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    Jennifer Lai, MD

    TitleAssistant Professor
    SchoolUCSF School of Medicine
    Address513 Parnassus Ave, Med Sci
    San Francisco CA 94143
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      Collapse Biography 
      Collapse Education and Training
      Stanford UniversityB.S.2000
      Tufts University School of MedicineM.D./M.B.A.School of Medicine2005
      Columbia University Medical CenterInternship/ResidencyDepartment of Medicine2008
      UCSFAdvanced Training in Clinical Research2010
      UCSFFellowship in Gastroenterology2011
      UCSFFellowship in Advanced/Transplant Hepatology2012
      Collapse Awards and Honors
      American Society of Transplantation2016Clinical Science Career Development Award
      American Society of Transplantation2016 - 2017AST/Novartis Faculty Development Award (grant)
      American Geriatrics Society2015New Investigator Award
      International Liver Transplantation Society2015Young Investigator Award
      American Federation for Aging Research2014 - 2019Paul B. Beeson Scholar in Aging Research (grant)
      UCSF Pepper Center2014 - 2015Associate Scholar Genius Award (grant)
      UCSF Pepper Center2013 - 2014Pilot Award in Aging Research (grant)
      Association of Specialty Professors2013 - 2015T. Franklin Williams Scholar (grant)
      UCSF Liver Center2013 - 2014Pilot/Feasibility Award (grant)
      UCSF Resource Allocation Program2013 - 2014Pilot for Junior Investigator Award (grant)
      American College of Gastroenterology2012 - 2015Junior Faculty Career Development Award (grant)
      American College of Physicians2012 - currFellow
      American College of Gastrenterology2011 - 2012Clinical Research Award (grant)
      American Association for the Study of Liver Diseases2011 - 2012Transplant Hepatology Fellowship (grant)
      International Liver Transplantation Society2011Vanguard Award
      Northern California Kaiser Permanente2009 - 2010Sylvia Allison Kaplan Clinical Research Award (grant)
      Tufts University School of Medicine2005Alpha Omega Alpha

      Collapse Overview 
      Collapse Overview
      Dr. Lai is a general and transplant hepatologist who specializes in caring for patients with chronic viral hepatitis, autoimmune disorders, and cirrhosis, particularly those awaiting liver transplantation.

      Her academic mission is to improve the lives of patients with end-stage liver disease through the application of core principles of geriatrics into the care of patients with cirrhosis. Examples of these principles include assessing and reversing physical frailty, reducing polypharmacy, and integrating palliative care into liver transplantation. She is principal investigator of the NIH-funded Functional Assessment in Liver Transplantation (FrAILT) Study, which is actively enrolling patients with end-stage liver disease awaiting liver transplantation for assessments of physical frailty both before and after liver transplantation.

      After earning her undergraduate degree from Stanford University and combined MD/MBA degrees from Tufts University, she completed residency at the New York Presbyterian Hospital-Columbia and gastroenterology and advanced/transplant hepatology fellowships at UCSF. She is a member of the American Association for the Study of Liver Diseases, American Society of Transplantation, American Gastroenterological Association, American College of Gastroenterology, and International Liver Transplantation Society. She has been recognized as a Fellow of the American College of Physicians (FACP). She serves as Associate Editor for the American Journal of Transplantation, Transplantation,and is a member for the Editorial Board for Liver Transplantation.

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      Collapse In The News
      Collapse Faculty Mentoring
      Collapse Awarded Grants
      Collapse Clinical Trials

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Bajaj JS, O'Leary JG, Tandon P, Wong F, Garcia-Tsao G, Kamath PS, Maliakkal B, Biggins SW, Thuluvath P, Fallon MB, Subramanian RM, Vargas HE, Lai J, Thacker LR, Reddy KR. Hepatic Encephalopathy Remains an Important Independent Determinant of Mortality in Cirrhosis: A Multi-Center NACSELD Experience. Clin Gastroenterol Hepatol. 2016 Oct 5. PMID: 27720916.
        View in: PubMed
      2. Kathpalia P, Smith A, Lai JC. Underutilization of palliative care services in the liver transplant population. World J Transplant. 2016 Sep 24; 6(3):594-8. PMID: 27683638.
        View in: PubMed
      3. Lai JC, Volk ML, Strasburg D, Alexander N, et al. Performance-based measures associate with frailty in patients with end-stage liver disease. Transplantation. 2016 Aug 5. PMID: 27495749.
        View in: PubMed
      4. Law MF, Ho R, Cheung CK, Tam LH, Ma K, So KC, Ip B, So J, Lai J, Ng J, Tam TH. Prevention and management of hepatitis B virus reactivation in patients with hematological malignancies treated with anticancer therapy. World J Gastroenterol. 2016 Jul 28; 22(28):6484-500. PMID: 27605883; PMCID: PMC4968128.
      5. Wang CW, Feng S, Covinsky KE, Hayssen H, Zhou LQ, Yeh BM, Lai JC, et al. A Comparison of Muscle Function, Mass, and Quality in Liver Transplant Candidates: Results From the Functional Assessment in Liver Transplantation Study. Transplantation. 2016 Jun 1. PMID: 27314169.
        View in: PubMed
      6. Lai JC, Roberts JP. ABO-Nonidentical Liver Transplantation in the United States. Am J Transplant. 2016 Aug; 16(8):2430-6. PMID: 26932134.
        View in: PubMed
      7. Lai JC. Defining the threshold for too sick for transplant. Curr Opin Organ Transplant. 2016 Apr; 21(2):127-32. PMID: 26825359.
        View in: PubMed
      8. Lai JC, Dodge JL, Sen S, Covinsky K, Feng S. Functional decline in patients with cirrhosis awaiting liver transplantation: Results from the functional assessment in liver transplantation (FrAILT) study. Hepatology. 2016 Feb; 63(2):574-80. PMID: 26517301.
        View in: PubMed
      9. Wang CW, Covinsky KE, Feng S, Hayssen H, Segev DL, Lai JC. Functional impairment in older liver transplantation candidates: From the functional assessment in liver transplantation study. Liver Transpl. 2015 Dec; 21(12):1465-70. PMID: 26359787.
        View in: PubMed
      10. Kwong AJ, Lai JC, Dodge JL, Roberts JP. Outcomes for liver transplant candidates listed with low model for end-stage liver disease score. Liver Transpl. 2015 Nov; 21(11):1403-9. PMID: 26289624.
        View in: PubMed
      11. Saxena V, Lai JC. Kidney Failure and Liver Allocation: Current Practices and Potential Improvements. Adv Chronic Kidney Dis. 2015 Sep; 22(5):391-8. PMID: 26311601; PMCID: PMC4556134 [Available on 09/01/16].
      12. Volk ML, Goodrich N, Lai JC, Sonnenday C, Shedden K. Decision support for organ offers in liver transplantation. Liver Transpl. 2015 Jun; 21(6):784-91. PMID: 25779757.
        View in: PubMed
      13. Campos-Varela I, Lai JC, Verna EC, O'Leary JG, Todd Stravitz R, Forman LM, Trotter JF, Brown RS, Terrault NA. Hepatitis C genotype influences post-liver transplant outcomes. Transplantation. 2015 Apr; 99(4):835-40. PMID: 25211520.
        View in: PubMed
      14. Lai JC, Bikle DD, Lizaola B, Hayssen H, Terrault NA, Schwartz JB. Total 25(OH) vitamin D, free 25(OH) vitamin D and markers of bone turnover in cirrhotics with and without synthetic dysfunction. Liver Int. 2015 Oct; 35(10):2294-300. PMID: 25757956; PMCID: PMC4567539 [Available on 10/01/16].
      15. Lai JC, Covinsky KE, Hayssen H, Lizaola B, Dodge JL, Roberts JP, Terrault NA, Feng S. Clinician assessments of health status predict mortality in patients with end-stage liver disease awaiting liver transplantation. Liver Int. 2015 Sep; 35(9):2167-73. PMID: 25644788; PMCID: PMC4517979 [Available on 09/01/16].
      16. Lai JC, Shoback DM, Zipperstein J, Lizaola B, Tseng S, Terrault NA. Bone Mineral Density, Bone Turnover, and Systemic Inflammation in Non-cirrhotics with Chronic Hepatitis C. Dig Dis Sci. 2015 Jun; 60(6):1813-9. PMID: 25563723.
        View in: PubMed
      17. Bissell DM, Lai JC, Meister RK, Blanc PD. Role of delta-aminolevulinic acid in the symptoms of acute porphyria. Am J Med. 2015 Mar; 128(3):313-7. PMID: 25446301; PMCID: PMC4339446 [Available on 03/01/16].
      18. Sharpton SR, Feng S, Hameed B, Yao F, Lai JC. Combined effects of recipient age and model for end-stage liver disease score on liver transplantation outcomes. Transplantation. 2014 Sep 15; 98(5):557-62. PMID: 24717221; PMCID: PMC4461209.
      19. Lai JC, Covinsky K, Feng S. The octogenarian donor: can the liver be "younger than stated age"? Am J Transplant. 2014 Sep; 14(9):1962-3. PMID: 25307032; PMCID: PMC4383764.
      20. Feng S, Lai JC. Expanded criteria donors. Clin Liver Dis. 2014 Aug; 18(3):633-49. PMID: 25017080.
        View in: PubMed
      21. Lai JC, Feng S, Terrault NA, Lizaola B, Hayssen H, Covinsky K. Frailty predicts waitlist mortality in liver transplant candidates. Am J Transplant. 2014 Aug; 14(8):1870-9. PMID: 24935609; PMCID: PMC4107151.
      22. Schwartz JB, Lai J, Lizaola B, Kane L, Markova S, Weyland P, Terrault NA, Stotland N, Bikle D. A comparison of measured and calculated free 25(OH) vitamin D levels in clinical populations. J Clin Endocrinol Metab. 2014 May; 99(5):1631-7. PMID: 24483159; PMCID: PMC4010704.
      23. Schwartz JB, Lai J, Lizaola B, Kane L, Weyland P, Terrault NA, Stotland N, Bikle D. Variability in free 25(OH) vitamin D levels in clinical populations. J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A:156-8. PMID: 24240067; PMCID: PMC4022715.
      24. Lai JC, Kahn JG, Tavakol M, Peters MG, Roberts JP. Reducing infection transmission in solid organ transplantation through donor nucleic acid testing: a cost-effectiveness analysis. Am J Transplant. 2013 Oct; 13(10):2611-8. PMID: 24034208; PMCID: PMC4091990.
      25. Lai JC, Feng S, Vittinghoff E, Roberts JP. Offer patterns of nationally placed livers by donation service area. Liver Transpl. 2013 Apr; 19(4):404-10. PMID: 23447450; PMCID: PMC3689315.
      26. Halldorson JB, Paarsch HJ, Dodge JL, Segre AM, Lai J, Roberts JP. Center competition and outcomes following liver transplantation. Liver Transpl. 2013 Jan; 19(1):96-104. PMID: 23086897; PMCID: PMC4141491.
      27. Lai JC, Feng S, Roberts JP. An examination of liver offers to candidates on the liver transplant wait-list. Gastroenterology. 2012 Nov; 143(5):1261-5. PMID: 22841780; PMCID: PMC3480537.
      28. Lai JC, O'Leary JG, Trotter JF, Verna EC, Brown RS, Stravitz RT, Duman JD, Forman LM, Terrault NA. Risk of advanced fibrosis with grafts from hepatitis C antibody-positive donors: a multicenter cohort study. Liver Transpl. 2012 May; 18(5):532-8. PMID: 22271671; PMCID: PMC3334393.
      29. Saxena V, Lai JC, O'Leary JG, Verna EC, Brown RS, Stravitz RT, Trotter JF, Krishnan K, Terrault NA. Recipient-donor race mismatch for African American liver transplant patients with chronic hepatitis C. Liver Transpl. 2012 May; 18(5):524-31. PMID: 22140019; PMCID: PMC3314141.
      30. Verna EC, Valadao R, Farrand E, Pichardo EM, Lai JC, Terrault NA, Brown RS. Effects of ethnicity and socioeconomic status on survival and severity of fibrosis in liver transplant recipients with hepatitis C virus. Liver Transpl. 2012 Apr; 18(4):461-7. PMID: 22467547; PMCID: PMC3674870.
      31. Lai JC, Roberts JP, Vittinghoff E, Terrault NA, Feng S. Patient, center and geographic characteristics of nationally placed livers. Am J Transplant. 2012 Apr; 12(4):947-53. PMID: 22300591; PMCID: PMC3689311.
      32. Brandman D, Pingitore A, Lai JC, Roberts JP, Ferrell L, Bass NM, Terrault NA. Hepatic steatosis at 1 year is an additional predictor of subsequent fibrosis severity in liver transplant recipients with recurrent hepatitis C virus. Liver Transpl. 2011 Dec; 17(12):1380-6. PMID: 21770018; PMCID: PMC3712627.
      33. Lai JC, Verna EC, Brown RS, O'Leary JG, Trotter JF, Forman LM, Duman JD, Foster RG, Stravitz RT, Terrault NA. Hepatitis C virus-infected women have a higher risk of advanced fibrosis and graft loss after liver transplantation than men. Hepatology. 2011 Aug; 54(2):418-24. PMID: 21538434; PMCID: PMC3144983.
      34. Lai JC, Feng S, Roberts JP, Terrault NA. Gender differences in liver donor quality are predictive of graft loss. Am J Transplant. 2011 Feb; 11(2):296-302. PMID: 21219572; PMCID: PMC3076602.
      35. Lai JC, Terrault NA, Vittinghoff E, Biggins SW. Height contributes to the gender difference in wait-list mortality under the MELD-based liver allocation system. Am J Transplant. 2010 Dec; 10(12):2658-64. PMID: 21087414; PMCID: PMC3059496.
      36. Monto A, Schooley RT, Lai JC, Sulkowski MS, Chung RT, Pawlotsky JM, McHutchison JG, Jacobson IM. Lessons from HIV therapy applied to viral hepatitis therapy: summary of a workshop. Am J Gastroenterol. 2010 May; 105(5):989-1004; quiz 988, 1005. PMID: 20087331.
        View in: PubMed
      37. Lai JC, Montero A, Lebwohl B, Brown RS. A novel housestaff educational model for quaternary-care patients at an academic health center. Acad Med. 2009 Feb; 84(2):206-11. PMID: 19174667.
        View in: PubMed
      38. Lai JC, Pichardo EM, Emond JC, Brown RS. Resource utilization of living donor versus deceased donor liver transplantation is similar at an experienced transplant center. Am J Transplant. 2009 Mar; 9(3):586-91. PMID: 19191773.
        View in: PubMed
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