Kara Lynch, PhD

Title(s)Professor, Laboratory Medicine
SchoolSchool of Medicine
Address2540 23rd Street, #2801
San Francisco CA 94110
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    Collapse Biography 
    Collapse Education and Training
    Butler UniversityBachelor of Science2002Chemistry and Biology Departments
    University of WisconsinDoctorate2007Biochemistry Department
    University of California, San FranciscoPostdoctoral Studies2009Graduate Division

    Collapse Overview 
    Collapse Overview
    Dr. Lynch is the Co-Director of the Core Clinical Laboratory at San Francisco General Hospital overseeing Chemistry and Toxicology. She is also the Director of Chemistry at UCSF Children's Hospital Oakland. Her research laboratory primarily focuses on identifying and quantifying endogenous and exogenous compounds in biological specimens using novel diagnostic technologies, such as mass spectrometry and biolayer interferometry, and correlating the findings with clinical pathologies. They are involved in translational research studies aimed at the clinical evaluation of novel biomarkers or biomarker panels to diagnosis, treat and monitor disease. The Lynch lab has developed numerous liquid-chromatography tandem mass spectrometry (LC-MS/MS), liquid-chromatography quadrupole time-of-flight (LC-QTOF) mass spectrometry, and label-free immunoassay methods for the detection and quantitation of small molecules and proteins in biological specimens. The methods they develop are used to investigate perturbations in metabolic pathways caused by disease and toxicological exposure. They aim to translate results into information that can be used in clinical practice bridging laboratory research and clinical research through multidisciplinary collaboration and methodologies.

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Testing the test strips: laboratory performance of fentanyl test strips. Harm Reduct J. 2024 Jan 18; 21(1):14. Halifax JC, Lim L, Ciccarone D, Lynch KL. PMID: 38238757; PMCID: PMC10795297.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2. Nat Immunol. 2024 Feb; 25(2):218-225. Yin K, Peluso MJ, Luo X, Thomas R, Shin MG, Neidleman J, Andrew A, Young KC, Ma T, Hoh R, Anglin K, Huang B, Argueta U, Lopez M, Valdivieso D, Asare K, Deveau TM, Munter SE, Ibrahim R, Ständker L, Lu S, Goldberg SA, Lee SA, Lynch KL, Kelly JD, Martin JN, Münch J, Deeks SG, Henrich TJ, Roan NR. PMID: 38212464; PMCID: PMC10834368.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    3. The role of substance use in structural heart disease among women living with HIV. J Acquir Immune Defic Syndr. 2023 Dec 19. Riley ED, Vittinghoff E, Ravi A, Coffin PO, Lynch K, Wu AHB, Martinez C, Hsue PY. PMID: 38133589.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. The Effect of Route of Administration and Vehicle on the Pharmacokinetics of THC and CBD in Adult, Neonate, and Breastfed Sprague-Dawley Rats. Cannabis Cannabinoid Res. 2023 Oct 18. Soni I, Chinn GA, Halifax JC, Hellman J, Lynch KL, Sall JW. PMID: 37852006.
      View in: PubMed   Mentions:    Fields:    
    5. Cocaine Use is Associated With Increased LVMI in Unstably Housed Women With Polysubstance Use. Subst Abus. 2023 10; 44(4):323-329. Ravi A, Vittinghoff E, Wu AHB, Suen LW, Coffin PO, Hsue P, Lynch KL, Win S, Kazi DS, Riley ED. PMID: 37830512.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Comparison of liquid chromatography-high-resolution tandem mass spectrometry (MS2) and multi-stage mass spectrometry (MS3) for screening toxic natural products. J Mass Spectrom Adv Clin Lab. 2023 Nov; 30:38-44. Luo RY, Comstock K, Ding C, Wu AHB, Lynch KL. PMID: 37876549; PMCID: PMC10590993.
      View in: PubMed   Mentions:
    7. Long COVID manifests with T cell dysregulation, inflammation, and an uncoordinated adaptive immune response to SARS-CoV-2. bioRxiv. 2023 Aug 04. Yin K, Peluso MJ, Luo X, Thomas R, Shin MG, Neidleman J, Andrew A, Young K, Ma T, Hoh R, Anglin K, Huang B, Argueta U, Lopez M, Valdivieso D, Asare K, Deveau TM, Munter SE, Ibrahim R, Ständker L, Lu S, Goldberg SA, Lee SA, Lynch KL, Kelly JD, Martin JN, Münch J, Deeks SG, Henrich TJ, Roan NR. PMID: 36798286; PMCID: PMC9934605.
      View in: PubMed   Mentions:
    8. A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection. Nature. 2023 Aug; 620(7972):128-136. Augusto DG, Murdolo LD, Chatzileontiadou DSM, Sabatino JJ, Yusufali T, Peyser ND, Butcher X, Kizer K, Guthrie K, Murray VW, Pae V, Sarvadhavabhatla S, Beltran F, Gill GS, Lynch KL, Yun C, Maguire CT, Peluso MJ, Hoh R, Henrich TJ, Deeks SG, Davidson M, Lu S, Goldberg SA, Kelly JD, Martin JN, Vierra-Green CA, Spellman SR, Langton DJ, Dewar-Oldis MJ, Smith C, Barnard PJ, Lee S, Marcus GM, Olgin JE, Pletcher MJ, Maiers M, Gras S, Hollenbach JA. PMID: 37468623; PMCID: PMC10396966.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    9. Assessment of Adverse Reactions, Antibody Patterns, and 12-month Outcomes in the Mother-Infant Dyad After COVID-19 mRNA Vaccination in Pregnancy. JAMA Netw Open. 2023 Jul 03; 6(7):e2323405. Cassidy AG, Li L, Golan Y, Gay C, Lin CY, Jigmeddagva U, Chidboy MA, Ilala M, Buarpung S, Gonzalez VJ, Basilio E, Duck M, Murtha AP, Wu AHB, Lynch KL, Asiodu IV, Prahl MK, Gaw SL. PMID: 37450302; PMCID: PMC10349345.
      View in: PubMed   Mentions: 4     Fields:    
    10. Predictive Value of ABCC2 and UGT1A1 Polymorphisms on Irinotecan-Related Toxicities in Patients with Cancer. Genet Test Mol Biomarkers. 2023 May; 27(5):133-141. Aoullay Z, Smith A, Slaoui M, El Bouchikhi I, Ghazal H, Al Idrissi N, Meddah B, Lynch KL, Cherrah Y, Wu AHB. PMID: 37257181.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. A case series evaluation of comprehensive drug testing in the pediatric acute care setting. J Mass Spectrom Adv Clin Lab. 2023 Apr; 28:75-79. Lynch KL. PMID: 36909288; PMCID: PMC9995460.
      View in: PubMed   Mentions:
    12. Unexpected Fentanyl Detection during a Liver Transplant Evaluation. Clin Chem. 2023 03 01; 69(3):222-225. Fitch BA, Lynch KL, Liao HC. PMID: 36857214.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Multiple substance use and blood pressure in women experiencing homelessness. Addict Behav Rep. 2023 Jun; 17:100483. Suen LW, Vittinghoff E, Wu AHB, Ravi A, Coffin PO, Hsue P, Lynch KL, Kazi DS, Riley ED. PMID: 36875801; PMCID: PMC9975611.
      View in: PubMed   Mentions: 1  
    14. Development of a Machine Learning Algorithm for Drug Screening Analysis on High-Resolution UPLC-MSE/QTOF Mass Spectrometry. J Appl Lab Med. 2023 01 04; 8(1):53-66. Hao Y, Lynch K, Fan P, Jurtschenko C, Cid M, Zhao Z, Yang HS. PMID: 36610415.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    15. Detection of IgM, IgG, IgA and neutralizing antibody responses to SARS-CoV-2 infection and mRNA vaccination. J Med Microbiol. 2023 Jan; 72(1). Fleischmann CJ, Bulman CA, Yun C, Lynch KL, Wu AHB, Whitman JD. PMID: 36748419.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    16. Transient expression of antinuclear RNP-A antibodies in patients with acute COVID-19 infection. J Transl Autoimmun. 2022; 5:100175. Zhou S, Kaul R, Lynch KL, Wu AHB, Walker RP. PMID: 36447819; PMCID: PMC9686057.
      View in: PubMed   Mentions:
    17. An Opioid Hiding in Plain Sight: Loperamide-Induced False-Positive Fentanyl and Buprenorphine Immunoassay Results. J Appl Lab Med. 2022 Oct 29; 7(6):1318-1328. Geno KA, Badea A, Lynch KL, Jannetto P, Hubbard JA, Nerenz RD, Cervinski MA. PMID: 36036092.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. Autoantibody discovery across monogenic, acquired, and COVID-19-associated autoimmunity with scalable PhIP-seq. Elife. 2022 10 27; 11. Vazquez SE, Mann SA, Bodansky A, Kung AF, Quandt Z, Ferré EMN, Landegren N, Eriksson D, Bastard P, Zhang SY, Liu J, Mitchell A, Proekt I, Yu D, Mandel-Brehm C, Wang CY, Miao B, Sowa G, Zorn K, Chan AY, Tagi VM, Shimizu C, Tremoulet A, Lynch K, Wilson MR, Kämpe O, Dobbs K, Delmonte OM, Bacchetta R, Notarangelo LD, Burns JC, Casanova JL, Lionakis MS, Torgerson TR, Anderson MS, DeRisi JL. PMID: 36300623; PMCID: PMC9711525.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    19. Impact of multiple substance use on circulating ST2, a biomarker of adverse cardiac remodelling, in women. Biomarkers. 2022 Dec; 27(8):802-808. Riley ED, Kazi DS, Coffin PO, Vittinghoff E, Wade AN, Bulfone TC, Lynch KL, Atai Z, Wu AHB. PMID: 36168954; PMCID: PMC9744090.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Hospitalized Patients With COVID-19 Have Higher Plasma Aldosterone-Renin Ratio and Lower ACE Activity Than Controls. J Endocr Soc. 2022 Oct 26; 6(12):bvac144. Parikh NI, Arowolo F, Durstenfeld MS, Nah G, Njoroge J, Vittinghoff E, Long CS, Ganz P, Pearce D, Hsue P, Wu AHS, Hajizadeh N, Liu KD, Lynch KL. PMID: 36338506; PMCID: PMC9619433.
      View in: PubMed   Mentions: 1  
    21. Differences in Post-mRNA Vaccination Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Immunoglobulin G (IgG) Concentrations and Surrogate Virus Neutralization Test Response by Human Immunodeficiency Virus (HIV) Status and Type of Vaccine: A Matched Case-Control Observational Study. Clin Infect Dis. 2022 Aug 24; 75(1):e916-e919. Spinelli MA, Peluso MJ, Lynch KL, Yun C, Glidden DV, Henrich TJ, Deeks SG, Gandhi M. PMID: 34864962; PMCID: PMC8689738.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCellsPHPublic Health
    22. Abstract P3005: Cannabinoid Receptor 1 Antagonist Genistein Attenuates Marijuana-Induced Vascular Inflammation. Circulation Research. 2022 Aug 5; 131(Suppl_1):ap3005-ap3005. Chandy CM, Wei WT, Nishiga NM, Zhang ZA, Kumar KK, Thomas TD, Manhas MA, Rhee RS, Justesen JJ, Chen CI, Wo WH, Yang YJ, Khanamiri KS, Seidl SF, Burns BN, Liu LC, Sayed SN, Shie SJ, Yeh YC, YANG YK, Lau LE, Lynch LK, Rivas RM, Kobilka KB, Wu WJ. .
      View in: Publisher Site   Mentions:
    23. Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and infancy. Nat Commun. 2022 07 30; 13(1):4422. Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J, Gaw SL. PMID: 35908075; PMCID: PMC9338928.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    24. The Pharmacokinetics of Ketamine in the Breast Milk of Lactating Women: Quantification of Ketamine and Metabolites. J Psychoactive Drugs. 2023 Jul-Aug; 55(3):354-358. Wolfson P, Cole R, Lynch K, Yun C, Wallach J, Andries J, Whippo M. PMID: 35880962.
      View in: PubMed   Mentions: 2     Fields:    
    25. Development and application of a High-Resolution mass spectrometry method for the detection of fentanyl analogs in urine and serum. J Mass Spectrom Adv Clin Lab. 2022 Nov; 26:1-6. Zhang Y, Halifax JC, Tangsombatvisit C, Yun C, Pang S, Hooshfar S, Wu AHB, Lynch KL. PMID: 36065325; PMCID: PMC9440429.
      View in: PubMed   Mentions: 4  
    26. Postacute sequelae and adaptive immune responses in people with HIV recovering from SARS-COV-2 infection. AIDS. 2022 10 01; 36(12):F7-F16. Peluso MJ, Spinelli MA, Deveau TM, Forman CA, Munter SE, Mathur S, Tang AF, Lu S, Goldberg SA, Arreguin MI, Hoh R, Tai V, Chen JY, Martinez EO, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Sette A, Weiskopf D, Kumar N, Lynch KL, Hunt PW, Durstenfeld MS, Hsue PY, Kelly JD, Martin JN, Glidden DV, Gandhi M, Deeks SG, Rutishauser RL, Henrich TJ. PMID: 35866847; PMCID: PMC9444925.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    27. Multiple substance use, inflammation and cardiac stretch in women living with HIV. Drug Alcohol Depend. 2022 09 01; 238:109564. Riley ED, Kizer JR, Tien PC, Vittinghoff E, Lynch KL, Wu AHB, Coffin PO, Beck-Engeser G, Braun C, Hunt PW. PMID: 35872529; PMCID: PMC9924802.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. Increased Serum IgG Antibody, Avidity, and Surrogate Virus Neutralization Response after a Third Dose for the BNT162b2 mRNA Vaccine to SARS-CoV-2. J Appl Lab Med. 2022 06 30; 7(4):995-997. Wu AHB, Lynch KL. PMID: 35661895; PMCID: PMC9384200.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    29. Evaluation of Neutralizing Antibodies against SARS-CoV-2 Variants after Infection and Vaccination Using a Multiplexed Surrogate Virus Neutralization Test. Clin Chem. 2022 05 18; 68(5):702-712. Lynch KL, Zhou S, Kaul R, Walker R, Wu AH. PMID: 35018416; PMCID: PMC8755391.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsPHPublic Health
    30. Adequate Antibody Response to COVID-19 Vaccine in Patients with Monoclonal Gammopathies and Light Chain Amyloidosis. Lab Med. 2022 May 05; 53(3):314-319. Wu AHB, Wang CC, Ong CM, Lynch KL. PMID: 35026018; PMCID: PMC8807219.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    31. Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. Cell. 2022 05 12; 185(10):1676-1693.e23. Wei TT, Chandy M, Nishiga M, Zhang A, Kumar KK, Thomas D, Manhas A, Rhee S, Justesen JM, Chen IY, Wo HT, Khanamiri S, Yang JY, Seidl FJ, Burns NZ, Liu C, Sayed N, Shie JJ, Yeh CF, Yang KC, Lau E, Lynch KL, Rivas M, Kobilka BK, Wu JC. PMID: 35489334; PMCID: PMC9400797.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    32. Establishment of a High-Resolution Liquid Chromatography-Mass Spectrometry Spectral Library for Screening Toxic Natural Products. J Anal Toxicol. 2022 Mar 21; 46(3):303-321. Luo YR, Goodnough R, Yun C, Wu AHB, Lynch KL. PMID: 33506876.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    33. Rate of Serum SARS-CoV-2 Antibody Decline for Two mRNA Vaccines. J Appl Lab Med. 2022 03 02; 7(2):625-627. Wu AHB, Nguyen ED, Ong CM, Yun C, Lynch KL. PMID: 34648027; PMCID: PMC8524641.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    34. Longitudinal SARS-CoV-2 Antibody Avidity Responses in a SARS-CoV-2 Pregnancy Cohort. American Journal of Obstetrics and Gynecology. 2022 Jan 26; 226(2):297-298. Cassidy CA, Prahl PM, Song SD, Jegatheesan JP, Lynch LK, Gaw GS. .
      View in: Publisher Site   Mentions:
    35. Development of an LC-MS/MS Method for Measurement of Irinotecan and Its Major Metabolites in Plasma: Technical Considerations. Lab Med. 2022 Jan 06; 53(1):47-52. Aoullay Z, Van Wijk XMR, Yanhui M, Meddah B, Lynch KL, Cherrah Y, Wu AHB. PMID: 34351422.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Development of a high-throughput differential mobility separation-tandem mass spectrometry (DMS-MS/MS) method for clinical urine drug testing. J Mass Spectrom Adv Clin Lab. 2022 Jan; 23:50-57. Hooshfar S, Tchu S, Yun C, Lynch KL. PMID: 35036987; PMCID: PMC8753179.
      View in: PubMed   Mentions: 2  
    37. Diagnostic Value of Nucleocapsid Protein in Blood for SARS-CoV-2 Infection. Clin Chem. 2021 12 30; 68(1):240-248. Zhang Y, Ong CM, Yun C, Mo W, Whitman JD, Lynch KL, Wu AHB. PMID: 34358289; PMCID: PMC8436384.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    38. Refractory vasodilatory shock secondary to metformin overdose supported with VA ECMO. Toxicol Rep. 2022; 9:64-67. Ives Tallman C, Zhang Y, Black N, Lynch K, Fayed M, Armenian P. PMID: 35004183; PMCID: PMC8718576.
      View in: PubMed   Mentions: 3  
    39. Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy. Res Sq. 2021 Dec 15. Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J, Gaw SL. PMID: 34931183; PMCID: PMC8687466.
      View in: PubMed   Mentions:
    40. Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy. medRxiv. 2021 Dec 13. Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J, Gaw SL. PMID: 34931197; PMCID: PMC8687468.
      View in: PubMed   Mentions: 2  
    41. LB8. Lower SARS-CoV-2 IgG and Pseudovirus Neutralization Titers Post-mRNA Vaccination among People Living with HIV. Open Forum Infectious Diseases. 2021 Dec 4; 8(Suppl 1):s805-s805. Spinelli SM, Peluso PM, Lynch LK, Yun YC, Glidden GD, Henrich HT, Deeks DS, Gandhi GM. .
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    42. Mistaken identity: acute respiratory arrest from accidental ingestion of poison hemlock. Clin Toxicol (Phila). 2022 05; 60(5):659-661. Li K, Bassett H, Fitch B, Lynch K. PMID: 34787039.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    43. Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibody Avidity Maturation and Association with Disease Severity. Clin Infect Dis. 2021 11 02; 73(9):e3095-e3097. Luo YR, Chakraborty I, Yun C, Wu AHB, Lynch KL. PMID: 32927483; PMCID: PMC7543300.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    44. The Reference Range for the Anion Gap Is Dependent on the Instrument's Electrolyte Assay. J Appl Lab Med. 2021 11 01; 6(6):1697-1699. Wu AHB, Jankowski T, Zhang Y, Lynch KL. PMID: 34534316.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    45. Longitudinal Study of SARS-CoV-2 Antibody Characteristics Using Label-Free Immunoassays. American Journal of Clinical Pathology. 2021 Oct 28; 156(Supplement_1):s32-s32. Luo LY, Yun YC, Wu WA, Lynch LK, Chakraborty CI. .
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    46. SARS-CoV-2 spike protein induces abnormal inflammatory blood clots neutralized by fibrin immunotherapy. bioRxiv. 2021 Oct 13. Ryu JK, Sozmen EG, Dixit K, Montano M, Matsui Y, Liu Y, Helmy E, Deerinck TJ, Yan Z, Schuck R, Acevedo RM, Spencer CM, Thomas R, Pico AR, Zamvil SS, Lynch KL, Ellisman MH, Greene WC, Akassoglou K. PMID: 34671772; PMCID: PMC8528086.
      View in: PubMed   Mentions: 1  
    47. Ongoing tobacco use in women who experience homelessness and unstable housing: A prospective study to inform tobacco cessation interventions and policies. Addictive Behaviors. 2021 Sep 1; 107125. Riley RE, Delucchi DK, Rubin RS, Weiser WS, Vijayaraghavan VM, Lynch LK, Tsoh TJ. .
      View in: Publisher Site   Mentions:
    48. Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19. Sci Transl Med. 2021 Sep 22; 13(612):eabh2624. van der Wijst MGP, Vazquez SE, Hartoularos GC, Bastard P, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Mann SA, Lynch KL, Yun C, Havlir DV, Chamie G, Marquez C, Greenhouse B, Lionakis MS, Norris PJ, Dumont LJ, Kelly K, Zhang P, Zhang Q, Gervais A, Le Voyer T, Whatley A, Si Y, Byrne A, Combes AJ, Rao AA, Song YS, Fragiadakis GK, Kangelaris K, Calfee CS, Erle DJ, Hendrickson C, Krummel MF, Woodruff PG, Langelier CR, Casanova JL, Derisi JL, Anderson MS, Ye CJ, UCSF COMET consortium. PMID: 34429372; PMCID: PMC8601717.
      View in: PubMed   Mentions: 107     Fields:    Translation:Humans
    49. Discordant Virus-Specific Antibody Levels, Antibody Neutralization Capacity, and T-cell Responses Following 3 Doses of SARS-CoV-2 Vaccination in a Patient With Connective Tissue Disease. Open Forum Infect Dis. 2021 Aug; 8(8):ofab393. Peluso MJ, Munter SE, Lynch KL, Yun C, Torres L, Iyer NS, Donatelli J, Ryan L, Deitchman AN, Deeks SG, Rutishauser RL, Henrich TJ. PMID: 34395717; PMCID: PMC8344490.
      View in: PubMed   Mentions: 2  
    50. Characteristics of High-Titer Convalescent Plasma and Antibody Dynamics After Administration in Patients With Severe Coronavirus Disease 2019. Open Forum Infect Dis. 2021 Aug; 8(8):ofab385. Bainbridge ED, Hsue PY, Esensten JH, Lynch KL, Hendrickson CM, Doernberg SB, Fung M, Chin-Hong P, Di Germanio C, Norris PJ, Simmons G, Glidden DV, Luetkemeyer AF. PMID: 34405093; PMCID: PMC8344822.
      View in: PubMed   Mentions: 3  
    51. Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19. Cell Rep. 2021 07 20; 36(3):109414. Neidleman J, Luo X, George AF, McGregor M, Yang J, Yun C, Murray V, Gill G, Greene WC, Vasquez J, Lee SA, Ghosn E, Lynch KL, Roan NR. PMID: 34260965; PMCID: PMC8238659.
      View in: PubMed   Mentions: 49     Fields:    
    52. A SARS-CoV-2 Label-Free Surrogate Virus Neutralization Test and a Longitudinal Study of Antibody Characteristics in COVID-19 Patients. J Clin Microbiol. 2021 06 18; 59(7):e0019321. Luo YR, Yun C, Chakraborty I, Wu AHB, Lynch KL. PMID: 33827900; PMCID: PMC8218741.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    53. Citywide serosurveillance of the initial SARS-CoV-2 outbreak in San Francisco using electronic health records. Nat Commun. 2021 06 11; 12(1):3566. Routledge I, Epstein A, Takahashi S, Janson O, Hakim J, Duarte E, Turcios K, Vinden J, Sujishi K, Rangel J, Coh M, Besana L, Ho WK, Oon CY, Ong CM, Yun C, Lynch K, Wu AHB, Wu W, Karlon W, Thornborrow E, Peluso MJ, Henrich TJ, Pak JE, Briggs J, Greenhouse B, Rodriguez-Barraquer I. PMID: 34117227; PMCID: PMC8195995.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCellsPHPublic Health
    54. Lacosamide induced Brugada I morphology in the setting of septicemia: A case report. Medicine (Baltimore). 2021 May 07; 100(18):e25577. Goodnough R, Badea A, Geier C, Lynch KL, LeSaint KT. PMID: 33950934; PMCID: PMC8104292.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    55. SARS-CoV-2 seroprevalence, and IgG concentration and pseudovirus neutralising antibody titres after infection, compared by HIV status: a matched case-control observational study. Lancet HIV. 2021 06; 8(6):e334-e341. Spinelli MA, Lynch KL, Yun C, Glidden DV, Peluso MJ, Henrich TJ, Gandhi M, Brown LB. PMID: 33933189; PMCID: PMC8084354.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    56. Evaluation of Biomarkers in Sepsis: High Dimethylarginine (ADMA and SDMA) Concentrations Are Associated with Mortality. J Appl Lab Med. 2021 04 29; 6(3):592-605. van Wijk XMR, Yun C, Lynch KL. PMID: 33382901.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    57. Hospital-Based Donor Recruitment and Predonation Serologic Testing for COVID-19 Convalescent Plasma. Am J Clin Pathol. 2021 Mar 15; 155(4):515-521. Balcerek J, Trejo E, Levine K, Couey P, Kornberg ZV, Rogine C, Young C, Li PJ, Shy BR, Taylor JE, Bakhtary S, Friedlander T, Lynch KL, Bern C, Esensten JH. PMID: 33399201; PMCID: PMC7929413.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    58. Lack of Cross-Reactivity of Tianeptine with Tricyclic Antidepressant Immunoassays. J Anal Toxicol. 2021 Mar 12; 45(3):e8-e9. Badea A, Ghosh R, Lynch KL, Wu AHB. PMID: 33410462.
      View in: PubMed   Mentions:    Fields:    
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    65. Impact of polysubstance use on high-sensitivity cardiac troponin I over time in homeless and unstably housed women. Drug Alcohol Depend. 2020 12 01; 217:108252. Riley ED, Vittinghoff E, Wu AHB, Coffin PO, Hsue PY, Kazi DS, Wade A, Braun C, Lynch KL. PMID: 32919207; PMCID: PMC7873814.
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    72. A case of unexplained duodenal ulcer and massive gastrointestinal bleed. Clin Chim Acta. 2020 Jul; 506:188-190. Luo YR, Goodnough R, Menza R, Badea A, Luu HY, Kornblith LZ, Lynch KL. PMID: 32234495; PMCID: PMC9055633.
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    74. Real-time comprehensive toxicology testing in the clinical management of accidental pediatric capecitabine ingestion. J Oncol Pharm Pract. 2020 Oct; 26(7):1759-1761. Gintjee TJ, Goodnough R, Li K, Badea A, Lynch KL, Garcia E, Repplinger D. PMID: 32089072.
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    75. A thin-film interferometry-based label-free immunoassay for the detection of daratumumab interference in serum protein electrophoresis. Clin Chim Acta. 2020 Mar; 502:128-132. Luo YR, Chakraborty I, Zuk RF, Lynch KL, Wu AHB. PMID: 31883925.
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    76. Quantitative biochemical screening for marijuana use and concordance with tobacco use in urban adolescents. Drug Alcohol Depend. 2019 12 01; 205:107583. Benowitz N, Nardone N, St Helen G, Addo N, Jacob P, Liakoni E, Jain S, Hooshfar S, Lynch K. PMID: 31600618; PMCID: PMC6893148.
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    78. Correlation of Breath and Blood Δ9-Tetrahydrocannabinol Concentrations and Release Kinetics Following Controlled Administration of Smoked Cannabis. Clin Chem. 2019 09; 65(9):1171-1179. Lynch KL, Luo YR, Hooshfar S, Yun C. PMID: 31296552.
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    82. A Liquid-Chromatography High-Resolution Mass Spectrometry Method for Non-FDA Approved Benzodiazepines. J Anal Toxicol. 2019 May 01; 43(4):316-320. van Wijk XMR, Yun C, Hooshfar S, Arens AM, Lung D, Wu AHB, Lynch KL. PMID: 30462225.
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    83. Optimization and Comparison of Information-Dependent Acquisition (IDA) to Sequential Window Acquisition of All Theoretical Fragment Ion Spectra (SWATH) for High-Resolution Mass Spectrometry in Clinical Toxicology. Clin Chem. 2019 07; 65(7):862-870. Whitman JD, Lynch KL. PMID: 30996055.
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    84. Azo coupling-based derivatization method for high-sensitivity liquid chromatography-tandem mass spectrometry analysis of tetrahydrocannabinol and other aromatic compounds. J Chromatogr A. 2019 Jul 19; 1597:109-118. Luo YR, Han J, Yun C, Lynch KL. PMID: 30910385.
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    86. Drug Screening Using Liquid Chromatography Quadrupole Time-of-Flight (LC-QqTOF) Mass Spectrometry. Methods Mol Biol. 2019; 1872:181-190. Colby JM, Lynch KL. PMID: 30350290.
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    88. Accreditation and Quality Assurance for Clinical Liquid Chromatography-Mass Spectrometry Laboratories. Clin Lab Med. 2018 09; 38(3):515-526. Lynch KL. PMID: 30115395.
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    89. Notes from the Field: Toxic Leukoencephalopathy Associated with Tianeptine Misuse - California, 2017. MMWR Morb Mortal Wkly Rep. 2018 Jul 13; 67(27):769-770. Goodnough R, Li K, Fouladkou F, Lynch KL, Shah M, Smollin CG, Blanc PD. PMID: 30001559; PMCID: PMC6047469.
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    90. Suspect Screening Using LC-QqTOF Is a Useful Tool for Detecting Drugs in Biological Samples. J Anal Toxicol. 2018 May 01; 42(4):207-213. Colby JM, Thoren KL, Lynch KL. PMID: 29309651.
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    92. Reproducibility Assessment for a Broad Spectrum Drug Screening Method from Urine using Liquid Chromatography Time-of-Flight Mass Spectrometry. Clinical Mass Spectrometry. 2018 Apr 1; 8(Anal Bioanal Chem. 388 2007):1-7. Metushi MI, Wakefield WM, Lynch LK, Stone SJ, Fitzgerald FR. .
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    132. Therapeutic drug monitoring of tamoxifen using LC-MS/MS. Methods Mol Biol. 2012; 902:211-22. Tchu SM, Lynch KL, Wu AH. PMID: 22767121.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    133. Therapeutic Drug Monitoring to Support Clinical Pharmacogenomics. LC-MS in Drug Bioanalysis. 2012 Jan 1; 127-141. Wu WA, Lynch LK. .
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    134. Hydrophilic interaction LC-MS/MS analysis of opioids in urine: significance of glucuronide metabolites. Bioanalysis. 2011 Dec; 3(23):2603-12. French D, Wu A, Lynch K. PMID: 22136049.
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    135. Purpura, cutaneous necrosis, and antineutrophil cytoplasmic antibodies associated with levamisole-adulterated cocaine. Arthritis Rheum. 2011 Dec; 63(12):3998-4001. Graf J, Lynch K, Yeh CL, Tarter L, Richman N, Nguyen T, Kral A, Dominy S, Imboden J. PMID: 22127712.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansPHPublic Health
    136. Rapid screening for the detection of HLA-B57 and HLA-B58 in prevention of drug hypersensitivity. Tissue Antigens. 2011 Jul; 78(1):11-20. Kostenko L, Kjer-Nielsen L, Nicholson I, Hudson F, Lucas A, Foley B, Chen K, Lynch K, Nguyen J, Wu AH, Tait BD, Holdsworth R, Mallal S, Rossjohn J, Bharadwaj M, McCluskey J. PMID: 21501118.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    137. Detection of levamisole exposure in cocaine users by liquid chromatography-tandem mass spectrometry. J Anal Toxicol. 2011 Apr; 35(3):176-8. Lynch KL, Dominy SS, Graf J, Kral AH. PMID: 21439154.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansPHPublic Health
    138. Images in emergency medicine. Adult female with rash on lower extremities. Vasculopathic purpura and neutropenia caused by levamisole-contaminated cocaine. Ann Emerg Med. 2011 Mar; 57(3):307, 311. Lung D, Lynch K, Agrawal S, Armenian P, Banh K. PMID: 21353913.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    139. Vitamin D status of county hospital patients assessed by the DiaSorin LIAISON® 25-hydroxyvitamin D assay. Clin Chim Acta. 2011 Jan 30; 412(3-4):258-62. French D, Gorgi AW, Ihenetu KU, Weeks MA, Lynch KL, Wu AH. PMID: 20965160.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    140. Performance evaluation of three liquid chromatography mass spectrometry methods for broad spectrum drug screening. Clin Chim Acta. 2010 Oct 09; 411(19-20):1474-81. Lynch KL, Breaud AR, Vandenberghe H, Wu AH, Clarke W. PMID: 20540936; PMCID: PMC2914548.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    141. Synaptotagmin-1 utilizes membrane bending and SNARE binding to drive fusion pore expansion. Mol Biol Cell. 2008 Dec; 19(12):5093-103. Lynch KL, Gerona RR, Kielar DM, Martens S, McMahon HT, Martin TF. PMID: 18799625; PMCID: PMC2592635.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    142. Synaptotagmin C2A loop 2 mediates Ca2+-dependent SNARE interactions essential for Ca2+-triggered vesicle exocytosis. Mol Biol Cell. 2007 Dec; 18(12):4957-68. Lynch KL, Gerona RR, Larsen EC, Marcia RF, Mitchell JC, Martin TF. PMID: 17914059; PMCID: PMC2096586.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    143. Synaptotagmins I and IX function redundantly in regulated exocytosis but not endocytosis in PC12 cells. J Cell Sci. 2007 Feb 15; 120(Pt 4):617-27. Lynch KL, Martin TF. PMID: 17264148.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    144. A second SNARE role for exocytic SNAP25 in endosome fusion. Mol Biol Cell. 2006 May; 17(5):2113-24. Aikawa Y, Lynch KL, Boswell KL, Martin TF. PMID: 16481393; PMCID: PMC1446080.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    145. Toward artificial developmental regulators. J Am Chem Soc. 2003 Nov 05; 125(44):13322-3. Arndt HD, Hauschild KE, Sullivan DP, Lake K, Dervan PB, Ansari AZ. PMID: 14583004.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
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