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The human ciliopathy protein RSG1 links the CPLANE complex to transition zone architecture. bioRxiv. 2024 Sep 26.
Vazquez N, Lee C, Valenzuela I, Phan TP, Derderian C, Chávez M, Mooney NA, Demeter J, Aziz-Zanjani MO, Cusco I, Codina M, Martínez-Gil N, Valverde D, Solarat C, Buel AL, Thauvin-Robinet C, Steichen E, Filges I, Joset P, De Geyter J, Vaidyanathan K, Gardner T, Toriyama M, Marcotte EM, Roberson EC, Jackson PK, Reiter JF, Tizzano EF, Wallingford JB. PMID: 39386566; PMCID: PMC11463498.
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PubMed Mentions:
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Variants in tubule epithelial regulatory elements mediate most heritable differences in human kidney function. Nat Genet. 2024 Sep 10.
Loeb GB, Kathail P, Shuai RW, Chung R, Grona RJ, Peddada S, Sevim V, Federman S, Mader K, Chu AY, Davitte J, Du J, Gupta AR, Ye CJ, Shafer S, Przybyla L, Rapiteanu R, Ioannidis NM, Reiter JF. PMID: 39256582.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Cilia-enriched oxysterol 7β,27-DHC is required for polycystin ion channel activation. Nat Commun. 2024 Jul 31; 15(1):6468.
Ha K, Mundt-Machado N, Bisignano P, Pinedo A, Raleigh DR, Loeb G, Reiter JF, Cao E, Delling M. PMID: 39085216; PMCID: PMC11291729.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Variants in tubule epithelial regulatory elements mediate most heritable differences in human kidney function. bioRxiv. 2024 Jun 22.
Loeb GB, Kathail P, Shuai R, Chung R, Grona RJ, Peddada S, Sevim V, Federman S, Mader K, Chu A, Davitte J, Du J, Gupta AR, Ye CJ, Shafer S, Przybyla L, Rapiteanu R, Ioannidis N, Reiter JF. PMID: 38948875; PMCID: PMC11212968.
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PubMed Mentions:
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An alternative cell cycle coordinates multiciliated cell differentiation. Nature. 2024 Jun; 630(8015):214-221.
Choksi SP, Byrnes LE, Konjikusic MJ, Tsai BWH, Deleon R, Lu Q, Westlake CJ, Reiter JF. PMID: 38811726.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Rab35 Is Required for Embryonic Development and Kidney and Ureter Homeostasis through Regulation of Epithelial Cell Junctions. J Am Soc Nephrol. 2024 Jun 01; 35(6):719-732.
Clearman KR, Timpratoom N, Patel D, Rains AB, Haycraft CJ, Croyle MJ, Reiter JF, Yoder BK. PMID: 38530365; PMCID: PMC11164122.
View in:
PubMed Mentions: Fields:
Translation:
AnimalsCells
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Emerging mechanistic understanding of cilia function in cellular signalling. Nat Rev Mol Cell Biol. 2024 Jul; 25(7):555-573.
Hilgendorf KI, Myers BR, Reiter JF. PMID: 38366037; PMCID: PMC11199107.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. Nat Struct Mol Biol. 2024 Apr; 31(4):667-677.
Hoppe N, Harrison S, Hwang SH, Chen Z, Karelina M, Deshpande I, Suomivuori CM, Palicharla VR, Berry SP, Tschaikner P, Regele D, Covey DF, Stefan E, Marks DS, Reiter JF, Dror RO, Evers AS, Mukhopadhyay S, Manglik A. PMID: 38326651; PMCID: PMC11221913.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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ADPKD-Causing Missense Variants in Polycystin-1 Disrupt Cell Surface Localization or Polycystin Channel Function. bioRxiv. 2023 Dec 07.
Ha K, Loeb GB, Park M, Pinedo A, Park CH, Brandes N, Ritu F, Ye CJ, Reiter JF, Delling M. PMID: 38106161; PMCID: PMC10723288.
View in:
PubMed Mentions:
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Primary cilia control oligodendrocyte precursor cell proliferation in white matter injury via Hedgehog-independent CREB signaling. Cell Rep. 2023 10 31; 42(10):113272.
Hoi KK, Xia W, Wei MM, Ulloa Navas MJ, Garcia Verdugo JM, Nachury MV, Reiter JF, Fancy SPJ. PMID: 37858465; PMCID: PMC10715572.
View in:
PubMed Mentions: Fields:
Translation:
Cells
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Polycystin-2-dependent transcriptome reveals early response of autosomal dominant polycystic kidney disease. Physiol Genomics. 2023 Nov 01; 55(11):565-577.
Jung HJ, Dixon EE, Coleman R, Watnick T, Reiter JF, Outeda P, Cebotaru V, Woodward OM, Welling PA. PMID: 37720991; PMCID: PMC11178268.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Rab35 is required for embryonic development and kidney and ureter homeostasis through regulation of epithelial cell junctions. bioRxiv. 2023 Sep 12.
Clearman KR, Timpratoom N, Patel D, Rains AB, Haycraft CJ, Croyle MJ, Reiter JF, Yoder BK. PMID: 37745459; PMCID: PMC10515836.
View in:
PubMed Mentions:
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An RFX transcription factor regulates ciliogenesis in the closest living relatives of animals. Curr Biol. 2023 09 11; 33(17):3747-3758.e9.
Coyle MC, Tajima AM, Leon F, Choksi SP, Yang A, Espinoza S, Hughes TR, Reiter JF, Booth DS, King N. PMID: 37552984; PMCID: PMC10530576.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Hedgehog target genes regulate lipid metabolism to drive basal cell carcinoma and medulloblastoma. Res Sq. 2023 Aug 03.
Daggubati V, Vykunta A, Choudhury A, Qadeer Z, Mirchia K, Saulnier O, Zakimi N, Hines K, Paul M, Wang L, Jura N, Xu L, Reiter J, Taylor M, Weiss W, Raleigh D. PMID: 37577529; PMCID: PMC10418546.
View in:
PubMed Mentions:
1
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Seriously cilia: A tiny organelle illuminates evolution, disease, and intercellular communication. Dev Cell. 2023 08 07; 58(15):1333-1349.
Derderian C, Canales GI, Reiter JF. PMID: 37490910; PMCID: PMC10880727.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. bioRxiv. 2023 May 24.
Hoppe N, Harrison S, Hwang SH, Chen Z, Karelina M, Deshpande I, Suomivuori CM, Palicharla VR, Berry SP, Tschaikner P, Regele D, Covey DF, Stefan E, Marks DS, Reiter J, Dror RO, Evers AS, Mukhopadhyay S, Manglik A. PMID: 37292845; PMCID: PMC10245861.
View in:
PubMed Mentions:
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Physiological Condition-Dependent Changes in Ciliary GPCR Localization in the Brain. eNeuro. 2023 03; 10(3).
Brewer KM, Engle SE, Bansal R, Brewer KK, Jasso KR, McIntyre JC, Vaisse C, Reiter JF, Berbari NF. PMID: 36849261; PMCID: PMC10012409.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis. Elife. 2023 02 15; 12.
Hall EA, Kumar D, Prosser SL, Yeyati PL, Herranz-Pérez V, García-Verdugo JM, Rose L, McKie L, Dodd DO, Tennant PA, Megaw R, Murphy LC, Ferreira MF, Grimes G, Williams L, Quidwai T, Pelletier L, Reiter JF, Mill P. PMID: 36790165; PMCID: PMC9998092.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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MRAP2 regulates energy homeostasis by promoting primary cilia localization of MC4R. JCI Insight. 2023 01 24; 8(2).
Bernard A, Ojeda Naharros I, Yue X, Mifsud F, Blake A, Bourgain-Guglielmetti F, Ciprin J, Zhang S, McDaid E, Kim K, Nachury MV, Reiter JF, Vaisse C. PMID: 36692018; PMCID: PMC9977312.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Zika virus alters centrosome organization to suppress the innate immune response. EMBO Rep. 2022 09 05; 23(9):e52211.
Kodani A, Knopp KA, Di Lullo E, Retallack H, Kriegstein AR, DeRisi JL, Reiter JF. PMID: 35793002; PMCID: PMC9442309.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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A kinesin mimics DNA. Nat Cell Biol. 2022 07; 24(7):1015-1016.
Kumar D, Reiter JF. PMID: 35798844.
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PubMed Mentions: Fields:
Translation:
Cells
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The Intimate Connection Between Lipids and Hedgehog Signaling. Front Cell Dev Biol. 2022; 10:876815.
Nguyen TD, Truong ME, Reiter JF. PMID: 35757007; PMCID: PMC9222137.
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PubMed Mentions:
6
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The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans. Science. 2022 05 13; 376(6594):eabl4896.
Tabula Sapiens Consortium*, Jones RC, Karkanias J, Krasnow MA, Pisco AO, Quake SR, Salzman J, Yosef N, Bulthaup B, Brown P, Harper W, Hemenez M, Ponnusamy R, Salehi A, Sanagavarapu BA, Spallino E, Aaron KA, Concepcion W, Gardner JM, Kelly B, Neidlinger N, Wang Z, Crasta S, Kolluru S, Morri M, Tan SY, Travaglini KJ, Xu C, Alcántara-Hernández M, Almanzar N, Antony J, Beyersdorf B, Burhan D, Calcuttawala K, Carter MM, Chan CKF, Chang CA, Chang S, Colville A, Culver RN, Cvijovic I, D'Amato G, Ezran C, Galdos FX, Gillich A, Goodyer WR, Hang Y, Hayashi A, Houshdaran S, Huang X, Irwin JC, Jang S, Juanico JV, Kershner AM, Kim S, Kiss B, Kong W, Kumar ME, Kuo AH, Li B, Loeb GB, Lu WJ, Mantri S, Markovic M, McAlpine PL, de Morree A, Mrouj K, Mukherjee S, Muser T, Neuhöfer P, Nguyen TD, Perez K, Puluca N, Qi Z, Rao P, Raquer-McKay H, Schaum N, Scott B, Seddighzadeh B, Segal J, Sen S, Sikandar S, Spencer SP, Steffes LC, Subramaniam VR, Swarup A, Swift M, Van Treuren W, Trimm E, Veizades S, Vijayakumar S, Vo KC, Vorperian SK, Wang W, Weinstein HNW, Winkler J, Wu TTH, Xie J, Yung AR, Zhang Y, Detweiler AM, Mekonen H, Neff NF, Sit RV, Tan M, Yan J, Bean GR, Charu V, Forgó E, Martin BA, Ozawa MG, Silva O, Toland A, Vemuri VNP, Afik S, Awayan K, Botvinnik OB, Byrne A, Chen M, Dehghannasiri R, Gayoso A, Granados AA, Li Q, Mahmoudabadi G, McGeever A, Olivieri JE, Park M, Ravikumar N, Stanley G, Tan W, Tarashansky AJ, Vanheusden R, Wang P, Wang S, Xing G, Dethlefsen L, Ezran C, Gillich A, Hang Y, Ho PY, Irwin JC, Jang S, Leylek R, Liu S, Maltzman JS, Metzger RJ, Phansalkar R, Sasagawa K, Sinha R, Song H, Swarup A, Trimm E, Veizades S, Wang B, Beachy PA, Clarke MF, Giudice LC, Huang FW, Huang KC, Idoyaga J, Kim SK, Kuo CS, Nguyen P, Rando TA, Red-Horse K, Reiter J, Relman DA, Sonnenburg JL, Wu A, Wu SM, Wyss-Coray T. PMID: 35549404; PMCID: PMC9812260.
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PubMed Mentions:
303 Fields:
Translation:
HumansCells
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Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity. Dev Cell. 2021 12 20; 56(24):3334-3348.e6.
Xie C, Abrams SR, Herranz-Pérez V, García-Verdugo JM, Reiter JF. PMID: 34932949; PMCID: PMC8797031.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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ATXN10 Is Required for Embryonic Heart Development and Maintenance of Epithelial Cell Phenotypes in the Adult Kidney and Pancreas. Front Cell Dev Biol. 2021; 9:705182.
Bentley-Ford MR, Andersen RS, Croyle MJ, Haycraft CJ, Clearman KR, Foote JB, Reiter JF, Yoder BK. PMID: 34970537; PMCID: PMC8712648.
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PubMed Mentions:
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Ciliary Hedgehog signaling patterns the digestive system to generate mechanical forces driving elongation. Nat Commun. 2021 12 10; 12(1):7186.
Yang Y, Paivinen P, Xie C, Krup AL, Makela TP, Mostov KE, Reiter JF. PMID: 34893605; PMCID: PMC8664829.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Ciliary Hedgehog signaling regulates cell survival to build the facial midline. Elife. 2021 10 21; 10.
Abrams SR, Reiter JF. PMID: 34672258; PMCID: PMC8592574.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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A ciliopathy complex builds distal appendages to initiate ciliogenesis. J Cell Biol. 2021 09 06; 220(9).
Kumar D, Rains A, Herranz-Pérez V, Lu Q, Shi X, Swaney DL, Stevenson E, Krogan NJ, Huang B, Westlake C, Garcia-Verdugo JM, Yoder BK, Reiter JF. PMID: 34241634; PMCID: PMC8276316.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Label-retention expansion microscopy. J Cell Biol. 2021 09 06; 220(9).
Shi X, Li Q, Dai Z, Tran AA, Feng S, Ramirez AD, Lin Z, Wang X, Chow TT, Chen J, Kumar D, McColloch AR, Reiter JF, Huang EJ, Seiple IB, Huang B. PMID: 34228783; PMCID: PMC8266563.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
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Melanocortin 4 receptor signals at the neuronal primary cilium to control food intake and body weight. J Clin Invest. 2021 05 03; 131(9).
Wang Y, Bernard A, Comblain F, Yue X, Paillart C, Zhang S, Reiter JF, Vaisse C. PMID: 33938449; PMCID: PMC8087202.
View in:
PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Vertebrate cells differentially interpret ciliary and extraciliary cAMP. Cell. 2021 05 27; 184(11):2911-2926.e18.
Truong ME, Bilekova S, Choksi SP, Li W, Bugaj LJ, Xu K, Reiter JF. PMID: 33932338; PMCID: PMC8450001.
View in:
PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
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Smoothened-activating lipids drive resistance to CDK4/6 inhibition in Hedgehog-associated medulloblastoma cells and preclinical models. J Clin Invest. 2021 03 15; 131(6).
Daggubati V, Hochstelter J, Bommireddy A, Choudhury A, Krup AL, Kaur P, Tong P, Li A, Xu L, Reiter JF, Raleigh DR. PMID: 33476305; PMCID: PMC7954583.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway. J Cell Biol. 2021 01 04; 220(1).
Findakly S, Daggubati V, Garcia G, LaStella SA, Choudhury A, Tran C, Li A, Tong P, Garcia JQ, Puri N, Reiter JF, Xu L, Raleigh DR. PMID: 33284321; PMCID: PMC7721912.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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How the centriole builds its cilium: of mothers, daughters, and the acquisition of appendages. Curr Opin Struct Biol. 2021 02; 66:41-48.
Kumar D, Reiter J. PMID: 33160100.
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PubMed Mentions:
32 Fields:
Translation:
HumansCells
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A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development. Elife. 2020 08 25; 9.
Hasenpusch-Theil K, Laclef C, Colligan M, Fitzgerald E, Howe K, Carroll E, Abrams SR, Reiter JF, Schneider-Maunoury S, Theil T. PMID: 32840212; PMCID: PMC7481005.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis. Cell. 2019 11 27; 179(6):1289-1305.e21.
Hilgendorf KI, Johnson CT, Mezger A, Rice SL, Norris AM, Demeter J, Greenleaf WJ, Reiter JF, Kopinke D, Jackson PK. PMID: 31761534; PMCID: PMC7332222.
View in:
PubMed Mentions:
102 Fields:
Translation:
AnimalsCells
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Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision. Cell. 2019 06 27; 178(1):261.
Phua SC, Chiba S, Suzuki M, Su E, Roberson EC, Pusapati GV, Schurmans S, Setou M, Rohatgi R, Reiter JF, Ikegami K, Inoue T. PMID: 31251914.
View in:
PubMed Mentions:
6 Fields:
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SFI1 promotes centriole duplication by recruiting USP9X to stabilize the microcephaly protein STIL. J Cell Biol. 2019 07 01; 218(7):2185-2197.
Kodani A, Moyer T, Chen A, Holland A, Walsh CA, Reiter JF. PMID: 31197030; PMCID: PMC6605807.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Hedgehog Pathway Activation Alters Ciliary Signaling in Primary Hypothalamic Cultures. Front Cell Neurosci. 2019; 13:266.
Bansal R, Engle SE, Antonellis PJ, Whitehouse LS, Baucum AJ, Cummins TR, Reiter JF, Berbari NF. PMID: 31249512; PMCID: PMC6582312.
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PubMed Mentions:
8
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Deformed alignment of super-resolution images for semi-flexible structures. PLoS One. 2019; 14(3):e0212735.
Shi X, Garcia G, Wang Y, Reiter JF, Huang B. PMID: 30865666; PMCID: PMC6415779.
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PubMed Mentions:
6 Fields:
-
Misactivation of Hedgehog signaling causes inherited and sporadic cancers. J Clin Invest. 2019 02 01; 129(2):465-475.
Raleigh DR, Reiter JF. PMID: 30707108; PMCID: PMC6355229.
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PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
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Cilia-Associated Oxysterols Activate Smoothened. Mol Cell. 2018 10 18; 72(2):316-327.e5.
Raleigh DR, Sever N, Choksi PK, Sigg MA, Hines KM, Thompson BM, Elnatan D, Jaishankar P, Bisignano P, Garcia-Gonzalo FR, Krup AL, Eberl M, Byrne EFX, Siebold C, Wong SY, Renslo AR, Grabe M, McDonald JG, Xu L, Beachy PA, Reiter JF. PMID: 30340023; PMCID: PMC6503851.
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PubMed Mentions:
62 Fields:
Translation:
HumansAnimalsCells
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Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination. Neuron. 2018 07 11; 99(1):83-97.e7.
Park SM, Lim JS, Ramakrishina S, Kim SH, Kim WK, Lee J, Kang HC, Reiter JF, Kim DS, Kim HH, Lee JH. PMID: 29937275.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
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How the Ciliary Membrane Is Organized Inside-Out to Communicate Outside-In. Curr Biol. 2018 04 23; 28(8):R421-R434.
Garcia G, Raleigh DR, Reiter JF. PMID: 29689227; PMCID: PMC6434934.
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PubMed Mentions:
85 Fields:
Translation:
HumansAnimalsCells
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Subcellular localization of MC4R with ADCY3 at neuronal primary cilia underlies a common pathway for genetic predisposition to obesity. Nat Genet. 2018 02; 50(2):180-185.
Siljee JE, Wang Y, Bernard AA, Ersoy BA, Zhang S, Marley A, Von Zastrow M, Reiter JF, Vaisse C. PMID: 29311635; PMCID: PMC5805646.
View in:
PubMed Mentions:
113 Fields:
Translation:
HumansAnimalsCells
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Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways. Dev Cell. 2017 12 18; 43(6):744-762.e11.
Sigg MA, Menchen T, Lee C, Johnson J, Jungnickel MK, Choksi SP, Garcia G, Busengdal H, Dougherty GW, Pennekamp P, Werner C, Rentzsch F, Florman HM, Krogan N, Wallingford JB, Omran H, Reiter JF. PMID: 29257953; PMCID: PMC5752135.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansAnimalsCells
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Hedgehog signaling drives medulloblastoma growth via CDK6. J Clin Invest. 2018 01 02; 128(1):120-124.
Raleigh DR, Choksi PK, Krup AL, Mayer W, Santos N, Reiter JF. PMID: 29202464; PMCID: PMC5749513.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Erratum: Super-resolution microscopy reveals that disruption of ciliary transition-zone architecture causes Joubert syndrome. Nat Cell Biol. 2017 10 31; 19(11):1379.
Shi X, Garcia G, Van De Weghe JC, McGorty R, Pazour GJ, Doherty D, Huang B, Reiter JF. PMID: 29087383.
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PubMed Mentions:
6 Fields:
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Super-resolution microscopy reveals that disruption of ciliary transition-zone architecture causes Joubert syndrome. Nat Cell Biol. 2017 Oct; 19(10):1178-1188.
Shi X, Garcia G, Van De Weghe JC, McGorty R, Pazour GJ, Doherty D, Huang B, Reiter JF. PMID: 28846093; PMCID: PMC5695680.
View in:
PubMed Mentions:
80 Fields:
Translation:
HumansAnimalsCells
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Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis. Cell. 2017 Jul 13; 170(2):340-351.e12.
Kopinke D, Roberson EC, Reiter JF. PMID: 28709001; PMCID: PMC5617351.
View in:
PubMed Mentions:
105 Fields:
Translation:
AnimalsCells
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Genes and molecular pathways underpinning ciliopathies. Nat Rev Mol Cell Biol. 2017 Sep; 18(9):533-547.
Reiter JF, Leroux MR. PMID: 28698599; PMCID: PMC5851292.
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PubMed Mentions:
677 Fields:
Translation:
HumansAnimalsCells
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Cilia and Obesity. Cold Spring Harb Perspect Biol. 2017 Jul 05; 9(7).
Vaisse C, Reiter JF, Berbari NF. PMID: 28096262; PMCID: PMC5495057.
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PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
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Open Sesame: How Transition Fibers and the Transition Zone Control Ciliary Composition. Cold Spring Harb Perspect Biol. 2017 Feb 01; 9(2).
Garcia-Gonzalo FR, Reiter JF. PMID: 27770015; PMCID: PMC5287074.
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PubMed Mentions:
129 Fields:
Translation:
HumansAnimalsCells
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Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision. Cell. 2017 01 12; 168(1-2):264-279.e15.
Phua SC, Chiba S, Suzuki M, Su E, Roberson EC, Pusapati GV, Schurmans S, Setou M, Rohatgi R, Reiter JF, Ikegami K, Inoue T. PMID: 28086093; PMCID: PMC5660509.
View in:
PubMed Mentions:
170 Fields:
Translation:
AnimalsCells
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Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate. Neuron. 2016 Nov 23; 92(4):813-828.
Jayaraman D, Kodani A, Gonzalez DM, Mancias JD, Mochida GH, Vagnoni C, Johnson J, Krogan N, Harper JW, Reiter JF, Yu TW, Bae BI, Walsh CA. PMID: 27974163; PMCID: PMC5199216.
View in:
PubMed Mentions:
70 Fields:
Translation:
AnimalsCells
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Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex. Cell. 2016 Aug 25; 166(5):1147-1162.e15.
Zhang X, Chen MH, Wu X, Kodani A, Fan J, Doan R, Ozawa M, Ma J, Yoshida N, Reiter JF, Black DL, Kharchenko PV, Sharp PA, Walsh CA. PMID: 27565344; PMCID: PMC5248659.
View in:
PubMed Mentions:
177 Fields:
Translation:
HumansAnimalsCells
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A primer on the mouse basal body. Cilia. 2016; 5:17.
Garcia G, Reiter JF. PMID: 27114821; PMCID: PMC4843204.
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PubMed Mentions:
27
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MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone. PLoS Biol. 2016 Mar; 14(3):e1002416.
Li C, Jensen VL, Park K, Kennedy J, Garcia-Gonzalo FR, Romani M, De Mori R, Bruel AL, Gaillard D, Doray B, Lopez E, Rivière JB, Faivre L, Thauvin-Robinet C, Reiter JF, Blacque OE, Valente EM, Leroux MR. PMID: 26982032; PMCID: PMC4794247.
View in:
PubMed Mentions:
64 Fields:
Translation:
HumansAnimalsCells
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Endothelial primary cilia inhibit atherosclerosis. EMBO Rep. 2016 Feb; 17(2):156-66.
Dinsmore C, Reiter JF. PMID: 26769565; PMCID: PMC5290813.
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PubMed Mentions:
52 Fields:
Translation:
AnimalsCells
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Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling. PLoS Genet. 2015 Nov; 11(11):e1005627.
Yee LE, Garcia-Gonzalo FR, Bowie RV, Li C, Kennedy JK, Ashrafi K, Blacque OE, Leroux MR, Reiter JF. PMID: 26540106; PMCID: PMC4635004.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
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Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling. Dev Cell. 2015 Aug 24; 34(4):400-409.
Garcia-Gonzalo FR, Phua SC, Roberson EC, Garcia G, Abedin M, Schurmans S, Inoue T, Reiter JF. PMID: 26305592; PMCID: PMC4557815.
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PubMed Mentions:
175 Fields:
Translation:
AnimalsCells
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Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication. Elife. 2015 Aug 22; 4.
Kodani A, Yu TW, Johnson JR, Jayaraman D, Johnson TL, Al-Gazali L, Sztriha L, Partlow JN, Kim H, Krup AL, Dammermann A, Krogan NJ, Walsh CA, Reiter JF. PMID: 26297806; PMCID: PMC4574112.
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PubMed Mentions:
70 Fields:
Translation:
HumansCells
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TMEM231, mutated in orofaciodigital and Meckel syndromes, organizes the ciliary transition zone. J Cell Biol. 2015 Apr 13; 209(1):129-42.
Roberson EC, Dowdle WE, Ozanturk A, Garcia-Gonzalo FR, Li C, Halbritter J, Elkhartoufi N, Porath JD, Cope H, Ashley-Koch A, Gregory S, Thomas S, Sayer JA, Saunier S, Otto EA, Katsanis N, Davis EE, Attié-Bitach T, Hildebrandt F, Leroux MR, Reiter JF. PMID: 25869670; PMCID: PMC4395494.
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PubMed Mentions:
67 Fields:
Translation:
HumansAnimalsCells
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Ciliary vesicle formation: a prelude to ciliogenesis. Dev Cell. 2015 Mar 23; 32(6):665-6.
Yee LE, Reiter JF. PMID: 25805133; PMCID: PMC6434935.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Hair follicle and interfollicular epidermal stem cells make varying contributions to wound regeneration. Cell Cycle. 2015; 14(21):3408-17.
Vagnozzi AN, Reiter JF, Wong SY. PMID: 26398918; PMCID: PMC4825603.
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PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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Katanin p80 regulates human cortical development by limiting centriole and cilia number. Neuron. 2014 Dec 17; 84(6):1240-57.
Hu WF, Pomp O, Ben-Omran T, Kodani A, Henke K, Mochida GH, Yu TW, Woodworth MB, Bonnard C, Raj GS, Tan TT, Hamamy H, Masri A, Shboul M, Al Saffar M, Partlow JN, Al-Dosari M, Alazami A, Alowain M, Alkuraya FS, Reiter JF, Harris MP, Reversade B, Walsh CA. PMID: 25521379; PMCID: PMC4485387.
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PubMed Mentions:
54 Fields:
Translation:
HumansAnimalsCells
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C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals. Proc Natl Acad Sci U S A. 2014 Feb 11; 111(6):2164-9.
Ye X, Zeng H, Ning G, Reiter JF, Liu A. PMID: 24469809; PMCID: PMC3926046.
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PubMed Mentions:
89 Fields:
Translation:
AnimalsCells
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A central region of Gli2 regulates its localization to the primary cilium and transcriptional activity. J Cell Sci. 2014 Apr 01; 127(Pt 7):1500-10.
Santos N, Reiter JF. PMID: 24463817; PMCID: PMC3970560.
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PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
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Hedgehog signaling controls T cell killing at the immunological synapse. Science. 2013 Dec 06; 342(6163):1247-50.
de la Roche M, Ritter AT, Angus KL, Dinsmore C, Earnshaw CH, Reiter JF, Griffiths GM. PMID: 24311692; PMCID: PMC4022134.
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PubMed Mentions:
70 Fields:
Translation:
AnimalsCells
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Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration. Development. 2013 Dec; 140(24):4870-80.
Veniaminova NA, Vagnozzi AN, Kopinke D, Do TT, Murtaugh LC, Maillard I, Dlugosz AA, Reiter JF, Wong SY. PMID: 24198274; PMCID: PMC3848186.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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Thyroid-specific inactivation of KIF3A alters the TSH signaling pathway and leads to hypothyroidism. J Mol Endocrinol. 2013 Jun; 50(3):375-87.
D'Amico E, Gayral S, Massart C, Van Sande J, Reiter JF, Dumont JE, Robaye B, Schurmans S. PMID: 23511952; PMCID: PMC4404413.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages. EMBO J. 2013 Feb 20; 32(4):597-607.
Kodani A, Salomé Sirerol-Piquer M, Seol A, Garcia-Verdugo JM, Reiter JF. PMID: 23386061; PMCID: PMC3579144.
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PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCells
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Trask loss enhances tumorigenic growth by liberating integrin signaling and growth factor receptor cross-talk in unanchored cells. Cancer Res. 2013 Feb 01; 73(3):1168-79.
Spassov DS, Wong CH, Wong SY, Reiter JF, Moasser MM. PMID: 23243018; PMCID: PMC3563920.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Small molecule inhibitors of Smoothened ciliary localization and ciliogenesis. Proc Natl Acad Sci U S A. 2012 Aug 21; 109(34):13644-9.
Wu VM, Chen SC, Arkin MR, Reiter JF. PMID: 22864913; PMCID: PMC3427101.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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The base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalization. EMBO Rep. 2012 Jun 29; 13(7):608-18.
Reiter JF, Blacque OE, Leroux MR. PMID: 22653444; PMCID: PMC3388784.
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PubMed Mentions:
261 Fields:
Translation:
HumansAnimalsCells
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Scoring a backstage pass: mechanisms of ciliogenesis and ciliary access. J Cell Biol. 2012 Jun 11; 197(6):697-709.
Garcia-Gonzalo FR, Reiter JF. PMID: 22689651; PMCID: PMC3373398.
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PubMed Mentions:
134 Fields:
Translation:
HumansAnimalsCells
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A high-fat diet regulates gastrin and acid secretion through primary cilia. FASEB J. 2012 Aug; 26(8):3127-39.
Saqui-Salces M, Dowdle WE, Reiter JF, Merchant JL. PMID: 22516298; PMCID: PMC3405261.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal. PLoS Genet. 2012; 8(3):e1002576.
Hunkapiller J, Shen Y, Diaz A, Cagney G, McCleary D, Ramalho-Santos M, Krogan N, Ren B, Song JS, Reiter JF. PMID: 22438827; PMCID: PMC3305387.
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PubMed Mentions:
53 Fields:
Translation:
AnimalsCells
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Disruption of a ciliary B9 protein complex causes Meckel syndrome. Am J Hum Genet. 2011 Jul 15; 89(1):94-110.
Dowdle WE, Robinson JF, Kneist A, Sirerol-Piquer MS, Frints SG, Corbit KC, Zaghloul NA, Zaghloul NA, van Lijnschoten G, Mulders L, Verver DE, Zerres K, Reed RR, Attié-Bitach T, Johnson CA, García-Verdugo JM, Katsanis N, Bergmann C, Reiter JF. PMID: 21763481; PMCID: PMC3135817.
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PubMed Mentions:
86 Fields:
Translation:
HumansAnimalsCells
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A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition. Nat Genet. 2011 Jul 03; 43(8):776-84.
Garcia-Gonzalo FR, Corbit KC, Sirerol-Piquer MS, Ramaswami G, Otto EA, Noriega TR, Seol AD, Robinson JF, Bennett CL, Josifova DJ, García-Verdugo JM, Katsanis N, Hildebrandt F, Reiter JF. PMID: 21725307; PMCID: PMC3145011.
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PubMed Mentions:
373 Fields:
Translation:
HumansAnimalsCells
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Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell. 2011 May 13; 145(4):513-28.
Sang L, Miller JJ, Corbit KC, Giles RH, Brauer MJ, Otto EA, Baye LM, Wen X, Scales SJ, Kwong M, Huntzicker EG, Sfakianos MK, Sandoval W, Bazan JF, Kulkarni P, Garcia-Gonzalo FR, Seol AD, O'Toole JF, Held S, Reutter HM, Lane WS, Rafiq MA, Noor A, Ansar M, Devi AR, Sheffield VC, Slusarski DC, Vincent JB, Doherty DA, Hildebrandt F, Reiter JF, Jackson PK. PMID: 21565611; PMCID: PMC3383065.
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PubMed Mentions:
353 Fields:
Translation:
HumansAnimalsCells
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Role of epidermal primary cilia in the homeostasis of skin and hair follicles. Development. 2011 May; 138(9):1675-85.
Croyle MJ, Lehman JM, O'Connor AK, Wong SY, Malarkey EB, Iribarne D, Dowdle WE, Schoeb TR, Verney ZM, Athar M, Michaud EJ, Reiter JF, Yoder BK. PMID: 21429982; PMCID: PMC3074444.
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PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
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Wounding mobilizes hair follicle stem cells to form tumors. Proc Natl Acad Sci U S A. 2011 Mar 08; 108(10):4093-8.
Wong SY, Reiter JF. PMID: 21321207; PMCID: PMC3053984.
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PubMed Mentions:
65 Fields:
Translation:
AnimalsCells
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Crippling SWI-SNF makes tumors GLI-ful. Nat Med. 2010 Dec; 16(12):1374-6.
Reiter JF. PMID: 21135845.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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The ciliogenic protein Oral-Facial-Digital 1 regulates the neuronal differentiation of embryonic stem cells. Stem Cells Dev. 2011 May; 20(5):831-41.
Hunkapiller J, Singla V, Seol A, Reiter JF. PMID: 20873986; PMCID: PMC3128778.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Tilting at nodal windmills: planar cell polarity positions cilia to tell left from right. Dev Cell. 2010 Jul 20; 19(1):5-6.
Santos N, Reiter JF. PMID: 20643343; PMCID: PMC3998640.
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PubMed Mentions:
7 Fields:
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Vive la science! Vive le hérisson! EMBO Rep. 2010 Aug; 11(8):566-8.
Reiter JF, de Sauvage FJ. PMID: 20634805; PMCID: PMC2920439.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Ofd1, a human disease gene, regulates the length and distal structure of centrioles. Dev Cell. 2010 Mar 16; 18(3):410-24.
Singla V, Romaguera-Ros M, Garcia-Verdugo JM, Reiter JF. PMID: 20230748; PMCID: PMC2841064.
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PubMed Mentions:
152 Fields:
Translation:
HumansAnimalsCells
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Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation. Cell Stem Cell. 2010 Feb 05; 6(2):153-66.
Walker E, Chang WY, Hunkapiller J, Cagney G, Garcha K, Torchia J, Krogan NJ, Reiter JF, Stanford WL. PMID: 20144788; PMCID: PMC2849004.
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PubMed Mentions:
96 Fields:
Translation:
AnimalsCells
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Floxin, a resource for genetically engineering mouse ESCs. Nat Methods. 2010 Jan; 7(1):50-2.
Singla V, Hunkapiller J, Santos N, Seol AD, Norman AR, Wakenight P, Skarnes WC, Reiter JF. PMID: 19966808; PMCID: PMC2895430.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis. Nat Med. 2009 Sep; 15(9):1055-61.
Wong SY, Seol AD, So PL, Ermilov AN, Bichakjian CK, Epstein EH, Dlugosz AA, Reiter JF. PMID: 19701205; PMCID: PMC2895420.
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PubMed Mentions:
278 Fields:
Translation:
HumansAnimalsCells
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The extracellular domain of Smoothened regulates ciliary localization and is required for high-level Hh signaling. Curr Biol. 2009 Jun 23; 19(12):1034-9.
Aanstad P, Santos N, Corbit KC, Scherz PJ, Trinh le A, Salvenmoser W, Huisken J, Reiter JF, Stainier DY. PMID: 19464178; PMCID: PMC2892286.
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PubMed Mentions:
52 Fields:
Translation:
AnimalsCells
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Building it up and taking it down: the regulation of vertebrate ciliogenesis. Dev Dyn. 2008 Aug; 237(8):1972-81.
Santos N, Reiter JF. PMID: 18435467; PMCID: PMC3304540.
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PubMed Mentions:
64 Fields:
Translation:
HumansAnimalsCells
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A cilium is not a cilium is not a cilium: signaling contributes to ciliary morphological diversity. Dev Cell. 2008 May; 14(5):635-6.
Reiter JF. PMID: 18477443.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Neur-ons and neur-offs: regulators of neural induction in vertebrate embryos and embryonic stem cells. Hum Mol Genet. 2008 Apr 15; 17(R1):R60-6.
Gaulden J, Reiter JF. PMID: 18632699; PMCID: PMC6549723.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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The primary cilium at the crossroads of mammalian hedgehog signaling. Curr Top Dev Biol. 2008; 85:225-60.
Wong SY, Reiter JF. PMID: 19147008; PMCID: PMC2653622.
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PubMed Mentions:
116 Fields:
Translation:
AnimalsCells
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Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms. Nat Cell Biol. 2008 Jan; 10(1):70-6.
Corbit KC, Shyer AE, Dowdle WE, Gaulden J, Singla V, Chen MH, Chuang PT, Reiter JF. PMID: 18084282.
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PubMed Mentions:
293 Fields:
Translation:
AnimalsCells
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Vesicle transport, cilium formation, and membrane specialization: the origins of a sensory organelle. Proc Natl Acad Sci U S A. 2006 Dec 05; 103(49):18383-4.
Reiter JF, Mostov K. PMID: 17132734; PMCID: PMC1693671.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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The primary cilium as the cell's antenna: signaling at a sensory organelle. Science. 2006 Aug 04; 313(5787):629-33.
Singla V, Reiter JF. PMID: 16888132.
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PubMed Mentions:
541 Fields:
Translation:
HumansAnimalsCells
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Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition. Genes Dev. 2006 Jan 01; 20(1):22-7.
Reiter JF, Skarnes WC. PMID: 16357211; PMCID: PMC1356097.
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PubMed Mentions:
68 Fields:
Translation:
AnimalsCells
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Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli. Dev Biol. 2005 Nov 15; 287(2):378-89.
May SR, Ashique AM, Karlen M, Wang B, Shen Y, Zarbalis K, Reiter J, Ericson J, Peterson AS. PMID: 16229832.
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PubMed Mentions:
220 Fields:
Translation:
AnimalsCells
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Vertebrate Smoothened functions at the primary cilium. Nature. 2005 Oct 13; 437(7061):1018-21.
Corbit KC, Aanstad P, Singla V, Norman AR, Stainier DY, Reiter JF. PMID: 16136078.
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PubMed Mentions:
775 Fields:
Translation:
AnimalsCells
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Notch signaling can regulate endoderm formation in zebrafish. Dev Dyn. 2004 Apr; 229(4):756-62.
Kikuchi Y, Verkade H, Reiter JF, Kim CH, Chitnis AB, Kuroiwa A, Stainier DY. PMID: 15042699.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Bmp2b and Oep promote early myocardial differentiation through their regulation of gata5. Dev Biol. 2001 Jun 15; 234(2):330-8.
Reiter JF, Verkade H, Stainier DY. PMID: 11397003.
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PubMed Mentions:
25 Fields:
Translation:
Animals
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Multiple roles for Gata5 in zebrafish endoderm formation. Development. 2001 Jan; 128(1):125-35.
Reiter JF, Kikuchi Y, Stainier DY. PMID: 11092818.
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PubMed Mentions:
52 Fields:
Translation:
AnimalsCells
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The zebrafish bonnie and clyde gene encodes a Mix family homeodomain protein that regulates the generation of endodermal precursors. Genes Dev. 2000 May 15; 14(10):1279-89.
Kikuchi Y, Trinh LA, Reiter JF, Alexander J, Yelon D, Stainier DY. PMID: 10817762; PMCID: PMC316618.
View in:
PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
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Gata5 is required for the development of the heart and endoderm in zebrafish. Genes Dev. 1999 Nov 15; 13(22):2983-95.
Reiter JF, Alexander J, Rodaway A, Yelon D, Patient R, Holder N, Stainier DY. PMID: 10580005; PMCID: PMC317161.
View in:
PubMed Mentions:
144 Fields:
Translation:
AnimalsCells