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    Sam Pleasure, MD, PhD

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentNeurology
    Address675 Nelson Rising Lane
    San Francisco CA 94158
    Phone415-502-5683
    vCardDownload vCard

      Collapse Biography 
      Collapse Education and Training
      University of PennsylvaniaM.D.School of Medicine1993
      University of California, San FranciscoResidency School of Medicine

      Collapse ORNG Applications 
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      Collapse Global Health

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Cocas LA, Fernandez G, Barch M, Doll J, Zamora Diaz I, Pleasure SJ. Cell Type-Specific Circuit Mapping Reveals the Presynaptic Connectivity of Developing Cortical Circuits. J Neurosci. 2016 Mar 16; 36(11):3378-90. PMID: 26985044.
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      2. Choe Y, Pleasure SJ, Mira H. Control of Adult Neurogenesis by Short-Range Morphogenic-Signaling Molecules. Cold Spring Harb Perspect Biol. 2015; 8(3). PMID: 26637286.
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      3. Choe Y, Huynh T, Pleasure SJ. Epithelial cells supply Sonic Hedgehog to the perinatal dentate gyrus via transport by platelets. Elife. 2015; 4. PMID: 26457609.
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      4. Yabut OR, Fernandez G, Huynh T, Yoon K, Pleasure SJ. Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis. Cell Rep. 2015 Sep 29; 12(12):2021-34. PMID: 26387942.
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      5. Yabut O, Pleasure SJ, Yoon K. A Notch above Sonic Hedgehog. Dev Cell. 2015 May 26; 33(4):371-2. PMID: 26017768.
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      6. Choe Y, Huynh T, Pleasure SJ. Migration of Oligodendrocyte Progenitor Cells Is Controlled by Transforming Growth Factor ß Family Proteins during Corticogenesis. J Neurosci. 2014 Nov 5; 34(45):14973-83. PMID: 25378163; PMCID: PMC4220029 [Available on 05/05/15].
      7. Berberoglu MA, Dong Z, Li G, Zheng J, Trejo Martinez Ldel C, Peng J, Wagle M, Reichholf B, Petritsch C, Li H, Pleasure SJ, Guo S. Heterogeneously expressed fezf2 patterns gradient Notch activity in balancing the quiescence, proliferation, and differentiation of adult neural stem cells. J Neurosci. 2014 Oct 15; 34(42):13911-23. PMID: 25319688; PMCID: PMC4198537 [Available on 04/15/15].
      8. Orosco LA, Ross AP, Cates SL, Scott SE, Wu D, Sohn J, Pleasure D, Pleasure SJ, Adamopoulos IE, Zarbalis KS. Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology. Nat Commun. 2014; 5:4692. PMID: 25198012; PMCID: PMC4159772 [Available on 03/08/15].
      9. Cocas L, Pleasure SJ. Wrong place, wrong time: ectopic progenitors cause cortical heterotopias. Nat Neurosci. 2014 Jul; 17(7):894-5. PMID: 24964156.
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      10. Yabut O, Pleasure SJ. The quintessence of quiescence. Neuron. 2014 May 7; 82(3):501-3. PMID: 24811373.
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      11. Choe Y, Zarbalis KS, Pleasure SJ. Neural crest-derived mesenchymal cells require Wnt signaling for their development and drive invagination of the telencephalic midline. PLoS One. 2014; 9(2):e86025. PMID: 24516524; PMCID: PMC3916303.
      12. Li G, Pleasure SJ. The development of hippocampal cellular assemblies. Wiley Interdiscip Rev Dev Biol. 2014 Mar-Apr; 3(2):165-77. PMID: 24719288.
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      13. Yang S, Edman LC, Sánchez-Alcañiz JA, Fritz N, Bonilla S, Hecht J, Uhlén P, Pleasure SJ, Villaescusa JC, Marín O, Arenas E. Cxcl12/Cxcr4 signaling controls the migration and process orientation of A9-A10 dopaminergic neurons. Development. 2013 Nov; 140(22):4554-64. PMID: 24154522.
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      14. Berger JR, Choi D, Kaminski HJ, Gordon MF, Hurko O, D'Cruz O, Pleasure SJ, Feldman EL. Importance and hurdles to drug discovery for neurological disease. Ann Neurol. 2013 Sep; 74(3):441-6. PMID: 25813523.
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      15. Ross AP, Mansilla MA, Choe Y, Helminski S, Sturm R, Maute RL, May SR, Hozyasz KK, Wójcicki P, Mostowska A, Davidson B, Adamopoulos IE, Pleasure SJ, Murray JC, Zarbalis KS. A mutation in mouse Pak1ip1 causes orofacial clefting while human PAK1IP1 maps to 6p24 translocation breaking points associated with orofacial clefting. PLoS One. 2013; 8(7):e69333. PMID: 23935987; PMCID: PMC3723895.
      16. Siegenthaler JA, Choe Y, Patterson KP, Hsieh I, Li D, Jaminet SC, Daneman R, Kume T, Huang EJ, Pleasure SJ. Foxc1 is required by pericytes during fetal brain angiogenesis. Biol Open. 2013 Jul 15; 2(7):647-59. PMID: 23862012; PMCID: PMC3711032.
      17. Li G, Fang L, Fernández G, Pleasure SJ. The ventral hippocampus is the embryonic origin for adult neural stem cells in the dentate gyrus. Neuron. 2013 May 22; 78(4):658-72. PMID: 23643936; PMCID: PMC3669230.
      18. Choe Y, Kozlova A, Graf D, Pleasure SJ. Bone morphogenic protein signaling is a major determinant of dentate development. J Neurosci. 2013 Apr 17; 33(16):6766-75. PMID: 23595735; PMCID: PMC3684166.
      19. Harrison-Uy SJ, Siegenthaler JA, Faedo A, Rubenstein JL, Pleasure SJ. CoupTFI interacts with retinoic acid signaling during cortical development. PLoS One. 2013; 8(3):e58219. PMID: 23472160; PMCID: PMC3589372.
      20. Huilgol D, Udin S, Shimogori T, Saha B, Roy A, Aizawa S, Hevner RF, Meyer G, Ohshima T, Pleasure SJ, Zhao Y, Tole S. Dual origins of the mammalian accessory olfactory bulb revealed by an evolutionarily conserved migratory stream. Nat Neurosci. 2013 Feb; 16(2):157-65. PMID: 23292680.
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      21. Choe Y, Pleasure SJ. Wnt signaling regulates intermediate precursor production in the postnatal dentate gyrus by regulating CXCR4 expression. Dev Neurosci. 2012; 34(6):502-14. PMID: 23257686.
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      22. Choe Y, Pleasure SJ. The GAP between axon pruning and repulsion. Dev Cell. 2012 Jul 17; 23(1):3-4. PMID: 22814595; PMCID: PMC3703152.
      23. Harrison-Uy SJ, Pleasure SJ. Wnt signaling and forebrain development. Cold Spring Harb Perspect Biol. 2012 Jul; 4(7):a008094. PMID: 22621768; PMCID: PMC3385962.
      24. Ultanir SK, Hertz NT, Li G, Ge WP, Burlingame AL, Pleasure SJ, Shokat KM, Jan LY, Jan YN. Chemical genetic identification of NDR1/2 kinase substrates AAK1 and Rabin8 Uncovers their roles in dendrite arborization and spine development. Neuron. 2012 Mar 22; 73(6):1127-42. PMID: 22445341; PMCID: PMC3333840.
      25. Choe Y, Siegenthaler JA, Pleasure SJ. A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation. Neuron. 2012 Feb 23; 73(4):698-712. PMID: 22365545; PMCID: PMC3292762.
      26. Jung HJ, Coffinier C, Choe Y, Beigneux AP, Davies BS, Yang SH, Barnes RH, Hong J, Sun T, Pleasure SJ, Young SG, Fong LG. Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA. Proc Natl Acad Sci U S A. 2012 Feb 14; 109(7):E423-31. PMID: 22308344; PMCID: PMC3289373.
      27. Zarbalis K, Choe Y, Siegenthaler JA, Orosco LA, Pleasure SJ. Meningeal defects alter the tangential migration of cortical interneurons in Foxc1hith/hith mice. Neural Dev. 2012; 7:2. PMID: 22248045; PMCID: PMC3287125.
      28. Gu X, Liu B, Wu X, Yan Y, Zhang Y, Wei Y, Pleasure SJ, Zhao C. Inducible genetic lineage tracing of cortical hem derived Cajal-Retzius cells reveals novel properties. PLoS One. 2011; 6(12):e28653. PMID: 22174859; PMCID: PMC3236758.
      29. Li Y, Tian C, Yang Y, Yan Y, Ni Y, Wei Y, Pleasure SJ, Zhao C. An inducible transgenic Cre mouse line for the study of hippocampal development and adult neurogenesis. Genesis. 2011 Dec; 49(12):919-26. PMID: 21538809.
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      30. Jiang L, Shen F, Degos V, Schonemann M, Pleasure SJ, Mellon SH, Young WL, Su H. Oligogenesis and oligodendrocyte progenitor maturation vary in different brain regions and partially correlate with local angiogenesis after ischemic stroke. Transl Stroke Res. 2011 Sep; 2(3):366-75. PMID: 22022343; PMCID: PMC3196661.
      31. Pino D, Choe Y, Pleasure SJ. Wnt5a controls neurite development in olfactory bulb interneurons. ASN Neuro. 2011; 3(3):e00059. PMID: 21539518; PMCID: PMC3155196.
      32. Li G, Pleasure SJ. Exciting information for inhibitory neurons. Neuron. 2011 Feb 24; 69(4):585-7. PMID: 21338869.
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      33. Munji RN, Choe Y, Li G, Siegenthaler JA, Pleasure SJ. Wnt signaling regulates neuronal differentiation of cortical intermediate progenitors. J Neurosci. 2011 Feb 2; 31(5):1676-87. PMID: 21289176; PMCID: PMC3040956.
      34. Siegenthaler JA, Pleasure SJ. We have got you 'covered': how the meninges control brain development. Curr Opin Genet Dev. 2011 Jun; 21(3):249-55. PMID: 21251809; PMCID: PMC3105186.
      35. Wang Y, Li G, Stanco A, Long JE, Crawford D, Potter GB, Pleasure SJ, Behrens T, Rubenstein JL. CXCR4 and CXCR7 have distinct functions in regulating interneuron migration. Neuron. 2011 Jan 13; 69(1):61-76. PMID: 21220099; PMCID: PMC3025760.
      36. Pozniak CD, Langseth AJ, Dijkgraaf GJ, Choe Y, Werb Z, Pleasure SJ. Sox10 directs neural stem cells toward the oligodendrocyte lineage by decreasing Suppressor of Fused expression. Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50):21795-800. PMID: 21098272; PMCID: PMC3003047.
      37. Langseth AJ, Munji RN, Choe Y, Huynh T, Pozniak CD, Pleasure SJ. Wnts influence the timing and efficiency of oligodendrocyte precursor cell generation in the telencephalon. J Neurosci. 2010 Oct 6; 30(40):13367-72. PMID: 20926663; PMCID: PMC2954511.
      38. Hecht JH, Siegenthaler JA, Patterson KP, Pleasure SJ. Primary cellular meningeal defects cause neocortical dysplasia and dyslamination. Ann Neurol. 2010 Oct; 68(4):454-64. PMID: 20976766; PMCID: PMC2966036.
      39. Siegenthaler JA, Pleasure SJ. There's no place like home for a neural stem cell. Cell Stem Cell. 2010 Aug 6; 7(2):141-3. PMID: 20682440.
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      40. Zhou W, Zhang Y, Li Y, Wei YS, Liu G, Liu DP, Pleasure SJ, Xie W, Zhao C. A transgenic Cre mouse line for the study of cortical and hippocampal development. Genesis. 2010 May; 48(5):343-50. PMID: 20143346.
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      41. Li G, Pleasure SJ. Ongoing interplay between the neural network and neurogenesis in the adult hippocampus. Curr Opin Neurobiol. 2010 Feb; 20(1):126-33. PMID: 20079627; PMCID: PMC2837845.
      42. Siegenthaler JA, Ashique AM, Zarbalis K, Patterson KP, Hecht JH, Kane MA, Folias AE, Choe Y, May SR, Kume T, Napoli JL, Peterson AS, Pleasure SJ. Retinoic acid from the meninges regulates cortical neuron generation. Cell. 2009 Oct 30; 139(3):597-609. PMID: 19879845; PMCID: PMC2772834.
      43. Freese JL, Pino D, Pleasure SJ. Wnt signaling in development and disease. Neurobiol Dis. 2010 May; 38(2):148-53. PMID: 19765659; PMCID: PMC2854277.
      44. Sall JW, Stratmann G, Leong J, McKleroy W, Mason D, Shenoy S, Pleasure SJ, Bickler PE. Isoflurane inhibits growth but does not cause cell death in hippocampal neural precursor cells grown in culture. Anesthesiology. 2009 Apr; 110(4):826-33. PMID: 19293697; PMCID: PMC2747751.
      45. Hoch RV, Rubenstein JL, Pleasure S. Genes and signaling events that establish regional patterning of the mammalian forebrain. Semin Cell Dev Biol. 2009 Jun; 20(4):378-86. PMID: 19560042.
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      46. Gu X, Yan Y, Li H, He D, Pleasure SJ, Zhao C. Characterization of the Frizzled10-CreER transgenic mouse: an inducible Cre line for the study of Cajal-Retzius cell development. Genesis. 2009 Mar; 47(3):210-6. PMID: 19241378; PMCID: PMC2698876.
      47. Li G, Kataoka H, Coughlin SR, Pleasure SJ. Identification of a transient subpial neurogenic zone in the developing dentate gyrus and its regulation by Cxcl12 and reelin signaling. Development. 2009 Jan; 136(2):327-35. PMID: 19103804; PMCID: PMC2685973.
      48. Zhou CJ, Molotkov A, Song L, Li Y, Pleasure DE, Pleasure SJ, Wang YZ. Ocular coloboma and dorsoventral neuroretinal patterning defects in Lrp6 mutant eyes. Dev Dyn. 2008 Dec; 237(12):3681-9. PMID: 18985738; PMCID: PMC2727282.
      49. Gu X, He D, Li Y, Hu C, Wei YS, Liu G, Liu D, Pleasure SJ, Xie W, Zhao C. Generation of Frizzled10-Cre transgenic mouse line: a useful tool for the study of dorsal telencephalic development. Genesis. 2008 Oct; 46(10):523-9. PMID: 18802960; PMCID: PMC2726759.
      50. Adesnik H, Li G, During MJ, Pleasure SJ, Nicoll RA. NMDA receptors inhibit synapse unsilencing during brain development. Proc Natl Acad Sci U S A. 2008 Apr 8; 105(14):5597-602. PMID: 18375768; PMCID: PMC2291097.
      51. Pleasure SJ, Guerrini R. Hypothalamic hamartomas and hedgehogs: not a laughing matter. Neurology. 2008 Feb 19; 70(8):588-9. PMID: 18285533.
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      52. Li G, Adesnik H, Li J, Long J, Nicoll RA, Rubenstein JL, Pleasure SJ. Regional distribution of cortical interneurons and development of inhibitory tone are regulated by Cxcl12/Cxcr4 signaling. J Neurosci. 2008 Jan 30; 28(5):1085-98. PMID: 18234887; PMCID: PMC3072297.
      53. Faedo A, Tomassy GS, Ruan Y, Teichmann H, Krauss S, Pleasure SJ, Tsai SY, Tsai MJ, Studer M, Rubenstein JL. COUP-TFI coordinates cortical patterning, neurogenesis, and laminar fate and modulates MAPK/ERK, AKT, and beta-catenin signaling. Cereb Cortex. 2008 Sep; 18(9):2117-31. PMID: 18165280; PMCID: PMC2733307.
      54. Li G, Berger O, Han SM, Paredes M, Wu NC, Pleasure SJ. Hilar mossy cells share developmental influences with dentate granule neurons. Dev Neurosci. 2008; 30(4):255-61. PMID: 17960053.
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      55. Zarbalis K, Siegenthaler JA, Choe Y, May SR, Peterson AS, Pleasure SJ. Cortical dysplasia and skull defects in mice with a Foxc1 allele reveal the role of meningeal differentiation in regulating cortical development. Proc Natl Acad Sci U S A. 2007 Aug 28; 104(35):14002-7. PMID: 17715063; PMCID: PMC1955817.
      56. Berger O, Li G, Han SM, Paredes M, Pleasure SJ. Expression of SDF-1 and CXCR4 during reorganization of the postnatal dentate gyrus. Dev Neurosci. 2007; 29(1-2):48-58. PMID: 17148948.
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      57. Grandgirard D, Bifrare YD, Pleasure SJ, Kummer J, Leib SL, Tauber MG. Pneumococcal meningitis induces apoptosis in recently postmitotic immature neurons in the dentate gyrus of neonatal rats. Dev Neurosci. 2007; 29(1-2):134-42. PMID: 17148956.
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      58. Li G, Pleasure SJ. Genetic regulation of dentate gyrus morphogenesis. Prog Brain Res. 2007; 163:143-52. PMID: 17765716.
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      59. Paredes MF, Li G, Berger O, Baraban SC, Pleasure SJ. Stromal-derived factor-1 (CXCL12) regulates laminar position of Cajal-Retzius cells in normal and dysplastic brains. J Neurosci. 2006 Sep 13; 26(37):9404-12. PMID: 16971524; PMCID: PMC2133346.
      60. Zhou CJ, Borello U, Rubenstein JL, Pleasure SJ. Neuronal production and precursor proliferation defects in the neocortex of mice with loss of function in the canonical Wnt signaling pathway. Neuroscience. 2006 Nov 3; 142(4):1119-31. PMID: 16920270.
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      61. Pozniak CD, Pleasure SJ. Genetic control of hippocampal neurogenesis. Genome Biol. 2006; 7(3):207. PMID: 16584531; PMCID: PMC1557761.
      62. Paredes M, Pleasure SJ, Baraban SC. Embryonic and early postnatal abnormalities contributing to the development of hippocampal malformations in a rodent model of dysplasia. J Comp Neurol. 2006 Mar 1; 495(1):133-48. PMID: 16432901; PMCID: PMC2827607.
      63. Zhao C, Guan W, Pleasure SJ. A transgenic marker mouse line labels Cajal-Retzius cells from the cortical hem and thalamocortical axons. Brain Res. 2006 Mar 10; 1077(1):48-53. PMID: 16490185.
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      64. Pozniak CD, Pleasure SJ. A tale of two signals: Wnt and Hedgehog in dentate neurogenesis. Sci STKE. 2006 Jan 24; 2006(319):pe5. PMID: 16434726.
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      65. Parent JM, Elliott RC, Pleasure SJ, Barbaro NM, Lowenstein DH. Aberrant seizure-induced neurogenesis in experimental temporal lobe epilepsy. Ann Neurol. 2006 Jan; 59(1):81-91. PMID: 16261566.
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      66. Zhao C, Avilés C, Abel RA, Almli CR, McQuillen P, Pleasure SJ. Hippocampal and visuospatial learning defects in mice with a deletion of frizzled 9, a gene in the Williams syndrome deletion interval. Development. 2005 Jun; 132(12):2917-27. PMID: 15930120.
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      67. Zhao C, Pleasure SJ. Frizzled9 protein is regionally expressed in the developing medial cortical wall and the cells derived from this region. Brain Res Dev Brain Res. 2005 Jun 9; 157(1):93-7. PMID: 15939089.
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      68. Li G, Pleasure SJ. Morphogenesis of the dentate gyrus: what we are learning from mouse mutants. Dev Neurosci. 2005 Mar-Aug; 27(2-4):93-9. PMID: 16046842.
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      69. Del Turco D, Gebhardt C, Burbach GJ, Pleasure SJ, Lowenstein DH, Deller T. Laminar organization of the mouse dentate gyrus: insights from BETA2/Neuro D mutant mice. J Comp Neurol. 2004 Sep 6; 477(1):81-95. PMID: 15281081.
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      70. Zhou CJ, Pinson KI, Pleasure SJ. Severe defects in dorsal thalamic development in low-density lipoprotein receptor-related protein-6 mutants. J Neurosci. 2004 Sep 1; 24(35):7632-9. PMID: 15342729.
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      71. Zhao C, Pleasure SJ. Frizzled-9 promoter drives expression of transgenes in the medial wall of the cortex and its chief derivative the hippocampus. Genesis. 2004 Sep; 40(1):32-9. PMID: 15354291.
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      72. Zhou CJ, Zhao C, Pleasure SJ. Wnt signaling mutants have decreased dentate granule cell production and radial glial scaffolding abnormalities. J Neurosci. 2004 Jan 7; 24(1):121-6. PMID: 14715945.
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      73. Kim AS, Pleasure SJ. Expression of the BMP antagonist Dan during murine forebrain development. Brain Res Dev Brain Res. 2003 Oct 10; 145(1):159-62. PMID: 14519502.
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      74. Bagri A, Cheng HJ, Yaron A, Pleasure SJ, Tessier-Lavigne M. Stereotyped pruning of long hippocampal axon branches triggered by retraction inducers of the semaphorin family. Cell. 2003 May 2; 113(3):285-99. PMID: 12732138.
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      75. Zhou CJ, Inagaki N, Pleasure SJ, Zhao LX, Kikuyama S, Shioda S. ATP-binding cassette transporter ABCA2 (ABC2) expression in the developing spinal cord and PNS during myelination. J Comp Neurol. 2002 Sep 30; 451(4):334-45. PMID: 12210128.
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      76. Bagri A, Gurney T, He X, Zou YR, Littman DR, Tessier-Lavigne M, Pleasure SJ. The chemokine SDF1 regulates migration of dentate granule cells. Development. 2002 Sep; 129(18):4249-60. PMID: 12183377.
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      77. Zhou CJ, Shioda S, Yada T, Inagaki N, Pleasure SJ, Kikuyama S. PACAP and its receptors exert pleiotropic effects in the nervous system by activating multiple signaling pathways. Curr Protein Pept Sci. 2002 Aug; 3(4):423-39. PMID: 12370005.
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      78. Bagri A, Marín O, Plump AS, Mak J, Pleasure SJ, Rubenstein JL, Tessier-Lavigne M. Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain. Neuron. 2002 Jan 17; 33(2):233-48. PMID: 11804571.
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      79. Castro PA, Pleasure SJ, Baraban SC. Hippocampal heterotopia with molecular and electrophysiological properties of neocortical neurons. Neuroscience. 2002; 114(4):961-72. PMID: 12379251.
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      80. Cheng HJ, Bagri A, Yaron A, Stein E, Pleasure SJ, Tessier-Lavigne M. Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections. Neuron. 2001 Oct 25; 32(2):249-63. PMID: 11683995.
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      81. Kim AS, Lowenstein DH, Pleasure SJ. Wnt receptors and Wnt inhibitors are expressed in gradients in the developing telencephalon. Mech Dev. 2001 May; 103(1-2):167-72. PMID: 11335128.
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      82. Kim AS, Anderson SA, Rubenstein JL, Lowenstein DH, Pleasure SJ. Pax-6 regulates expression of SFRP-2 and Wnt-7b in the developing CNS. J Neurosci. 2001 Mar 1; 21(5):RC132. PMID: 11222670.
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      83. Pleasure SJ. An arrow hits the Wnt signaling pathway. Trends Neurosci. 2001 Feb; 24(2):69-71. PMID: 11164924.
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      84. Elliott RC, Khademi S, Pleasure SJ, Parent JM, Lowenstein DH. Differential regulation of basic helix-loop-helix mRNAs in the dentate gyrus following status epilepticus. Neuroscience. 2001; 106(1):79-88. PMID: 11564418.
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      85. Pleasure SJ, Anderson S, Hevner R, Bagri A, Marin O, Lowenstein DH, Rubenstein JL. Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons. Neuron. 2000 Dec; 28(3):727-40. PMID: 11163262.
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      86. Pleasure SJ, Fischbein NJ. Correlation of clinical and neuroimaging findings in a case of rabies encephalitis. Arch Neurol. 2000 Dec; 57(12):1765-9. PMID: 11115243.
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      87. Pleasure SJ, Collins AE, Lowenstein DH. Unique expression patterns of cell fate molecules delineate sequential stages of dentate gyrus development. J Neurosci. 2000 Aug 15; 20(16):6095-105. PMID: 10934259.
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      88. Liu M, Pleasure SJ, Collins AE, Noebels JL, Naya FJ, Tsai MJ, Lowenstein DH. Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy. Proc Natl Acad Sci U S A. 2000 Jan 18; 97(2):865-70. PMID: 10639171; PMCID: PMC15422.
      89. Chen H, Bagri A, Zupicich JA, Zou Y, Stoeckli E, Pleasure SJ, Lowenstein DH, Skarnes WC, Chédotal A, Tessier-Lavigne M. Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections. Neuron. 2000 Jan; 25(1):43-56. PMID: 10707971.
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      90. Pleasure SJ, Fishman RA. Ventricular volume and transmural pressure gradient in normal pressure hydrocephalus. Arch Neurol. 1999 Oct; 56(10):1199-200. PMID: 10520934.
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      91. Pleasure SJ, Abosch A, Friedman J, Ko NU, Barbaro N, Dillon W, Fishman RA, Poncelet AN. Spontaneous intracranial hypotension resulting in stupor caused by diencephalic compression. Neurology. 1998 Jun; 50(6):1854-7. PMID: 9633740.
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      92. Merrick SE, Pleasure SJ, Lurie DI, Pijak DS, Selzer ME, Lee VM. Glial cells of the lamprey nervous system contain keratin-like proteins. J Comp Neurol. 1995 May 1; 355(2):199-210. PMID: 7541809.
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      93. Wertkin AM, Turner RS, Pleasure SJ, Golde TE, Younkin SG, Trojanowski JQ, Lee VM. Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides. Proc Natl Acad Sci U S A. 1993 Oct 15; 90(20):9513-7. PMID: 8415732; PMCID: PMC47599.
      94. Pleasure SJ, Lee VM. NTera 2 cells: a human cell line which displays characteristics expected of a human committed neuronal progenitor cell. J Neurosci Res. 1993 Aug 15; 35(6):585-602. PMID: 8411264.
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      95. Younkin DP, Tang CM, Hardy M, Reddy UR, Shi QY, Pleasure SJ, Lee VM, Pleasure D. Inducible expression of neuronal glutamate receptor channels in the NT2 human cell line. Proc Natl Acad Sci U S A. 1993 Mar 15; 90(6):2174-8. PMID: 7681588; PMCID: PMC46048.
      96. Pleasure SJ, Page C, Lee VM. Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons. J Neurosci. 1992 May; 12(5):1802-15. PMID: 1578271.
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      97. He XM, Wikstrand CJ, Friedman HS, Bigner SH, Pleasure S, Trojanowski JQ, Bigner DD. Differentiation characteristics of newly established medulloblastoma cell lines (D384 Med, D425 Med, and D458 Med) and their transplantable xenografts. Lab Invest. 1991 Jun; 64(6):833-43. PMID: 1904513.
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      98. Reddy UR, Pleasure S, Baker D, Lee VM, Ross AH, Pleasure D. Primitive neuroectodermal tumors (PNETs) of the CNS and PNS that express functional nerve growth factor receptors (NGFR) but fail to differentiate in response to NGF. Prog Clin Biol Res. 1991; 366:243-8. PMID: 1648743.
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      99. Pleasure SJ, Reddy UR, Venkatakrishnan G, Roy AK, Chen J, Ross AH, Trojanowski JQ, Pleasure DE, Lee VM. Introduction of nerve growth factor (NGF) receptors into a medulloblastoma cell line results in expression of high- and low-affinity NGF receptors but not NGF-mediated differentiation. Proc Natl Acad Sci U S A. 1990 Nov; 87(21):8496-500. PMID: 2172988; PMCID: PMC54983.
      100. Baker DL, Reddy UR, Pleasure S, Hardy M, Williams M, Tartaglione M, Biegel JA, Emanuel BS, Lo Presti P, Kreider B. Human central nervous system primitive neuroectodermal tumor expressing nerve growth factor receptors: CHP707m. Ann Neurol. 1990 Aug; 28(2):136-45. PMID: 2171417.
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