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    Tejal Desai, PhD

    SchoolUCSF School of Pharmacy
    Address1700 4th Street
    San Francisco CA 94158
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      Collapse Biography 
      Collapse Education and Training
      University of California, San FranciscoPh.D. Graduate Division (Bioengineering)1998
      Collapse Awards and Honors
      Sigma Xi, Scientific Honor Society1994Member
      University of California, San Francisco1994Fellowship of the Regents
      National Science Foundation1995Graduate Fellowship Recipient
      Whitaker Foundation1995Graduate Fellowship in Biomedical Engineering
      University of California, San Francisco1997Graduate Conference Presentation Award
      University of California, San Francisco1997Graduate Dissertation Research Award
      University of California, San Francisco1997Graduate Students Association Travel Award
      Crain's Chicago Business1998Who's Who among America's Teachers
      Crain's Chicago Business199940 Under 40 Award: For Leadership and Innovation
      Technology Review Magazine's Top 100 Young Innovators1999MIT's TR100 Award
      University of Illinois, Chicago, College of Engineering2000Award of Distinction
      National Science Foundation2000CAREER Award
      University of Illinois, Chicago, College of Engineering2000Best Advisor Award
      National Science Foundation2000New Century Scholar Award
      BioMEMS and Nanotechnology Society2001Visionary Science Award
      Frontiers in Engineering, National Academy of Engineering2001Invited Participant
      Johnson and Johnson2002Focused Giving Award
      McGowan Institute2002Award for Contributions to Regenerative Medicine
      EURAND2003Grand Prize Award for Outstanding Research in Oral Drug Delivery
      Massachusetts Institute of Technology2003Globus Indus Technovator Award
      Popular Science2003"Brilliant 10" Top Scientists in the Nation
      Whitaker Leadership Conference2003Invited Conference Participant
      INDIA New England2004Woman of the Year
      World Technology Award2004Award Finalist in Health and Medicine
      Capsugel/Pfizer2004Innovative Aspects of Oral Drug Delivery Award (Paper Competition)
      National Academy of Engineering2004Invited Participant: Keck Futures Initiative: Designing Nanostructure
      INDUS2004Winner of INDUS Top 15
      Women in Engineering Leadership Conference2005Nomination and Award
      Siemens National Competition2005Judge in Nanotechnology
      Lawrence Hall of Science2005Featured Exhibit, Women in Nanotechnology
      EURAND2006Grand Prize Award for Innovative Approaches to Drug Delivery
      2006Rogers Bridging the Gap Award for New Technologies
      University of California, Berkeley2006Distinguished Engineering Alumni Award
      University of California, San Francisco, UCSF/CORO2007Faculty Leadership Collaborative
      Capsugel/Pfizer2007Innovative Aspects of Oral Drug Delivery Award (Two Paper Awards)
      Engineering in Medicine and Biology Society (EMBS)2007Career Award
      7 x 7 Magazine2008San Francisco's Top 40 under 40
      Diversity in Higher Education Journal2008Emerging Scholar Award
      Controlled Release Society2009Awards for Best Papers (Oral and Pharmaceutical Categories)
      IEEE Society2009Senior Member
      Siemens Math, Science, and Technology Competition2009National Judge
      Nature Medicine's 5 Big Ideas for Nanotechnology2009Work Cited
      NIH Biomaterials and Biointerfaces Study Section2010Standing Member
      University of California, San Francisco2010Dean's Citation for Excellence in Teaching
      American Insitute of Medical and Biological Engineering (AIMBE)2011Elected Fellow of American Insitute of Medical and Biological Engineering (AIMBE)
      Wallace H. Coulter Foundation2011Translational Award Recipient
      Whitaker International Scholars2011Review Committee
      Siemens National Competition2011Nanotechnology Judge
      American Association of Colleges of Pharmacy2012Paul Dawson Biotechnology Award
      Invited Participant2013OME Precision Medicine Summit
      Whitaker International Scholars Programs2013Steering Committee
      Scientific American2013Featured Innovator
      Invited Participant2013McKinsey's 3rd Annual Women's Leadership Summit
      Appointed Chair2014Biomaterial and Biointerfaces NIH Study Section
      Brown University School of Engineering2015Brown Engineering Alumni Medal (BEAM)

      Collapse Overview 
      Collapse Overview
      Dr. Desai’s research brings together advanced micro and nanotechnologies, fundamental insight into cellular behavior in engineered environments, and novel pharmacologic delivery approaches to address disease treatment and clinical translation. Currently, her laboratory focuses on four highly interdisciplinary directions: 1. Hierarchical devices for enhanced cellular adhesion and paracellular drug transport; 2. Injectable and flexible nanoporous devices for rate-controlled long term release of therapeutics; 3. Nanostructured coatings and scaffolds for pro-healing implants and in vivo modulation of fibrosis, and 4. Cell-based delivery platforms for autoimmune disease applications. She envisions a future of precision medicine, enabled by advances in nanotechnology, engineering, and cell biology directed to clinical challenges in disease treatment. By taking advantage of our understanding of how cells respond to engineered materials and our ability to fabricate precise structural domains, her lab seeks to design new platforms to overcome existing challenges in therapeutic delivery.

      Collapse Interests
      Nanostructured materials, BioMEMS and Biomedical Nanotechnology, bioengineering, drug delivery (Oral, Ocular, and Implantable), cell encapsulation technologies (Pancreatic and Neurosecretory), tissue engineering (Cardiovascular, Retinal, Corneal, and Bone), three dimensional scaffold and matrix fabrication, medical devices, surface modification and biocompatibility

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      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Muthusubramaniam L, Zaitseva T, Paukshto M, Martin G, Desai T. Effect of collagen nanotopography on keloid fibroblast proliferation and matrix synthesis: implications for dermal wound healing. Tissue Eng Part A. 2014 Oct; 20(19-20):2728-36.
        View in: PubMed PMC4195479
      2. Chirra HD, Shao L, Ciaccio N, Fox CB, Wade JM, Ma A, Desai TA. Planar microdevices for enhanced in vivo retention and oral bioavailability of poorly permeable drugs. Adv Healthc Mater. 2014 Oct; 3(10):1648-54.
        View in: PubMed PMC4256094
      3. Schweicher J, Desai TA. Facile Synthesis of Robust Free-Standing TiO2 Nanotubular Membranes for Biofiltration Applications. J Appl Electrochem. 2014 Mar 1; 44(3):411-418.
        View in: PubMed
      4. Nyitray CE, Chavez MG, Desai TA. Compliant 3D microenvironment improves ß-Cell cluster insulin expression through mechanosensing and ß-catenin signaling. Tissue Eng Part A. 2014 Jul; 20(13-14):1888-95.
        View in: PubMed PMC4085995
      5. Uskokovic V, Desai TA. Simultaneous bactericidal and osteogenic effect of nanoparticulate calcium phosphate powders loaded with clindamycin on osteoblasts infected with Staphylococcus aureus. Mater Sci Eng C Mater Biol Appl. 2014 Apr 1; 37:210-22.
        View in: PubMed PMC3942787
      6. Kurpinski K, Johnson T, Kumar S, Desai T, Li S. Mastering translational medicine: interdisciplinary education for a new generation. Sci Transl Med. 2014 Jan 8; 6(218):218fs2.
        View in: PubMed
      7. Uskokovic V, Desai TA. In vitro analysis of nanoparticulate hydroxyapatite/chitosan composites as potential drug delivery platforms for the sustained release of antibiotics in the treatment of osteomyelitis. J Pharm Sci. 2014 Feb; 103(2):567-79.
        View in: PubMed PMC4045008
      8. Kam KR, Desai TA. Nano- and microfabrication for overcoming drug delivery challenges. J Mater Chem B Mater Biol Med. 2013; 1(14):1878-1884.
        View in: PubMed
      9. Desai T. In the spotlight: Tissue engineering. IEEE Rev Biomed Eng. 2013; 6:27-8.
        View in: PubMed
      10. Desai TA. In the spotlight: tissue engineering. IEEE Rev Biomed Eng. 2010; 3:23-4.
        View in: PubMed
      11. Bernards DA, Desai TA. Nanoscale porosity in polymer films: fabrication and therapeutic applications. Soft Matter. 2010 Jan 1; 6(8):1621-1631.
        View in: PubMed
      12. Desai TA. In the spotlight: tissue engineering--quantitative analysis of complex 3-D tissues. IEEE Rev Biomed Eng. 2009; 2:21-2.
        View in: PubMed
      13. Desai TA. In the Spotlight: Tissue and Molecular Engineering. IEEE Rev Biomed Eng. 2008; 1:21-2.
        View in: PubMed
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