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Eric Chow, PhD

TitleAssistant Professor
SchoolUCSF School of Medicine
DepartmentBiochemistry and Biophysics
Address600 16th St
San Francisco CA 94158
Phone415-418-3658
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    Eric Chow, PhD is an assistant professor in the Department of Biochemistry and Biophysics and Director of the Center for Advanced Technology (CAT) at UCSF. The CAT evaluates and brings new technologies top campus that are available to all UCSF labs and provides guidance for projects. Over the past decade, the CAT has been a hub for Next Generation Sequencing (NGS) at UCSF and beyond, supporting the development of NGS-based non-invasive pre-natal testing and pathogen diagnostics. Dr. Chow also runs a research program to devise new applications for NGS and to develop rapid pathogen detection systems in resource poor settings. He received his BA from the University of California, Berkeley, and his PhD performing genomic research in Tuberculosis at UCSF.


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    BRASL - A rapid Barcoded RNA Annealing, Selection, and Ligation assay to detect pathogens.
    NIH/NIAID R21AI120972Dec 1, 2015 - Nov 30, 2017
    Role: Principal Investigator

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    Collapse Global Health

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Doan T, Acharya NR, Pinsky BA, Sahoo MK, Chow ED, Banaei N, Budvytiene I, Cevallos V, Zhong L, Zhou Z, Lietman TM, DeRisi JL. Metagenomic DNA Sequencing for the Diagnosis of Intraocular Infections. Ophthalmology. 2017 Aug; 124(8):1247-1248. PMID: 28526549.
      View in: PubMed
    2. Doan T, Wilson MR, Crawford ED, Chow ED, Khan LM, Knopp KA, O'Donovan BD, Xia D, Hacker JK, Stewart JM, Gonzales JA, Acharya NR, DeRisi JL. Erratum to: Illuminating uveitis: metagenomic deep sequencing identifies common and rare pathogens. Genome Med. 2016 11 22; 8(1):123. PMID: 27876088.
      View in: PubMed
    3. Lim MY, LaMonte G, Lee MC, Reimer C, Tan BH, Corey V, Tjahjadi BF, Chua A, Nachon M, Wintjens R, Gedeck P, Malleret B, Renia L, Bonamy GM, Ho PC, Yeung BK, Chow ED, Lim L, Fidock DA, Diagana TT, Winzeler EA, Bifani P. UDP-galactose and acetyl-CoA transporters as Plasmodium multidrug resistance genes. Nat Microbiol. 2016 Sep 19; 16166. PMID: 27642791.
      View in: PubMed
    4. Doan T, Wilson MR, Crawford ED, Chow E, Khan LM, Knopp KA, O'Donovan BD, Xia D, Hacker JK, Stewart JM, Gonzales JA, Acharya NR, DeRisi JL. Illuminating uveitis: metagenomic deep sequencing identifies common and rare pathogens. Genome Med. 2016 08 25; 8(1):90. PMID: 27562436; PMCID: PMC4997733.
    5. Mavor D, Barlow K, Thompson S, Barad BA, Bonny AR, Cario CL, Gaskins G, Liu Z, Deming L, Axen SD, Caceres E, Chen W, Cuesta A, Gate R, Green EM, Hulce KR, Ji W, Kenner LR, Mensa B, Morinishi LS, Moss SM, Mravic M, Muir RK, Niekamp S, Nnadi CI, Palovcak E, Poss EM, Ross TD, Salcedo EC, See S, Subramaniam M, Wong AW, Li J, Thorn KS, Ó Conchúir ST, Roscoe BP, Chow E, DeRisi JL, Kortemme T, Bolon DN, Fraser JS. Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting. Elife. 2016 Apr 25; 5. PMID: 27111525; PMCID: PMC4862753.
    6. Gu W, Crawford ED, O'Donovan BD, Wilson MR, Chow ED, Retallack H, DeRisi JL. Depletion of Abundant Sequences by Hybridization (DASH): using Cas9 to remove unwanted high-abundance species in sequencing libraries and molecular counting applications. Genome Biol. 2016 Mar 04; 17:41. PMID: 26944702; PMCID: PMC4778327.
    7. Stieglitz E, Troup CB, Gelston LC, Haliburton J, Chow ED, Yu KB, Akutagawa J, Taylor-Weiner AN, Liu YL, Wang YD, Beckman K, Emanuel PD, Braun BS, Abate A, Gerbing RB, Alonzo TA, Loh ML. Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia. Blood. 2015 Jan 15; 125(3):516-24. PMID: 25395418; PMCID: PMC4296011.
    8. Ndao M, Nath-Chowdhury M, Sajid M, Marcus V, Mashiyama ST, Sakanari J, Chow E, Mackey Z, Land KM, Jacobson MP, Kalyanaraman C, McKerrow JH, Arrowood MJ, Caffrey CR. A cysteine protease inhibitor rescues mice from a lethal Cryptosporidium parvum infection. Antimicrob Agents Chemother. 2013 Dec; 57(12):6063-73. PMID: 24060869; PMCID: PMC3837922.
    9. Ouellet H, Chow ED, Guan S, Cox JS, Burlingame AL, de Montellano PR. Genetic and mass spectrometric tools for elucidating the physiological function(s) of cytochrome P450 enzymes from Mycobacterium tuberculosis. Methods Mol Biol. 2013; 987:79-94. PMID: 23475669.
      View in: PubMed
    10. Chow ED, Cox JS. TB lipidomics--the final frontier. Chem Biol. 2011 Dec 23; 18(12):1517-8. PMID: 22195552; PMCID: PMC3661412.
    11. Ouellet H, Guan S, Johnston JB, Chow ED, Kells PM, Burlingame AL, Cox JS, Podust LM, de Montellano PR. Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one. Mol Microbiol. 2010 Aug; 77(3):730-42. PMID: 20545858; PMCID: PMC2909382.
    12. Liu OW, Chun CD, Chow ED, Chen C, Madhani HD, Noble SM. Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans. Cell. 2008 Oct 03; 135(1):174-88. PMID: 18854164; PMCID: PMC2628477.
    13. Chow ED, Liu OW, O'Brien S, Madhani HD. Exploration of whole-genome responses of the human AIDS-associated yeast pathogen Cryptococcus neoformans var grubii: nitric oxide stress and body temperature. Curr Genet. 2007 Sep; 52(3-4):137-48. PMID: 17661046.
      View in: PubMed
    14. Liu OW, Kelly MJ, Chow ED, Madhani HD. Parallel beta-helix proteins required for accurate capsule polysaccharide synthesis and virulence in the yeast Cryptococcus neoformans. Eukaryot Cell. 2007 Apr; 6(4):630-40. PMID: 17337638; PMCID: PMC1865648.
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