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Thomas Hope, MD

Address4150 Clement St
San Francisco CA 94121
Phone415-221-4810
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    Collapse Biography 
    Collapse Awards and Honors
    SNMMI2016Marc Tetalman Award
    Society of Nuclear Medicine and Molecular Imaging2016Henkin Fellowship
    Society of Abdominal Radiology2014Wylie J. Dodds Research Award
    University of California, San Francisco 2012Alexander Margulis Society Outstanding Research Award
    Radiological Society of North America2012Roentgen Resident/Fellow Research Award
    Radiological Society of North America2010Presidents Circle Research Resident Grant
    ISMRM2007W.S. Moore Award Nominee
    Radiological Society of North America2006Trainee Research Prize

    Collapse Overview 
    Collapse overview
    Thomas Hope, MD, is an Assistant Professor in Residence in the Abdominal Imaging and Nuclear Medicine sections at UCSF and the San Francisco Veterans Affairs Medical Center. In 2007, he received his medical degree from Stanford University School of Medicine and he completed a one-year internship at Kaiser Permanente, San Francisco. From 2008-2012, Dr. Hope completed a residency in Diagnostic Radiology at the University of California, San Francisco, followed by a clinical fellowship in Body MRI and Nuclear Medicine from Stanford Medical Center in 2013.

    Dr. Hope’s main research focus is on novel imaging agents. He is the principle investigator on the Ga-68 DOTA-TOC IND at UCSF and the Ga-68 HBED-CC PSMA IND at UCSF. He has combined his interest in MR imaging with PET in the simultaneous modality PET/MRI, helping lead the development of the clinical PET/MRI program. Additionally he is developing the PRRT (peptide receptor radionuclide therapy) program for neuroendocrine tumors at UCSF.

    Dr. Hope has published 30 peer-reviewed articles, including 17 first author publications.

    Expertise:
    Abdominal Imaging and Nuclear Medicine

    Professional Interests:
    Novel imaging agents, PET/MR, prostate cancer, neuroendocrine tumor, targeted radiotherapy

    Education and Training:
    • Medical School: Stanford University School of Medicine, California
    • Internship: Kaiser Permanente, San Francisco, California
    • Residency: University of California, San Francisco - Diagnostic Radiology
    • Fellowship: Stanford Medical Center, California - Body MRI and Nuclear Medicine
    • California Medical License
    • American Board of Radiology, Certificate in Diagnostic Radiology
    • American Board of Nuclear Medicine, Certificate in Nuclear Medicine


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    Collapse Bibliographic 
    Collapse Selected Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Hope T, Aslam R, Weinstein S, Yeh BM, Corvera CU, Monto A, Yee J. Change in Liver Imaging Reporting and Data System Characterization of Focal Liver Lesions Using Gadoxetate Disodium Magnetic Resonance Imaging Compared With Contrast-Enhanced Computed Tomography. J Comput Assist Tomogr. 2016 Oct 31. PMID: 27801693.
      View in: PubMed
    2. Ikram NS, Yee J, Weinstein S, Yeh BM, Corvera CU, Monto A, Hope T. Multiple arterial phase MRI of arterial hypervascular hepatic lesions: improved arterial phase capture and lesion enhancement. Abdom Radiol (NY). 2016 Oct 21. PMID: 27770162.
      View in: PubMed
    3. Zukotynski K, Jadvar H, Hope T, Subramaniam RM, Van Loon K, Varma M, Niederkohr RD, et al. SNMMI Comment on the 2016 Society of Surgical Oncology "Choosing Wisely" Recommendation on the Use of PET/CT in Colorectal Cancer. J Nucl Med. 2016 Sep 29. PMID: 27688471.
      View in: PubMed
    4. Hope T, Truillet CC, Ehman EC, Afshar-Oromieh A, Aggarwal R, Ryan CJ, Carroll PR, Small EJ, Evans MJ. Imaging Response to Androgen Receptor Inhibition Using 68Ga-PSMA-11 PET: First Human Experience. J Nucl Med. 2016 Sep 22. PMID: 27660139.
      View in: PubMed
    5. Ehman EC, Umetsu SE, Ohliger MA, Fidelman N, Ferrell LD, Yeh BM, Yee J, Hope T, et al. Imaging prediction of residual hepatocellular carcinoma after locoregional therapy in patients undergoing liver transplantation or partial hepatectomy. Abdom Radiol (NY). 2016 Aug 3. PMID: 27484789.
      View in: PubMed
    6. Hope T, Aggarwal RR, Westphalen AC, Cooperberg MR, Greene KL, et al. Targeted PET imaging for prostate-specific membrane antigen in prostate cancer. Future Oncol. 2016 Jul 25. PMID: 27453303.
      View in: PubMed
    7. Kluijfhout WP, Venkatesh S, Beninato T, Vriens MR, Duh QY, Wilson DM, Hope TA, Suh I. Performance of magnetic resonance imaging in the evaluation of first-time and reoperative primary hyperparathyroidism. Surgery. 2016 Sep; 160(3):747-54. PMID: 27318765.
      View in: PubMed
    8. Afshar-Oromieh A, Hetzheim H, Kübler W, Kratochwil C, Giesel FL, Hope T, Eder M, Eisenhut M, Kopka K, Haberkorn U. Radiation dosimetry of (68)Ga-PSMA-11 (HBED-CC) and preliminary evaluation of optimal imaging timing. Eur J Nucl Med Mol Imaging. 2016 Aug; 43(9):1611-20. PMID: 27260521.
      View in: PubMed
    9. Ehman EC, Behr SC, Umetsu SE, Fidelman N, Yeh BM, Ferrell LD, Hope TA. Rate of observation and inter-observer agreement for LI-RADS major features at CT and MRI in 184 pathology proven hepatocellular carcinomas. Abdom Radiol (NY). 2016 May; 41(5):963-9. PMID: 27193793.
      View in: PubMed
    10. Hicks RM, Yee J, Ohliger MA, Weinstein S, Kao J, Ikram NS, Hope T. Comparison of diffusion-weighted imaging and T2-weighted single shot fast spin-echo: Implications for LI-RADS characterization of hepatocellular carcinoma. Magn Reson Imaging. 2016 Sep; 34(7):915-21. PMID: 27108359.
      View in: PubMed
    11. Becker-Weidman DJ, Hope TA, Doshi PH, Patel A, Mitchell DG. Transient washout of hepatic hemangiomas: Potential pitfall mimicking malignancy. Radiol Case Rep. 2016 Jun; 11(2):62-6. PMID: 27257451.
      View in: PubMed
    12. Kim SY, Wu EH, Park SH, Wang ZJ, Hope T, Yee J, Zhao LQ, Chang WC, Yeh BM. Comparison of hepatocellular carcinoma conspicuity on hepatobiliary phase images with gadoxetate disodium vs. delayed phase images with extracellular cellular contrast agent. Abdom Radiol (NY). 2016 Mar 12. PMID: 26971341.
      View in: PubMed
    13. Vasanawala SS, Nguyen KL, Hope MD, Bridges MD, Hope T, Reeder SB, Bashir MR. Safety and technique of ferumoxytol administration for MRI. Magn Reson Med. 2016 May; 75(5):2107-11. PMID: 26890830.
      View in: PubMed
    14. Hope TA, Verdin EF, Bergsland EK, Ohliger MA, Corvera CU, Nakakura EK. Correcting for respiratory motion in liver PET/MRI: preliminary evaluation of the utility of bellows and navigated hepatobiliary phase imaging. EJNMMI Phys. 2015 Dec; 2(1):21. PMID: 26501822; PMCID: PMC4573645.
    15. Hope T, Petkovska I, Saranathan M, Hargreaves BA, Vasanawala SS. Combined parenchymal and vascular imaging: High spatiotemporal resolution arterial evaluation of hepatocellular carcinoma. J Magn Reson Imaging. 2016 Apr; 43(4):859-65. PMID: 26340309.
      View in: PubMed
    16. Hope TA, Pampaloni MH, Nakakura E, VanBrocklin H, Slater J, Jivan S, Aparici CM, Yee J, Bergsland E. Simultaneous (68)Ga-DOTA-TOC PET/MRI with gadoxetate disodium in patients with neuroendocrine tumor. Abdom Imaging. 2015 Aug; 40(6):1432-40. PMID: 25820755.
      View in: PubMed
    17. Burris NS, Johnson KM, Larson PE, Hope MD, Nagle SK, Behr SC, Hope T. Detection of Small Pulmonary Nodules with Ultrashort Echo Time Sequences in Oncology Patients by Using a PET/MR System. Radiology. 2016 Jan; 278(1):239-46. PMID: 26133050.
      View in: PubMed
    18. Hope MD, Hope TA, Zhu C, Faraji F, Haraldsson H, Ordovas KG, Saloner D. Vascular Imaging With Ferumoxytol as a Contrast Agent. AJR Am J Roentgenol. 2015 Sep; 205(3):W366-73. PMID: 26102308.
      View in: PubMed
    19. Hope TA, Aggarwal R, Simko JP, VanBrocklin HF, Ryan CJ. Somatostatin imaging of neuroendocrine-differentiated prostate cancer. Clin Nucl Med. 2015 Jun; 40(6):540-1. PMID: 25783510.
      View in: PubMed
    20. Kim SY, Park SH, Wu EH, Wang ZJ, Hope TA, Chang WC, Yeh BM. Transient respiratory motion artifact during arterial phase MRI with gadoxetate disodium: risk factor analyses. AJR Am J Roentgenol. 2015 Jun; 204(6):1220-7. PMID: 26001231.
      View in: PubMed
    21. Stephens EH, Hope TA, Kari FA, Kvitting JP, Liang DH, Herfkens RJ, Miller DC. Greater asymmetric wall shear stress in Sievers' type 1/LR compared with 0/LAT bicuspid aortic valves after valve-sparing aortic root replacement. J Thorac Cardiovasc Surg. 2015 Jul; 150(1):59-68. PMID: 25956338.
      View in: PubMed
    22. Hope TA, Fowler KJ, Sirlin CB, Costa EA, Yee J, Yeh BM, Heiken JP. Hepatobiliary agents and their role in LI-RADS. Abdom Imaging. 2015 Mar; 40(3):613-25. PMID: 25287679.
      View in: PubMed
    23. Jacobs MA, Weinstein S, Hope TA, Aslam R, Yee J, Coakley F. Neuroendocrine tumors: beyond the abdomen. J Comput Assist Tomogr. 2014 Nov-Dec; 38(6):898-914. PMID: 25162290.
      View in: PubMed
    24. Hope TA, Ohliger MA, Qayyum A. MR imaging of diffuse liver disease: from technique to diagnosis. Radiol Clin North Am. 2014 Jul; 52(4):709-24. PMID: 24889168.
      View in: PubMed
    25. Hope MD, Hope TA. Functional and molecular imaging techniques in aortic aneurysm disease. Curr Opin Cardiol. 2013 Nov; 28(6):609-18. PMID: 24030165.
      View in: PubMed
    26. Hope TA, Kvitting JP, Hope MD, Miller DC, Markl M, Herfkens RJ. Evaluation of Marfan patients status post valve-sparing aortic root replacement with 4D flow. Magn Reson Imaging. 2013 Nov; 31(9):1479-84. PMID: 23706513.
      View in: PubMed
    27. Hope TA, Saranathan M, Petkovska I, Hargreaves BA, Herfkens RJ, Vasanawala SS. Improvement of gadoxetate arterial phase capture with a high spatio-temporal resolution multiphase three-dimensional SPGR-Dixon sequence. J Magn Reson Imaging. 2013 Oct; 38(4):938-45. PMID: 23371926.
      View in: PubMed
    28. Durack JC, Hope TA, Seo Y, Saeed M, He J, Wilson MW, Kerlan RK, Ring EJ. Intravenous vasopressin for the prevention of nontarget gastrointestinal embolization during liver-directed cancer treatment: experimental study in a porcine model. J Vasc Interv Radiol. 2012 Nov; 23(11):1505-12. PMID: 22974656.
      View in: PubMed
    29. Hope TA, Leboit PE, High WA, Fu Y, Brasch RC. Evaluation of imatinib mesylate as a possible treatment for nephrogenic systemic fibrosis in a rat model. Magn Reson Imaging. 2013 Jan; 31(1):139-44. PMID: 22898683.
      View in: PubMed
    30. Hope TA, Doherty A, Fu Y, Aslam R, Qayyum A, Brasch RC. Gadolinium accumulation and fibrosis in the liver after administration of gadoxetate disodium in a rat model of active hepatic fibrosis. Radiology. 2012 Aug; 264(2):423-7. PMID: 22570507.
      View in: PubMed
    31. Hope TA, Hope MD. Improved risk assessment for abdominal aortic aneurysm rupture: off-the-wall imaging. J Am Coll Cardiol. 2011 Dec 6; 58(24):2531-2. PMID: 22133854.
      View in: PubMed
    32. Hope MD, Hope TA, Crook SE, Ordovas KG, Urbania TH, Alley MT, Higgins CB. 4D flow CMR in assessment of valve-related ascending aortic disease. JACC Cardiovasc Imaging. 2011 Jul; 4(7):781-7. PMID: 21757170.
      View in: PubMed
    33. McGowan PO, Hope TA, Meck WH, Kelsoe G, Williams CL. Impaired social recognition memory in recombination activating gene 1-deficient mice. Brain Res. 2011 Apr 6; 1383:187-95. PMID: 21354115; PMCID: PMC3436067.
    34. Hope MD, Hope TA, Urbania TH, Higgins CB. Four-dimensional flow magnetic resonance imaging with wall shear stress analysis before and after repair of aortopulmonary fistula. Circ Cardiovasc Imaging. 2010 Nov; 3(6):766-8. PMID: 21081744.
      View in: PubMed
    35. Hope MD, Hope TA, Meadows AK, Ordovas KG, Urbania TH, Alley MT, Higgins CB. Bicuspid aortic valve: four-dimensional MR evaluation of ascending aortic systolic flow patterns. Radiology. 2010 Apr; 255(1):53-61. PMID: 20308444.
      View in: PubMed
    36. Hope MD, Meadows AK, Hope TA, Ordovas KG, Saloner D, Reddy GP, Alley MT, Higgins CB. Clinical evaluation of aortic coarctation with 4D flow MR imaging. J Magn Reson Imaging. 2010 Mar; 31(3):711-8. PMID: 20187217.
      View in: PubMed
    37. Hope TA, High WA, Leboit PE, Chaopathomkul B, Rogut VS, Herfkens RJ, Brasch RC. Nephrogenic systemic fibrosis in rats treated with erythropoietin and intravenous iron. Radiology. 2009 Nov; 253(2):390-8. PMID: 19789237.
      View in: PubMed
    38. Cebral JR, Putman CM, Alley MT, Hope T, Bammer R, Calamante F. Hemodynamics in Normal Cerebral Arteries: Qualitative Comparison of 4D Phase-Contrast Magnetic Resonance and Image-Based Computational Fluid Dynamics. J Eng Math. 2009 Aug 1; 64(4):367-378. PMID: 19684874.
      View in: PubMed
    39. Hope TA, Hope MD, Purcell DD, von Morze C, Vigneron DB, Alley MT, Dillon WP. Evaluation of intracranial stenoses and aneurysms with accelerated 4D flow. Magn Reson Imaging. 2010 Jan; 28(1):41-6. PMID: 19577400.
      View in: PubMed
    40. Hope TA, Herfkens RJ, Denianke KS, LeBoit PE, Hung YY, Weil E. Nephrogenic systemic fibrosis in patients with chronic kidney disease who received gadopentetate dimeglumine. Invest Radiol. 2009 Mar; 44(3):135-9. PMID: 19151610.
      View in: PubMed
    41. Hope TA, Zarins CK, Herfkens RJ. Initial experience characterizing a type I endoleak from velocity profiles using time-resolved three-dimensional phase-contrast MRI. J Vasc Surg. 2009 Jun; 49(6):1580-4. PMID: 19223146.
      View in: PubMed
    42. Hope MD, Purcell DD, Hope TA, von Morze C, Vigneron DB, Alley MT, Dillon WP. Complete intracranial arterial and venous blood flow evaluation with 4D flow MR imaging. AJNR Am J Neuroradiol. 2009 Feb; 30(2):362-6. PMID: 18653687.
      View in: PubMed
    43. Hope MD, Meadows AK, Hope TA, Ordovas KG, Reddy GP, Alley MT, Higgins CB. Images in cardiovascular medicine. Evaluation of bicuspid aortic valve and aortic coarctation with 4D flow magnetic resonance imaging. Circulation. 2008 May 27; 117(21):2818-9. PMID: 18506021.
      View in: PubMed
    44. Hope TA, Herfkens RJ. Imaging of the thoracic aorta with time-resolved three-dimensional phase-contrast MRI: a review. Semin Thorac Cardiovasc Surg. 2008; 20(4):358-64. PMID: 19251177.
      View in: PubMed
    45. Hope TA, Markl M, Wigström L, Alley MT, Miller DC, Herfkens RJ. Comparison of flow patterns in ascending aortic aneurysms and volunteers using four-dimensional magnetic resonance velocity mapping. J Magn Reson Imaging. 2007 Dec; 26(6):1471-9. PMID: 17968892.
      View in: PubMed
    46. Bammer R, Hope TA, Aksoy M, Alley MT. Time-resolved 3D quantitative flow MRI of the major intracranial vessels: initial experience and comparative evaluation at 1.5T and 3.0T in combination with parallel imaging. Magn Reson Med. 2007 Jan; 57(1):127-40. PMID: 17195166; PMCID: PMC3985842.
    47. Keene JM, Hope T. Hyperphagia in dementia: 1. The use of an objective and reliable method for measuring hyperphagia in people with dementia. Appetite. 1997 Apr; 28(2):151-65. PMID: 9158849.
      View in: PubMed
    48. Hope T, Fairburn CG. The Present Behavioural Examination (PBE): the development of an interview to measure current behavioural abnormalities. Psychol Med. 1992 Feb; 22(1):223-30. PMID: 1574559.
      View in: PubMed
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