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Jeffrey Gelfand, MD

Address675 Nelson Rising Lane
San Francisco CA 94158
Phone415-353-8365
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    Collapse Biography 
    Collapse education and training
    University of California, San FranciscoMAS2013Advanced Training in Clinical Research
    Harvard Medical SchoolM.D.2006
    Princeton UniversityA.B.2001History
    Collapse Awards and Honors
    AAN2016Elected as a Fellow of the American Academy of Neurology (FAAN)
    Marin Magazine2016[415] Top Doctor
    UCSF School of Medicine2015Excellence in Teaching Award -- Haile T. Debas Academy of Medical Educators
    UCSF Department of Neurology2014Robert B. Layzer Award for Resident Teaching
    SF Neurological Society2011Newman Award
    SF Neurological Society2009Newman Award
    Princeton University2001Summa Cum Laude and Phi Beta Kappa
    Princeton University2001Walter Phelps Hall Prize for the Best Thesis in European History

    Collapse Overview 
    Collapse overview
    Dr. Gelfand is an Assistant Professor of Clinical Neurology at UCSF. He specializes in caring for patients with a wide range of neuroinflammatory disorders. Dr. Gelfand conducts clinical research focused on advancing new treatments for neuroimmunological diseases and restoring neurological function. Dr. Gelfand is also an award-winning medical educator.

    Dr. Gelfand received an A.B. in history from Princeton University, graduating summa cum laude and Phi Beta Kappa. He received his M.D. from Harvard Medical School. He completed an internship in internal medicine, residency in neurology and subspecialty fellowship training in MS/neuroimmunology, all at UCSF. Dr. Gelfand went on to earn a Masters in Advanced Study in clinical research at UCSF. He is board-certified in neurology.

    Dr. Gelfand directs the UCSF MS Center Clinical Fellowship Training Program (training specialists in MS/neuroimmunology after completion of neurology residency). In 2014 Dr. Gelfand received the Robert B. Layzer teaching award, which is voted on annually by UCSF Neurology Department residents, and in 2015 he received an Excellence in Teaching Award from the UCSF Haile T. Debas Academy of Medical Educators.

    Dr. Gelfand is a Fellow of the American Academy of Neurology (FAAN) and serves as a member of the AAN Clinical Research Subcommittee. In 2016 Dr. Gelfand chaired the American Neurological Association (ANA) Autoimmune Neurology Special Interest Group.


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    Collapse Bibliographic 
    Collapse Selected Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Gelfand JM. Risk of Multiple Sclerosis After a Clinically Isolated Syndrome: From Magnetic Resonance Imaging to Oligoclonal Bands to Activated T Cells. JAMA Neurol. 2017 Jan 03. PMID: 28055077.
      View in: PubMed
    2. Block VJ, Lizée A, Crabtree-Hartman E, Bevan CJ, Graves JS, Bove R, Green AJ, Nourbakhsh B, Tremblay M, Gourraud PA, Ng MY, Pletcher MJ, Olgin JE, Marcus GM, Allen DD, Cree BA, Gelfand JM. Continuous daily assessment of multiple sclerosis disability using remote step count monitoring. J Neurol. 2016 Nov 28. PMID: 27896433.
      View in: PubMed
    3. Miloslavsky EM, Naden RP, Bijlsma JW, Brogan PA, Brown ES, Brunetta P, Buttgereit F, Choi HK, DiCaire JF, Gelfand J, Heaney LG, Lightstone L, Lu N, Murrell DF, Petri M, Rosenbaum JT, Saag KS, Urowitz MB, Winthrop KL, Stone JH, et al. Development of a Glucocorticoid Toxicity Index (GTI) using multicriteria decision analysis. Ann Rheum Dis. 2016 Jul 29. PMID: 27474764.
      View in: PubMed
    4. Cree B, Gourraud PA, Oksenberg JR, Bevan C, Crabtree-Hartman E, Gelfand J, Goodin DS, Graves J, Green AJ, Mowry E, Okuda DT, Pelletier D, von Büdingen HC, Zamvil SS, Agrawal A, Caillier S, Ciocca C, Gomez R, Kanner R, Lincoln R, Lizee A, Qualley P, Santaniello A, Suleiman L, Bucci M, Panara V, Papinutto N, Stern WA, Zhu AH, Cutter GR, Baranzini S, Henry RG, Hauser SL, et al. Long-term evolution of multiple sclerosis disability in the treatment era. Ann Neurol. 2016 Jul 27. PMID: 27464262.
      View in: PubMed
    5. Balk LJ, Cruz-Herranz A, Albrecht P, Arnow S, Gelfand J, Tewarie P, Killestein J, Uitdehaag BM, Petzold A, Green AJ. Timing of retinal neuronal and axonal loss in MS: a longitudinal OCT study. J Neurol. 2016 Jul; 263(7):1323-31. PMID: 27142714.
      View in: PubMed
    6. Block VA, Pitsch E, Tahir P, Cree BA, Allen DD, Gelfand JM. Remote Physical Activity Monitoring in Neurological Disease: A Systematic Review. PLoS One. 2016; 11(4):e0154335. PMID: 27124611.
      View in: PubMed
    7. Graus F, Titulaer MJ, Balu R, Benseler S, Bien CG, Cellucci T, Cortese I, Dale RC, Gelfand J, Geschwind M, Glaser CA, Honnorat J, Höftberger R, Iizuka T, Irani SR, Lancaster E, Leypoldt F, Prüss H, Rae-Grant A, Reindl M, Rosenfeld MR, Rostásy K, Saiz A, Venkatesan A, Vincent A, Wandinger KP, Waters P, Dalmau J. A clinical approach to diagnosis of autoimmune encephalitis. Lancet Neurol. 2016 Apr; 15(4):391-404. PMID: 26906964.
      View in: PubMed
    8. Schubert RD, Wood M, Levin MH, Perry A, Gelfand JM. The severe side of the IgG4-related hypertrophic pachymeningitis disease spectrum. Neurol Neuroimmunol Neuroinflamm. 2016 Feb; 3(1):e197. PMID: 26770998.
      View in: PubMed
    9. Gelfand JM. One Brain, Two Specialties, Converging Mechanisms: Neuronal Autoantibodies as a Rare Cause of Postpartum Psychosis. Am J Psychiatry. 2015 Sep 1; 172(9):824-6. PMID: 26324300.
      View in: PubMed
    10. Gelfand J . Neurosarcoidosis. In: Samuels M, editor. Scientific American Neurology. 2015.
    11. Schlaeger R, Papinutto N, Zhu AH, Lobach IV, Bevan CJ, Bucci M, Castellano A, Gelfand JM, Graves JS, Green AJ, Jordan KM, Keshavan A, Panara V, Stern WA, von Büdingen HC, Waubant E, Goodin DS, Cree BA, Hauser SL, Henry RG. Association Between Thoracic Spinal Cord Gray Matter Atrophy and Disability in Multiple Sclerosis. JAMA Neurol. 2015 Aug; 72(8):897-904. PMID: 26053119.
      View in: PubMed
    12. Höftberger R, van Sonderen A, Leypoldt F, Houghton D, Geschwind M, Gelfand J, Paredes M, Sabater L, Saiz A, Titulaer MJ, Graus F, Dalmau J. Encephalitis and AMPA receptor antibodies: Novel findings in a case series of 22 patients. Neurology. 2015 Jun 16; 84(24):2403-12. PMID: 25979696; PMCID: PMC4478035 [Available on 06/16/16].
    13. Gelfand, JM. Douglas, VC. Harrison's Principles of Internal Medicine. 19th Edition. Edited by Dennis L. Kasper, Anthony S. Fauci, Stephen L. Hauser, Dan L. Longo, J. Larry Jameson, Joseph Loscalzo. Chapter 29: Fatigue. 2015; 151-153.
    14. Bevan C, Gelfand JM. Therapeutic management of severe relapses in multiple sclerosis. Curr Treat Options Neurol. 2015 Apr; 17(4):345. PMID: 25794777.
      View in: PubMed
    15. Gelfand JM, Genrich G, Green AJ, Tihan T, Cree BA. Encephalitis of unclear origin diagnosed by brain biopsy: a diagnostic challenge. JAMA Neurol. 2015 Jan; 72(1):66-72. PMID: 25365755.
      View in: PubMed
    16. Gourraud PA, Henry RG, Cree BA, Crane JC, Lizee A, Olson MP, Santaniello AV, Datta E, Zhu AH, Bevan CJ, Gelfand JM, Graves JS, Goodin DS, Green AJ, von Büdingen HC, Waubant E, Zamvil SS, Crabtree-Hartman E, Nelson S, Baranzini SE, Hauser SL. Precision medicine in chronic disease management: The multiple sclerosis BioScreen. Ann Neurol. 2014 Nov; 76(5):633-42. PMID: 25263997; PMCID: PMC4214886.
    17. Gelfand JM, Cotter J, Klingman J, Huang EJ, Cree BA. Massive CNS monocytic infiltration at autopsy in an alemtuzumab-treated patient with NMO. Neurol Neuroimmunol Neuroinflamm. 2014 Oct; 1(3):e34. PMID: 25340086; PMCID: PMC4204228.
    18. Naasan G, Irani SR, Bettcher BM, Geschwind MD, Gelfand JM. Episodic bradycardia as neurocardiac prodrome to voltage-gated potassium channel complex/leucine-rich, glioma inactivated 1 antibody encephalitis. JAMA Neurol. 2014 Oct; 71(10):1300-4. PMID: 25133690; PMCID: PMC4474144.
    19. Ward ME, Taubes A, Chen R, Miller BL, Sephton CF, Gelfand JM, Minami S, Boscardin J, Martens LH, Seeley WW, Yu G, Herz J, Filiano AJ, Arrant AE, Roberson ED, Kraft TW, Farese RV, Green A, Gan L. Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD. J Exp Med. 2014 Sep 22; 211(10):1937-45. PMID: 25155018; PMCID: PMC4172214.
    20. Schlaeger R, Papinutto N, Panara V, Bevan C, Lobach IV, Bucci M, Caverzasi E, Gelfand JM, Green AJ, Jordan KM, Stern WA, von Büdingen HC, Waubant E, Zhu AH, Goodin DS, Cree BA, Hauser SL, Henry RG. Spinal cord gray matter atrophy correlates with multiple sclerosis disability. Ann Neurol. 2014 Oct; 76(4):568-80. PMID: 25087920.
      View in: PubMed
    21. Irani SR, Gelfand JM, Al-Diwani A, Vincent A. Cell-surface central nervous system autoantibodies: clinical relevance and emerging paradigms. Ann Neurol. 2014 Aug; 76(2):168-84. PMID: 24930434; PMCID: PMC4141019.
    22. Bettcher BM, Gelfand JM, Irani SR, Neuhaus J, Forner S, Hess CP, Geschwind MD. More than memory impairment in voltage-gated potassium channel complex encephalopathy. Eur J Neurol. 2014 Oct; 21(10):1301-10. PMID: 24981998; PMCID: PMC4162838.
    23. Irani SR, Gelfand JM, Bettcher BM, Singhal NS, Geschwind MD. Effect of rituximab in patients with leucine-rich, glioma-inactivated 1 antibody-associated encephalopathy. JAMA Neurol. 2014 Jul 1; 71(7):896-900. PMID: 24842754; PMCID: PMC4477824.
    24. Judson MA, Costabel U, Drent M, Wells A, Maier L, Koth L, Shigemitsu H, Culver DA, Gelfand J, Valeyre D, Sweiss N, Crouser E, Morgenthau AS, Lower EE, Azuma A, Ishihara M, Morimoto S, Tetsuo Yamaguchi T, Shijubo N, Grutters JC, Rosenbach M, Li HP, Rottoli P, Inoue Y, Prasse A, Baughman RP, Organ Assessment Instrument Investigators TW. The WASOG Sarcoidosis Organ Assessment Instrument: An update of a previous clinical tool. Sarcoidosis Vasc Diffuse Lung Dis. 2014; 31(1):19-27. PMID: 24751450.
      View in: PubMed
    25. Gelfand JM. Multiple sclerosis: diagnosis, differential diagnosis, and clinical presentation. Handb Clin Neurol. 2014; 122:269-90. PMID: 24507522.
      View in: PubMed
    26. Gelfand JM, Cree BA, Nolan R, Arnow S, Green AJ. Microcystic inner nuclear layer abnormalities and neuromyelitis optica. JAMA Neurol. 2013 May; 70(5):629-33. PMID: 23529376.
      View in: PubMed
    27. Gelfand AA, Gelfand JM, Goadsby PJ. Migraine and multiple sclerosis: Epidemiology and approach to treatment. Mult Scler Relat Disord. 2013 Apr; 2(2):73-9. PMID: 25877626.
      View in: PubMed
    28. Boronat A, Gelfand JM, Gresa-Arribas N, Jeong HY, Walsh M, Roberts K, Martinez-Hernandez E, Rosenfeld MR, Balice-Gordon R, Graus F, Rudy B, Dalmau J. Encephalitis and antibodies to dipeptidyl-peptidase-like protein-6, a subunit of Kv4.2 potassium channels. Ann Neurol. 2013 Jan; 73(1):120-8. PMID: 23225603; PMCID: PMC3563722.
    29. Nolan R, Gelfand JM, Green AJ. Fingolimod treatment in multiple sclerosis leads to increased macular volume. Neurology. 2013 Jan 8; 80(2):139-44. PMID: 23223539; PMCID: PMC3589191.
    30. Saidha S, Sotirchos ES, Ibrahim MA, Crainiceanu CM, Gelfand JM, Sepah YJ, Ratchford JN, Oh J, Seigo MA, Newsome SD, Balcer LJ, Frohman EM, Green AJ, Nguyen QD, Calabresi PA. Microcystic macular oedema, thickness of the inner nuclear layer of the retina, and disease characteristics in multiple sclerosis: a retrospective study. Lancet Neurol. 2012 Nov; 11(11):963-72. PMID: 23041237; PMCID: PMC3533139.
    31. Gelfand JM, Goodin DS, Boscardin WJ, Nolan R, Cuneo A, Green AJ. Retinal axonal loss begins early in the course of multiple sclerosis and is similar between progressive phenotypes. PLoS One. 2012; 7(5):e36847. PMID: 22666330; PMCID: PMC3359324.
    32. Gelfand JM, Nolan R, Schwartz DM, Graves J, Green AJ. Microcystic macular oedema in multiple sclerosis is associated with disease severity. Brain. 2012 Jun; 135(Pt 6):1786-93. PMID: 22539259; PMCID: PMC3359753.
    33. Gelfand J . Neurology Now. Should I see a neurologist for sarcoidosis?. 2012; 1(8):31.
    34. Villoslada P, Cuneo A, Gelfand J, Hauser SL, Green A. Color vision is strongly associated with retinal thinning in multiple sclerosis. Mult Scler. 2012 Jul; 18(7):991-9. PMID: 22291035.
      View in: PubMed
    35. Gelfand AA, Gelfand JM, Prabakhar P, Goadsby PJ. Ophthalmoplegic "migraine" or recurrent ophthalmoplegic cranial neuropathy: new cases and a systematic review. J Child Neurol. 2012 Jun; 27(6):759-66. PMID: 22241707; PMCID: PMC3562350.
    36. Gelfand JM, Cree BA, McElroy J, Oksenberg J, Green R, Mowry EM, Miller JW, Hauser SL, Green AJ. Vitamin D in African Americans with multiple sclerosis. Neurology. 2011 May 24; 76(21):1824-30. PMID: 21606454; PMCID: PMC3100123.
    37. Gelfand JM, Duncan JL, Racine CA, Gillum LA, Chin CT, Zhang Y, Zhang Q, Wong LJ, Roorda A, Green AJ. Heterogeneous patterns of tissue injury in NARP syndrome. J Neurol. 2011 Mar; 258(3):440-8. PMID: 20953793; PMCID: PMC3068520.
    38. Dhand A, Nakagawa K, Nagpal S, Gelfand JM, Kim AS, Smith WS, Tihan T. Cardiac rupture after intravenous t-PA administration in acute ischemic stroke. Neurocrit Care. 2010 Oct; 13(2):261-2. PMID: 20697837.
      View in: PubMed
    39. Gelfand JM, Wintermark M, Josephson SA. Cerebral perfusion-CT patterns following seizure. Eur J Neurol. 2010 Apr; 17(4):594-601. PMID: 19968701.
      View in: PubMed
    40. Gelfand JM, Nelson AB, Fross RD, Glass GA. Speech-activated myoclonus masquerading as stuttering. Neurology. 2009 Jun 2; 72(22):1964. PMID: 19487657.
      View in: PubMed
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