclerosis. Genes Immun. 2003 Mar; 4(2):147-52.
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      199. Barcellos LF, Oksenberg JR, Begovich AB, Martin ER, Schmidt S, Vittinghoff E, Goodin DS, Pelletier D, Lincoln RR, Bucher P, Swerdlin A, Pericak-Vance MA, Haines JL, Hauser SL. HLA-DR2 dose effect on susceptibility to multiple sclerosis and influence on disease course. Am J Hum Genet. 2003 Mar; 72(3):710-6.
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      200. Baranzini SE, Hauser SL. Large-scale gene-expression studies and the challenge of multiple sclerosis. Genome Biol. 2002 Sep 16; 3(10):reviews1027.
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      202. Stüve O, Cree BC, von Büdingen HC, Yousef S, Bowen JD, Genain CP, Hauser SL, Steinman L, Zamvil SS. Approved and future pharmacotherapy for multiple sclerosis. Neurologist. 2002 Sep; 8(5):290-301.
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      203. Villoslada P, Barcellos LF, Rio J, Begovich AB, Tintore M, Sastre-Garriga J, Baranzini SE, Casquero P, Hauser SL, Montalban X, Oksenberg JR. The HLA locus and multiple sclerosis in Spain. Role in disease susceptibility, clinical course and response to interferon-beta. J Neuroimmunol. 2002 Sep; 130(1-2):194-201.
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      204. von Büdingen HC, Hauser SL, Fuhrmann A, Nabavi CB, Lee JI, Genain CP. Molecular characterization of antibody specificities against myelin/oligodendrocyte glycoprotein in autoimmune demyelination. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):8207-12.
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      205. Cree BA, Goodin DS, Hauser SL. Neuromyelitis optica. Semin Neurol. 2002 Jun; 22(2):105-22.
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      206. Koehler NK, Genain CP, Giesser B, Hauser SL. The human T cell response to myelin oligodendrocyte glycoprotein: a multiple sclerosis family-based study. J Immunol. 2002 Jun 1; 168(11):5920-7.
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      207. Baranzini SE, Oksenberg JR, Hauser SL. New insights into the genetics of multiple sclerosis. J Rehabil Res Dev. 2002 Mar-Apr; 39(2):201-9.
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      208. Schmidt S, Barcellos LF, DeSombre K, Rimmler JB, Lincoln RR, Bucher P, Saunders AM, Lai E, Martin ER, Vance JM, Oksenberg JR, Hauser SL, Pericak-Vance MA, Haines JL. Association of polymorphisms in the apolipoprotein E region with susceptibility to and progression of multiple sclerosis. Am J Hum Genet. 2002 Mar; 70(3):708-17.
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      209. Patarroyo JC, Stuve O, Piskurich JF, Hauser SL, Oksenberg JR, Zamvil SS. Single nucleotide polymorphisms in MHC2TA, the gene encoding the MHC class II transactivator (CIITA). Genes Immun. 2002 Feb; 3(1):34-7.
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      210. Barcellos LF, Oksenberg JR, Green AJ, Bucher P, Rimmler JB, Schmidt S, Garcia ME, Lincoln RR, Pericak-Vance MA, Haines JL, Hauser SL. Genetic basis for clinical expression in multiple sclerosis. Brain. 2002 Jan; 125(Pt 1):150-8.
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      211. Villoslada P, Abel K, Heald N, Goertsches R, Hauser SL, Genain CP. Frequency, heterogeneity and encephalitogenicity of T cells specific for myelin oligodendrocyte glycoprotein in naive outbred primates. Eur J Immunol. 2001 Oct; 31(10):2942-50.
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      212. Pericak-Vance MA, Rimmler JB, Martin ER, Haines JL, Garcia ME, Oksenberg JR, Barcellos LF, Lincoln R, Goodkin DE, Hauser SL. Linkage and association analysis of chromosome 19q13 in multiple sclerosis. Neurogenetics. 2001 Oct; 3(4):195-201.
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      213. Genain CP, Hauser SL. Experimental allergic encephalomyelitis in the New World monkey Callithrix jacchus. Immunol Rev. 2001 Oct; 183:159-72.
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      214. Barcellos LF, Caillier S, Dragone L, Elder M, Vittinghoff E, Bucher P, Lincoln RR, Pericak-Vance M, Haines JL, Weiss A, Hauser SL, Oksenberg JR. PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients. Nat Genet. 2001 Sep; 29(1):23-4.
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      215. von Büdingen HC, Hauser SL, Nabavi CB, Genain CP. Characterization of the expressed immunoglobulin IGHV repertoire in the New World marmoset Callithrix jacchus. Immunogenetics. 2001 Sep; 53(7):557-63.
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      216. Green AJ, Bollen AW, Berger MS, Oksenberg JR, Hauser SL. Multiple sclerosis and oligodendroglioma. Mult Scler. 2001 Aug; 7(4):269-73.
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      217. Mohr DC, Goodkin DE, Islar J, Hauser SL, Genain CP. Treatment of depression is associated with suppression of nonspecific and antigen-specific T(H)1 responses in multiple sclerosis. Arch Neurol. 2001 Jul; 58(7):1081-6.
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      218. von Büdingen HC, Tanuma N, Villoslada P, Ouallet JC, Hauser SL, Genain CP. Immune responses against the myelin/oligodendrocyte glycoprotein in experimental autoimmune demyelination. J Clin Immunol. 2001 May; 21(3):155-70.
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      219. Green AJ, Barcellos LF, Rimmler JB, Garcia ME, Caillier S, Lincoln RR, Bucher P, Pericak-Vance MA, Haines JL, Hauser SL, Oksenberg JR. Sequence variation in the transforming growth factor-beta1 (TGFB1) gene and multiple sclerosis susceptibility. J Neuroimmunol. 2001 May 1; 116(1):116-24.
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      220. Oksenberg JR, Baranzini SE, Barcellos LF, Hauser SL. Multiple sclerosis: genomic rewards. J Neuroimmunol. 2001 Feb 15; 113(2):171-84.
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      221. Uccelli A, Giunti D, Mancardi G, Caroli F, Fiorone M, Seri M, Hauser SL, Genain CP. Characterization of the response to myelin basic protein in a non human primate model for multiple sclerosis. Eur J Immunol. 2001 Feb; 31(2):474-9.
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      222. Hauser S, Adelmant G, Sarraf P, Wright HM, Mueller E, Spiegelman BM. Degradation of the peroxisome proliferator-activated receptor gamma is linked to ligand-dependent activation. J Biol Chem. 2000 Jun 16; 275(24):18527-33.
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      223. Villoslada P, Hauser SL, Bartke I, Unger J, Heald N, Rosenberg D, Cheung SW, Mobley WC, Fisher S, Genain CP. Human nerve growth factor protects common marmosets against autoimmune encephalomyelitis by switching the balance of T helper cell type 1 and 2 cytokines within the central nervous system. J Exp Med. 2000 May 15; 191(10):1799-806.
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      224. Hauser SL, Oksenberg JR, Lincoln R, Garovoy J, Beck RW, Cole SR, Moke PS, Kip KE, Gal RL, Long DT. Interaction between HLA-DR2 and abnormal brain MRI in optic neuritis and early MS. Optic Neuritis Study Group. Neurology. 2000 May 9; 54(9):1859-61.
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      225. Barcellos LF, Schito AM, Rimmler JB, Vittinghoff E, Shih A, Lincoln R, Callier S, Elkins MK, Goodkin DE, Haines JL, Pericak-Vance MA, Hauser SL, Oksenberg JR. CC-chemokine receptor 5 polymorphism and age of onset in familial multiple sclerosis. Multiple Sclerosis Genetics Group. Immunogenetics. 2000 Apr; 51(4-5):281-8.
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      226. Wright HM, Clish CB, Mikami T, Hauser S, Yanagi K, Hiramatsu R, Serhan CN, Spiegelman BM. A synthetic antagonist for the peroxisome proliferator-activated receptor gamma inhibits adipocyte differentiation. J Biol Chem. 2000 Jan 21; 275(3):1873-7.
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      227. Fontaine B, Cournu I, Arnaud I, Babron MC, Eichenbaum-Voline S, Oksenberg JR, Pericak-Vance MA, Haines JL, Semama G, Liblau R, Lyon-Caen O, Clerget-Darpoux F, Clanet M, Hauser SL. Chromosome 17q22-q24 and multiple sclerosis genetic susceptibility. American-French Multiple Sclerosis Genetic Group. Genes Immun. 1999 Nov; 1(2):149-50.
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      228. Seboun E, Oksenberg JR, Rombos A, Usuku K, Goodkin DE, Lincoln RR, Wong M, Pham-Dinh D, Boesplug-Tanguy O, Carsique R, Fitoussi R, Gartioux C, Reyes C, Ribierre F, Faure S, Fizames C, Gyapay G, Weissenbach J, Dautigny A, Rimmler JB, Garcia ME, Pericak-Vance MA, Haines JL, Hauser SL. Linkage analysis of candidate myelin genes in familial multiple sclerosis. Neurogenetics. 1999 Sep; 2(3):155-62.
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      229. Diaz-Villoslada P, Shih A, Shao L, Genain CP, Hauser SL. Autoreactivity to myelin antigens: myelin/oligodendrocyte glycoprotein is a prevalent autoantigen. J Neuroimmunol. 1999 Sep 1; 99(1):36-43.
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      230. Raine CS, Cannella B, Hauser SL, Genain CP. Demyelination in primate autoimmune encephalomyelitis and acute multiple sclerosis lesions: a case for antigen-specific antibody mediation. Ann Neurol. 1999 Aug; 46(2):144-60.
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      231. Castillo G, Brun RP, Rosenfield JK, Hauser S, Park CW, Troy AE, Wright ME, Spiegelman BM. An adipogenic cofactor bound by the differentiation domain of PPARgamma. EMBO J. 1999 Jul 1; 18(13):3676-87.
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      232. Genain CP, Cannella B, Hauser SL, Raine CS. Identification of autoantibodies associated with myelin damage in multiple sclerosis. Nat Med. 1999 Feb; 5(2):170-5.
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      233. Oksenberg JR, Barcellos LF, Hauser SL. Genetic aspects of multiple sclerosis. Semin Neurol. 1999; 19(3):281-8.
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      234. Leppert D, Ford J, Stabler G, Grygar C, Lienert C, Huber S, Miller KM, Hauser SL, Kappos L. Matrix metalloproteinase-9 (gelatinase B) is selectively elevated in CSF during relapses and stable phases of multiple sclerosis. Brain. 1998 Dec; 121 ( Pt 12):2327-34.
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      235. Hauser S. Systemic lupus erythematosus (SLE) and neonatal morbidity and mortality. Aust N Z J Med. 1998 Aug; 28(4):482.
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      236. Haines JL, Terwedow HA, Burgess K, Pericak-Vance MA, Rimmler JB, Martin ER, Oksenberg JR, Lincoln R, Zhang DY, Banatao DR, Gatto N, Goodkin DE, Hauser SL. Linkage of the MHC to familial multiple sclerosis suggests genetic heterogeneity. The Multiple Sclerosis Genetics Group. Hum Mol Genet. 1998 Aug; 7(8):1229-34.
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      237. Pitt JJ, Hauser S. Transient 5-oxoprolinuria and high anion gap metabolic acidosis: clinical and biochemical findings in eleven subjects. Clin Chem. 1998 Jul; 44(7):1497-503.
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      238. Hauser SL. Multiple sclerosis: basic immunology. J Spinal Cord Med. 1998 Apr; 21(2):106-8.
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      239. Monte SM, Ghanbari K, Frey WH, Beheshti I, Averback P, Hauser SL, Ghanbari HA, Wands JR. Characterization of the AD7C-NTP cDNA expression in Alzheimer's disease and measurement of a 41-kD protein in cerebrospinal fluid. J Clin Invest. 1997 Dec 15; 100(12):3093-104.
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      240. Genain CP, Gritz L, Joshi N, Panicali D, Davis RL, Whitaker JN, Letvin NL, Hauser SL. Inhibition of allergic encephalomyelitis in marmosets by vaccination with recombinant vaccinia virus encoding for myelin basic protein. J Neuroimmunol. 1997 Nov; 79(2):119-28.
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      241. Oksenberg JR, Hauser SL. New insights into the immunogenetics of multiple sclerosis. Curr Opin Neurol. 1997 Jun; 10(3):181-5.
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      242. Genain CP, Hauser SL. Creation of a model for multiple sclerosis in Callithrix jacchus marmosets. J Mol Med (Berl). 1997 Mar; 75(3):187-97.
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      243. Uccelli A, Oksenberg JR, Jeong MC, Genain CP, Rombos T, Jaeger EE, Giunti D, Lanchbury JS, Hauser SL. Characterization of the TCRB chain repertoire in the New World monkey Callithrix jacchus. J Immunol. 1997 Feb 1; 158(3):1201-7.
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      244. Li Y, Uccelli A, Laxer KD, Jeong MC, Vinters HV, Tourtellotte WW, Hauser SL, Oksenberg JR. Local-clonal expansion of infiltrating T lymphocytes in chronic encephalitis of Rasmussen. J Immunol. 1997 Feb 1; 158(3):1428-37.
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      245. Genain CP, Abel K, Belmar N, Villinger F, Rosenberg DP, Linington C, Raine CS, Hauser SL. Late complications of immune deviation therapy in a nonhuman primate. Science. 1996 Dec 20; 274(5295):2054-7.
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      246. Leppert D, Waubant E, Bürk MR, Oksenberg JR, Hauser SL. Interferon beta-1b inhibits gelatinase secretion and in vitro migration of human T cells: a possible mechanism for treatment efficacy in multiple sclerosis. Ann Neurol. 1996 Dec; 40(6):846-52.
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      247. Usuku K, Joshi N, Hatem CJ, Wong MA, Stein MC, Hauser SL. Biased expression of T cell receptor genes characterizes activated T cells in multiple sclerosis cerebrospinal fluid. J Neurosci Res. 1996 Sep 15; 45(6):829-37.
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      248. Garcia-Merino A, Alper CA, Usuku K, Marcus-Bagley D, Lincoln R, Awdeh Z, Yunis EJ, Eisenbarth GS, Brink SJ, Hauser SL. Tumor necrosis factor (TNF) microsatellite haplotypes in relation to extended haplotypes, susceptibility to diseases associated with the major histocompatibility complex and TNF secretion. Hum Immunol. 1996 Sep 15; 50(1):11-21.
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      249. Haines JL, Ter-Minassian M, Bazyk A, Gusella JF, Kim DJ, Terwedow H, Pericak-Vance MA, Rimmler JB, Haynes CS, Roses AD, Lee A, Shaner B, Menold M, Seboun E, Fitoussi RP, Gartioux C, Reyes C, Ribierre F, Gyapay G, Weissenbach J, Hauser SL, Goodkin DE, Lincoln R, Usuku K, Oksenberg JR, et al. A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex. The Multiple Sclerosis Genetics Group. Nat Genet. 1996 Aug; 13(4):469-71.
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      250. Oksenberg JR, Seboun E, Hauser SL. Genetics of demyelinating diseases. Brain Pathol. 1996 Jul; 6(3):289-302.
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      251. Hesterkamp T, Hauser S, Lütcke H, Bukau B. Escherichia coli trigger factor is a prolyl isomerase that associates with nascent polypeptide chains. Proc Natl Acad Sci U S A. 1996 Apr 30; 93(9):4437-41.
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      252. Neilley LK, Goodin DS, Goodkin DE, Hauser SL. Side effect profile of interferon beta-1b in MS: results of an open label trial. Neurology. 1996 Feb; 46(2):552-4.
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      253. Xia M, Leppert D, Hauser SL, Sreedharan SP, Nelson PJ, Krensky AM, Goetzl EJ. Stimulus specificity of matrix metalloproteinase dependence of human T cell migration through a model basement membrane. J Immunol. 1996 Jan 1; 156(1):160-7.
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      254. Caplan LR, Achiron A, Hauser SL. What to tell patients with their first attack of multiple sclerosis. Eur Neurol. 1996; 36(4):183-90.
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      255. Genain CP, Nguyen MH, Letvin NL, Pearl R, Davis RL, Adelman M, Lees MB, Linington C, Hauser SL. Antibody facilitation of multiple sclerosis-like lesions in a nonhuman primate. J Clin Invest. 1995 Dec; 96(6):2966-74.
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      256. Hauser SL. Tumor necrosis factor: immunogenetics and disease. Ann Neurol. 1995 Nov; 38(5):702-4.
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      257. Leppert D, Hauser SL, Kishiyama JL, An S, Zeng L, Goetzl EJ. Stimulation of matrix metalloproteinase-dependent migration of T cells by eicosanoids. FASEB J. 1995 Nov; 9(14):1473-81.
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      258. Hauser SL. T-cell receptor genes. Germline polymorphisms and genetic susceptibility to demyelinating diseases. Ann N Y Acad Sci. 1995 Jul 7; 756:233-40.
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      259. Leppert D, Waubant E, Galardy R, Bunnett NW, Hauser SL. T cell gelatinases mediate basement membrane transmigration in vitro. J Immunol. 1995 May 1; 154(9):4379-89.
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      260. Genain CP, Roberts T, Davis RL, Nguyen MH, Uccelli A, Faulds D, Li Y, Hedgpeth J, Hauser SL. Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor. Proc Natl Acad Sci U S A. 1995 Apr 11; 92(8):3601-5.
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      261. Massacesi L, Genain CP, Lee-Parritz D, Letvin NL, Canfield D, Hauser SL. Active and passively induced experimental autoimmune encephalomyelitis in common marmosets: a new model for multiple sclerosis. Ann Neurol. 1995 Apr; 37(4):519-30.
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      262. Seibert K, Masferrer J, Zhang Y, Leahy K, Hauser S, Gierse J, Koboldt C, Anderson G, Bremer M, Gregory S, et al. Expression and selective inhibition of constitutive and inducible forms of cyclooxygenase. Adv Prostaglandin Thromboxane Leukot Res. 1995; 23:125-7.
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      263. Rozniecki JJ, Hauser SL, Stein M, Lincoln R, Theoharides TC. Elevated mast cell tryptase in cerebrospinal fluid of multiple sclerosis patients. Ann Neurol. 1995 Jan; 37(1):63-6.
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      264. Seibert K, Masferrer J, Zhang Y, Gregory S, Olson G, Hauser S, Leahy K, Perkins W, Isakson P. Mediation of inflammation by cyclooxygenase-2. Agents Actions Suppl. 1995; 46:41-50.
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      265. Calorini L, Simile M, Hauser S, Gattonicelli S. Reexpression of the major histocompatibility complex (MHC) class-I antigen h-2k(b) by m1 (b16-f10) murine melanoma-cells. Int J Oncol. 1994 Oct; 5(4):741-8.
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      266. Engstrom JW, Hauser SL. Future role of neurologists. West J Med. 1994 Sep; 161(3):331-4.
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      267. Genain CP, Lee-Parritz D, Nguyen MH, Massacesi L, Joshi N, Ferrante R, Hoffman K, Moseley M, Letvin NL, Hauser SL. In healthy primates, circulating autoreactive T cells mediate autoimmune disease. J Clin Invest. 1994 Sep; 94(3):1339-45.
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      268. Hauser SL. Prevention strategies for multiple sclerosis. Ann Neurol. 1994; 36 Suppl:S157-62.
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      269. Joshi N, Usuku K, Hauser SL. The T-cell response to myelin basic protein in familial multiple sclerosis: diversity of fine specificity, restricting elements, and T-cell receptor usage. Ann Neurol. 1993 Sep; 34(3):385-93.
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      270. Seboun E, Houghton L, Hatem CJ, Lincoln R, Hauser SL. Unusual organization of the human T-cell receptor beta-chain gene complex is linked to recombination hotspots. Proc Natl Acad Sci U S A. 1993 Jun 1; 90(11):5026-9.
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      271. Lev AA, Rosen DR, Kos C, Clifford E, Landes G, Hauser SL, Brown RH. Human ciliary neurotrophic factor: localization to the proximal region of the long arm of chromosome 11 and association with CA/GT dinucleotide repeat. Genomics. 1993 May; 16(2):539-41.
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      272. Weiner HL, Mackin GA, Orav EJ, Hafler DA, Dawson DM, LaPierre Y, Herndon R, Lehrich JR, Hauser SL, Turel A, et al. Intermittent cyclophosphamide pulse therapy in progressive multiple sclerosis: final report of the Northeast Cooperative Multiple Sclerosis Treatment Group. Neurology. 1993 May; 43(5):910-8.
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      273. Yu JS, Pandey JP, Massacesi L, Lincoln R, Usuku K, Seboun E, Hauser SL. Segregation of immunoglobulin heavy chain constant region genes in multiple sclerosis sibling pairs. J Neuroimmunol. 1993 Jan; 42(1):113-6.
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      274. Usuku K, Joshi N, Hatem CJ, Alper CA, Schoenfeld DA, Hauser SL. The human T-cell receptor beta-chain repertoire: longitudinal fluctuations and assessment in MHC matched populations. Immunogenetics. 1993; 38(3):193-8.
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      275. de la Monte SM, Volicer L, Hauser SL, Wands JR. Increased levels of neuronal thread protein in cerebrospinal fluid of patients with Alzheimer's disease. Ann Neurol. 1992 Dec; 32(6):733-42.
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      276. Hauser SL, Doolittle TH, Lopez-Bresnahan M, Shahani B, Schoenfeld D, Shih VE, Growdon J, Lehrich JR. An antispasticity effect of threonine in multiple sclerosis. Arch Neurol. 1992 Sep; 49(9):923-6.
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      277. Massacesi L, Joshi N, Lee-Parritz D, Rombos A, Letvin NL, Hauser SL. Experimental allergic encephalomyelitis in cynomolgus monkeys. Quantitation of T cell responses in peripheral blood. J Clin Invest. 1992 Aug; 90(2):399-404.
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      278. Seboun E, Joshi N, Hauser SL. Haplotypic origin of beta-chain genes expressed by human T-cell clones. Immunogenetics. 1992; 36(6):363-8.
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      279. Usuku K, Joshi N, Hauser SL. T-cell receptors: germline polymorphism and patterns of usage in demyelinating diseases. Crit Rev Immunol. 1992; 11(6):381-93.
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      280. Yu JS, Hayashi T, Seboun E, Sklar RM, Doolittle TH, Hauser SL. Fos RNA accumulation in multiple sclerosis white matter tissue. J Neurol Sci. 1991 Jun; 103(2):209-15.
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      281. Riskind PN, Massacesi L, Doolittle TH, Hauser SL. The role of prolactin in autoimmune demyelination: suppression of experimental allergic encephalomyelitis by bromocriptine. Ann Neurol. 1991 May; 29(5):542-7.
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      282. Hauser SL, Doolittle TH, Lincoln R, Brown RH, Dinarello CA. Cytokine accumulations in CSF of multiple sclerosis patients: frequent detection of interleukin-1 and tumor necrosis factor but not interleukin-6. Neurology. 1990 Nov; 40(11):1735-9.
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      283. Doolittle TH, Myers RH, Lehrich JR, Birnbaum G, Sheremata W, Franklin GM, Nelson LM, Hauser SL. Multiple sclerosis sibling pairs: clustered onset and familial predisposition. Neurology. 1990 Oct; 40(10):1546-52.
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      284. Kostyk SK, Kowall NW, Hauser SL. Substance P immunoreactive astrocytes are present in multiple sclerosis plaques. Brain Res. 1989 Dec 18; 504(2):284-8.
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      285. Seboun E, Robinson MA, Kindt TJ, Hauser SL. Insertion/deletion-related polymorphisms in the human T cell receptor beta gene complex. J Exp Med. 1989 Oct 1; 170(4):1263-70.
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      286. Sundblad A, Hauser S, Holmberg D, Cazenave PA, Coutinho A. Suppression of antibody responses to the acetylcholine receptor by natural antibodies. Eur J Immunol. 1989 Aug; 19(8):1425-30.
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      287. Ebener U, Hauser S, Wehner S, Kornhuber B. [Retrospective marker analyses performed with blood and bone marrow smears using an immunoenzyme procedure (alkaline phosphatase-anti-alkaline phosphatase technic)]. Klin Padiatr. 1989 Jul-Aug; 201(4):242-6.
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      288. Seboun E, Robinson MA, Doolittle TH, Ciulla TA, Kindt TJ, Hauser SL. A susceptibility locus for multiple sclerosis is linked to the T cell receptor beta chain complex. Cell. 1989 Jun 30; 57(7):1095-100.
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      289. Hauser SL, Fleischnick E, Weiner HL, Marcus D, Awdeh Z, Yunis EJ, Alper CA. Extended major histocompatibility complex haplotypes in patients with multiple sclerosis. Neurology. 1989 Feb; 39(2 Pt 1):275-7.
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      290. Shefer S, Salen G, Nguyen L, Batta AK, Packin V, Tint GS, Hauser S. Competitive inhibition of bile acid synthesis by endogenous cholestanol and sitosterol in sitosterolemia with xanthomatosis. Effect on cholesterol 7 alpha-hydroxylase. J Clin Invest. 1988 Dec; 82(6):1833-9.
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      291. Hayashi T, Morimoto C, Burks JS, Kerr C, Hauser SL. Dual-label immunocytochemistry of the active multiple sclerosis lesion: major histocompatibility complex and activation antigens. Ann Neurol. 1988 Oct; 24(4):523-31.
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      292. Hayashi T, Burks JS, Hauser SL. Expression and cellular localization of major histocompatibility complex antigens in active multiple sclerosis lesions. Ann N Y Acad Sci. 1988; 540:301-5.
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      293. Ciulla TA, Robinson MA, Seboun E, Doolittle TH, Hayashi T, Kindt TJ, Hauser SL. Molecular genotypes of the T-cell receptor beta chain in families with multiple sclerosis. Ann N Y Acad Sci. 1988; 540:271-6.
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      294. Hauser SL, Che M, Fallis RJ, Weiner HL. Immunoregulatory abnormalities induced by experimental reovirus infection: functional alterations in T-cell subpopulations. Clin Immunol Immunopathol. 1987 Dec; 45(3):481-90.
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      295. Henderson CE, Hauser SL, Huchet M, Dessi F, Hentati F, Taguchi T, Changeux JP, Fardeau M. Extracts of muscle biopsies from patients with spinal muscular atrophies inhibit neurite outgrowth from spinal neurons. Neurology. 1987 Aug; 37(8):1361-4.
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      296. Hauser SL, Cazenave PA, Lyon-Caen O, Taguchi T, Huchet M, Nuret H, Changeux JP, Henderson CE. Immunoblot analysis of circulating antibodies against muscle proteins in amyotrophic lateral sclerosis and other neurologic diseases. Neurology. 1986 Dec; 36(12):1614-8.
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      297. Lyon-Caen O, Jouvent R, Hauser S, Chaunu MP, Benoit N, Widlöcher D, Lhermitte F. Cognitive function in recent-onset demyelinating diseases. Arch Neurol. 1986 Nov; 43(11):1138-41.
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      298. Hauser SL, Aubert C, Burks JS, Kerr C, Lyon-Caen O, de The G, Brahic M. Analysis of human T-lymphotrophic virus sequences in multiple sclerosis tissue. Nature. 1986 Jul 10-16; 322(6075):176-7.
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      299. Hauser SL, Bhan AK, Gilles F, Kemp M, Kerr C, Weiner HL. Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesions. Ann Neurol. 1986 Jun; 19(6):578-87.
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      300. Brown RH, Hauser SL, Harrington H, Weiner HL. Failure of immunosuppression with a ten- to 14-day course of high-dose intravenous cyclophosphamide to alter the progression of amyotrophic lateral sclerosis. Arch Neurol. 1986 Apr; 43(4):383-4.
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      301. Hauser SL, Ault KA, Johnson D, Hoban C, Weiner HL. Increased IgG secretion by unstimulated mononuclear cells in active multiple sclerosis and functional assessment of the T8 subset. Clin Immunol Immunopathol. 1985 Dec; 37(3):312-23.
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      302. Hauser SL, Bahn AK, Che M, Gilles F, Weiner HL. Redistribution of Lyt-bearing T cells in acute murine experimental allergic encephalomyelitis: selective migration of Lyt-1 cells to the central nervous system is associated with a transient depletion of Lyt-1 cells in peripheral blood. J Immunol. 1984 Dec; 133(6):3037-42.
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      303. Hauser SL, Weiner HL, Bhan AK, Shapiro ME, Che M, Aldrich WR, Letvin NL. Lyt-1 cells mediate acute murine experimental allergic encephalomyelitis. J Immunol. 1984 Nov; 133(5):2288-90.
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      304. Shefer S, Hauser S, Salen G, Zaki FG, Bullock J, Salgado E, Shevitz J. Comparative effects of cholestanol and cholesterol on hepatic sterol and bile acid metabolism in the rat. J Clin Invest. 1984 Nov; 74(5):1773-81.
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      305. Hauser SL, Fosburg M, Kevy SV, Weiner HL. Lymphocytapheresis in chronic progressive multiple sclerosis: immunologic and clinical effects. Neurology. 1984 Jul; 34(7):922-6.
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      306. Tardieu M, Powers ML, Hafler DA, Hauser SL, Weiner HL. Autoimmunity following viral infection: demonstration of monoclonal antibodies against normal tissue following infection of mice with reovirus and demonstration of shared antigenicity between virus and lymphocytes. Eur J Immunol. 1984 Jun; 14(6):561-5.
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      307. Weiner HL, Hafler DA, Fallis RJ, Johnson D, Ault KA, Hauser SL. Altered blood T-cell subsets in patients with multiple sclerosis. J Neuroimmunol. 1984 Apr; 6(2):115-21.
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      308. Hauser SL, Weiner HL, Che M, Shapiro ME, Gilles F, Letvin NL. Prevention of experimental allergic encephalomyelitis (EAE) in the SJL/J mouse by whole body ultraviolet irradiation. J Immunol. 1984 Mar; 132(3):1276-81.
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      309. Weiner HL, Hafler DA, Fallis RJ, Johnson D, Ault KA, Hauser SL. T cell subsets in patients with multiple sclerosis. An overview. Ann N Y Acad Sci. 1984; 436:281-93.
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      310. Weiner HL, Hauser SL, Hafler DA, Fallis RJ, Lehrich JR, Dawson DM. The use of cyclophosphamide in the treatment of multiple sclerosis. Ann N Y Acad Sci. 1984; 436:373-81.
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      311. Hauser SL, Dawson DM, Lehrich JR, Beal MF, Kevy SV, Weiner HL. Immunosuppression and plasmapheresis in chronic progressive multiple sclerosis. Design of a clinical trial. Arch Neurol. 1983 Oct 21; 40(11):687-90.
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      312. Hauser SL, Bhan AK, Gilles FH, Hoban CJ, Reinherz EL, Schlossman SF, Weiner HL. Immunohistochemical staining of human brain with monoclonal antibodies that identify lymphocytes, monocytes, and the Ia antigen. J Neuroimmunol. 1983 Oct; 5(2):197-205.
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      313. Crary B, Hauser SL, Borysenko M, Kutz I, Hoban C, Ault KA, Weiner HL, Benson H. Epinephrine-induced changes in the distribution of lymphocyte subsets in peripheral blood of humans. J Immunol. 1983 Sep; 131(3):1178-81.
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      314. Hauser SL, Reinherz EL, Hoban CJ, Schlossman SF, Weiner HL. CSF cells in multiple sclerosis: monoclonal antibody analysis and relationship to peripheral blood T-cell subsets. Neurology. 1983 May; 33(5):575-9.
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      315. Hauser SL, Reinherz EL, Hoban CJ, Schlossman SF, Weiner HL. Immunoregulatory T-cells and lymphocytotoxic antibodies in active multiple sclerosis: weekly analysis over a six-month period. Ann Neurol. 1983 Apr; 13(4):418-25.
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      316. Hauser SL, Dawson DM, Lehrich JR, Beal MF, Kevy SV, Propper RD, Mills JA, Weiner HL. Intensive immunosuppression in progressive multiple sclerosis. A randomized, three-arm study of high-dose intravenous cyclophosphamide, plasma exchange, and ACTH. N Engl J Med. 1983 Jan 27; 308(4):173-80.
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      317. Weiner HL, Hauser SL. Immunoregulation in multiple sclerosis. Prog Brain Res. 1983; 59:339-43.
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      318. Weiner HL, Hauser SL. Neuroimmunology. II: Antigenic specificity of the nervous system. Ann Neurol. 1982 Dec; 12(6):499-509.
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      319. Hauser SL, Ropper AH, Perlo VP, Reinherz EL, Schlossman SF, Weiner HL. T-cell subsets in human autoimmune diseases. Neurology. 1982 Nov; 32(11):1320-1.
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      320. Hauser SL, Bresnan MJ, Reinherz EL, Weiner HL. Childhood multiple sclerosis: clinical features and demonstration of changes in T cell subsets with disease activity. Ann Neurol. 1982 May; 11(5):463-8.
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      321. Weiner HL, Hauser SL. Neuroimmunology I: Immunoregulation in neurological disease. Ann Neurol. 1982 May; 11(5):437-49.
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      322. Hauser SL, Weiner HL, Ault KA. Clonally restricted B cells in peripheral blood of multiple sclerosis patients: kappa/lambda staining patterns. Ann Neurol. 1982 Apr; 11(4):408-12.
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      323. Hauser SL, Fosburg M, Kevy S, Weiner HL. Plasmapheresis, lymphocytapheresis, and immunosuppressive drug therapy in multiple sclerosis. Prog Clin Biol Res. 1982; 106:239-54.
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      324. Hauser SL, Ault KA, Levin MJ, Garovoy MR, Weiner HL. Natural killer cell activity in multiple sclerosis. J Immunol. 1981 Sep; 127(3):1114-7.
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      325. Williams RS, Hauser SL, Purpura DP, DeLong GR, Swisher CN. Autism and mental retardation: neuropathologic studies performed in four retarded persons with autistic behavior. Arch Neurol. 1980 Dec; 37(12):749-53.
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      326. Reinherz EL, Weiner HL, Hauser SL, Cohen JA, Distaso JA, Schlossman SF. Loss of suppressor T cells in active multiple sclerosis. Analysis with monoclonal antibodies. N Engl J Med. 1980 Jul 17; 303(3):125-9.
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      327. Hauser SL, Weiner HL, Bresnan MJ, Ault KA. Lymphocyte capping in muscular dystrophy. Neurology. 1979 Oct; 29(10):1419-21.
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      328. Shefer S, Cheng FW, Dayal B, Hauser S, Tint GS, Salen G, Mosbach EH. A 25-hydroxylation pathway of cholic acid biosynthesis in man and rat. J Clin Invest. 1976 Apr; 57(4):897-903.
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      329. Hauser SL, DeLong GR, Rosman NP. Pneumographic findings in the infantile autism syndrome. A correlation with temporal lobe disease. Brain. 1975 Dec; 98(4):667-88.
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