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    Natalia Jura, PhD

    TitleAssistant Professor
    SchoolUCSF School of Medicine
    DepartmentCardiovascular Research Inst
    Address555 Mission Bay Blvd South
    San Francisco CA 94158
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Kung JE, Jura N. Structural Basis for the Non-catalytic Functions of Protein Kinases. Structure. 2016 Jan 5; 24(1):7-24. PMID: 26745528.
        View in: PubMed
      2. Kovacs E, Das R, Wang Q, Collier TS, Cantor A, Huang Y, Wong K, Mirza A, Barros T, Grob P, Jura N, Bose R, Kuriyan J. Analysis of the Role of the C-Terminal Tail in the Regulation of the Epidermal Growth Factor Receptor. Mol Cell Biol. 2015 Sep 1; 35(17):3083-102. PMID: 26124280; PMCID: PMC4525312 [Available on 03/01/16].
      3. Littlefield P, Liu L, Mysore V, Shan Y, Shaw DE, Jura N. Structural analysis of the EGFR/HER3 heterodimer reveals the molecular basis for activating HER3 mutations. Sci Signal. 2014 Dec 2; 7(354):ra114. PMID: 25468994; PMCID: PMC4492339 [Available on 12/02/15].
      4. Littlefield P, Moasser MM, Jura N. An ATP-competitive inhibitor modulates the allosteric function of the HER3 pseudokinase. Chem Biol. 2014 Apr 24; 21(4):453-8. PMID: 24656791; PMCID: PMC4018233.
      5. Murphy JM, Zhang Q, Young SN, Reese ML, Bailey FP, Eyers PA, Ungureanu D, Hammaren H, Silvennoinen O, Varghese LN, Chen K, Tripaydonis A, Jura N, Fukuda K, Qin J, Nimchuk Z, Mudgett MB, Elowe S, Gee CL, Liu L, Daly RJ, Manning G, Babon JJ, Lucet IS. A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties. Biochem J. 2014 Jan 15; 457(2):323-34. PMID: 24107129.
        View in: PubMed
      6. Fan QW, Cheng CK, Gustafson WC, Charron E, Zipper P, Wong RA, Chen J, Lau J, Knobbe-Thomsen C, Weller M, Jura N, Reifenberger G, Shokat KM, Weiss WA. EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma. Cancer Cell. 2013 Oct 14; 24(4):438-49. PMID: 24135280; PMCID: PMC3819146.
      7. Littlefield P, Jura N. EGFR lung cancer mutants get specialized. Proc Natl Acad Sci U S A. 2013 Sep 17; 110(38):15169-70. PMID: 24023066; PMCID: PMC3780895.
      8. Jura N, Zhang X, Endres NF, Seeliger MA, Schindler T, Kuriyan J. Catalytic control in the EGF receptor and its connection to general kinase regulatory mechanisms. Mol Cell. 2011 Apr 8; 42(1):9-22. PMID: 21474065; PMCID: PMC3175429.
      9. Jura N, Shan Y, Cao X, Shaw DE, Kuriyan J. Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3. Proc Natl Acad Sci U S A. 2009 Dec 22; 106(51):21608-13. PMID: 20007378.
        View in: PubMed
      10. Jura N, Endres NF, Engel K, Deindl S, Das R, Lamers MH, Wemmer DE, Zhang X, Kuriyan J. Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment. Cell. 2009 Jun 26; 137(7):1293-307. PMID: 19563760; PMCID: PMC2814540.
      11. Zhang X, Pickin KA, Bose R, Jura N, Cole PA, Kuriyan J. Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface. Nature. 2007 Nov 29; 450(7170):741-4. PMID: 18046415; PMCID: PMC3561764.
      12. Jura N, Bar-Sagi D. Mapping cellular routes of Ras: a ubiquitin trail. Cell Cycle. 2006 Dec; 5(23):2744-7. PMID: 17172849.
        View in: PubMed
      13. Archer H, Jura N, Keller J, Jacobson M, Bar-Sagi D. A mouse model of hereditary pancreatitis generated by transgenic expression of R122H trypsinogen. Gastroenterology. 2006 Dec; 131(6):1844-55. PMID: 17087933.
        View in: PubMed
      14. Jura N, Scotto-Lavino E, Sobczyk A, Bar-Sagi D. Differential modification of Ras proteins by ubiquitination. Mol Cell. 2006 Mar 3; 21(5):679-87. PMID: 16507365.
        View in: PubMed
      15. Kilarski WW, Jura N, Gerwins P. An ex vivo model for functional studies of myofibroblasts. Lab Invest. 2005 May; 85(5):643-54. PMID: 15723087.
        View in: PubMed
      16. Mezyk-Kopec R, Bzowska M, Potempa J, Bzowska M, Jura N, Sroka A, Black RA, Bereta J. Inactivation of membrane tumor necrosis factor alpha by gingipains from Porphyromonas gingivalis. Infect Immun. 2005 Mar; 73(3):1506-14. PMID: 15731048; PMCID: PMC1064957.
      17. Jura N, Archer H, Bar-Sagi D. Chronic pancreatitis, pancreatic adenocarcinoma and the black box in-between. Cell Res. 2005 Jan; 15(1):72-7. PMID: 15686632.
        View in: PubMed
      18. Bzowska M, Jura N, Lassak A, Black RA, Bereta J. Tumour necrosis factor-alpha stimulates expression of TNF-alpha converting enzyme in endothelial cells. Eur J Biochem. 2004 Jul; 271(13):2808-20. PMID: 15206946.
        View in: PubMed
      19. Kilarski WW, Jura N, Gerwins P. Inactivation of Src family kinases inhibits angiogenesis in vivo: implications for a mechanism involving organization of the actin cytoskeleton. Exp Cell Res. 2003 Nov 15; 291(1):70-82. PMID: 14597409.
        View in: PubMed
      20. Hall AB, Jura N, DaSilva J, Jang YJ, Gong D, Bar-Sagi D. hSpry2 is targeted to the ubiquitin-dependent proteasome pathway by c-Cbl. Curr Biol. 2003 Feb 18; 13(4):308-14. PMID: 12593796.
        View in: PubMed
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