Yuh Nung Jan, PhD

Title(s)Professor, Physiology
SchoolSchool of Medicine
Address1550 Fourth St, #484E
San Francisco CA 94158
Phone415-502-0725
ORCID ORCID Icon0000-0003-1367-6299 Additional info
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    Other Positions
    Title(s)Howard Hughes Investigator


    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Dendrite morphogenesis, function and regeneration
    NIH R35NS097227Dec 1, 2016 - Nov 30, 2024
    Role: Principal Investigator
    Molecular mechanisms of dendrite development in mammalian CNS
    NIH R01MH084234Jan 1, 2004 - Jan 31, 2013
    Role: Principal Investigator
    Molecular Mechanisms of dendrite development in mammalia
    NIH R01NS047200Jan 1, 2004 - Dec 31, 2007
    Role: Principal Investigator
    Genetic Dissection of Dendrite Development
    NIH R37NS040929Jan 18, 2001 - Dec 31, 2016
    Role: Principal Investigator
    Genetic Dissection of Dendrite Development
    NIH R01NS040929Jan 18, 2001 - Nov 30, 2009
    Role: Principal Investigator
    LONGTERM CHANGES IN THE MAMMALIAN BRAIN
    NIH P50MH048200Sep 1, 1991 - Aug 31, 2002
    Role: Co-Investigator
    SLOW POTENTIALS IN AUTONOMIC GANGLIA
    NIH R01NS015757Dec 1, 1979 - Jun 30, 1988
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A personal perspective of the voltage-gated potassium channel studies. Nat Struct Mol Biol. 2024 Mar 28. Jan LY, Jan YN. PMID: 38548955.
      View in: PubMed   Mentions:    Fields:    
    2. Drosophila TMEM63 and mouse TMEM63A are lysosomal mechanosensory ion channels. Nat Cell Biol. 2024 Feb 22. Li K, Guo Y, Wang Y, Zhu R, Chen W, Cheng T, Zhang X, Jia Y, Liu T, Zhang W, Jan LY, Jan YN. PMID: 38388853.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Identification of a drug binding pocket in TMEM16F calcium-activated ion channel and lipid scramblase. Nat Commun. 2023 08 12; 14(1):4874. Feng S, Puchades C, Ko J, Wu H, Chen Y, Figueroa EE, Gu S, Han TW, Ho B, Cheng T, Li J, Shoichet B, Jan YN, Cheng Y, Jan LY. PMID: 37573365; PMCID: PMC10423226.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    4. A new cell in an old tactile sensory organ. Nat Cell Biol. 2023 04; 25(4):518-519. Zhu R, Jan YN. PMID: 37059881.
      View in: PubMed   Mentions:    Fields:    
    5. SLAPSHOT reveals rapid dynamics of extracellularly exposed proteome in response to calcium-activated plasma membrane phospholipid scrambling. bioRxiv. 2023 Mar 26. Tuomivaara ST, Teo CF, Jan YN, Jan LY, Wiita AP. PMID: 36993417; PMCID: PMC10055316.
      View in: PubMed   Mentions:
    6. The GARP complex prevents sterol accumulation at the trans-Golgi network during dendrite remodeling. J Cell Biol. 2023 01 02; 222(1). O'Brien CE, Younger SH, Jan LY, Jan YN. PMID: 36239632; PMCID: PMC9577387.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    7. A photo-switchable assay system for dendrite degeneration and repair in Drosophila melanogaster. Proc Natl Acad Sci U S A. 2022 08 23; 119(34):e2204577119. Liu HH, Hsu CH, Jan LY, Jan YN. PMID: 35969739; PMCID: PMC9407391.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    8. Kv1.1 preserves the neural stem cell pool and facilitates neuron maturation during adult hippocampal neurogenesis. Proc Natl Acad Sci U S A. 2022 05 31; 119(22):e2118240119. Lin King YH, Chen C, Lin King JV, Simms J, Glasscock E, Yang SB, Jan YN, Jan LY. PMID: 35613055; PMCID: PMC9295736.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    9. Steroid hormone signaling activates thermal nociception during Drosophila peripheral nervous system development. Elife. 2022 03 30; 11. Jaszczak JS, DeVault L, Jan LY, Jan YN. PMID: 35353036; PMCID: PMC8967384.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    10. Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly. Science. 2022 03 04; 375(6584):eabk2432. Li H, Janssens J, De Waegeneer M, Kolluru SS, Davie K, Gardeux V, Saelens W, David FPA, Brbic M, Spanier K, Leskovec J, McLaughlin CN, Xie Q, Jones RC, Brueckner K, Shim J, Tattikota SG, Schnorrer F, Rust K, Nystul TG, Carvalho-Santos Z, Ribeiro C, Pal S, Mahadevaraju S, Przytycka TM, Allen AM, Goodwin SF, Berry CW, Fuller MT, White-Cooper H, Matunis EL, DiNardo S, Galenza A, O'Brien LE, Dow JAT, FCA Consortium§, Jasper H, Oliver B, Perrimon N, Deplancke B, Quake SR, Luo L, Aerts S, Agarwal D, Ahmed-Braimah Y, Arbeitman M, Ariss MM, Augsburger J, Ayush K, Baker CC, Banisch T, Birker K, Bodmer R, Bolival B, Brantley SE, Brill JA, Brown NC, Buehner NA, Cai XT, Cardoso-Figueiredo R, Casares F, Chang A, Clandinin TR, Crasta S, Desplan C, Detweiler AM, Dhakan DB, Donà E, Engert S, Floc'hlay S, George N, González-Segarra AJ, Groves AK, Gumbin S, Guo Y, Harris DE, Heifetz Y, Holtz SL, Horns F, Hudry B, Hung RJ, Jan YN, Jaszczak JS, Jefferis GSXE, Karkanias J, Karr TL, Katheder NS, Kezos J, Kim AA, Kim SK, Kockel L, Konstantinides N, Kornberg TB, Krause HM, Labott AT, Laturney M, Lehmann R, Leinwand S, Li J, Li JSS, Li K, Li K, Li L, Li T, Litovchenko M, Liu HH, Liu Y, Lu TC, Manning J, Mase A, Matera-Vatnick M, Matias NR, McDonough-Goldstein CE, McGeever A, McLachlan AD, Moreno-Roman P, Neff N, Neville M, Ngo S, Nielsen T, O'Brien CE, Osumi-Sutherland D, Özel MN, Papatheodorou I, Petkovic M, Pilgrim C, Pisco AO, Reisenman C, Sanders EN, Dos Santos G, Scott K, Sherlekar A, Shiu P, Sims D, Sit RV, Slaidina M, Smith HE, Sterne G, Su YH, Sutton D, Tamayo M, Tan M, Tastekin I, Treiber C, Vacek D, Vogler G, Waddell S, Wang W, Wilson RI, Wolfner MF, Wong YE, Xie A, Xu J, Yamamoto S, Yan J, Yao Z, Yoda K, Zhu R, Zinzen RP. PMID: 35239393; PMCID: PMC8944923.
      View in: PubMed   Mentions: 175     Fields:    Translation:AnimalsCells
    11. Identification of a conserved drug binding pocket in TMEM16 proteins. Res Sq. 2022 Feb 10. Cheng Y, Feng S, Puchades C, Ko J, Figueroa E, Chen Y, Wu H, Gu S, Han T, Li J, Ho B, Shoichet B, Jan YN, Jan L. PMID: 35169791; PMCID: PMC8845511.
      View in: PubMed   Mentions:
    12. Underrepresentation of Asian awardees of United States biomedical research prizes. Cell. 2022 02 03; 185(3):407-410. Jan YN. PMID: 35120660.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    13. Kv1.1 channels regulate early postnatal neurogenesis in mouse hippocampus via the TrkB signaling pathway. Elife. 2021 05 21; 10. Chou SM, Li KX, Huang MY, Chen C, Lin King YH, Li GG, Zhou W, Teo CF, Jan YN, Jan LY, Yang SB. PMID: 34018923; PMCID: PMC8208815.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    14. TMEM16C is involved in thermoregulation and protects rodent pups from febrile seizures. Proc Natl Acad Sci U S A. 2021 05 18; 118(20). Wang TA, Chen C, Huang F, Feng S, Tien J, Braz JM, Basbaum AI, Jan YN, Jan LY. PMID: 33972431; PMCID: PMC8157992.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    15. Interorganelle communication, aging, and neurodegeneration. Genes Dev. 2021 04 01; 35(7-8):449-469. Petkovic M, O'Brien CE, Jan YN. PMID: 33861720; PMCID: PMC8015714.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    16. Visceral Mechano-sensing Neurons Control Drosophila Feeding by Using Piezo as a Sensor. Neuron. 2020 11 25; 108(4):640-650.e4. Wang P, Jia Y, Liu T, Jan YN, Zhang W. PMID: 32910893; PMCID: PMC8386590.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    17. TMEM16K is an interorganelle regulator of endosomal sorting. Nat Commun. 2020 07 03; 11(1):3298. Petkovic M, Oses-Prieto J, Burlingame A, Jan LY, Jan YN. PMID: 32620747; PMCID: PMC7335067.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    18. Chloride channels regulate differentiation and barrier functions of the mammalian airway. Elife. 2020 04 14; 9. He M, Wu B, Ye W, Le DD, Sinclair AW, Padovano V, Chen Y, Li KX, Sit R, Tan M, Caplan MJ, Neff N, Jan YN, Darmanis S, Jan LY. PMID: 32286221; PMCID: PMC7182432.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    19. Mechanisms of neurite repair. Curr Opin Neurobiol. 2020 08; 63:53-58. Liu HH, Jan YN. PMID: 32278210; PMCID: PMC7534396.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    20. Mechanosensitive Ion Channels: Structural Features Relevant to Mechanotransduction Mechanisms. Annu Rev Neurosci. 2020 07 08; 43:207-229. Jin P, Jan LY, Jan YN. PMID: 32084327.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    21. The microtubule regulator ringer functions downstream from the RNA repair/splicing pathway to promote axon regeneration. Genes Dev. 2020 02 01; 34(3-4):194-208. Vargas EJM, Matamoros AJ, Qiu J, Jan CH, Wang Q, Gorczyca D, Han TW, Weissman JS, Jan YN, Banerjee S, Song Y. PMID: 31919191; PMCID: PMC7000917.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    22. Paralytic, the Drosophila voltage-gated sodium channel, regulates proliferation of neural progenitors. Genes Dev. 2019 12 01; 33(23-24):1739-1750. Piggott BJ, Peters CJ, He Y, Huang X, Younger S, Jan LY, Jan YN. PMID: 31753914; PMCID: PMC6942049.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    23. TMEM16B regulates anxiety-related behavior and GABAergic neuronal signaling in the central lateral amygdala. Elife. 2019 09 04; 8. Li KX, He M, Ye W, Simms J, Gill M, Xiang X, Jan YN, Jan LY. PMID: 31482844; PMCID: PMC6746550.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    24. Cryo-EM Studies of TMEM16F Calcium-Activated Ion Channel Suggest Features Important for Lipid Scrambling. Cell Rep. 2019 Jul 30; 28(5):1385. Feng S, Dang S, Han TW, Ye W, Jin P, Cheng T, Li J, Jan YN, Jan LY, Cheng Y. PMID: 31365878; PMCID: PMC6690723.
      View in: PubMed   Mentions: 9     Fields:    
    25. TMEM16B Calcium-Activated Chloride Channels Regulate Action Potential Firing in Lateral Septum and Aggression in Male Mice. J Neurosci. 2019 09 04; 39(36):7102-7117. Wang L, Simms J, Peters CJ, Tynan-La Fontaine M, Li K, Gill TM, Jan YN, Jan LY. PMID: 31320449; PMCID: PMC6733546.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    26. Dynamic change of electrostatic field in TMEM16F permeation pathway shifts its ion selectivity. Elife. 2019 07 18; 8. Ye W, Han TW, He M, Jan YN, Jan LY. PMID: 31318330; PMCID: PMC6690719.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    27. Thermoregulation via Temperature-Dependent PGD2 Production in Mouse Preoptic Area. Neuron. 2019 Jul 17; 103(2):349. Wang TA, Teo CF, Åkerblom M, Chen C, Tynan-La Fontaine M, Greiner VJ, Diaz A, McManus MT, Jan YN, Jan LY. PMID: 31319050.
      View in: PubMed   Mentions: 4     Fields:    
    28. Cryo-EM Studies of TMEM16F Calcium-Activated Ion Channel Suggest Features Important for Lipid Scrambling. Cell Rep. 2019 07 09; 28(2):567-579.e4. Feng S, Dang S, Han TW, Ye W, Jin P, Cheng T, Li J, Jan YN, Jan LY, Cheng Y. PMID: 31291589; PMCID: PMC6684876.
      View in: PubMed   Mentions: 41     Fields:    
    29. TMEM16A controls EGF-induced calcium signaling implicated in pancreatic cancer prognosis. Proc Natl Acad Sci U S A. 2019 06 25; 116(26):13026-13035. Crottès D, Lin YT, Peters CJ, Gilchrist JM, Wiita AP, Jan YN, Jan LY. PMID: 31182586; PMCID: PMC6600921.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    30. Thermoregulation via Temperature-Dependent PGD2 Production in Mouse Preoptic Area. Neuron. 2019 07 17; 103(2):309-322.e7. Wang TA, Teo CF, Åkerblom M, Chen C, Tynan-La Fontaine M, Greiner VJ, Diaz A, McManus MT, Jan YN, Jan LY. PMID: 31151773; PMCID: PMC6639135.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    31. JNK signaling coordinates with ecdysone signaling to promote pruning of Drosophila sensory neuron dendrites. Development. 2019 04 17; 146(8). Zhu S, Chen R, Soba P, Jan YN. PMID: 30936183; PMCID: PMC6503988.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    32. The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration. Neuron. 2019 04 17; 102(2):373-389.e6. Song Y, Li D, Farrelly O, Miles L, Li F, Kim SE, Lo TY, Wang F, Li T, Thompson-Peer KL, Gong J, Murthy SE, Coste B, Yakubovich N, Patapoutian A, Xiang Y, Rompolas P, Jan LY, Jan YN. PMID: 30819546; PMCID: PMC6487666.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    33. Glial ensheathment of the somatodendritic compartment regulates sensory neuron structure and activity. Proc Natl Acad Sci U S A. 2019 03 12; 116(11):5126-5134. Yadav S, Younger SH, Zhang L, Thompson-Peer KL, Li T, Jan LY, Jan YN. PMID: 30804200; PMCID: PMC6421456.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    34. Chemically induced vesiculation as a platform for studying TMEM16F activity. Proc Natl Acad Sci U S A. 2019 01 22; 116(4):1309-1318. Han TW, Ye W, Bethel NP, Zubia M, Kim A, Li KH, Burlingame AL, Grabe M, Jan YN, Jan LY. PMID: 30622179; PMCID: PMC6347726.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    35. Coiled-coil structure-dependent interactions between polyQ proteins and Foxo lead to dendrite pathology and behavioral defects. Proc Natl Acad Sci U S A. 2018 11 06; 115(45):E10748-E10757. Kwon MJ, Han MH, Bagley JA, Hyeon DY, Ko BS, Lee YM, Cha IJ, Kim SY, Kim DY, Kim HM, Hwang D, Lee SB, Jan YN. PMID: 30348793; PMCID: PMC6233066.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    36. Influences: Cold Spring Harbor summer courses and Drosophila melanogaster neurogenetics. J Gen Physiol. 2018 06 04; 150(6):773-775. Jan LY, Jan YN. PMID: 29769227; PMCID: PMC5987881.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    37. Dendrite regeneration of adult Drosophila sensory neurons diminishes with aging and is inhibited by epidermal-derived matrix metalloproteinase 2. Genes Dev. 2018 03 01; 32(5-6):402-414. DeVault L, Li T, Izabel S, Thompson-Peer KL, Jan LY, Jan YN. PMID: 29563183; PMCID: PMC5900713.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    38. Force-activated ion channels in close-up. Nature. 2018 02 22; 554(7693):469-470. Jan YN, Jan LY. PMID: 29469134.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    39. The Sixth Transmembrane Segment Is a Major Gating Component of the TMEM16A Calcium-Activated Chloride Channel. Neuron. 2018 03 07; 97(5):1063-1077.e4. Peters CJ, Gilchrist JM, Tien J, Bethel NP, Qi L, Chen T, Wang L, Jan YN, Grabe M, Jan LY. PMID: 29478917; PMCID: PMC5860880.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    40. Force-activated ion channels in close-up. Nature. 2018 Feb; 554(7693):469-470. Jan YN, Jan LY. PMID: 32094930.
      View in: PubMed   Mentions:    Fields:    
    41. Phosphatidylinositol-(4, 5)-bisphosphate regulates calcium gating of small-conductance cation channel TMEM16F. Proc Natl Acad Sci U S A. 2018 02 13; 115(7):E1667-E1674. Ye W, Han TW, Nassar LM, Zubia M, Jan YN, Jan LY. PMID: 29382763; PMCID: PMC5816197.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    42. Cryo-EM structures of the TMEM16A calcium-activated chloride channel. Nature. 2017 12 21; 552(7685):426-429. Dang S, Feng S, Tien J, Peters CJ, Bulkley D, Lolicato M, Zhao J, Zuberbühler K, Ye W, Qi L, Chen T, Craik CS, Jan YN, Minor DL, Cheng Y, Jan LY. PMID: 29236684; PMCID: PMC5750132.
      View in: PubMed   Mentions: 163     Fields:    Translation:HumansAnimalsCells
    43. Cytoplasmic Cl- couples membrane remodeling to epithelial morphogenesis. Proc Natl Acad Sci U S A. 2017 12 26; 114(52):E11161-E11169. He M, Ye W, Wang WJ, Sison ES, Jan YN, Jan LY. PMID: 29229864; PMCID: PMC5748203.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    44. Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder. Cell Rep. 2017 Dec 05; 21(10):2678-2687. Deshpande A, Yadav S, Dao DQ, Wu ZY, Hokanson KC, Cahill MK, Wiita AP, Jan YN, Ullian EM, Weiss LA. PMID: 29212016; PMCID: PMC5730067.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    45. Phospholipid Homeostasis Regulates Dendrite Morphogenesis in Drosophila Sensory Neurons. Cell Rep. 2017 Oct 24; 21(4):859-866. Meltzer S, Bagley JA, Perez GL, O'Brien CE, DeVault L, Guo Y, Jan LY, Jan YN. PMID: 29069593; PMCID: PMC5687885.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    46. Composition and Control of a Deg/ENaC Channel during Presynaptic Homeostatic Plasticity. Cell Rep. 2017 Aug 22; 20(8):1855-1866. Orr BO, Gorczyca D, Younger MA, Jan LY, Jan YN, Davis GW. PMID: 28834749; PMCID: PMC5599149.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    47. Electron cryo-microscopy structure of the mechanotransduction channel NOMPC. Nature. 2017 07 06; 547(7661):118-122. Jin P, Bulkley D, Guo Y, Zhang W, Guo Z, Huynh W, Wu S, Meltzer S, Cheng T, Jan LY, Jan YN, Cheng Y. PMID: 28658211; PMCID: PMC5669069.
      View in: PubMed   Mentions: 109     Fields:    Translation:AnimalsCells
    48. Age-dependent diastolic heart failure in an in vivo Drosophila model. Elife. 2017 03 22; 6. Klassen MP, Peters CJ, Zhou S, Williams HH, Jan LY, Jan YN. PMID: 28328397; PMCID: PMC5362267.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    49. TAOK2 Kinase Mediates PSD95 Stability and Dendritic Spine Maturation through Septin7 Phosphorylation. Neuron. 2017 Jan 18; 93(2):379-393. Yadav S, Oses-Prieto JA, Peters CJ, Zhou J, Pleasure SJ, Burlingame AL, Jan LY, Jan YN. PMID: 28065648; PMCID: PMC5267388.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    50. A Defensive Kicking Behavior in Response to Mechanical Stimuli Mediated by Drosophila Wing Margin Bristles. J Neurosci. 2016 11 02; 36(44):11275-11282. Li J, Zhang W, Guo Z, Wu S, Jan LY, Jan YN. PMID: 27807168; PMCID: PMC5148243.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    51. N-linked glycosylation of Kv1.2 voltage-gated potassium channel facilitates cell surface expression and enhances the stability of internalized channels. J Physiol. 2016 11 15; 594(22):6701-6713. Thayer DA, Yang SB, Jan YN, Jan LY. PMID: 27377235; PMCID: PMC5108895.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    52. In vivo dendrite regeneration after injury is different from dendrite development. Genes Dev. 2016 08 01; 30(15):1776-89. Thompson-Peer KL, DeVault L, Li T, Jan LY, Jan YN. PMID: 27542831; PMCID: PMC5002981.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    53. Transmembrane channel-like (tmc) gene regulates Drosophila larval locomotion. Proc Natl Acad Sci U S A. 2016 06 28; 113(26):7243-8. Guo Y, Wang Y, Zhang W, Meltzer S, Zanini D, Yu Y, Li J, Cheng T, Guo Z, Wang Q, Jacobs JS, Sharma Y, Eberl DF, Göpfert MC, Jan LY, Jan YN, Wang Z. PMID: 27298354; PMCID: PMC4932980.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    54. Phosphorylation of β-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis. Neuron. 2016 05 04; 90(3):551-63. Ori-McKenney KM, McKenney RJ, Huang HH, Li T, Meltzer S, Jan LY, Vale RD, Wiita AP, Jan YN. PMID: 27112495; PMCID: PMC4860041.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    55. Epidermis-Derived Semaphorin Promotes Dendrite Self-Avoidance by Regulating Dendrite-Substrate Adhesion in Drosophila Sensory Neurons. Neuron. 2016 Feb 17; 89(4):741-55. Meltzer S, Yadav S, Lee J, Soba P, Younger SH, Jin P, Zhang W, Parrish J, Jan LY, Jan YN. PMID: 26853303; PMCID: PMC4760923.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    56. Rational design of a monomeric and photostable far-red fluorescent protein for fluorescence imaging in vivo. Protein Sci. 2016 Feb; 25(2):308-15. Yu D, Dong Z, Gustafson WC, Ruiz-González R, Signor L, Marzocca F, Borel F, Klassen MP, Makhijani K, Royant A, Jan YN, Weiss WA, Guo S, Shu X. PMID: 26549191; PMCID: PMC4815332.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    57. Spindle-F Is the Central Mediator of Ik2 Kinase-Dependent Dendrite Pruning in Drosophila Sensory Neurons. PLoS Genet. 2015 Nov; 11(11):e1005642. Lin T, Pan PY, Lai YT, Chiang KW, Hsieh HL, Wu YP, Ke JM, Lee MC, Liao SS, Shih HT, Tang CY, Yang SB, Cheng HC, Wu JT, Jan YN, Lee HH. PMID: 26540204; PMCID: PMC4634852.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    58. Ankyrin Repeats Convey Force to Gate the NOMPC Mechanotransduction Channel. Cell. 2015 Sep 10; 162(6):1391-403. Zhang W, Cheng LE, Kittelmann M, Li J, Petkovic M, Cheng T, Jin P, Guo Z, Göpfert MC, Jan LY, Jan YN. PMID: 26359990; PMCID: PMC4568062.
      View in: PubMed   Mentions: 95     Fields:    Translation:AnimalsCells
    59. EAG2 potassium channel with evolutionarily conserved function as a brain tumor target. Nat Neurosci. 2015 Sep; 18(9):1236-46. Huang X, He Y, Dubuc AM, Hashizume R, Zhang W, Reimand J, Yang H, Wang TA, Stehbens SJ, Younger S, Barshow S, Zhu S, Cooper MK, Peacock J, Ramaswamy V, Garzia L, Wu X, Remke M, Forester CM, Kim CC, Weiss WA, James CD, Shuman MA, Bader GD, Mueller S, Taylor MD, Jan YN, Jan LY. PMID: 26258683; PMCID: PMC4639927.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
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    396. Identification of a component of Drosophila polar granules. Development. 1988 Aug; 103(4):625-40. Hay B, Ackerman L, Barbel S, Jan LY, Jan YN. PMID: 3150351.
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    397. The maternal sex determination gene daughterless has zygotic activity necessary for the formation of peripheral neurons in Drosophila. Genes Dev. 1988 Jul; 2(7):843-52. Caudy M, Grell EH, Dambly-Chaudière C, Ghysen A, Jan LY, Jan YN. PMID: 3209070.
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    398. Primary structure and expression of a product from cut, a locus involved in specifying sensory organ identity in Drosophila. Nature. 1988 Jun 16; 333(6174):629-35. Blochlinger K, Bodmer R, Jack J, Jan LY, Jan YN. PMID: 2897632.
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    399. Identification and characterization of a neuron-specific nuclear antigen in Drosophila. Science. 1988 May 13; 240(4854):913-6. Bier E, Ackerman L, Barbel S, Jan L, Jan YN. PMID: 3129785.
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    400. Cloning of a probable potassium channel gene from mouse brain. Nature. 1988 Apr 28; 332(6167):837-9. Tempel BL, Jan YN, Jan LY. PMID: 2451788.
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    401. Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila. Nature. 1988 Jan 14; 331(6152):137-42. Schwarz TL, Tempel BL, Papazian DM, Jan YN, Jan LY. PMID: 2448635.
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    402. Expression of functional potassium channels from Shaker cDNA in Xenopus oocytes. Nature. 1988 Jan 14; 331(6152):143-5. Timpe LC, Schwarz TL, Tempel BL, Papazian DM, Jan YN, Jan LY. PMID: 2448636.
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    403. Neurotoxins from Plectreurys spider venom are potent presynaptic blockers in Drosophila. J Neurosci. 1987 Dec; 7(12):4195-200. Branton WD, Kolton L, Jan YN, Jan LY. PMID: 2826721; PMCID: PMC6569098.
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    404. Transformation of sensory organs by mutations of the cut locus of D. melanogaster. Cell. 1987 Oct 23; 51(2):293-307. Bodmer R, Barbel S, Sheperd S, Jack JW, Jan LY, Jan YN. PMID: 3117374.
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    405. Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila. Science. 1987 Aug 14; 237(4816):770-5. Tempel BL, Papazian DM, Schwarz TL, Jan YN, Jan LY. PMID: 2441471.
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    406. Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from Drosophila. Science. 1987 Aug 14; 237(4816):749-53. Papazian DM, Schwarz TL, Tempel BL, Jan YN, Jan LY. PMID: 2441470.
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    407. Identification and purification of an irreversible presynaptic neurotoxin from the venom of the spider Hololena curta. Proc Natl Acad Sci U S A. 1987 May; 84(10):3506-10. Bowers CW, Phillips HS, Lee P, Jan YN, Jan LY. PMID: 3033650; PMCID: PMC304900.
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    408. Morphological differentiation of the embryonic peripheral neurons in Drosophila. Rouxs Arch Dev Biol. 1987 Feb; 196(2):69-77. Bodmer R, Jan YN. PMID: 28305460.
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    409. Muscle connections between imaginal discs in Drosophila. Dev Biol. 1986 Feb; 113(2):288-94. Dambly-Chaudière C, Ghysen A, Jan YN, Jan LY. PMID: 3081389.
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    410. The LHRH family of peptide messengers in the frog nervous system. Prog Brain Res. 1986; 68:205-15. Branton WD, Phillips HS, Jan YN. PMID: 3550890.
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    411. Formation of neuronal pathways in the imaginal discs of Drosophila melanogaster. J Neurosci. 1985 Sep; 5(9):2453-64. Jan YN, Ghysen A, Christoph I, Barbel S, Jan LY. PMID: 3928832; PMCID: PMC6565306.
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    412. Selective phosphorylation of cytosol proteins associated with transformation and restoration of normal phenotype in AKR mouse embryo fibroblasts. Cancer Res. 1985 May; 45(5):2170-6. Chakrabarty S, Jan Y, Son J, Miller CA, Brattain MG. PMID: 3872713.
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    413. Segmental determination in Drosophila central nervous system. Cell. 1985 Apr; 40(4):943-8. Ghysen A, Jan LY, Jan YN. PMID: 3886161.
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    414. Mutating a gene for a potassium channel by hybrid dysgenesis: an approach to the cloning of the Shaker locus in Drosophila. Cold Spring Harb Symp Quant Biol. 1983; 48 Pt 1:233-45. Jan LY, Barbel S, Timpe L, Laffer C, Salkoff L, O'Farrell P, Jan YN. PMID: 6327158.
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    415. Peptides in neuronal function: studies using frog autonomic ganglia. Cold Spring Harb Symp Quant Biol. 1983; 48 Pt 1:363-74. Jan YN, Bowers CW, Branton D, Evans L, Jan LY. PMID: 6327165.
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    416. Some features of peptidergic transmission. Prog Brain Res. 1983; 58:49-59. Jan YN, Jan LY. PMID: 6138814.
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    417. Peptidergic transmission in sympathetic ganglia of the frog. J Physiol. 1982 Jun; 327:219-46. Jan LY, Jan YN. PMID: 6181250; PMCID: PMC1225105.
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    418. Antibodies to horseradish peroxidase as specific neuronal markers in Drosophila and in grasshopper embryos. Proc Natl Acad Sci U S A. 1982 Apr; 79(8):2700-4. Jan LY, Jan YN. PMID: 6806816; PMCID: PMC346269.
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    419. Segmental differences in the protein content of Drosophila imaginal discs. EMBO J. 1982; 1(11):1373-9. Ghysen A, Dambly-Chaudière C, Jan LY, Jan YN. PMID: 16453437; PMCID: PMC553219.
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    420. Role of an LHRH-like peptide as a neurotransmitter is sympathetic ganglia of the frog. Fed Proc. 1981 Sep; 40(11):2560-4. Jan LY, Jan YN. PMID: 6115771.
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    421. Peptidergic transmitters in synaptic boutons of sympathetic ganglia. Nature. 1980 Nov 27; 288(5789):380-2. Jan LY, Jan YN, Brownfield MS. PMID: 6107864.
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    422. Further evidence for peptidergic transmission in sympathetic ganglia. Proc Natl Acad Sci U S A. 1980 Aug; 77(8):5008-12. Jan YN, Jan LY, Kuffler SW. PMID: 6254052; PMCID: PMC349979.
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    423. Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter release. J Cell Biol. 1979 May; 81(2):275-300. Heuser JE, Reese TS, Dennis MJ, Jan Y, Jan L, Evans L. PMID: 38256; PMCID: PMC2110310.
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    424. A Drosophila mutant with a temperature-sensitive block in nerve conduction. Proc Natl Acad Sci U S A. 1978 Aug; 75(8):4047-51. Wu CF, Ganetzky B, Jan LY, Jan YN, Benzer S. PMID: 211514; PMCID: PMC392928.
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    425. L-glutamate as an excitatory transmitter at the Drosophila larval neuromuscular junction. J Physiol. 1976 Oct; 262(1):215-36. Jan LY, Jan YN. PMID: 186587; PMCID: PMC1307638.
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    426. dunce, a mutant of Drosophila deficient in learning. Proc Natl Acad Sci U S A. 1976 May; 73(5):1684-8. Dudai Y, Jan YN, Byers D, Quinn WG, Benzer S. PMID: 818641; PMCID: PMC430364.
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    427. Avoidance response, house response, and wind responses of the sporangiophore of Phycomyces. J Gen Physiol. 1975 Jul; 66(1):67-95. Cohen RJ, Jan YN, Matricon J, Delbrück M. PMID: 1159403; PMCID: PMC2226190.
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    428. [Bacterial endocarditis in children associated with congenital cardiopathies: clinical aspects and outcome. Apropos of 22 cases]. Arch Fr Pediatr. 1974 Dec; 31(10):955-71. Jan Y, Loth P. PMID: 4463929.
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