Peder Larson, PhD

Title(s)Professor, Radiology
SchoolSchool of Medicine
Address1700 4th St, #102C
San Francisco CA 94158
Phone415-514-4876
ORCID ORCID Icon0000-0003-4183-3634 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Stanford UniversityBS2002Electrical Engineering & Mathematics
    Stanford UniversityMS2003Electrical Engineering
    Stanford UniversityPhD2007Electrical Engineering
    University of California, San FranciscoPostdoctoral Scholar2011Radiology and Biomedical Imaging
    Collapse Awards and Honors
    Magnetic Resonance in Medicine2023Editor's Pick "MoCoLoR for simultaneous structural and functional UTE Lung MRI"
    UCSF Office of Diversity & Outreach2021Chancellor Award for Disability Service
    Medical Imaging with Deep Learning (MIDL)2021Best Long Oral Presentation "Understanding and Visualizing Generalization in Unets"
    Magnetic Resonance in Medicine2020Editor's Pick "Iterative motion-compensation reconstruction UTE for free-breathing pulmonary MRI"
    Magnetic Resonance in Medicine2020Editor's Pick "Extreme MRI: Large-scale volumetric dynamic imaging from continuous acquisitions"
    Academy for Radiology & Biomedical Imaging Research2019Distinguished Investigator
    Magnetic Resonance in Medicine2018Editors Pick "In vivo characterization of brain ultrashort-T2 components"
    American Cancer Society2018Research Scholar
    International Society for Magnetic Resonance in Medicine2011Junior Fellow
    University of California, San Francisco2011Surbeck Scholar Award, 1st place

    Collapse Overview 
    Collapse Overview
    Peder Larson, PhD, is a Professor in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. He is also the Director of the Body Imaging Research Group and a co-Leader of the Hyperpolarized MRI Technology Resource Center. Dr. Larson's research program includes a range of imaging technology development targeting improved clinical outcomes, with projects on metabolic MRI, lung MRI, myelin imaging, PET/MRI, and radiation therapy planning:

    Metabolic imaging methods using hyperpolarized carbon-13 MRI
    This technology uses non-toxic, non-ionizing contrast agents to provide unique metabolism information, and is currently in clinical trials. Our team develops data acquisition, image reconstruction, and data analysis methods for this technology for a broad range of collaborators and applications. We are also leading new patient studies of this technology in renal cancers and heart disease.

    Lung MRI
    Conventional MRI performs very poorly in the lungs but our team has developed methods based on ultrashort echo time (UTE) MRI to provide high quality, high-resolution lung MRI. We are pursuing development of functional imaging biomarkers and translation onto clinical MRI scanners, with a focus on pediatric studies to reduce radiation dose compared to CT.

    Myelin MRI
    Our team has pioneered a new MRI approach for direct imaging of myelin based on ultrashort echo time (UTE) MRI. Other MRI methods provide indirect myelin measurements based measurements on nearby water. We are continuing to develop this technique as a quantitative imaging method, and translating into studies evaluating myelination in disease.

    PET/MRI
    Hybrid PET/MRI systems combine the functional information from PET tracers with the soft-tissue contrast from MRI. Our team is working on PET/MRI technology developments for motion management, quantitative imaging, and multi-modal data analysis with this modality.

    Radiation Therapy PLanning
    Applications of MRI in radiotherapy have increased significantly over the past decade due to the high level of soft tissue provided, often allowing for better visualization of tumors and organs at risk versus computed tomography (CT). Our team is working to develop specialized MR techniques to accurately estimate parameters used for radiotherapy dose calculation as a critical step towards MRI-only treatment planning.


    Dr. Larson is an active member of International Society for Magnetic Resonance in Medicine, the Institute for Electrical and Electronics Engineering, the UC Berkeley and UCSF Graduate Group in Bioengineering, the California Institute for Quantitative Biosciences, and the Bakar Computational Health Sciences Institute.
    Collapse In The News

    Collapse Research 
    Collapse Research Activities and Funding
    UTE MRI: a Novel Biomarker for Remyelination in Multiple Sclerosis Patients
    DOD MS200272Aug 1, 2021 - Jul 31, 2024
    Role: Principal Investigator
    Hyperpolarized 13C Metabolic MRI for Noninvasive Monitoring of Kidney Injury
    NIH R21DK130002Jul 12, 2021 - Apr 30, 2023
    Role: Principal Investigator
    Hyperpolarized C-13 MRI Techniques to Monitor Radiation Therapy Response in Prostate Cancer Patients
    NIH R01CA238379Jul 1, 2021 - Jun 30, 2026
    Role: Co-Investigator
    Ultra-Fast Knee MRI with Deep Learning
    NIH R01AR078762Apr 1, 2021 - Mar 31, 2026
    Role: Co-Investigator
    Translating Hyperpolarized 13C Metabolic MRI to Predict Renal Tumor Aggressiveness
    NIH R01CA249909Jan 1, 2021 - Dec 31, 2025
    Role: Co-Principal Investigator
    Measuring Metabolic Activity in Prostate Cancer Bone Metastases Using Hyperpolarized 13C Pyruvate MRI for Improved Targeted Therapy Monitoring
    NIH R01CA256740Dec 1, 2020 - Nov 30, 2025
    Role: Co-Investigator
    Multi-modal and Extreme PET/MRI Reconstruction Methods
    NIH F32EB030411Dec 1, 2020 - Nov 30, 2022
    Role: Co-Investigator
    Co-Clinical Quantitative Imaging of Small Cell Neuroendocrine Prostate Cancer Using Hyperpolarized 13C MRI
    NIH U24CA253377Sep 7, 2020 - Aug 31, 2025
    Role: Co-Investigator
    Comprehensive Assessment of Cardiac Anatomy and Function with Magnetic Resonance Imaging
    American Heart Association Postdoctoral Fellowship Jan 1, 2020 - Dec 31, 2021
    Role: Mentor
    Development of Sodium Fluoride PET-MRI for Quantitative Assessment of Knee Osteoarthritis
    NIH R01AR074492Aug 16, 2019 - Jun 30, 2024
    Role: Co-Investigator
    Prediction of Clinically Significant Prostate Cancer from Only T2 Weighted Imaging Using Machine Learning
    RSNA Research Resident/Fellow Grant Jul 1, 2019 - Jun 30, 2021
    Role: Co-investigator
    Development and Translation of Hyperpolarized C-13 Prostate Cancer MRI Methods
    NIH U01EB026412Jun 1, 2019 - Feb 29, 2024
    Role: Co-Investigator
    Hyperpolarized C-13 MRI for Early Detection of Aggressive Prostate Cancer in Active Surveillance Patients
    NIH U01CA232320Apr 11, 2019 - Mar 31, 2024
    Role: Co-Investigator
    Prediction of clinically significant prostate cancer and prostate-cancer related outcomes from only T2 weighted imaging using machine learning
    Society for Abdominal Radiology Apr 1, 2019 - Mar 30, 2021
    Role: Co-investigator
    Imaging Metabolism and Cellular Transport in Cancer
    American Cancer Society 131715-RSG-18-005-01-CCEJul 1, 2018 - Jun 30, 2022
    Role: Principal Investigator
    MRI methods for high resolution imaging of the lung
    NIH R01HL136965Apr 15, 2018 - Mar 31, 2022
    Role: Principal Investigator
    Qualification and Harmonization of PET/MRI for Cancer Clinical Trials
    NIH R01CA212148Mar 6, 2017 - Feb 28, 2023
    Role: Co-Investigator
    CLINICAL TRANSLATION OF HYPERPOLARIZED 13C-UREA FOR CANCER MR MOLECULAR IMAGING
    NIH R01CA214554Mar 6, 2017 - Feb 28, 2022
    Role: Co-Investigator
    Multi-Site Development & Evaluation of a Quantitative 3D Hyperpolarized C-13 MRI Clinical Prostate Cancer Exam
    NIH R01CA211150Mar 1, 2017 - Feb 28, 2022
    Role: Co-Investigator
    Metabolic Imaging of Brain Tumor Response to Therapy
    NIH R01CA197254Apr 1, 2016 - Mar 31, 2021
    Role: Co-Investigator
    Hyperpolarized MRI Technology Resource Center
    NIH P41EB013598Jul 1, 2011 - May 31, 2021
    Role: Co-Investigator
    Training Program in Translational Brain Tumor Research
    NIH T32CA151022Sep 1, 2010 - Aug 31, 2025
    Role: Co-Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mixed Supervision of Histopathology Improves Prostate Cancer Classification from MRI. IEEE Trans Med Imaging. 2024 Mar 28; PP. Rajagopal A, Westphalen AC, Velarde N, Simko JP, Nguyen H, Hope TA, Larson PEZ, Magudia K. PMID: 38547000.
      View in: PubMed   Mentions:    Fields:    
    2. 3D balanced SSFP UTE MRI for multiple contrasts whole brain imaging. Magn Reson Med. 2024 Mar 25. Shen X, Caverzasi E, Yang Y, Liu X, Green A, Henry RG, Emir U, Larson PEZ. PMID: 38525680.
      View in: PubMed   Mentions:    Fields:    
    3. Current methods for hyperpolarized [1-13 C]pyruvate MRI human studies. Magn Reson Med. 2024 Mar 05. Larson PEZ, Bernard JML, Bankson JA, Bøgh N, Bok RA, Chen AP, Cunningham CH, Gordon JW, Hövener JB, Laustsen C, Mayer D, McLean MA, Schilling F, Slater JB, Vanderheyden JL, von Morze C, Vigneron DB, Xu D, HP 13C MRI Consensus Group. PMID: 38441968.
      View in: PubMed   Mentions:    Fields:    
    4. Scan-specific Self-supervised Bayesian Deep Non-linear Inversion for Undersampled MRI Reconstruction. IEEE Trans Med Imaging. 2024 Feb 09; PP. Leynes AP, Deveshwar N, Nagarajan SS, Larson PEZ. PMID: 38335079.
      View in: PubMed   Mentions:    Fields:    
    5. Quantification of the in vivo brain ultrashort-T2* component in healthy volunteers. Magn Reson Med. 2024 Jun; 91(6):2417-2430. Deveshwar N, Yao J, Han M, Dwork N, Shen X, Ljungberg E, Caverzasi E, Cao P, Henry R, Green A, Larson PEZ. PMID: 38291598.
      View in: PubMed   Mentions:    Fields:    
    6. Advanced Hyperpolarized 13C Metabolic Imaging Protocol for Patients with Gliomas: A Comprehensive Multimodal MRI Approach. Cancers (Basel). 2024 Jan 13; 16(2). Autry AW, Vaziri S, Gordon JW, Chen HY, Kim Y, Dang D, LaFontaine M, Noeske R, Bok R, Villanueva-Meyer JE, Clarke JL, Oberheim Bush NA, Chang SM, Xu D, Lupo JM, Larson PEZ, Vigneron DB, Li Y. PMID: 38254844; PMCID: PMC10814348.
      View in: PubMed   Mentions:
    7. Hyperpolarized 13 C metabolic imaging of the human abdomen with spatiotemporal denoising. Magn Reson Med. 2024 Jan 09. Nickles TM, Kim Y, Lee PM, Chen HY, Ohliger M, Bok RA, Wang ZJ, Larson PEZ, Vigneron DB, Gordon JW. PMID: 38193310.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Regional quantification of cardiac metabolism with hyperpolarized [1-13C]-pyruvate CMR evaluated in an oral glucose challenge. J Cardiovasc Magn Reson. 2023 Dec 14; 25(1):77. Larson PEZ, Tang S, Liu X, Sinha A, Dwork N, Sivalokanathan S, Liu J, Bok R, Ordovas KG, Slater J, Gordon JW, Abraham MR. PMID: 38093285; PMCID: PMC10720165.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Probing human heart TCA cycle metabolism and response to glucose load using hyperpolarized [2-13 C]pyruvate MRS. NMR Biomed. 2024 Mar; 37(3):e5074. Chen HY, Gordon JW, Dwork N, Chung BT, Riselli A, Sivalokanathan S, Bok RA, Slater JB, Vigneron DB, Abraham MR, Larson PEZ. PMID: 38054254.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    10. Hyperpolarized 13 C Metabolic MRI of Patients with Pancreatic Ductal Adenocarcinoma. J Magn Reson Imaging. 2023 Dec 02. Gordon JW, Chen HY, Nickles T, Lee PM, Bok R, Ohliger MA, Okamoto K, Ko AH, Larson PEZ, Wang ZJ. PMID: 38041836.
      View in: PubMed   Mentions:    Fields:    
    11. Dynamic T2* relaxometry of hyperpolarized [1-13 C]pyruvate MRI in the human brain and kidneys. Magn Reson Med. 2024 Mar; 91(3):1030-1042. Liu X, Cui D, Xu D, Bok R, Wang ZJ, Vigneron DB, Larson PEZ, Gordon JW. PMID: 38013217; PMCID: PMC10872504.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Current Methods for Hyperpolarized [1-13C]pyruvate MRI Human Studies. ArXiv. 2023 Nov 22. Larson PE, Bernard JM, Bankson JA, Bøgh N, Bok RA, Chen AP, Cunningham CH, Gordon J, Hövener JB, Laustsen C, Mayer D, McLean MA, Schilling F, Slater J, Vanderheyden JL, von Morze C, Vigneron DB, Xu D, HP 13C MRI Consensus Group. PMID: 37731660; PMCID: PMC10508833.
      View in: PubMed   Mentions:
    13. Clinically Translatable Hyperpolarized 13C Bicarbonate pH Imaging Method for Use in Prostate Cancer. ACS Sens. 2023 11 24; 8(11):4042-4054. Mu C, Liu X, Kim Y, Riselli A, Korenchan DE, Bok RA, Delos Santos R, Sriram R, Qin H, Nguyen H, Gordon JW, Slater J, Larson PEZ, Vigneron DB, Kurhanewicz J, Wilson DM, Flavell RR. PMID: 37878761; PMCID: PMC10683509.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    14. Pulmonary Ventilation Analysis Using 1H Ultra-Short Echo Time (UTE) Lung MRI: A Reproducibility Study. bioRxiv. 2023 Oct 25. Tan F, Zhu X, Chan M, Deveshwar N, Willmering MM, Lustig M, Larson PEZ. PMID: 37961357; PMCID: PMC10634712.
      View in: PubMed   Mentions:
    15. Probing Human Heart TCA Cycle Metabolism and Response to Glucose Load using Hyperpolarized [2-13C]Pyruvate MR Spectroscopy. medRxiv. 2023 Oct 19. Chen HY, Gordon JW, Dwork N, Chung BT, Riselli A, Sivalokanathan S, Bok RA, Slater JB, Vigneron DB, Abraham MR, Larson PEZ. PMID: 37905131; PMCID: PMC10615004.
      View in: PubMed   Mentions:
    16. Regional quantification of cardiac metabolism with hyperpolarized [1-13C]-pyruvate MRI evaluated in an oral glucose challenge. medRxiv. 2023 Oct 19. Larson PEZ, Tang S, Liu X, Sinha A, Dwork N, Sivalokanathan S, Liu J, Bok R, Ordovas KG, Slater J, Gordon JW, Abraham MR. PMID: 37904936; PMCID: PMC10615005.
      View in: PubMed   Mentions:
    17. Investigating cerebral perfusion with high resolution hyperpolarized [1-13 C]pyruvate MRI. Magn Reson Med. 2023 12; 90(6):2233-2241. Hu JY, Vaziri S, Bøgh N, Kim Y, Autry AW, Bok RA, Li Y, Laustsen C, Xu D, Larson PEZ, Chang S, Vigneron DB, Gordon JW. PMID: 37665726; PMCID: PMC10543485.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Hyperpolarized [2-13C]pyruvate MR molecular imaging with whole brain coverage. Neuroimage. 2023 10 15; 280:120350. Chung BT, Kim Y, Gordon JW, Chen HY, Autry AW, Lee PM, Hu JY, Tan CT, Suszczynski C, Chang SM, Villanueva-Meyer JE, Bok RA, Larson PEZ, Xu D, Li Y, Vigneron DB. PMID: 37634883; PMCID: PMC10530049.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Atlas-Based Adaptive Hadamard-Encoded MR Spectroscopic Imaging at 3T. Tomography. 2023 08 23; 9(5):1592-1602. Liu H, Autry AW, Larson PEZ, Xu D, Li Y. PMID: 37736980; PMCID: PMC10514830.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Multi-parametric hyperpolarized 13C/1H imaging reveals Warburg-related metabolic dysfunction and associated regional heterogeneity in high-grade human gliomas. Neuroimage Clin. 2023; 39:103501. Autry AW, Vaziri S, LaFontaine M, Gordon JW, Chen HY, Kim Y, Villanueva-Meyer JE, Molinaro A, Clarke JL, Oberheim Bush NA, Xu D, Lupo JM, Larson PEZ, Vigneron DB, Chang SM, Li Y. PMID: 37611371; PMCID: PMC10470324.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. A metabolite specific 3D stack-of-spirals bSSFP sequence for improved bicarbonate imaging in hyperpolarized [1-13C]Pyruvate MRI. J Magn Reson. 2023 08; 353:107518. Liu X, Tang S, Cui D, Bok RA, Chen HY, Gordon JW, Wang ZJ, Larson PEZ. PMID: 37402333; PMCID: PMC10498937.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    22. Evaluation of major depressive disorder using 7 Tesla phase sensitive neuroimaging before and after mindfulness-based cognitive therapy. J Affect Disord. 2023 08 15; 335:383-391. Jakary A, Lupo JM, Mackin S, Yin A, Murray D, Yang T, Mukherjee P, Larson P, Xu D, Eisendrath S, Luks T, Li Y. PMID: 37192691.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Co-Clinical Imaging Metadata Information (CIMI) for Cancer Research to Promote Open Science, Standardization, and Reproducibility in Preclinical Imaging. Tomography. 2023 05 11; 9(3):995-1009. Moore SM, Quirk JD, Lassiter AW, Laforest R, Ayers GD, Badea CT, Fedorov AY, Kinahan PE, Holbrook M, Larson PEZ, Sriram R, Chenevert TL, Malyarenko D, Kurhanewicz J, Houghton AM, Ross BD, Pickup S, Gee JC, Zhou R, Gammon ST, Manning HC, Roudi R, Daldrup-Link HE, Lewis MT, Rubin DL, Yankeelov TE, Shoghi KI. PMID: 37218941; PMCID: PMC10204428.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    24. Motion-compensated low-rank reconstruction for simultaneous structural and functional UTE lung MRI. Magn Reson Med. 2023 09; 90(3):1101-1113. Tan F, Zhu X, Chan M, Zapala MA, Vasanawala SS, Ong F, Lustig M, Larson PEZ. PMID: 37158318; PMCID: PMC10501714.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Metabolite-Specific Echo Planar Imaging for Preclinical Studies with Hyperpolarized 13C-Pyruvate MRI. Tomography. 2023 03 27; 9(2):736-749. Sahin SI, Ji X, Agarwal S, Sinha A, Mali I, Gordon JW, Mattingly M, Subramaniam S, Kurhanewicz J, Larson PEZ, Sriram R. PMID: 37104130; PMCID: PMC10143874.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    26. An Online Repository for Pre-Clinical Imaging Protocols (PIPs). Tomography. 2023 03 27; 9(2):750-758. Gammon ST, Cohen AS, Lehnert AL, Sullivan DC, Malyarenko D, Manning HC, Hormuth DA, Daldrup-Link HE, An H, Quirk JD, Shoghi K, Pagel MD, Kinahan PE, Miyaoka RS, Houghton AM, Lewis MT, Larson P, Sriram R, Blocker SJ, Pickup S, Badea A, Badea CT, Yankeelov TE, Chenevert TL. PMID: 37104131; PMCID: PMC10145184.
      View in: PubMed   Mentions: 2     Fields:    
    27. Optimization in the space domain for density compensation with the nonuniform FFT. Magn Reson Imaging. 2023 07; 100:102-111. Dwork N, O'Connor D, Johnson EMI, Baron CA, Gordon JW, Pauly JM, Larson PEZ. PMID: 36934830; PMCID: PMC10288563.
      View in: PubMed   Mentions: 1     Fields:    
    28. Synthesizing Complex-Valued Multicoil MRI Data from Magnitude-Only Images. Bioengineering (Basel). 2023 Mar 14; 10(3). Deveshwar N, Rajagopal A, Sahin S, Shimron E, Larson PEZ. PMID: 36978749; PMCID: PMC10045391.
      View in: PubMed   Mentions: 1  
    29. Federated Learning with Research Prototypes: Application to Multi-Center MRI-based Detection of Prostate Cancer with Diverse Histopathology. Acad Radiol. 2023 04; 30(4):644-657. Rajagopal A, Redekop E, Kemisetti A, Kulkarni R, Raman S, Sarma K, Magudia K, Arnold CW, Larson PEZ. PMID: 36914501; PMCID: PMC10869141.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Evaluation of Apparent Diffusion Coefficient Repeatability and Reproducibility for Preclinical MRIs Using Standardized Procedures and a Diffusion-Weighted Imaging Phantom. Tomography. 2023 02 07; 9(1):375-386. Malyarenko D, Amouzandeh G, Pickup S, Zhou R, Manning HC, Gammon ST, Shoghi KI, Quirk JD, Sriram R, Larson P, Lewis MT, Pautler RG, Kinahan PE, Muzi M, Chenevert TL. PMID: 36828382; PMCID: PMC9964373.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    31. Synthetic PET via Domain Translation of 3-D MRI. IEEE Trans Radiat Plasma Med Sci. 2023 Apr; 7(4):333-343. Rajagopal A, Natsuaki Y, Wangerin K, Hamdi M, An H, Sunderland JJ, Laforest R, Kinahan PE, Larson PEZ, Hope TA. PMID: 37396797; PMCID: PMC10311993.
      View in: PubMed   Mentions: 2  
    32. A 13C/31P surface coil to visualize metabolism and energetics in the rodent brain at 3 Tesla. J Magn Reson. 2022 10; 343:107286. Vaidya MV, Zhang B, Hong D, Brown R, Batsios G, Viswanath P, Paska J, Wulf G, Grant AK, Ronen SM, Larson PEZ. PMID: 36075133; PMCID: PMC9721620.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    33. Assessment of higher-order singular value decomposition denoising methods on dynamic hyperpolarized [1-13C]pyruvate MRI data from patients with glioma. Neuroimage Clin. 2022; 36:103155. Vaziri S, Autry AW, Lafontaine M, Kim Y, Gordon JW, Chen HY, Hu JY, Lupo JM, Chang SM, Clarke JL, Villanueva-Meyer JE, Bush NAO, Xu D, Larson PEZ, Vigneron DB, Li Y. PMID: 36007439; PMCID: PMC9421383.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    34. Improving multiparametric MR-transrectal ultrasound guided fusion prostate biopsies with hyperpolarized 13 C pyruvate metabolic imaging: A technical development study. Magn Reson Med. 2022 Dec; 88(6):2609-2620. Chen HY, Bok RA, Cooperberg MR, Nguyen HG, Shinohara K, Westphalen AC, Wang ZJ, Ohliger MA, Gebrezgiabhier D, Carvajal L, Gordon JW, Larson PEZ, Aggarwal R, Kurhanewicz J, Vigneron DB. PMID: 35975978; PMCID: PMC9794017.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    35. Generation of synthetic megavoltage CT for MRI-only radiotherapy treatment planning using a 3D deep convolutional neural network. Med Phys. 2022 Oct; 49(10):6622-6634. Scholey JE, Rajagopal A, Vasquez EG, Sudhyadhom A, Larson PEZ. PMID: 35870154; PMCID: PMC9588542.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    36. Kinetic analysis of multi-resolution hyperpolarized 13 C human brain MRI to study cerebral metabolism. Magn Reson Med. 2022 11; 88(5):2190-2197. Hu JY, Kim Y, Autry AW, Frost MM, Bok RA, Villanueva-Meyer JE, Xu D, Li Y, Larson PEZ, Vigneron DB, Gordon JW. PMID: 35754148; PMCID: PMC9420752.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    37. Development of specialized magnetic resonance acquisition techniques for human hyperpolarized [13 C,15 N2 ]urea + [1-13 C]pyruvate simultaneous perfusion and metabolic imaging. Magn Reson Med. 2022 09; 88(3):1039-1054. Liu X, Tang S, Mu C, Qin H, Cui D, Lai YC, Riselli AM, Delos Santos R, Carvajal L, Gebrezgiabhier D, Bok RA, Chen HY, Flavell RR, Gordon JW, Vigneron DB, Kurhanewicz J, Larson PEZ. PMID: 35526263; PMCID: PMC9810116.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    38. Improved accuracy of relative electron density and proton stopping power ratio through CycleGAN machine learning. Phys Med Biol. 2022 05 02; 67(10). Scholey J, Vinas L, Kearney V, Yom S, Larson PEZ, Descovich M, Sudhyadhom A. PMID: 35417903; PMCID: PMC9121765.
      View in: PubMed   Mentions: 1     Fields:    
    39. Whole-Abdomen Metabolic Imaging of Healthy Volunteers Using Hyperpolarized [1-13 C]pyruvate MRI. J Magn Reson Imaging. 2022 12; 56(6):1792-1806. Lee PM, Chen HY, Gordon JW, Wang ZJ, Bok R, Hashoian R, Kim Y, Liu X, Nickles T, Cheung K, Alas FL, Daniel H, Larson PEZ, von Morze C, Vigneron DB, Ohliger MA. PMID: 35420227; PMCID: PMC9562149.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    40. Initial Experience on Hyperpolarized [1-13C]Pyruvate MRI Multicenter Reproducibility-Are Multicenter Trials Feasible? Tomography. 2022 03 01; 8(2):585-595. Bøgh N, Gordon JW, Hansen ESS, Bok RA, Blicher JU, Hu JY, Larson PEZ, Vigneron DB, Laustsen C. PMID: 35314625; PMCID: PMC8938827.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    41. US lesion visibility predicts clinically significant upgrade of prostate cancer by systematic biopsy. Abdom Radiol (NY). 2022 03; 47(3):1133-1141. Velarde N, Westphalen AC, Nguyen HG, Neuhaus J, Shinohara K, Simko JP, Larson PE, Magudia K. PMID: 34997299; PMCID: PMC8863714.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    42. Acquisition and quantification pipeline for in vivo hyperpolarized 13 C MR spectroscopy. Magn Reson Med. 2022 04; 87(4):1673-1687. Hong D, Batsios G, Viswanath P, Gillespie AM, Vaidya M, Larson PEZ, Ronen SM. PMID: 34775639; PMCID: PMC8830804.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    43. Hyperpolarized 1-[13C]-Pyruvate Magnetic Resonance Imaging Detects an Early Metabolic Response to Immune Checkpoint Inhibitor Therapy in Prostate Cancer. Eur Urol. 2022 02; 81(2):219-221. de Kouchkovsky I, Chen HY, Ohliger MA, Wang ZJ, Bok RA, Gordon JW, Larson PEZ, Frost M, Okamoto K, Cooperberg MR, Kurhanewicz J, Vigneron DB, Aggarwal R. PMID: 34758912; PMCID: PMC9275093.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    44. Harmonization of PET image reconstruction parameters in simultaneous PET/MRI. EJNMMI Phys. 2021 Nov 05; 8(1):75. Laforest R, Khalighi M, Natsuaki Y, Rajagopal A, Chandramohan D, Byrd D, An H, Larson P, James SS, Sunderland JJ, Kinahan PE, Hope TA. PMID: 34739621; PMCID: PMC8571452.
      View in: PubMed   Mentions: 1  
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    108. High spatiotemporal resolution bSSFP imaging of hyperpolarized [1-13 C]pyruvate and [1-13 C]lactate with spectral suppression of alanine and pyruvate-hydrate. Magn Reson Med. 2018 09; 80(3):1048-1060. Milshteyn E, von Morze C, Gordon JW, Zhu Z, Larson PEZ, Vigneron DB. PMID: 29451329; PMCID: PMC5980670.
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    109. 3D hyperpolarized C-13 EPI with calibrationless parallel imaging. J Magn Reson. 2018 04; 289:92-99. Gordon JW, Hansen RB, Shin PJ, Feng Y, Vigneron DB, Larson PEZ. PMID: 29476930; PMCID: PMC5856653.
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    110. Development of methods and feasibility of using hyperpolarized carbon-13 imaging data for evaluating brain metabolism in patient studies. Magn Reson Med. 2018 09; 80(3):864-873. Park I, Larson PEZ, Gordon JW, Carvajal L, Chen HY, Bok R, Van Criekinge M, Ferrone M, Slater JB, Xu D, Kurhanewicz J, Vigneron DB, Chang S, Nelson SJ. PMID: 29322616; PMCID: PMC5980662.
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    111. 2018 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP):. Synthetic CT Generation Using MRI with Deep Learning: How Does the Selection of Input Images Affect the Resulting Synthetic CT?. 2018; 6692-6696. Leynes AP, Larson PEZ. View Publication.
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    113. PET/MRI: Where might it replace PET/CT?. Journal of Magnetic Resonance Imaging. 2017 Nov 1; 46(5):spcone-spcone. Ehman EE, Johnson JG, Villanueva-Meyer VJ, Cha CS, Leynes LA, Larson LP, Hope HT. .
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    115. Shuffled magnetization-prepared multicontrast rapid gradient-echo imaging. Magn Reson Med. 2018 Jan; 79(1):62-70. Cao P, Zhu X, Tang S, Leynes A, Jakary A, Larson PEZ. PMID: 29080236; PMCID: PMC5772996.
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    116. Reliable and Reproducible GABA Measurements Using Automated Spectral Prescription at Ultra-High Field. Front Hum Neurosci. 2017; 11:506. Li Y, Bian W, Larson P, Crane JC, Parvathaneni P, Nagarajan S, Nelson SJ. PMID: 29118697; PMCID: PMC5661373.
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    118. Motion robust high resolution 3D free-breathing pulmonary MRI using dynamic 3D image self-navigator. Magn Reson Med. 2018 06; 79(6):2954-2967. Jiang W, Ong F, Johnson KM, Nagle SK, Hope TA, Lustig M, Larson PEZ. PMID: 29023975; PMCID: PMC6474413.
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    121. Assessing Prostate Cancer Aggressiveness with Hyperpolarized Dual-Agent 3D Dynamic Imaging of Metabolism and Perfusion. Cancer Res. 2017 06 15; 77(12):3207-3216. Chen HY, Larson PEZ, Bok RA, von Morze C, Sriram R, Delos Santos R, Delos Santos J, Gordon JW, Bahrami N, Ferrone M, Kurhanewicz J, Vigneron DB. PMID: 28428273; PMCID: PMC5484421.
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    122. Diffusion-weighted imaging of hyperpolarized [13 C]urea in mouse liver. J Magn Reson Imaging. 2018 01; 47(1):141-151. Marco-Rius I, Gordon JW, Mattis AN, Bok R, Delos Santos R, Sukumar S, Larson PEZ, Vigneron DB, Ohliger MA. PMID: 28419644; PMCID: PMC5645231.
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    124. Hybrid ZTE/Dixon MR-based attenuation correction for quantitative uptake estimation of pelvic lesions in PET/MRI. Med Phys. 2017 Mar; 44(3):902-913. Leynes AP, Yang J, Shanbhag DD, Kaushik SS, Seo Y, Hope TA, Wiesinger F, Larson PE. PMID: 28112410; PMCID: PMC5877454.
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    125. Quantitative Evaluation of Atlas-based Attenuation Correction for Brain PET in an Integrated Time-of-Flight PET/MR Imaging System. Radiology. 2017 07; 284(1):169-179. Yang J, Jian Y, Jenkins N, Behr SC, Hope TA, Larson PEZ, Vigneron D, Seo Y. PMID: 28234560.
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    126. Imaging of the rabbit supraspinatus enthesis at 7 Tesla: a 4-week time course after repair surgery and effect of channeling. J Magn Reson Imaging. 2017 08; 46(2):461-467. Trudel G, Melkus G, Cron GO, Louati H, Sheikh A, Larson PEZ, Schweitzer M, Lapner P, Uhthoff HK, Laneuville O. PMID: 28152242.
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    127. Development of high resolution 3D hyperpolarized carbon-13 MR molecular imaging techniques. Magn Reson Imaging. 2017 05; 38:152-162. Milshteyn E, von Morze C, Reed GD, Shang H, Shin PJ, Zhu Z, Chen HY, Bok R, Goga A, Kurhanewicz J, Larson PE, Vigneron DB. PMID: 28077268; PMCID: PMC5360530.
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    128. Monitoring acute metabolic changes in the liver and kidneys induced by fructose and glucose using hyperpolarized [2-13 C]dihydroxyacetone. Magn Reson Med. 2017 01; 77(1):65-73. Marco-Rius I, von Morze C, Sriram R, Cao P, Chang GY, Milshteyn E, Bok RA, Ohliger MA, Pearce D, Kurhanewicz J, Larson PE, Vigneron DB, Merritt M. PMID: 27859575; PMCID: PMC5191913.
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    129. Spectrally selective three-dimensional dynamic balanced steady-state free precession for hyperpolarized C-13 metabolic imaging with spectrally selective radiofrequency pulses. Magn Reson Med. 2017 09; 78(3):963-975. Shang H, Sukumar S, von Morze C, Bok RA, Marco-Rius I, Kerr A, Reed GD, Milshteyn E, Ohliger MA, Kurhanewicz J, Larson PEZ, Pauly JM, Vigneron DB. PMID: 27770458; PMCID: PMC5400740.
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    130. Mis-estimation and bias of hyperpolarized apparent diffusion coefficient measurements due to slice profile effects. Magn Reson Med. 2017 09; 78(3):1087-1092. Gordon JW, Milshteyn E, Marco-Rius I, Ohliger M, Vigneron DB, Larson PEZ. PMID: 27735082; PMCID: PMC5391314.
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    131. Separation of extra- and intracellular metabolites using hyperpolarized (13)C diffusion weighted MR. J Magn Reson. 2016 09; 270:115-123. Koelsch BL, Sriram R, Keshari KR, Leon Swisher C, Van Criekinge M, Sukumar S, Vigneron DB, Wang ZJ, Larson PEZ, Kurhanewicz J. PMID: 27434780; PMCID: PMC5448422.
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    132. Combining hyperpolarized 13 C MRI with a liver-specific gadolinium contrast agent for selective assessment of hepatocyte metabolism. Magn Reson Med. 2017 06; 77(6):2356-2363. Ohliger MA, von Morze C, Marco-Rius I, Gordon J, Larson PEZ, Bok R, Chen HY, Kurhanewicz J, Vigneron D. PMID: 27298073; PMCID: PMC5156580.
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    133. Imaging Renal Urea Handling in Rats at Millimeter Resolution using Hyperpolarized Magnetic Resonance Relaxometry. Tomography. 2016 Jun; 2(2):125-135. Reed GD, von Morze C, Verkman AS, Koelsch BL, Chaumeil MM, Lustig M, Ronen SM, Bok RA, Sands JM, Larson PE, Wang ZJ, Larsen JH, Kurhanewicz J, Vigneron DB. PMID: 27570835; PMCID: PMC4996281.
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    134. Optimizing Flip Angles for Metabolic Rate Estimation in Hyperpolarized Carbon-13 MRI. IEEE Trans Med Imaging. 2016 11; 35(11):2403-2412. Maidens J, Gordon JW, Arcak M, Larson PE. PMID: 27249825; PMCID: PMC5134417.
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    135. Accelerated high-bandwidth MR spectroscopic imaging using compressed sensing. Magn Reson Med. 2016 08; 76(2):369-79. Cao P, Shin PJ, Park I, Najac C, Marco-Rius I, Vigneron DB, Nelson SJ, Ronen SM, Larson PE. PMID: 27228088; PMCID: PMC4945498.
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    136. Detection of localized changes in the metabolism of hyperpolarized gluconeogenic precursors 13 C-lactate and 13 C-pyruvate in kidney and liver. Magn Reson Med. 2017 04; 77(4):1429-1437. von Morze C, Chang GY, Larson PE, Shang H, Allu PK, Bok RA, Crane JC, Olson MP, Tan CT, Marco-Rius I, Nelson SJ, Kurhanewicz J, Pearce D, Vigneron DB. PMID: 27098724; PMCID: PMC5074920.
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    137. Detecting Metabolism of Gluconeogenic Precursors Lactate and Pyruvate in Kidney & Liver with Hyperpolarized 13 C MRI. The FASEB Journal. 2016 Apr 1; 30(S1). von Morze vC, Chang CG, Larson LP, Shang SH, Allu AP, Bok BR, Crane CJ, Olson OM, Tan TC, Marco-Rius MI, Nelson NS, Kurhanewicz KJ, Pearce PD, Vigneron VD. .
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    140. Ultrashort echo time and zero echo time MRI at 7T. MAGMA. 2016 Jun; 29(3):359-70. Larson PE, Han M, Krug R, Jakary A, Nelson SJ, Vigneron DB, Henry RG, McKinnon G, Kelley DA. PMID: 26702940; PMCID: PMC4892974.
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    141. Multiband RF pulses with improved performance via convex optimization. J Magn Reson. 2016 Jan; 262:81-90. Shang H, Larson PEZ, Kerr A, Reed G, Sukumar S, Elkhaled A, Gordon JW, Ohliger MA, Pauly JM, Lustig M, Vigneron DB. PMID: 26754063; PMCID: PMC4716678.
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    143. Development and testing of hyperpolarized (13)C MR calibrationless parallel imaging. J Magn Reson. 2016 Jan; 262:1-7. Feng Y, Gordon JW, Shin PJ, von Morze C, Lustig M, Larson PEZ, Ohliger MA, Carvajal L, Tropp J, Pauly JM, Vigneron DB. PMID: 26679288; PMCID: PMC4864033.
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    144. Dynamic contrast-enhanced quantitative susceptibility mapping with ultrashort echo time MRI for evaluating renal function. Am J Physiol Renal Physiol. 2016 Jan 15; 310(2):F174-82. Xie L, Layton AT, Wang N, Larson PE, Zhang JL, Lee VS, Liu C, Johnson GA. PMID: 26447222; PMCID: PMC4719043.
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    145. Application of Good's buffers to pH imaging using hyperpolarized (13)C MRI. Chem Commun (Camb). 2015 Sep 25; 51(74):14119-22. Flavell RR, von Morze C, Blecha JE, Korenchan DE, Van Criekinge M, Sriram R, Gordon JW, Chen HY, Subramaniam S, Bok RA, Wang ZJ, Vigneron DB, Larson PE, Kurhanewicz J, Wilson DM. PMID: 26257040; PMCID: PMC4854286.
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    146. Quantifying temperature-dependent T1 changes in cortical bone using ultrashort echo-time MRI. Magn Reson Med. 2015 Dec; 74(6):1548-55. Han M, Rieke V, Scott SJ, Ozhinsky E, Salgaonkar VA, Jones PD, Larson PE, Diederich CJ, Krug R. PMID: 26390357; PMCID: PMC4715675.
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    147. Detection of Small Pulmonary Nodules with Ultrashort Echo Time Sequences in Oncology Patients by Using a PET/MR System. Radiology. 2016 Jan; 278(1):239-46. Burris NS, Johnson KM, Larson PE, Hope MD, Nagle SK, Behr SC, Hope TA. PMID: 26133050; PMCID: PMC4699498.
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    148. Dynamic UltraFast 2D EXchange SpectroscopY (UF-EXSY) of hyperpolarized substrates. J Magn Reson. 2015 Aug; 257:102-9. Leon Swisher C, Koelsch B, Sukumar S, Sriram R, Santos RD, Wang ZJ, Kurhanewicz J, Vigneron D, Larson P. PMID: 26117655; PMCID: PMC4515769.
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    150. Concentric rings K-space trajectory for hyperpolarized (13)C MR spectroscopic imaging. Magn Reson Med. 2016 Jan; 75(1):19-31. Jiang W, Lustig M, Larson PE. PMID: 25533653; PMCID: PMC4476971.
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    151. Simultaneous imaging of radiation-induced cerebral microbleeds, arteries and veins, using a multiple gradient echo sequence at 7 Tesla. J Magn Reson Imaging. 2015 Aug; 42(2):269-79. Bian W, Banerjee S, Kelly DA, Hess CP, Larson PE, Chang SM, Nelson SJ, Lupo JM. PMID: 25471321; PMCID: PMC4876721.
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    153. Rapid in vivo apparent diffusion coefficient mapping of hyperpolarized (13) C metabolites. Magn Reson Med. 2015 Sep; 74(3):622-633. Koelsch BL, Reed GD, Keshari KR, Chaumeil MM, Bok R, Ronen SM, Vigneron DB, Kurhanewicz J, Larson PEZ. PMID: 25213126; PMCID: PMC4362805.
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    154. Noninvasive in vivo imaging of diabetes-induced renal oxidative stress and response to therapy using hyperpolarized 13C dehydroascorbate magnetic resonance. Diabetes. 2015 Feb; 64(2):344-52. Keshari KR, Wilson DM, Sai V, Bok R, Jen KY, Larson P, Van Criekinge M, Kurhanewicz J, Wang ZJ. PMID: 25187363; PMCID: PMC4303960.
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    155. Magnetic resonance imaging for lung cancer screen. J Thorac Dis. 2014 Sep; 6(9):1340-8. Wang YX, Lo GG, Yuan J, Larson PE, Zhang X. PMID: 25276380; PMCID: PMC4178109.
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    157. Short-echo three-dimensional H-1 MR spectroscopic imaging of patients with glioma at 7 Tesla for characterization of differences in metabolite levels. J Magn Reson Imaging. 2015 May; 41(5):1332-41. Li Y, Larson P, Chen AP, Lupo JM, Ozhinsky E, Kelley D, Chang SM, Nelson SJ. PMID: 24935758; PMCID: PMC4269580.
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    158. Hyperpolarized [1-13C] glutamate: a metabolic imaging biomarker of IDH1 mutational status in glioma. Cancer Res. 2014 Aug 15; 74(16):4247-57. Chaumeil MM, Larson PE, Woods SM, Cai L, Eriksson P, Robinson AE, Lupo JM, Vigneron DB, Nelson SJ, Pieper RO, Phillips JJ, Ronen SM. PMID: 24876103; PMCID: PMC4134724.
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    159. Depiction of achilles tendon microstructure in vivo using high-resolution 3-dimensional ultrashort echo-time magnetic resonance imaging at 7 T. Invest Radiol. 2014 May; 49(5):339-45. Han M, Larson PE, Liu J, Krug R. PMID: 24500089; PMCID: PMC4143127.
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    160. Kinetic and perfusion modeling of hyperpolarized (13)C pyruvate and urea in cancer with arbitrary RF flip angles. Quant Imaging Med Surg. 2014 Feb; 4(1):24-32. Bahrami N, Swisher CL, Von Morze C, Vigneron DB, Larson PE. PMID: 24649432; PMCID: PMC3947982.
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    164. Metabolic imaging of patients with prostate cancer using hyperpolarized [1-¹³C]pyruvate. Sci Transl Med. 2013 Aug 14; 5(198):198ra108. Nelson SJ, Kurhanewicz J, Vigneron DB, Larson PE, Harzstark AL, Ferrone M, van Criekinge M, Chang JW, Bok R, Park I, Reed G, Carvajal L, Small EJ, Munster P, Weinberg VK, Ardenkjaer-Larsen JH, Chen AP, Hurd RE, Odegardstuen LI, Robb FJ, Tropp J, Murray JA. PMID: 23946197; PMCID: PMC4201045.
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    166. Signal scaling improves the signal-to-noise ratio of measurements with segmented 2D-selective radiofrequency excitations. Magn Reson Med. 2013 Dec; 70(6):1491-9. Finsterbusch J, Busch MG, Larson PE. PMID: 23440633; PMCID: PMC4987130.
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    167. Diffusion MR of hyperpolarized 13C molecules in solution. Analyst. 2013 Feb 21; 138(4):1011-4. Koelsch BL, Keshari KR, Peeters TH, Larson PE, Wilson DM, Kurhanewicz J. PMID: 23304699; PMCID: PMC3568999.
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    173. A rapid method for direct detection of metabolic conversion and magnetization exchange with application to hyperpolarized substrates. J Magn Reson. 2012 Dec; 225:71-80. Larson PE, Kerr AB, Swisher CL, Pauly JM, Vigneron DB. PMID: 23143011; PMCID: PMC3531583.
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    174. Frequency-specific SSFP for hyperpolarized ¹³C metabolic imaging at 14.1 T. Magn Reson Imaging. 2013 Feb; 31(2):163-70. von Morze C, Sukumar S, Reed GD, Larson PE, Bok RA, Kurhanewicz J, Vigneron DB. PMID: 22898680; PMCID: PMC3651030.
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    175. A method for simultaneous echo planar imaging of hyperpolarized ¹³C pyruvate and ¹³C lactate. J Magn Reson. 2012 Apr; 217:41-7. Reed GD, Larson PE, Morze Cv, Bok R, Lustig M, Kerr AB, Pauly JM, Kurhanewicz J, Vigneron DB. PMID: 22405760; PMCID: PMC3326401.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    176. Investigating tumor perfusion and metabolism using multiple hyperpolarized (13)C compounds: HP001, pyruvate and urea. Magn Reson Imaging. 2012 Apr; 30(3):305-11. von Morze C, Larson PE, Hu S, Yoshihara HA, Bok RA, Goga A, Ardenkjaer-Larsen JH, Vigneron DB. PMID: 22169407; PMCID: PMC3393100.
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    177. Hyperpolarized 13C dehydroascorbate as an endogenous redox sensor for in vivo metabolic imaging. Proc Natl Acad Sci U S A. 2011 Nov 15; 108(46):18606-11. Keshari KR, Kurhanewicz J, Bok R, Larson PE, Vigneron DB, Wilson DM. PMID: 22042839; PMCID: PMC3219134.
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    178. Generating super stimulated-echoes in MRI and their application to hyperpolarized C-13 diffusion metabolic imaging. IEEE Trans Med Imaging. 2012 Feb; 31(2):265-75. Larson PE, Kerr AB, Reed GD, Hurd RE, Kurhanewicz J, Pauly JM, Vigneron DB. PMID: 22027366; PMCID: PMC3274664.
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    179. In vivo measurement of normal rat intracellular pyruvate and lactate levels after injection of hyperpolarized [1-(13)C]alanine. Magn Reson Imaging. 2011 Oct; 29(8):1035-40. Hu S, Zhu M, Yoshihara HA, Wilson DM, Keshari KR, Shin P, Reed G, von Morze C, Bok R, Larson PE, Kurhanewicz J, Vigneron DB. PMID: 21855243; PMCID: PMC3172390.
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    180. Ultrashort echo time MRI of cortical bone at 7 tesla field strength: a feasibility study. J Magn Reson Imaging. 2011 Sep; 34(3):691-5. Krug R, Larson PE, Wang C, Burghardt AJ, Kelley DA, Link TM, Zhang X, Vigneron DB, Majumdar S. PMID: 21769960; PMCID: PMC3197976.
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    181. 13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression. Cell Metab. 2011 Jul 06; 14(1):131-42. Hu S, Balakrishnan A, Bok RA, Anderton B, Larson PE, Nelson SJ, Kurhanewicz J, Vigneron DB, Goga A. PMID: 21723511; PMCID: PMC3858338.
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    182. Science to practice: Can inflammatory arthritis be monitored by using MR imaging with injected hyperpolarized 13C-pyruvate? Radiology. 2011 May; 259(2):309-10. Larson PE, Gold GE. PMID: 21502386; PMCID: PMC6939944.
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    183. Multi-band frequency encoding method for metabolic imaging with hyperpolarized [1-(13)C]pyruvate. J Magn Reson. 2011 Aug; 211(2):109-13. von Morze C, Reed G, Shin P, Larson PE, Hu S, Bok R, Vigneron DB. PMID: 21596601; PMCID: PMC3143308.
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    184. Imaging of blood flow using hyperpolarized [(13)C]urea in preclinical cancer models. J Magn Reson Imaging. 2011 Mar; 33(3):692-7. von Morze C, Larson PE, Hu S, Keshari K, Wilson DM, Ardenkjaer-Larsen JH, Goga A, Bok R, Kurhanewicz J, Vigneron DB. PMID: 21563254; PMCID: PMC3566235.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    185. Multi-channel metabolic imaging, with SENSE reconstruction, of hyperpolarized [1-(13)C] pyruvate in a live rat at 3.0 tesla on a clinical MR scanner. J Magn Reson. 2011 Jan; 208(1):171-7. Tropp J, Lupo JM, Chen A, Calderon P, McCune D, Grafendorfer T, Ozturk-Isik E, Larson PE, Hu S, Yen YF, Robb F, Bok R, Schulte R, Xu D, Hurd R, Vigneron D, Nelson S. PMID: 21130012; PMCID: PMC3387549.
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    186. Fast dynamic 3D MR spectroscopic imaging with compressed sensing and multiband excitation pulses for hyperpolarized 13C studies. Magn Reson Med. 2011 Mar; 65(3):610-9. Larson PE, Hu S, Lustig M, Kerr AB, Nelson SJ, Kurhanewicz J, Pauly JM, Vigneron DB. PMID: 20939089; PMCID: PMC3021589.
      View in: PubMed   Mentions: 75     Fields:    Translation:Animals
    187. Hyperpolarized 13C spectroscopic imaging informs on hypoxia-inducible factor-1 and myc activity downstream of platelet-derived growth factor receptor. Cancer Res. 2010 Oct 01; 70(19):7400-10. Dafni H, Larson PE, Hu S, Yoshihara HA, Ward CS, Venkatesh HS, Wang C, Zhang X, Vigneron DB, Ronen SM. PMID: 20858719; PMCID: PMC2948586.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    188. Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo. J Magn Reson. 2010 Jul; 205(1):141-7. Wilson DM, Keshari KR, Larson PE, Chen AP, Hu S, Van Criekinge M, Bok R, Nelson SJ, Macdonald JM, Vigneron DB, Kurhanewicz J. PMID: 20478721; PMCID: PMC2885774.
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    189. Investigation of tumor hyperpolarized [1-13C]-pyruvate dynamics using time-resolved multiband RF excitation echo-planar MRSI. Magn Reson Med. 2010 Mar; 63(3):582-91. Larson PE, Bok R, Kerr AB, Lustig M, Hu S, Chen AP, Nelson SJ, Pauly JM, Kurhanewicz J, Vigneron DB. PMID: 20187172; PMCID: PMC2844437.
      View in: PubMed   Mentions: 53     Fields:    Translation:Animals
    190. 3D compressed sensing for highly accelerated hyperpolarized (13)C MRSI with in vivo applications to transgenic mouse models of cancer. Magn Reson Med. 2010 Feb; 63(2):312-21. Hu S, Lustig M, Balakrishnan A, Larson PE, Bok R, Kurhanewicz J, Nelson SJ, Goga A, Pauly JM, Vigneron DB. PMID: 20017160; PMCID: PMC2829256.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimals
    191. Hyperpolarized 13C magnetic resonance metabolic imaging: application to brain tumors. Neuro Oncol. 2010 Feb; 12(2):133-44. Park I, Larson PE, Zierhut ML, Hu S, Bok R, Ozawa T, Kurhanewicz J, Vigneron DB, Vandenberg SR, James CD, Nelson SJ. PMID: 20150380; PMCID: PMC2940577.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimals
    192. Hyperpolarized [2-13C]-fructose: a hemiketal DNP substrate for in vivo metabolic imaging. J Am Chem Soc. 2009 Dec 09; 131(48):17591-6. Keshari KR, Wilson DM, Chen AP, Bok R, Larson PE, Hu S, Van Criekinge M, Macdonald JM, Vigneron DB, Kurhanewicz J. PMID: 19860409; PMCID: PMC2796621.
      View in: PubMed   Mentions: 54     Fields:    Translation:Animals
    193. Anisotropic field-of-view shapes for improved PROPELLER imaging. Magn Reson Imaging. 2009 May; 27(4):470-9. Larson PE, Lustig MS, Nishimura DG. PMID: 18818039; PMCID: PMC2882965.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    194. Multiband excitation pulses for hyperpolarized 13C dynamic chemical-shift imaging. J Magn Reson. 2008 Sep; 194(1):121-7. Larson PE, Kerr AB, Chen AP, Lustig MS, Zierhut ML, Hu S, Cunningham CH, Pauly JM, Kurhanewicz J, Vigneron DB. PMID: 18619875; PMCID: PMC3739981.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    195. IEEE Transactions on Medical Imaging. Anisotropic Field-of-views in radial imaging. 2008; 27(1):47-57. Peder E. Z. Larson, Paul T. Gurney, and Dwight G. Nishimura. View Publication.
    196. Using adiabatic inversion pulses for long-T2 suppression in ultrashort echo time (UTE) imaging. Magn Reson Med. 2007 Nov; 58(5):952-61. Larson PE, Conolly SM, Pauly JM, Nishimura DG. PMID: 17969119; PMCID: PMC2942769.
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    197. Designing long-T2 suppression pulses for ultrashort echo time imaging. Magn Reson Med. 2006 Jul; 56(1):94-103. Larson PE, Gurney PT, Nayak K, Gold GE, Pauly JM, Nishimura DG. PMID: 16724304; PMCID: PMC2942755.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    198. Montelukast dose selection in 6- to 14-year-olds: comparison of single-dose pharmacokinetics in children and adults. J Clin Pharmacol. 1999 Aug; 39(8):786-93. Knorr B, Larson P, Nguyen HH, Holland S, Reiss TF, Chervinsky P, Blake K, van Nispen CH, Noonan G, Freeman A, Haesen R, Michiels N, Rogers JD, Amin RD, Zhao J, Xu X, Seidenberg BC, Gertz BJ, Spielberg S. PMID: 10434229.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCTClinical Trials
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