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John Witte, PhD, MS

TitleProfessor
SchoolUCSF School of Medicine
DepartmentEpidemiology & Biostatistics
Address1450 3rd Street
San Francisco CA 94158
Phone415-502-6882
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    Collapse Research 
    Collapse Research Activities and Funding
    Genome-wide Pleiotropy Scan across Multiple Cancers
    NIH/NCI R01CA201358Aug 1, 2016 - Jul 31, 2020
    Role: Principal Investigator
    Genomewide Association Study of Prostate Cancer
    NIH/NCI U01CA127298Sep 18, 2008 - Aug 31, 2014
    Role: Principal Investigator
    Training in Molecular& Genetic Epidemiology of Cancer
    NIH/NCI R25CA112355Dec 1, 2004 - Aug 31, 2019
    Role: Principal Investigator
    Androgen Pathway Factors and Prostate Cancer
    NIH/NCI R01CA094211Jul 15, 2002 - Jun 30, 2007
    Role: Principal Investigator
    Computational Genomic Epidemiology of Cancer (CoGEC) Training Program
    NIH/NCI R25CA094186Dec 1, 2001 - Jul 31, 2017
    Role: Co-Principal Investigator
    Genetic Epidemiology of Prostate Cancer Risk and Progression
    NIH/NCI R01CA088164Sep 1, 2000 - Jun 30, 2016
    Role: Principal Investigator
    Pharmacogenomics of Membrane Transporters
    NIH U19GM061390Apr 1, 2000 - Jun 30, 2015
    Role: Co-Investigator
    Cancer Center Support Grant
    NIH/NCI P30CA082103Aug 5, 1999 - May 31, 2018
    Role: Co-Investigator
    HIERARCHICAL MODELING IN CANCER RESEARCH
    NIH/NCI R29CA073270Jul 1, 1996 - Jun 30, 2001
    Role: Principal Investigator
    Human Genetic Analysis Resource
    NIH P41RR003655Sep 30, 1987 - Jul 31, 2012
    Role: Co-Investigator

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    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Zhang C, de Smith AJ, Smirnov IV, Wiencke JK, Wiemels JL, Witte JS, Walsh KM. Non-additive and epistatic effects of HLA polymorphisms contributing to risk of adult glioma. J Neurooncol. 2017 Jul 18. PMID: 28721485.
      View in: PubMed
    2. Mosley JD, Shoemaker MB, Wells QS, Darbar D, Shaffer CM, Edwards TL, Bastarache L, McCarty CA, Thompson W, Chute CG, Jarvik GP, Crosslin DR, Larson EB, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Linneman JG, Witte J, Denny JC, Roden DM. Investigating the Genetic Architecture of the PR Interval Using Clinical Phenotypes. Circ Cardiovasc Genet. 2017 Apr; 10(2). PMID: 28416512.
      View in: PubMed
    3. Hoffman JD, Graff RE, Emami NC, Tai CG, Passarelli MN, Hu D, Huntsman S, Hadley D, Leong L, Majumdar A, Zaitlen N, Ziv E, Witte JS. Cis-eQTL-based trans-ethnic meta-analysis reveals novel genes associated with breast cancer risk. PLoS Genet. 2017 Mar; 13(3):e1006690. PMID: 28362817.
      View in: PubMed
    4. Hoffmann TJ, Passarelli MN, Graff RE, Emami NC, Sakoda LC, Jorgenson E, Habel LA, Shan J, Ranatunga DK, Quesenberry CP, Chao CR, Ghai NR, Aaronson D, Presti J, Nordström T, Wang Z, Berndt SI, Chanock SJ, Mosley JD, Klein RJ, Middha M, Lilja H, Melander O, Kvale MN, Kwok PY, Schaefer C, Risch N, Van Den Eeden SK, Witte JS. Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer. Nat Commun. 2017 Jan 31; 8:14248. PMID: 28139693.
      View in: PubMed
    5. Emami NC, Leong L, Wan E, Van Blarigan EL, Cooperberg MR, Tenggara I, Carroll PR, Chan JM, Witte J, Simko JP. Tissue Sources for Accurate Measurement of Germline DNA Genotypes in Prostate Cancer Patients Treated With Radical Prostatectomy. Prostate. 2017 Mar; 77(4):425-434. PMID: 27900799.
      View in: PubMed
    6. Karami S, Han Y, Pande M, Cheng I, Rudd J, Pierce BL, Nutter EL, Schumacher FR, Kote-Jarai Z, Lindstrom S, Witte JS, Fang S, Han J, Kraft P, Hunter DJ, Song F, Hung RJ, McKay J, Gruber SB, Chanock SJ, Risch A, Shen H, Haiman CA, Boardman L, Ulrich CM, Casey G, Peters U, Amin Al Olama A, Berchuck A, Berndt SI, Bezieau S, Brennan P, Brenner H, Brinton L, Caporaso N, Chan AT, Chang-Claude J, Christiani DC, Cunningham JM, Easton D, Eeles RA, Eisen T, Gala M, Gallinger SJ, Gayther SA, Goode EL, Grönberg H, Henderson BE, Houlston R, Joshi AD, Küry S, Landi MT, Le Marchand L, Muir K, Newcomb PA, Permuth-Wey J, Pharoah P, Phelan C, Potter JD, Ramus SJ, Risch H, Schildkraut J, Slattery ML, Song H, Wentzensen N, White E, Wiklund F, Zanke BW, Sellers TA, Zheng W, Chatterjee N, Amos CI, Doherty JA. Telomere structure and maintenance gene variants and risk of five cancer types. Int J Cancer. 2016 Dec 15; 139(12):2655-2670. PMID: 27459707.
      View in: PubMed
    7. Marini NJ, Yang W, Asrani K, Witte JS, Rine J, Lammer EJ, Shaw GM. Sequence variation in folate pathway genes and risks of human cleft lip with or without cleft palate. Am J Med Genet A. 2016 Nov; 170(11):2777-2787. PMID: 27604992.
      View in: PubMed
    8. Zhou K, Yee SW, Seiser EL, van Leeuwen N, Tavendale R, Bennett AJ, Groves CJ, Coleman RL, van der Heijden AA, Beulens JW, de Keyser CE, Zaharenko L, Rotroff DM, Out M, Jablonski KA, Chen L, Javorský M, Židzik J, Levin AM, Williams LK, Dujic T, Semiz S, Kubo M, Chien HC, Maeda S, Witte J, Wu L, Tkác I, Kooy A, van Schaik RH, Stehouwer CD, Logie L, Sutherland C, Klovins J, Pirags V, Hofman A, Stricker BH, Motsinger-Reif AA, Wagner MJ, Innocenti F, Hart LM, Holman RR, McCarthy MI, Hedderson MM, Palmer CN, Florez JC, Giacomini KM, Pearson ER, et al. Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin. Nat Genet. 2016 Sep; 48(9):1055-1059. PMID: 27500523; PMCID: PMC5007158.
    9. Brenner DR, Brennan P, Boffetta P, Amos CI, Spitz MR, Chen C, Goodman G, Heinrich J, Bickeböller H, Rosenberger A, Risch A, Muley T, McLaughlin JR, Benhamou S, Bouchardy C, Lewinger JP, Witte JS, Chen G, Bull S, Hung RJ. Erratum to: Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls. Hum Genet. 2016 Aug; 135(8):963. PMID: 27264937.
      View in: PubMed
    10. Lee SA, Mefford JA, Huang Y, Witte J, Martin JN, Haas DW, Mclaren PJ, Mushiroda T, Kubo M, Byakwaga H, Hunt PW, Kroetz DL, et al. Host genetic predictors of the kynurenine pathway of tryptophan catabolism among treated HIV-infected Ugandans. AIDS. 2016 Jul 17; 30(11):1807-15. PMID: 27088321; PMCID: PMC4925250 [Available on 07/17/17].
    11. Majumdar A, Haldar T, Witte J. Determining Which Phenotypes Underlie a Pleiotropic Signal. Genet Epidemiol. 2016 07; 40(5):366-81. PMID: 27238845; PMCID: PMC4929010.
    12. Sapru A, Liu KD, Wiemels J, Hansen H, Pawlikowska L, Poon A, Jorgenson E, Witte JS, Calfee CS, Ware LB, Matthay MA. Association of common genetic variation in the protein C pathway genes with clinical outcomes in acute respiratory distress syndrome. Crit Care. 2016 May 23; 20(1):151. PMID: 27215212; PMCID: PMC4876559.
    13. Uricchio LH, Zaitlen NA, Ye CJ, Witte JS, Hernandez RD. Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants. Genome Res. 2016 07; 26(7):863-73. PMID: 27197206; PMCID: PMC4937562.
    14. Mosley JD, Witte JS, Larkin EK, Bastarache L, Shaffer CM, Karnes JH, Stein CM, Phillips E, Hebbring SJ, Brilliant MH, Mayer J, Ye Z, Roden DM, Denny JC. Identifying genetically driven clinical phenotypes using linear mixed models. Nat Commun. 2016 Apr 25; 7:11433. PMID: 27109359; PMCID: PMC4848547.
    15. Carmichael SL, Yang W, Ma C, Roberts E, Kegley S, English P, Lammer EJ, Witte JS, Shaw GM. Joint effects of genetic variants and residential proximity to pesticide applications on hypospadias risk. Birth Defects Res A Clin Mol Teratol. 2016 Aug; 106(8):653-8. PMID: 27098078; PMCID: PMC4983249 [Available on 08/01/17].
    16. Li M, Li J, He Z, Lu Q, Witte JS, Macleod SL, Hobbs CA, Cleves MA. Testing Allele Transmission of an SNP Set Using a Family-Based Generalized Genetic Random Field Method. Genet Epidemiol. 2016 May; 40(4):341-51. PMID: 27061818.
      View in: PubMed
    17. Gusev A, Shi H, Kichaev G, Pomerantz M, Li F, Long HW, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Zheng W, Pettaway CA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, John EM, Murphy AB, Signorello LB, Carpten J, Leske MC, Wu SY, Hennis AJ, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Witte JS, Casey G, Kaggwa S, Cook MB, Stram DO, Blot WJ, Eeles RA, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Southey MC, Fitzgerald LM, Gronberg H, Wiklund F, Aly M, Henderson BE, Schleutker J, Wahlfors T, Tammela TL, Nordestgaard BG, Key TJ, Travis RC, Neal DE, Donovan JL, Hamdy FC, Pharoah P, Pashayan N, Khaw KT, Stanford JL, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Wokolorczyk D, Kluzniak W, Cannon-Albright L, Teerlink C, Brenner H, Dieffenbach AK, Arndt V, Park JY, Sellers TA, Lin HY, Slavov C, Kaneva R, Mitev V, Batra J, Spurdle A, Clements JA, Teixeira MR, Pandha H, Michael A, Paulo P, Maia S, Kierzek A, Conti DV, Albanes D, Berg C, Berndt SI, Campa D, Crawford ED, Diver WR, Gapstur SM, Gaziano JM, Giovannucci E, Hoover R, Hunter DJ, Johansson M, Kraft P, Le Marchand L, Lindström S, Navarro C, Overvad K, Riboli E, Siddiq A, Stevens VL, Trichopoulos D, Vineis P, Yeager M, Trynka G, Raychaudhuri S, Schumacher FR, Price AL, Freedman ML, Haiman CA, Pasaniuc B. Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation. Nat Commun. 2016 Apr 07; 7:10979. PMID: 27052111; PMCID: PMC4829663.
    18. Lindquist KJ, Paris PL, Hoffmann TJ, Cardin NJ, Kazma R, Mefford JA, Simko JP, Ngo V, Chen Y, Levin AM, Chitale D, Helfand BT, Catalona WJ, Rybicki BA, Witte JS. Mutational Landscape of Aggressive Prostate Tumors in African American Men. Cancer Res. 2016 04 01; 76(7):1860-8. PMID: 26921337; PMCID: PMC4772140 [Available on 04/01/17].
    19. Han Y, Rand KA, Hazelett DJ, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Stanford JL, Zheng W, Schumacher FR, Berndt SI, Wang Z, Xu J, Rohland N, Reich D, Tandon A, Pasaniuc B, Allen A, Quinque D, Mallick S, Notani D, Rosenfeld MG, Jayani RS, Kolb S, Gapstur SM, Stevens VL, Pettaway CA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, John EM, Murphy AB, Signorello LB, Carpten J, Leske MC, Wu SY, Hennis AJ, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Zheng SL, Witte JS, Casey G, Lubwama A, Pooler LC, Sheng X, Coetzee GA, Cook MB, Chanock SJ, Stram DO, Watya S, Blot WJ, Conti DV, Henderson BE, Haiman CA. Prostate Cancer Susceptibility in Men of African Ancestry at 8q24. J Natl Cancer Inst. 2016 Jul; 108(7). PMID: 26823525; PMCID: PMC4948565 [Available on 07/01/17].
    20. Scarbrough PM, Weber RP, Iversen ES, Brhane Y, Amos CI, Kraft P, Hung RJ, Sellers TA, Witte JS, Pharoah P, Henderson BE, Gruber SB, Hunter DJ, Garber JE, Joshi AD, McDonnell K, Easton DF, Eeles R, Kote-Jarai Z, Muir K, Doherty JA, Schildkraut JM. A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast, and Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2016 Jan; 25(1):193-200. PMID: 26637267; PMCID: PMC4713268.
    21. Majumdar A, Witte JS, Ghosh S. Semiparametric Allelic Tests for Mapping Multiple Phenotypes: Binomial Regression and Mahalanobis Distance. Genet Epidemiol. 2015 Dec; 39(8):635-50. PMID: 26493781; PMCID: PMC4958458.
    22. Hoffmann TJ, Witte JS. Strategies for Imputing and Analyzing Rare Variants in Association Studies. Trends Genet. 2015 Oct; 31(10):556-63. PMID: 26450338; PMCID: PMC4600126 [Available on 10/01/16].
    23. Kwok B, Hall JM, Witte JS, Xu Y, Reddy P, Lin K, Flamholz R, Dabbas B, Yung A, Al-Hafidh J, Balmert E, Vaupel C, El Hader C, McGinniss MJ, Nahas SA, Kines J, Bejar R. MDS-associated somatic mutations and clonal hematopoiesis are common in idiopathic cytopenias of undetermined significance. Blood. 2015 Nov 19; 126(21):2355-61. PMID: 26429975; PMCID: PMC4653764.
    24. Hung RJ, Ulrich CM, Goode EL, Brhane Y, Muir K, Chan AT, Marchand LL, Schildkraut J, Witte JS, Eeles R, Boffetta P, Spitz MR, Poirier JG, Rider DN, Fridley BL, Chen Z, Haiman C, Schumacher F, Easton DF, Landi MT, Brennan P, Houlston R, Christiani DC, Field JK, Bickeböller H, Risch A, Kote-Jarai Z, Wiklund F, Grönberg H, Chanock S, Berndt SI, Kraft P, Lindström S, Al Olama AA, Song H, Phelan C, Wentzensen N, Peters U, Slattery ML, Sellers TA, Casey G, Gruber SB, Hunter DJ, Amos CI, Henderson B. Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer. J Natl Cancer Inst. 2015 Nov; 107(11). PMID: 26319099; PMCID: PMC4675100 [Available on 11/01/16].
    25. Han Y, Hazelett DJ, Wiklund F, Schumacher FR, Stram DO, Berndt SI, Wang Z, Rand KA, Hoover RN, Machiela MJ, Yeager M, Burdette L, Chung CC, Hutchinson A, Yu K, Xu J, Travis RC, Key TJ, Siddiq A, Canzian F, Takahashi A, Kubo M, Stanford JL, Kolb S, Gapstur SM, Diver WR, Stevens VL, Strom SS, Pettaway CA, Al Olama AA, Kote-Jarai Z, Eeles RA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, Isaacs WB, Chen C, Lindstrom S, Le Marchand L, Giovannucci EL, Pomerantz M, Long H, Li F, Ma J, Stampfer M, John EM, Ingles SA, Kittles RA, Murphy AB, Blot WJ, Signorello LB, Zheng W, Albanes D, Virtamo J, Weinstein S, Nemesure B, Carpten J, Leske MC, Wu SY, Hennis AJ, Rybicki BA, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Zheng SL, Witte JS, Casey G, Riboli E, Li Q, Freedman ML, Hunter DJ, Gronberg H, Cook MB, Nakagawa H, Kraft P, Chanock SJ, Easton DF, Henderson BE, Coetzee GA, Conti DV, Haiman CA. Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions. Hum Mol Genet. 2015 Oct 1; 24(19):5603-18. PMID: 26162851; PMCID: PMC4572069 [Available on 10/01/16].
    26. Hoffmann TJ, Van Den Eeden SK, Sakoda LC, Jorgenson E, Habel LA, Graff RE, Passarelli MN, Cario CL, Emami NC, Chao CR, Ghai NR, Shan J, Ranatunga DK, Quesenberry CP, Aaronson D, Presti J, Wang Z, Berndt SI, Chanock SJ, McDonnell SK, French AJ, Schaid DJ, Thibodeau SN, Li Q, Freedman ML, Penney KL, Mucci LA, Haiman CA, Henderson BE, Seminara D, Kvale MN, Kwok PY, Schaefer C, Risch N, Witte JS. A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. Cancer Discov. 2015 Aug; 5(8):878-91. PMID: 26034056; PMCID: PMC4527942.
    27. Webber DM, MacLeod SL, Bamshad MJ, Shaw GM, Finnell RH, Shete SS, Witte JS, Erickson SW, Murphy LD, Hobbs C. Developments in our understanding of the genetic basis of birth defects. Birth Defects Res A Clin Mol Teratol. 2015 Aug; 103(8):680-91. PMID: 26033863; PMCID: PMC4537658.
    28. Tai CG, Graff RE, Liu J, Passarelli MN, Mefford JA, Shaw GM, Hoffmann TJ, Witte JS. Detecting gene-environment interactions in human birth defects: Study designs and statistical methods. Birth Defects Res A Clin Mol Teratol. 2015 Aug; 103(8):692-702. PMID: 26010994; PMCID: PMC4537677.
    29. Virlogeux V, Graff RE, Hoffmann TJ, Witte JS. Replication and heritability of prostate cancer risk variants: impact of population-specific factors. Cancer Epidemiol Biomarkers Prev. 2015 Jun; 24(6):938-43. PMID: 25809866.
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    30. Helfand BT, Roehl KA, Cooper PR, McGuire BB, Fitzgerald LM, Cancel-Tassin G, Cornu JN, Bauer S, Van Blarigan EL, Chen X, Duggan D, Ostrander EA, Gwo-Shu M, Zhang ZF, Chang SC, Jeong S, Fontham ET, Smith G, Mohler JL, Berndt SI, McDonnell SK, Kittles R, Rybicki BA, Freedman M, Kantoff PW, Pomerantz M, Breyer JP, Smith JR, Rebbeck TR, Mercola D, Isaacs WB, Wiklund F, Cussenot O, Thibodeau SN, Schaid DJ, Cannon-Albright L, Cooney KA, Chanock SJ, Stanford JL, Chan JM, Witte J, Xu J, Bensen JT, Taylor JA, Catalona WJ. Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases. Hum Genet. 2015 Apr; 134(4):439-50. PMID: 25715684; PMCID: PMC4586077.
    31. Hoffmann TJ, Sakoda LC, Shen L, Jorgenson E, Habel LA, Liu J, Kvale MN, Asgari MM, Banda Y, Corley D, Kushi LH, Quesenberry CP, Schaefer C, Van Den Eeden SK, Risch N, Witte JS. Imputation of the rare HOXB13 G84E mutation and cancer risk in a large population-based cohort. PLoS Genet. 2015 Jan; 11(1):e1004930. PMID: 25629170; PMCID: PMC4309593.
    32. Choudhry S, Baskin LS, Lammer EJ, Witte JS, Dasgupta S, Ma C, Surampalli A, Shen J, Shaw GM, Carmichael SL. Genetic polymorphisms in ESR1 and ESR2 genes, and risk of hypospadias in a multiethnic study population. J Urol. 2015 May; 193(5):1625-31. PMID: 25463985.
      View in: PubMed
    33. Uricchio LH, Torres R, Witte JS, Hernandez RD. Population genetic simulations of complex phenotypes with implications for rare variant association tests. Genet Epidemiol. 2015 Jan; 39(1):35-44. PMID: 25417809; PMCID: PMC4270825.
    34. Zaitlen N, Pasaniuc B, Sankararaman S, Bhatia G, Zhang J, Gusev A, Young T, Tandon A, Pollack S, Vilhjálmsson BJ, Assimes TL, Berndt SI, Blot WJ, Chanock S, Franceschini N, Goodman PG, He J, Hennis AJ, Hsing A, Ingles SA, Isaacs W, Kittles RA, Klein EA, Lange LA, Nemesure B, Patterson N, Reich D, Rybicki BA, Stanford JL, Stevens VL, Strom SS, Whitsel EA, Witte JS, Xu J, Haiman C, Wilson JG, Kooperberg C, Stram D, Reiner AP, Tang H, Price AL. Leveraging population admixture to characterize the heritability of complex traits. Nat Genet. 2014 Dec; 46(12):1356-62. PMID: 25383972; PMCID: PMC4244251.
    35. Chen HS, Hutter CM, Mechanic LE, Amos CI, Bafna V, Hauser ER, Hernandez RD, Li C, Liberles DA, McAllister K, Moore JH, Paltoo DN, Papanicolaou GJ, Peng B, Ritchie MD, Rosenfeld G, Witte JS, Gillanders EM, Feuer EJ. Genetic simulation tools for post-genome wide association studies of complex diseases. Genet Epidemiol. 2015 Jan; 39(1):11-9. PMID: 25371374; PMCID: PMC4270837 [Available on 01/01/16].
    36. Weng PH, Huang YL, Page JH, Chen JH, Xu J, Koutros S, Berndt S, Chanock S, Yeager M, Witte JS, Eeles RA, Easton DF, Neal DE, Donovan J, Hamdy FC, Muir KR, Giles G, Severi G, Smith JR, Balistreri CR, Shui IM, Chen YC. Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis. PLoS One. 2014; 9(10):e110569. PMID: 25360682; PMCID: PMC4215920.
    37. Gerstenberger JP, Bauer SR, Van Blarigan EL, Sosa E, Song X, Witte JS, Carroll PR, Chan JM. Selenoprotein and antioxidant genes and the risk of high-grade prostate cancer and prostate cancer recurrence. Prostate. 2015 Jan; 75(1):60-9. PMID: 25284284; PMCID: PMC4257852.
    38. Bhatia G, Tandon A, Patterson N, Aldrich MC, Ambrosone CB, Amos C, Bandera EV, Berndt SI, Bernstein L, Blot WJ, Bock CH, Caporaso N, Casey G, Deming SL, Diver WR, Gapstur SM, Gillanders EM, Harris CC, Henderson BE, Ingles SA, Isaacs W, De Jager PL, John EM, Kittles RA, Larkin E, McNeill LH, Millikan RC, Murphy A, Neslund-Dudas C, Nyante S, Press MF, Rodriguez-Gil JL, Rybicki BA, Schwartz AG, Signorello LB, Spitz M, Strom SS, Tucker MA, Wiencke JK, Witte JS, Wu X, Yamamura Y, Zanetti KA, Zheng W, Ziegler RG, Chanock SJ, Haiman CA, Reich D, Price AL. Genome-wide scan of 29,141 African Americans finds no evidence of directional selection since admixture. Am J Hum Genet. 2014 Oct 02; 95(4):437-44. PMID: 25242497; PMCID: PMC4185117.
    39. Witte JS, Visscher PM, Wray NR. The contribution of genetic variants to disease depends on the ruler. Nat Rev Genet. 2014 11; 15(11):765-76. PMID: 25223781; PMCID: PMC4412738.
    40. Al Olama AA, Kote-Jarai Z, Berndt SI, Conti DV, Schumacher F, Han Y, Benlloch S, Hazelett DJ, Wang Z, Saunders E, Leongamornlert D, Lindstrom S, Jugurnauth-Little S, Dadaev T, Tymrakiewicz M, Stram DO, Rand K, Wan P, Stram A, Sheng X, Pooler LC, Park K, Xia L, Tyrer J, Kolonel LN, Le Marchand L, Hoover RN, Machiela MJ, Yeager M, Burdette L, Chung CC, Hutchinson A, Yu K, Goh C, Ahmed M, Govindasami K, Guy M, Tammela TL, Auvinen A, Wahlfors T, Schleutker J, Visakorpi T, Leinonen KA, Xu J, Aly M, Donovan J, Travis RC, Key TJ, Siddiq A, Canzian F, Khaw KT, Takahashi A, Kubo M, Pharoah P, Pashayan N, Weischer M, Nordestgaard BG, Nielsen SF, Klarskov P, Røder MA, Iversen P, Thibodeau SN, McDonnell SK, Schaid DJ, Stanford JL, Kolb S, Holt S, Knudsen B, Coll AH, Gapstur SM, Diver WR, Stevens VL, Maier C, Luedeke M, Herkommer K, Rinckleb AE, Strom SS, Pettaway C, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, Cannon-Albright L, Cybulski C, Wokolorczyk D, Kluzniak W, Park J, Sellers T, Lin HY, Isaacs WB, Partin AW, Brenner H, Dieffenbach AK, Stegmaier C, Chen C, Giovannucci EL, Ma J, Stampfer M, Penney KL, Mucci L, John EM, Ingles SA, Kittles RA, Murphy AB, Pandha H, Michael A, Kierzek AM, Blot W, Signorello LB, Zheng W, Albanes D, Virtamo J, Weinstein S, Nemesure B, Carpten J, Leske C, Wu SY, Hennis A, Kibel AS, Rybicki BA, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Zheng SL, Batra J, Clements J, Spurdle A, Teixeira MR, Paulo P, Maia S, Slavov C, Kaneva R, Mitev V, Witte JS, Casey G, Gillanders EM, Seminara D, Riboli E, Hamdy FC, Coetzee GA, Li Q, Freedman ML, Hunter DJ, Muir K, Gronberg H, Neal DE, Southey M, Giles GG, Severi G, Cook MB, Nakagawa H, Wiklund F, Kraft P, Chanock SJ, Henderson BE, Easton DF, Eeles RA, Haiman CA. A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer. Nat Genet. 2014 Oct; 46(10):1103-9. PMID: 25217961; PMCID: PMC4383163.
    41. Han Y, Signorello LB, Strom SS, Kittles RA, Rybicki BA, Stanford JL, Goodman PJ, Berndt SI, Carpten J, Casey G, Chu L, Conti DV, Rand KA, Diver WR, Hennis AJ, John EM, Kibel AS, Klein EA, Kolb S, Le Marchand L, Leske MC, Murphy AB, Neslund-Dudas C, Park JY, Pettaway C, Rebbeck TR, Gapstur SM, Zheng SL, Wu SY, Witte JS, Xu J, Isaacs W, Ingles SA, Hsing A, Easton DF, Eeles RA, Schumacher FR, Chanock S, Nemesure B, Blot WJ, Stram DO, Henderson BE, Haiman CA. Generalizability of established prostate cancer risk variants in men of African ancestry. Int J Cancer. 2015 Mar 01; 136(5):1210-7. PMID: 25044450; PMCID: PMC4268262.
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    82. Choi JH, Yee SW, Ramirez AH, Morrissey KM, Jang GH, Joski PJ, Mefford JA, Hesselson SE, Schlessinger A, Jenkins G, Castro RA, Johns SJ, Stryke D, Sali A, Ferrin TE, Witte JS, Kwok PY, Roden DM, Wilke RA, McCarty CA, Davis RL, Giacomini KM. A common 5'-UTR variant in MATE2-K is associated with poor response to metformin. Clin Pharmacol Ther. 2011 Nov; 90(5):674-84. PMID: 21956618; PMCID: PMC3329222.
    83. DuBois SG, Goldsby R, Segal M, Woo J, Copren K, Kane JP, Pullinger CR, Matthay KK, Witte J, Lessnick SL, Robison LL, Bhatia S, Strong LC. Evaluation of polymorphisms in EWSR1 and risk of Ewing sarcoma: a report from the Childhood Cancer Survivor Study. Pediatr Blood Cancer. 2012 Jul 15; 59(1):52-6. PMID: 21793187; PMCID: PMC3204324.
    84. Hardin J, Cheng I, Witte JS. Impact of consumption of vegetable, fruit, grain, and high glycemic index foods on aggressive prostate cancer risk. Nutr Cancer. 2011; 63(6):860-72. PMID: 21774611; PMCID: PMC3209415.
    85. Hinch AG, Tandon A, Patterson N, Song Y, Rohland N, Palmer CD, Chen GK, Wang K, Buxbaum SG, Akylbekova EL, Aldrich MC, Ambrosone CB, Amos C, Bandera EV, Berndt SI, Bernstein L, Blot WJ, Bock CH, Boerwinkle E, Cai Q, Caporaso N, Casey G, Cupples LA, Deming SL, Diver WR, Divers J, Fornage M, Gillanders EM, Glessner J, Harris CC, Hu JJ, Ingles SA, Isaacs W, John EM, Kao WH, Keating B, Kittles RA, Kolonel LN, Larkin E, Le Marchand L, McNeill LH, Millikan RC, Murphy A, Musani S, Neslund-Dudas C, Nyante S, Papanicolaou GJ, Press MF, Psaty BM, Reiner AP, Rich SS, Rodriguez-Gil JL, Rotter JI, Rybicki BA, Schwartz AG, Signorello LB, Spitz M, Strom SS, Thun MJ, Tucker MA, Wang Z, Wiencke JK, Witte JS, Wrensch M, Wu X, Yamamura Y, Zanetti KA, Zheng W, Ziegler RG, Zhu X, Redline S, Hirschhorn JN, Henderson BE, Taylor HA, Price AL, Hakonarson H, Chanock SJ, Haiman CA, Wilson JG, Reich D, Myers SR. The landscape of recombination in African Americans. Nature. 2011 Jul 20; 476(7359):170-5. PMID: 21775986; PMCID: PMC3154982.
    86. Witte JS. Of models and methods. Cancer Epidemiol Biomarkers Prev. 2011 Jun; 20(6):1059-60. PMID: 21652535.
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    87. Haiman CA, Chen GK, Blot WJ, Strom SS, Berndt SI, Kittles RA, Rybicki BA, Isaacs WB, Ingles SA, Stanford JL, Diver WR, Witte JS, Chanock SJ, Kolb S, Signorello LB, Yamamura Y, Neslund-Dudas C, Thun MJ, Murphy A, Casey G, Sheng X, Wan P, Pooler LC, Monroe KR, Waters KM, Le Marchand L, Kolonel LN, Stram DO, Henderson BE. Characterizing genetic risk at known prostate cancer susceptibility loci in African Americans. PLoS Genet. 2011 May; 7(5):e1001387. PMID: 21637779; PMCID: PMC3102736.
    88. Haiman CA, Chen GK, Blot WJ, Strom SS, Berndt SI, Kittles RA, Rybicki BA, Isaacs WB, Ingles SA, Stanford JL, Diver WR, Witte JS, Hsing AW, Nemesure B, Rebbeck TR, Cooney KA, Xu J, Kibel AS, Hu JJ, John EM, Gueye SM, Watya S, Signorello LB, Hayes RB, Wang Z, Yeboah E, Tettey Y, Cai Q, Kolb S, Ostrander EA, Zeigler-Johnson C, Yamamura Y, Neslund-Dudas C, Haslag-Minoff J, Wu W, Thomas V, Allen GO, Murphy A, Chang BL, Zheng SL, Leske MC, Wu SY, Ray AM, Hennis AJ, Thun MJ, Carpten J, Casey G, Carter EN, Duarte ER, Xia LY, Sheng X, Wan P, Pooler LC, Cheng I, Monroe KR, Schumacher F, Le Marchand L, Kolonel LN, Chanock SJ, Van Den Berg D, Stram DO, Henderson BE. Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21. Nat Genet. 2011 Jun; 43(6):570-3. PMID: 21602798; PMCID: PMC3102788.
    89. Catalona WJ, Bailey-Wilson JE, Camp NJ, Chanock SJ, Cooney KA, Easton DF, Eeles RA, FitzGerald LM, Freedman ML, Gudmundsson J, Kittles RA, Margulies EH, McGuire BB, Ostrander EA, Rebbeck TR, Stanford JL, Thibodeau SN, Witte JS, Isaacs WB. National Cancer Institute Prostate Cancer Genetics Workshop. Cancer Res. 2011 May 15; 71(10):3442-6. PMID: 21558387; PMCID: PMC3096727.
    90. Witte JS, Hoffmann TJ. Polygenic modeling of genome-wide association studies: an application to prostate and breast cancer. OMICS. 2011 Jun; 15(6):393-8. PMID: 21348634; PMCID: PMC3125548.
    91. Kompass KS, Witte JS. Co-regulatory expression quantitative trait loci mapping: method and application to endometrial cancer. BMC Med Genomics. 2011 Jan 12; 4:6. PMID: 21226949; PMCID: PMC3032645.
    92. Witte JS. Personalized prostate cancer screening: improving PSA tests with genomic information. Sci Transl Med. 2010 Dec 15; 2(62):62ps55. PMID: 21160075.
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    93. Chang BL, Spangler E, Gallagher S, Haiman CA, Henderson B, Isaacs W, Benford ML, Kidd LR, Cooney K, Strom S, Ingles SA, Stern MC, Corral R, Joshi AD, Xu J, Giri VN, Rybicki B, Neslund-Dudas C, Kibel AS, Thompson IM, Leach RJ, Ostrander EA, Stanford JL, Witte J, Casey G, Eeles R, Hsing AW, Chanock S, Hu JJ, John EM, Park J, Stefflova K, Zeigler-Johnson C, Rebbeck TR. Validation of genome-wide prostate cancer associations in men of African descent. Cancer Epidemiol Biomarkers Prev. 2011 Jan; 20(1):23-32. PMID: 21071540; PMCID: PMC3110616.
    94. Hoffmann TJ, Marini NJ, Witte JS. Comprehensive approach to analyzing rare genetic variants. PLoS One. 2010 Nov 03; 5(11):e13584. PMID: 21072163; PMCID: PMC2972202.
    95. Liu X, Cheng I, Plummer SJ, Suarez BK, Casey G, Catalona WJ, Witte JS. Fine-mapping of prostate cancer aggressiveness loci on chromosome 7q22-35. Prostate. 2011 May 15; 71(7):682-9. PMID: 20945404; PMCID: PMC3027848.
    96. Reese AC, Hardin J, Cheng I, Casey G, Witte JS. Non-Steroidal Anti-Inflammatory Drugs, Variation in Inflammatory Genes, and Aggressive Prostate Cancer. Pharmaceuticals (Basel). 2010 Oct 08; 3(10):3127-3142. PMID: 24023525.
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    97. Tai YC, Kvale MN, Witte JS. Segmentation and estimation for SNP microarrays: a Bayesian multiple change-point approach. Biometrics. 2010 Sep; 66(3):675-83. PMID: 19764955; PMCID: PMC3766751.
    98. Cheng I, Plummer SJ, Neslund-Dudas C, Klein EA, Casey G, Rybicki BA, Witte JS. Prostate cancer susceptibility variants confer increased risk of disease progression. Cancer Epidemiol Biomarkers Prev. 2010 Sep; 19(9):2124-32. PMID: 20651075; PMCID: PMC2950095.
    99. Atkinson EJ, McDonnell SK, Witte JS, Crawford DC, Fan Y, Fridley B, Li D, Li L, Rodin A, Sadee W, Speed T, Weiss ST, Yang J, Yerges L, Schaid DJ. Conference Scene: Lessons learned from the 5th Statistical Analysis Workshop of the Pharmacogenetics Research Network. Pharmacogenomics. 2010 Mar; 11(3):297-303. PMID: 20235785.
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    100. Cheng I, Witte JS, Jacobsen SJ, Haque R, Quinn VP, Quesenberry CP, Caan BJ, Van Den Eeden SK. Prostatitis, sexually transmitted diseases, and prostate cancer: the California Men's Health Study. PLoS One. 2010 Jan 15; 5(1):e8736. PMID: 20090948; PMCID: PMC2806913.
    101. Witte JS. Genome-wide association studies and beyond. Annu Rev Public Health. 2010; 31:9-20 4 p following 20. PMID: 20235850; PMCID: PMC3997166.
    102. Jorgenson E, Kvale M, Witte JS. VALID: visualization of association study results and linkage disequilibrium. Genet Epidemiol. 2009 Nov; 33(7):599-603. PMID: 19197947; PMCID: PMC3258024.
    103. Reese AC, Fradet V, Witte JS. Omega-3 fatty acids, genetic variants in COX-2 and prostate cancer. J Nutrigenet Nutrigenomics. 2009; 2(3):149-58. PMID: 19776642; PMCID: PMC2820568.
    104. Khoury MJ, McBride CM, Schully SD, Ioannidis JP, Feero WG, Janssens AC, Gwinn M, Simons-Morton DG, Bernhardt JM, Cargill M, Chanock SJ, Church GM, Coates RJ, Collins FS, Croyle RT, Davis BR, Downing GJ, Duross A, Friedman S, Gail MH, Ginsburg GS, Green RC, Greene MH, Greenland P, Gulcher JR, Hsu A, Hudson KL, Kardia SL, Kimmel PL, Lauer MS, Miller AM, Offit K, Ransohoff DF, Roberts JS, Rasooly RS, Stefansson K, Terry SF, Teutsch SM, Trepanier A, Wanke KL, Witte JS, Xu J. The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop. Genet Med. 2009 Aug; 11(8):559-67. PMID: 19617843; PMCID: PMC2936269.
    105. Cheng I, Witte JS, McClure LA, Shema SJ, Cockburn MG, John EM, Clarke CA. Socioeconomic status and prostate cancer incidence and mortality rates among the diverse population of California. Cancer Causes Control. 2009 Oct; 20(8):1431-40. PMID: 19526319.
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    106. Fradet V, Cheng I, Casey G, Witte JS. Dietary omega-3 fatty acids, cyclooxygenase-2 genetic variation, and aggressive prostate cancer risk. Clin Cancer Res. 2009 Apr 01; 15(7):2559-66. PMID: 19318492; PMCID: PMC2749066.
    107. Ross PL, Cheng I, Liu X, Cicek MS, Carroll PR, Casey G, Witte JS. Carboxypeptidase 4 gene variants and early-onset intermediate-to-high risk prostate cancer. BMC Cancer. 2009 Feb 26; 9:69. PMID: 19245716; PMCID: PMC2657151.
    108. Carmichael SL, Witte JS, Shaw GM. Nutrient pathways and neural tube defects: a semi-Bayesian hierarchical analysis. Epidemiology. 2009 Jan; 20(1):67-73. PMID: 19234400.
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    109. Witte JS. Prostate cancer genomics: towards a new understanding. Nat Rev Genet. 2009 Feb; 10(2):77-82. PMID: 19104501; PMCID: PMC2721916.
    110. Arora M, Nagaraj S, Witte J, DeFor TE, MacMillan M, Burns LJ, Weisdorf DJ. New classification of chronic GVHD: added clarity from the consensus diagnoses. Bone Marrow Transplant. 2009 Jan; 43(2):149-53. PMID: 18794869.
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    111. Cheng I, Witte JS. The role of genetic variation in Toll-like receptor 4 in prostate cancer susceptibility: a review. Expert Opin Med Diagn. 2008 Feb; 2(2):143-9. PMID: 23485134.
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    112. Cheng I, Plummer SJ, Jorgenson E, Liu X, Rybicki BA, Casey G, Witte JS. 8q24 and prostate cancer: association with advanced disease and meta-analysis. Eur J Hum Genet. 2008 Apr; 16(4):496-505. PMID: 18231127; PMCID: PMC2819154.
    113. Cordell HJ, de Andrade M, Babron MC, Bartlett CW, Beyene J, Bickeböller H, Culverhouse R, Cupples LA, Daw EW, Dupuis J, Falk CT, Ghosh S, Goddard KA, Goode EL, Hauser ER, Martin LJ, Martinez M, North KE, Saccone NL, Schmidt S, Tapper W, Thomas D, Tritchler D, Vieland VJ, Wijsman EM, Wilcox MA, Witte JS, Yang Q, Ziegler A, Almasy L, Maccluer JW. Genetic Analysis Workshop 15: gene expression analysis and approaches to detecting multiple functional loci. BMC Proc. 2007; 1 Suppl 1:S1. PMID: 18466438; PMCID: PMC2367529.
    114. Chen GK, Jorgenson E, Witte JS. An empirical evaluation of the common disease-common variant hypothesis. BMC Proc. 2007; 1 Suppl 1:S5. PMID: 18466549; PMCID: PMC2367531.
    115. Jorgenson E, Witte JS. Genome-wide association studies of cancer. Future Oncol. 2007 Aug; 3(4):419-27. PMID: 17661717.
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    116. Cheng I, Liu X, Plummer SJ, Krumroy LM, Casey G, Witte JS. COX2 genetic variation, NSAIDs, and advanced prostate cancer risk. Br J Cancer. 2007 Aug 20; 97(4):557-61. PMID: 17609663; PMCID: PMC2360347.
    117. Chen GK, Witte JS. Enriching the analysis of genomewide association studies with hierarchical modeling. Am J Hum Genet. 2007 Aug; 81(2):397-404. PMID: 17668389; PMCID: PMC1950795.
    118. Cheng I, Krumroy LM, Plummer SJ, Casey G, Witte JS. MIC1 and IL1RN genetic variation and advanced prostate cancer risk. Cancer Epidemiol Biomarkers Prev. 2007 Jun; 16(6):1309-11. PMID: 17548705.
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    119. Witte JS. Multiple prostate cancer risk variants on 8q24. Nat Genet. 2007 May; 39(5):579-80. PMID: 17460686.
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    120. Thomas DC, Witte JS, Greenland S. Dissecting effects of complex mixtures: who's afraid of informative priors? Epidemiology. 2007 Mar; 18(2):186-90. PMID: 17301703.
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    121. Liu X, Cicek MS, Plummer SJ, Jorgenson E, Casey G, Witte JS. Association of testis derived transcript gene variants and prostate cancer risk. J Urol. 2007 Mar; 177(3):894-8. PMID: 17296370.
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    122. Jorgenson E, Deitcher SR, Cicek M, Liu X, Plummer S, Casey G, Witte JS. Plasminogen activator inhibitor type-1 (PAI-1) polymorphism 4G/5G is associated with prostate cancer among men with a positive family history. Prostate. 2007 Feb 01; 67(2):172-7. PMID: 17044080.
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    123. Cheng I, Plummer SJ, Casey G, Witte JS. Toll-like receptor 4 genetic variation and advanced prostate cancer risk. Cancer Epidemiol Biomarkers Prev. 2007 Feb; 16(2):352-5. PMID: 17301271.
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    124. Liu X, Schumacher FR, Plummer SJ, Jorgenson E, Casey G, Witte JS. Trans-fatty acid intake and increased risk of advanced prostate cancer: modification by RNASEL R462Q variant. Carcinogenesis. 2007 Jun; 28(6):1232-6. PMID: 17234723.
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    125. Witte JS, Schnell AH, Cordell HJ, Spielman RS, Amos CI, Miller MB, Almasy L, MacCluer JW. Introduction to Genetic Analysis Workshop 15 summaries. Genet Epidemiol. 2007; 31 Suppl 1:S1-6. PMID: 18046756.
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    126. Chen GK, Zheng T, Witte JS, Goode EL, Gao L, Hu P, Suh YJ, Suktitipat B, Szymczak S, Woo JH, Zhang W. Genome-wide association analyses of expression phenotypes. Genet Epidemiol. 2007; 31 Suppl 1:S7-S11. PMID: 18046762.
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    127. Cicek MS, Liu X, Schumacher FR, Casey G, Witte JS. Vitamin D receptor genotypes/haplotypes and prostate cancer risk. Cancer Epidemiol Biomarkers Prev. 2006 Dec; 15(12):2549-52. PMID: 17164384.
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    128. Jorgenson E, Witte JS. A gene-centric approach to genome-wide association studies. Nat Rev Genet. 2006 Nov; 7(11):885-91. PMID: 17047687.
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    129. Liu X, Plummer SJ, Nock NL, Casey G, Witte JS. Nonsteroidal antiinflammatory drugs and decreased risk of advanced prostate cancer: modification by lymphotoxin alpha. Am J Epidemiol. 2006 Nov 15; 164(10):984-9. PMID: 16931544.
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    130. Tung JY, Rosen MP, Nelson LM, Turek PJ, Witte JS, Cramer DW, Cedars MI, Reijo-Pera RA. Novel missense mutations of the Deleted-in-AZoospermia-Like (DAZL) gene in infertile women and men. Reprod Biol Endocrinol. 2006 Aug 02; 4:40. PMID: 16884537; PMCID: PMC1557510.
    131. Sapru A, Wiemels JL, Witte JS, Ware LB, Matthay MA. Acute lung injury and the coagulation pathway: Potential role of gene polymorphisms in the protein C and fibrinolytic pathways. Intensive Care Med. 2006 Sep; 32(9):1293-303. PMID: 16770611.
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    132. Nock NL, Liu X, Cicek MS, Li L, Macarie F, Rybicki BA, Plummer SJ, Maclennan GT, Casey G, Witte JS. Polymorphisms in polycyclic aromatic hydrocarbon metabolism and conjugation genes, interactions with smoking and prostate cancer risk. Cancer Epidemiol Biomarkers Prev. 2006 Apr; 15(4):756-61. PMID: 16614120.
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    133. Nock NL, Cicek MS, Li L, Liu X, Rybicki BA, Moreira A, Plummer SJ, Casey G, Witte JS. Polymorphisms in estrogen bioactivation, detoxification and oxidative DNA base excision repair genes and prostate cancer risk. Carcinogenesis. 2006 Sep; 27(9):1842-8. PMID: 16569655.
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    134. Jorgenson E, Witte JS. Coverage and power in genomewide association studies. Am J Hum Genet. 2006 May; 78(5):884-8. PMID: 16642443; PMCID: PMC1474045.
    135. Casey G, Neville PJ, Liu X, Plummer SJ, Cicek MS, Krumroy LM, Curran AP, McGreevy MR, Catalona WJ, Klein EA, Witte JS. Podocalyxin variants and risk of prostate cancer and tumor aggressiveness. Hum Mol Genet. 2006 Mar 01; 15(5):735-41. PMID: 16434482.
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    136. Liu X, Jorgenson E, Witte JS. Hierarchical modeling in association studies of multiple phenotypes. BMC Genet. 2005 Dec 30; 6 Suppl 1:S104. PMID: 16451560; PMCID: PMC1866835.
    137. Liu X, Rybicki BA, Casey G, Witte JS. Relationship between body size and prostate cancer in a sibling based case-control study. J Urol. 2005 Dec; 174(6):2169-73. PMID: 16280757.
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    138. Tung JY, Rosen MP, Nelson LM, Turek PJ, Witte JS, Cramer DW, Cedars MI, Pera RA. Variants in Deleted in AZoospermia-Like (DAZL) are correlated with reproductive parameters in men and women. Hum Genet. 2006 Feb; 118(6):730-40. PMID: 16328470.
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    139. Li L, Cicek MS, Casey G, Witte JS. No association between genetic polymorphisms in insulin and insulin receptor substrate-1 and prostate cancer. Cancer Epidemiol Biomarkers Prev. 2005 Oct; 14(10):2462-3. PMID: 16214935.
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    140. Strassmaier T, Uma R, Ghatpande AS, Bandyopadhyay T, Schaffer M, Witte J, McDougal PG, Brown RL, Karpen JW. Modifications to the tetracaine scaffold produce cyclic nucleotide-gated channel blockers with widely varying efficacies. J Med Chem. 2005 Sep 08; 48(18):5805-12. PMID: 16134947; PMCID: PMC2467444.
    141. Cicek MS, Liu X, Casey G, Witte JS. Role of androgen metabolism genes CYP1B1, PSA/KLK3, and CYP11alpha in prostate cancer risk and aggressiveness. Cancer Epidemiol Biomarkers Prev. 2005 Sep; 14(9):2173-7. PMID: 16172228.
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    142. Pinto D, de Haan GJ, Carton D, Bader A, Witte J, Peters E, van Erp MG, Vandereyken W, Boezeman EH, Boon P, Halley DJ, Koeleman BP, Lindhout D. Gene symbol: KCNQ2. Disease: Benign neonatal familial convulsion. Hum Genet. 2005 Jul; 117(2-3):300. PMID: 16156031.
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    143. Jorgenson E, Liu X, Witte JS. Case-control analyses: Geneopardy! Genet Epidemiol. 2005; 29 Suppl 1:S86-90. PMID: 16342187.
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    144. Li L, Cicek MS, Casey G, Witte JS. No association between a tetranucleotide repeat polymorphism of CYP19 and prostate cancer. Cancer Epidemiol Biomarkers Prev. 2004 Dec; 13(12):2280-1. PMID: 15598794.
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    145. Thompson D, Witte JS, Slattery M, Goldgar D. Increased power for case-control studies of single nucleotide polymorphisms through incorporation of family history and genetic constraints. Genet Epidemiol. 2004 Nov; 27(3):215-24. PMID: 15389928.
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    146. Cicek MS, Nock NL, Li L, Conti DV, Casey G, Witte JS. Relationship between methylenetetrahydrofolate reductase C677T and A1298C genotypes and haplotypes and prostate cancer risk and aggressiveness. Cancer Epidemiol Biomarkers Prev. 2004 Aug; 13(8):1331-6. PMID: 15298954.
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    147. Hung RJ, Brennan P, Malaveille C, Porru S, Donato F, Boffetta P, Witte JS. Using hierarchical modeling in genetic association studies with multiple markers: application to a case-control study of bladder cancer. Cancer Epidemiol Biomarkers Prev. 2004 Jun; 13(6):1013-21. PMID: 15184258.
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    148. Loukola A, Chadha M, Penn SG, Rank D, Conti DV, Thompson D, Cicek M, Love B, Bivolarevic V, Yang Q, Jiang Y, Hanzel DK, Dains K, Paris PL, Casey G, Witte JS. Comprehensive evaluation of the association between prostate cancer and genotypes/haplotypes in CYP17A1, CYP3A4, and SRD5A2. Eur J Hum Genet. 2004 Apr; 12(4):321-32. PMID: 14560315.
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    149. Cicek MS, Conti DV, Curran A, Neville PJ, Paris PL, Casey G, Witte JS. Association of prostate cancer risk and aggressiveness to androgen pathway genes: SRD5A2, CYP17, and the AR. Prostate. 2004 Apr 01; 59(1):69-76. PMID: 14991867.
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    150. Singer JB, Hill AE, Burrage LC, Olszens KR, Song J, Justice M, O'Brien WE, Conti DV, Witte JS, Lander ES, Nadeau JH. Genetic dissection of complex traits with chromosome substitution strains of mice. Science. 2004 Apr 16; 304(5669):445-8. PMID: 15031436.
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    151. Li L, Cicek MS, Casey G, Witte JS. No association between genetic polymorphisms in IGF-I and IGFBP-3 and prostate cancer. Cancer Epidemiol Biomarkers Prev. 2004 Mar; 13(3):497-8. PMID: 15006930.
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    152. Rybicki BA, Conti DV, Moreira A, Cicek M, Casey G, Witte JS. DNA repair gene XRCC1 and XPD polymorphisms and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev. 2004 Jan; 13(1):23-9. PMID: 14744728.
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    153. Xing C, Schumacher FR, Conti DV, Witte JS. Comparison of missing data approaches in linkage analysis. BMC Genet. 2003 Dec 31; 4 Suppl 1:S44. PMID: 14975112; PMCID: PMC1866480.
    154. Witte JS, Suarez BK, Thiel B, Lin J, Yu A, Banerjee TK, Burmester JK, Casey G, Catalona WJ. Genome-wide scan of brothers: replication and fine mapping of prostate cancer susceptibility and aggressiveness loci. Prostate. 2003 Dec 01; 57(4):298-308. PMID: 14601026.
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    155. Li L, Yu H, Schumacher F, Casey G, Witte JS. Relation of serum insulin-like growth factor-I (IGF-I) and IGF binding protein-3 to risk of prostate cancer (United States). Cancer Causes Control. 2003 Oct; 14(8):721-6. PMID: 14674736.
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    156. Plummer SJ, Conti DV, Paris PL, Curran AP, Casey G, Witte JS. CYP3A4 and CYP3A5 genotypes, haplotypes, and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev. 2003 Sep; 12(9):928-32. PMID: 14504207.
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    157. Neville PJ, Conti DV, Krumroy LM, Catalona WJ, Suarez BK, Witte JS, Casey G. Prostate cancer aggressiveness locus on chromosome segment 19q12-q13.1 identified by linkage and allelic imbalance studies. Genes Chromosomes Cancer. 2003 Apr; 36(4):332-9. PMID: 12619157.
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    158. Conti DV, Witte JS. Hierarchical modeling of linkage disequilibrium: genetic structure and spatial relations. Am J Hum Genet. 2003 Feb; 72(2):351-63. PMID: 12525994; PMCID: PMC379228.
    159. Thompson D, Stram D, Goldgar D, Witte JS. Haplotype tagging single nucleotide polymorphisms and association studies. Hum Hered. 2003; 56(1-3):48-55. PMID: 14614238.
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    160. Casey G, Neville PJ, Plummer SJ, Xiang Y, Krumroy LM, Klein EA, Catalona WJ, Nupponen N, Carpten JD, Trent JM, Silverman RH, Witte JS. RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases. Nat Genet. 2002 Dec; 32(4):581-3. PMID: 12415269.
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    161. Neville PJ, Conti DV, Paris PL, Levin H, Catalona WJ, Suarez BK, Witte JS, Casey G. Prostate cancer aggressiveness locus on chromosome 7q32-q33 identified by linkage and allelic imbalance studies. Neoplasia. 2002 Sep-Oct; 4(5):424-31. PMID: 12192601; PMCID: PMC1564121.
    162. Fijal BA, Idury RM, Witte JS. Analysis of mutational spectra: locating hotspots and clusters of mutations using recursive segmentation. Stat Med. 2002 Jul 15; 21(13):1867-85. PMID: 12111894.
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    163. Thomas DC, Witte JS. Point: population stratification: a problem for case-control studies of candidate-gene associations? Cancer Epidemiol Biomarkers Prev. 2002 Jun; 11(6):505-12. PMID: 12050090.
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    164. Nelson KA, Witte JS. Androgen receptor CAG repeats and prostate cancer. Am J Epidemiol. 2002 May 15; 155(10):883-90. PMID: 11994226.
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    165. Palmer LJ, Schnell AH, Witte JS, Elston RC. Parametric linkage analysis. Methods Mol Biol. 2002; 195:13-35. PMID: 12070879.
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    166. Witte JS, Palmer LJ, O'Connor RD, Hopkins PJ, Hall JM. Relation between tumour necrosis factor polymorphism TNFalpha-308 and risk of asthma. Eur J Hum Genet. 2002 Jan; 10(1):82-5. PMID: 11896460.
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    167. Knöpfle E, Mayer H, Wamser G, Bohndorf K, Witte J. [Ileus in colorectal carcinoma. Preoperative implantation of self-expanding metal stents and early elective surgery as an alternative to emergency surgery]. Chirurg. 2001 Oct; 72(10):1137-43. PMID: 11715616.
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    168. Goddard KA, Witte JS, Suarez BK, Catalona WJ, Olson JM. Model-free linkage analysis with covariates confirms linkage of prostate cancer to chromosomes 1 and 4. Am J Hum Genet. 2001 May; 68(5):1197-206. PMID: 11309685; PMCID: PMC1226100.
    169. Dotzenrath C, Goretzki PE, Cupisti K, Simon D, Witte J, Yang Q, Ohmann C, Röher HD. Is there any consensus in diagnostic and operative strategy with respect to medullary thyroid cancer? A questionnaire answered by 73 endocrine surgical units. Langenbecks Arch Surg. 2001 Feb; 386(1):47-52. PMID: 11405089.
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    170. Kim LL, Fijal BA, Witte JS. Hierarchical modeling of the relation between sequence variants and a quantitative trait: addressing multiple comparison and population stratification issues. Genet Epidemiol. 2001; 21 Suppl 1:S668-73. PMID: 11793759.
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    171. Mosley J, Conti DV, Elston RC, Witte JS. Impact of preadjusting a quantitative phenotype prior to sib-pair linkage analysis when gene x environment interaction exists. Genet Epidemiol. 2001; 21 Suppl 1:S837-42. PMID: 11793789.
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    172. Fijal BA, Kim LL, Buxbaum SG, Witte JS. Predicting quantitative trait levels by modeling SNP interaction. Genet Epidemiol. 2001; 21 Suppl 1:S608-13. PMID: 11793747.
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    173. Witte JS, Fijal BA. Introduction: analysis of sequence data and population structure. Genet Epidemiol. 2001; 21 Suppl 1:S600-1. PMID: 11793745.
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    174. Cupisti K, Simon D, Wolf A, Gerharz CD, Goretzki PE, Dotzenrath C, Witte J, Röher HD. Surgical treatment of postoperative, incidentally diagnosed small sporadic C-cell carcinomas of the thyroid. Langenbecks Arch Surg. 2000 Dec; 385(8):526-30. PMID: 11201009.
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    175. Witte J, Shivananda S, Lennard-Jones JE, Beltrami M, Politi P, Bonanomi A, Tsianos EV, Mouzas I, Schulz TB, Monteiro E, Clofent J, Odes S, Limonard CB, Stockbrügger RW, Russel MG. Disease outcome in inflammatory bowel disease: mortality, morbidity and therapeutic management of a 796-person inception cohort in the European Collaborative Study on Inflammatory Bowel Disease (EC-IBD). Scand J Gastroenterol. 2000 Dec; 35(12):1272-7. PMID: 11199366.
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    176. Witte J, Goretzki PE, Dotzenrath C, Simon D, Felis P, Neubauer M, Röher HD. Surgery for Graves' disease: total versus subtotal thyroidectomy-results of a prospective randomized trial. World J Surg. 2000 Nov; 24(11):1303-11. PMID: 11038198.
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    177. Witte JS, Greenland S, Kim LL, Arab L. Multilevel modeling in epidemiology with GLIMMIX. Epidemiology. 2000 Nov; 11(6):684-8. PMID: 11055630.
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    178. Suarez BK, Lin J, Witte JS, Conti DV, Resnick MI, Klein EA, Burmester JK, Vaske DA, Banerjee TK, Catalona WJ. Replication linkage study for prostate cancer susceptibility genes. Prostate. 2000 Oct 01; 45(2):106-14. PMID: 11027409.
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    179. Cardon LR, Idury RM, Harris TJ, Witte JS, Elston RC. Testing drug response in the presence of genetic information: sampling issues for clinical trials. Pharmacogenetics. 2000 Aug; 10(6):503-10. PMID: 10975604.
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    180. Wandel C, Witte JS, Hall JM, Stein CM, Wood AJ, Wilkinson GR. CYP3A activity in African American and European American men: population differences and functional effect of the CYP3A4*1B5'-promoter region polymorphism. Clin Pharmacol Ther. 2000 Jul; 68(1):82-91. PMID: 10945319.
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    181. Paris PL, Witte JS, Kupelian PA, Levin H, Klein EA, Catalona WJ, Casey G. Identification and fine mapping of a region showing a high frequency of allelic imbalance on chromosome 16q23.2 that corresponds to a prostate cancer susceptibility locus. Cancer Res. 2000 Jul 01; 60(13):3645-9. PMID: 10910080.
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    182. Witte JS, Goddard KA, Conti DV, Elston RC, Lin J, Suarez BK, Broman KW, Burmester JK, Weber JL, Catalona WJ. Genomewide scan for prostate cancer-aggressiveness loci. Am J Hum Genet. 2000 Jul; 67(1):92-9. PMID: 10825281; PMCID: PMC1287106.
    183. Suarez BK, Lin J, Burmester JK, Broman KW, Weber JL, Banerjee TK, Goddard KA, Witte JS, Elston RC, Catalona WJ. A genome screen of multiplex sibships with prostate cancer. Am J Hum Genet. 2000 Mar; 66(3):933-44. PMID: 10712208; PMCID: PMC1288174.
    184. Witte JS, Elston RC, Cardon LR. On the relative sample size required for multiple comparisons. Stat Med. 2000 Feb 15; 19(3):369-72. PMID: 10649302.
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    185. Fijal BA, Hall JM, Witte JS. Clinical trials in the genomic era: effects of protective genotypes on sample size and duration of trial. Control Clin Trials. 2000 Feb; 21(1):7-20. PMID: 10660000.
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    186. Fietze I, Röttig J, Quispe-Bravo S, Riedel F, Witte J, Baumann G, Witt C. Sleep apnea syndrome in patients with cardiac pacemaker. Respiration. 2000; 67(3):268-71. PMID: 10867594.
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    187. Goddard KA, Hopkins PJ, Hall JM, Witte JS. Linkage disequilibrium and allele-frequency distributions for 114 single-nucleotide polymorphisms in five populations. Am J Hum Genet. 2000 Jan; 66(1):216-34. PMID: 10631153; PMCID: PMC1288328.
    188. Witte J, Reibis R, Bondke HJ, Baumann G. [Biatrial pacing as an effective therapy method of paroxysmal atrial fibrillation]. Wien Med Wochenschr. 2000; 150(19-21):419-23. PMID: 11132436.
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    189. Olson JM, Witte JS, Elston RC. Genetic mapping of complex traits. Stat Med. 1999 Nov 15; 18(21):2961-81. PMID: 10523753.
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    190. Paris PL, Kupelian PA, Hall JM, Williams TL, Levin H, Klein EA, Casey G, Witte JS. Association between a CYP3A4 genetic variant and clinical presentation in African-American prostate cancer patients. Cancer Epidemiol Biomarkers Prev. 1999 Oct; 8(10):901-5. PMID: 10548319.
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    191. Meyer C, Witte J, Hildmann A, Hennecke KH, Schunck KU, Maul K, Franke U, Fahnenstich H, Rabe H, Rossi R, Hartmann S, Gortner L. Neonatal screening for hearing disorders in infants at risk: incidence, risk factors, and follow-up. Pediatrics. 1999 Oct; 104(4 Pt 1):900-4. PMID: 10506232.
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    192. Haile RW, Witte JS, Gold M, Cressey R, McGee C, Millikan RC, Glasser A, Harawa N, Ervin C, Harmon P, Harper J, Dermand J, Alamillo J, Barrett K, Nides M, Wang G. The health effects of swimming in ocean water contaminated by storm drain runoff. Epidemiology. 1999 Jul; 10(4):355-63. PMID: 10401868.
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    193. Kupelian PA, Klein EA, Witte JS. Re: Biological aggressiveness of hereditary prostate cancer: long-term evaluation following radical prostatectomy. J Urol. 1999 May; 161(5):1585-6. PMID: 10210420.
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    194. Witte JS, Gauderman WJ, Thomas DC. Asymptotic bias and efficiency in case-control studies of candidate genes and gene-environment interactions: basic family designs. Am J Epidemiol. 1999 Apr 15; 149(8):693-705. PMID: 10206618.
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    195. Gauderman WJ, Witte JS, Thomas DC. Family-based association studies. J Natl Cancer Inst Monogr. 1999; (26):31-7. PMID: 10854483.
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    196. Jacobs KB, Wedig GC, Schnell AH, Witte JS, Elston RC. Model-based and model-free multipoint genome-wide linkage analysis of alcoholism. Genet Epidemiol. 1999; 17 Suppl 1:S175-80. PMID: 10597432.
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    197. Witte JS, Carlin JB, Hopper JL. Likelihood-based approach to estimating twin concordance for dichotomous traits. Genet Epidemiol. 1999; 16(3):290-304. PMID: 10096691.
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    198. Klein EA, Kupelian PA, Witte JS. Does a family history of prostate cancer result in more aggressive disease? Prostate Cancer Prostatic Dis. 1998 Dec; 1(6):297-300. PMID: 12496870.
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    199. Witte JS, Greenland S, Kim LL. Software for hierarchical modeling of epidemiologic data. Epidemiology. 1998 Sep; 9(5):563-6. PMID: 9730038.
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    200. Lin HJ, Probst-Hensch NM, Louie AD, Kau IH, Witte JS, Ingles SA, Frankl HD, Lee ER, Haile RW. Glutathione transferase null genotype, broccoli, and lower prevalence of colorectal adenomas. Cancer Epidemiol Biomarkers Prev. 1998 Aug; 7(8):647-52. PMID: 9718215.
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    201. Fijal BA, Witte JS. Evaluating the performance of a genetic test using information from previous studies in place of a gold standard. Med Care. 1998 Aug; 36(8 Suppl):AS46-56. PMID: 9708582.
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    202. Riethmüller G, Holz E, Schlimok G, Schmiegel W, Raab R, Höffken K, Gruber R, Funke I, Pichlmaier H, Hirche H, Buggisch P, Witte J, Pichlmayr R. Monoclonal antibody therapy for resected Dukes' C colorectal cancer: seven-year outcome of a multicenter randomized trial. J Clin Oncol. 1998 May; 16(5):1788-94. PMID: 9586892.
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    203. Kupelian PA, Klein EA, Witte JS, Kupelian VA, Suh JH. Familial prostate cancer: a different disease? J Urol. 1997 Dec; 158(6):2197-201. PMID: 9366343.
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    204. Haile RW, Witte JS, Longnecker MP, Probst-Hensch N, Chen MJ, Harper J, Frankl HD, Lee ER. A sigmoidoscopy-based case-control study of polyps: macronutrients, fiber and meat consumption. Int J Cancer. 1997 Nov 14; 73(4):497-502. PMID: 9389562.
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    205. Kupelian PA, Kupelian VA, Witte JS, Macklis R, Klein EA. Family history of prostate cancer in patients with localized prostate cancer: an independent predictor of treatment outcome. J Clin Oncol. 1997 Apr; 15(4):1478-80. PMID: 9193343.
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    206. Witte JS, Greenland S. A nested approach to evaluating dose-response and trend. Ann Epidemiol. 1997 Apr; 7(3):188-93. PMID: 9141641.
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    207. Shikany JM, Witte JS, Henning SM, Swendseid ME, Bird CL, Frankl HD, Lee ER, Haile RW. Plasma carotenoids and the prevalence of adenomatous polyps of the distal colon and rectum. Am J Epidemiol. 1997 Mar 15; 145(6):552-7. PMID: 9063346.
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    208. Probst-Hensch NM, Sinha R, Longnecker MP, Witte JS, Ingles SA, Frankl HD, Lee ER, Haile RW. Meat preparation and colorectal adenomas in a large sigmoidoscopy-based case-control study in California (United States). Cancer Causes Control. 1997 Mar; 8(2):175-83. PMID: 9134241.
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    209. Witte JS, Ursin G, Siemiatycki J, Thompson WD, Paganini-Hill A, Haile RW. Diet and premenopausal bilateral breast cancer: a case-control study. Breast Cancer Res Treat. 1997 Feb; 42(3):243-51. PMID: 9065608.
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    210. Witte JS. Genetic analysis with hierarchical models. Genet Epidemiol. 1997; 14(6):1137-42. PMID: 9433637.
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    211. Schnell AH, Karunaratne PM, Witte JS, Dawson DV, Elston RC. Modeling age of onset and residual familial correlations for the linkage analysis of bipolar disorder. Genet Epidemiol. 1997; 14(6):675-80. PMID: 9433562.
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    212. Witte J, Schlotmann U, Simon D, Dotzenrath C, Ohmann C, Goretzki PE. [Significance of lymph node metastases of differentiated thyroid gland carcinomas and C-cell carcinomas for prognosis--a meta-analysis]. Zentralbl Chir. 1997; 122(4):259-65. PMID: 9221636.
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    213. Witte JS, Longnecker MP, Bird CL, Lee ER, Frankl HD, Haile RW. Relation of vegetable, fruit, and grain consumption to colorectal adenomatous polyps. Am J Epidemiol. 1996 Dec 01; 144(11):1015-25. PMID: 8942431.
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    214. Simon D, Goretzki PE, Witte J, Röher HD. Incidence of regional recurrence guiding radicality in differentiated thyroid carcinoma. World J Surg. 1996 Sep; 20(7):860-6; discussion 866. PMID: 8678963.
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    215. Cauthen GM, Dooley SW, Onorato IM, Ihle WW, Burr JM, Bigler WJ, Witte J, Castro KG. Transmission of Mycobacterium tuberculosis from tuberculosis patients with HIV infection or AIDS. Am J Epidemiol. 1996 Jul 01; 144(1):69-77. PMID: 8659487.
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    216. Bird CL, Witte JS, Swendseid ME, Shikany JM, Hunt IF, Frankl HD, Lee ER, Longnecker MP, Haile RW. Plasma ferritin, iron intake, and the risk of colorectal polyps. Am J Epidemiol. 1996 Jul 01; 144(1):34-41. PMID: 8659483.
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    217. Witte JS, Haile RW. Agreement in alcohol consumption levels as measured by two different questionnaires. J Stud Alcohol. 1996 Jul; 57(4):406-9. PMID: 8776682.
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    218. Witte JS, Greenland S. Simulation study of hierarchical regression. Stat Med. 1996 Jun 15; 15(11):1161-70. PMID: 8804145.
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    219. Witte JS, Elston RC, Schork NJ. Genetic dissection of complex traits. Nat Genet. 1996 Apr; 12(4):355-6; author reply 357-8. PMID: 8630483.
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    220. Olson JM, Witte JS, Elston RC. Association within twin pairs for a dichotomous trait. Genet Epidemiol. 1996; 13(5):489-99. PMID: 8905395.
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    221. Haile RW, Witte JS, Ursin G, Siemiatycki J, Bertolli J, Douglas Thompson W, Paganini-Hill A. A case-control study of reproductive variables, alcohol, and smoking in premenopausal bilateral breast cancer. Breast Cancer Res Treat. 1996; 37(1):49-56. PMID: 8750527.
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    222. Bird CL, Swendseid ME, Witte JS, Shikany JM, Hunt IF, Frankl HD, Lee ER, Longnecker MP, Haile RW. Red cell and plasma folate, folate consumption, and the risk of colorectal adenomatous polyps. Cancer Epidemiol Biomarkers Prev. 1995 Oct-Nov; 4(7):709-14. PMID: 8672986.
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    223. Langholz B, Thomas DC, Witte J, Peters RK. Re: "A population-based case-cohort evaluation of the efficacy of mammographic screening for breast cancer". Am J Epidemiol. 1995 Aug 15; 142(4):448-50. PMID: 7625412.
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    224. Witte JS, Pike MC. Re: "Can energy adjustment separate the effects of energy from those of specific macronutrients?". Am J Epidemiol. 1995 Jul 15; 142(2):225-6. PMID: 7646721.
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    225. Witte JS, Thomas DC, Langholz B. Re: "Statistical significance testing in the American Journal of Epidemiology, 1970-1990". Am J Epidemiol. 1995 Jul 01; 142(1):101-3. PMID: 7785668.
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    226. Gauderman WJ, Witte JS, Faucett CL, Morrison J, Thomas DC. Genetic epidemiologic analysis of quantitative phenotypes using Gibbs sampling. Genet Epidemiol. 1995; 12(6):753-8. PMID: 8788004.
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    227. Witte JS, Greenland S, Haile RW, Bird CL. Hierarchical regression analysis applied to a study of multiple dietary exposures and breast cancer. Epidemiology. 1994 Nov; 5(6):612-21. PMID: 7841243.
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    228. Hehl AJ, Lindemann F, Witte J. [Simplified combination bypass or biliodigestive anastomosis alone in nonresectable carcinoma of the head of the pancreas?]. Chirurg. 1994 Jul; 65(7):624-9. PMID: 7523042.
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    229. Witzigmann H, Sagasser J, Meyer FM, Witte J. [Therapy of anal cancer]. Chirurg. 1994 Apr; 65(4):344-51. PMID: 8020355.
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    230. Goretzki PE, Simon D, Frilling A, Witte J, Reiners C, Grussendorf M, Horster FA, Röher HD. Surgical reintervention for differentiated thyroid cancer. Br J Surg. 1993 Aug; 80(8):1009-12. PMID: 8402050.
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    231. Ciesielski C, Marianos D, Ou CY, Dumbaugh R, Witte J, Berkelman R, Gooch B, Myers G, Luo CC, Schochetman G. Transmission of human immunodeficiency virus in a dental practice. Ann Intern Med. 1992 May 15; 116(10):798-805. PMID: 1567094.
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    232. Rosenblum L, Darrow W, Witte J, Cohen J, French J, Gill PS, Potterat J, Sikes K, Reich R, Hadler S. Sexual practices in the transmission of hepatitis B virus and prevalence of hepatitis delta virus infection in female prostitutes in the United States. JAMA. 1992 May 13; 267(18):2477-81. PMID: 1573724.
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    233. Khabbaz RF, Darrow WW, Hartley TM, Witte J, Cohen JB, French J, Gill PS, Potterat J, Sikes RK, Reich R. Seroprevalence and risk factors for HTLV-I/II infection among female prostitutes in the United States. JAMA. 1990 Jan 05; 263(1):60-4. PMID: 2293689.
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    234. Schneider BM, Schlimok G, Riethmüller G, Witte J. [Bone marrow micrometastases in colorectal cancers]. Fortschr Med. 1989 Jan 20; 107(2):59-63. PMID: 2707688.
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    235. Witte J, Möbes R, Zobel W, Wohlgemuth P. Results of pacemaker therapy in the German Democratic Republic. Organizational, methodological and technical aspects. Cor Vasa. 1989; 31(2):98-109. PMID: 2743781.
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    236. Witte J, Jochum M, Scherer R, Schramm W, Hochstrasser K, Fritz H. Disturbances of selected plasma proteins in hyperdynamic septic shock. Intensive Care Med. 1982; 8(5):215-22. PMID: 6182174.
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    237. Isselhard W, Geppert E, Menge M, Lauterjung KL, Vogel W, Witte J, Heugel E. Effect on myocardial metabolic pattern of local complete and incomplete ischemia. Recent Adv Stud Cardiac Struct Metab. 1975; 7:231-6. PMID: 1226439.
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    238. Witte J, Heublein B. [Familial cardiomyopathy. Case report]. Dtsch Gesundheitsw. 1971 Oct 14; 26(42):1961-5. PMID: 4259326.
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    239. Witte J, Dressler L, Vogel I. [Clinical experiences with ventricle controlled pacemakers]. Z Gesamte Inn Med. 1971 Jan 01; 26(1):22-5. PMID: 5560759.
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