Qizhi Tang, PhD
|School||UCSF School of Medicine|
|Address||513 Parnassus Ave|
San Francisco CA 94143
|University of California, San Francisco||Postdoctoral Studies||Graduate Division||2002|
|Univeristy of Chicago||Postdoctoral Studies||Immunology||2000|
|University of Illinios, Chicago||PhD||Microbiology and Immunology||1996|
|University of South Alabama||Graduate School||Microbiology and Immunology||1991|
|Perkin Union Medical College||Medical School||Medcine||1989|
Dr. Tang investigates the immune system’s self-control mechanisms to prevent autoimmune diseases. These mechanisms are broken in autoimmune patients and therapies that restore these mechanisms can reverse tissue damages in autoimmune diseases. Additionally, these mechanisms may be used therapeutically to prevent rejection of transplanted organs. Particularly, current research in the Tang lab focuses on regulatory T cells, a small population of white blood cells that are essential for preventing damages caused by the over activation of the immune system. The Tang lab has shown in animal models that infusion of regulatory T cells can reverse type 1 diabetes, a disease caused by immune destruction of insulin-producing cells in the pancreatic islets. Similarly, regulatory T cell therapy in animal models can prevent rejection of transplanted organs in animal models. The research group has developed processes to isolate and grow human regulatory T cells and obtained FDA approval to evaluate regulatory T cell therapy in organ transplant recipients. The goal of this therapy is to prevent graft rejection so that patients don’t have to take costly and often toxic immunosuppressive drugs for the rest of their lives.
Immune tolerance, regulatory T cells, autoimmune diseases, organ transplantation, islet transplantation, cellular therapy.
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