Wilson Liao, MD
|School||UCSF School of Medicine|
|Address||2340 Sutter Street|
San Francisco CA 94115
|Harvard University||A.B.||1998||Biochemical Sciences|
|National Institutes of Health||Clinical Research Training Fellowship||2002||National Human Genome Research Institute|
|Harvard University||M.D.||2003||School of Medicine|
|University of California San Francisco||Clinical Residency||2007||Department of Dermatology|
|University of California San Francisco||Postdoctoral Fellowship||2009||Human Genetics|
Dr. Liao serves as Director of the UCSF Psoriasis and Skin Treatment Center and is deeply engaged in patient care, clinical trials, and basic science research. The Liao laboratory studies the genetics and environmental triggers of psoriasis, a common immune-mediated skin disease. Dr. Liao directs the UCSF Psoriasis Research Initiative and Biobank with over 1,000 subjects, which is used for genetic and translational research studies. The Liao lab has contributed to the publication of the first two genome-wide association studies in psoriasis and has helped identify over 20 additional risk variants, including a deletion of the late cornified envelope genes, common variants in UBE2L3 and SH2B3, copy number changes in KIR3DS1 and NKG2C, and rare variants in IFIH1 and CARD14. His lab has identified a genetic similarity between individuals with psoriasis and individuals who have robust immunity against HIV-1. This has highlighted the role of antiviral immune responses in contributing to autoimmune susceptibility. Current projects include the identification of psoriasis causal variants through high resolution genetic mapping and functional genomics, elucidation of psoriasis pathways through novel transcriptional and immunoprofiling technologies, and determination of the role of the microbiome in psoriatic inflammation. We welcome inquiries about collaborations and student participation in research.
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