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    Daniel Vigneron, PhD

    SchoolUCSF School of Medicine
    Address1700 4th Street
    San Francisco CA 94158
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      Collapse Biography 
      Collapse Education and Training
      University of California, San FranciscoPh.D. Graduate Division (Pharmaceutical Chemistry)1990
      Collapse Awards and Honors
      Academy of Radiology Research 2013Distinguished Investigator Award
      International Society of Magnetic Resonance in Medicine2011Distinguished Service Award as Reviewer for Journal of Magnetic Resonance Imaging
      International Society of Magnetic Resonance in Medicine2009Awarded Fellow of ISMRM
      American Institute for Medical and Biological Engineering2007Elected to the College of Fellow
      American Society of Neuroradiology2007Outstanding Presentation Award
      American Society of Neuroradiology2001Outstanding Presentation Award in Pediatric Neuroradiology - The Derek Harwood-Nash Award
      CaP Cure Foundation 2000Prostate Cancer Research Award
      CaP Cure Foundation 1999Prostate Cancer Research Award
      CaP Cure Foundation 1998Prostate Cancer Research Award
      National Cancer Institute, National Institutes of Health1990National Research Service Award
      Wesleyan University1983Hawk Prize for Most Effective Work in Biochemistry

      Collapse Overview 
      Collapse Overview
      Daniel B. Vigneron, PhD, is a Professor in the Department of Radiology and Biomedical Imaging and a Professor in the Department of Bioengineering and Therapeutic Sciences at the University of California, San Francisco. He is also Director of the Advanced Imaging Technologies Resource Group, Director of the Hyperpolarized MRI Technology Resource Center, and Associate Director of the Surbeck Laboratory for Advanced Imaging at UCSF. Dr. Vigneron’s professional activities focus on the advancement of biomedical MRI research. Dr. Vigneron obtained his BA in Chemistry from Wesleyan University in Middletown, Connecticut in 1983, and he received his PhD in Pharmaceutical Chemistry from UCSF in 1988 for his graduate work on applying new MRI techniques for characterizing disease and therapy response. In 1990, he completed a postdoctoral fellowship from the Fox Chase Cancer Center in Philadelphia and in 1991 he completed a postdoctoral scholarship from UCSF.

      Dr. Vigneron’s research is focused on the development of metabolic magnetic resonance imaging techniques for research and clinical assessments of human diseases. His initial focus was on developing 3D MR spectroscopic imaging for the non-invasive assessment of brain tumor metabolism. Another major research interest of Dr. Vigneron’s is the characterization of prostate cancer using novel MR metabolic imaging techniques. Developing specialized acquisitions techniques for prostate cancer MRSI has been a major project for Dr. Vigneron and his group.

      Dr. Vigneron leads the technical development aspects of hyperpolarized carbon-13 MR program at UCSF and is the Principal Investigator of three projects focused on new metabolic MRI techniques. He has published over 200 articles, over 10 book chapters and over 450 abstracts related to his research.

      Radiology and Biomedical Imaging

      MRI, hyperpolarized MRI techniques, brain tumor, prostate cancer

      Professional Interests:
      Magnetic resonance imaging, magnetic resonance spectroscopy, molecular imaging, metabolic imaging, diffusion tensor imaging, oncologic imaging, prostate cancer imaging, pediatric imaging.

      Education and Training:
      • Bachelor of Arts: Wesleyan University, Middletown, Connecticut - Chemistry, Pre-Med Studies
      • Doctor of Philosophy: University of California, San Francisco - Pharmaceutical Chemistry
      • Research Fellow: Fox Chase Cancer Center, Philadelphia
      • Visiting Postdoctoral Scholar: University of California, San Francisco - Department of Radiology

      Collapse Interests
      Magnetic resonance imaging, magnetic resonance spectroscopy, molecular imaging, metabolic imaging, diffusion tensor imaging, oncologic imaging, prostate cancer imaging, pediatric imaging.

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      Collapse In The News
      Collapse NIH Awarded Grants
      Collapse Global Health

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. von Morze C, Bok RA, Reed GD, Ardenkjaer-Larsen JH, Kurhanewicz J, Vigneron DB. Simultaneous multiagent hyperpolarized (13) C perfusion imaging. Magn Reson Med. 2014 Dec; 72(6):1599-609.
        View in: PubMed PMC4077988
      2. Shin PJ, Larson PE, Ohliger MA, Elad M, Pauly JM, Vigneron DB, Lustig M. Calibrationless parallel imaging reconstruction based on structured low-rank matrix completion. Magn Reson Med. 2014 Oct; 72(4):959-70.
        View in: PubMed PMC4025999
      3. Reed GD, von Morze C, Bok R, Koelsch BL, Van Criekinge M, Smith KJ. High resolution (13)C MRI with hyperpolarized urea: in vivo T(2) mapping and (15)N labeling effects. IEEE Trans Med Imaging. 2014 Feb; 33(2):362-71.
        View in: PubMed PMC4011557
      4. Keshari KR, Sriram R, Van Criekinge M, Wilson DM, Wang ZJ, Vigneron DB, Peehl DM, Kurhanewicz J. Metabolic reprogramming and validation of hyperpolarized 13C lactate as a prostate cancer biomarker using a human prostate tissue slice culture bioreactor. Prostate. 2013 Aug; 73(11):1171-81.
        View in: PubMed PMC3976546
      5. Swisher CL, Larson PE, Kruttwig K, Kerr AB, Hu S, Bok RA, Goga A, Pauly JM, Nelson SJ, Kurhanewicz J, Vigneron DB. Quantitative measurement of cancer metabolism using stimulated echo hyperpolarized carbon-13 MRS. Magn Reson Med. 2014 Jan; 71(1):1-11.
        View in: PubMed PMC3659200
      6. Ohliger MA, Larson PE, Bok RA, Shin P, Hu S, Tropp J, Robb F, Carvajal L, Nelson SJ, Kurhanewicz J, Vigneron DB. Combined parallel and partial fourier MR reconstruction for accelerated 8-channel hyperpolarized carbon-13 in vivo magnetic resonance Spectroscopic imaging (MRSI). J Magn Reson Imaging. 2013 Sep; 38(3):701-13.
        View in: PubMed PMC3759833
      7. Larson PE, Hurd RE, Kerr AB, Pauly JM, Bok RA, Kurhanewicz J, Vigneron DB. Perfusion and diffusion sensitive 13C stimulated-echo MRSI for metabolic imaging of cancer. Magn Reson Imaging. 2013 Jun; 31(5):635-42.
        View in: PubMed PMC3626756
      8. Park I, Hu S, Bok R, Ozawa T, Ito M, Mukherjee J, Phillips JJ, James CD, Pieper RO, Ronen SM, Vigneron DB, Nelson SJ. Evaluation of heterogeneous metabolic profile in an orthotopic human glioblastoma xenograft model using compressed sensing hyperpolarized 3D 13C magnetic resonance spectroscopic imaging. Magn Reson Med. 2013 Jul; 70(1):33-9.
        View in: PubMed PMC3630274
      9. Pang Y, Wu B, Wang C, Vigneron DB, Zhang X. Numerical Analysis of Human Sample Effect on RF Penetration and Liver MR Imaging at Ultrahigh Field. Concepts Magn Reson Part B Magn Reson Eng. 2011 Oct; 39B(4):206-216.
        View in: PubMed
      10. Pang Y, Xie Z, Li Y, Xu D, Vigneron D, Zhang X. Resonant Mode Reduction in Radiofrequency Volume Coils for Ultrahigh Field Magnetic Resonance Imaging. Materials (Basel). 2011 Jul 28; 4(8):1333-1344.
        View in: PubMed
      11. Reed G, Cunha JA, Noworolski S, Kurhanewicz J, Vigneron D, Hsu IC, Pouliot J. Interactive, multi-modality image registrations for combined MRI/MRSI-planned HDR prostate brachytherapy. J Contemp Brachytherapy. 2011 Mar 31; 3(1):26-31.
        View in: PubMed
      12. Li Y, Pang Y, Vigneron D, Glenn O, Xu D, Zhang X. Investigation of multichannel phased array performance for fetal MR imaging on 1.5T clinical MR system. Quant Imaging Med Surg. 2011 Jan 1; 1(1):24-30.
        View in: PubMed
      13. Nelson SJ, Vigneron D, Kurhanewicz J, Chen A, Bok R, Hurd R. DNP-Hyperpolarized C Magnetic Resonance Metabolic Imaging for Cancer Applications. Appl Magn Reson. 2008; 34(3-4):533-544.
        View in: PubMed
      14. von Morze C, Tropp J, Banerjee S, Xu D, Karpodinis K, Carvajal L, Hess CP, Mukherjee P, Majumdar S, Vigneron DB. Concepts in Magnetic Resonance, Part B: (Magnetic Resonance Engineering). An Eight-Channel, Non-Overlapping Phased Array Coil With Capacitive Decoupling For Parallel MRI At 3T. 2007; 31B:37-43.
      15. Vigneron DB, Swanson MG, Kurhanewicz J. SMRT Educational Seminars. Advances in Prostate MR Imaging: MR Spectroscopic Imaging at 1.5T and 3.0T. 2004; 7:11-21.
      16. Dumoulin CL, Rohling KW, Piel JE, Rossi CJ, Giaquinto RO, Watkins RD, Vigneron DB, Barkovich AJ, Newton N. . Concepts in Magnetic Resonance (Magn Reson Engineering). An MRI compatible neonate incubator. 2002; 15:117-128.
      17. James TL, Chew WM, Gonzalez-Mendez R, Moseley M, Murphy-Boesch J, Pogliano L, Vigneron DB. . Applied Radiology. Magnetic resonance spectroscopy principles and potential applications. 1987; 16:40-52.
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