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    Boris Bastian, MD, PhD

    SchoolUCSF School of Medicine
    Address1450 3rd Street
    San Francisco CA 94158

       ORNG Applications 
       Awarded Grants
       Global Health

      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Machan S, Molina-Ruiz AM, Fernández-Aceñero MJ, Encabo B, LeBoit P, Bastian BC, Requena L. Metastatic Melanoma in Association With a Giant Congenital Melanocytic Nevus in an Adult: Controversial CGH Findings. Am J Dermatopathol. 2015 Jun; 37(6):487-94.
        View in: PubMed
      2. Algazi AP, Cha E, Ortiz-Urda SM, McCalmont T, Bastian BC, Hwang J, Pampaloni MH, Behr S, Chong K, Cortez B, Quiroz A, Coakley F, Liu S, Daud AI. The combination of axitinib followed by paclitaxel/carboplatin yields extended survival in advanced BRAF wild-type melanoma: results of a clinical/correlative prospective phase II clinical trial. Br J Cancer. 2015 Apr 14; 112(8):1326-31.
        View in: PubMed
      3. Carvajal RD, Lawrence DP, Weber JS, Gajewski TF, Gonzalez R, Lutzky J, O'Day SJ, Hamid O, Wolchok JD, Chapman PB, Sullivan RJ, Teitcher JB, Ramaiya N, Giobbie-Hurder A, Antonescu CR, Heinrich MC, Bastian BC, Corless CL, Fletcher JA, Hodi FS. Phase II Study of Nilotinib in Melanoma Harboring KIT Alterations Following Progression to Prior KIT Inhibition. Clin Cancer Res. 2015 May 15; 21(10):2289-96.
        View in: PubMed
      4. Yeh I, de la Fouchardiere A, Pissaloux D, Mully TW, Garrido MC, Vemula SS, Busam KJ, LeBoit PE, McCalmont TH, Bastian BC. Clinical, Histopathologic, and Genomic Features of Spitz Tumors With ALK Fusions. Am J Surg Pathol. 2015 Jan 19.
        View in: PubMed
      5. Botton T, Yeh I, Bastian BC. Melanoma BRAF Fusions-Letter. Clin Cancer Res. 2014 Dec 15; 20(24):6631.
        View in: PubMed
      6. Lowdon RF, Zhang B, Bilenky M, Mauro T, Li D, Gascard P, Sigaroudinia M, Farnham PJ, Bastian BC, Tlsty TD, Marra MA, Hirst M, Costello JF, Wang T, Cheng JB. Regulatory network decoded from epigenomes of surface ectoderm-derived cell types. Nat Commun. 2014; 5:5442.
        View in: PubMed
      7. Esteve-Puig R, Gil R, González-Sánchez E, Bech-Serra JJ, Grueso J, Hernández-Losa J, Moliné T, Canals F, Ferrer B, Cortés J, Bastian B, Ramón Y Cajal S, Martín-Caballero J, Flores JM, Vivancos A, García-Patos V, Recio JÁ. A mouse model uncovers LKB1 as an UVB-induced DNA damage sensor mediating CDKN1A (p21WAF1/CIP1) degradation. PLoS Genet. 2014 Oct; 10(10):e1004721.
        View in: PubMed PMC4199501
      8. Luke JJ, Triozzi PL, McKenna KC, Van Meir EG, Gershenwald JE, Bastian BC, Gutkind JS, Bowcock AM, Streicher HZ, Patel PM, Sato T, Sossman JA, Sznol M, Welch J, Thurin M, Selig S, Flaherty KT, Carvajal RD. Biology of advanced uveal melanoma and next steps for clinical therapeutics. Pigment Cell Melanoma Res. 2015 Mar; 28(2):135-47.
        View in: PubMed
      9. Yeh I, Mully TW, Wiesner T, Vemula SS, Mirza SA, Sparatta AJ, McCalmont TH, Bastian BC, LeBoit PE. Ambiguous melanocytic tumors with loss of 3p21. Am J Surg Pathol. 2014 Aug; 38(8):1088-95.
        View in: PubMed PMC4101029
      10. North JP, Garrido MC, Kolaitis NA, LeBoit PE, McCalmont TH, Bastian BC. Fluorescence in situ hybridization as an ancillary tool in the diagnosis of ambiguous melanocytic neoplasms: a review of 804 cases. Am J Surg Pathol. 2014 Jun; 38(6):824-31.
        View in: PubMed
      11. Yu FX, Luo J, Mo JS, Liu G, Kim YC, Meng Z, Zhao L, Peyman G, Ouyang H, Jiang W, Zhao J, Chen X, Zhang L, Wang CY, Bastian BC, Zhang K, Guan KL. Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP. Cancer Cell. 2014 Jun 16; 25(6):822-30.
        View in: PubMed PMC4075337
      12. Menzel M, Meckbach D, Weide B, Toussaint NC, Schilbach K, Noor S, Eigentler T, Ikenberg K, Busch C, Quintanilla-Martinez L, Kohlhofer U, Göke A, Göke F, Handgretinger R, Ottmann C, Bastian BC, Garbe C, Röcken M, Perner S, Kohlbacher O, Bauer J. In melanoma, Hippo signaling is affected by copy number alterations and YAP1 overexpression impairs patient survival. Pigment Cell Melanoma Res. 2014 Jul; 27(4):671-3.
        View in: PubMed
      13. Wiesner T, He J, Yelensky R, Esteve-Puig R, Botton T, Yeh I, Lipson D, Otto G, Brennan K, Murali R, Garrido M, Miller VA, Ross JS, Berger MF, Sparatta A, Palmedo G, Cerroni L, Busam KJ, Kutzner H, Cronin MT, Stephens PJ, Bastian BC. Kinase fusions are frequent in Spitz tumours and spitzoid melanomas. Nat Commun. 2014; 5:3116.
        View in: PubMed PMC4084638
      14. North JP, Vemula SS, Bastian BC. Chromosomal copy number analysis in melanoma diagnostics. Methods Mol Biol. 2014; 1102:199-226.
        View in: PubMed
      15. Bastian BC. The molecular pathology of melanoma: an integrated taxonomy of melanocytic neoplasia. Annu Rev Pathol. 2014; 9:239-71.
        View in: PubMed
      16. Simpson RM, Bastian BC, Michael HT, Webster JD, Prasad ML, Conway CM, Prieto VM, Gary JM, Goldschmidt MH, Esplin DG, Smedley RC, Piris A, Meuten DJ, Kiupel M, Lee CC, Ward JM, Dwyer JE, Davis BJ, Anver MR, Molinolo AA, Hoover SB, Rodriguez-Canales J, Hewitt SM. Sporadic naturally occurring melanoma in dogs as a preclinical model for human melanoma. Pigment Cell Melanoma Res. 2014 Jan; 27(1):37-47.
        View in: PubMed PMC4066658
      17. Chen X, Wu Q, Tan L, Porter D, Jager MJ, Emery C, Bastian BC. Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations. Oncogene. 2014 Sep 25; 33(39):4724-34.
        View in: PubMed
      18. Botton T, Yeh I, Nelson T, Vemula SS, Sparatta A, Garrido MC, Allegra M, Rocchi S, Bahadoran P, McCalmont TH, LeBoit PE, Burton EA, Bollag G, Ballotti R, Bastian BC. Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy. Pigment Cell Melanoma Res. 2013 Nov; 26(6):845-51.
        View in: PubMed PMC3808507
      19. Bastian BC, Esteve-Puig R. Targeting activated KIT signaling for melanoma therapy. J Clin Oncol. 2013 Sep 10; 31(26):3288-90.
        View in: PubMed
      20. Cronin JC, Watkins-Chow DE, Incao A, Hasskamp JH, Schönewolf N, Aoude LG, Hayward NK, Bastian BC, Dummer R, Loftus SK, Pavan WJ. SOX10 ablation arrests cell cycle, induces senescence, and suppresses melanomagenesis. Cancer Res. 2013 Sep 15; 73(18):5709-18.
        View in: PubMed PMC3803156
      21. Lyons J, Bastian BC, McCormick F. MC1R and cAMP signaling inhibit cdc25B activity and delay cell cycle progression in melanoma cells. Proc Natl Acad Sci U S A. 2013 Aug 20; 110(34):13845-50.
        View in: PubMed PMC3752210
      22. Fleming JL, Dworkin AM, Allain DC, Fernandez S, Wei L, Peters SB, Iwenofu OH, Ridd K, Bastian BC, Toland AE. Allele-specific imbalance mapping identifies HDAC9 as a candidate gene for cutaneous squamous cell carcinoma. Int J Cancer. 2014 Jan 1; 134(1):244-8.
        View in: PubMed PMC3831612
      23. Roesch A, Vultur A, Bogeski I, Wang H, Zimmermann KM, Speicher D, Körbel C, Laschke MW, Gimotty PA, Philipp SE, Krause E, Pätzold S, Villanueva J, Krepler C, Fukunaga-Kalabis M, Hoth M, Bastian BC, Vogt T, Herlyn M. Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells. Cancer Cell. 2013 Jun 10; 23(6):811-25.
        View in: PubMed PMC3810180
      24. Yeh I, von Deimling A, Bastian BC. Clonal BRAF mutations in melanocytic nevi and initiating role of BRAF in melanocytic neoplasia. J Natl Cancer Inst. 2013 Jun 19; 105(12):917-9.
        View in: PubMed PMC3687371
      25. Suri P, Bull N, Worthington A, Gunawaran P, Reeves G, Bastian B, Collins N. Audit of the aetiology and prevalence of pulmonary hypertension in a tertiary hospital setting. Intern Med J. 2013 Mar; 43(3):323-7.
        View in: PubMed
      26. Wiesner T, Murali R, Fried I, Cerroni L, Busam K, Kutzner H, Bastian BC. A distinct subset of atypical Spitz tumors is characterized by BRAF mutation and loss of BAP1 expression. Am J Surg Pathol. 2012 Jun; 36(6):818-30.
        View in: PubMed PMC3354018
      27. Murali R, Wiesner T, Rosenblum MK, Bastian BC. GNAQ and GNA11 mutations in melanocytomas of the central nervous system. Acta Neuropathol. 2012 Mar; 123(3):457-9.
        View in: PubMed PMC3495609
      28. Griewank KG, Yu X, Khalili J, Sozen MM, Stempke-Hale K, Bernatchez C, Wardell S, Bastian BC, Woodman SE. Genetic and molecular characterization of uveal melanoma cell lines. Pigment Cell Melanoma Res. 2012 Mar; 25(2):182-7.
        View in: PubMed PMC3288394
      29. Minor DR, Kashani-Sabet M, Garrido M, O'Day SJ, Hamid O, Bastian BC. Sunitinib therapy for melanoma patients with KIT mutations. Clin Cancer Res. 2012 Mar 1; 18(5):1457-63.
        View in: PubMed
      30. Daud A, Bastian BC. Beyond BRAF in melanoma. Curr Top Microbiol Immunol. 2012; 355:99-117.
        View in: PubMed
      31. McCalmont TH, Bastian BC. An unconventional deep penetrating melanocytic nevus with microscopic involvement of regional lymph nodes. J Cutan Pathol. 2012 Jan; 39(1):25-8.
        View in: PubMed
      32. Feito-Rodríguez M, de Lucas-Laguna R, Bastian BC, Leboit P, González-Beato MJ, López-Gutiérrez JC, Requena L, Pizarro A. Nodular lesions arising in a large congenital melanocytic naevus in a newborn with eruptive disseminated Spitz naevi. Br J Dermatol. 2011 Nov; 165(5):1138-42.
        View in: PubMed
      33. Jalas JR, Vemula S, Bezrookove V, Leboit PE, Simko JP, Bastian BC. Metastatic melanoma with striking adenocarcinomatous differentiation illustrating phenotypic plasticity in melanoma. Am J Surg Pathol. 2011 Sep; 35(9):1413-8.
        View in: PubMed PMC3319763
      34. Wiesner T, Obenauf AC, Murali R, Fried I, Griewank KG, Ulz P, Windpassinger C, Wackernagel W, Loy S, Wolf I, Viale A, Lash AE, Pirun M, Socci ND, Rütten A, Palmedo G, Abramson D, Offit K, Ott A, Becker JC, Cerroni L, Kutzner H, Bastian BC, Speicher MR. Germline mutations in BAP1 predispose to melanocytic tumors. Nat Genet. 2011 Oct; 43(10):1018-21.
        View in: PubMed PMC3328403
      35. Ahronowitz IZ, Daud AI, Leong SP, Shue EH, Bastian BC, McCalmont TH, Yu SS. An isolated Merkel cell carcinoma metastasis at a distant cutaneous site presenting as a second 'primary' tumor. J Cutan Pathol. 2011 Oct; 38(10):801-7.
        View in: PubMed
      36. Kumar SM, Zhang G, Bastian BC, Arcasoy MO, Karande P, Pushparajan A, Acs G, Xu X. Erythropoietin receptor contributes to melanoma cell survival in vivo. Oncogene. 2012 Mar 29; 31(13):1649-60.
        View in: PubMed PMC3441831
      37. Whiteman DC, Pavan WJ, Bastian BC. The melanomas: a synthesis of epidemiological, clinical, histopathological, genetic, and biological aspects, supporting distinct subtypes, causal pathways, and cells of origin. Pigment Cell Melanoma Res. 2011 Oct; 24(5):879-97.
        View in: PubMed PMC3395885
      38. North JP, Vetto JT, Murali R, White KP, White CR, Bastian BC. Assessment of copy number status of chromosomes 6 and 11 by FISH provides independent prognostic information in primary melanoma. Am J Surg Pathol. 2011 Aug; 35(8):1146-50.
        View in: PubMed PMC4153784
      39. Carvajal RD, Antonescu CR, Wolchok JD, Chapman PB, Roman RA, Teitcher J, Panageas KS, Busam KJ, Chmielowski B, Lutzky J, Pavlick AC, Fusco A, Cane L, Takebe N, Vemula S, Bouvier N, Bastian BC, Schwartz GK. KIT as a therapeutic target in metastatic melanoma. JAMA. 2011 Jun 8; 305(22):2327-34.
        View in: PubMed PMC3986039
      40. McCalmont TH, Vemula S, Sands P, Bastian BC. Molecular-microscopical correlation in dermatopathology. J Cutan Pathol. 2011 Apr; 38(4):324-6, 323.
        View in: PubMed PMC3339263
      41. Bauer J, Büttner P, Murali R, Okamoto I, Kolaitis NA, Landi MT, Scolyer RA, Bastian BC. BRAF mutations in cutaneous melanoma are independently associated with age, anatomic site of the primary tumor, and the degree of solar elastosis at the primary tumor site. Pigment Cell Melanoma Res. 2011 Apr; 24(2):345-51.
        View in: PubMed PMC3107974
      42. Broekaert SM, Roy R, Okamoto I, van den Oord J, Bauer J, Garbe C, Barnhill RL, Busam KJ, Cochran AJ, Cook MG, Elder DE, McCarthy SW, Mihm MC, Schadendorf D, Scolyer RA, Spatz A, Bastian BC. Genetic and morphologic features for melanoma classification. Pigment Cell Melanoma Res. 2010 Dec; 23(6):763-70.
        View in: PubMed PMC3107973
      43. Van Raamsdonk CD, Griewank KG, Crosby MB, Garrido MC, Vemula S, Wiesner T, Obenauf AC, Wackernagel W, Green G, Bouvier N, Sozen MM, Baimukanova G, Roy R, Heguy A, Dolgalev I, Khanin R, Busam K, Speicher MR, O'Brien J, Bastian BC. Mutations in GNA11 in uveal melanoma. N Engl J Med. 2010 Dec 2; 363(23):2191-9.
        View in: PubMed PMC3107972
      44. Beaudry VG, Jiang D, Dusek RL, Park EJ, Knezevich S, Ridd K, Vogel H, Bastian BC, Attardi LD. Loss of the p53/p63 regulated desmosomal protein Perp promotes tumorigenesis. PLoS Genet. 2010 Oct; 6(10):e1001168.
        View in: PubMed PMC2958815
      45. Dworkin AM, Ridd K, Bautista D, Allain DC, Iwenofu OH, Roy R, Bastian BC, Toland AE. Germline variation controls the architecture of somatic alterations in tumors. PLoS Genet. 2010 Sep; 6(9):e1001136.
        View in: PubMed PMC2944791
      46. Griewank KG, Bastian BC. Comment on "Cutaneous melanoma in childhood and adolescence shows frequent loss of INK4A and gain of KIT". J Invest Dermatol. 2010 Sep; 130(9):2330-1; author reply 2331-2.
        View in: PubMed
      47. Flaherty KT, Hodi FS, Bastian BC. Mutation-driven drug development in melanoma. Curr Opin Oncol. 2010 May; 22(3):178-83.
        View in: PubMed PMC3107971
      48. Gerami P, Pouryazdanparast P, Vemula S, Bastian BC. Molecular analysis of a case of nevus of ota showing progressive evolution to melanoma with intermediate stages resembling cellular blue nevus. Am J Dermatopathol. 2010 May; 32(3):301-5.
        View in: PubMed
      49. Dalton SR, Gerami P, Kolaitis NA, Charzan S, Werling R, LeBoit PE, Bastian BC. Use of fluorescence in situ hybridization (FISH) to distinguish intranodal nevus from metastatic melanoma. Am J Surg Pathol. 2010 Feb; 34(2):231-7.
        View in: PubMed PMC2831773
      50. Garrido MC, Bastian BC. KIT as a therapeutic target in melanoma. J Invest Dermatol. 2010 Jan; 130(1):20-7.
        View in: PubMed PMC2831053
      51. Fisher DE, Barnhill R, Hodi FS, Herlyn M, Merlino G, Medrano E, Bastian B, Landi MT, Landi TM, Sosman J. Melanoma from bench to bedside: meeting report from the 6th international melanoma congress. Pigment Cell Melanoma Res. 2010 Feb; 23(1):14-26.
        View in: PubMed
      52. Ridd K, Bastian BC. Somatic mutation of epidermal growth factor receptor in a small subset of cutaneous squamous cell carcinoma. J Invest Dermatol. 2010 Mar; 130(3):901-3.
        View in: PubMed PMC2825112
      53. Yeh I, Bastian BC. Genome-wide associations studies for melanoma and nevi. Pigment Cell Melanoma Res. 2009 Oct; 22(5):527-8.
        View in: PubMed PMC2841523
      54. Harradine KA, Ridd K, Saunier EF, Clermont FF, Perez-Losada J, Moore DH, Epstein EH, Bastian BC, Akhurst RJ. Elevated cutaneous Smad activation associates with enhanced skin tumor susceptibility in organ transplant recipients. Clin Cancer Res. 2009 Aug 15; 15(16):5101-7.
        View in: PubMed PMC2812428
      55. Bauer J, Kilic E, Vaarwater J, Bastian BC, Garbe C, de Klein A. Oncogenic GNAQ mutations are not correlated with disease-free survival in uveal melanoma. Br J Cancer. 2009 Sep 1; 101(5):813-5.
        View in: PubMed PMC2736834
      56. Gerami P, Jewell SS, Morrison LE, Blondin B, Schulz J, Ruffalo T, Matushek P, Legator M, Jacobson K, Dalton SR, Charzan S, Kolaitis NA, Guitart J, Lertsbarapa T, Boone S, LeBoit PE, Bastian BC. Fluorescence in situ hybridization (FISH) as an ancillary diagnostic tool in the diagnosis of melanoma. Am J Surg Pathol. 2009 Aug; 33(8):1146-56.
        View in: PubMed
      57. Bauer J, Weng J, Kebebew E, Soares P, Trovisco V, Bastian BC. Germline variation of the melanocortin-1 receptor does not explain shared risk for melanoma and thyroid cancer. Exp Dermatol. 2009 Jun; 18(6):548-52.
        View in: PubMed PMC2862686
      58. Ridd K, Vemula S, Bastian BC. Absence of somatic mutations of NEMO in keratoacanthoma. J Invest Dermatol. 2009 Oct; 129(10):2518-20.
        View in: PubMed PMC2823812
      59. Cronin JC, Wunderlich J, Loftus SK, Prickett TD, Wei X, Ridd K, Vemula S, Burrell AS, Agrawal NS, Lin JC, Banister CE, Buckhaults P, Rosenberg SA, Bastian BC, Pavan WJ, Samuels Y. Frequent mutations in the MITF pathway in melanoma. Pigment Cell Melanoma Res. 2009 Aug; 22(4):435-44.
        View in: PubMed PMC2728363
      60. Gartside MG, Chen H, Ibrahimi OA, Byron SA, Curtis AV, Wellens CL, Bengston A, Yudt LM, Eliseenkova AV, Ma J, Curtin JA, Hyder P, Harper UL, Riedesel E, Mann GJ, Trent JM, Bastian BC, Meltzer PS, Mohammadi M, Pollock PM. Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma. Mol Cancer Res. 2009 Jan; 7(1):41-54.
        View in: PubMed
      61. Van Raamsdonk CD, Bezrookove V, Green G, Bauer J, Gaugler L, O'Brien JM, Simpson EM, Barsh GS, Bastian BC. Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. Nature. 2009 Jan 29; 457(7229):599-602.
        View in: PubMed PMC2696133
      62. Ridd K, Yu S, Bastian BC. The presence of polyomavirus in non-melanoma skin cancer in organ transplant recipients is rare. J Invest Dermatol. 2009 Jan; 129(1):250-2.
        View in: PubMed PMC2837873
      63. Viros A, Fridlyand J, Bauer J, Lasithiotakis K, Garbe C, Pinkel D, Bastian BC. Improving melanoma classification by integrating genetic and morphologic features. PLoS Med. 2008 Jun 3; 5(6):e120.
        View in: PubMed PMC2408611
      64. Lutzky J, Bauer J, Bastian BC. Dose-dependent, complete response to imatinib of a metastatic mucosal melanoma with a K642E KIT mutation. Pigment Cell Melanoma Res. 2008 Aug; 21(4):492-3.
        View in: PubMed
      65. Freedberg DE, Rigas SH, Russak J, Gai W, Kaplow M, Osman I, Turner F, Randerson-Moor JA, Houghton A, Busam K, Timothy Bishop D, Bastian BC, Newton-Bishop JA, Polsky D. Frequent p16-independent inactivation of p14ARF in human melanoma. J Natl Cancer Inst. 2008 Jun 4; 100(11):784-95.
        View in: PubMed
      66. Fargnoli MC, Fargnoli MC, Pike K, Pfeiffer RM, Tsang S, Rozenblum E, Munroe DJ, Golubeva Y, Calista D, Seidenari S, Massi D, Carli P, Bauer J, Elder DE, Bastian BC, Peris K, Landi MT. MC1R variants increase risk of melanomas harboring BRAF mutations. J Invest Dermatol. 2008 Oct; 128(10):2485-90.
        View in: PubMed PMC2835495
      67. North JP, Kageshita T, Pinkel D, LeBoit PE, Bastian BC. Distribution and significance of occult intraepidermal tumor cells surrounding primary melanoma. J Invest Dermatol. 2008 Aug; 128(8):2024-30.
        View in: PubMed PMC2825251
      68. Delmas V, Beermann F, Martinozzi S, Carreira S, Ackermann J, Kumasaka M, Denat L, Goodall J, Luciani F, Viros A, Demirkan N, Bastian BC, Goding CR, Larue L. Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development. Genes Dev. 2007 Nov 15; 21(22):2923-35.
        View in: PubMed PMC2049194
      69. Muchemwa FC, Ma D, Inoue Y, Curtin JA, Bastian BC, Ihn H, Kageshita T. Constitutive activation of the phosphatidyl inositol 3 kinase signalling pathway in acral lentiginous melanoma. Br J Dermatol. 2008 Feb; 158(2):411-3.
        View in: PubMed
      70. Bauer J, Bastian BC. [DNA copy number changes in the diagnosis of melanocytic tumors]. Pathologe. 2007 Nov; 28(6):464-73.
        View in: PubMed
      71. Kebebew E, Weng J, Bauer J, Ranvier G, Clark OH, Duh QY, Shibru D, Bastian B, Griffin A. The prevalence and prognostic value of BRAF mutation in thyroid cancer. Ann Surg. 2007 Sep; 246(3):466-70; discussion 470-1.
        View in: PubMed PMC1959359
      72. Curtin JA, Pinkel D, Bastian BC. Absence of PDGFRA mutations in primary melanoma. J Invest Dermatol. 2008 Feb; 128(2):488-9.
        View in: PubMed
      73. Bastian BC, Pinkel D. Expanding the genetic spectrum of pigmentation. Pigment Cell Melanoma Res. 2008 Oct; 21(5):507-8.
        View in: PubMed
      74. Kim RD, Curtin JA, Bastian BC. Lack of somatic alterations of MC1R in primary melanoma. Pigment Cell Melanoma Res. 2008 Oct; 21(5):579-82.
        View in: PubMed PMC2825252
      75. Murata H, Ashida A, Takata M, Yamaura M, Bastian BC, Saida T. Establishment of a novel melanoma cell line SMYM-PRGP showing cytogenetic and biological characteristics of the radial growth phase of acral melanomas. Cancer Sci. 2007 Jul; 98(7):958-63.
        View in: PubMed
      76. Thorns C, Bastian B, Pinkel D, Roydasgupta R, Fridlyand J, Merz H, Krokowski M, Bernd HW, Feller AC. Chromosomal aberrations in angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma unspecified: A matrix-based CGH approach. Genes Chromosomes Cancer. 2007 Jan; 46(1):37-44.
        View in: PubMed
      77. Dumaz N, Hayward R, Martin J, Ogilvie L, Hedley D, Curtin JA, Bastian BC, Springer C, Marais R. In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signaling. Cancer Res. 2006 Oct 1; 66(19):9483-91.
        View in: PubMed
      78. Denoyelle C, Abou-Rjaily G, Bezrookove V, Verhaegen M, Johnson TM, Fullen DR, Pointer JN, Gruber SB, Su LD, Nikiforov MA, Kaufman RJ, Bastian BC, Soengas MS. Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway. Nat Cell Biol. 2006 Oct; 8(10):1053-63.
        View in: PubMed
      79. Curtin JA, Busam K, Pinkel D, Bastian BC. Somatic activation of KIT in distinct subtypes of melanoma. J Clin Oncol. 2006 Sep 10; 24(26):4340-6.
        View in: PubMed
      80. Bauer J, Curtin JA, Pinkel D, Bastian BC. Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations. J Invest Dermatol. 2007 Jan; 127(1):179-82.
        View in: PubMed
      81. Landi MT, Bauer J, Pfeiffer RM, Elder DE, Hulley B, Minghetti P, Calista D, Kanetsky PA, Pinkel D, Bastian BC. MC1R germline variants confer risk for BRAF-mutant melanoma. Science. 2006 Jul 28; 313(5786):521-2.
        View in: PubMed
      82. Curtin JA, Stark MS, Pinkel D, Hayward NK, Bastian BC. PI3-kinase subunits are infrequent somatic targets in melanoma. J Invest Dermatol. 2006 Jul; 126(7):1660-3.
        View in: PubMed
      83. Bauer J, Bastian BC. Distinguishing melanocytic nevi from melanoma by DNA copy number changes: comparative genomic hybridization as a research and diagnostic tool. Dermatol Ther. 2006 Jan-Feb; 19(1):40-9.
        View in: PubMed
      84. Curtin JA, Fridlyand J, Kageshita T, Patel HN, Busam KJ, Kutzner H, Cho KH, Aiba S, Bröcker EB, LeBoit PE, Pinkel D, Bastian BC. Distinct sets of genetic alterations in melanoma. N Engl J Med. 2005 Nov 17; 353(20):2135-47.
        View in: PubMed
      85. Maize JC, McCalmont TH, Carlson JA, Busam KJ, Kutzner H, Bastian BC. Genomic analysis of blue nevi and related dermal melanocytic proliferations. Am J Surg Pathol. 2005 Sep; 29(9):1214-20.
        View in: PubMed
      86. Sahara LY, Bastian BC, Bruckner AL. Coalescing, nevoid papules in an infant. Arch Dermatol. 2005 Jul; 141(7):897-902.
        View in: PubMed
      87. Bauer J, Bastian B. Genomic analysis of melanocytic neoplasia. Adv Dermatol. 2005; 21:81-99.
        View in: PubMed
      88. Hantschke M, Bastian BC, LeBoit PE. Consumption of the epidermis: a diagnostic criterion for the differential diagnosis of melanoma and Spitz nevus. Am J Surg Pathol. 2004 Dec; 28(12):1621-5.
        View in: PubMed
      89. Bastian BC. Molecular genetics of melanocytic neoplasia: practical applications for diagnosis. Pathology. 2004 Oct; 36(5):458-61.
        View in: PubMed
      90. Maldonado JL, Timmerman L, Fridlyand J, Bastian BC. Mechanisms of cell-cycle arrest in Spitz nevi with constitutive activation of the MAP-kinase pathway. Am J Pathol. 2004 May; 164(5):1783-7.
        View in: PubMed PMC1615645
      91. Maldonado JL, Fridlyand J, Patel H, Jain AN, Busam K, Kageshita T, Ono T, Albertson DG, Pinkel D, Bastian BC. Determinants of BRAF mutations in primary melanomas. J Natl Cancer Inst. 2003 Dec 17; 95(24):1878-90.
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      92. Bastian BC, Olshen AB, LeBoit PE, Pinkel D. Classifying melanocytic tumors based on DNA copy number changes. Am J Pathol. 2003 Nov; 163(5):1765-70.
        View in: PubMed PMC1892437
      93. Dalton SR, Fillman EP, Altman CE, Gardner TL, Davis TL, Bastian BC, Libow LF, Elston DM. Atypical junctional melanocytic proliferations in benign lichenoid keratosis. Hum Pathol. 2003 Jul; 34(7):706-9.
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      94. Bastian BC. Understanding the progression of melanocytic neoplasia using genomic analysis: from fields to cancer. Oncogene. 2003 May 19; 22(20):3081-6.
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      95. Bastian BC. Hypothesis: a role for telomere crisis in spontaneous regression of melanoma. Arch Dermatol. 2003 May; 139(5):667-8.
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      96. Bastian BC. The longer your telomeres, the larger your nevus? Am J Dermatopathol. 2003 Feb; 25(1):83-4.
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      97. Takata M, Maruo K, Kageshita T, Ikeda S, Ono T, Shirasaki F, Takehara K, Bastian BC. Two cases of unusual acral melanocytic tumors: illustration of molecular cytogenetics as a diagnostic tool. Hum Pathol. 2003 Jan; 34(1):89-92.
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      98. Buckley PG, Mantripragada KK, Benetkiewicz M, Tapia-Páez I, Diaz De Ståhl T, Rosenquist M, Ali H, Jarbo C, De Bustos C, Hirvelä C, Sinder Wilén B, Fransson I, Thyr C, Johnsson BI, Bruder CE, Menzel U, Hergersberg M, Mandahl N, Blennow E, Wedell A, Beare DM, Collins JE, Dunham I, Albertson D, Pinkel D, Bastian BC, Faruqi AF, Lasken RS, Ichimura K, Collins VP, Dumanski JP. A full-coverage, high-resolution human chromosome 22 genomic microarray for clinical and research applications. Hum Mol Genet. 2002 Dec 1; 11(25):3221-9.
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      99. Bastian BC, Xiong J, Frieden IJ, Williams ML, Chou P, Busam K, Pinkel D, LeBoit PE. Genetic changes in neoplasms arising in congenital melanocytic nevi: differences between nodular proliferations and melanomas. Am J Pathol. 2002 Oct; 161(4):1163-9.
        View in: PubMed PMC1867277
      100. Sauter ER, Yeo UC, von Stemm A, Zhu W, Litwin S, Tichansky DS, Pistritto G, Nesbit M, Pinkel D, Herlyn M, Bastian BC. Cyclin D1 is a candidate oncogene in cutaneous melanoma. Cancer Res. 2002 Jun 1; 62(11):3200-6.
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      101. Harvell JD, Bastian BC, LeBoit PE. Persistent (recurrent) Spitz nevi: a histopathologic, immunohistochemical, and molecular pathologic study of 22 cases. Am J Surg Pathol. 2002 May; 26(5):654-61.
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      102. You MJ, Castrillon DH, Bastian BC, O'Hagan RC, Bosenberg MW, Parsons R, Chin L, DePinho RA. Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice. Proc Natl Acad Sci U S A. 2002 Feb 5; 99(3):1455-60.
        View in: PubMed PMC122212
      103. Bastian BC. Molecular cytogenetics as a diagnostic tool for typing melanocytic tumors. Recent Results Cancer Res. 2002; 160:92-9.
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      104. Bastian BC, LeBoit PE, Pinkel D. Genomic approaches to skin cancer diagnosis. Arch Dermatol. 2001 Nov; 137(11):1507-11.
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      105. Polsky D, Bastian BC, Hazan C, Melzer K, Pack J, Houghton A, Busam K, Cordon-Cardo C, Osman I. HDM2 protein overexpression, but not gene amplification, is related to tumorigenesis of cutaneous melanoma. Cancer Res. 2001 Oct 15; 61(20):7642-6.
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      106. Bardeesy N, Bastian BC, Hezel A, Pinkel D, DePinho RA, Chin L. Dual inactivation of RB and p53 pathways in RAS-induced melanomas. Mol Cell Biol. 2001 Mar; 21(6):2144-53.
        View in: PubMed PMC86838
      107. Bastian BC, LeBoit PE, Pinkel D. Mutations and copy number increase of HRAS in Spitz nevi with distinctive histopathological features. Am J Pathol. 2000 Sep; 157(3):967-72.
        View in: PubMed PMC1885704
      108. Bastian BC, Kashani-Sabet M, Hamm H, Godfrey T, Moore DH, Bröcker EB, LeBoit PE, Pinkel D. Gene amplifications characterize acral melanoma and permit the detection of occult tumor cells in the surrounding skin. Cancer Res. 2000 Apr 1; 60(7):1968-73.
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      109. Bastian BC, Wesselmann U, Pinkel D, Leboit PE. Molecular cytogenetic analysis of Spitz nevi shows clear differences to melanoma. J Invest Dermatol. 1999 Dec; 113(6):1065-9.
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      110. Bastian BC, Kutzner H, Yen Ts, LeBoit PE. Signet-ring cell formation in cutaneous neoplasms. J Am Acad Dermatol. 1999 Oct; 41(4):606-13.
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      111. Haferkamp B, Bastian BC, Bröcker EB, Hamm H. [Pilomatrix carcinoma in an unusual location. Case report and review of the literature]. Hautarzt. 1999 May; 50(5):355-9.
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      112. Wesselmann U, Becker LR, Bröcker EB, LeBoit PE, Bastian BC. Eosinophilic globules in spitz nevi: no evidence for apoptosis. Am J Dermatopathol. 1998 Dec; 20(6):551-4.
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      113. Becker LR, Bastian BC, Wesselmann U, Karl S, Hamm H, Bröcker EB. Paraneoplastic pemphigus treated with dexamethasone/ cyclophosphamide pulse therapy. Eur J Dermatol. 1998 Dec; 8(8):551-3.
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      114. Bastian BC, LeBoit PE, Hamm H, Bröcker EB, Pinkel D. Chromosomal gains and losses in primary cutaneous melanomas detected by comparative genomic hybridization. Cancer Res. 1998 May 15; 58(10):2170-5.
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      115. Bastian BC, Bröcker EB. Adult rhabdomyoma of the lip. Am J Dermatopathol. 1998 Feb; 20(1):61-4.
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      116. Bastian BC, Ott G, Müller-Deubert S, Bröcker EB, Müller-Hermelink HK. Primary cutaneous natural killer/T-cell lymphoma. Arch Dermatol. 1998 Jan; 134(1):109-11.
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      117. Ott G, Bastian BC, Katzenberger T, Decoteau JF, Kalla J, Rosenwald A, Weissinger F, Ott MM, Kadin ME, Müller-Hermelink HK. A lymphohistiocytic variant of anaplastic large cell lymphoma with demonstration of the t(2;5)(p23;q35) chromosome translocation. Br J Haematol. 1998 Jan; 100(1):187-90.
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      118. Dummer W, Bröcker EB, Bastian BC. Elevated serum levels of soluble CD30 are associated with atopic dermatitis, but not with respiratory atopic disorders and allergic contact dermatitis. Br J Dermatol. 1997 Aug; 137(2):185-7.
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      119. Bastian BC, Kreipe HH, Bröcker EB. Primary neuroendocrine carcinoma of the skin with an unusual follicular lymphocytic infiltrate of the dermis. Am J Dermatopathol. 1996 Dec; 18(6):625-8.
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      120. Spatz A, Ruiter D, Hardmeier T, Renard N, Wechsler J, Bailly C, Avril MF, Kwee H, Bastian BC, Hill C, De Potter C, Prade M. Melanoma in childhood: an EORTC-MCG multicenter study on the clinico-pathological aspects. Int J Cancer. 1996 Nov 4; 68(3):317-24.
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      121. Schmidt E, Bastian B, Dummer R, Tony HP, Bröcker EB, Zillikens D. Detection of elevated levels of IL-4, IL-6, and IL-10 in blister fluid of bullous pemphigoid. Arch Dermatol Res. 1996 Jun; 288(7):353-7.
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      122. Dummer W, Bastian BC, Ernst N, Schänzle C, Schwaaf A, Bröcker EB. Interleukin-10 production in malignant melanoma: preferential detection of IL-10-secreting tumor cells in metastatic lesions. Int J Cancer. 1996 May 29; 66(5):607-10.
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      123. Bastian BC, Harms D, Kreipe HH, Hamm H, Bröcker EB. [Giant cell fibroblastoma. A rare soft tissue tumor in childhood]. Hautarzt. 1996 Apr; 47(4):299-303.
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      124. Rank C, Bastian BC, Pistner H, Bröcker EB, Hamm H. [Microcystic adnexal carcinoma of the skin. An underestimated tumor]. Hautarzt. 1996 Apr; 47(4):284-8.
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      125. Bastian BC, Schacht RJ, Kämpgen E, Bröcker EB. Phospholipase A2 is secreted by murine keratinocytes after stimulation with IL-1 alpha and TNF-alpha. Arch Dermatol Res. 1996 Mar; 288(3):147-52.
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      126. Schmidt E, Ambach A, Bastian B, Bröcker EB, Zillikens D. Elevated levels of interleukin-8 in blister fluid of bullous pemphigoid compared with suction blisters of healthy control subjects. J Am Acad Dermatol. 1996 Feb; 34(2 Pt 1):310-2.
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      127. Dummer W, Blaheta HJ, Bastian BC, Schenk T, Bröcker EV, Remy W. Preoperative characterization of pigmented skin lesions by epiluminescence microscopy and high-frequency ultrasound. Arch Dermatol. 1995 Mar; 131(3):279-85.
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      128. Bastian BC, Nuss B, Römisch J, Kraus M, Bröcker EB. Autoantibodies to annexins: a diagnostic marker for cutaneous disorders? J Dermatol Sci. 1994 Dec; 8(3):194-202.
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      129. Drepper H, Köhler CO, Bastian B, Breuninger H, Bröcker EB, Göhl J, Groth W, Hermanek P, Hohenberger W, Kölmel K, et al. [Prognostic advantage for defined risk groups by lymphocyte dissection. Long-term study of 3,616 melanoma patients]. Hautarzt. 1994 Sep; 45(9):615-22.
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      130. Breuninger H, Köhler C, Drepper H, Bastian B, Bröcker EB, Göhl J, Groth W, Hermanek P, Hohenberger W, Lippold A, et al. [Is acrolentiginous melanoma (ALM) more malignant than superficially spreading melanoma (SSM) at a high-risk site? A matched-pair comparison between 113 ALM and SSM within the scope of a multicenter study]. Hautarzt. 1994 Aug; 45(8):529-31.
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      131. Bastian BC, Küchler A, Bröcker EB. [Benign giant cell tumor of the tendon sheath. A differential diagnosis of cutaneous tumors near the joint]. Hautarzt. 1994 Jun; 45(6):385-8.
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      132. Bastian BC, van der Piepen U, Römisch J, Pâques EP, Bröcker EB. Localization of annexins in normal and diseased human skin. J Dermatol Sci. 1993 Dec; 6(3):225-34.
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      133. Bastian BC, Sellert C, Seekamp A, Römisch J, Pâques EP, Bröcker EB. Inhibition of human skin phospholipase A2 by "lipocortins" is an indirect effect of substrate/lipocortin interaction. J Invest Dermatol. 1993 Sep; 101(3):359-63.
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      134. Drepper H, Köhler CO, Bastian B, Breuninger H, Bröcker EB, Göhl J, Groth W, Hermanek P, Hohenberger W, Lippold A, et al. Benefit of elective lymph node dissection in subgroups of melanoma patients. Results of a multicenter study of 3616 patients. Cancer. 1993 Aug 1; 72(3):741-9.
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