Michael Evans, PhD
|School||UCSF School of Medicine|
|Address||185 Berry St B N|
San Francisco CA 94107
|Saint Mary's College of Maryland||BA||2001||Chemistry|
|The Scripps Research Institute||PhD||2007||Chemistry|
|Memorial Sloan Kettering Cancer Center||Postdoctoral||2013||Human Oncology and Pathogenesis Program|
|UCSF Academic Senate||2016
||2017||Team Science Award|
||2017||Brain Tumor SPORE Developmental Research Project|
||2017||Program in Cancer Imaging and Therapy Pilot Award|
|DOD Prostate Cancer Research Program||2015
||2017||Idea Development Award|
|UCSF Academic Senate||2014
|Prostate Cancer Foundation||2013
||2016||David H. Koch Young Investigator Award|
|National Cancer Institute||2012
||2017||Pathway to Independence Award|
|Imaging and Radiation Sciences Brigde Program, MSKCC||2012
|Imaging and Radiation Sciences Bridge Program, Memorial Sloan Kettering Cancer Center||2011||Research Award|
|Brain Tumor Center of Memorial Sloan Kettering Cancer Center||2011||Research Award|
|National Institutes of Health and Memorial Sloan Kettering Cancer Center||2007
Michael Evans, PhD, is an Assistant Professor in Residence in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. He is an experienced chemical biologist with a focus on molecular imaging and organic chemistry. Dr. Evans earned a BA in Chemistry from St. Mary’s College, Maryland and he obtained his PhD in Organic Chemistry from The Scripps Research Institute in La Jolla, California under the supervision of Professor Benjamin Cravatt, followed by postdoctoral fellowship in Molecular Imaging from the Memorial Sloan Kettering Cancer Center in New York under the supervision of Professors Charles Sawyers and Jason Lewis. In October 2013, Dr. Evans accepted the Assistant Professor in Residence position at UCSF.
Dr. Evans specializes in small molecule synthesis, proteomics, and preclinical development and translation of new radiotracers. By combining his expertise in chemical biology and molecular imaging, Dr. Evans and his group seek to discover and exploit for imaging biomarkers directly regulated by central oncogenes. By approaching molecular imaging as a chemical biologist, Dr. Evans aims to create a repertoire of biomarkers that can be applied to define which oncogenes are active in a given tumor, as well as interpret the extent to which the activity of the oncogene is suppressed by a therapeutic intervention. To date, he has developed biomarkers measuring the activity of the androgen receptor and MYC in prostate cancer, and his group is now actively developing new imaging biomarkers to other important oncogenes.
Dr. Evans is a member of the American Chemical Society, the American Association for Cancer Research, the Society of Nuclear Medicine and Molecular Imaging, and the World Molecular Imaging Society. He has been invited nationally and internationally to lecture about his research. Dr. Evans has published over 25 peer-reviewed articles, 10 abstracts, and is a co-inventor on 3 patents. Dr. Evans also is the principle investigator or co-investigator on four human trials focused on new strategies for imaging solid tumors. Dr. Evans serves on the scientific advisory board of ORIC Pharmaceuticals, Inc.
Cancer Biology, Molecular Imaging, and Organic Chemistry
Small molecule synthesis, proteomics, preclinical development of radiotracers, translation of human ready radiotracers, bioconjugation chemistry.
Cancer, molecular imaging of oncogene signaling with positron emission tomography, biomarkers, proteomics, organic chemistry, chemical biology, antibody development, prostate, brain, breast, oncogenes, androgen receptor, MYC, PI3K, tumor suppressors, signaling pathways, serum biomarkers, nuclear medicine
Education and Training:
• Bachelor of Art: St. Mary’s College, St. Mary’s City, Maryland - Chemistry
• Doctor of Philosophy: The Scripps Research Institute, La Jolla, California - Organic Chemistry
• Postdoctoral Fellowship: Memorial Sloan Kettering Cancer Center, New York - Molecular Imaging
, molecular imaging
, positron emission tomography
, organic chemistry
, chemical biology
, androgen receptor
, tumor suppressors
, signaling pathways
, serum biomarkers
, nuclear medicine.
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