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    Kristine Yaffe, MD

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentPsychiatry
    AddressVAMC Box 181
    Phone415-221-4810x3985

       Overview 
       Overview
      Kristine Yaffe, MD is Professor in the Departments of Psychiatry, Neurology and Epidemiology at the University of California, San Francisco (UCSF) and Associate Chair of Research for the Department of Psychiatry. She is also Chief of Geriatric Psychiatry and Director of the Memory Disorders Clinic at the San Francisco VA Medical Center. In both her research and in her clinical work, she has directed her efforts towards improving the care of patients with cognitive disorders and other geriatric neuropsychiatric conditions.

      Dr. Yaffe's research has focused on the predictors and outcomes of cognitive decline and dementia in older adults. She is particularly interested in identifying novel risk factors for cognitive impairment that may lead to strategies to prevent cognitive decline. Dr. Yaffe currently has funded studies investigating physical and intellectual activity, sleep disorders, chronic medical conditions including diabetes, obesity and chronic kidney disease, and depression. Another more recent focus of her work is conceptualization and characterization of Healthy Brain Aging. Her work has been published in numerous prestigious journals including the Lancet, JAMA, and The New England Journal of Medicine and she is currently funded by the NIH, DOD, State of California Public Health Department, the Alzheimer Association and other foundations.


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       Bibliographic 
       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Norton S, Matthews FE, Barnes DE, Yaffe K, Brayne C. Potential for primary prevention of Alzheimer's disease: an analysis of population-based data. Lancet Neurol. 2014 Aug; 13(8):788-94.
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      2. Yaffe K, Hoang TD, Byers AL, Barnes DE, Friedl KE. Lifestyle and health-related risk factors and risk of cognitive aging among older veterans. Alzheimers Dement. 2014 Jun; 10(3 Suppl):S111-21.
        View in: PubMed
      3. Byers AL, Yaffe K. Depression and dementias among military veterans. Alzheimers Dement. 2014 Jun; 10(3 Suppl):S166-73.
        View in: PubMed
      4. Meziab O, Kirby KA, Williams B, Yaffe K, Byers AL, Barnes DE. Prisoner of war status, posttraumatic stress disorder, and dementia in older veterans. Alzheimers Dement. 2014 Jun; 10(3 Suppl):S236-41.
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      5. Weiner MW, Veitch DP, Hayes J, Neylan T, Grafman J, Aisen PS, Petersen RC, Jack C, Jagust W, Trojanowski JQ, Shaw LM, Saykin AJ, Green RC, Harvey D, Toga AW, Friedl KE, Pacifico A, Sheline Y, Yaffe K, Mohlenoff B. Effects of traumatic brain injury and posttraumatic stress disorder on Alzheimer's disease in veterans, using the Alzheimer's Disease Neuroimaging Initiative. Alzheimers Dement. 2014 Jun; 10(3S):S226-S235.
        View in: PubMed
      6. Rosso AL, Olson Hunt MJ, Yang M, Brach JS, Harris TB, Newman AB, Satterfield S, Studenski SA, Yaffe K, Aizenstein HJ, Rosano C. Higher step length variability indicates lower gray matter integrity of selected regions in older adults. Gait Posture. 2014 May; 40(1):225-30.
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      7. Zhu N, Jacobs DR, Schreiner PJ, Yaffe K, Bryan N, Launer LJ, Whitmer RA, Sidney S, Demerath E, Thomas W, Bouchard C, He K, Reis J, Sternfeld B. Cardiorespiratory fitness and cognitive function in middle age: The CARDIA Study. Neurology. 2014 Apr 15; 82(15):1339-46.
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      8. Metti AL, Yaffe K, Boudreau RM, Ganguli M, Lopez OL, Stone KL, Cauley JA. Change in inflammatory markers and cognitive status in the oldest-old women from the study of osteoporotic fractures. J Am Geriatr Soc. 2014 Apr; 62(4):662-6.
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      9. Tartaglia MC, Hu B, Mehta K, Neuhaus J, Yaffe K, Miller BL, Boxer A. Demographic and Neuropsychiatric Factors Associated With Off-label Medication Use in Frontotemporal Dementia and Alzheimer's Disease. Alzheimer Dis Assoc Disord. 2014 Apr-Jun; 28(2):182-9.
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      10. Blackwell T, Yaffe K, Laffan A, Ancoli-Israel S, Redline S, Ensrud KE, Song Y, Stone KL. Associations of Objectively and Subjectively Measured Sleep Quality with Subsequent Cognitive Decline in Older Community-Dwelling Men: The MrOS Sleep Study. Sleep. 2014; 37(4):655-63.
        View in: PubMed
      11. Yaffe K, Vittinghoff E, Pletcher MJ, Hoang TD, Launer LJ, Whitmer R, Coker LH, Sidney S. Early adult to midlife cardiovascular risk factors and cognitive function. Circulation. 2014 Apr 15; 129(15):1560-7.
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      12. Nettiksimmons J, Simonsick EM, Harris T, Satterfield S, Rosano C, Yaffe K. The Associations between Serum Brain-Derived Neurotrophic Factor, Potential Confounders, and Cognitive Decline: A Longitudinal Study. PLoS One. 2014; 9(3):e91339.
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      13. Byers AL, Covinsky KE, Neylan TC, Yaffe K. Chronicity of Posttraumatic Stress Disorder and Risk of Disability in Older Persons. JAMA Psychiatry. 2014 Mar 19.
        View in: PubMed
      14. Chao LL, Yaffe K, Samuelson K, Neylan TC. Hippocampal volume is inversely related to PTSD duration. Psychiatry Res. 2014 Mar 19.
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      15. Wilson VK, Houston DK, Kilpatrick L, Lovato J, Yaffe K, Cauley JA, Harris TB, Simonsick EM, Ayonayon HN, Kritchevsky SB, Sink KM. Relationship between 25-hydroxyvitamin d and cognitive function in older adults: the health, aging and body composition study. J Am Geriatr Soc. 2014 Apr; 62(4):636-41.
        View in: PubMed
      16. Gardner RC, Yaffe K. Traumatic brain injury may increase risk of young onset dementia. Ann Neurol. 2014 Mar; 75(3):339-41.
        View in: PubMed
      17. James BD, Leurgans SE, Hebert LE, Scherr PA, Yaffe K, Bennett DA. Contribution of Alzheimer disease to mortality in the United States. Neurology. 2014 Mar 25; 82(12):1045-50.
        View in: PubMed
      18. Olson Hunt MJ, Weissfeld L, Boudreau RM, Aizenstein H, Newman AB, Simonsick EM, Van Domelen DR, Thomas F, Yaffe K, Rosano C. A variant of sparse partial least squares for variable selection and data exploration. Front Neuroinform. 2014; 8:18.
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      19. Pottala JV, Yaffe K, Robinson JG, Espeland MA, Wallace R, Harris WS. Higher RBC EPA + DHA corresponds with larger total brain and hippocampal volumes: WHIMS-MRI Study. Neurology. 2014 Feb 4; 82(5):435-42.
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      20. Yaffe K, Falvey C, Harris TB, Newman A, Satterfield S, Koster A, Ayonayon H, Simonsick E. Effect of socioeconomic disparities on incidence of dementia among biracial older adults: prospective study. BMJ. 2013; 347:f7051.
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      21. Koyama A, Steinman M, Ensrud K, Hillier TA, Yaffe K. Long-term Cognitive and Functional Effects of Potentially Inappropriate Medications in Older Women. J Gerontol A Biol Sci Med Sci. 2014 Apr; 69(4):423-9.
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      22. Larson EB, Yaffe K, Langa KM. New insights into the dementia epidemic. N Engl J Med. 2013 Dec 12; 369(24):2275-7.
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      23. Cohen BE, Neylan TC, Yaffe K, Samuelson KW, Li Y, Barnes DE. Posttraumatic stress disorder and cognitive function: findings from the mind your heart study. J Clin Psychiatry. 2013 Nov; 74(11):1063-70.
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      24. Nadkarni NK, Nunley KA, Aizenstein H, Harris TB, Yaffe K, Satterfield S, Newman AB, Rosano C. Association Between Cerebellar Gray Matter Volumes, Gait Speed, and Information-Processing Ability in Older Adults Enrolled in the Health ABC Study. J Gerontol A Biol Sci Med Sci. 2014 Aug; 69(8):996-1003.
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      25. Lee CG, Schwartz AV, Yaffe K, Hillier TA, Leblanc ES, Cawthon PM. Changes in physical performance in older women according to presence and treatment of diabetes mellitus. J Am Geriatr Soc. 2013 Nov; 61(11):1872-8.
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      26. Kaup AR, Simonsick EM, Harris TB, Satterfield S, Metti AL, Ayonayon HN, Rubin SM, Yaffe K. Older adults with limited literacy are at increased risk for likely dementia. J Gerontol A Biol Sci Med Sci. 2014 Jul; 69(7):900-6.
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      27. Zeki Al Hazzouri A, Haan MN, Deng Y, Neuhaus J, Yaffe K. Reduced heart rate variability is associated with worse cognitive performance in elderly mexican americans. Hypertension. 2014 Jan; 63(1):181-7.
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      28. Tranah GJ, Yokoyama JS, Katzman SM, Nalls MA, Newman AB, Harris TB, Cesari M, Manini TM, Schork NJ, Cummings SR, Liu Y, Yaffe K. Mitochondrial DNA sequence associations with dementia and amyloid-ß in elderly African Americans. Neurobiol Aging. 2014 Feb; 35(2):442.e1-8.
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      29. Bettcher BM, Walsh CM, Watson C, Miller JW, Green R, Patel N, Miller BL, Neuhaus J, Yaffe K, Kramer JH. Body mass and white matter integrity: the influence of vascular and inflammatory markers. PLoS One. 2013; 8(10):e77741.
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      30. Barry LC, Thorpe RJ, Penninx BW, Yaffe K, Wakefield D, Ayonayon HN, Satterfield S, Newman AB, Simonsick EM. Race-related Differences in Depression Onset and Recovery in Older Persons Over Time: The Health, Aging, and Body Composition Study. Am J Geriatr Psychiatry. 2014 Jul; 22(7):682-91.
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      31. Zeki Al Hazzouri A, Vittinghoff E, Byers A, Covinsky K, Blazer D, Diem S, Ensrud KE, Yaffe K. Long-term Cumulative Depressive Symptom Burden and Risk of Cognitive Decline and Dementia Among Very Old Women. J Gerontol A Biol Sci Med Sci. 2014 May; 69(5):595-601.
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      32. Reis JP, Launer LJ, Terry JG, Loria CM, Zeki Al Hazzouri A, Sidney S, Yaffe K, Jacobs DR, Whitlow CT, Zhu N, Carr JJ. Subclinical atherosclerotic calcification and cognitive functioning in middle-aged adults: the CARDIA study. Atherosclerosis. 2013 Nov; 231(1):72-7.
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      33. Chao SZ, Matthews BR, Yokoyama JS, Lai NB, Ong H, Tse M, Yuan RF, Lin A, Kramer J, Yaffe K, Kornak J, Miller BL, Rosen HJ. Depressive symptoms in chinese-american subjects with cognitive impairment. Am J Geriatr Psychiatry. 2014 Jul; 22(7):642-52.
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      34. Hong CH, Falvey C, Harris TB, Simonsick EM, Satterfield S, Ferrucci L, Metti AL, Patel KV, Yaffe K. Anemia and risk of dementia in older adults: findings from the Health ABC study. Neurology. 2013 Aug 6; 81(6):528-33.
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      35. Yaffe K, Falvey CM, Hamilton N, Harris TB, Simonsick EM, Strotmeyer ES, Shorr RI, Metti A, Schwartz AV. Association between hypoglycemia and dementia in a biracial cohort of older adults with diabetes mellitus. JAMA Intern Med. 2013 Jul 22; 173(14):1300-6.
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      36. Metti AL, Cauley JA, Ayonayon HN, Harris TB, Rosano C, Williamson JD, Yaffe K. The demographic and medical correlates of plasma aß40 and aß42. Alzheimer Dis Assoc Disord. 2013 Jul-Sep; 27(3):244-9.
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      37. Weiner MW, Friedl KE, Pacifico A, Chapman JC, Jaffee MS, Little DM, Manley GT, McKee A, Petersen RC, Pitman RK, Yaffe K, Zetterberg H, Obana R, Bain LJ, Carrillo MC. Military risk factors for Alzheimer's disease. Alzheimers Dement. 2013 Jul; 9(4):445-51.
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      38. Gardner RC, Valcour V, Yaffe K. Dementia in the oldest old: a multi-factorial and growing public health issue. Alzheimers Res Ther. 2013 Jul 1; 5(4):27.
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      39. Milaneschi Y, Cesari M, Simonsick EM, Vogelzangs N, Kanaya AM, Yaffe K, Patrignani P, Metti A, Kritchevsky SB, Pahor M, Ferrucci L, Penninx BW. Lipid peroxidation and depressed mood in community-dwelling older men and women. PLoS One. 2013; 8(6):e65406.
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      40. Zhang Y, Schuff N, Camacho M, Chao LL, Fletcher TP, Yaffe K, Woolley SC, Madison C, Rosen HJ, Miller BL, Weiner MW. MRI markers for mild cognitive impairment: comparisons between white matter integrity and gray matter volume measurements. PLoS One. 2013; 8(6):e66367.
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      41. Barnes DE, Santos-Modesitt W, Poelke G, Kramer AF, Castro C, Middleton LE, Yaffe K. The Mental Activity and eXercise (MAX) trial: a randomized controlled trial to enhance cognitive function in older adults. JAMA Intern Med. 2013 May 13; 173(9):797-804.
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      42. Covinsky KE, Cenzer IS, Yaffe K, O'Brien S, Blazer DG. Dysphoria and anhedonia as risk factors for disability or death in older persons: implications for the assessment of geriatric depression. Am J Geriatr Psychiatry. 2014 Jun; 22(6):606-13.
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      43. Geda YE, Schneider LS, Gitlin LN, Miller DS, Smith GS, Bell J, Evans J, Lee M, Porsteinsson A, Lanctôt KL, Rosenberg PB, Sultzer DL, Francis PT, Brodaty H, Padala PP, Onyike CU, Ortiz LA, Ancoli-Israel S, Bliwise DL, Martin JL, Vitiello MV, Yaffe K, Zee PC, Herrmann N, Sweet RA, Ballard C, Khin NA, Alfaro C, Murray PS, Schultz S, Lyketsos CG. Neuropsychiatric symptoms in Alzheimer's disease: past progress and anticipation of the future. Alzheimers Dement. 2013 Sep; 9(5):602-8.
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      44. Yaffe K, Hoang T. Nonpharmacologic treatment and prevention strategies for dementia. Continuum (Minneap Minn). 2013 Apr; 19(2 Dementia):372-81.
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      45. Maglione JE, Ancoli-Israel S, Peters KW, Paudel ML, Yaffe K, Ensrud KE, Tranah GJ, Stone KL. Depressive symptoms and circadian activity rhythm disturbances in community-dwelling older women. Am J Geriatr Psychiatry. 2014 Apr; 22(4):349-61.
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      46. Mayeda ER, Haan MN, Kanaya AM, Yaffe K, Neuhaus J. Type 2 diabetes and 10-year risk of dementia and cognitive impairment among older Mexican Americans. Diabetes Care. 2013 Sep; 36(9):2600-6.
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      47. Givens JL, Mezzacappa C, Heeren T, Yaffe K, Fredman L. Depressive symptoms among dementia caregivers: role of mediating factors. Am J Geriatr Psychiatry. 2014 May; 22(5):481-8.
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      48. Reis JP, Loria CM, Launer LJ, Sidney S, Liu K, Jacobs DR, Zhu N, Lloyd-Jones DM, He K, Yaffe K. Cardiovascular health through young adulthood and cognitive functioning in midlife. Ann Neurol. 2013 Feb; 73(2):170-9.
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      49. Lin FR, Yaffe K, Xia J, Xue QL, Harris TB, Purchase-Helzner E, Satterfield S, Ayonayon HN, Ferrucci L, Simonsick EM. Hearing loss and cognitive decline in older adults. JAMA Intern Med. 2013 Feb 25; 173(4):293-9.
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      50. Stewart R, Weyant RJ, Garcia ME, Harris T, Launer LJ, Satterfield S, Simonsick EM, Yaffe K, Newman AB. Adverse oral health and cognitive decline: the health, aging and body composition study. J Am Geriatr Soc. 2013 Feb; 61(2):177-84.
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      51. Koyama A, Steinman M, Ensrud K, Hillier TA, Yaffe K. Ten-year trajectory of potentially inappropriate medications in very old women: importance of cognitive status. J Am Geriatr Soc. 2013 Feb; 61(2):258-63.
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      52. Zeki Al Hazzouri A, Newman AB, Simonsick E, Sink KM, Sutton Tyrrell K, Watson N, Satterfield S, Harris T, Yaffe K. Pulse wave velocity and cognitive decline in elders: the Health, Aging, and Body Composition study. Stroke. 2013 Feb; 44(2):388-93.
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      53. Hek K, Demirkan A, Lahti J, Terracciano A, Teumer A, Cornelis MC, Amin N, Bakshis E, Baumert J, Ding J, Liu Y, Marciante K, Meirelles O, Nalls MA, Sun YV, Vogelzangs N, Yu L, Bandinelli S, Benjamin EJ, Bennett DA, Boomsma D, Cannas A, Coker LH, de Geus E, De Jager PL, Diez-Roux AV, Purcell S, Hu FB, Rimm EB, Hunter DJ, Jensen MK, Curhan G, Rice K, Penman AD, Rotter JI, Sotoodehnia N, Emeny R, Eriksson JG, Evans DA, Ferrucci L, Fornage M, Gudnason V, Hofman A, Illig T, Kardia S, Kelly-Hayes M, Koenen K, Kraft P, Kuningas M, Massaro JM, Melzer D, Mulas A, Mulder CL, Murray A, Oostra BA, Palotie A, Penninx B, Petersmann A, Pilling LC, Psaty B, Rawal R, Reiman EM, Schulz A, Shulman JM, Singleton AB, Smith AV, Sutin AR, Uitterlinden AG, Völzke H, Widen E, Yaffe K, Zonderman AB, Cucca F, Harris T, Ladwig KH, Llewellyn DJ, Räikkönen K, Tanaka T, van Duijn CM, Grabe HJ, Launer LJ, Lunetta KL, Mosley TH, Newman AB, Tiemeier H, Murabito J. A genome-wide association study of depressive symptoms. Biol Psychiatry. 2013 Apr 1; 73(7):667-78.
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      54. Yaffe K. Traumatic brain injury and neuropsychiatric outcomes. Lancet Neurol. 2012 Dec; 11(12):1020-1.
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      55. Spira AP, Rebok GW, Stone KL, Kramer JH, Yaffe K. Depressive symptoms in oldest-old women: risk of mild cognitive impairment and dementia. Am J Geriatr Psychiatry. 2012 Dec; 20(12):1006-15.
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      56. Yaffe K, Ackerson L, Hoang TD, Go AS, Maguire MG, Ying GS, Daniel E, Bazzano LA, Coleman M, Cohen DL, Kusek JW, Ojo A, Seliger S, Xie D, Grunwald JE. Retinopathy and cognitive impairment in adults with CKD. Am J Kidney Dis. 2013 Feb; 61(2):219-27.
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      57. Falvey CM, Rosano C, Simonsick EM, Harris T, Strotmeyer ES, Satterfield S, Yaffe K. Macro- and microstructural magnetic resonance imaging indices associated with diabetes among community-dwelling older adults. Diabetes Care. 2013 Mar; 36(3):677-82.
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      58. Byers AL, Vittinghoff E, Lui LY, Hoang T, Blazer DG, Covinsky KE, Ensrud KE, Cauley JA, Hillier TA, Fredman L, Yaffe K. Twenty-year depressive trajectories among older women. Arch Gen Psychiatry. 2012 Oct; 69(10):1073-9.
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      59. Koyama A, O'Brien J, Weuve J, Blacker D, Metti AL, Yaffe K. The role of peripheral inflammatory markers in dementia and Alzheimer's disease: a meta-analysis. J Gerontol A Biol Sci Med Sci. 2013 Apr; 68(4):433-40.
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      60. Yaffe K, Falvey C, Hamilton N, Schwartz AV, Simonsick EM, Satterfield S, Cauley JA, Rosano C, Launer LJ, Strotmeyer ES, Harris TB. Diabetes, glucose control, and 9-year cognitive decline among older adults without dementia. Arch Neurol. 2012 Sep; 69(9):1170-5.
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      61. Espeland MA, Bryan RN, Goveas JS, Robinson JG, Siddiqui MS, Liu S, Hogan PE, Casanova R, Coker LH, Yaffe K, Masaki K, Rossom R, Resnick SM. Influence of type 2 diabetes on brain volumes and changes in brain volumes: results from the Women's Health Initiative Magnetic Resonance Imaging studies. Diabetes Care. 2013 Jan; 36(1):90-7.
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      62. Zeki Al Hazzouri A, Stone KL, Haan MN, Yaffe K. Leptin, mild cognitive impairment, and dementia among elderly women. J Gerontol A Biol Sci Med Sci. 2013 Feb; 68(2):175-80.
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      63. Byers AL, Covinsky KE, Barnes DE, Yaffe K. Dysthymia and depression increase risk of dementia and mortality among older veterans. Am J Geriatr Psychiatry. 2012 Aug; 20(8):664-72.
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      64. Zeki Al Hazzouri A, Haan MN, Whitmer RA, Yaffe K, Neuhaus J. Central obesity, leptin and cognitive decline: the Sacramento Area Latino Study on Aging. Dement Geriatr Cogn Disord. 2012; 33(6):400-9.
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      65. Spira AP, Covinsky K, Rebok GW, Stone KL, Redline S, Yaffe K. Objectively measured sleep quality and nursing home placement in older women. J Am Geriatr Soc. 2012 Jul; 60(7):1237-43.
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      66. Spira AP, Covinsky K, Rebok GW, Punjabi NM, Stone KL, Hillier TA, Ensrud KE, Yaffe K. Poor sleep quality and functional decline in older women. J Am Geriatr Soc. 2012 Jun; 60(6):1092-8.
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      67. Leishear K, Boudreau RM, Studenski SA, Ferrucci L, Rosano C, de Rekeneire N, Houston DK, Kritchevsky SB, Schwartz AV, Vinik AI, Hogervorst E, Yaffe K, Harris TB, Newman AB, Strotmeyer ES. Relationship between vitamin B12 and sensory and motor peripheral nerve function in older adults. J Am Geriatr Soc. 2012 Jun; 60(6):1057-63.
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      68. Milaneschi Y, Simonsick EM, Vogelzangs N, Strotmeyer ES, Yaffe K, Harris TB, Tolea MI, Ferrucci L, Penninx BW. Leptin, abdominal obesity, and onset of depression in older men and women. J Clin Psychiatry. 2012 Sep; 73(9):1205-11.
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      69. Craft S, Foster TC, Landfield PW, Maier SF, Resnick SM, Yaffe K. Session III: Mechanisms of age-related cognitive change and targets for intervention: inflammatory, oxidative, and metabolic processes. J Gerontol A Biol Sci Med Sci. 2012 Jun; 67(7):754-9.
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      70. Barnes DE, Yaffe K, Byers AL, McCormick M, Schaefer C, Whitmer RA. Midlife vs late-life depressive symptoms and risk of dementia: differential effects for Alzheimer disease and vascular dementia. Arch Gen Psychiatry. 2012 May; 69(5):493-8.
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      71. Yaffe K, Tocco M, Petersen RC, Sigler C, Burns LC, Cornelius C, Khachaturian AS, Irizarry MC, Carrillo MC. The epidemiology of Alzheimer's disease: laying the foundation for drug design, conduct, and analysis of clinical trials. Alzheimers Dement. 2012 May; 8(3):237-42.
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      72. Rosano C, Aizenstein HJ, Newman AB, Venkatraman V, Harris T, Ding J, Satterfield S, Yaffe K. Neuroimaging differences between older adults with maintained versus declining cognition over a 10-year period. Neuroimage. 2012 Aug 1; 62(1):307-13.
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      73. Metti AL, Cauley JA, Newman AB, Ayonayon HN, Barry LC, Kuller LM, Satterfield S, Simonsick EM, Yaffe K. Plasma beta amyloid level and depression in older adults. J Gerontol A Biol Sci Med Sci. 2013 Jan; 68(1):74-9.
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      74. Fischer MJ, Xie D, Jordan N, Kop WJ, Krousel-Wood M, Kurella Tamura M, Kusek JW, Ford V, Rosen LK, Strauss L, Teal VL, Yaffe K, Powe NR, Lash JP. Factors associated with depressive symptoms and use of antidepressant medications among participants in the Chronic Renal Insufficiency Cohort (CRIC) and Hispanic-CRIC Studies. Am J Kidney Dis. 2012 Jul; 60(1):27-38.
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      75. Koyama A, Stone K, Yaffe K. Serum oxidized low-density lipoprotein level and risk of cognitive impairment in older women. Neurobiol Aging. 2013 Feb; 34(2):634-635.e2.
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      76. Slinin Y, Paudel M, Taylor BC, Ishani A, Rossom R, Yaffe K, Blackwell T, Lui LY, Hochberg M, Ensrud KE. Association between serum 25(OH) vitamin D and the risk of cognitive decline in older women. J Gerontol A Biol Sci Med Sci. 2012 Oct; 67(10):1092-8.
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      77. Maglione JE, Ancoli-Israel S, Peters KW, Paudel ML, Yaffe K, Ensrud KE, Stone KL. Depressive symptoms and subjective and objective sleep in community-dwelling older women. J Am Geriatr Soc. 2012 Apr; 60(4):635-43.
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      78. Haan M, Espeland MA, Klein BE, Casanova R, Gaussoin SA, Jackson RD, Millen AE, Resnick SM, Rossouw JE, Shumaker SA, Wallace R, Yaffe K. Cognitive function and retinal and ischemic brain changes: the Women's Health Initiative. Neurology. 2012 Mar 27; 78(13):942-9.
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      79. Rosano C, Bennett DA, Newman AB, Venkatraman V, Yaffe K, Harris T, Kritchevsky S, Aizenstein HJ. Patterns of focal gray matter atrophy are associated with bradykinesia and gait disturbances in older adults. J Gerontol A Biol Sci Med Sci. 2012 Sep; 67(9):957-62.
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      80. Fine EM, Kramer JH, Lui LY, Yaffe K. Normative data in women aged 85 and older: verbal fluency, digit span, and the CVLT-II short form. Clin Neuropsychol. 2012; 26(1):18-30.
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      81. Byers AL, Arean PA, Yaffe K. Low use of mental health services among older Americans with mood and anxiety disorders. Psychiatr Serv. 2012 Jan; 63(1):66-72.
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      82. Tranah GJ, Nalls MA, Katzman SM, Yokoyama JS, Lam ET, Zhao Y, Mooney S, Thomas F, Newman AB, Liu Y, Cummings SR, Harris TB, Yaffe K. Mitochondrial DNA sequence variation associated with dementia and cognitive function in the elderly. J Alzheimers Dis. 2012; 32(2):357-72.
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      83. Scott Mackin R, Lesselyong JA, Yaffe K. Pattern of cognitive impairment in older veterans with posttraumatic stress disorder evaluated at a memory disorders clinic. Int J Geriatr Psychiatry. 2012 Jun; 27(6):637-42.
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      84. Blackwell T, Yaffe K, Ancoli-Israel S, Redline S, Ensrud KE, Stefanick ML, Laffan A, Stone KL. Associations between sleep architecture and sleep-disordered breathing and cognition in older community-dwelling men: the Osteoporotic Fractures in Men Sleep Study. J Am Geriatr Soc. 2011 Dec; 59(12):2217-25.
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      85. Tranah GJ, Blackwell T, Stone KL, Ancoli-Israel S, Paudel ML, Ensrud KE, Cauley JA, Redline S, Hillier TA, Cummings SR, Yaffe K. Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older women. Ann Neurol. 2011 Nov; 70(5):722-32.
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      86. Weston A, Barton C, Lesselyong J, Yaffe K. Functional deficits among patients with mild cognitive impairment. Alzheimers Dement. 2011 Nov; 7(6):611-4.
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      87. Barton C, Morris R, Rothlind J, Yaffe K. Video-telemedicine in a memory disorders clinic: evaluation and management of rural elders with cognitive impairment. Telemed J E Health. 2011 Dec; 17(10):789-93.
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      88. Blackwell T, Yaffe K, Ancoli-Israel S, Redline S, Ensrud KE, Stefanick ML, Laffan A, Stone KL. Association of sleep characteristics and cognition in older community-dwelling men: the MrOS sleep study. Sleep. 2011 Oct; 34(10):1347-56.
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      89. Venkatraman VK, Aizenstein HJ, Newman AB, Yaffe K, Harris T, Kritchevsky S, Ayonayon HN, Rosano C. Lower Digit Symbol Substitution Score in the Oldest Old is Related to Magnetization Transfer and Diffusion Tensor Imaging of the White Matter. Front Aging Neurosci. 2011; 3:11.
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      90. Yaffe K, Lindquist K, Schwartz AV, Vitartas C, Vittinghoff E, Satterfield S, Simonsick EM, Launer L, Rosano C, Cauley JA, Harris T. Advanced glycation end product level, diabetes, and accelerated cognitive aging. Neurology. 2011 Oct 4; 77(14):1351-6.
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      122. Tranah GJ, Parimi N, Blackwell T, Ancoli-Israel S, Ensrud KE, Cauley JA, Redline S, Lane N, Paudel ML, Hillier TA, Yaffe K, Cummings SR, Stone KL. Postmenopausal hormones and sleep quality in the elderly: a population based study. BMC Womens Health. 2010; 10:15.
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      151. Fotuhi M, Mohassel P, Yaffe K. Fish consumption, long-chain omega-3 fatty acids and risk of cognitive decline or Alzheimer disease: a complex association. Nat Clin Pract Neurol. 2009 Mar; 5(3):140-52.
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      157. Cauley JA, Lui LY, Barnes D, Ensrud KE, Zmuda JM, Hillier TA, Hochberg MC, Schwartz AV, Yaffe K, Cummings SR, Newman AB. Successful skeletal aging: a marker of low fracture risk and longevity. The Study of Osteoporotic Fractures (SOF). J Bone Miner Res. 2009 Jan; 24(1):134-43.
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      159. Slinin Y, Paudel ML, Ishani A, Taylor BC, Yaffe K, Murray AM, Fink HA, Orwoll ES, Cummings SR, Barrett-Connor E, Jassal S, Ensrud KE. Kidney function and cognitive performance and decline in older men. J Am Geriatr Soc. 2008 Nov; 56(11):2082-8.
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      165. Teng E, Ringman JM, Ross LK, Mulnard RA, Dick MB, Bartzokis G, Davies HD, Galasko D, Hewett L, Mungas D, Reed BR, Schneider LS, Segal-Gidan F, Yaffe K, Cummings JL. Diagnosing depression in Alzheimer disease with the national institute of mental health provisional criteria. Am J Geriatr Psychiatry. 2008 Jun; 16(6):469-77.
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      169. Huang A, Yaffe K, Vittinghoff E, Kuppermann M, Addis I, Hanes V, Quan J, Grady D. The effect of ultralow-dose transdermal estradiol on sexual function in postmenopausal women. Am J Obstet Gynecol. 2008 Mar; 198(3):265.e1-7.
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      172. Mehta KM, Yaffe K, Pérez-Stable EJ, Stewart A, Barnes D, Kurland BF, Miller BL. Race/ethnic differences in AD survival in US Alzheimer's Disease Centers. Neurology. 2008 Apr 1; 70(14):1163-70.
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      182. Jeste DV, Blazer D, Casey D, Meeks T, Salzman C, Schneider L, Tariot P, Yaffe K. ACNP White Paper: update on use of antipsychotic drugs in elderly persons with dementia. Neuropsychopharmacology. 2008 Apr; 33(5):957-70.
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      185. Diem SJ, Blackwell TL, Stone KL, Yaffe K, Haney EM, Bliziotes MM, Ensrud KE. Use of antidepressants and rates of hip bone loss in older women: the study of osteoporotic fractures. Arch Intern Med. 2007 Jun 25; 167(12):1240-5.
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      193. Whitmer RA, Gunderson EP, Quesenberry CP, Zhou J, Yaffe K. Body mass index in midlife and risk of Alzheimer disease and vascular dementia. Curr Alzheimer Res. 2007 Apr; 4(2):103-9.
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      195. Brenes GA, Kritchevsky SB, Mehta KM, Yaffe K, Simonsick EM, Ayonayon HN, Rosano C, Rubin SM, Satterfield S, Penninx BW. Scared to death: results from the Health, Aging, and Body Composition study. Am J Geriatr Psychiatry. 2007 Mar; 15(3):262-5.
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      196. Barnes DE, Cauley JA, Lui LY, Fink HA, McCulloch C, Stone KL, Yaffe K. Women who maintain optimal cognitive function into old age. J Am Geriatr Soc. 2007 Feb; 55(2):259-64.
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      197. Mehta KM, Yaffe K, Brenes GA, Newman AB, Shorr RI, Simonsick EM, Ayonayon HN, Rubin SM, Covinsky KE. Anxiety symptoms and decline in physical function over 5 years in the health, aging and body composition study. J Am Geriatr Soc. 2007 Feb; 55(2):265-70.
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      198. Zhang Y, Schuff N, Jahng GH, Bayne W, Mori S, Schad L, Mueller S, Du AT, Kramer JH, Yaffe K, Chui H, Jagust WJ, Miller BL, Weiner MW. Diffusion tensor imaging of cingulum fibers in mild cognitive impairment and Alzheimer disease. Neurology. 2007 Jan 2; 68(1):13-9.
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      199. Barnes DE, Whitmer RA, Yaffe K. Physical activity and dementia: The need for prevention trials. Exerc Sport Sci Rev. 2007 Jan; 35(1):24-9.
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      200. Yaffe K, Barnes D, Lindquist K, Cauley J, Simonsick EM, Penninx B, Satterfield S, Harris T, Cummings SR. Endogenous sex hormone levels and risk of cognitive decline in an older biracial cohort. Neurobiol Aging. 2007 Feb; 28(2):171-8.
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      201. Yaffe K, Kanaya AM, Lindquist K, Hsueh WC, Cummings SR, Beamer B, Newman A, Rosano C, Li R, Harris T. PPAR-gamma Pro12Ala genotype and risk of cognitive decline in elders. Neurobiol Aging. 2008 Jan; 29(1):78-83.
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      202. Ensrud KE, Blackwell TL, Ancoli-Israel S, Redline S, Yaffe K, Diem S, Claman D, Stone KL. Use of selective serotonin reuptake inhibitors and sleep disturbances in community-dwelling older women. J Am Geriatr Soc. 2006 Oct; 54(10):1508-15.
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      203. Yaffe K, Petersen RC, Lindquist K, Kramer J, Miller B. Subtype of mild cognitive impairment and progression to dementia and death. Dement Geriatr Cogn Disord. 2006; 22(4):312-9.
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      204. Kramer JH, Nelson A, Johnson JK, Yaffe K, Glenn S, Rosen HJ, Miller BL. Multiple cognitive deficits in amnestic mild cognitive impairment. Dement Geriatr Cogn Disord. 2006; 22(4):306-11.
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      205. Elkins JS, Whitmer RA, Sidney S, Sorel M, Yaffe K, Johnston SC. Midlife obesity and long-term risk of nursing home admission. Obesity (Silver Spring). 2006 Aug; 14(8):1472-8.
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      206. Sudore RL, Yaffe K, Satterfield S, Harris TB, Mehta KM, Simonsick EM, Newman AB, Rosano C, Rooks R, Rubin SM, Ayonayon HN, Schillinger D. Limited literacy and mortality in the elderly: the health, aging, and body composition study. J Gen Intern Med. 2006 Aug; 21(8):806-12.
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      207. Yaffe K, Blackwell T, Whitmer RA, Krueger K, Barrett Connor E. Glycosylated hemoglobin level and development of mild cognitive impairment or dementia in older women. J Nutr Health Aging. 2006 Jul-Aug; 10(4):293-5.
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      208. Yaffe K, Vittinghoff E, Ensrud KE, Johnson KC, Diem S, Hanes V, Grady D. Effects of ultra-low-dose transdermal estradiol on cognition and health-related quality of life. Arch Neurol. 2006 Jul; 63(7):945-50.
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      209. Lyketsos CG, Colenda CC, Beck C, Blank K, Doraiswamy MP, Kalunian DA, Yaffe K. Position statement of the American Association for Geriatric Psychiatry regarding principles of care for patients with dementia resulting from Alzheimer disease. Am J Geriatr Psychiatry. 2006 Jul; 14(7):561-72.
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      210. Barton C, Yaffe K. Reducing neuroleptic use in long-term-care settings. Lancet Neurol. 2006 Jun; 5(6):469-70.
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      211. Yaffe K, Steffens D. Epidemiology of mental health: a keystone of geriatric psychiatry. Am J Geriatr Psychiatry. 2006 Jun; 14(6):477-9.
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      212. Hou CE, Yaffe K, Pérez-Stable EJ, Miller BL. Frequency of dementia etiologies in four ethnic groups. Dement Geriatr Cogn Disord. 2006; 22(1):42-7.
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      213. Sudore RL, Mehta KM, Simonsick EM, Harris TB, Newman AB, Satterfield S, Rosano C, Rooks RN, Rubin SM, Ayonayon HN, Yaffe K. Limited literacy in older people and disparities in health and healthcare access. J Am Geriatr Soc. 2006 May; 54(5):770-6.
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      214. Sink KM, Covinsky KE, Barnes DE, Newcomer RJ, Yaffe K. Caregiver characteristics are associated with neuropsychiatric symptoms of dementia. J Am Geriatr Soc. 2006 May; 54(5):796-803.
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      215. Pope SK, Kritchevsky SB, Ambrosone C, Yaffe K, Tylavsky F, Simonsick EM, Rosano C, Stewart S, Harris T. Myeloperoxidase polymorphism and cognitive decline in older adults in the Health, Aging, and Body Composition Study. Am J Epidemiol. 2006 Jun 15; 163(12):1084-90.
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      216. Zhu X, Schuff N, Kornak J, Soher B, Yaffe K, Kramer JH, Ezekiel F, Miller BL, Jagust WJ, Weiner MW. Effects of Alzheimer disease on fronto-parietal brain N-acetyl aspartate and myo-inositol using magnetic resonance spectroscopic imaging. Alzheimer Dis Assoc Disord. 2006 Apr-Jun; 20(2):77-85.
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      217. Blackwell T, Yaffe K, Ancoli-Israel S, Schneider JL, Cauley JA, Hillier TA, Fink HA, Stone KL. Poor sleep is associated with impaired cognitive function in older women: the study of osteoporotic fractures. J Gerontol A Biol Sci Med Sci. 2006 Apr; 61(4):405-10.
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      218. Barnes DE, Alexopoulos GS, Lopez OL, Williamson JD, Yaffe K. Depressive symptoms, vascular disease, and mild cognitive impairment: findings from the Cardiovascular Health Study. Arch Gen Psychiatry. 2006 Mar; 63(3):273-9.
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      219. Hendrie HC, Albert MS, Butters MA, Gao S, Knopman DS, Launer LJ, Yaffe K, Cuthbert BN, Edwards E, Wagster MV. The NIH Cognitive and Emotional Health Project. Report of the Critical Evaluation Study Committee. Alzheimers Dement. 2006 Jan; 2(1):12-32.
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      220. Lu PH, Masterman DA, Mulnard R, Cotman C, Miller B, Yaffe K, Reback E, Porter V, Swerdloff R, Cummings JL. Effects of testosterone on cognition and mood in male patients with mild Alzheimer disease and healthy elderly men. Arch Neurol. 2006 Feb; 63(2):177-85.
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      221. Newcomer RJ, Clay TH, Yaffe K, Covinsky KE. Mortality risk and prospective medicare expenditures for persons with dementia. J Am Geriatr Soc. 2005 Nov; 53(11):2001-6.
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      222. Yaffe K. Research and care of patients with dementia: moving beyond memory loss. Am J Geriatr Psychiatry. 2005 Nov; 13(11):921-5.
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      223. Barton C, Miller B, Yaffe K. Improved evaluation and management of cognitive impairment: results of a comprehensive intervention in long-term care. J Am Med Dir Assoc. 2006 Feb; 7(2):84-9.
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      224. Sands LP, Landefeld CS, Ayers SM, Yaffe K, Palmer R, Fortinsky R, Counsell SR, Covinsky KE. Disparities between black and white patients in functional improvement after hospitalization for an acute illness. J Am Geriatr Soc. 2005 Oct; 53(10):1811-6.
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      225. Roberson ED, Hesse JH, Rose KD, Slama H, Johnson JK, Yaffe K, Forman MS, Miller CA, Trojanowski JQ, Kramer JH, Miller BL. Frontotemporal dementia progresses to death faster than Alzheimer disease. Neurology. 2005 Sep 13; 65(5):719-25.
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      226. Barnes DE, Yaffe K. Vitamin E and donepezil for the treatment of mild cognitive impairment. N Engl J Med. 2005 Sep 1; 353(9):951-2; author reply 951-2.
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      227. Koster A, Penninx BW, Bosma H, Kempen GI, Newman AB, Rubin SM, Satterfield S, Atkinson HH, Ayonayon HN, Rosano C, Yaffe K, Harris TB, Rooks RN, Van Eijk JT, Kritchevsky SB. Socioeconomic differences in cognitive decline and the role of biomedical factors. Ann Epidemiol. 2005 Sep; 15(8):564-71.
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      228. Mehta KM, Yin M, Resendez C, Yaffe K. Ethnic differences in acetylcholinesterase inhibitor use for Alzheimer disease. Neurology. 2005 Jul 12; 65(1):159-62.
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      229. Elkins JS, Yaffe K, Cauley JA, Fink HA, Hillier TA, Johnston SC. Pre-existing hypertension and the impact of stroke on cognitive function. Ann Neurol. 2005 Jul; 58(1):68-74.
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      231. Kurella M, Chertow GM, Fried LF, Cummings SR, Harris T, Simonsick E, Satterfield S, Ayonayon H, Yaffe K. Chronic kidney disease and cognitive impairment in the elderly: the health, aging, and body composition study. J Am Soc Nephrol. 2005 Jul; 16(7):2127-33.
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      232. Whitmer RA, Gunderson EP, Barrett-Connor E, Quesenberry CP, Yaffe K. Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study. BMJ. 2005 Jun 11; 330(7504):1360.
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      233. Yaffe K, Krueger K, Cummings SR, Blackwell T, Henderson VW, Sarkar S, Ensrud K, Grady D. Effect of raloxifene on prevention of dementia and cognitive impairment in older women: the Multiple Outcomes of Raloxifene Evaluation (MORE) randomized trial. Am J Psychiatry. 2005 Apr; 162(4):683-90.
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      234. Sink KM, Holden KF, Yaffe K. Pharmacological treatment of neuropsychiatric symptoms of dementia: a review of the evidence. JAMA. 2005 Feb 2; 293(5):596-608.
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      235. Chao LL, Schuff N, Kramer JH, Du AT, Capizzano AA, O'Neill J, Wolkowitz OM, Jagust WJ, Chui HC, Miller BL, Yaffe K, Weiner MW. Reduced medial temporal lobe N-acetylaspartate in cognitively impaired but nondemented patients. Neurology. 2005 Jan 25; 64(2):282-9.
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      236. Otte C, Hart S, Neylan TC, Marmar CR, Yaffe K, Mohr DC. A meta-analysis of cortisol response to challenge in human aging: importance of gender. Psychoneuroendocrinology. 2005 Jan; 30(1):80-91.
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      237. Rosano C, Simonsick EM, Harris TB, Kritchevsky SB, Brach J, Visser M, Yaffe K, Newman AB. Association between physical and cognitive function in healthy elderly: the health, aging and body composition study. Neuroepidemiology. 2005; 24(1-2):8-14.
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      238. Kurella M, Yaffe K, Shlipak MG, Wenger NK, Chertow GM. Chronic kidney disease and cognitive impairment in menopausal women. Am J Kidney Dis. 2005 Jan; 45(1):66-76.
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      239. Kurella M, Luan J, Yaffe K, Chertow GM. Validation of the Kidney Disease Quality of Life (KDQOL) cognitive function subscale. Kidney Int. 2004 Dec; 66(6):2361-7.
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      240. Lin MY, Gutierrez PR, Stone KL, Yaffe K, Ensrud KE, Fink HA, Sarkisian CA, Coleman AL, Mangione CM. Vision impairment and combined vision and hearing impairment predict cognitive and functional decline in older women. J Am Geriatr Soc. 2004 Dec; 52(12):1996-2002.
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      241. Mehta KM, Simonsick EM, Rooks R, Newman AB, Pope SK, Rubin SM, Yaffe K. Black and white differences in cognitive function test scores: what explains the difference? J Am Geriatr Soc. 2004 Dec; 52(12):2120-7.
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      242. Yaffe K, Kanaya A, Lindquist K, Simonsick EM, Harris T, Shorr RI, Tylavsky FA, Newman AB. The metabolic syndrome, inflammation, and risk of cognitive decline. JAMA. 2004 Nov 10; 292(18):2237-42.
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      244. Kurella M, Chertow GM, Luan J, Yaffe K. Cognitive impairment in chronic kidney disease. J Am Geriatr Soc. 2004 Nov; 52(11):1863-9.
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      245. Modelska K, Litwack S, Ewing SK, Yaffe K. Endogenous estrogen levels affect sexual function in elderly post-menopausal women. Maturitas. 2004 Oct 15; 49(2):124-33.
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      246. Ezekiel F, Chao L, Kornak J, Du AT, Cardenas V, Truran D, Jagust W, Chui H, Miller B, Yaffe K, Schuff N, Weiner M. Comparisons between global and focal brain atrophy rates in normal aging and Alzheimer disease: Boundary Shift Integral versus tracing of the entorhinal cortex and hippocampus. Alzheimer Dis Assoc Disord. 2004 Oct-Dec; 18(4):196-201.
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      247. Yaffe K, Blackwell T, Kanaya AM, Davidowitz N, Barrett-Connor E, Krueger K. Diabetes, impaired fasting glucose, and development of cognitive impairment in older women. Neurology. 2004 Aug 24; 63(4):658-63.
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      248. Sink KM, Covinsky KE, Newcomer R, Yaffe K. Ethnic differences in the prevalence and pattern of dementia-related behaviors. J Am Geriatr Soc. 2004 Aug; 52(8):1277-83.
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      249. Kanaya AM, Barrett-Connor E, Gildengorin G, Yaffe K. Change in cognitive function by glucose tolerance status in older adults: a 4-year prospective study of the Rancho Bernardo study cohort. Arch Intern Med. 2004 Jun 28; 164(12):1327-33.
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      250. Edwards ER, Lindquist K, Yaffe K. Clinical profile and course of cognitively normal patients evaluated in memory disorders clinics. Neurology. 2004 May 11; 62(9):1639-42.
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      251. Kurella M, Ireland C, Hlatky MA, Shlipak MG, Yaffe K, Hulley SB, Chertow GM. Physical and sexual function in women with chronic kidney disease. Am J Kidney Dis. 2004 May; 43(5):868-76.
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      252. Sands LP, Ferreira P, Stewart AL, Brod M, Yaffe K. What explains differences between dementia patients' and their caregivers' ratings of patients' quality of life? Am J Geriatr Psychiatry. 2004 May-Jun; 12(3):272-80.
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      253. Yaffe K. Testosterone and the brain: uncharted territory. Lancet Neurol. 2004 May; 3(5):270.
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      254. Covinsky KE, Yaffe K. Dementia, prognosis, and the needs of patients and caregivers. Ann Intern Med. 2004 Apr 6; 140(7):573-4.
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      255. Barnes DE, Tager IB, Satariano WA, Yaffe K. The relationship between literacy and cognition in well-educated elders. J Gerontol A Biol Sci Med Sci. 2004 Apr; 59(4):390-5.
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      256. Brach JS, Simonsick EM, Kritchevsky S, Yaffe K, Newman AB. The association between physical function and lifestyle activity and exercise in the health, aging and body composition study. J Am Geriatr Soc. 2004 Apr; 52(4):502-9.
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      257. Du AT, Schuff N, Kramer JH, Ganzer S, Zhu XP, Jagust WJ, Miller BL, Reed BR, Mungas D, Yaffe K, Chui HC, Weiner MW. Higher atrophy rate of entorhinal cortex than hippocampus in AD. Neurology. 2004 Feb 10; 62(3):422-7.
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      258. Covinsky KE, Newcomer R, Fox P, Wood J, Sands L, Dane K, Yaffe K. Patient and caregiver characteristics associated with depression in caregivers of patients with dementia. J Gen Intern Med. 2003 Dec; 18(12):1006-14.
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      259. Yaffe K, Edwards ER, Lui LY, Zmuda JM, Ferrell RE, Cauley JA. Androgen receptor CAG repeat polymorphism is associated with cognitive function in older men. Biol Psychiatry. 2003 Nov 1; 54(9):943-6.
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      260. Penninx BW, Kritchevsky SB, Yaffe K, Newman AB, Simonsick EM, Rubin S, Ferrucci L, Harris T, Pahor M. Inflammatory markers and depressed mood in older persons: results from the Health, Aging and Body Composition study. Biol Psychiatry. 2003 Sep 1; 54(5):566-72.
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      261. Yaffe K, Edwards ER, Covinsky KE, Lui LY, Eng C. Depressive symptoms and risk of mortality in frail, community-living elderly persons. Am J Geriatr Psychiatry. 2003 Sep-Oct; 11(5):561-7.
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      262. Schuff N, Capizzano AA, Du AT, Amend DL, O'Neill J, Norman D, Jagust WJ, Chui HC, Kramer JH, Reed BR, Miller BL, Yaffe K, Weiner MW. Different patterns of N-acetylaspartate loss in subcortical ischemic vascular dementia and AD. Neurology. 2003 Aug 12; 61(3):358-64.
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      263. Yaffe K, Lindquist K, Penninx BW, Simonsick EM, Pahor M, Kritchevsky S, Launer L, Kuller L, Rubin S, Harris T. Inflammatory markers and cognition in well-functioning African-American and white elders. Neurology. 2003 Jul 8; 61(1):76-80.
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      264. Yaffe K. Hormone therapy and the brain: déjà vu all over again? JAMA. 2003 May 28; 289(20):2717-9.
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      265. Newcomer R, Covinsky KE, Clay T, Yaffe K. Predicting 12-month mortality for persons with dementia. J Gerontol B Psychol Sci Soc Sci. 2003 May; 58(3):S187-98.
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      266. Mehta KM, Yaffe K, Langa KM, Sands L, Whooley MA, Covinsky KE. Additive effects of cognitive function and depressive symptoms on mortality in elderly community-living adults. J Gerontol A Biol Sci Med Sci. 2003 May; 58(5):M461-7.
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      267. Wolkowitz OM, Kramer JH, Reus VI, Costa MM, Yaffe K, Walton P, Raskind M, Peskind E, Newhouse P, Sack D, De Souza E, Sadowsky C, Roberts E. DHEA treatment of Alzheimer's disease: a randomized, double-blind, placebo-controlled study. Neurology. 2003 Apr 8; 60(7):1071-6.
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      268. Barnes DE, Yaffe K, Satariano WA, Tager IB. A longitudinal study of cardiorespiratory fitness and cognitive function in healthy older adults. J Am Geriatr Soc. 2003 Apr; 51(4):459-65.
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      269. Covinsky KE, Eng C, Lui LY, Sands LP, Yaffe K. The last 2 years of life: functional trajectories of frail older people. J Am Geriatr Soc. 2003 Apr; 51(4):492-8.
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      270. Mehta KM, Simonsick EM, Penninx BW, Schulz R, Rubin SM, Satterfield S, Yaffe K. Prevalence and correlates of anxiety symptoms in well-functioning older adults: findings from the health aging and body composition study. J Am Geriatr Soc. 2003 Apr; 51(4):499-504.
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      271. Barton C, Miller B, Yaffe K. Evaluation of the diagnosis and management of cognitive impairment in long-term care. Alzheimer Dis Assoc Disord. 2003 Apr-Jun; 17(2):72-6.
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      272. Whitmer RA, Haan MN, Miller JW, Yaffe K. Hormone replacement therapy and cognitive performance: the role of homocysteine. J Gerontol A Biol Sci Med Sci. 2003 Apr; 58(4):324-30.
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      273. Du AT, Schuff N, Zhu XP, Jagust WJ, Miller BL, Reed BR, Kramer JH, Mungas D, Yaffe K, Chui HC, Weiner MW. Atrophy rates of entorhinal cortex in AD and normal aging. Neurology. 2003 Feb 11; 60(3):481-6.
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      274. Trinh NH, Hoblyn J, Mohanty S, Yaffe K. Efficacy of cholinesterase inhibitors in the treatment of neuropsychiatric symptoms and functional impairment in Alzheimer disease: a meta-analysis. JAMA. 2003 Jan 8; 289(2):210-6.
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      275. Sands LP, Yaffe K, Covinsky K, Chren MM, Counsell S, Palmer R, Fortinsky R, Landefeld CS. Cognitive screening predicts magnitude of functional recovery from admission to 3 months after discharge in hospitalized elders. J Gerontol A Biol Sci Med Sci. 2003 Jan; 58(1):37-45.
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      276. Kramer JH, Yaffe K, Lengenfelder J, Delis DC. Age and gender interactions on verbal memory performance. J Int Neuropsychol Soc. 2003 Jan; 9(1):97-102.
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      277. Lui LY, Stone K, Cauley JA, Hillier T, Yaffe K. Bone loss predicts subsequent cognitive decline in older women: the study of osteoporotic fractures. J Am Geriatr Soc. 2003 Jan; 51(1):38-43.
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      278. Grundman M, Jack CR, Petersen RC, Kim HT, Taylor C, Datvian M, Weiner MF, DeCarli C, DeKosky ST, van Dyck C, Darvesh S, Yaffe K, Kaye J, Ferris SH, Thomas RG, Thal LJ. Hippocampal volume is associated with memory but not monmemory cognitive performance in patients with mild cognitive impairment. J Mol Neurosci. 2003; 20(3):241-8.
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      279. Grady D, Yaffe K, Kristof M, Lin F, Richards C, Barrett-Connor E. Effect of postmenopausal hormone therapy on cognitive function: the Heart and Estrogen/progestin Replacement Study. Am J Med. 2002 Nov; 113(7):543-8.
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      280. Sands LP, Yaffe K, Lui LY, Stewart A, Eng C, Covinsky K. The effects of acute illness on ADL decline over 1 year in frail older adults with and without cognitive impairment. J Gerontol A Biol Sci Med Sci. 2002 Jul; 57(7):M449-54.
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      281. Du AT, Schuff N, Laakso MP, Zhu XP, Jagust WJ, Yaffe K, Kramer JH, Miller BL, Reed BR, Norman D, Chui HC, Weiner MW. Effects of subcortical ischemic vascular dementia and AD on entorhinal cortex and hippocampus. Neurology. 2002 Jun 11; 58(11):1635-41.
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      282. Mehta KM, Yaffe K, Covinsky KE. Cognitive impairment, depressive symptoms, and functional decline in older people. J Am Geriatr Soc. 2002 Jun; 50(6):1045-50.
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      283. Yaffe K, Fox P, Newcomer R, Sands L, Lindquist K, Dane K, Covinsky KE. Patient and caregiver characteristics and nursing home placement in patients with dementia. JAMA. 2002 Apr 24; 287(16):2090-7.
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      284. Yaffe K, Lui LY, Grady D, Stone K, Morin P. Estrogen receptor 1 polymorphisms and risk of cognitive impairment in older women. Biol Psychiatry. 2002 Apr 15; 51(8):677-82.
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      285. Yaffe K, Lui LY, Zmuda J, Cauley J. Sex hormones and cognitive function in older men. J Am Geriatr Soc. 2002 Apr; 50(4):707-12.
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      286. Schuff N, Capizzano AA, Du AT, Amend DL, O'Neill J, Norman D, Kramer J, Jagust W, Miller B, Wolkowitz OM, Yaffe K, Weiner MW. Selective reduction of N-acetylaspartate in medial temporal and parietal lobes in AD. Neurology. 2002 Mar 26; 58(6):928-35.
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      287. Yaffe K, Barrett-Connor E, Lin F, Grady D. Serum lipoprotein levels, statin use, and cognitive function in older women. Arch Neurol. 2002 Mar; 59(3):378-84.
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      288. Yaffe K. Estrogens, selective estrogen receptor modulators, and dementia: what is the evidence? Ann N Y Acad Sci. 2001 Dec; 949:215-22.
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      289. Covinsky KE, Eng C, Lui LY, Sands LP, Sehgal AR, Walter LC, Wieland D, Eleazer GP, Yaffe K. Reduced employment in caregivers of frail elders: impact of ethnicity, patient clinical characteristics, and caregiver characteristics. J Gerontol A Biol Sci Med Sci. 2001 Nov; 56(11):M707-13.
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      290. Du AT, Schuff N, Amend D, Laakso MP, Hsu YY, Jagust WJ, Yaffe K, Kramer JH, Reed B, Norman D, Chui HC, Weiner MW. Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease. J Neurol Neurosurg Psychiatry. 2001 Oct; 71(4):441-7.
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      291. Yaffe K, Barnes D, Nevitt M, Lui LY, Covinsky K. A prospective study of physical activity and cognitive decline in elderly women: women who walk. Arch Intern Med. 2001 Jul 23; 161(14):1703-8.
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      292. Yaffe K, Krueger K, Sarkar S, Grady D, Barrett-Connor E, Cox DA, Nickelsen T. Cognitive function in postmenopausal women treated with raloxifene. N Engl J Med. 2001 Apr 19; 344(16):1207-13.
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      293. Yaffe K, Lui LY, Grady D, Cauley J, Kramer J, Cummings SR. Cognitive decline in women in relation to non-protein-bound oestradiol concentrations. Lancet. 2000 Aug 26; 356(9231):708-12.
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      294. Yaffe K, Haan M, Byers A, Tangen C, Kuller L. Estrogen use, APOE, and cognitive decline: evidence of gene-environment interaction. Neurology. 2000 May 23; 54(10):1949-54.
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      295. Kusdra L, Rempel H, Yaffe K, Pulliam L. Elevation of CD69+ monocyte/macrophages in patients with Alzheimer's disease. Immunobiology. 2000 May; 202(1):26-33.
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      296. Covinsky KE, Fuller JD, Yaffe K, Johnston CB, Hamel MB, Lynn J, Teno JM, Phillips RS. Communication and decision-making in seriously ill patients: findings of the SUPPORT project. The Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments. J Am Geriatr Soc. 2000 May; 48(5 Suppl):S187-93.
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      297. Yaffe K, Browner W, Cauley J, Launer L, Harris T. Association between bone mineral density and cognitive decline in older women. J Am Geriatr Soc. 1999 Oct; 47(10):1176-82.
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      298. Yaffe K, Blackwell T, Gore R, Sands L, Reus V, Browner WS. Depressive symptoms and cognitive decline in nondemented elderly women: a prospective study. Arch Gen Psychiatry. 1999 May; 56(5):425-30.
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