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    Lily Jan, PhD

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentPhysiology
    Address1550 4th Street, Bldg 19B
    San Francisco CA 94158
    Phone415-476-8748
      Other Positions
      TitleHoward Hughes Medical Institute investigator


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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Bagley JA, Yan Z, Zhang W, Wildonger J, Jan LY, Jan YN. Double-bromo and extraterminal (BET) domain proteins regulate dendrite morphology and mechanosensory function. Genes Dev. 2014 Sep 1; 28(17):1940-56.
        View in: PubMed
      2. Huang X, Jan LY. Targeting potassium channels in cancer. J Cell Biol. 2014 Jul 21; 206(2):151-62.
        View in: PubMed
      3. Tien J, Peters CJ, Wong XM, Cheng T, Jan YN, Jan LY, Yang H. A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity. Elife. 2014; 3.
        View in: PubMed
      4. Hong T, Yang H, Zhang SS, Cho HC, Kalashnikova M, Sun B, Zhang H, Bhargava A, Grabe M, Olgin J, Gorelik J, Marbán E, Jan LY, Shaw RM. Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia. Nat Med. 2014 Jun; 20(6):624-32.
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      5. Yu D, Gustafson WC, Han C, Lafaye C, Noirclerc-Savoye M, Ge WP, Thayer DA, Huang H, Kornberg TB, Royant A, Jan LY, Jan YN, Weiss WA, Shu X. An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging. Nat Commun. 2014; 5:3626.
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      6. Parrish JZ, Kim CC, Tang L, Bergquist S, Wang T, Derisi JL, Jan LY, Jan YN, Davis GW. Krüppel mediates the selective rebalancing of ion channel expression. Neuron. 2014 May 7; 82(3):537-44.
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      7. Rumpf S, Bagley JA, Thompson-Peer KL, Zhu S, Gorczyca D, Beckstead RB, Jan LY, Jan YN. Drosophila Valosin-Containing Protein is required for dendrite pruning through a regulatory role in mRNA metabolism. Proc Natl Acad Sci U S A. 2014 May 20; 111(20):7331-6.
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      8. Jan L. Lily Jan. Curr Biol. 2014 Mar 17; 24(6):R212-3.
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      9. Han C, Song Y, Xiao H, Wang D, Franc NC, Jan LY, Jan YN. Epidermal cells are the primary phagocytes in the fragmentation and clearance of degenerating dendrites in Drosophila. Neuron. 2014 Feb 5; 81(3):544-60.
        View in: PubMed
      10. Kim WJ, Jan LY, Jan YN. A PDF/NPF Neuropeptide Signaling Circuitry of Male Drosophila melanogaster Controls Rival-Induced Prolonged Mating. Neuron. 2013 Dec 4; 80(5):1190-205.
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      11. Yuan Q, Song Y, Yang CH, Jan LY, Jan YN. Female contact modulates male aggression via a sexually dimorphic GABAergic circuit in Drosophila. Nat Neurosci. 2014 Jan; 17(1):81-8.
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      12. Wong XM, Younger S, Peters CJ, Jan YN, Jan LY. Subdued, a TMEM16 family Ca2+-activated Cl- channel in Drosophila melanogaster with an unexpected role in host defense. Elife. 2013; 2(0).
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      13. Isacoff EY, Jan LY, Minor DL. Conduits of Life's Spark: A Perspective on Ion Channel Research since the Birth of Neuron. Neuron. 2013 Oct 30; 80(3):658-74.
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      14. Sun Y, Dong Z, Jin T, Ang KH, Huang M, Haston KM, Peng J, Zhong TP, Finkbeiner S, Weiss WA, Arkin MR, Jan LY, Guo S. Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells. Elife. 2013; 2:e00508.
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      15. Han TW, Jan LY. Making antisense of pain. Nat Neurosci. 2013 Aug; 16(8):986-7.
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      16. Zhang W, Yan Z, Jan LY, Jan YN. Sound response mediated by the TRP channels NOMPC, NANCHUNG, and INACTIVE in chordotonal organs of Drosophila larvae. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):13612-7.
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      17. Huang F, Wang X, Ostertag EM, Nuwal T, Huang B, Jan YN, Basbaum AI, Jan LY. TMEM16C facilitates Na(+)-activated K+ currents in rat sensory neurons and regulates pain processing. Nat Neurosci. 2013 Sep; 16(9):1284-90.
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      18. Tien J, Lee HY, Minor DL, Jan YN, Jan LY. Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC). Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):6352-7.
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      19. Thayer DA, Jan YN, Jan LY. Increased neuronal activity fragments the Golgi complex. Proc Natl Acad Sci U S A. 2013 Jan 22; 110(4):1482-7.
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      20. Yan Z, Zhang W, He Y, Gorczyca D, Xiang Y, Cheng LE, Meltzer S, Jan LY, Jan YN. Drosophila NOMPC is a mechanotransduction channel subunit for gentle-touch sensation. Nature. 2013 Jan 10; 493(7431):221-5.
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      21. Ori-McKenney KM, Jan LY, Jan YN. Golgi outposts shape dendrite morphology by functioning as sites of acentrosomal microtubule nucleation in neurons. Neuron. 2012 Dec 6; 76(5):921-30.
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      22. Yang H, Kim A, David T, Palmer D, Jin T, Tien J, Huang F, Cheng T, Coughlin SR, Jan YN, Jan LY. TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation. Cell. 2012 Sep 28; 151(1):111-22.
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      23. Huang F, Zhang H, Wu M, Yang H, Kudo M, Peters CJ, Woodruff PG, Solberg OD, Donne ML, Huang X, Sheppard D, Fahy JV, Wolters PJ, Hogan BL, Finkbeiner WE, Li M, Jan YN, Jan LY, Rock JR. Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proc Natl Acad Sci U S A. 2012 Oct 2; 109(40):16354-9.
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      24. Yang SB, Tien AC, Boddupalli G, Xu AW, Jan YN, Jan LY. Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons. Neuron. 2012 Aug 9; 75(3):425-36.
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      25. Huang X, Dubuc AM, Hashizume R, Berg J, He Y, Wang J, Chiang C, Cooper MK, Northcott PA, Taylor MD, Barnes MJ, Tihan T, Chen J, Hackett CS, Weiss WA, James CD, Rowitch DH, Shuman MA, Jan YN, Jan LY. Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes Dev. 2012 Aug 15; 26(16):1780-96.
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      26. Song Y, Ori-McKenney KM, Zheng Y, Han C, Jan LY, Jan YN. Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten and microRNA bantam. Genes Dev. 2012 Jul 15; 26(14):1612-25.
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      27. Kim WJ, Jan LY, Jan YN. Contribution of visual and circadian neural circuits to memory for prolonged mating induced by rivals. Nat Neurosci. 2012 Jun; 15(6):876-83.
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      28. Huang WC, Xiao S, Huang F, Harfe BD, Jan YN, Jan LY. Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons. Neuron. 2012 Apr 12; 74(1):179-92.
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      29. Lee HY, Jan LY. Fragile X syndrome: mechanistic insights and therapeutic avenues regarding the role of potassium channels. Curr Opin Neurobiol. 2012 Oct; 22(5):887-94.
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      30. Ge WP, Miyawaki A, Gage FH, Jan YN, Jan LY. Local generation of glia is a major astrocyte source in postnatal cortex. Nature. 2012 Apr 19; 484(7394):376-80.
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      31. Ultanir SK, Hertz NT, Li G, Ge WP, Burlingame AL, Pleasure SJ, Shokat KM, Jan LY, Jan YN. Chemical genetic identification of NDR1/2 kinase substrates AAK1 and Rabin8 Uncovers their roles in dendrite arborization and spine development. Neuron. 2012 Mar 22; 73(6):1127-42.
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      32. Jan LY, Jan YN. Voltage-gated potassium channels and the diversity of electrical signalling. J Physiol. 2012 Jun 1; 590(Pt 11):2591-9.
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      33. Berg J, Yang H, Jan LY. Ca2+-activated Cl- channels at a glance. J Cell Sci. 2012 Mar 15; 125(Pt 6):1367-71.
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      34. Yang SB, Mclemore KD, Tasic B, Luo L, Jan YN, Jan LY. Kv1.1-dependent control of hippocampal neuron number as revealed by mosaic analysis with double markers. J Physiol. 2012 Jun 1; 590(Pt 11):2645-58.
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      35. Han C, Wang D, Soba P, Zhu S, Lin X, Jan LY, Jan YN. Integrins regulate repulsion-mediated dendritic patterning of drosophila sensory neurons by restricting dendrites in a 2D space. Neuron. 2012 Jan 12; 73(1):64-78.
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      36. Zhu S, Barshow S, Wildonger J, Jan LY, Jan YN. Ets transcription factor Pointed promotes the generation of intermediate neural progenitors in Drosophila larval brains. Proc Natl Acad Sci U S A. 2011 Dec 20; 108(51):20615-20.
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      37. Yang SB, Lee HY, Young DM, Tien AC, Rowson-Baldwin A, Shu YY, Jan YN, Jan LY. Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity. J Mol Med (Berl). 2012 May; 90(5):575-85.
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      38. Lee HY, Ge WP, Huang W, He Y, Wang GX, Rowson-Baldwin A, Smith SJ, Jan YN, Jan LY. Bidirectional regulation of dendritic voltage-gated potassium channels by the fragile X mental retardation protein. Neuron. 2011 Nov 17; 72(4):630-42.
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      39. Huang F, Wong X, Jan LY. International Union of Basic and Clinical Pharmacology. LXXXV: calcium-activated chloride channels. Pharmacol Rev. 2012 Jan; 64(1):1-15.
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      40. Lee SB, Bagley JA, Lee HY, Jan LY, Jan YN. Pathogenic polyglutamine proteins cause dendrite defects associated with specific actin cytoskeletal alterations in Drosophila. Proc Natl Acad Sci U S A. 2011 Oct 4; 108(40):16795-800.
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      41. Yuan Q, Xiang Y, Yan Z, Han C, Jan LY, Jan YN. Light-induced structural and functional plasticity in Drosophila larval visual system. Science. 2011 Sep 9; 333(6048):1458-62.
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      42. Lee RM, Ryu RH, Jeong SW, Oh SJ, Huang H, Han JS, Lee CH, Lee CJ, Jan LY, Jeong SM. Isolation and Expression Profile of the Ca-Activated Chloride Channel-like Membrane Protein 6 Gene in Xenopus laevis. Lab Anim Res. 2011 Jun; 27(2):109-16.
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      43. Ouyang Y, Petritsch C, Wen H, Jan L, Jan YN, Lu B. Dronc caspase exerts a non-apoptotic function to restrain phospho-Numb-induced ectopic neuroblast formation in Drosophila. Development. 2011 Jun; 138(11):2185-96.
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      44. Han C, Jan LY, Jan YN. Enhancer-driven membrane markers for analysis of nonautonomous mechanisms reveal neuron-glia interactions in Drosophila. Proc Natl Acad Sci U S A. 2011 Jun 7; 108(23):9673-8.
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      45. Ryu RH, Oh SJ, Lee RM, Jeong SW, Jan LY, Lee CH, Lee CJ, Jeong SM. Cloning and heterologous expression of new xANO2 from Xenopus laevis. Biochem Biophys Res Commun. 2011 May 20; 408(4):559-65.
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      46. Ye B, Kim JH, Yang L, McLachlan I, Younger S, Jan LY, Jan YN. Differential regulation of dendritic and axonal development by the novel Krüppel-like factor Dar1. J Neurosci. 2011 Mar 2; 31(9):3309-19.
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      47. Rumpf S, Lee SB, Jan LY, Jan YN. Neuronal remodeling and apoptosis require VCP-dependent degradation of the apoptosis inhibitor DIAP1. Development. 2011 Mar; 138(6):1153-60.
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      48. Xiang Y, Yuan Q, Vogt N, Looger LL, Jan LY, Jan YN. Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall. Nature. 2010 Dec 16; 468(7326):921-6.
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      49. Thayer DA, Jan LY. Mechanisms of distribution and targeting of neuronal ion channels. Curr Opin Drug Discov Devel. 2010 Sep; 13(5):559-67.
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      50. Cheng LE, Song W, Looger LL, Jan LY, Jan YN. The role of the TRP channel NompC in Drosophila larval and adult locomotion. Neuron. 2010 Aug 12; 67(3):373-80.
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      51. Zhou W, Jan L. A twist on potassium channel gating. Cell. 2010 Jun 11; 141(6):920-2.
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      52. Young DM, Schenk AK, Yang SB, Jan YN, Jan LY. Altered ultrasonic vocalizations in a tuberous sclerosis mouse model of autism. Proc Natl Acad Sci U S A. 2010 Jun 15; 107(24):11074-9.
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      53. Jan YN, Jan LY. Branching out: mechanisms of dendritic arborization. Nat Rev Neurosci. 2010 May; 11(5):316-28.
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      54. Huang F, Rock JR, Harfe BD, Cheng T, Huang X, Jan YN, Jan LY. Studies on expression and function of the TMEM16A calcium-activated chloride channel. Proc Natl Acad Sci U S A. 2009 Dec 15; 106(50):21413-8.
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      55. Parrish JZ, Xu P, Kim CC, Jan LY, Jan YN. The microRNA bantam functions in epithelial cells to regulate scaling growth of dendrite arbors in drosophila sensory neurons. Neuron. 2009 Sep 24; 63(6):788-802.
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      56. Bultje RS, Castaneda-Castellanos DR, Jan LY, Jan YN, Kriegstein AR, Shi SH. Mammalian Par3 regulates progenitor cell asymmetric division via notch signaling in the developing neocortex. Neuron. 2009 Jul 30; 63(2):189-202.
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      57. Lee HH, Jan LY, Jan YN. Drosophila IKK-related kinase Ik2 and Katanin p60-like 1 regulate dendrite pruning of sensory neuron during metamorphosis. Proc Natl Acad Sci U S A. 2009 Apr 14; 106(15):6363-8.
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      58. Xiao S, Jan LY. A gate keeper for axonal transport. Cell. 2009 Mar 20; 136(6):996-8.
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      59. Yang CH, Rumpf S, Xiang Y, Gordon MD, Song W, Jan LY, Jan YN. Control of the postmating behavioral switch in Drosophila females by internal sensory neurons. Neuron. 2009 Feb 26; 61(4):519-26.
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      60. Chung HJ, Qian X, Ehlers M, Jan YN, Jan LY. Neuronal activity regulates phosphorylation-dependent surface delivery of G protein-activated inwardly rectifying potassium channels. Proc Natl Acad Sci U S A. 2009 Jan 13; 106(2):629-34.
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      61. Chung HJ, Ge WP, Qian X, Wiser O, Jan YN, Jan LY. G protein-activated inwardly rectifying potassium channels mediate depotentiation of long-term potentiation. Proc Natl Acad Sci U S A. 2009 Jan 13; 106(2):635-40.
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      62. Ge WP, Zhou W, Luo Q, Jan LY, Jan YN. Dividing glial cells maintain differentiated properties including complex morphology and functional synapses. Proc Natl Acad Sci U S A. 2009 Jan 6; 106(1):328-33.
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      63. Schroeder BC, Cheng T, Jan YN, Jan LY. Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell. 2008 Sep 19; 134(6):1019-29.
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      64. Wildonger J, Jan LY, Jan YN. The Tsc1-Tsc2 complex influences neuronal polarity by modulating TORC1 activity and SAD levels. Genes Dev. 2008 Sep 15; 22(18):2447-53.
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      65. Zheng Y, Wildonger J, Ye B, Zhang Y, Kita A, Younger SH, Zimmerman S, Jan LY, Jan YN. Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons. Nat Cell Biol. 2008 Oct; 10(10):1172-80.
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      66. Yang SB, Jan LY. Thrilling moment of an inhibitory channel. Neuron. 2008 Jun 26; 58(6):823-4.
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      67. Chi NC, Shaw RM, Jungblut B, Huisken J, Ferrer T, Arnaout R, Scott I, Beis D, Xiao T, Baier H, Jan LY, Tristani-Firouzi M, Stainier DY. Genetic and physiologic dissection of the vertebrate cardiac conduction system. PLoS Biol. 2008 May 13; 6(5):e109.
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      68. Yang CH, Belawat P, Hafen E, Jan LY, Jan YN. Drosophila egg-laying site selection as a system to study simple decision-making processes. Science. 2008 Mar 21; 319(5870):1679-83.
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      69. Jin T, Sui JL, Rosenhouse-Dantsker A, Chan KW, Jan LY, Logothetis DE. Stoichiometry of Kir channels with phosphatidylinositol bisphosphate. Channels (Austin). 2008 Jan-Feb; 2(1):19-33.
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      70. Chi NC, Shaw RM, De Val S, Kang G, Jan LY, Black BL, Stainier DY. Foxn4 directly regulates tbx2b expression and atrioventricular canal formation. Genes Dev. 2008 Mar 15; 22(6):734-9.
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      71. Jan YN, Jan L. Retrospective: Seymour Benzer (1921-2007). Science. 2008 Jan 4; 319(5859):45.
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      72. Haass FA, Jonikas M, Walter P, Weissman JS, Jan YN, Jan LY, Schuldiner M. Identification of yeast proteins necessary for cell-surface function of a potassium channel. Proc Natl Acad Sci U S A. 2007 Nov 13; 104(46):18079-84.
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      73. Ye B, Zhang Y, Song W, Younger SH, Jan LY, Jan YN. Growing dendrites and axons differ in their reliance on the secretory pathway. Cell. 2007 Aug 24; 130(4):717-29.
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      74. Chang W, Tu C, Cheng Z, Rodriguez L, Chen TH, Gassmann M, Bettler B, Margeta M, Jan LY, Shoback D. Complex formation with the Type B gamma-aminobutyric acid receptor affects the expression and signal transduction of the extracellular calcium-sensing receptor. Studies with HEK-293 cells and neurons. J Biol Chem. 2007 Aug 24; 282(34):25030-40.
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      75. Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, Li HS, Jan LY, Jan YN, Rakic P, Sestan N. Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci. 2007 Jul; 10(7):819-27.
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      76. Soba P, Zhu S, Emoto K, Younger S, Yang SJ, Yu HH, Lee T, Jan LY, Jan YN. Drosophila sensory neurons require Dscam for dendritic self-avoidance and proper dendritic field organization. Neuron. 2007 May 3; 54(3):403-16.
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      77. Parrish JZ, Emoto K, Jan LY, Jan YN. Polycomb genes interact with the tumor suppressor genes hippo and warts in the maintenance of Drosophila sensory neuron dendrites. Genes Dev. 2007 Apr 15; 21(8):956-72.
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      78. Song W, Onishi M, Jan LY, Jan YN. Peripheral multidendritic sensory neurons are necessary for rhythmic locomotion behavior in Drosophila larvae. Proc Natl Acad Sci U S A. 2007 Mar 20; 104(12):5199-204.
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      79. Gong Q, Weide M, Huntsman C, Xu Z, Jan LY, Ma D. Identification and characterization of a new class of trafficking motifs for controlling clathrin-independent internalization and recycling. J Biol Chem. 2007 Apr 27; 282(17):13087-97.
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      80. Shaw RM, Fay AJ, Puthenveedu MA, von Zastrow M, Jan YN, Jan LY. Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions. Cell. 2007 Feb 9; 128(3):547-60.
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      81. Katarina K, Daniela P, Peter N, Marianna R, Pavlina C, Stepanka P, Jan L, Ludmila T, Michal A, Marie C. HLA, NFKB1 and NFKBIA gene polymorphism profile in autoimmune diabetes mellitus patients. Exp Clin Endocrinol Diabetes. 2007 Feb; 115(2):124-9.
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      82. Grueber WB, Ye B, Yang CH, Younger S, Borden K, Jan LY, Jan YN. Projections of Drosophila multidendritic neurons in the central nervous system: links with peripheral dendrite morphology. Development. 2007 Jan; 134(1):55-64.
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      83. Grabe M, Lai HC, Jain M, Jan YN, Jan LY. Structure prediction for the down state of a potassium channel voltage sensor. Nature. 2007 Feb 1; 445(7127):550-3.
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      84. Chung HJ, Jan LY. Channeling to the nucleus. Neuron. 2006 Dec 21; 52(6):937-40.
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      85. Kuo CT, Mirzadeh Z, Soriano-Navarro M, Rasin M, Wang D, Shen J, Sestan N, Garcia-Verdugo J, Alvarez-Buylla A, Jan LY, Jan YN. Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche. Cell. 2006 Dec 15; 127(6):1253-64.
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      86. Gu C, Zhou W, Puthenveedu MA, Xu M, Jan YN, Jan LY. The microtubule plus-end tracking protein EB1 is required for Kv1 voltage-gated K+ channel axonal targeting. Neuron. 2006 Dec 7; 52(5):803-16.
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      87. Fay AJ, Qian X, Jan YN, Jan LY. SK channels mediate NADPH oxidase-independent reactive oxygen species production and apoptosis in granulocytes. Proc Natl Acad Sci U S A. 2006 Nov 14; 103(46):17548-53.
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      88. Ja WW, Wiser O, Austin RJ, Jan LY, Roberts RW. Turning G proteins on and off using peptide ligands. ACS Chem Biol. 2006 Oct 24; 1(9):570-4.
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      89. Ye B, Zhang YW, Jan LY, Jan YN. The secretory pathway and neuron polarization. J Neurosci. 2006 Oct 18; 26(42):10631-2.
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      90. Raab-Graham KF, Haddick PC, Jan YN, Jan LY. Activity- and mTOR-dependent suppression of Kv1.1 channel mRNA translation in dendrites. Science. 2006 Oct 6; 314(5796):144-8.
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      91. Kim MD, Jan LY, Jan YN. The bHLH-PAS protein Spineless is necessary for the diversification of dendrite morphology of Drosophila dendritic arborization neurons. Genes Dev. 2006 Oct 15; 20(20):2806-19.
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      92. Grabe M, Bichet D, Qian X, Jan YN, Jan LY. K+ channel selectivity depends on kinetic as well as thermodynamic factors. Proc Natl Acad Sci U S A. 2006 Sep 26; 103(39):14361-6.
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      93. Bichet D, Grabe M, Jan YN, Jan LY. Electrostatic interactions in the channel cavity as an important determinant of potassium channel selectivity. Proc Natl Acad Sci U S A. 2006 Sep 26; 103(39):14355-60.
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      94. Emoto K, Parrish JZ, Jan LY, Jan YN. The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance. Nature. 2006 Sep 14; 443(7108):210-3.
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      95. Kuo CT, Zhu S, Younger S, Jan LY, Jan YN. Identification of E2/E3 ubiquitinating enzymes and caspase activity regulating Drosophila sensory neuron dendrite pruning. Neuron. 2006 Aug 3; 51(3):283-90.
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      96. Lai HC, Jan LY. The distribution and targeting of neuronal voltage-gated ion channels. Nat Rev Neurosci. 2006 Jul; 7(7):548-62.
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      97. Chung HJ, Jan YN, Jan LY. Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains. Proc Natl Acad Sci U S A. 2006 Jun 6; 103(23):8870-5.
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      98. Wiser O, Qian X, Ehlers M, Ja WW, Roberts RW, Reuveny E, Jan YN, Jan LY. Modulation of basal and receptor-induced GIRK potassium channel activity and neuronal excitability by the mammalian PINS homolog LGN. Neuron. 2006 May 18; 50(4):561-73.
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      99. Parrish JZ, Kim MD, Jan LY, Jan YN. Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev. 2006 Apr 1; 20(7):820-35.
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      100. Kubo Y, Adelman JP, Clapham DE, Jan LY, Karschin A, Kurachi Y, Lazdunski M, Nichols CG, Seino S, Vandenberg CA. International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels. Pharmacol Rev. 2005 Dec; 57(4):509-26.
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      101. Surti TS, Huang L, Jan YN, Jan LY, Cooper EC. Identification by mass spectrometry and functional characterization of two phosphorylation sites of KCNQ2/KCNQ3 channels. Proc Natl Acad Sci U S A. 2005 Dec 6; 102(49):17828-33.
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      102. Huang CS, Shi SH, Ule J, Ruggiu M, Barker LA, Darnell RB, Jan YN, Jan LY. Common molecular pathways mediate long-term potentiation of synaptic excitation and slow synaptic inhibition. Cell. 2005 Oct 7; 123(1):105-18.
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      103. Kuo CT, Jan LY, Jan YN. Dendrite-specific remodeling of Drosophila sensory neurons requires matrix metalloproteases, ubiquitin-proteasome, and ecdysone signaling. Proc Natl Acad Sci U S A. 2005 Oct 18; 102(42):15230-5.
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      104. Lai HC, Grabe M, Jan YN, Jan LY. The S4 voltage sensor packs against the pore domain in the KAT1 voltage-gated potassium channel. Neuron. 2005 Aug 4; 47(3):395-406.
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      105. Surti TS, Jan LY. A potassium channel, the M-channel, as a therapeutic target. Curr Opin Investig Drugs. 2005 Jul; 6(7):704-11.
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      106. Ionescu-Zanetti C, Shaw RM, Seo J, Jan YN, Jan LY, Lee LP. Mammalian electrophysiology on a microfluidic platform. Proc Natl Acad Sci U S A. 2005 Jun 28; 102(26):9112-7.
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      107. Roegiers F, Jan LY, Jan YN. Regulation of membrane localization of Sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs. Mol Biol Cell. 2005 Aug; 16(8):3480-7.
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      108. Cohen BE, Pralle A, Yao X, Swaminath G, Gandhi CS, Jan YN, Kobilka BK, Isacoff EY, Jan LY. A fluorescent probe designed for studying protein conformational change. Proc Natl Acad Sci U S A. 2005 Jan 25; 102(4):965-70.
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      109. Huang EJ, Li H, Tang AA, Wiggins AK, Neve RL, Zhong W, Jan LY, Jan YN. Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization. Genes Dev. 2005 Jan 1; 19(1):138-51.
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      110. Grabe M, Lecar H, Jan YN, Jan LY. A quantitative assessment of models for voltage-dependent gating of ion channels. Proc Natl Acad Sci U S A. 2004 Dec 21; 101(51):17640-5.
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      111. Shi SH, Cheng T, Jan LY, Jan YN. APC and GSK-3beta are involved in mPar3 targeting to the nascent axon and establishment of neuronal polarity. Curr Biol. 2004 Nov 23; 14(22):2025-32.
        View in: PubMed
      112. Emoto K, He Y, Ye B, Grueber WB, Adler PN, Jan LY, Jan YN. Control of dendritic branching and tiling by the Tricornered-kinase/Furry signaling pathway in Drosophila sensory neurons. Cell. 2004 Oct 15; 119(2):245-56.
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      360. Jan YN, Jan LY. Genetic dissection of short-term and long-term facilitation at the Drosophila neuromuscular junction. Proc Natl Acad Sci U S A. 1978 Jan; 75(1):515-9.
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