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    Jeremy Reiter, MD, PhD

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentBiochemistry and Biophysics
    Address555 Mission Bay Blvd South
    San Francisco CA 94158
    Phone415-502-8528
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      Collapse Biography 
      Collapse Education and Training
      University of California, San FranciscoM.D. Medicine2001
      University of California, San FranciscoPh.D. Graduate Division (Biochemistry)1999

      Collapse Overview 
      Collapse Overview
      Smith Cardiovascular Research Building
      Room 352G, Box 3120
      555 Mission Bay Blvd South

      Hedgehog, cilia, basal cell carcinoma, medulloblastoma, stem cell, centriole, centrosome, Smoothened, transition zone, Meckel syndrome


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      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Garcia-Gonzalo FR, Reiter JF. Open Sesame: How Transition Fibers and the Transition Zone Control Ciliary Composition. Cold Spring Harb Perspect Biol. 2016 Oct 21. PMID: 27770015.
        View in: PubMed
      2. Garcia G, Reiter JF. A primer on the mouse basal body. Cilia. 2016; 5:17. PMID: 27114821.
        View in: PubMed
      3. Li C, Jensen VL, Park K, Kennedy J, Garcia-Gonzalo FR, Romani M, De Mori R, Bruel AL, Gaillard D, Doray B, Lopez E, Rivière JB, Faivre L, Thauvin-Robinet C, Reiter JF, Blacque OE, Valente EM, Leroux MR. MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone. PLoS Biol. 2016 Mar; 14(3):e1002416. PMID: 26982032.
        View in: PubMed
      4. Dinsmore C, Reiter JF. Endothelial primary cilia inhibit atherosclerosis. EMBO Rep. 2016 Feb; 17(2):156-66. PMID: 26769565.
        View in: PubMed
      5. Yee LE, Garcia-Gonzalo FR, Bowie RV, Li C, Kennedy JK, Ashrafi K, Blacque OE, Leroux MR, Reiter JF. Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling. PLoS Genet. 2015 Nov; 11(11):e1005627. PMID: 26540106; PMCID: PMC4635004.
      6. Vagnozzi AN, Reiter JF, Wong SY. Hair follicle and interfollicular epidermal stem cells make varying contributions to wound regeneration. Cell Cycle. 2015 Nov 2; 14(21):3408-17. PMID: 26398918.
        View in: PubMed
      7. Garcia-Gonzalo FR, Phua SC, Roberson EC, Garcia G, Abedin M, Schurmans S, Inoue T, Reiter JF. Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling. Dev Cell. 2015 Aug 24; 34(4):400-9. PMID: 26305592; PMCID: PMC4557815 [Available on 08/24/16].
      8. Kodani A, Yu TW, Johnson JR, Jayaraman D, Johnson TL, Al-Gazali L, Sztriha L, Partlow JN, Kim H, Krup AL, Dammermann A, Krogan NJ, Walsh CA, Reiter JF. Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication. Elife. 2015; 4. PMID: 26297806; PMCID: PMC4574112.
      9. Yee LE, Reiter JF. Ciliary vesicle formation: a prelude to ciliogenesis. Dev Cell. 2015 Mar 23; 32(6):665-6. PMID: 25805133.
        View in: PubMed
      10. Hu WF, Pomp O, Ben-Omran T, Kodani A, Henke K, Mochida GH, Yu TW, Woodworth MB, Bonnard C, Raj GS, Tan TT, Hamamy H, Masri A, Shboul M, Al Saffar M, Partlow JN, Al-Dosari M, Alazami A, Alowain M, Alkuraya FS, Reiter JF, Harris MP, Reversade B, Walsh CA. Katanin p80 regulates human cortical development by limiting centriole and cilia number. Neuron. 2014 Dec 17; 84(6):1240-57. PMID: 25521379; PMCID: PMC4485387 [Available on 12/17/15].
      11. Ye X, Zeng H, Ning G, Reiter JF, Liu A. C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals. Proc Natl Acad Sci U S A. 2014 Feb 11; 111(6):2164-9. PMID: 24469809; PMCID: PMC3926046.
      12. Santos N, Reiter JF. A central region of Gli2 regulates its localization to the primary cilium and transcriptional activity. J Cell Sci. 2014 Apr 1; 127(Pt 7):1500-10. PMID: 24463817; PMCID: PMC3970560.
      13. Veniaminova NA, Vagnozzi AN, Kopinke D, Do TT, Murtaugh LC, Maillard I, Dlugosz AA, Reiter JF, Wong SY. Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration. Development. 2013 Dec; 140(24):4870-80. PMID: 24198274; PMCID: PMC3848186.
      14. D'Amico E, Gayral S, Massart C, Van Sande J, Reiter JF, Dumont JE, Robaye B, Schurmans S. Thyroid-specific inactivation of KIF3A alters the TSH signaling pathway and leads to hypothyroidism. J Mol Endocrinol. 2013 Jun; 50(3):375-87. PMID: 23511952; PMCID: PMC4404413.
      15. Kodani A, Salomé Sirerol-Piquer M, Seol A, Garcia-Verdugo JM, Reiter JF. Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages. EMBO J. 2013 Feb 20; 32(4):597-607. PMID: 23386061; PMCID: PMC3579144.
      16. Spassov DS, Wong CH, Wong SY, Reiter JF, Moasser MM. Trask loss enhances tumorigenic growth by liberating integrin signaling and growth factor receptor cross-talk in unanchored cells. Cancer Res. 2013 Feb 1; 73(3):1168-79. PMID: 23243018; PMCID: PMC3563920.
      17. Wu VM, Chen SC, Arkin MR, Reiter JF. Small molecule inhibitors of Smoothened ciliary localization and ciliogenesis. Proc Natl Acad Sci U S A. 2012 Aug 21; 109(34):13644-9. PMID: 22864913; PMCID: PMC3427101.
      18. Reiter JF, Blacque OE, Leroux MR. The base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalization. EMBO Rep. 2012 Jul; 13(7):608-18. PMID: 22653444; PMCID: PMC3388784.
      19. Garcia-Gonzalo FR, Reiter JF. Scoring a backstage pass: mechanisms of ciliogenesis and ciliary access. J Cell Biol. 2012 Jun 11; 197(6):697-709. PMID: 22689651; PMCID: PMC3373398.
      20. Saqui-Salces M, Dowdle WE, Reiter JF, Merchant JL. A high-fat diet regulates gastrin and acid secretion through primary cilia. FASEB J. 2012 Aug; 26(8):3127-39. PMID: 22516298; PMCID: PMC3405261.
      21. Hunkapiller J, Shen Y, Diaz A, Cagney G, McCleary D, Ramalho-Santos M, Krogan N, Ren B, Song JS, Reiter JF. Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal. PLoS Genet. 2012; 8(3):e1002576. PMID: 22438827; PMCID: PMC3305387.
      22. Dowdle WE, Robinson JF, Kneist A, Sirerol-Piquer MS, Frints SG, Corbit KC, Zaghloul NA, Zaghloul NA, van Lijnschoten G, Mulders L, Verver DE, Zerres K, Reed RR, Attié-Bitach T, Johnson CA, García-Verdugo JM, Katsanis N, Bergmann C, Reiter JF. Disruption of a ciliary B9 protein complex causes Meckel syndrome. Am J Hum Genet. 2011 Jul 15; 89(1):94-110. PMID: 21763481; PMCID: PMC3135817.
      23. Garcia-Gonzalo FR, Corbit KC, Sirerol-Piquer MS, Ramaswami G, Otto EA, Noriega TR, Seol AD, Robinson JF, Bennett CL, Josifova DJ, García-Verdugo JM, Katsanis N, Hildebrandt F, Reiter JF. A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition. Nat Genet. 2011 Aug; 43(8):776-84. PMID: 21725307; PMCID: PMC3145011.
      24. Sang L, Miller JJ, Corbit KC, Giles RH, Brauer MJ, Otto EA, Baye LM, Wen X, Scales SJ, Kwong M, Huntzicker EG, Sfakianos MK, Sandoval W, Bazan JF, Kulkarni P, Garcia-Gonzalo FR, Seol AD, O'Toole JF, Held S, Reutter HM, Lane WS, Rafiq MA, Noor A, Ansar M, Devi AR, Sheffield VC, Slusarski DC, Vincent JB, Doherty DA, Hildebrandt F, Reiter JF, Jackson PK. Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell. 2011 May 13; 145(4):513-28. PMID: 21565611; PMCID: PMC3383065.
      25. Croyle MJ, Lehman JM, O'Connor AK, Wong SY, Malarkey EB, Iribarne D, Dowdle WE, Schoeb TR, Verney ZM, Athar M, Michaud EJ, Reiter JF, Yoder BK. Role of epidermal primary cilia in the homeostasis of skin and hair follicles. Development. 2011 May; 138(9):1675-85. PMID: 21429982; PMCID: PMC3074444.
      26. Wong SY, Reiter JF. Wounding mobilizes hair follicle stem cells to form tumors. Proc Natl Acad Sci U S A. 2011 Mar 8; 108(10):4093-8. PMID: 21321207; PMCID: PMC3053984.
      27. Reiter JF. Crippling SWI-SNF makes tumors GLI-ful. Nat Med. 2010 Dec; 16(12):1374-6. PMID: 21135845.
        View in: PubMed
      28. Hunkapiller J, Singla V, Seol A, Reiter JF. The ciliogenic protein Oral-Facial-Digital 1 regulates the neuronal differentiation of embryonic stem cells. Stem Cells Dev. 2011 May; 20(5):831-41. PMID: 20873986; PMCID: PMC3128778.
      29. Santos N, Reiter JF. Tilting at nodal windmills: planar cell polarity positions cilia to tell left from right. Dev Cell. 2010 Jul 20; 19(1):5-6. PMID: 20643343; PMCID: PMC3998640.
      30. Reiter JF, de Sauvage FJ. Vive la science! Vive le hérisson! EMBO Rep. 2010 Aug; 11(8):566-8. PMID: 20634805; PMCID: PMC2920439.
      31. Singla V, Romaguera-Ros M, Garcia-Verdugo JM, Reiter JF. Ofd1, a human disease gene, regulates the length and distal structure of centrioles. Dev Cell. 2010 Mar 16; 18(3):410-24. PMID: 20230748; PMCID: PMC2841064.
      32. Walker E, Chang WY, Hunkapiller J, Cagney G, Garcha K, Torchia J, Krogan NJ, Reiter JF, Stanford WL. Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation. Cell Stem Cell. 2010 Feb 5; 6(2):153-66. PMID: 20144788; PMCID: PMC2849004.
      33. Singla V, Hunkapiller J, Santos N, Seol AD, Norman AR, Wakenight P, Skarnes WC, Reiter JF. Floxin, a resource for genetically engineering mouse ESCs. Nat Methods. 2010 Jan; 7(1):50-2. PMID: 19966808; PMCID: PMC2895430.
      34. Wong SY, Seol AD, So PL, Ermilov AN, Bichakjian CK, Epstein EH, Dlugosz AA, Reiter JF. Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis. Nat Med. 2009 Sep; 15(9):1055-61. PMID: 19701205; PMCID: PMC2895420.
      35. Aanstad P, Santos N, Corbit KC, Scherz PJ, Trinh le A, Salvenmoser W, Huisken J, Reiter JF, Stainier DY. The extracellular domain of Smoothened regulates ciliary localization and is required for high-level Hh signaling. Curr Biol. 2009 Jun 23; 19(12):1034-9. PMID: 19464178; PMCID: PMC2892286.
      36. Santos N, Reiter JF. Building it up and taking it down: the regulation of vertebrate ciliogenesis. Dev Dyn. 2008 Aug; 237(8):1972-81. PMID: 18435467; PMCID: PMC3304540.
      37. Reiter JF. A cilium is not a cilium is not a cilium: signaling contributes to ciliary morphological diversity. Dev Cell. 2008 May; 14(5):635-6. PMID: 18477443.
        View in: PubMed
      38. Gaulden J, Reiter JF. Neur-ons and neur-offs: regulators of neural induction in vertebrate embryos and embryonic stem cells. Hum Mol Genet. 2008 Apr 15; 17(R1):R60-6. PMID: 18632699.
        View in: PubMed
      39. Wong SY, Reiter JF. The primary cilium at the crossroads of mammalian hedgehog signaling. Curr Top Dev Biol. 2008; 85:225-60. PMID: 19147008; PMCID: PMC2653622.
      40. Corbit KC, Shyer AE, Dowdle WE, Gaulden J, Singla V, Chen MH, Chuang PT, Reiter JF. Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms. Nat Cell Biol. 2008 Jan; 10(1):70-6. PMID: 18084282.
        View in: PubMed
      41. Reiter JF, Mostov K. Vesicle transport, cilium formation, and membrane specialization: the origins of a sensory organelle. Proc Natl Acad Sci U S A. 2006 Dec 5; 103(49):18383-4. PMID: 17132734; PMCID: PMC1693671.
      42. Singla V, Reiter JF. The primary cilium as the cell's antenna: signaling at a sensory organelle. Science. 2006 Aug 4; 313(5787):629-33. PMID: 16888132.
        View in: PubMed
      43. Reiter JF, Skarnes WC. Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition. Genes Dev. 2006 Jan 1; 20(1):22-7. PMID: 16357211; PMCID: PMC1356097.
      44. May SR, Ashique AM, Karlen M, Wang B, Shen Y, Zarbalis K, Reiter J, Ericson J, Peterson AS. Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli. Dev Biol. 2005 Nov 15; 287(2):378-89. PMID: 16229832.
        View in: PubMed
      45. Corbit KC, Aanstad P, Singla V, Norman AR, Stainier DY, Reiter JF. Vertebrate Smoothened functions at the primary cilium. Nature. 2005 Oct 13; 437(7061):1018-21. PMID: 16136078.
        View in: PubMed
      46. Kikuchi Y, Verkade H, Reiter JF, Kim CH, Chitnis AB, Kuroiwa A, Stainier DY. Notch signaling can regulate endoderm formation in zebrafish. Dev Dyn. 2004 Apr; 229(4):756-62. PMID: 15042699.
        View in: PubMed
      47. Reiter JF, Verkade H, Stainier DY. Bmp2b and Oep promote early myocardial differentiation through their regulation of gata5. Dev Biol. 2001 Jun 15; 234(2):330-8. PMID: 11397003.
        View in: PubMed
      48. Reiter JF, Kikuchi Y, Stainier DY. Multiple roles for Gata5 in zebrafish endoderm formation. Development. 2001 Jan; 128(1):125-35. PMID: 11092818.
        View in: PubMed
      49. Kikuchi Y, Trinh LA, Reiter JF, Alexander J, Yelon D, Stainier DY. The zebrafish bonnie and clyde gene encodes a Mix family homeodomain protein that regulates the generation of endodermal precursors. Genes Dev. 2000 May 15; 14(10):1279-89. PMID: 10817762; PMCID: PMC316618.
      50. Reiter JF, Alexander J, Rodaway A, Yelon D, Patient R, Holder N, Stainier DY. Gata5 is required for the development of the heart and endoderm in zebrafish. Genes Dev. 1999 Nov 15; 13(22):2983-95. PMID: 10580005; PMCID: PMC317161.
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