Sign in to edit your profile (add interests, mentoring, photo, etc.)

    Frank McCormick, PhD, FRS

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentHDF Comprehensive Cancer Ctr
    Address1450 3rd Street
    San Francisco CA 94158
    Phone415-502-1710

       Overview 
       Overview
      Frank McCormick, PhD, FRS, is Professor Emeritus of the UCSF Helen Diller Family Comprehensive Cancer Center. Prior to joining the UCSF faculty, Dr. McCormick pursued cancer-related work with several Bay Area biotechnology firms and held positions with Cetus Corporation (Director of Molecular Biology, 1981-1990; Vice President of Research, 1990-1991) and Chiron Corporation, where he was Vice President of Research from 1991 to 1992. In 1992 he founded Onyx Pharmaceuticals, a company dedicated to developing new cancer therapies, and served as its Chief Scientific Officer until 1996. At Onyx Pharmaceuticals, he initiated and led drug discovery efforts that led to the approval of Sorafenib in 2005 for treatment of renal cell cancer, and for liver cancer in 2007, and the approval of ONYX-015 in 2006 in China for treatment of nasopharyngeal cancer. Sorafenib is being tested in multiple indications worldwide. In addition, Dr. McCormick’s group led to the identification of a CDK4 kinase inhibitor. Dr. McCormick's current research interests center on the fundamental differences between normal and cancer cells that can allow the discovery of novel therapeutic strategies.

      Dr. McCormick holds the David A. Wood Chair of Tumor Biology and Cancer Research at UCSF. Dr. McCormick is the author of over 285 scientific publications and holds 20 issued patents. He also served as President, 2012-2013 for the American Association for Cancer Research (AACR). More recently, he has taken a leadership role at the Frederick National Lab for Cancer Research, overseeing an NCI supported national effort to develop therapies against Ras-driven cancers. These cancers include most pancreatic cancers, and many colorectal and lung cancers, and are amongst the most difficult cancers to treat.


       ORNG Applications 
       Websites
       In The News
       NIH Awarded Grants
       Global Health
       More Info

       Bibliographic 
       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Guinney J, Dienstmann R, Ferté C, Friend S, McCormick F. Social interactomes for enabling research communities. Cancer Discov. 2014 Nov; 4(11):1265-8.
        View in: PubMed
      2. Phuchareon J, van Zante A, Overdevest JB, McCormick F, Eisele DW, Tetsu O. c-Kit Expression is Rate-Limiting for Stem Cell Factor-Mediated Disease Progression in Adenoid Cystic Carcinoma of the Salivary Glands. Transl Oncol. 2014 Oct; 7(5):537-45.
        View in: PubMed
      3. Sos ML, Levin RS, Gordan JD, Oses-Prieto JA, Webber JT, Salt M, Hann B, Burlingame AL, McCormick F, Bandyopadhyay S, Shokat KM. Oncogene Mimicry as a Mechanism of Primary Resistance to BRAF Inhibitors. Cell Rep. 2014 Aug 21; 8(4):1037-48.
        View in: PubMed
      4. Yuan TL, Fellmann C, Lee CS, Ritchie CD, Thapar V, Lee LC, Hsu DJ, Grace D, Carver JO, Zuber J, Luo J, McCormick F, Lowe SW. Development of siRNA Payloads to Target KRAS-Mutant Cancer. Cancer Discov. 2014 Oct; 4(10):1182-97.
        View in: PubMed
      5. Holderfield M, Deuker MM, McCormick F, McMahon M. Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond. Nat Rev Cancer. 2014 Jun 24; 14(7):455-67.
        View in: PubMed
      6. Thai M, Graham NA, Braas D, Nehil M, Komisopoulou E, Kurdistani SK, McCormick F, Graeber TG, Christofk HR. Adenovirus E4ORF1-Induced MYC Activation Promotes Host Cell Anabolic Glucose Metabolism and Virus Replication. Cell Metab. 2014 Apr 1; 19(4):694-701.
        View in: PubMed
      7. Stephen AG, Esposito D, Bagni RK, McCormick F. Dragging ras back in the ring. Cancer Cell. 2014 Mar 17; 25(3):272-81.
        View in: PubMed
      8. Holderfield M, Lorenzana E, Weisburd B, Lomovasky L, Boussemart L, Lacroix L, Tomasic G, Favre M, Vagner S, Robert C, Ghoddusi M, Daniel D, Pryer N, McCormick F, Stuart D. Vemurafenib Cooperates with HPV to Promote Initiation of Cutaneous Tumors. Cancer Res. 2014 Apr 15; 74(8):2238-45.
        View in: PubMed
      9. Kashiyama T, Oda K, Ikeda Y, Shiose Y, Hirota Y, Inaba K, Makii C, Kurikawa R, Miyasaka A, Koso T, Fukuda T, Tanikawa M, Shoji K, Sone K, Arimoto T, Wada-Hiraike O, Kawana K, Nakagawa S, Matsuda K, McCormick F, Aburatani H, Yano T, Osuga Y, Fujii T. Antitumor Activity and Induction of TP53-Dependent Apoptosis toward Ovarian Clear Cell Adenocarcinoma by the Dual PI3K/mTOR Inhibitor DS-7423. PLoS One. 2014; 9(2):e87220.
        View in: PubMed
      10. Widemann BC, Acosta MT, Ammoun S, Belzberg AJ, Bernards A, Blakeley J, Bretscher A, Cichowski K, Clapp DW, Dombi E, Evans GD, Ferner R, Fernandez-Valle C, Fisher MJ, Giovannini M, Gutmann DH, Hanemann CO, Hennigan R, Huson S, Ingram D, Kissil J, Korf BR, Legius E, Packer RJ, McClatchey AI, McCormick F, North K, Pehrsson M, Plotkin SR, Ramesh V, Ratner N, Schirmer S, Sherman L, Schorry E, Stevenson D, Stewart DR, Ullrich N, Bakker AC, Morrison H. CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies. Am J Med Genet A. 2014 Mar; 164(3):563-78.
        View in: PubMed
      11. Salt MB, Bandyopadhyay S, McCormick F. Epithelial-to-Mesenchymal Transition Rewires the Molecular Path to PI3K-Dependent Proliferation. Cancer Discov. 2014 Feb; 4(2):186-99.
        View in: PubMed
      12. Yuan TL, McCormick F. Killing Tumors by Keeping Ras and PI3' Kinase Apart. Cancer Cell. 2013 Nov 11; 24(5):562-3.
        View in: PubMed
      13. Nan X, Collisson EA, Lewis S, Huang J, Tamgüney TM, Liphardt JT, McCormick F, Gray JW, Chu S. Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling. Proc Natl Acad Sci U S A. 2013 Nov 12; 110(46):18519-24.
        View in: PubMed
      14. Timmerman LA, Holton T, Yuneva M, Louie RJ, Padró M, Daemen A, Hu M, Chan DA, Ethier SP, van 't Veer LJ, Polyak K, McCormick F, Gray JW. Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target. Cancer Cell. 2013 Oct 14; 24(4):450-65.
        View in: PubMed
      15. Lyons J, Bastian BC, McCormick F. MC1R and cAMP signaling inhibit cdc25B activity and delay cell cycle progression in melanoma cells. Proc Natl Acad Sci U S A. 2013 Aug 20; 110(34):13845-50.
        View in: PubMed
      16. Holderfield M, Merritt H, Chan J, Wallroth M, Tandeske L, Zhai H, Tellew J, Hardy S, Hekmat-Nejad M, Stuart DD, McCormick F, Nagel TE. RAF inhibitors activate the MAPK pathway by relieving inhibitory autophosphorylation. Cancer Cell. 2013 May 13; 23(5):594-602.
        View in: PubMed
      17. McCormick F, Cvetanovich GL, Kim JM, Harris JD, Gupta AK, Abrams GD, Romeo AA, Provencher MT. An assessment of the quality of rotator cuff randomized controlled trials: utilizing the Jadad score and CONSORT criteria. J Shoulder Elbow Surg. 2013 Sep; 22(9):1180-5.
        View in: PubMed
      18. Young A, Lou D, McCormick F. Oncogenic and wild-type Ras play divergent roles in the regulation of mitogen-activated protein kinase signaling. Cancer Discov. 2013 Jan; 3(1):112-23.
        View in: PubMed
      19. Stowe IB, Mercado EL, Stowe TR, Bell EL, Oses-Prieto JA, Hernández H, Burlingame AL, McCormick F. A shared molecular mechanism underlies the human rasopathies Legius syndrome and Neurofibromatosis-1. Genes Dev. 2012 Jul 1; 26(13):1421-6.
        View in: PubMed
      20. Shoji K, Oda K, Kashiyama T, Ikeda Y, Nakagawa S, Sone K, Miyamoto Y, Hiraike H, Tanikawa M, Miyasaka A, Koso T, Matsumoto Y, Wada-Hiraike O, Kawana K, Kuramoto H, McCormick F, Aburatani H, Yano T, Kozuma S, Taketani Y. Genotype-dependent efficacy of a dual PI3K/mTOR inhibitor, NVP-BEZ235, and an mTOR inhibitor, RAD001, in endometrial carcinomas. PLoS One. 2012; 7(5):e37431.
        View in: PubMed
      21. McCormick F. Cancer therapy based on oncogene addiction. J Surg Oncol. 2011 May 1; 103(6):464-7.
        View in: PubMed
      22. Rauen KA, Banerjee A, Bishop WR, Lauchle JO, McCormick F, McMahon M, Melese T, Munster PN, Nadaf S, Packer RJ, Sebolt-Leopold J, Viskochil DH. Costello and cardio-facio-cutaneous syndromes: Moving toward clinical trials in RASopathies. Am J Med Genet C Semin Med Genet. 2011 May 15; 157C(2):136-46.
        View in: PubMed
      23. Gysin S, Salt M, Young A, McCormick F. Therapeutic strategies for targeting ras proteins. Genes Cancer. 2011 Mar; 2(3):359-72.
        View in: PubMed
      24. McCormick F. Mutant onco-proteins as drug targets: successes, failures, and future prospects. Curr Opin Genet Dev. 2011 Feb; 21(1):29-33.
        View in: PubMed
      25. Lee SH, McCormick F, Saya H. Mad2 inhibits the mitotic kinesin MKlp2. J Cell Biol. 2010 Dec 13; 191(6):1069-77.
        View in: PubMed
      26. van Zeeburg HJ, Huizenga A, Brink A, van den Doel PB, Zhu ZB, McCormick F, Brakenhoff RH, van Beusechem VW. Comparison of oncolytic adenoviruses for selective eradication of oral cancer and pre-cancerous lesions. Gene Ther. 2010 Dec; 17(12):1517-24.
        View in: PubMed
      27. Lyle C, McCormick F. Integrin alphavbeta5 is a primary receptor for adenovirus in CAR-negative cells. Virol J. 2010; 7:148.
        View in: PubMed
      28. Ishida S, McCormick F, Smith-McCune K, Hanahan D. Enhancing tumor-specific uptake of the anticancer drug cisplatin with a copper chelator. Cancer Cell. 2010 Jun 15; 17(6):574-83.
        View in: PubMed
      29. Harris TJ, McCormick F. The molecular pathology of cancer. Nat Rev Clin Oncol. 2010 May; 7(5):251-65.
        View in: PubMed
      30. Phan VT, Ding VW, Li F, Chalkley RJ, Burlingame A, McCormick F. The RasGAP proteins Ira2 and neurofibromin are negatively regulated by Gpb1 in yeast and ETEA in humans. Mol Cell Biol. 2010 May; 30(9):2264-79.
        View in: PubMed
      31. Kissil JL, Blakeley JO, Ferner RE, Huson SM, Kalamarides M, Mautner VF, McCormick F, Morrison H, Packer R, Ramesh V, Ratner N, Rauen KA, Stevenson DA, Hunter-Schaedle K, North K. What's new in neurofibromatosis? Proceedings from the 2009 NF Conference: new frontiers. Am J Med Genet A. 2010 Feb; 152A(2):269-83.
        View in: PubMed
      32. McCormick F. How blocking Raf activates the MAPK pathway. Pigment Cell Melanoma Res. 2010 Apr; 23(2):187-9.
        View in: PubMed
      33. Murayama-Hosokawa S, Oda K, Nakagawa S, Ishikawa S, Yamamoto S, Shoji K, Ikeda Y, Uehara Y, Fukayama M, McCormick F, Yano T, Taketani Y, Aburatani H. Genome-wide single-nucleotide polymorphism arrays in endometrial carcinomas associate extensive chromosomal instability with poor prognosis and unveil frequent chromosomal imbalances involved in the PI3-kinase pathway. Oncogene. 2010 Apr 1; 29(13):1897-908.
        View in: PubMed
      34. Rauen KA, Schoyer L, McCormick F, Lin AE, Allanson JE, Stevenson DA, Gripp KW, Neri G, Carey JC, Legius E, Tartaglia M, Schubbert S, Roberts AE, Gelb BD, Shannon K, Gutmann DH, McMahon M, Guerra C, Fagin JA, Yu B, Aoki Y, Neel BG, Balmain A, Drake RR, Nolan GP, Zenker M, Bollag G, Sebolt-Leopold J, Gibbs JB, Silva AJ, Patton EE, Viskochil DH, Kieran MW, Korf BR, Hagerman RJ, Packer RJ, Melese T. Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back. Am J Med Genet A. 2010 Jan; 152A(1):4-24.
        View in: PubMed
      35. Fan QW, Cheng C, Knight ZA, Haas-Kogan D, Stokoe D, James CD, McCormick F, Shokat KM, Weiss WA. EGFR signals to mTOR through PKC and independently of Akt in glioma. Sci Signal. 2009; 2(55):ra4.
        View in: PubMed
      36. Mirzoeva OK, Das D, Heiser LM, Bhattacharya S, Siwak D, Gendelman R, Bayani N, Wang NJ, Neve RM, Guan Y, Hu Z, Knight Z, Feiler HS, Gascard P, Parvin B, Spellman PT, Shokat KM, Wyrobek AJ, Bissell MJ, McCormick F, Kuo WL, Mills GB, Gray JW, Korn WM. Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition. Cancer Res. 2009 Jan 15; 69(2):565-72.
        View in: PubMed
      37. Young A, Lyons J, Miller AL, Phan VT, Alarcón IR, McCormick F. Ras signaling and therapies. Adv Cancer Res. 2009; 102:1-17.
        View in: PubMed
      38. Lee SH, Sterling H, Burlingame A, McCormick F. Tpr directly binds to Mad1 and Mad2 and is important for the Mad1-Mad2-mediated mitotic spindle checkpoint. Genes Dev. 2008 Nov 1; 22(21):2926-31.
        View in: PubMed
      39. Oda K, Okada J, Timmerman L, Rodriguez-Viciana P, Stokoe D, Shoji K, Taketani Y, Kuramoto H, Knight ZA, Shokat KM, McCormick F. PIK3CA cooperates with other phosphatidylinositol 3'-kinase pathway mutations to effect oncogenic transformation. Cancer Res. 2008 Oct 1; 68(19):8127-36.
        View in: PubMed
      40. Weisenberger DJ, Trinh BN, Campan M, Sharma S, Long TI, Ananthnarayan S, Liang G, Esteva FJ, Hortobagyi GN, McCormick F, Jones PA, Laird PW. DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight. Nucleic Acids Res. 2008 Aug; 36(14):4689-98.
        View in: PubMed
      41. Oehler VG, Qin J, Ramakrishnan R, Facer G, Ananthnarayan S, Cummings C, Deininger M, Shah N, McCormick F, Willis S, Daridon A, Unger M, Radich JP. Absolute quantitative detection of ABL tyrosine kinase domain point mutations in chronic myeloid leukemia using a novel nanofluidic platform and mutation-specific PCR. Leukemia. 2009 Feb; 23(2):396-9.
        View in: PubMed
      42. Kitagawa M, Aonuma M, Lee SH, Fukutake S, McCormick F. E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines. Oncogene. 2008 Sep 11; 27(40):5303-14.
        View in: PubMed
      43. Rauen KA, Hefner E, Carrillo K, Taylor J, Messier L, Aoki Y, Gripp KW, Matsubara Y, Proud VK, Hammond P, Allanson JE, Delrue MA, Axelrad ME, Lin AE, Doyle DA, Kerr B, Carey JC, McCormick F, Silva AJ, Kieran MW, Hinek A, Nguyen TT, Schoyer L. Molecular aspects, clinical aspects and possible treatment modalities for Costello syndrome: Proceedings from the 1st International Costello Syndrome Research Symposium 2007. Am J Med Genet A. 2008 May 1; 146A(9):1205-17.
        View in: PubMed
      44. Yeang CH, McCormick F, Levine A. Combinatorial patterns of somatic gene mutations in cancer. FASEB J. 2008 Aug; 22(8):2605-22.
        View in: PubMed
      45. Kitagawa M, Lee SH, McCormick F. Skp2 suppresses p53-dependent apoptosis by inhibiting p300. Mol Cell. 2008 Feb 1; 29(2):217-31.
        View in: PubMed
      46. Estep AL, Palmer C, McCormick F, Rauen KA. Mutation analysis of BRAF, MEK1 and MEK2 in 15 ovarian cancer cell lines: implications for therapy. PLoS One. 2007; 2(12):e1279.
        View in: PubMed
      47. Currie RJ, Freeman SJ, McCormick F, McGonigle RJ. Polycystic kidneys: a cautionary story. Br J Radiol. 2007 Dec; 80(960):e305-9.
        View in: PubMed
      48. Senawong T, Phuchareon J, Ohara O, McCormick F, Rauen KA, Tetsu O. Germline mutations of MEK in cardio-facio-cutaneous syndrome are sensitive to MEK and RAF inhibition: implications for therapeutic options. Hum Mol Genet. 2008 Feb 1; 17(3):419-30.
        View in: PubMed
      49. Jiang H, Gomez-Manzano C, Aoki H, Alonso MM, Kondo S, McCormick F, Xu J, Kondo Y, Bekele BN, Colman H, Lang FF, Fueyo J. Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: role of autophagic cell death. J Natl Cancer Inst. 2007 Sep 19; 99(18):1410-4.
        View in: PubMed
      50. McCormick F. Success and failure on the ras pathway. Cancer Biol Ther. 2007 Oct; 6(10):1654-9.
        View in: PubMed
      51. Iacovides DC, O'Shea CC, Oses-Prieto J, Burlingame A, McCormick F. Critical role for arginine methylation in adenovirus-infected cells. J Virol. 2007 Dec; 81(23):13209-17.
        View in: PubMed
      52. Ding VW, Lin LP, Chiang AL, McCormick F. Activation of p53 by Dishevelled independent of Wnt or planar polarity pathways. J Mol Med (Berl). 2007 Nov; 85(11):1281-9.
        View in: PubMed
      53. Okabe H, Lee SH, Phuchareon J, Albertson DG, McCormick F, Tetsu O. A critical role for FBXW8 and MAPK in cyclin D1 degradation and cancer cell proliferation. PLoS One. 2006; 1:e128.
        View in: PubMed
      54. Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T, Clark L, Bayani N, Coppe JP, Tong F, Speed T, Spellman PT, DeVries S, Lapuk A, Wang NJ, Kuo WL, Stilwell JL, Pinkel D, Albertson DG, Waldman FM, McCormick F, Dickson RB, Johnson MD, Lippman M, Ethier S, Gazdar A, Gray JW. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell. 2006 Dec; 10(6):515-27.
        View in: PubMed
      55. Lee SH, McCormick F. p97/DAP5 is a ribosome-associated factor that facilitates protein synthesis and cell proliferation by modulating the synthesis of cell cycle proteins. EMBO J. 2006 Sep 6; 25(17):4008-19.
        View in: PubMed
      56. Jiang H, McCormick F, Lang FF, Gomez-Manzano C, Fueyo J. Oncolytic adenoviruses as antiglioma agents. Expert Rev Anticancer Ther. 2006 May; 6(5):697-708.
        View in: PubMed
      57. Rodriguez-Viciana P, Oses-Prieto J, Burlingame A, Fried M, McCormick F. A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity. Mol Cell. 2006 Apr 21; 22(2):217-30.
        View in: PubMed
      58. Rodriguez-Viciana P, McCormick F. Ras ubiquitination: coupling spatial sorting and signal transmission. Cancer Cell. 2006 Apr; 9(4):243-4.
        View in: PubMed
      59. Rodriguez-Viciana P, Tetsu O, Tidyman WE, Estep AL, Conger BA, Cruz MS, McCormick F, Rauen KA. Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome. Science. 2006 Mar 3; 311(5765):1287-90.
        View in: PubMed
      60. Gomez-Manzano C, Alonso MM, Yung WK, McCormick F, Curiel DT, Lang FF, Jiang H, Bekele BN, Zhou X, Alemany R, Fueyo J. Delta-24 increases the expression and activity of topoisomerase I and enhances the antiglioma effect of irinotecan. Clin Cancer Res. 2006 Jan 15; 12(2):556-62.
        View in: PubMed
      61. You L, Kim J, He B, Xu Z, McCormick F, Jablons DM. Wnt-1 signal as a potential cancer therapeutic target. Drug News Perspect. 2006 Jan-Feb; 19(1):27-31.
        View in: PubMed
      62. Rodriguez-Viciana P, McCormick F. Characterization of interactions between ras family GTPases and their effectors. Methods Enzymol. 2006; 407:187-94.
        View in: PubMed
      63. Oda K, Stokoe D, Taketani Y, McCormick F. High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma. Cancer Res. 2005 Dec 1; 65(23):10669-73.
        View in: PubMed
      64. McCormick F. Future prospects for oncolytic therapy. Oncogene. 2005 Nov 21; 24(52):7817-9.
        View in: PubMed
      65. Mazieres J, You L, He B, Xu Z, Lee AY, Mikami I, McCormick F, Jablons DM. Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis. Oncogene. 2005 Aug 11; 24(34):5396-400.
        View in: PubMed
      66. Reid TR, Freeman S, Post L, McCormick F, Sze DY. Effects of Onyx-015 among metastatic colorectal cancer patients that have failed prior treatment with 5-FU/leucovorin. Cancer Gene Ther. 2005 Aug; 12(8):673-81.
        View in: PubMed
      67. Macrae M, Neve RM, Rodriguez-Viciana P, Haqq C, Yeh J, Chen C, Gray JW, McCormick F. A conditional feedback loop regulates Ras activity through EphA2. Cancer Cell. 2005 Aug; 8(2):111-8.
        View in: PubMed
      68. O'Shea CC, Choi S, McCormick F, Stokoe D. Adenovirus overrides cellular checkpoints for protein translation. Cell Cycle. 2005 Jul; 4(7):883-8.
        View in: PubMed
      69. O'Shea CC, Soria C, Bagus B, McCormick F. Heat shock phenocopies E1B-55K late functions and selectively sensitizes refractory tumor cells to ONYX-015 oncolytic viral therapy. Cancer Cell. 2005 Jul; 8(1):61-74.
        View in: PubMed
      70. Klein S, McCormick F, Levitzki A. Killing time for cancer cells. Nat Rev Cancer. 2005 Jul; 5(7):573-80.
        View in: PubMed
      71. He B, Reguart N, You L, Mazieres J, Xu Z, Lee AY, Mikami I, McCormick F, Jablons DM. Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations. Oncogene. 2005 Apr 21; 24(18):3054-8.
        View in: PubMed
      72. O'Shea C, Klupsch K, Choi S, Bagus B, Soria C, Shen J, McCormick F, Stokoe D. Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication. EMBO J. 2005 Mar 23; 24(6):1211-21.
        View in: PubMed
      73. Rodriguez-Viciana P, McCormick F. RalGDS comes of age. Cancer Cell. 2005 Mar; 7(3):205-6.
        View in: PubMed
      74. He B, Lee AY, Dadfarmay S, You L, Xu Z, Reguart N, Mazieres J, Mikami I, McCormick F, Jablons DM. Secreted frizzled-related protein 4 is silenced by hypermethylation and induces apoptosis in beta-catenin-deficient human mesothelioma cells. Cancer Res. 2005 Feb 1; 65(3):743-8.
        View in: PubMed
      75. Rodriguez-Viciana P, Tetsu O, Oda K, Okada J, Rauen K, McCormick F. Cancer targets in the Ras pathway. Cold Spring Harb Symp Quant Biol. 2005; 70:461-7.
        View in: PubMed
      76. Lee SH, McCormick F. Downregulation of Skp2 and p27/Kip1 synergistically induces apoptosis in T98G glioblastoma cells. J Mol Med (Berl). 2005 Apr; 83(4):296-307.
        View in: PubMed
      77. O'Shea CC, Johnson L, Bagus B, Choi S, Nicholas C, Shen A, Boyle L, Pandey K, Soria C, Kunich J, Shen Y, Habets G, Ginzinger D, McCormick F. Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity. Cancer Cell. 2004 Dec; 6(6):611-23.
        View in: PubMed
      78. Brandts CH, Bilanges B, Hare G, McCormick F, Stokoe D. Phosphorylation-independent stabilization of p27kip1 by the phosphoinositide 3-kinase pathway in glioblastoma cells. J Biol Chem. 2005 Jan 21; 280(3):2012-9.
        View in: PubMed
      79. Sheng T, Li C, Zhang X, Chi S, He N, Chen K, McCormick F, Gatalica Z, Xie J. Activation of the hedgehog pathway in advanced prostate cancer. Mol Cancer. 2004 Oct 13; 3:29.
        View in: PubMed
      80. Reguart N, He B, Xu Z, You L, Lee AY, Mazieres J, Mikami I, Batra S, Rosell R, McCormick F, Jablons DM. Cloning and characterization of the promoter of human Wnt inhibitory factor-1. Biochem Biophys Res Commun. 2004 Oct 8; 323(1):229-34.
        View in: PubMed
      81. Moule MG, Collins CH, McCormick F, Fried M. Role for PP2A in ARF signaling to p53. Proc Natl Acad Sci U S A. 2004 Sep 28; 101(39):14063-6.
        View in: PubMed
      82. Lee AY, He B, You L, Dadfarmay S, Xu Z, Mazieres J, Mikami I, McCormick F, Jablons DM. Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma. Oncogene. 2004 Aug 26; 23(39):6672-6.
        View in: PubMed
      83. You L, He B, Xu Z, Uematsu K, Mazieres J, Mikami I, Reguart N, Moody TW, Kitajewski J, McCormick F, Jablons DM. Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells. Oncogene. 2004 Aug 12; 23(36):6170-4.
        View in: PubMed
      84. You L, He B, Xu Z, Uematsu K, Mazieres J, Fujii N, Mikami I, Reguart N, McIntosh JK, Kashani-Sabet M, McCormick F, Jablons DM. An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth. Cancer Res. 2004 Aug 1; 64(15):5385-9.
        View in: PubMed
      85. Mazieres J, He B, You L, Xu Z, Lee AY, Mikami I, Reguart N, Rosell R, McCormick F, Jablons DM. Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer. Cancer Res. 2004 Jul 15; 64(14):4717-20.
        View in: PubMed
      86. Rodriguez-Viciana P, Sabatier C, McCormick F. Signaling specificity by Ras family GTPases is determined by the full spectrum of effectors they regulate. Mol Cell Biol. 2004 Jun; 24(11):4943-54.
        View in: PubMed
      87. You L, He B, Uematsu K, Xu Z, Mazieres J, Lee A, McCormick F, Jablons DM. Inhibition of Wnt-1 signaling induces apoptosis in beta-catenin-deficient mesothelioma cells. Cancer Res. 2004 May 15; 64(10):3474-8.
        View in: PubMed
      88. McCormick F. Cancer: survival pathways meet their end. Nature. 2004 Mar 18; 428(6980):267-9.
        View in: PubMed
      89. You L, He B, Xu Z, McCormick F, Jablons DM. Future directions: oncolytic viruses. Clin Lung Cancer. 2004 Jan; 5(4):226-30.
        View in: PubMed
      90. He B, You L, Uematsu K, Xu Z, Lee AY, Matsangou M, McCormick F, Jablons DM. A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells. Neoplasia. 2004 Jan-Feb; 6(1):7-14.
        View in: PubMed
      91. Timmerman LA, Grego-Bessa J, Raya A, Bertrán E, Pérez-Pomares JM, Díez J, Aranda S, Palomo S, McCormick F, Izpisúa-Belmonte JC, de la Pompa JL. Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation. Genes Dev. 2004 Jan 1; 18(1):99-115.
        View in: PubMed
      92. He B, You L, Uematsu K, Zang K, Xu Z, Lee AY, Costello JF, McCormick F, Jablons DM. SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer. Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24):14133-8.
        View in: PubMed
      93. Uematsu K, He B, You L, Xu Z, McCormick F, Jablons DM. Activation of the Wnt pathway in non small cell lung cancer: evidence of dishevelled overexpression. Oncogene. 2003 Oct 16; 22(46):7218-21.
        View in: PubMed
      94. Uematsu K, Kanazawa S, You L, He B, Xu Z, Li K, Peterlin BM, McCormick F, Jablons DM. Wnt pathway activation in mesothelioma: evidence of Dishevelled overexpression and transcriptional activity of beta-catenin. Cancer Res. 2003 Aug 1; 63(15):4547-51.
        View in: PubMed
      95. Albertson DG, Collins C, McCormick F, Gray JW. Chromosome aberrations in solid tumors. Nat Genet. 2003 Aug; 34(4):369-76.
        View in: PubMed
      96. McCormick F. Cancer-specific viruses and the development of ONYX-015. Cancer Biol Ther. 2003 Jul-Aug; 2(4 Suppl 1):S157-60.
        View in: PubMed
      97. Anders M, Christian C, McMahon M, McCormick F, Korn WM. Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells. Cancer Res. 2003 May 1; 63(9):2088-95.
        View in: PubMed
      98. Jensen RH, Tiirikainen M, You L, Ginzinger D, He B, Uematsu K, Xu Z, Treseler P, McCormick F, Jablons DM. Genomic alterations in human mesothelioma including high resolution mapping of common regions of DNA loss in chromosome arm 6q. Anticancer Res. 2003 May-Jun; 23(3B):2281-9.
        View in: PubMed
      99. Tetsu O, McCormick F. Proliferation of cancer cells despite CDK2 inhibition. Cancer Cell. 2003 Mar; 3(3):233-45.
        View in: PubMed
      100. He B, You L, Uematsu K, Matsangou M, Xu Z, He M, McCormick F, Jablons DM. Cloning and characterization of a functional promoter of the human SOCS-3 gene. Biochem Biophys Res Commun. 2003 Feb 7; 301(2):386-91.
        View in: PubMed
      101. Gump J, Stokoe D, McCormick F. Phosphorylation of p16INK4A correlates with Cdk4 association. J Biol Chem. 2003 Feb 28; 278(9):6619-22.
        View in: PubMed
      102. Yang CT, You L, Lin YC, Lin CL, Mccormick F, Jablons DM. A comparison analysis of anti-tumor efficacy of adenoviral gene replacement therapy (p14ARF and p16INK4A) in human mesothelioma cells. Anticancer Res. 2003 Jan-Feb; 23(1A):33-8.
        View in: PubMed
      103. Sherr CJ, McCormick F. The RB and p53 pathways in cancer. Cancer Cell. 2002 Aug; 2(2):103-12.
        View in: PubMed
      104. Xia C, Xu Z, Yuan X, Uematsu K, You L, Li K, Li L, McCormick F, Jablons DM. Induction of apoptosis in mesothelioma cells by antisurvivin oligonucleotides. Mol Cancer Ther. 2002 Jul; 1(9):687-94.
        View in: PubMed
      105. Rauen KA, Sudilovsky D, Le JL, Chew KL, Hann B, Weinberg V, Schmitt LD, McCormick F. Expression of the coxsackie adenovirus receptor in normal prostate and in primary and metastatic prostate carcinoma: potential relevance to gene therapy. Cancer Res. 2002 Jul 1; 62(13):3812-8.
        View in: PubMed
      106. Sabbatini P, McCormick F. MDMX inhibits the p300/CBP-mediated acetylation of p53. DNA Cell Biol. 2002 Jul; 21(7):519-25.
        View in: PubMed
      107. Johnson L, Shen A, Boyle L, Kunich J, Pandey K, Lemmon M, Hermiston T, Giedlin M, McCormick F, Fattaey A. Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents. Cancer Cell. 2002 May; 1(4):325-37.
        View in: PubMed
      108. Biederer C, Ries S, Brandts CH, McCormick F. Replication-selective viruses for cancer therapy. J Mol Med (Berl). 2002 Mar; 80(3):163-75.
        View in: PubMed
      109. McCormick F. Cancer gene therapy: fringe or cutting edge? Nat Rev Cancer. 2001 Nov; 1(2):130-41.
        View in: PubMed
      110. Yang CT, You L, Uematsu K, Yeh CC, McCormick F, Jablons DM. p14(ARF) modulates the cytolytic effect of ONYX-015 in mesothelioma cells with wild-type p53. Cancer Res. 2001 Aug 15; 61(16):5959-63.
        View in: PubMed
      111. Wakita K, McCormick F, Tetsu O. Method for screening ecdysone-inducible stable cell lines. Biotechniques. 2001 Aug; 31(2):414-8.
        View in: PubMed
      112. Xie J, Aszterbaum M, Zhang X, Bonifas JM, Zachary C, Epstein E, McCormick F. A role of PDGFRalpha in basal cell carcinoma proliferation. Proc Natl Acad Sci U S A. 2001 Jul 31; 98(16):9255-9.
        View in: PubMed
      113. Chen RH, McCormick F. Selective targeting to the hyperactive beta-catenin/T-cell factor pathway in colon cancer cells. Cancer Res. 2001 Jun 1; 61(11):4445-9.
        View in: PubMed
      114. Yount GL, Afshar G, Ries S, Korn M, Shalev N, Basila D, McCormick F, Haas-Kogan DA. Transcriptional activation of TRADD mediates p53-independent radiation-induced apoptosis of glioma cells. Oncogene. 2001 May 17; 20(22):2826-35.
        View in: PubMed
      115. Park JW, McCormick F. ErbB receptors and Ras: upstream, downstream? Cancer J. 2001 May-Jun; 7(3):178-80.
        View in: PubMed
      116. Wakita K, Tetsu O, McCormick F. A mammalian two-hybrid system for adenomatous polyposis coli-mutated colon cancer therapeutics. Cancer Res. 2001 Feb 1; 61(3):854-8.
        View in: PubMed
      117. McCormick F. ONYX-015 selectivity and the p14ARF pathway. Oncogene. 2000 Dec 27; 19(56):6670-2.
        View in: PubMed
      118. McCormick F. Small-molecule inhibitors of cell signaling. Curr Opin Biotechnol. 2000 Dec; 11(6):593-7.
        View in: PubMed
      119. McCormick F. Interactions between adenovirus proteins and the p53 pathway: the development of ONYX-015. Semin Cancer Biol. 2000 Dec; 10(6):453-9.
        View in: PubMed
      120. Ding VW, Chen RH, McCormick F. Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signaling. J Biol Chem. 2000 Oct 20; 275(42):32475-81.
        View in: PubMed
      121. Ries S, Biederer C, Woods D, Shifman O, Shirasawa S, Sasazuki T, McMahon M, Oren M, McCormick F. Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF. Cell. 2000 Oct 13; 103(2):321-30.
        View in: PubMed
      122. Ries SJ, Brandts CH, Chung AS, Biederer CH, Hann BC, Lipner EM, McCormick F, Korn WM. Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015). Nat Med. 2000 Oct; 6(10):1128-33.
        View in: PubMed
      123. Biederer CH, Ries SJ, Moser M, Florio M, Israel MA, McCormick F, Buettner R. The basic helix-loop-helix transcription factors myogenin and Id2 mediate specific induction of caveolin-3 gene expression during embryonic development. J Biol Chem. 2000 Aug 25; 275(34):26245-51.
        View in: PubMed
      124. Crompton AM, Foley LH, Wood A, Roscoe W, Stokoe D, McCormick F, Symons M, Bollag G. Regulation of Tiam1 nucleotide exchange activity by pleckstrin domain binding ligands. J Biol Chem. 2000 Aug 18; 275(33):25751-9.
        View in: PubMed
      125. Chen RH, Ding WV, McCormick F. Wnt signaling to beta-catenin involves two interactive components. Glycogen synthase kinase-3beta inhibition and activation of protein kinase C. J Biol Chem. 2000 Jun 9; 275(23):17894-9.
        View in: PubMed
      126. Yang CT, You L, Yeh CC, Chang JW, Zhang F, McCormick F, Jablons DM. Adenovirus-mediated p14(ARF) gene transfer in human mesothelioma cells. J Natl Cancer Inst. 2000 Apr 19; 92(8):636-41.
        View in: PubMed
      127. Tominaga T, Sahai E, Chardin P, McCormick F, Courtneidge SA, Alberts AS. Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling. Mol Cell. 2000 Jan; 5(1):13-25.
        View in: PubMed
      128. McCormick F. Signalling networks that cause cancer. Trends Cell Biol. 1999 Dec; 9(12):M53-6.
        View in: PubMed
      129. Srinivasan R, Benton E, McCormick F, Thomas H, Gullick WJ. Expression of the c-erbB-3/HER-3 and c-erbB-4/HER-4 growth factor receptors and their ligands, neuregulin-1 alpha, neuregulin-1 beta, and betacellulin, in normal endometrium and endometrial cancer. Clin Cancer Res. 1999 Oct; 5(10):2877-83.
        View in: PubMed
      130. Sabbatini P, McCormick F. Phosphoinositide 3-OH kinase (PI3K) and PKB/Akt delay the onset of p53-mediated, transcriptionally dependent apoptosis. J Biol Chem. 1999 Aug 20; 274(34):24263-9.
        View in: PubMed
      131. McCormick F. Cancer therapy based on p53. Cancer J Sci Am. 1999 May-Jun; 5(3):139-44.
        View in: PubMed
      132. Chardin P, McCormick F. Brefeldin A: the advantage of being uncompetitive. Cell. 1999 Apr 16; 97(2):153-5.
        View in: PubMed
      133. Tetsu O, McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature. 1999 Apr 1; 398(6726):422-6.
        View in: PubMed
      134. Lam CW, Xie J, To KF, Ng HK, Lee KC, Yuen NW, Lim PL, Chan LY, Tong SF, McCormick F. A frequent activated smoothened mutation in sporadic basal cell carcinomas. Oncogene. 1999 Jan 21; 18(3):833-6.
        View in: PubMed
      135. Kirn D, Hermiston T, McCormick F. ONYX-015: clinical data are encouraging. Nat Med. 1998 Dec; 4(12):1341-2.
        View in: PubMed
      136. McCormick F. Going for the GAP. Curr Biol. 1998 Sep 24; 8(19):R673-4.
        View in: PubMed
      137. Bellacosa A, Chan TO, Ahmed NN, Datta K, Malstrom S, Stokoe D, McCormick F, Feng J, Tsichlis P. Akt activation by growth factors is a multiple-step process: the role of the PH domain. Oncogene. 1998 Jul 23; 17(3):313-25.
        View in: PubMed
      138. McCormick F. Signal transduction. Why Ras needs Rho. Nature. 1998 Jul 16; 394(6690):220-1.
        View in: PubMed
      139. Stephens L, Anderson K, Stokoe D, Erdjument-Bromage H, Painter GF, Holmes AB, Gaffney PR, Reese CB, McCormick F, Tempst P, Coadwell J, Hawkins PT. Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B. Science. 1998 Jan 30; 279(5351):710-4.
        View in: PubMed
      140. Stokoe D, Stephens LR, Copeland T, Gaffney PR, Reese CB, Painter GF, Holmes AB, McCormick F, Hawkins PT. Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B. Science. 1997 Jul 25; 277(5325):567-70.
        View in: PubMed
      141. McCormick F. The superfamily of Ras-related GTPases. Jpn J Cancer Res. 1997 Jul; 88(7):inside front cover.
        View in: PubMed
      142. Qiu RG, Abo A, McCormick F, Symons M. Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation. Mol Cell Biol. 1997 Jun; 17(6):3449-58.
        View in: PubMed
      143. Heise C, Sampson-Johannes A, Williams A, McCormick F, Von Hoff DD, Kirn DH. ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents. Nat Med. 1997 Jun; 3(6):639-45.
        View in: PubMed
      144. Cook SJ, Beltman J, Cadwallader KA, McMahon M, McCormick F. Regulation of mitogen-activated protein kinase phosphatase-1 expression by extracellular signal-related kinase-dependent and Ca2+-dependent signal pathways in Rat-1 cells. J Biol Chem. 1997 May 16; 272(20):13309-19.
        View in: PubMed
      145. Stokoe D, McCormick F. Activation of c-Raf-1 by Ras and Src through different mechanisms: activation in vivo and in vitro. EMBO J. 1997 May 1; 16(9):2384-96.
        View in: PubMed
      146. Katz ME, McCormick F. Signal transduction from multiple Ras effectors. Curr Opin Genet Dev. 1997 Feb; 7(1):75-9.
        View in: PubMed
      147. Cadwallader K, Beltman J, McCormick F, Cook S. Differential regulation of extracellular signal-regulated protein kinase 1 and Jun N-terminal kinase 1 by Ca2+ and protein kinase C in endothelin-stimulated Rat-1 cells. Biochem J. 1997 Feb 1; 321 ( Pt 3):795-804.
        View in: PubMed
      148. Bollag G, Adler F, elMasry N, McCabe PC, Conner E, Thompson P, McCormick F, Shannon K. Biochemical characterization of a novel KRAS insertion mutation from a human leukemia. J Biol Chem. 1996 Dec 20; 271(51):32491-4.
        View in: PubMed
      149. Kirn DH, McCormick F. Replicating viruses as selective cancer therapeutics. Mol Med Today. 1996 Dec; 2(12):519-27.
        View in: PubMed
      150. Cook SJ, McCormick F. Kinetic and biochemical correlation between sustained p44ERK1 (44 kDa extracellular signal-regulated kinase 1) activation and lysophosphatidic acid-stimulated DNA synthesis in Rat-1 cells. Biochem J. 1996 Nov 15; 320 ( Pt 1):237-45.
        View in: PubMed
      151. Beltman J, McCormick F, Cook SJ. The selective protein kinase C inhibitor, Ro-31-8220, inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) expression, induces c-Jun expression, and activates Jun N-terminal kinase. J Biol Chem. 1996 Oct 25; 271(43):27018-24.
        View in: PubMed
      152. Bischoff JR, Kirn DH, Williams A, Heise C, Horn S, Muna M, Ng L, Nye JA, Sampson-Johannes A, Fattaey A, McCormick F. An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science. 1996 Oct 18; 274(5286):373-6.
        View in: PubMed
      153. O'Hagan RC, Tozer RG, Symons M, McCormick F, Hassell JA. The activity of the Ets transcription factor PEA3 is regulated by two distinct MAPK cascades. Oncogene. 1996 Sep 19; 13(6):1323-33.
        View in: PubMed
      154. Hartsough MT, Frey RS, Zipfel PA, Buard A, Cook SJ, McCormick F, Mulder KM. Altered transforming growth factor signaling in epithelial cells when ras activation is blocked. J Biol Chem. 1996 Sep 13; 271(37):22368-75.
        View in: PubMed
      155. Oliff A, Gibbs JB, McCormick F. New molecular targets for cancer therapy. Sci Am. 1996 Sep; 275(3):144-9.
        View in: PubMed
      156. McCormick F. Ras biology in atomic detail. Nat Struct Biol. 1996 Aug; 3(8):653-5.
        View in: PubMed
      157. McCormick F, Wittinghofer A. Interactions between Ras proteins and their effectors. Curr Opin Biotechnol. 1996 Aug; 7(4):449-56.
        View in: PubMed
      158. Medema JP, Pronk GJ, de Vries-Smits AM, Clark R, McCormick F, Bos JL. Insulin-induced tyrosine phosphorylation of a M(r) 70,000 protein revealed by association with the Src homology 2 (SH2) and SH3 domains of p120GAP and Grb2. Cell Growth Differ. 1996 Apr; 7(4):543-50.
        View in: PubMed
      159. Porfiri E, McCormick F. Regulation of epidermal growth factor receptor signaling by phosphorylation of the ras exchange factor hSOS1. J Biol Chem. 1996 Mar 8; 271(10):5871-7.
        View in: PubMed
      160. Symons M, Derry JM, Karlak B, Jiang S, Lemahieu V, Mccormick F, Francke U, Abo A. Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization. Cell. 1996 Mar 8; 84(5):723-34.
        View in: PubMed
      161. Bollag G, Clapp DW, Shih S, Adler F, Zhang YY, Thompson P, Lange BJ, Freedman MH, McCormick F, Jacks T, Shannon K. Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells. Nat Genet. 1996 Feb; 12(2):144-8.
        View in: PubMed
      162. Lock P, Fumagalli S, Polakis P, McCormick F, Courtneidge SA. The human p62 cDNA encodes Sam68 and not the RasGAP-associated p62 protein. Cell. 1996 Jan 12; 84(1):23-4.
        View in: PubMed
      163. Qiu RG, Chen J, McCormick F, Symons M. A role for Rho in Ras transformation. Proc Natl Acad Sci U S A. 1995 Dec 5; 92(25):11781-5.
        View in: PubMed
      164. McCormick F. Ras-related proteins in signal transduction and growth control. Mol Reprod Dev. 1995 Dec; 42(4):500-6.
        View in: PubMed
      165. Braselmann S, McCormick F. Bcr and Raf form a complex in vivo via 14-3-3 proteins. EMBO J. 1995 Oct 2; 14(19):4839-48.
        View in: PubMed
      166. Martin GA, Bollag G, McCormick F, Abo A. A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20. EMBO J. 1995 Sep 1; 14(17):4385.
        View in: PubMed
      167. Bryant SS, Briggs S, Smithgall TE, Martin GA, McCormick F, Chang JH, Parsons SJ, Jove R. Two SH2 domains of p120 Ras GTPase-activating protein bind synergistically to tyrosine phosphorylated p190 Rho GTPase-activating protein. J Biol Chem. 1995 Jul 28; 270(30):17947-52.
        View in: PubMed
      168. Peppelenbosch MP, Qiu RG, de Vries-Smits AM, Tertoolen LG, de Laat SW, McCormick F, Hall A, Symons MH, Bos JL. Rac mediates growth factor-induced arachidonic acid release. Cell. 1995 Jun 16; 81(6):849-56.
        View in: PubMed
      169. Nassar N, Horn G, Herrmann C, Scherer A, McCormick F, Wittinghofer A. The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue. Nature. 1995 Jun 15; 375(6532):554-60.
        View in: PubMed
      170. Martin GA, Bollag G, McCormick F, Abo A. A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20. EMBO J. 1995 May 1; 14(9):1970-8.
        View in: PubMed
      171. Qiu RG, Chen J, Kirn D, McCormick F, Symons M. An essential role for Rac in Ras transformation. Nature. 1995 Mar 30; 374(6521):457-9.
        View in: PubMed
      172. McCormick F. Ras signaling and NF1. Curr Opin Genet Dev. 1995 Feb; 5(1):51-5.
        View in: PubMed
      173. Spaargaren M, Bischoff JR, McCormick F. Signal transduction by Ras-like GTPases: a potential target for anticancer drugs. Gene Expr. 1995; 4(6):345-56.
        View in: PubMed
      174. Bollag G, McCormick F. Intrinsic and GTPase-activating protein-stimulated Ras GTPase assays. Methods Enzymol. 1995; 255:161-70.
        View in: PubMed
      175. Bollag G, McCormick F. Purification of recombinant Ras GTPase-activating proteins. Methods Enzymol. 1995; 255:21-30.
        View in: PubMed
      176. McCormick F. Raf: the holy grail of Ras biology? Trends Cell Biol. 1994 Oct; 4(10):347-50.
        View in: PubMed
      177. Freed E, Symons M, Macdonald SG, McCormick F, Ruggieri R. Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation. Science. 1994 Sep 16; 265(5179):1713-6.
        View in: PubMed
      178. McCormick F, Myers P. From genetics to chemistry: tumor suppressor genes and drug discovery. Chem Biol. 1994 Sep; 1(1):7-9.
        View in: PubMed
      179. Cook S, McCormick F. Ras blooms on sterile ground. Nature. 1994 Jun 2; 369(6479):361-2.
        View in: PubMed
      180. Spaargaren M, Martin GA, McCormick F, Fernandez-Sarabia MJ, Bischoff JR. The Ras-related protein R-ras interacts directly with Raf-1 in a GTP-dependent manner. Biochem J. 1994 Jun 1; 300 ( Pt 2):303-7.
        View in: PubMed
      181. Shannon KM, O'Connell P, Martin GA, Paderanga D, Olson K, Dinndorf P, McCormick F. Loss of the normal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders. N Engl J Med. 1994 Mar 3; 330(9):597-601.
        View in: PubMed
      182. Burgering BM, Freed E, van der Voorn L, McCormick F, Bos JL. Platelet-derived growth factor-induced p21ras-mediated signaling is independent of platelet-derived growth factor receptor interaction with GTPase-activating protein or phosphatidylinositol-3-kinase. Cell Growth Differ. 1994 Mar; 5(3):341-7.
        View in: PubMed
      183. Ruggieri R, Macdonald SG, Callow M, McCormick F. Raf-1 interferes with Ras and Rap1A effector functions in yeast. Mol Biol Cell. 1994 Feb; 5(2):173-81.
        View in: PubMed
      184. McCormick F. Activators and effectors of ras p21 proteins. Curr Opin Genet Dev. 1994 Feb; 4(1):71-6.
        View in: PubMed
      185. Xu N, McCormick F, Gutkind JS. The non-catalytic domain of ras-GAP inhibits transformation induced by G protein coupled receptors. Oncogene. 1994 Feb; 9(2):597-601.
        View in: PubMed
      186. Sato KY, Polakis PG, Haubruck H, Fasching CL, McCormick F, Stanbridge EJ. Analysis of the tumor suppressor activity of the K-rev-1 gene in human tumor cell lines. Cancer Res. 1994 Jan 15; 54(2):552-9.
        View in: PubMed
      187. Weiss J, Rubinfeld B, Polakis PG, McCormick F, Cavenee WK, Arden KC. The RAP1GA1 locus for human Rap1-GTPase activating protein 1 maps to chromosome 1p36.1-->p35. Cytogenet Cell Genet. 1994; 66(1):18-21.
        View in: PubMed
      188. Mitsudomi T, Friedman E, Gejman PV, McCormick F, Gazdar AF. Genetic analysis of the catalytic domain of the GAP gene in human lung cancer cell lines. Hum Genet. 1994 Jan; 93(1):27-31.
        View in: PubMed
      189. Freed E, McCormick F, Ruggieri R. Proteins of the 14-3-3 family associate with Raf and contribute to its activation. Cold Spring Harb Symp Quant Biol. 1994; 59:187-93.
        View in: PubMed
      190. Boguski MS, McCormick F. Proteins regulating Ras and its relatives. Nature. 1993 Dec 16; 366(6456):643-54.
        View in: PubMed
      191. Lübbert M, Oster W, Knopf HP, McCormick F, Mertelsmann R, Herrmann F. N-RAS gene activation in acute myeloid leukemia: association with expression of interleukin-6. Leukemia. 1993 Dec; 7(12):1948-54.
        View in: PubMed
      192. Cook SJ, McCormick F. Inhibition by cAMP of Ras-dependent activation of Raf. Science. 1993 Nov 12; 262(5136):1069-72.
        View in: PubMed
      193. Friedman E, Gejman PV, Martin GA, McCormick F. Nonsense mutations in the C-terminal SH2 region of the GTPase activating protein (GAP) gene in human tumours. Nat Genet. 1993 Nov; 5(3):242-7.
        View in: PubMed
      194. Macdonald SG, Crews CM, Wu L, Driller J, Clark R, Erikson RL, McCormick F. Reconstitution of the Raf-1-MEK-ERK signal transduction pathway in vitro. Mol Cell Biol. 1993 Nov; 13(11):6615-20.
        View in: PubMed
      195. Cook SJ, Rubinfeld B, Albert I, McCormick F. RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts. EMBO J. 1993 Sep; 12(9):3475-85.
        View in: PubMed
      196. Polakis P, McCormick F. Structural requirements for the interaction of p21ras with GAP, exchange factors, and its biological effector target. J Biol Chem. 1993 May 5; 268(13):9157-60.
        View in: PubMed
      197. Bollag G, McCormick F, Clark R. Characterization of full-length neurofibromin: tubulin inhibits Ras GAP activity. EMBO J. 1993 May; 12(5):1923-7.
        View in: PubMed
      198. al-Alawi N, Xu G, White R, Clark R, McCormick F, Feramisco JR. Differential regulation of cellular activities by GTPase-activating protein and NF1. Mol Cell Biol. 1993 Apr; 13(4):2497-503.
        View in: PubMed
      199. Gold MR, Crowley MT, Martin GA, McCormick F, DeFranco AL. Targets of B lymphocyte antigen receptor signal transduction include the p21ras GTPase-activating protein (GAP) and two GAP-associated proteins. J Immunol. 1993 Jan 15; 150(2):377-86.
        View in: PubMed
      200. McCormick F. The GTPase superfamily. Introduction. Ciba Found Symp. 1993; 176:1-5.
        View in: PubMed
      201. Filvaroff E, Calautti E, McCormick F, Dotto GP. Specific changes of Ras GTPase-activating protein (GAP) and a GAP-associated p62 protein during calcium-induced keratinocyte differentiation. Mol Cell Biol. 1992 Dec; 12(12):5319-28.
        View in: PubMed
      202. Rubinfeld B, Crosier WJ, Albert I, Conroy L, Clark R, McCormick F, Polakis P. Localization of the rap1GAP catalytic domain and sites of phosphorylation by mutational analysis. Mol Cell Biol. 1992 Oct; 12(10):4634-42.
        View in: PubMed
      203. McCabe PC, Haubruck H, Polakis P, McCormick F, Innis MA. Functional interaction between p21rap1A and components of the budding pathway in Saccharomyces cerevisiae. Mol Cell Biol. 1992 Sep; 12(9):4084-92.
        View in: PubMed
      204. Medema RH, de Laat WL, Martin GA, McCormick F, Bos JL. GTPase-activating protein SH2-SH3 domains induce gene expression in a Ras-dependent fashion. Mol Cell Biol. 1992 Aug; 12(8):3425-30.
        View in: PubMed
      205. Bollag G, McCormick F. GTPase activating proteins. Semin Cancer Biol. 1992 Aug; 3(4):199-208.
        View in: PubMed
      206. Goretzki PE, Lyons J, Stacy-Phipps S, Rosenau W, Demeure M, Clark OH, McCormick F, Röher HD, Bourne HR. Mutational activation of RAS and GSP oncogenes in differentiated thyroid cancer and their biological implications. World J Surg. 1992 Jul-Aug; 16(4):576-81; discussion 581-2.
        View in: PubMed
      207. Polakis P, Rubinfeld B, McCormick F. Phosphorylation of rap1GAP in vivo and by cAMP-dependent kinase and the cell cycle p34cdc2 kinase in vitro. J Biol Chem. 1992 May 25; 267(15):10780-5.
        View in: PubMed
      208. Wong G, Müller O, Clark R, Conroy L, Moran MF, Polakis P, McCormick F. Molecular cloning and nucleic acid binding properties of the GAP-associated tyrosine phosphoprotein p62. Cell. 1992 May 1; 69(3):551-8.
        View in: PubMed
      209. Fantl WJ, Escobedo JA, Martin GA, Turck CW, del Rosario M, McCormick F, Williams LT. Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways. Cell. 1992 May 1; 69(3):413-23.
        View in: PubMed
      210. McCormick F. Coupling of ras p21 signalling and GTP hydrolysis by GTPase activating proteins. Philos Trans R Soc Lond B Biol Sci. 1992 Apr 29; 336(1276):43-7; discussion 47-8.
        View in: PubMed
      211. Bollag G, McCormick F. Ras regulation. NF is enough of GAP. Nature. 1992 Apr 23; 356(6371):663-4.
        View in: PubMed
      212. Cichowski K, McCormick F, Brugge JS. p21rasGAP association with Fyn, Lyn, and Yes in thrombin-activated platelets. J Biol Chem. 1992 Mar 15; 267(8):5025-8.
        View in: PubMed
      213. Lübbert M, Mirro J, Kitchingman G, McCormick F, Mertelsmann R, Herrmann F, Koeffler HP. Prevalence of N-ras mutations in children with myelodysplastic syndromes and acute myeloid leukemia. Oncogene. 1992 Feb; 7(2):263-8.
        View in: PubMed
      214. Pronk GJ, Polakis P, Wong G, de Vries-Smits AM, Bos JL, McCormick F. Association of a tyrosine kinase activity with GAP complexes in v-src transformed fibroblasts. Oncogene. 1992 Feb; 7(2):389-94.
        View in: PubMed
      215. Martin GA, Yatani A, Clark R, Conroy L, Polakis P, Brown AM, McCormick F. GAP domains responsible for ras p21-dependent inhibition of muscarinic atrial K+ channel currents. Science. 1992 Jan 10; 255(5041):192-4.
        View in: PubMed
      216. Zhang K, Papageorge AG, Martin P, Vass WC, Olah Z, Polakis PG, McCormick F, Lowy DR. Heterogeneous amino acids in Ras and Rap1A specifying sensitivity to GAP proteins. Science. 1991 Dec 13; 254(5038):1630-4.
        View in: PubMed
      217. Haubruck H, McCormick F. Ras p21: effects and regulation. Biochim Biophys Acta. 1991 Dec 10; 1072(2-3):215-29.
        View in: PubMed
      218. Dominguez I, Marshall MS, Gibbs JB, García de Herreros A, Cornet ME, Graziani G, Diaz-Meco MT, Johansen T, McCormick F, Moscat J. Role of GTPase activating protein in mitogenic signalling through phosphatidylcholine-hydrolysing phospholipase C. EMBO J. 1991 Nov; 10(11):3215-20.
        View in: PubMed
      219. Ruggieri R, McCormick F. Ras and the awd couple. Nature. 1991 Oct 3; 353(6343):390-1.
        View in: PubMed
      220. Pendergast AM, Muller AJ, Havlik MH, Clark R, McCormick F, Witte ON. Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor. Proc Natl Acad Sci U S A. 1991 Jul 1; 88(13):5927-31.
        View in: PubMed
      221. Rubinfeld B, Wong G, Bekesi E, Wood A, Heimer E, McCormick F, Polakis P. A synthetic peptide corresponding to a sequence in the GTPase activating protein inhibits p21ras stimulation and promotes guanine nucleotide exchange. Int J Pept Protein Res. 1991 Jul; 38(1):47-53.
        View in: PubMed
      222. Rubinfeld B, Munemitsu S, Clark R, Conroy L, Watt K, Crosier WJ, McCormick F, Polakis P. Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1. Cell. 1991 Jun 14; 65(6):1033-42.
        View in: PubMed
      223. Bollag G, McCormick F. Differential regulation of rasGAP and neurofibromatosis gene product activities. Nature. 1991 Jun 13; 351(6327):576-9.
        View in: PubMed
      224. McCormick F. GTP-binding proteins as oncogenes in human tumors. Environ Health Perspect. 1991 Jun; 93:17-8.
        View in: PubMed
      225. Burgering BM, Medema RH, Maassen JA, van de Wetering ML, van der Eb AJ, McCormick F, Bos JL. Insulin stimulation of gene expression mediated by p21ras activation. EMBO J. 1991 May; 10(5):1103-9.
        View in: PubMed
      226. Han JW, McCormick F, Macara IG. Regulation of Ras-GAP and the neurofibromatosis-1 gene product by eicosanoids. Science. 1991 Apr 26; 252(5005):576-9.
        View in: PubMed
      227. Moran MF, Polakis P, McCormick F, Pawson T, Ellis C. Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein. Mol Cell Biol. 1991 Apr; 11(4):1804-12.
        View in: PubMed
      228. Buss JE, Quilliam LA, Kato K, Casey PJ, Solski PA, Wong G, Clark R, McCormick F, Bokoch GM, Der CJ. The COOH-terminal domain of the Rap1A (Krev-1) protein is isoprenylated and supports transformation by an H-Ras:Rap1A chimeric protein. Mol Cell Biol. 1991 Mar; 11(3):1523-30.
        View in: PubMed
      229. Bourne HR, Sanders DA, McCormick F. The GTPase superfamily: conserved structure and molecular mechanism. Nature. 1991 Jan 10; 349(6305):117-27.
        View in: PubMed
      230. Polakis PG, Rubinfeld B, Evans T, McCormick F. Purification of a plasma membrane-associated GTPase-activating protein specific for rap1/Krev-1 from HL60 cells. Proc Natl Acad Sci U S A. 1991 Jan 1; 88(1):239-43.
        View in: PubMed
      231. Bollag G, McCormick F. Regulators and effectors of ras proteins. Annu Rev Cell Biol. 1991; 7:601-32.
        View in: PubMed
      232. McCormick F, Martin GA, Clark R, Bollag G, Polakis P. Regulation of ras p21 by GTPase activating proteins. Cold Spring Harb Symp Quant Biol. 1991; 56:237-41.
        View in: PubMed
      233. Halenbeck R, Crosier WJ, Clark R, McCormick F, Koths K. Purification, characterization, and western blot analysis of human GTPase-activating protein from native and recombinant sources. J Biol Chem. 1990 Dec 15; 265(35):21922-8.
        View in: PubMed
      234. Landis CA, Harsh G, Lyons J, Davis RL, McCormick F, Bourne HR. Clinical characteristics of acromegalic patients whose pituitary tumors contain mutant Gs protein. J Clin Endocrinol Metab. 1990 Dec; 71(6):1416-20.
        View in: PubMed
      235. Bourne HR, Sanders DA, McCormick F. The GTPase superfamily: a conserved switch for diverse cell functions. Nature. 1990 Nov 8; 348(6297):125-32.
        View in: PubMed
      236. Paquette RL, Berenson J, Lichtenstein A, McCormick F, Koeffler HP. Oncogenes in multiple myeloma: point mutation of N-ras. Oncogene. 1990 Nov; 5(11):1659-63.
        View in: PubMed
      237. Munemitsu S, Innis MA, Clark R, McCormick F, Ullrich A, Polakis P. Molecular cloning and expression of a G25K cDNA, the human homolog of the yeast cell cycle gene CDC42. Mol Cell Biol. 1990 Nov; 10(11):5977-82.
        View in: PubMed
      238. McCormick F. The world according to GAP. Oncogene. 1990 Sep; 5(9):1281-3.
        View in: PubMed
      239. Zhang K, DeClue JE, Vass WC, Papageorge AG, McCormick F, Lowy DR. Suppression of c-ras transformation by GTPase-activating protein. Nature. 1990 Aug 23; 346(6286):754-6.
        View in: PubMed
      240. Frech M, John J, Pizon V, Chardin P, Tavitian A, Clark R, McCormick F, Wittinghofer A. Inhibition of GTPase activating protein stimulation of Ras-p21 GTPase by the Krev-1 gene product. Science. 1990 Jul 13; 249(4965):169-71.
        View in: PubMed
      241. Quilliam LA, Der CJ, Clark R, O'Rourke EC, Zhang K, McCormick F, Bokoch GM. Biochemical characterization of baculovirus-expressed rap1A/Krev-1 and its regulation by GTPase-activating proteins. Mol Cell Biol. 1990 Jun; 10(6):2901-8.
        View in: PubMed
      242. Yatani A, Okabe K, Polakis P, Halenbeck R, McCormick F, Brown AM. ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K+ channels. Cell. 1990 Jun 1; 61(5):769-76.
        View in: PubMed
      243. Kaplan DR, Morrison DK, Wong G, McCormick F, Williams LT. PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex. Cell. 1990 Apr 6; 61(1):125-33.
        View in: PubMed
      244. Lübbert M, Jonas D, Miller CW, Herrmann F, Mertelsmann R, McCormick F, Koeffler HP. Retrospective analysis of ras gene activation in myeloid leukemic cells. Oncogene. 1990 Apr; 5(4):583-7.
        View in: PubMed
      245. McCormick F. GTP binding and growth control. Curr Opin Cell Biol. 1990 Apr; 2(2):181-4.
        View in: PubMed
      246. Lübbert M, Mirro J, Miller CW, Kahan J, Isaac G, Kitchingman G, Mertelsmann R, Herrmann F, McCormick F, Koeffler HP. N-ras gene point mutations in childhood acute lymphocytic leukemia correlate with a poor prognosis. Blood. 1990 Mar 1; 75(5):1163-9.
        View in: PubMed
      247. Carter G, Hughes DC, Clark RE, McCormick F, Jacobs A, Whittaker JA, Padua RA. RAS mutations in patients following cytotoxic therapy for lymphoma. Oncogene. 1990 Mar; 5(3):411-6.
        View in: PubMed
      248. Ellis C, Moran M, McCormick F, Pawson T. Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases. Nature. 1990 Jan 25; 343(6256):377-81.
        View in: PubMed
      249. McCormick F. GAP as ras effector or negative regulator? Mol Carcinog. 1990; 3(4):185-7.
        View in: PubMed
      250. Ballester R, Michaeli T, Ferguson K, Xu HP, McCormick F, Wigler M. Genetic analysis of mammalian GAP expressed in yeast. Cell. 1989 Nov 17; 59(4):681-6.
        View in: PubMed
      251. Valverius EM, Walker-Jones D, Bates SE, Stampfer MR, Clark R, McCormick F, Dickson RB, Lippman ME. Production of and responsiveness to transforming growth factor-beta in normal and oncogene-transformed human mammary epithelial cells. Cancer Res. 1989 Nov 15; 49(22):6269-74.
        View in: PubMed
      252. Burk SC, Papastavros MZ, McCormick F, Redfield AG. Identification of resonances from an oncogenic activating locus of human N-RAS-encoded p21 protein using isotope-edited NMR. Proc Natl Acad Sci U S A. 1989 Feb; 86(3):817-20.
        View in: PubMed
      253. McCormick F. ras GTPase activating protein: signal transmitter and signal terminator. Cell. 1989 Jan 13; 56(1):5-8.
        View in: PubMed
      254. Neri A, Knowles DM, Greco A, McCormick F, Dalla-Favera R. Analysis of RAS oncogene mutations in human lymphoid malignancies. Proc Natl Acad Sci U S A. 1988 Dec; 85(23):9268-72.
        View in: PubMed
      255. Clark R, Stampfer MR, Milley R, O'Rourke E, Walen KH, Kriegler M, Kopplin J, McCormick F. Transformation of human mammary epithelial cells by oncogenic retroviruses. Cancer Res. 1988 Aug 15; 48(16):4689-94.
        View in: PubMed
      256. Padua RA, Carter G, Hughes D, Gow J, Farr C, Oscier D, McCormick F, Jacobs A. RAS mutations in myelodysplasia detected by amplification, oligonucleotide hybridization, and transformation. Leukemia. 1988 Aug; 2(8):503-10.
        View in: PubMed
      257. Adari H, Lowy DR, Willumsen BM, Der CJ, McCormick F. Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain. Science. 1988 Apr 22; 240(4851):518-21.
        View in: PubMed
      258. Creasey AA, Vitt CR, Herst C, O'Rourke E, Doyle L, Innis MA, McCabe PC, McCormick F, Milley R, Lin LS, et al. Functional properties of proteins coded by three human alpha-interferon genes and a pseudogene. Cancer Res. 1988 Apr 1; 48(7):1763-70.
        View in: PubMed
      259. McCormick F, Adari H, Trahey M, Halenbeck R, Koths K, Martin GA, Crosier WJ, Watt K, Rubinfeld B, Wong G. Interaction of ras p21 proteins with GTPase activating protein. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 2:849-54.
        View in: PubMed
      260. Trahey M, McCormick F. A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants. Science. 1987 Oct 23; 238(4826):542-5.
        View in: PubMed
      261. Trahey M, Milley RJ, Cole GE, Innis M, Paterson H, Marshall CJ, Hall A, McCormick F. Biochemical and biological properties of the human N-ras p21 protein. Mol Cell Biol. 1987 Jan; 7(1):541-4.
        View in: PubMed
      262. Wong G, Arnheim N, Clark R, McCabe P, Innis M, Aldwin L, Nitecki D, McCormick F. Detection of activated Mr 21,000 protein, the product of ras oncogenes, using antibodies with specificity for amino acid 12. Cancer Res. 1986 Dec; 46(12 Pt 1):6029-33.
        View in: PubMed
      263. McCormick F, Levenson C, Cole G, Innis M, Clark R. Genetic and biochemical analysis of ras p21 structure. Symp Fundam Cancer Res. 1986; 39:137-42.
        View in: PubMed
      264. Clark R, Wong G, Arnheim N, Nitecki D, McCormick F. Antibodies specific for amino acid 12 of the ras oncogene product inhibit GTP binding. Proc Natl Acad Sci U S A. 1985 Aug; 82(16):5280-4.
        View in: PubMed
      265. Feramisco JR, Clark R, Wong G, Arnheim N, Milley R, McCormick F. Transient reversion of ras oncogene-induced cell transformation by antibodies specific for amino acid 12 of ras protein. Nature. 1985 Apr 18-24; 314(6012):639-42.
        View in: PubMed
      266. McCormick F, Trahey M, Innis M, Dieckmann B, Ringold G. Inducible expression of amplified human beta interferon genes in CHO cells. Mol Cell Biol. 1984 Jan; 4(1):166-72.
        View in: PubMed
      267. McCormick F, Harlow E. Association of a murine 53,000-dalton phosphoprotein with simian virus 40 large-T antigen in transformed cells. J Virol. 1980 Apr; 34(1):213-24.
        View in: PubMed
      268. McCormick F, Chaudry F, Harvey R, Smith R, Rigby PW, Paucha E, Smith AE. T antigens of SV40-transformed cells. Cold Spring Harb Symp Quant Biol. 1980; 44 Pt 1,:171-8.
        View in: PubMed
      Frank's Networks
      Related Concepts
      Derived automatically from this person's publications.
      _
      Co-Authors
      People in Profiles who have published with this person.
      _
      Related Authors
      People who share related concepts with this person.
      _
      Back to TOP