Linda Giudice, MD, PhD

Title(s)Professor, Ob/Gyn, Reproductive Sciences
SchoolSchool of Medicine
Address513 Parnassus Ave, HSE, #1600
San Francisco CA 94143
Phone415-502-4742
ORCID ORCID Icon0000-0002-1677-0822 Additional info
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    Other Positions
    Title(s)Obstetrics, Gynecology and Reproductive Sciences


    Collapse Biography 
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    Stanford UniversityM.D.1982School of Medicine

    Collapse Overview 
    Collapse Overview
    Linda C. Giudice, MD, PhD is Distinguished Professor, Chair Emerita, and the Robert B. Jaffe MD Endowed Professor in the Reproductive Sciences in the Department of Obstetrics, Gynecology and Reproductive Sciences at the University of California, San Francisco (UCSF). She is a biochemist and reproductive endocrinologist specializing in endometriosis and infertility. Her research focuses on human endometrial function and regeneration, genetics and epigenetics of endometriosis, placental-uterine interactions relevant to pregnancy outcomes, and evaluating the evidence of environmental impacts on reproductive health and human development. She has mentored over 250 students, fellows and faculty, authored > 300 peer-reviewed publications, and is co-editor of 6 textbooks on women’s health, reproductive environmental health, endocrinology, endometrium and endometriosis. She is Past-President of the American Society for Reproductive Medicine, the Society for Gynecologic Investigation, President of the World Endometriosis Society, President-elect of the International Federation of Fertility Societies, and Chair of the FIGO (International Federation of Gynecology and Obstetrics) Reproductive and Developmental Environmental Health Working Group. Dr. Giudice is on the UCSF Steering Committee on Women’s Precision Medicine, the March of Dimes Scientific Advisory Council, and is an elected member of the U.S. National Academy of Medicine and the U.S. National Academy of Inventors.

    Collapse Research 
    Collapse Research Activities and Funding
    UCSF Stanford Endometriosis Center for Discovery, Innovation, Training and Community Engagement
    NIH P01HD106414Aug 1, 2021 - Jul 31, 2026
    Role: Principal Investigator
    Integrative Analysis of Genomic, Epigenomic and Phenotypic Data for Disease Stratification of Endometriosis
    NIH R01HD089511Sep 26, 2016 - Apr 30, 2021
    Role: Principal Investigator
    Exploring HIV-Host Interactions in the Female Reproductive Tract
    NIH P01AI083050Sep 1, 2009 - Aug 31, 2015
    Role: Co-Principal Investigator
    Origins and Biological Consequences of Human Infertility
    NIH U54HD055764May 3, 2007 - Mar 31, 2017
    Role: Principal Investigator
    Center for Research, Innovation and Training in Reproduction and Infertility
    NIH P50HD055764Apr 1, 2007 - Mar 31, 2023
    Role: Principal Investigator
    Summit on Environmental Challenges to Reproductive Health and Fertility
    NIH R13ES015427Sep 15, 2006 - Aug 31, 2007
    Role: Principal Investigator
    Mentoring &Interdisciplinary Research in Women's Health
    NIH K12HD043452Sep 27, 2002 - Dec 31, 2008
    Role: Co-Principal Investigator
    Gordon Research Conference on Reproductive Tract Biology
    NIH R13HD042663Jun 19, 2002 - May 31, 2003
    Role: Principal Investigator
    Federally Registered Human Embryonic Stem Cell Center
    NIH R24RR017498May 1, 2002 - Jul 31, 2007
    Role: Principal Investigator
    Role of IGF-II in Human Trophoblast-Decidua Interactions
    NIH U01HD042298Apr 1, 2002 - Mar 31, 2008
    Role: Principal Investigator
    HYPOXIA, IGFBP-1, AND HUMAN FETAL GROWTH
    NIH R01HD036732Mar 1, 2000 - Aug 31, 2004
    Role: Principal Investigator
    Women's Reproductive Health Research
    NIH K12HD001262Sep 30, 1998 - Jun 30, 2025
    Role: Co-Principal Investigator
    Gonadal and Endometrial Function in Human Reproduction
    NIH U54HD031398Apr 7, 1997 - Mar 31, 2008
    Role: Co-Principal Investigator
    ROLE OF IGF IN HUMAN OVARY
    NIH R01HD031579May 1, 1994 - Sep 30, 2008
    Role: Principal Investigator
    INSULIN-LIKE GROWTH FACTOR SYSTEM IN OVIDUCT
    NIH R03HD028079May 1, 1991 - Apr 30, 1993
    Role: Principal Investigator
    IGF BINDING PROTEINS AND HUMAN ENDOMETRIUM
    NIH R01HD025220Apr 1, 1990 - Jul 31, 2002
    Role: Principal Investigator
    GENE EXPRESSION IN ENDOMETRIUM
    NIH R29HD025220Apr 1, 1990 - Mar 31, 1996
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000070Dec 1, 1978 - Nov 30, 2011
    Role: Co-Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Identifying therapeutic candidates for endometriosis through a transcriptomics-based drug repositioning approach. iScience. 2024 Apr 19; 27(4):109388. Oskotsky TT, Bhoja A, Bunis D, Le BL, Tang AS, Kosti I, Li C, Houshdaran S, Sen S, Vallvé-Juanico J, Wang W, Arthurs E, Govil A, Mahoney L, Lang L, Gaudilliere B, Stevenson DK, Irwin JC, Giudice LC, McAllister SL, Sirota M. PMID: 38510116; PMCID: PMC10952035.
      View in: PubMed   Mentions:
    2. Two-year efficacy and safety of relugolix combination therapy in women with endometriosis-associated pain: SPIRIT open-label extension study. Hum Reprod. 2024 Mar 01; 39(3):526-537. Becker CM, Johnson NP, As-Sanie S, Arjona Ferreira JC, Abrao MS, Wilk K, Imm SJ, Mathur V, Perry JS, Wagman RB, Giudice LC. PMID: 38243752; PMCID: PMC10905503.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    3. Time for global health policy and research leaders to prioritize endometriosis. Nat Commun. 2023 Dec 04; 14(1):8028. Giudice LC, Horne AW, Missmer SA. PMID: 38049392; PMCID: PMC10696045.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. A Plain Language Summary to learn about relugolix combination therapy for the treatment of pain associated with endometriosis. Pain Manag. 2023 Nov; 13(11):631-640. Giudice LC, As-Sanie S, Arjona Ferreira JC, Becker CM, Abrao MS, Lessey BA, Dynowski K, Wilk K, Li Y, Mathur V, Wagman RB, Johnson NP. PMID: 37982388.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Endometriosis in the era of precision medicine and impact on sexual and reproductive health across the lifespan and in diverse populations. FASEB J. 2023 09; 37(9):e23130. Giudice LC, Oskotsky TT, Falako S, Opoku-Anane J, Sirota M. PMID: 37641572; PMCID: PMC10503213.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    6. Global endometrial DNA methylation analysis reveals insights into mQTL regulation and associated endometriosis disease risk and endometrial function. Commun Biol. 2023 08 16; 6(1):780. Mortlock S, Houshdaran S, Kosti I, Rahmioglu N, Nezhat C, Vitonis AF, Andrews SV, Grosjean P, Paranjpe M, Horne AW, Jacoby A, Lager J, Opoku-Anane J, Vo KC, Manvelyan E, Sen S, Ghukasyan Z, Collins F, Santamaria X, Saunders P, Kober K, McRae AF, Terry KL, Vallvé-Juanico J, Becker C, Rogers PAW, Irwin JC, Zondervan K, Montgomery GW, Missmer S, Sirota M, Giudice L. PMID: 37587191; PMCID: PMC10432557.
      View in: PubMed   Mentions: 2  Translation:HumansCells
    7. B-cell lymphoma 6 expression significantly differs by the uterine preparation method used for frozen embryo transfer. Fertil Steril. 2023 08; 120(2):305-311. Huang D, Chan M, Solomon M, Cedars MI, Giudice LC, Cakmak H. PMID: 37085097.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Leveraging electronic health records to identify risk factors for recurrent pregnancy loss across two medical centers: a case-control study. Res Sq. 2023 Mar 31. Roger J, Xie F, Costello J, Tang A, Liu J, Oskotsky T, Woldemariam S, Kosti I, Le B, Snyder MP, Giudice LC, Torgerson D, Shaw GM, Stevenson DK, Rajkovic A, Glymour MM, Aghaeepour N, Cakmak H, Lathi RB, Sirota M. PMID: 36993325; PMCID: PMC10055527.
      View in: PubMed   Mentions:
    9. The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nat Genet. 2023 03; 55(3):423-436. Rahmioglu N, Mortlock S, Ghiasi M, Møller PL, Stefansdottir L, Galarneau G, Turman C, Danning R, Law MH, Sapkota Y, Christofidou P, Skarp S, Giri A, Banasik K, Krassowski M, Lepamets M, Marciniak B, Nõukas M, Perro D, Sliz E, Sobalska-Kwapis M, Thorleifsson G, Topbas-Selcuki NF, Vitonis A, Westergaard D, Arnadottir R, Burgdorf KS, Campbell A, Cheuk CSK, Clementi C, Cook J, De Vivo I, DiVasta A, Dorien O, Donoghue JF, Edwards T, Fontanillas P, Fung JN, Geirsson RT, Girling JE, Harkki P, Harris HR, Healey M, Heikinheimo O, Holdsworth-Carson S, Hostettler IC, Houlden H, Houshdaran S, Irwin JC, Jarvelin MR, Kamatani Y, Kennedy SH, Kepka E, Kettunen J, Kubo M, Kulig B, Kurra V, Laivuori H, Laufer MR, Lindgren CM, MacGregor S, Mangino M, Martin NG, Matalliotaki C, Matalliotakis M, Murray AD, Ndungu A, Nezhat C, Olsen CM, Opoku-Anane J, Padmanabhan S, Paranjpe M, Peters M, Polak G, Porteous DJ, Rabban J, Rexrode KM, Romanowicz H, Saare M, Saavalainen L, Schork AJ, Sen S, Shafrir AL, Siewierska-Górska A, Slomka M, Smith BH, Smolarz B, Szaflik T, Szyllo K, Takahashi A, Terry KL, Tomassetti C, Treloar SA, Vanhie A, Vincent K, Vo KC, Werring DJ, Zeggini E, Zervou MI, DBDS Genomic Consortium, FinnGen Study, FinnGen Endometriosis Taskforce, Celmatix Research Team, 23andMe Research Team, Adachi S, Buring JE, Ridker PM, D'Hooghe T, Goulielmos GN, Hapangama DK, Hayward C, Horne AW, Low SK, Martikainen H, Chasman DI, Rogers PAW, Saunders PT, Sirota M, Spector T, Strapagiel D, Tung JY, Whiteman DC, Giudice LC, Velez-Edwards DR, Uimari O, Kraft P, Salumets A, Nyholt DR, Mägi R, Stefansson K, Becker CM, Yurttas-Beim P, Steinthorsdottir V, Nyegaard M, Missmer SA, Montgomery GW, Morris AP, Zondervan KT. PMID: 36914876; PMCID: PMC10042257.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    10. Systematic review of climate change effects on reproductive health. Fertil Steril. 2022 Aug; 118(2):215-223. Segal TR, Giudice LC. PMID: 35878942.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    11. Once daily oral relugolix combination therapy versus placebo in patients with endometriosis-associated pain: two replicate phase 3, randomised, double-blind, studies (SPIRIT 1 and 2). Lancet. 2022 06 18; 399(10343):2267-2279. Giudice LC, As-Sanie S, Arjona Ferreira JC, Becker CM, Abrao MS, Lessey BA, Brown E, Dynowski K, Wilk K, Li Y, Mathur V, Warsi QA, Wagman RB, Johnson NP. PMID: 35717987.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    12. Response to Boulicault et al. (2022) from women in the field. Hum Fertil (Camb). 2022 12; 25(5):1003-1004. Gore AC, Giudice LC, Flaws JA, Hunt PA. PMID: 35686468.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Commentary on the climate crisis and Women's health: Time for action. Int J Gynaecol Obstet. 2023 02; 160(2):455-456. Giudice LC. PMID: 35608325.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Transcriptomic analysis supports collective endometrial cell migration in the pathogenesis of adenomyosis. Reprod Biomed Online. 2022 09; 45(3):519-530. Zhai J, Li S, Sen S, Vallvé-Juanico J, Irwin JC, Vo KC, Wan J, Du Y, Chen ZJ, Giudice LC. PMID: 35773139; PMCID: PMC9976941.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    15. The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans. Science. 2022 05 13; 376(6594):eabl4896. Tabula Sapiens Consortium*, Jones RC, Karkanias J, Krasnow MA, Pisco AO, Quake SR, Salzman J, Yosef N, Bulthaup B, Brown P, Harper W, Hemenez M, Ponnusamy R, Salehi A, Sanagavarapu BA, Spallino E, Aaron KA, Concepcion W, Gardner JM, Kelly B, Neidlinger N, Wang Z, Crasta S, Kolluru S, Morri M, Tan SY, Travaglini KJ, Xu C, Alcántara-Hernández M, Almanzar N, Antony J, Beyersdorf B, Burhan D, Calcuttawala K, Carter MM, Chan CKF, Chang CA, Chang S, Colville A, Culver RN, Cvijovic I, D'Amato G, Ezran C, Galdos FX, Gillich A, Goodyer WR, Hang Y, Hayashi A, Houshdaran S, Huang X, Irwin JC, Jang S, Juanico JV, Kershner AM, Kim S, Kiss B, Kong W, Kumar ME, Kuo AH, Li B, Loeb GB, Lu WJ, Mantri S, Markovic M, McAlpine PL, de Morree A, Mrouj K, Mukherjee S, Muser T, Neuhöfer P, Nguyen TD, Perez K, Puluca N, Qi Z, Rao P, Raquer-McKay H, Schaum N, Scott B, Seddighzadeh B, Segal J, Sen S, Sikandar S, Spencer SP, Steffes LC, Subramaniam VR, Swarup A, Swift M, Van Treuren W, Trimm E, Veizades S, Vijayakumar S, Vo KC, Vorperian SK, Wang W, Weinstein HNW, Winkler J, Wu TTH, Xie J, Yung AR, Zhang Y, Detweiler AM, Mekonen H, Neff NF, Sit RV, Tan M, Yan J, Bean GR, Charu V, Forgó E, Martin BA, Ozawa MG, Silva O, Toland A, Vemuri VNP, Afik S, Awayan K, Botvinnik OB, Byrne A, Chen M, Dehghannasiri R, Gayoso A, Granados AA, Li Q, Mahmoudabadi G, McGeever A, Olivieri JE, Park M, Ravikumar N, Stanley G, Tan W, Tarashansky AJ, Vanheusden R, Wang P, Wang S, Xing G, Dethlefsen L, Ezran C, Gillich A, Hang Y, Ho PY, Irwin JC, Jang S, Leylek R, Liu S, Maltzman JS, Metzger RJ, Phansalkar R, Sasagawa K, Sinha R, Song H, Swarup A, Trimm E, Veizades S, Wang B, Beachy PA, Clarke MF, Giudice LC, Huang FW, Huang KC, Idoyaga J, Kim SK, Kuo CS, Nguyen P, Rando TA, Red-Horse K, Reiter J, Relman DA, Sonnenburg JL, Wu A, Wu SM, Wyss-Coray T. PMID: 35549404; PMCID: PMC9812260.
      View in: PubMed   Mentions: 185     Fields:    Translation:HumansCells
    16. Deep immunophenotyping reveals endometriosis is marked by dysregulation of the mononuclear phagocytic system in endometrium and peripheral blood. BMC Med. 2022 04 15; 20(1):158. Vallvé-Juanico J, George AF, Sen S, Thomas R, Shin MG, Kushnoor D, Vásquez JJ, Vo KC, Irwin JC, Roan NR, Combes AJ, Giudice LC. PMID: 35421980; PMCID: PMC9011995.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    17. Nutritional interventions to ameliorate the effect of endocrine disruptors on human reproductive health: A semi-structured review from FIGO. Int J Gynaecol Obstet. 2022 Jun; 157(3):489-501. Corbett GA, Lee S, Woodruff TJ, Hanson M, Hod M, Charlesworth AM, Giudice L, Conry J, McAuliffe FM, International Federation of Gynecology and Obstetrics (FIGO) Committee on Impact of Pregnancy on Lon. PMID: 35122246; PMCID: PMC9305939.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    18. Whole-Tissue Deconvolution and scRNAseq Analysis Identify Altered Endometrial Cellular Compositions and Functionality Associated With Endometriosis. Front Immunol. 2021; 12:788315. Bunis DG, Wang W, Vallvé-Juanico J, Houshdaran S, Sen S, Ben Soltane I, Kosti I, Vo KC, Irwin JC, Giudice LC, Sirota M. PMID: 35069565; PMCID: PMC8766492.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    19. Climate change, women's health, and the role of obstetricians and gynecologists in leadership. Int J Gynaecol Obstet. 2021 Dec; 155(3):345-356. Giudice LC, Llamas-Clark EF, DeNicola N, Pandipati S, Zlatnik MG, Decena DCD, Woodruff TJ, Conry JA, FIGO Committee on Climate Change and Toxic Environmental Exposures. PMID: 34694628; PMCID: PMC9298078.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsPHPublic Health
    20. Environmental impact on reproductive health and risk mitigating strategies. Curr Opin Obstet Gynecol. 2021 08 01; 33(4):343-349. Giudice LC. PMID: 34039883.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    21. Elevated levels of perfluoroalkyl substances in breast cancer patients within the Greater Manila Area. Chemosphere. 2022 Jan; 286(Pt 1):131545. Velarde MC, Chan AFO, Sajo MEJV, Zakharevich I, Melamed J, Uy GLB, Teves JMY, Corachea AJM, Valparaiso AP, Macalindong SS, Cabaluna ND, Dofitas RB, Giudice LC, Gerona RR. PMID: 34293563.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    22. In Silico, In Vitro, and In Vivo Analysis Identifies Endometrial Circadian Clock Genes in Recurrent Implantation Failure. J Clin Endocrinol Metab. 2021 06 16; 106(7):2077-2091. Zhai J, Li S, Hu J, Gao M, Sun Y, Chen ZJ, Giudice LC, Du Y. PMID: 33619544; PMCID: PMC8502449.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Endometrial function in women with polycystic ovary syndrome: a comprehensive review. Hum Reprod Update. 2021 04 21; 27(3):584-618. Palomba S, Piltonen TT, Giudice LC. PMID: 33302299.
      View in: PubMed   Mentions: 73     Fields:    Translation:Humans
    24. Randomized Trial of a Vaccine Regimen to Prevent Chronic HCV Infection. N Engl J Med. 2021 02 11; 384(6):541-549. Page K, Melia MT, Veenhuis RT, Winter M, Rousseau KE, Massaccesi G, Osburn WO, Forman M, Thomas E, Thornton K, Wagner K, Vassilev V, Lin L, Lum PJ, Giudice LC, Stein E, Asher A, Chang S, Gorman R, Ghany MG, Liang TJ, Wierzbicki MR, Scarselli E, Nicosia A, Folgori A, Capone S, Cox AL. PMID: 33567193; PMCID: PMC8367093.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    25. Could children born to mothers with COVID-19 be more prone to non-communicable diseases? Acta Paediatr. 2021 Apr; 110(4):1367-1368. Malamitsi-Puchner A, Briana DD, Giudice L, Di Renzo GC. PMID: 33438264; PMCID: PMC8013839.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    26. Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium. Mol Hum Reprod. 2021 01 22; 27(1). Marla S, Mortlock S, Houshdaran S, Fung J, McKinnon B, Holdsworth-Carson SJ, Girling JE, Rogers PAW, Giudice LC, Montgomery GW. PMID: 33394050; PMCID: PMC8453628.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    27. Patterns of sex hormone receptor expression in stimulated endometrium from oocyte donors. Hum Fertil (Camb). 2022 Oct; 25(4):662-669. Manvelyan E, Houshdaran S, Irwin JC, Giudice LC, Aghajanova L. PMID: 33464141.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    28. Eye to the Future in Adenomyosis Research. Semin Reprod Med. 2020 May; 38(2-03):197-200. Halvorson LM, Giudice LC, Stewart EA. PMID: 33307559.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    29. Standardizing definitions and reporting guidelines for the infertility core outcome set: an international consensus development study†  ‡. Hum Reprod. 2020 12 01; 35(12):2735-2745. Duffy JMN, Bhattacharya S, Bhattacharya S, Bofill M, Collura B, Curtis C, Evers JLH, Giudice LC, Farquharson RG, Franik S, Hickey M, Hull ML, Jordan V, Khalaf Y, Legro RS, Lensen S, Mavrelos D, Mol BW, Niederberger C, Ng EHY, Puscasiu L, Repping S, Sarris I, Showell M, Strandell A, Vail A, van Wely M, Vercoe M, Vuong NL, Wang AY, Wang R, Wilkinson J, Youssef MA, Farquhar CM, Core Outcome Measure for Infertility Trials (COMMIT) initiative, Abou-Setta AM, Aguilera JJ, AlAhwany H, Atanda OOA, Balkenende EME, Barnhart KT, Beebeejaun Y, Chambers GM, Chughtai AA, Cuevas-Sáiz I, Curtis C, D'Angelo A, Dubois DD, Duckitt K, Encinas C, Gerval MO, Giang NH, Gibreel A, Gingel LJ, Glanville EJ, Glujovsky D, Granne I, Griesinger G, Repromed DG, Hamzehgardeshi Z, Hirsch M, Horton M, Jain S, Perez MJ, Jones CA, Kamath MS, Knijnenburg J, Kostova E, La Marca A, Khac Le T, Leader A, Leeviers B, Chinese JL, Loto OM, Marks KL, Martinez-Vazquez RM, McTavish AR, Mills DJ, Nair RR, Nguyen DTP, Otter AS, Pacey AA, Rautakallio-Hokkanen S, Sadler LC, Sagle P, Schwarze JE, Shapiro HM, Simpson JL, Siristatidis CS, Sood A, Strawbridge C, Torrance HL, Tran CT, Votteler EL, Wang CC, Watson A, Yossry M. PMID: 33252643; PMCID: PMC7744157.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    30. Top 10 priorities for future infertility research: an international consensus development study†  ‡. Hum Reprod. 2020 12 01; 35(12):2715-2724. Duffy JMN, Adamson GD, Benson E, Bhattacharya S, Bhattacharya S, Bofill M, Brian K, Collura B, Curtis C, Evers JLH, Farquharson RG, Fincham A, Franik S, Giudice LC, Glanville E, Hickey M, Horne AW, Hull ML, Johnson NP, Jordan V, Khalaf Y, Knijnenburg JML, Legro RS, Lensen S, MacKenzie J, Mavrelos D, Mol BW, Morbeck DE, Nagels H, Ng EHY, Niederberger C, Otter AS, Puscasiu L, Rautakallio-Hokkanen S, Sadler L, Sarris I, Showell M, Stewart J, Strandell A, Strawbridge C, Vail A, van Wely M, Vercoe M, Vuong NL, Wang AY, Wang R, Wilkinson J, Wong K, Wong TY, Farquhar CM, Priority Setting Partnership for Infertility, AlAhwany H, Balaban O, Barton F, Beebeejaun Y, Boivin J, Bosteels JJA, Calhaz-Jorge C, D’Angelo A, F. Dann L, J. De Jonge C, du Mez E, A. Ferriani R, Gerval MO, J. Gingel L, Greenblatt EM, Hartshorne G, Helliwell C, Hughes LJ, Jo J, Jovanovic J, Kiesel L, Kietpeerakool C, Kostova E, Kucuk T, Kumar R, Lawrence RL, Lee N, Lindemann KE, Loto OM, Lutjen PJ, MacKinven M, Mascarenhas M, McLaughlin H, Mourad SM, Nguyen LK, Norman RJ, Olic M, Overfield KL, Parker-Harris M, Repping S, Rizzo R, Salacone P, Saunders CH, Sengupta R, Sfontouris IA, Silverman NR, Torrance HL, Uphoff EP, Wakeman SA, Wischmann T, Woodward BJ, Youssef MA. PMID: 33252677; PMCID: PMC7744161.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    31. Developing a core outcome set for future infertility research: an international consensus development study†  ‡. Hum Reprod. 2020 12 01; 35(12):2725-2734. Duffy JMN, AlAhwany H, Bhattacharya S, Collura B, Curtis C, Evers JLH, Farquharson RG, Franik S, Giudice LC, Khalaf Y, Knijnenburg JML, Leeners B, Legro RS, Lensen S, Vazquez-Niebla JC, Mavrelos D, Mol BWJ, Niederberger C, Ng EHY, Otter AS, Puscasiu L, Rautakallio-Hokkanen S, Repping S, Sarris I, Simpson JL, Strandell A, Strawbridge C, Torrance HL, Vail A, van Wely M, Vercoe MA, Vuong NL, Wang AY, Wang R, Wilkinson J, Youssef MA, Farquhar CM, Core Outcome Measure for Infertility Trials (COMMIT) initiative. PMID: 33252685; PMCID: PMC7744160.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    32. Top 10 priorities for future infertility research: an international consensus development study. Fertil Steril. 2021 01; 115(1):180-190. Duffy JMN, Adamson GD, Benson E, Bhattacharya S, Bhattacharya S, Bofill M, Brian K, Collura B, Curtis C, Evers JLH, Farquharson RG, Fincham A, Franik S, Giudice LC, Glanville E, Hickey M, Horne AW, Hull ML, Johnson NP, Jordan V, Khalaf Y, Knijnenburg JML, Legro RS, Lensen S, MacKenzie J, Mavrelos D, Mol BW, Morbeck DE, Nagels H, Ng EHY, Niederberger C, Otter AS, Puscasiu L, Rautakallio-Hokkanen S, Sadler L, Sarris I, Showell M, Stewart J, Strandell A, Strawbridge C, Vail A, van Wely M, Vercoe M, Vuong NL, Wang AY, Wang R, Wilkinson J, Wong K, Wong TY, Farquhar CM, Priority Setting Partnership for Infertility. PMID: 33272617.
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    33. Developing a core outcome set for future infertility research: an international consensus development study. Fertil Steril. 2021 01; 115(1):191-200. Duffy JMN, AlAhwany H, Bhattacharya S, Collura B, Curtis C, Evers JLH, Farquharson RG, Franik S, Giudice LC, Khalaf Y, Knijnenburg JML, Leeners B, Legro RS, Lensen S, Vazquez-Niebla JC, Mavrelos D, Mol BWJ, Niederberger C, Ng EHY, Otter AS, Puscasiu L, Rautakallio-Hokkanen S, Repping S, Sarris I, Simpson JL, Strandell A, Strawbridge C, Torrance HL, Vail A, van Wely M, Vercoe MA, Vuong NL, Wang AY, Wang R, Wilkinson J, Youssef MA, Farquhar CM, Core Outcome Measure for Infertility Trials (COMMIT) initiative. PMID: 33272618.
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    34. Standardizing definitions and reporting guidelines for the infertility core outcome set: an international consensus development study. Fertil Steril. 2021 01; 115(1):201-212. Duffy JMN, Bhattacharya S, Bhattacharya S, Bofill M, Collura B, Curtis C, Evers JLH, Giudice LC, Farquharson RG, Franik S, Hickey M, Hull ML, Jordan V, Khalaf Y, Legro RS, Lensen S, Mavrelos D, Mol BW, Niederberger C, Ng EHY, Puscasiu L, Repping S, Sarris I, Showell M, Strandell A, Vail A, van Wely M, Vercoe M, Vuong NL, Wang AY, Wang R, Wilkinson J, Youssef MA, Farquhar CM, Core Outcome Measure for Infertility Trials (COMMIT) initiative. PMID: 33272619.
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    35. Cellular Origins of Endometriosis: Towards Novel Diagnostics and Therapeutics. Semin Reprod Med. 2020 05; 38(2-03):201-215. Filby CE, Rombauts L, Montgomery GW, Giudice LC, Gargett CE. PMID: 33176364.
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    36. Adenomyosis: Mechanisms and Pathogenesis. Semin Reprod Med. 2020 May; 38(2-03):129-143. Zhai J, Vannuccini S, Petraglia F, Giudice LC. PMID: 33032339; PMCID: PMC7932680.
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    37. Multidimensional transcriptomic mapping of human endometrium at single-cell resolution. Nat Med. 2020 10; 26(10):1513-1514. Giudice LC. PMID: 32929267.
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    38. Cytotrophoblast extracellular vesicles enhance decidual cell secretion of immune modulators via TNFα. Development. 2020 09 08; 147(17). Taylor SK, Houshdaran S, Robinson JF, Gormley MJ, Kwan EY, Kapidzic M, Schilling B, Giudice LC, Fisher SJ. PMID: 32747437; PMCID: PMC7502596.
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    39. The global impact of COVID-19 on infertility services. Glob Reprod Health. 2020 Aug 13; 5. Ory SJ, Miller KA, Horton M, Giudice L. PMID: 34192216; PMCID: PMC7434007.
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    40. m6A RNA Methylation Regulators Contribute to Eutopic Endometrium and Myometrium Dysfunction in Adenomyosis. Front Genet. 2020; 11:716. Zhai J, Li S, Sen S, Opoku-Anane J, Du Y, Chen ZJ, Giudice LC. PMID: 32719721; PMCID: PMC7350935.
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    41. Steroid hormones regulate genome-wide epigenetic programming and gene transcription in human endometrial cells with marked aberrancies in endometriosis. PLoS Genet. 2020 06; 16(6):e1008601. Houshdaran S, Oke AB, Fung JC, Vo KC, Nezhat C, Giudice LC. PMID: 32555663; PMCID: PMC7299312.
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    42. A Clarion Warning About Pregnancy Outcomes and the Climate Crisis. JAMA Netw Open. 2020 06 01; 3(6):e208811. Giudice LC. PMID: 32556255.
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    43. HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread. Elife. 2020 05 26; 9. Ma T, Luo X, George AF, Mukherjee G, Sen N, Spitzer TL, Giudice LC, Greene WC, Roan NR. PMID: 32452381; PMCID: PMC7250576.
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    44. Parallel studies of mucosal immunity in the reproductive and gastrointestinal mucosa of HIV-infected women. Am J Reprod Immunol. 2020 07; 84(1):e13246. Shanmugasundaram U, Critchfield JW, Giudice LC, Smith-McCune K, Greenblatt RM, Shacklett BL. PMID: 32301548; PMCID: PMC7302888.
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    45. Authors' Reply. J Minim Invasive Gynecol. 2020 Sep - Oct; 27(6):1427. Montgomery GW, Mortlock S, Giudice LC. PMID: 32339756.
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    46. Differential Effects of the Hormonal and Copper Intrauterine Device on the Endometrial Transcriptome. Sci Rep. 2020 04 23; 10(1):6888. Smith-McCune K, Thomas R, Averbach S, Seidman D, Takeda M, Houshdaran S, Giudice LC. PMID: 32327684; PMCID: PMC7181869.
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    47. Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. Int J Mol Sci. 2020 Apr 09; 21(7). Houshdaran S, Chen JC, Vallvé-Juanico J, Balayan S, Vo KC, Smith-McCune K, Greenblatt RM, Irwin JC, Giudice LC. PMID: 32283828; PMCID: PMC7177488.
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    48. Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling. Hum Reprod. 2020 03 27; 35(3):617-640. George AF, Jang KS, Nyegaard M, Neidleman J, Spitzer TL, Xie G, Chen JC, Herzig E, Laustsen A, Marques de Menezes EG, Houshdaran S, Pilcher CD, Norris PJ, Jakobsen MR, Greene WC, Giudice LC, Roan NR. PMID: 32219408; PMCID: PMC7105328.
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    49. A Pilot Cancer-Phenome Biobanking System in a Low-Resource Southeast Asian Setting: The Philippine General Hospital Biobank Experience. Biopreserv Biobank. 2020 Jun; 18(3):180-188. Sajo MEJV, Teves JMY, Corachea AJM, Diaz LA, Chan AFO, Valparaiso AP, Dy Echo AVV, Macalindong SS, Uy GLB, Dofitas RB, Habana MAE, Gerona RR, Irwin JC, Giudice LC, Velarde MC. PMID: 32202927.
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    50. Macrophages display proinflammatory phenotypes in the eutopic endometrium of women with endometriosis with relevance to an infectious etiology of the disease. Fertil Steril. 2019 12; 112(6):1118-1128. Vallvé-Juanico J, Santamaria X, Vo KC, Houshdaran S, Giudice LC. PMID: 31843088; PMCID: PMC6944306.
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    51. Should Genetics Now Be Considered the Pre-eminent Etiologic Factor in Endometriosis? J Minim Invasive Gynecol. 2020 02; 27(2):280-286. Montgomery GW, Mortlock S, Giudice LC. PMID: 31683028; PMCID: PMC7863762.
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    52. Before the beginning: environmental exposures and reproductive and obstetrical outcomes. Fertil Steril. 2019 10; 112(4):613-621. Segal TR, Giudice LC. PMID: 31561863.
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    53. Reprint of: Pathogenesis and pathophysiology of endometriosis. Fertil Steril. 2019 10; 112(4 Suppl1):e153-e161. Burney RO, Giudice LC. PMID: 31623726.
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    54. 25 historic papers: an ASRM 75th birthday gift from Fertility and Sterility. Fertil Steril. 2019 10; 112(4 Suppl1):e2-e27. Niederberger C, Pellicer A, Simon C, Kathrins M, Goldstein M, Sigman M, Schlegel PN, Munné S, Gardner DK, Cobo A, Coutifaris C, Donnez J, Taylor HS, Giudice LC, Fauser BCJM, Lindheim SR, Rosenwaks Z, Casper RF, de Ziegler D, Gibbons WE, Paulson RJ, Laufer N, Klock SC, Mendola P, Sauer MV. PMID: 31623734.
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    55. The endometrial immune environment of women with endometriosis. Hum Reprod Update. 2019 09 11; 25(5):564-591. Vallvé-Juanico J, Houshdaran S, Giudice LC. PMID: 31424502; PMCID: PMC6737540.
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    56. Assessing research gaps and unmet needs in endometriosis. Am J Obstet Gynecol. 2019 08; 221(2):86-94. As-Sanie S, Black R, Giudice LC, Gray Valbrun T, Gupta J, Jones B, Laufer MR, Milspaw AT, Missmer SA, Norman A, Taylor RN, Wallace K, Williams Z, Yong PJ, Nebel RA. PMID: 30790565.
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    57. Clinical diagnosis of endometriosis: a call to action. Am J Obstet Gynecol. 2019 04; 220(4):354.e1-354.e12. Agarwal SK, Chapron C, Giudice LC, Laufer MR, Leyland N, Missmer SA, Singh SS, Taylor HS. PMID: 30625295.
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    58. Establishing the global working group on Reproductive and Developmental Environmental Health (RDEH): practicum of a global resource. Glob Reprod Health. 2018 Sep; 3(3). Power AM, Woodruff TJ, Conry JA, Giudice LC. PMID: 31245658; PMCID: PMC6594703.
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    59. Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma. Biol Reprod. 2018 08 01; 99(2):336-348. Martin JW, Chen JC, Neidleman J, Tatsumi K, Hu J, Giudice LC, Greene WC, Roan NR. PMID: 29518187; PMCID: PMC6084595.
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    60. Forty years of IVF. Fertil Steril. 2018 07 15; 110(2):185-324.e5. Niederberger C, Pellicer A, Cohen J, Gardner DK, Palermo GD, O'Neill CL, Chow S, Rosenwaks Z, Cobo A, Swain JE, Schoolcraft WB, Frydman R, Bishop LA, Aharon D, Gordon C, New E, Decherney A, Tan SL, Paulson RJ, Goldfarb JM, Brännström M, Donnez J, Silber S, Dolmans MM, Simpson JL, Handyside AH, Munné S, Eguizabal C, Montserrat N, Izpisua Belmonte JC, Trounson A, Simon C, Tulandi T, Giudice LC, Norman RJ, Hsueh AJ, Sun Y, Laufer N, Kochman R, Eldar-Geva T, Lunenfeld B, Ezcurra D, D'Hooghe T, Fauser BCJM, Tarlatzis BC, Meldrum DR, Casper RF, Fatemi HM, Devroey P, Galliano D, Wikland M, Sigman M, Schoor RA, Goldstein M, Lipshultz LI, Schlegel PN, Hussein A, Oates RD, Brannigan RE, Ross HE, Pennings G, Klock SC, Brown S, Van Steirteghem A, Rebar RW, LaBarbera AR. PMID: 30053940.
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    61. Long-Term Outcomes of Elagolix in Women With Endometriosis: Results From Two Extension Studies. Obstet Gynecol. 2018 07; 132(1):147-160. Surrey E, Taylor HS, Giudice L, Lessey BA, Abrao MS, Archer DF, Diamond MP, Johnson NP, Watts NB, Gallagher JC, Simon JA, Carr BR, Dmowski WP, Leyland N, Singh SS, Rechberger T, Agarwal SK, Duan WR, Schwefel B, Thomas JW, Peloso PM, Ng J, Soliman AM, Chwalisz K. PMID: 29889764.
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    62. Evaluation, validation and refinement of noninvasive diagnostic biomarkers for endometriosis (ENDOmarker): A protocol to phenotype bio-specimens for discovery and validation. Contemp Clin Trials. 2018 05; 68:1-6. Barnhart K, Giudice L, Young S, Thomas T, Diamond MP, Segars J, Youssef WA, Krawetz S, Santoro N, Eisenberg E, Zhang H, NICHD Cooperative Reproductive Medicine Network. PMID: 29524590; PMCID: PMC5899676.
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    63. In vitro evidence that platelet-rich plasma stimulates cellular processes involved in endometrial regeneration. J Assist Reprod Genet. 2018 May; 35(5):757-770. Aghajanova L, Houshdaran S, Balayan S, Manvelyan E, Irwin JC, Huddleston HG, Giudice LC. PMID: 29404863; PMCID: PMC5984879.
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    64. Effects of noncavity-distorting fibroids on endometrial gene expression and function. Biol Reprod. 2017 Oct 01; 97(4):564-576. Aghajanova L, Houshdaran S, Irwin JC, Giudice LC. PMID: 29025102; PMCID: PMC6279121.
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    65. Stromal fibroblasts from perimenopausal endometrium exhibit a different transcriptome than those from the premenopausal endometrium. Biol Reprod. 2017 Sep 01; 97(3):387-399. Erikson DW, Barragan F, Piltonen TT, Chen JC, Balayan S, Irwin JC, Giudice LC. PMID: 29024986; PMCID: PMC5803759.
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    66. Meta-signature of human endometrial receptivity: a meta-analysis and validation study of transcriptomic biomarkers. Sci Rep. 2017 08 30; 7(1):10077. Altmäe S, Koel M, Võsa U, Adler P, Suhorutšenko M, Laisk-Podar T, Kukushkina V, Saare M, Velthut-Meikas A, Krjutškov K, Aghajanova L, Lalitkumar PG, Gemzell-Danielsson K, Giudice L, Simón C, Salumets A. PMID: 28855728; PMCID: PMC5577343.
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    67. Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist. N Engl J Med. 2017 07 06; 377(1):28-40. Taylor HS, Giudice LC, Lessey BA, Abrao MS, Kotarski J, Archer DF, Diamond MP, Surrey E, Johnson NP, Watts NB, Gallagher JC, Simon JA, Carr BR, Dmowski WP, Leyland N, Rowan JP, Duan WR, Ng J, Schwefel B, Thomas JW, Jain RI, Chwalisz K. PMID: 28525302.
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    68. New Lessons about Endometriosis - Somatic Mutations and Disease Heterogeneity. N Engl J Med. 2017 05 11; 376(19):1881-1882. Montgomery GW, Giudice LC. PMID: 28489997.
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    69. Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells. PLoS Pathog. 2017 02; 13(2):e1006163. Neidleman JA, Chen JC, Kohgadai N, Müller JA, Laustsen A, Thavachelvam K, Jang KS, Stürzel CM, Jones JJ, Ochsenbauer C, Chitre A, Somsouk M, Garcia MM, Smith JF, Greenblatt RM, Münch J, Jakobsen MR, Giudice LC, Greene WC, Roan NR. PMID: 28207890; PMCID: PMC5312882.
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    70. Effects of depot-medroxyprogesterone acetate on the immune microenvironment of the human cervix and endometrium: implications for HIV susceptibility. Mucosal Immunol. 2017 09; 10(5):1270-1278. Smith-McCune KK, Hilton JF, Shanmugasundaram U, Critchfield JW, Greenblatt RM, Seidman D, Averbach S, Giudice LC, Shacklett BL. PMID: 28051087; PMCID: PMC5496803.
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    71. World Endometriosis Society consensus on the classification of endometriosis. Hum Reprod. 2017 02; 32(2):315-324. Johnson NP, Hummelshoj L, Adamson GD, Keckstein J, Taylor HS, Abrao MS, Bush D, Kiesel L, Tamimi R, Sharpe-Timms KL, Rombauts L, Giudice LC, World Endometriosis Society Sao Paulo Consortium . PMID: 27920089.
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    72. Insights from imaging the implanting embryo and the uterine environment in three dimensions. Development. 2016 12 15; 143(24):4749-4754. Arora R, Fries A, Oelerich K, Marchuk K, Sabeur K, Giudice LC, Laird DJ. PMID: 27836961; PMCID: PMC5201036.
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    73. Challenging dogma: the endometrium has a microbiome with functional consequences! Am J Obstet Gynecol. 2016 12; 215(6):682-683. Giudice LC. PMID: 27725136.
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    74. Research Priorities for Endometriosis. Reprod Sci. 2017 02; 24(2):202-226. Rogers PA, Adamson GD, Al-Jefout M, Becker CM, D'Hooghe TM, Dunselman GA, Fazleabas A, Giudice LC, Horne AW, Hull ML, Hummelshoj L, Missmer SA, Montgomery GW, Stratton P, Taylor RN, Rombauts L, Saunders PT, Vincent K, Zondervan KT, WES/WERF Consortium for Research Priorities in Endometriosis. PMID: 27368878; PMCID: PMC5933154.
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    75. Environmental toxicants: hidden players on the reproductive stage. Fertil Steril. 2016 Sep 15; 106(4):791-4. Giudice LC. PMID: 27545021.
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    76. Aberrant Endometrial DNA Methylome and Associated Gene Expression in Women with Endometriosis. Biol Reprod. 2016 11; 95(5):93. Houshdaran S, Nezhat CR, Vo KC, Zelenko Z, Irwin JC, Giudice LC. PMID: 27535958; PMCID: PMC5178151.
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    77. Effects of the levonorgestrel-releasing intrauterine device on the immune microenvironment of the human cervix and endometrium. Am J Reprod Immunol. 2016 08; 76(2):137-48. Shanmugasundaram U, Hilton JF, Critchfield JW, Greenblatt RM, Giudice LC, Averbach S, Seidman D, Shacklett BL, Smith-McCune K. PMID: 27401588; PMCID: PMC5316474.
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    78. Stanniocalcin-1 expression in normal human endometrium and dysregulation in endometriosis. Fertil Steril. 2016 Sep 01; 106(3):681-691.e1. Aghajanova L, Altmäe S, Kasvandik S, Salumets A, Stavreus-Evers A, Giudice LC. PMID: 27322879; PMCID: PMC5010972.
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    79. Global Transcriptome Abnormalities of the Eutopic Endometrium From Women With Adenomyosis. Reprod Sci. 2016 10; 23(10):1289-303. Herndon CN, Aghajanova L, Balayan S, Erikson D, Barragan F, Goldfien G, Vo KC, Hawkins S, Giudice LC. PMID: 27233751; PMCID: PMC6344825.
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    80. Moving from awareness to action on preventing patient exposure to toxic environmental chemicals. Am J Obstet Gynecol. 2016 05; 214(5):555-8. Sutton PM, Giudice LC, Woodruff TJ. PMID: 27126615; PMCID: PMC6628905.
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    81. Human Endometrial Fibroblasts Derived from Mesenchymal Progenitors Inherit Progesterone Resistance and Acquire an Inflammatory Phenotype in the Endometrial Niche in Endometriosis. Biol Reprod. 2016 05; 94(5):118. Barragan F, Irwin JC, Balayan S, Erikson DW, Chen JC, Houshdaran S, Piltonen TT, Spitzer TL, George A, Rabban JT, Nezhat C, Giudice LC. PMID: 27075616; PMCID: PMC4939744.
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    82. Cryopreservation and recovery of human endometrial epithelial cells with high viability, purity, and functional fidelity. Fertil Steril. 2016 Feb; 105(2):501-10.e1. Chen JC, Hoffman JR, Arora R, Perrone LA, Gonzalez-Gomez CJ, Vo KC, Laird DJ, Irwin JC, Giudice LC. PMID: 26515378; PMCID: PMC4744114.
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    83. International Federation of Gynecology and Obstetrics opinion on reproductive health impacts of exposure to toxic environmental chemicals. Int J Gynaecol Obstet. 2015 Dec; 131(3):219-25. Di Renzo GC, Conry JA, Blake J, DeFrancesco MS, DeNicola N, Martin JN, McCue KA, Richmond D, Shah A, Sutton P, Woodruff TJ, van der Poel SZ, Giudice LC. PMID: 26433469; PMCID: PMC6663094.
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    84. Infertility and reproductive disorders: impact of hormonal and inflammatory mechanisms on pregnancy outcome. Hum Reprod Update. 2016 Jan-Feb; 22(1):104-15. Vannuccini S, Clifton VL, Fraser IS, Taylor HS, Critchley H, Giudice LC, Petraglia F. PMID: 26395640; PMCID: PMC7289323.
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    85. Manufacturing doubt about endocrine disrupter science--A rebuttal of industry-sponsored critical comments on the UNEP/WHO report "State of the Science of Endocrine Disrupting Chemicals 2012". Regul Toxicol Pharmacol. 2015 Dec; 73(3):1007-17. Bergman Å, Becher G, Blumberg B, Bjerregaard P, Bornman R, Brandt I, Casey SC, Frouin H, Giudice LC, Heindel JJ, Iguchi T, Jobling S, Kidd KA, Kortenkamp A, Lind PM, Muir D, Ochieng R, Ropstad E, Ross PS, Skakkebaek NE, Toppari J, Vandenberg LN, Woodruff TJ, Zoeller RT. PMID: 26239693.
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    86. Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study. PLoS One. 2015; 10(7):e0129769. Smith-McCune K, Chen JC, Greenblatt RM, Shanmugasundaram U, Shacklett BL, Hilton JF, Johnson B, Irwin JC, Giudice LC. PMID: 26177352; PMCID: PMC4503751.
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    87. Update on Biomarkers for the Detection of Endometriosis. Biomed Res Int. 2015; 2015:130854. Fassbender A, Burney RO, O DF, D'Hooghe T, Giudice L. PMID: 26240814; PMCID: PMC4512573.
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    88. Reducing low-value care in endometriosis between limited evidence and unresolved issues: a proposal. Hum Reprod. 2015 Sep; 30(9):1996-2004. Vercellini P, Giudice LC, Evers JL, Abrao MS. PMID: 26141710.
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    89. Krüppel-Like Factor 13 Deficiency in Uterine Endometrial Cells Contributes to Defective Steroid Hormone Receptor Signaling but Not Lesion Establishment in a Mouse Model of Endometriosis. Biol Reprod. 2015 Jun; 92(6):140. Heard ME, Velarde MC, Giudice LC, Simmen FA, Simmen RC. PMID: 25904015; PMCID: PMC4652611.
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    90. Endometrial stromal fibroblasts from women with polycystic ovary syndrome have impaired progesterone-mediated decidualization, aberrant cytokine profiles and promote enhanced immune cell migration in vitro. Hum Reprod. 2015 May; 30(5):1203-15. Piltonen TT, Chen JC, Khatun M, Kangasniemi M, Liakka A, Spitzer T, Tran N, Huddleston H, Irwin JC, Giudice LC. PMID: 25750105; PMCID: PMC4400200.
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    91. Progestin-Containing Contraceptives Alter Expression of Host Defense-Related Genes of the Endometrium and Cervix. Reprod Sci. 2015 Jul; 22(7):814-28. Goldfien GA, Barragan F, Chen J, Takeda M, Irwin JC, Perry J, Greenblatt RM, Smith-McCune KK, Giudice LC. PMID: 25634912; PMCID: PMC4565478.
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    165. Environmental exposures and adverse pregnancy outcomes: a review of the science. Reprod Sci. 2008 Sep; 15(7):631-50. Stillerman KP, Mattison DR, Giudice LC, Woodruff TJ. PMID: 18836129.
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    166. Controlled ovarian stimulation induces a functional genomic delay of the endometrium with potential clinical implications. J Clin Endocrinol Metab. 2008 Nov; 93(11):4500-10. Horcajadas JA, Mínguez P, Dopazo J, Esteban FJ, Domínguez F, Giudice LC, Pellicer A, Simón C. PMID: 18697870.
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    167. VEGF blockade inhibits angiogenesis and reepithelialization of endometrium. FASEB J. 2008 Oct; 22(10):3571-80. Fan X, Krieg S, Kuo CJ, Wiegand SJ, Rabinovitch M, Druzin ML, Brenner RM, Giudice LC, Nayak NR. PMID: 18606863; PMCID: PMC2537439.
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    169. Extended-release metformin does not reduce the clomiphene citrate dose required to induce ovulation in polycystic ovary syndrome. J Clin Endocrinol Metab. 2008 Aug; 93(8):3124-7. Cataldo NA, Barnhart HX, Legro RS, Myers ER, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Gosman G, Nestler JE, Giudice LC, Reproductive Medicine Network. PMID: 18505764; PMCID: PMC2515084.
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    177. The influence of hydrosalpinx on markers of endometrial receptivity. Semin Reprod Med. 2007 Nov; 25(6):476-82. Savaris RF, Giudice LC. PMID: 17960532.
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    187. Endometrium in PCOS: Implantation and predisposition to endocrine CA. Best Pract Res Clin Endocrinol Metab. 2006 Jun; 20(2):235-44. Giudice LC. PMID: 16772154.
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    202. Proteinase inhibition by proform of eosinophil major basic protein (pro-MBP) is a multistep process of intra- and intermolecular disulfide rearrangements. J Biol Chem. 2005 Mar 18; 280(11):9823-32. Glerup S, Boldt HB, Overgaard MT, Sottrup-Jensen L, Giudice LC, Oxvig C. PMID: 15647258.
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    242. Human placental trophoblasts secrete a disintegrin metalloproteinase very similar to the insulin-like growth factor binding protein-3 protease in human pregnancy serum. Endocrinology. 2000 Feb; 141(2):666-74. Irwin JC, Suen LF, Cheng BH, Martin R, Cannon P, Deal CL, Giudice LC. PMID: 10650948.
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    252. Insulin-like growth factor-II mediates the steroidogenic and growth promoting actions of follicle stimulating hormone on human ovarian pre-antral follicles cultured in vitro. J Clin Endocrinol Metab. 1999 Apr; 84(4):1479-82. Yuan W, Giudice LC. PMID: 10199799.
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    255. Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts. Cancer Res. 1998 Sep 15; 58(18):4168-72. Ulaner GA, Hu JF, Vu TH, Giudice LC, Hoffman AR. PMID: 9751630.
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    260. Human granulosa cells use high density lipoprotein cholesterol for steroidogenesis. J Clin Endocrinol Metab. 1998 Mar; 83(3):983-91. Azhar S, Tsai L, Medicherla S, Chandrasekher Y, Giudice L, Reaven E. PMID: 9506760.
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    311. Local anesthesia with conscious sedation for laparoscopic intrafallopian transfer. Fertil Steril. 1992 Dec; 58(6):1240-2. Milki AA, Hardy RI, el Danasouri I, Giudice LC, Lamb EJ. PMID: 1459278.
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    312. Measurement and characterization of insulin-like growth factor binding protein-3 in human biological fluids: discrepancies between radioimmunoassay and ligand blotting. Endocrinology. 1992 Dec; 131(6):3051-60. Gargosky SE, Pham HM, Wilson KF, Liu F, Giudice LC, Rosenfeld RG. PMID: 1280211.
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    313. Insulin-like growth factors and ovarian follicular development. Endocr Rev. 1992 Nov; 13(4):641-69. Giudice LC. PMID: 1281087.
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    314. Steroid and peptide regulation of insulin-like growth factor-binding proteins secreted by human endometrial stromal cells is dependent on stromal differentiation. J Clin Endocrinol Metab. 1992 Nov; 75(5):1235-41. Giudice LC, Dsupin BA, Irwin JC. PMID: 1385468.
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    315. Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma. J Clin Endocrinol Metab. 1992 Oct; 75(4):1046-53. Cohen P, Graves HC, Peehl DM, Kamarei M, Giudice LC, Rosenfeld RG. PMID: 1383255.
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    316. Insulin-like growth factor binding protein profiles in human ovarian follicular fluid correlate with follicular functional status. J Clin Endocrinol Metab. 1992 Apr; 74(4):821-9. Cataldo NA, Giudice LC. PMID: 1372322.
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    317. Follicular fluid insulin-like growth factor binding protein profiles in polycystic ovary syndrome. J Clin Endocrinol Metab. 1992 Mar; 74(3):695-7. Cataldo NA, Giudice LC. PMID: 1371292.
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    318. Identification of insulin-like growth factor binding proteins in human oviduct. Fertil Steril. 1992 Feb; 57(2):294-301. Giudice LC, Dsupin BA, Irwin JC, Eckert RL. PMID: 1370941.
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    319. Maternal insulin-like growth factor-binding protein messenger ribonucleic acid during rat pregnancy. Endocrinology. 1991 Dec; 129(6):3359-66. Donovan SM, Giudice LC, Murphy LJ, Hintz RL, Rosenfeld RG. PMID: 1720094.
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    320. Human granulosa contain messenger ribonucleic acids encoding insulin-like growth factor-binding proteins (IGFBPs) and secrete IGFBPs in culture. Fertil Steril. 1991 Sep; 56(3):475-80. Giudice LC, Milki AA, Milkowski DA, el Danasouri I. PMID: 1716597.
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    321. A simple assay for proteolysis of IGFBP-3. J Clin Endocrinol Metab. 1991 Jun; 72(6):1391-3. Lamson G, Giudice LC, Rosenfeld RG. PMID: 1709177.
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    322. Characterization of the steroid-dependence of insulin-like growth factor-binding protein-2 synthesis and mRNA expression in cultured human endometrial stromal cells. Hum Reprod. 1991 May; 6(5):632-40. Giudice LC, Milkowski DA, Fielder PJ, Irwin JC. PMID: 1719019.
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    323. Insulin-like growth factor binding proteins in human endometrium: steroid-dependent messenger ribonucleic acid expression and protein synthesis. J Clin Endocrinol Metab. 1991 Apr; 72(4):779-87. Giudice LC, Milkowski DA, Lamson G, Rosenfeld RG, Irwin JC. PMID: 1706350.
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    324. Insulin-like growth factor-II (IGF-II) and IGF binding proteins in human endometrium. Ann N Y Acad Sci. 1991; 626:295-307. Giudice LC, Lamson G, Rosenfeld RG, Irwin JC. PMID: 1711826.
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    325. Insulin-like growth factor binding proteins: structural and molecular relationships. Growth Factors. 1991; 5(1):19-28. Lamson G, Giudice LC, Rosenfeld RG. PMID: 1722987.
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    326. Clinical aspects of insulin-like growth factor binding proteins. Acta Endocrinol (Copenh). 1991; 124 Suppl 2:74-85. Cohen P, Fielder PJ, Hasegawa Y, Frisch H, Giudice LC, Rosenfeld RG. PMID: 1713010.
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    327. Identification of insulin-like growth factor-binding protein-3 (IGFBP-3) and IGFBP-2 in human follicular fluid. J Clin Endocrinol Metab. 1990 Nov; 71(5):1330-8. Giudice LC, Farrell EM, Pham H, Rosenfeld RG. PMID: 1699963.
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    328. Insulin-like growth factor binding proteins in maternal serum throughout gestation and in the puerperium: effects of a pregnancy-associated serum protease activity. J Clin Endocrinol Metab. 1990 Oct; 71(4):806-16. Giudice LC, Farrell EM, Pham H, Lamson G, Rosenfeld RG. PMID: 1698200.
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    329. Identification of insulin-like growth factor-binding protein-2 (IGF-BP-2) and a low molecular weight IGF-BP in human seminal plasma. J Clin Endocrinol Metab. 1990 Feb; 70(2):551-3. Rosenfeld RG, Pham H, Oh Y, Lamson G, Giudice LC. PMID: 1688870.
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    330. Insulinlike growth factor-binding proteins. Recent Prog Horm Res. 1990; 46:99-159; discussion 159-63. Rosenfeld RG, Lamson G, Pham H, Oh Y, Conover C, De Leon DD, Donovan SM, Ocrant I, Giudice L. PMID: 1704143.
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    331. Expression of two insulin-like growth factor-binding proteins in a human endometrial cancer cell line: structural, immunological, and genetic characterization. J Clin Endocrinol Metab. 1989 Oct; 69(4):852-9. Lamson G, Oh Y, Pham H, Giudice LC, Rosenfeld RG. PMID: 2550507.
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    332. Cryopreservation of embryos and ova. Fertil Steril. 1988 May; 49(5):743-64. Friedler S, Giudice LC, Lamb EJ. PMID: 3282929.
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    333. Angiographic arterial embolization to control hemorrhage in abdominal pregnancy: a case report. Obstet Gynecol. 1988 Mar; 71(3 Pt 2):456-9. Kivikoski AI, Martin C, Weyman P, Picus D, Giudice L. PMID: 3347434.
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    334. Pregnancy following nonsurgical donor ovum transfer to a functionally agonadal woman. Fertil Steril. 1987 Aug; 48(2):324-5. Sauer MV, Macaso TM, Ishida EH, Giudice L, Marshall JR, Buster JE. PMID: 3609344.
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    335. Clinical results of Stanford University's in vitro fertilization and embryo transfer program. J In Vitro Fert Embryo Transf. 1987 Jun; 4(3):188-9. Lamb EJ, Polansky F, Milki A, Giudice LC, Friedler S, Wu T, Shen E, Turner K, Ho L. PMID: 3611930.
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    336. Serum levels of CA-125 in patients with endometriosis: a preliminary report. Fertil Steril. 1986 Jun; 45(6):876-8. Giudice LC, Jacobs A, Pineda J, Bell CE, Lippmann L. PMID: 3458595.
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    337. The function of the common subunit of glycoprotein hormones. Biochem Soc Trans. 1978; 6(1):57-60. Pierce JG, Bloomfield GA, Giudice LC. PMID: 640204.
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    338. Separation of functional and non-functional beta subunits of thyrotropin preparations by polyacrylamide gel electrophoresis. Endocrinology. 1977 Sep; 101(3):776-81. Giudice LC, Pierce JG. PMID: 408127.
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    339. Studies on the disulfide bonds of glycoprotein hormones. Course of reduction of bovine luteinizing hormone, bovine thyroid-stimulating hormone, and their subunits. J Biol Chem. 1976 Oct 25; 251(20):6388-91. Pierce JG, Giudice LC, Reeve JR. PMID: 988020.
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    340. Studies on the disulfide bonds of glycoprotein hormones. Complete reduction and reoxidation of the disulfide bonds of the alpha subunit of bovine luteinizing hormone. J Biol Chem. 1976 Oct 25; 251(20):6392-9. Giudice LC, Pierce JG. PMID: 988021.
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    341. Structure and structure-function relationships in glycoprotein hormones. Ciba Found Symp. 1976; 41:225-50. Pierce JG, Faith MR, Giudice LC, Reeve JR. PMID: 780075.
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