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    Mark Pletcher, MD, MPH

    SchoolUCSF School of Medicine
    DepartmentEpidemiology & Biostatistics
    Address550 16th Street
    San Francisco CA 94158
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      Collapse Biography 
      Collapse Education and Training
      University of California, San Francisco Residency School of Medicine
      University of California, San FranciscoM.D.School of Medicine1998

      Collapse Overview 
      Collapse Overview
      As an epidemiologist and a general internal medicine physician, my research is designed to inform clinical decision-making and policy relevant to primary care and prevention. I focus on prevention of cardiovascular disease, and have particular interests in early life causes of atherosclerosis, primordial and primary coronary heart disease and stroke prevention, clinical decision-making regarding use of preventive medications (statins and anti-hypertensive medications) and screening for subclinical cardiovascular disease. I have special expertise in study design, decision and cost-effectiveness analysis, risk prediction, and evaluating the clinical utility of biomarkers, and I currently lead a data coordinating center for a major ongoing multicenter clinical trial, the Health eHeart Study (an online technology-enabled cardiovascular cohort study), and the Health eHeart Alliance, a PCORI-funded Patient-Powered Research Network focused on heart health. My primary appointment is in the Department of Epidemiology and Biostatistics at UCSF, and I see patients in General Internal Medicine at UCSF/Mt. Zion. I also help lead our nationally-recognized clinical research training programs, teach clinical research methods (Course Director for 2 classes), mentor students, fellows and junior faculty members, and direct the UCSF CTSI’s Informatics and Research Innovation Program.

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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Pletcher MJ, Sibley CT, Pignone M, Vittinghoff E, Greenland P. Interpretation of the coronary artery calcium score in combination with conventional cardiovascular risk factors: the Multi-Ethnic Study of Atherosclerosis (MESA). Circulation. 2013 Sep 3; 128(10):1076-84.
        View in: PubMed PMC3840900
      2. Pletcher MJ, Vittinghoff E, Kalhan R, Richman J, Safford M, Sidney S, Lin F, Kertesz S. Association between marijuana exposure and pulmonary function over 20 years. JAMA. 2012 Jan 11; 307(2):173-81.
        View in: PubMed PMC3840897
      3. Pletcher MJ. Cardiovascular risk stratification, hemoglobin a1c, and the tempo of translation: comment on "Cardiovascular risk prediction in diabetic men and women using hemoglobin A1c vs diabetes as a high-risk equivalent". Arch Intern Med. 2011 Oct 24; 171(19):1718-20.
        View in: PubMed
      4. Pletcher MJ, Pignone M. Evaluating the clinical utility of a biomarker: a review of methods for estimating health impact. Circulation. 2011 Mar 15; 123(10):1116-24.
        View in: PubMed PMC3138723
      5. Simon LJ, Bizamcer AN, Lidz CW, Stefan S, Pletcher MJ. Disparities in opioid prescribing for patients with psychiatric diagnoses presenting with pain to the emergency department. Emerg Med J. 2012 Mar; 29(3):201-4.
        View in: PubMed
      6. Reiner AP, Kahn A, Eisner BH, Pletcher MJ, Sadetsky N, Williams OD, Polak JF, Jacobs DR, Stoller ML. Kidney stones and subclinical atherosclerosis in young adults: the CARDIA study. J Urol. 2011 Mar; 185(3):920-5.
        View in: PubMed PMC3827917
      7. Nanchen D, Pletcher MJ, Cornuz J, Marques-Vidal PM, Paccaud F, Waeber G, Vollenweider P, Rodondi N. Public health impact of statin prescribing strategies based on JUPITER. Prev Med. 2011 Feb; 52(2):159-63.
        View in: PubMed
      8. Foulds J, Hooper MW, Pletcher MJ, Okuyemi KS. Do smokers of menthol cigarettes find it harder to quit smoking? Nicotine Tob Res. 2010 Dec; 12 Suppl 2:S102-9.
        View in: PubMed PMC3145377
      9. Victor RG, Ravenell JE, Freeman A, Leonard D, Bhat DG, Shafiq M, Knowles P, Storm JS, Adhikari E, Bibbins-Domingo K, Coxson PG, Pletcher MJ, Hannan P, Haley RW. Effectiveness of a barber-based intervention for improving hypertension control in black men: the BARBER-1 study: a cluster randomized trial. Arch Intern Med. 2011 Feb 28; 171(4):342-50.
        View in: PubMed PMC3365537
      10. Pletcher MJ, Hulley SB. Statin therapy in young adults: ready for prime time? J Am Coll Cardiol. 2010 Aug 17; 56(8):637-40.
        View in: PubMed
      11. Pletcher MJ, Bibbins-Domingo K, Liu K, Sidney S, Lin F, Vittinghoff E, Hulley SB. Nonoptimal lipids commonly present in young adults and coronary calcium later in life: the CARDIA (Coronary Artery Risk Development in Young Adults) study. Ann Intern Med. 2010 Aug 3; 153(3):137-46.
        View in: PubMed PMC3468943
      12. Friedlander Y, Li G, Fornage M, Williams OD, Lewis CE, Schreiner P, Pletcher MJ, Enquobahrie D, Williams M, Siscovick DS. Candidate molecular pathway genes related to appetite regulatory neural network, adipocyte homeostasis and obesity: results from the CARDIA Study. Ann Hum Genet. 2010 Sep 1; 74(5):387-98.
        View in: PubMed PMC2945878
      13. Flower K, Post A, Sussman J, Tangherlini N, Mendelson J, Pletcher MJ. Validation of triage criteria for deciding which apparently inebriated persons require emergency department care. Emerg Med J. 2011 Jul; 28(7):579-84.
        View in: PubMed
      14. Newman TB, Pletcher MJ. Coronary calcium screening. N Engl J Med. 2009 Dec 17; 361(25):2491; author reply 2491-2.
        View in: PubMed
      15. Pletcher MJ, Lazar L, Bibbins-Domingo K, Moran A, Rodondi N, Coxson P, Lightwood J, Williams L, Goldman L. Comparing impact and cost-effectiveness of primary prevention strategies for lipid-lowering. Ann Intern Med. 2009 Feb 17; 150(4):243-54.
        View in: PubMed
      16. Pletcher MJ, Bibbins-Domingo K, Lewis CE, Wei GS, Sidney S, Carr JJ, Vittinghoff E, McCulloch CE, Hulley SB. Prehypertension during young adulthood and coronary calcium later in life. Ann Intern Med. 2008 Jul 15; 149(2):91-9.
        View in: PubMed PMC2587255
      17. Pletcher MJ, Kertesz SG, Kohn MA, Gonzales R. Trends in opioid prescribing by race/ethnicity for patients seeking care in US emergency departments. JAMA. 2008 Jan 2; 299(1):70-8.
        View in: PubMed
      18. Pletcher MJ, Hulley BJ, Houston T, Kiefe CI, Benowitz N, Sidney S. Menthol cigarettes, smoking cessation, atherosclerosis, and pulmonary function: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Arch Intern Med. 2006 Sep 25; 166(17):1915-22.
        View in: PubMed
      19. Pletcher MJ, Kertesz SG, Sidney S, Kiefe CI, Hulley SB. Incidence and antecedents of nonmedical prescription opioid use in four US communities. The Coronary Artery Risk Development in Young Adults (CARDIA) prospective cohort study. Drug Alcohol Depend. 2006 Nov 8; 85(2):171-6.
        View in: PubMed
      20. Pletcher MJ, Kiefe CI, Sidney S, Carr JJ, Lewis CE, Hulley SB. Cocaine and coronary calcification in young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am Heart J. 2005 Nov; 150(5):921-6.
        View in: PubMed
      21. Pletcher MJ, Fernandez A, May TA, Westphal JR, Gamez CA, Hersh DF, Gonzales R. Unintended consequences of a quality improvement program designed to improve treatment of alcohol withdrawal in hospitalized patients. Jt Comm J Qual Patient Saf. 2005 Mar; 31(3):148-57.
        View in: PubMed
      22. Pletcher MJ, Varosy P, Kiefe CI, Lewis CE, Sidney S, Hulley SB. Alcohol consumption, binge drinking, and early coronary calcification: findings from the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am J Epidemiol. 2005 Mar 1; 161(5):423-33.
        View in: PubMed
      23. Pletcher MJ, Maselli J, Gonzales R. Uncomplicated alcohol intoxication in the emergency department: an analysis of the National Hospital Ambulatory Medical Care Survey. Am J Med. 2004 Dec 1; 117(11):863-7.
        View in: PubMed
      24. Pletcher MJ, Tice JA, Pignone M, McCulloch C, Callister TQ, Browner WS. What does my patient's coronary artery calcium score mean? Combining information from the coronary artery calcium score with information from conventional risk factors to estimate coronary heart disease risk. BMC Med. 2004 Aug 24; 2:31.
        View in: PubMed PMC515311
      25. Pletcher MJ, Tice JA, Pignone M, Browner WS. Using the coronary artery calcium score to predict coronary heart disease events: a systematic review and meta-analysis. Arch Intern Med. 2004 Jun 28; 164(12):1285-92.
        View in: PubMed
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