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Nirav Bhakta, MD

TitleAssistant Professor
SchoolUCSF School of Medicine
DepartmentMedicine
Address513 Parnassus Ave
San Francisco CA 94143
Phone415-476-4176
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoFellowship2011Pulmonary and Critical Care Medicine
    University of California, San FranciscoResidency 2008School of Medicine - Internal Medicine
    Stanford UniversityM.D.2006School of Medicine
    Stanford UniversityPh.D.2006School of Medicine, Molecular and Cellular Physiology
    Massachusetts Institute of TechnologyElectrical Engineering and Electrical Science1998Electrical Engineering

    Collapse Research 
    Collapse Research Activities and Funding
    Translational research on the role of IL-17 cytokines in severe asthma
    NIH/NHLBI K23HL116657May 1, 2014 - Apr 30, 2019
    Role: Principal Investigator
    Using signatures of T-helper cell inflammation to phenotype human asthma
    NIH/NHLBI F32HL110720Jan 1, 2012 - Dec 31, 2012
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Bhakta NR. Pitfalls of probiotics. Sci Transl Med. 2016 Dec 07; 8(368):368ec194. PMID: 27928020.
      View in: PubMed
    2. Durack J, Lynch SV, Nariya S, Bhakta NR, Beigelman A, Castro M, Dyer AM, Israel E, Kraft M, Martin RJ, Mauger DT, Rosenberg SR, Sharp-King T, White SR, Woodruff PG, Avila PC, Denlinger LC, Holguin F, Lazarus SC, Lugogo N, Moore WC, Peters SP, Que L, Smith LJ, Sorkness CA, Wechsler M, Wenzel SE, Boushey HA, Huang YJ. Features of the bronchial bacterial microbiome associated with atopy, asthma and responsiveness to inhaled corticosteroid treatment. J Allergy Clin Immunol. 2016 Nov 9. PMID: 27838347.
      View in: PubMed
    3. Denlinger LC, Phillips BR, Ramratnam S, Ross K, Bhakta N, Cardet JC, Castro M, Peters SP, Phipatanakul W, Aujla S, Bacharier LB, Bleecker ER, Comhair SA, Coverstone A, DeBoer M, Erzurum SC, Fain SB, Fajt M, Fitzpatrick AM, Gaffin J, Gaston B, Hastie AT, Hawkins GA, Holguin F, Irani AM, Israel E, Levy BD, Ly N, Meyers DA, Moore WC, Myers R, Opina MT, Peters MC, Schiebler ML, Sorkness RL, Teague WG, Wenzel SE, Woodruff PG, Mauger DT, Fahy JV, Jarjour NN, et al. Inflammatory and Co-Morbid Features of Patients with Severe Asthma and Frequent Exacerbations. Am J Respir Crit Care Med. 2016 Aug 24. PMID: 27556234.
      View in: PubMed
    4. Ramstein J, Broos CE, Simpson LJ, Ansel KM, Sun SA, Ho ME, Woodruff PG, Bhakta N, Christian L, Nguyen CP, Antalek BJ, Benn BS, Hendriks RW, van den Blink B, Kool M, Koth LL. IFN-?-Producing T-Helper 17.1 Cells Are Increased in Sarcoidosis and Are More Prevalent than T-Helper Type 1 Cells. Am J Respir Crit Care Med. 2016 Jun 1; 193(11):1281-91. PMID: 26649486.
      View in: PubMed
    5. Hoffman SM, Chapman DG, Lahue KG, Cahoon JM, Rattu GK, Daphtary N, Aliyeva M, Fortner KA, Erzurum SC, Comhair SA, Woodruff PG, Bhakta N, Dixon AE, Irvin CG, Janssen-Heininger YM, Poynter ME, Anathy V. Protein disulfide isomerase-endoplasmic reticulum resident protein 57 regulates allergen-induced airways inflammation, fibrosis, and hyperresponsiveness. J Allergy Clin Immunol. 2016 Mar; 137(3):822-832.e7. PMID: 26435004.
      View in: PubMed
    6. Lawson DA, Bhakta NR, Kessenbrock K, Prummel KD, Yu Y, Takai K, Zhou A, Eyob H, Balakrishnan S, Wang CY, Yaswen P, Goga A, Werb Z. Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells. Nature. 2015 Oct 1; 526(7571):131-5. PMID: 26416748.
      View in: PubMed
    7. Simpson LJ, Patel S, Bhakta NR, Choy DF, Brightbill HD, Ren X, Wang Y, Pua HH, Baumjohann D, Montoya MM, Panduro M, Remedios KA, Huang X, Fahy JV, Arron JR, Woodruff PG, Ansel KM. A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production. Nat Immunol. 2014 Dec; 15(12):1162-70. PMID: 25362490; PMCID: PMC4233009.
    8. Bhakta NR, Erle DJ. IL-17 and "TH2-high" asthma: Adding fuel to the fire? J Allergy Clin Immunol. 2014 Nov; 134(5):1187-8. PMID: 25174869.
      View in: PubMed
    9. Su R, Li MM, Bhakta NR, Solberg OD, Darnell EP, Ramstein J, Garudadri S, Ho M, Woodruff PG, Koth LL. Longitudinal analysis of sarcoidosis blood transcriptomic signatures and disease outcomes. Eur Respir J. 2014 Oct; 44(4):985-93. PMID: 25142485.
      View in: PubMed
    10. Greer AM, Matthay MA, Kukreja J, Bhakta NR, Nguyen CP, Wolters PJ, Woodruff PG, Fahy JV, Shin JS. Accumulation of BDCA1? dendritic cells in interstitial fibrotic lung diseases and Th2-high asthma. PLoS One. 2014; 9(6):e99084. PMID: 24915147; PMCID: PMC4051692.
    11. Peters MC, Mekonnen ZK, Yuan S, Bhakta NR, Woodruff PG, Fahy JV. Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma. J Allergy Clin Immunol. 2014 Feb; 133(2):388-94. PMID: 24075231; PMCID: PMC3981552.
    12. Bhakta NR, Solberg OD, Nguyen CP, Nguyen CN, Arron JR, Fahy JV, Woodruff PG. A qPCR-based metric of Th2 airway inflammation in asthma. Clin Transl Allergy. 2013; 3(1):24. PMID: 23866775; PMCID: PMC3724712.
    13. Levänen B, Bhakta NR, Torregrosa Paredes P, Barbeau R, Hiltbrunner S, Pollack JL, Sköld CM, Svartengren M, Grunewald J, Gabrielsson S, Eklund A, Larsson BM, Woodruff PG, Erle DJ, Wheelock ÅM. Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients. J Allergy Clin Immunol. 2013 Mar; 131(3):894-903. PMID: 23333113; PMCID: PMC4013392.
    14. Solberg OD, Ostrin EJ, Love MI, Peng JC, Bhakta NR, Hou L, Nguyen C, Solon M, Nguyen C, Barczak AJ, Zlock LT, Blagev DP, Finkbeiner WE, Ansel KM, Arron JR, Erle DJ, Woodruff PG. Airway epithelial miRNA expression is altered in asthma. Am J Respir Crit Care Med. 2012 Nov 15; 186(10):965-74. PMID: 22955319; PMCID: PMC3530212.
    15. Koth LL, Solberg OD, Peng JC, Bhakta NR, Nguyen CP, Woodruff PG. Sarcoidosis blood transcriptome reflects lung inflammation and overlaps with tuberculosis. Am J Respir Crit Care Med. 2011 Nov 15; 184(10):1153-63. PMID: 21852540; PMCID: PMC3262024.
    16. Bhakta NR, Woodruff PG. Human asthma phenotypes: from the clinic, to cytokines, and back again. Immunol Rev. 2011 Jul; 242(1):220-32. PMID: 21682748; PMCID: PMC3391010.
    17. Bhakta NR, Lewis RS. Real-time measurement of signaling and motility during T cell development in the thymus. Semin Immunol. 2005 Dec; 17(6):411-20. PMID: 16256363.
      View in: PubMed
    18. Bhakta NR, Oh DY, Lewis RS. Calcium oscillations regulate thymocyte motility during positive selection in the three-dimensional thymic environment. Nat Immunol. 2005 Feb; 6(2):143-51. PMID: 15654342.
      View in: PubMed
    19. Bousso P, Bhakta NR, Lewis RS, Robey E. Dynamics of thymocyte-stromal cell interactions visualized by two-photon microscopy. Science. 2002 Jun 7; 296(5574):1876-80. PMID: 12052962.
      View in: PubMed
    20. Bonassar LJ, Grodzinsky AJ, Frank EH, Davila SG, Bhaktav NR, Trippel SB. The effect of dynamic compression on the response of articular cartilage to insulin-like growth factor-I. J Orthop Res. 2001 Jan; 19(1):11-7. PMID: 11332605.
      View in: PubMed
    21. Bhakta NR, Garcia AM, Frank EH, Grodzinsky AJ, Morales TI. The insulin-like growth factors (IGFs) I and II bind to articular cartilage via the IGF-binding proteins. J Biol Chem. 2000 Feb 25; 275(8):5860-6. PMID: 10681577.
      View in: PubMed
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