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Clinical dimensions along the non-fluent variant primary progressive aphasia spectrum. Brain. 2024 Apr 04; 147(4):1511-1525.
Illán-Gala I, Lorca-Puls DL, Tee BL, Ezzes Z, de Leon J, Miller ZA, Rubio-Guerra S, Santos-Santos M, Gómez-Andrés D, Grinberg LT, Spina S, Kramer JH, Wauters LD, Henry ML, Boxer AL, Rosen HJ, Miller BL, Seeley WW, Mandelli ML, Gorno-Tempini ML. PMID: 37988272; PMCID: PMC10994525.
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1 Fields:
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Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration. Res Sq. 2024 Mar 28.
Saloner R, Staffaroni A, Dammer E, Johnson ECB, Paolillo E, Wise A, Heuer H, Forsberg L, Lago AL, Webb J, Vogel J, Santillo A, Hansson O, Kramer J, Miller B, Li J, Loureiro J, Sivasankaran R, Worringer K, Seyfried N, Yokoyama J, Seeley W, Spina S, Grinberg L, VandeVrede L, Ljubenkov P, Bayram E, Bozoki A, Brushaber D, Considine C, Day G, Dickerson B, Domoto-Reilly K, Faber K, Galasko D, Geschwind D, Ghoshal N, Graff-Radford N, Hales C, Honig L, Hsiung GY, Huey E, Kornak J, Kremers W, Lapid M, Lee S, Litvan I, McMillan C, Mendez M, Miyagawa T, Pantelyat A, Pascual B, Paulson H, Petrucelli L, Pressman P, Ramos E, Rascovsky K, Roberson E, Savica R, Snyder A, Sullivan AC, Tartaglia C, Vandebergh M, Boeve B, Rosen H, Rojas J, Boxer A, Casaletto K. PMID: 38585969; PMCID: PMC10996789.
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Clinicopathological correlation of cerebrospinal fluid alpha-synuclein seed amplification assay in a behavioral neurology autopsy cohort. Alzheimers Dement. 2024 Mar 27.
Samudra N, Fischer DL, Lenio S, Lario Lago A, Ljubenkov PA, Rojas JC, Seeley WW, Spina S, Staffaroni AM, Tablante J, Wekselman F, Lamoureux J, Concha-Marambio L, Grinberg LT, Boxer AL, VandeVrede L. PMID: 38539061.
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Linking Type and Extent of Head Trauma to Cavum Septum Pellucidum in Older Adults With and Without Alzheimer Disease and Related Dementias. Neurology. 2024 Apr 09; 102(7):e209183.
Asken BM, Tanner JA, Vandevrede L, Apple A, Chapleau M, Gaynor LS, Lane-Donovan C, Lenio S, Yadollahikhales G, Lee S, Gontrum E, Knudtson M, Iaccarino L, La Joie R, Cobigo Y, Staffaroni AM, Casaletto KB, Gardner RC, Grinberg LT, Gorno-Tempini ML, Rosen HJ, Seeley WW, Miller BL, Kramer J, Rabinovici GD. PMID: 38489566.
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Humans
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The wake and sleep-modulating neurons of the lateral hypothalamic area demonstrate a differential pattern of degeneration in Alzheimer's disease. bioRxiv. 2024 Mar 12.
Satpati A, Soloviev AV, Pereira FL, Mladinov M, Larsen E, Leite REP, Suemoto CK, Rodriguez RD, Paes VR, Walsh C, Spina S, Seeley WW, Pasqualucci CA, Filho WJ, Neylan TC, Grinberg LT. PMID: 38559184; PMCID: PMC10979907.
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Alterations in Lysosomal, Glial and Neurodegenerative Biomarkers in Patients with Sporadic and Genetic Forms of Frontotemporal Dementia. bioRxiv. 2024 Feb 12.
Hsiao-Nakamoto J, Chiu CL, VandeVrede L, Ravi R, Vandenberg B, De Groot J, Tsogtbaatar B, Fang M, Auger P, Gould NS, Marchioni F, Powers CA, Davis SS, Suh JH, Alkabsh J, Heuer HW, Lago AL, Scearce-Levie K, Seeley WW, Boeve BF, Rosen HJ, Berger A, Tsai R, Di Paolo G, Boxer AL, Bhalla A, Huang F, ALLFTD Consortium. PMID: 38405775; PMCID: PMC10888909.
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Demographic, clinical, biomarker, and neuropathological correlates of posterior cortical atrophy: an international cohort study and individual participant data meta-analysis. Lancet Neurol. 2024 Feb; 23(2):168-177.
Chapleau M, La Joie R, Yong K, Agosta F, Allen IE, Apostolova L, Best J, Boon BDC, Crutch S, Filippi M, Fumagalli GG, Galimberti D, Graff-Radford J, Grinberg LT, Irwin DJ, Josephs KA, Mendez MF, Mendez PC, Migliaccio R, Miller ZA, Montembeault M, Murray ME, Nemes S, Pelak V, Perani D, Phillips J, Pijnenburg Y, Rogalski E, Schott JM, Seeley W, Sullivan AC, Spina S, Tanner J, Walker J, Whitwell JL, Wolk DA, Ossenkoppele R, Rabinovici GD, PCA International Work Group. PMID: 38267189.
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1 Fields:
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Humans
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KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss. J Clin Invest. 2024 Feb 01; 134(3).
Kauwe G, Pareja-Navarro KA, Yao L, Chen JH, Wong I, Saloner R, Cifuentes H, Nana AL, Shah S, Li Y, Le D, Spina S, Grinberg LT, Seeley WW, Kramer JH, Sacktor TC, Schilling B, Gan L, Casaletto KB, Tracy TE. PMID: 38299587; PMCID: PMC10836803.
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HumansAnimals
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Neural basis of speech and grammar symptoms in non-fluent variant primary progressive aphasia spectrum. Brain. 2024 02 01; 147(2):607-626.
Lorca-Puls DL, Gajardo-Vidal A, Mandelli ML, Illán-Gala I, Ezzes Z, Wauters LD, Battistella G, Bogley R, Ratnasiri B, Licata AE, Battista P, García AM, Tee BL, Lukic S, Boxer AL, Rosen HJ, Seeley WW, Grinberg LT, Spina S, Miller BL, Miller ZA, Henry ML, Dronkers NF, Gorno-Tempini ML. PMID: 37769652; PMCID: PMC10834255.
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Humans
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Spatiotemporal characteristics of neurophysiological changes in patients with four-repeat tauopathies. Ann Clin Transl Neurol. 2024 02; 11(2):525-535.
Samudra N, Lerner H, Yack L, Walsh CM, Kirsch HE, Kudo K, Yballa C, La Joie R, Gorno-Tempini ML, Spina S, Seeley WW, Neylan TC, Miller BL, Rabinovici GD, Boxer A, Grinberg LT, Rankin KP, Nagarajan SS, Ranasinghe KG. PMID: 38226843; PMCID: PMC10863921.
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1 Fields:
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Humans
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Functional network collapse in neurodegenerative disease. bioRxiv. 2023 Dec 06.
Brown JA, Lee AJ, Fernhoff K, Pistone T, Pasquini L, Wise AB, Staffaroni AM, Luisa Mandelli M, Lee SE, Boxer AL, Rankin KP, Rabinovici GD, Luisa Gorno Tempini M, Rosen HJ, Kramer JH, Miller BL, Seeley WW, Alzheimer’s Disease Neuroimaging Initiative (ADNI). PMID: 38106054; PMCID: PMC10723363.
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Mutant tau and stress lead to downregulation of long noncoding RNA, SNHG8. Mol Psychiatry. 2023 Nov; 28(11):4489.
Bhagat R, Minaya MA, Renganathan A, Mehra M, Marsh J, Martinez R, Eteleeb AM, Nana AL, Spina S, Seeley WW, Grinberg LT, Karch CM. PMID: 38443679.
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Cells
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FTLD targets brain regions expressing recently evolved genes. medRxiv. 2023 Oct 28.
Pasquini L, Pereira FL, Seddighi S, Zeng Y, Wei Y, Illán-Gala I, Vatsavayai SC, Friedberg A, Lee AJ, Brown JA, Spina S, Grinberg LT, Sirkis DW, Bonham LW, Yokoyama JS, Boxer AL, Kramer JH, Rosen HJ, Humphrey J, Gitler AD, Miller BL, Pollard KS, Ward ME, Seeley WW. PMID: 37961381; PMCID: PMC10635220.
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1
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Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils. Proc Natl Acad Sci U S A. 2023 10 10; 120(41):e2300258120.
Abskharon R, Pan H, Sawaya MR, Seidler PM, Olivares EJ, Chen Y, Murray KA, Zhang J, Lantz C, Bentzel M, Boyer DR, Cascio D, Nguyen BA, Hou K, Cheng X, Pardon E, Williams CK, Nana AL, Vinters HV, Spina S, Grinberg LT, Seeley WW, Steyaert J, Glabe CG, Ogorzalek Loo RR, Loo JA, Eisenberg DS. PMID: 37801475; PMCID: PMC10576031.
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2 Fields:
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HumansAnimalsCells
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Diminished baseline autonomic outflow in semantic dementia relates to left-lateralized insula atrophy. Neuroimage Clin. 2023; 40:103522.
Hua AY, Roy ARK, Kosik EL, Morris NA, Chow TE, Lukic S, Montembeault M, Borghesani V, Younes K, Kramer JH, Seeley WW, Perry DC, Miller ZA, Rosen HJ, Miller BL, Rankin KP, Gorno-Tempini ML, Sturm VE. PMID: 37820490; PMCID: PMC10582496.
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Humans
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Loss of TDP-43 function contributes to genomic instability in amyotrophic lateral sclerosis. Front Neurosci. 2023; 17:1251228.
Fang M, Deibler SK, Nana AL, Vatsavayai SC, Banday S, Zhou Y, Almeida S, Weiss A, Brown RH, Seeley WW, Gao FB, Green MR. PMID: 37849894; PMCID: PMC10577185.
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Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cell genomics. bioRxiv. 2023 Sep 30.
Rexach JE, Cheng Y, Chen L, Polioudakis D, Lin LC, Mitri V, Elkins A, Yin A, Calini D, Kawaguchi R, Ou J, Huang J, Williams C, Robinson J, Gaus SE, Spina S, Lee EB, Grinberg LT, Vinters H, Trojanowski JQ, Seeley WW, Malhotra D, Geschwind DH. PMID: 37808727; PMCID: PMC10557766.
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Long non-coding RNA SNHG8 drives stress granule formation in tauopathies. Mol Psychiatry. 2023 Nov; 28(11):4889-4901.
Bhagat R, Minaya MA, Renganathan A, Mehra M, Marsh J, Martinez R, Eteleeb AM, Nana AL, Spina S, Seeley WW, Grinberg LT, Karch CM. PMID: 37730840; PMCID: PMC10914599.
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HumansAnimalsCells
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Co-pathology may impact outcomes of amyloid-targeting treatments: clinicopathological results from two patients treated with aducanumab. Acta Neuropathol. 2023 11; 146(5):777-781.
VandeVrede L, La Joie R, Horiki S, Mundada NS, Koestler M, Hwang JH, Ljubenkov PA, Rojas JC, Rabinovici GD, Boxer AL, Seeley WW. PMID: 37725166; PMCID: PMC10564667.
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1 Fields:
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Humans
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Connectome-based modelling of neurodegenerative diseases: towards precision medicine and mechanistic insight. Nat Rev Neurosci. 2023 10; 24(10):620-639.
Vogel JW, Corriveau-Lecavalier N, Franzmeier N, Pereira JB, Brown JA, Maass A, Botha H, Seeley WW, Bassett DS, Jones DT, Ewers M. PMID: 37620599.
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3 Fields:
Translation:
Humans
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Network Connectivity Alterations across the MAPT Mutation Clinical Spectrum. Ann Neurol. 2023 10; 94(4):632-646.
Zhang L, Flagan TM, Häkkinen S, Chu SA, Brown JA, Lee AJ, Pasquini L, Mandelli ML, Gorno-Tempini ML, Sturm VE, Yokoyama JS, Appleby BS, Cobigo Y, Dickerson BC, Domoto-Reilly K, Geschwind DH, Ghoshal N, Graff-Radford NR, Grossman M, Hsiung GR, Huey ED, Kantarci K, Lario Lago A, Litvan I, Mackenzie IR, Mendez MF, Onyike CU, Ramos EM, Roberson ED, Tartaglia MC, Toga AW, Weintraub S, Wszolek ZK, Forsberg LK, Heuer HW, Boeve BF, Boxer AL, Rosen HJ, Miller BL, Seeley WW, Lee SE, ARTFL/LEFFTDS/ALLFTD Consortia. PMID: 37431188; PMCID: PMC10727479.
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Humans
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Frontotemporal lobar degeneration. Nat Rev Dis Primers. 2023 08 10; 9(1):40.
Grossman M, Seeley WW, Boxer AL, Hillis AE, Knopman DS, Ljubenov PA, Miller B, Piguet O, Rademakers R, Whitwell JL, Zetterberg H, van Swieten JC. PMID: 37563165.
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7 Fields:
Translation:
Humans
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Neuropsychiatric symptoms and imbalance of atrophy in behavioral variant frontotemporal dementia. Hum Brain Mapp. 2023 10 15; 44(15):5013-5029.
Sokolowski A, Roy ARK, Goh SM, Hardy EG, Datta S, Cobigo Y, Brown JA, Spina S, Grinberg L, Kramer J, Rankin KP, Seeley WW, Sturm VE, Rosen HJ, Miller BL, Perry DC. PMID: 37471695; PMCID: PMC10502637.
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2 Fields:
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Humans
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Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial tauopathy. Genome Med. 2023 07 18; 15(1):53.
Sirkis DW, Warly Solsberg C, Johnson TP, Bonham LW, Sturm VE, Lee SE, Rankin KP, Rosen HJ, Boxer AL, Seeley WW, Miller BL, Geier EG, Yokoyama JS. PMID: 37464408; PMCID: PMC10354988.
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HumansAnimalsCells
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Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. medRxiv. 2023 Jul 08.
Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, Lucio da Fonseca E, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Iqbal T, Pathak O, Valladares O, Kuzma AB, Abner E, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Goate AM, Grabowski TJ, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hall J, Hamilton RL, Harari O, Hardy J, Harrell LE, Head E, Henderson VW, Hernandez M, Hohman T, Honig LS, Huebinger RM, Huentelman MJ, Hulette CM, Hyman BT, Hynan LS, Ibanez L, Jarvik GP, Jayadev S, Jin LW, Johnson K, Johnson L, Kamboh MI, Karydas AM, Katz MJ, Kauwe JS, Kaye JA, Keene CD, Khaleeq A, Kim R, Knebl J, Kowall NW, Kramer JH, Kukull WA, LaFerla FM, Lah JJ, Larson EB, Lerner A, Leverenz JB, Levey AI, Lieberman AP, Lipton RB, Logue M, Lopez OL, Lunetta KL, Lyketsos CG, Mains D, Margaret FE, Marson DC, Martin ERR, Martiniuk F, Mash DC, Masliah E, Massman P, Masurkar A, McCormick WC, McCurry SM, McDavid AN, McDonough S, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Monuki ES, Morris JC, Mukherjee S, Myers AJ, Nguyen T, O'Bryant S, Olichney JM, Ory M, Palmer R, Parisi JE, Paulson HL, Pavlik V, Paydarfar D, Perez V, Peskind E, Petersen RC, Pierce A, Polk M, Poon WW, Potter H, Qu L, Quiceno M, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reisch JS, Ringman JM, Roberson ED, Rodriguear M, Rogaeva E, Rosen HJ, Rosenberg RN, Royall DR, Sager MA, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Slifer SH, Small S, Smith AG, Smith JP, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Stevens AB, Strittmatter SM, Sultzer D, Swerdlow RH, Tanzi RE, Tilson JL, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, van Eldik LJ, Vance JM, Vardarajan BN, Vassar R, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Whitehead PL, Wijsman EM, Wilhelmsen KC, Williams B, Williamson J, Wilms H, Wingo TS, Wisniewski T, Woltjer RL, Woon M, Wright CB, Wu CK, Younkin SG, Yu CE, Yu L, Zhu X, Kunkle BW, Bush WS, Wang LS, Farrer LA, Haines JL, et al. PMID: 37461624; PMCID: PMC10350126.
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A Precision Medicine Approach to Dementia Care: Syndrome, Etiology, and Copathology. Pract Neurol (Fort Wash Pa). 2023 Jul; 2023:17-22.
Fischer DL, Seeley WW. PMID: 37539046; PMCID: PMC10399644.
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KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss. bioRxiv. 2023 Jun 12.
Kauwe G, Pareja-Navarro KA, Yao L, Chen JH, Wong I, Saloner R, Cifuentes H, Nana AL, Shah S, Li Y, Le D, Spina S, Grinberg LT, Seeley WW, Kramer JH, Sacktor TC, Schilling B, Gan L, Casaletto KB, Tracy TE. PMID: 37398236; PMCID: PMC10312627.
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TMEM106B regulates microglial proliferation and survival in response to demyelination. Sci Adv. 2023 05 05; 9(18):eadd2676.
Zhang T, Pang W, Feng T, Guo J, Wu K, Nunez Santos M, Arthanarisami A, Nana AL, Nguyen Q, Kim PJ, Jankowsky JL, Seeley WW, Hu F. PMID: 37146150; PMCID: PMC10162677.
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6 Fields:
Translation:
HumansAnimalsCells
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Progranulin deficiency results in sex-dependent alterations in microglia in response to demyelination. Acta Neuropathol. 2023 07; 146(1):97-119.
Zhang T, Feng T, Wu K, Guo J, Nana AL, Yang G, Seeley WW, Hu F. PMID: 37120788; PMCID: PMC10375542.
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3 Fields:
Translation:
AnimalsCells
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Patients with sporadic FTLD exhibit similar increases in lysosomal proteins and storage material as patients with FTD due to GRN mutations. Acta Neuropathol Commun. 2023 04 28; 11(1):70.
Davis SE, Cook AK, Hall JA, Voskobiynyk Y, Carullo NV, Boyle NR, Hakim AR, Anderson KM, Hobdy KP, Pugh DA, Murchison CF, McMeekin LJ, Simmons M, Margolies KA, Cowell RM, Nana AL, Spina S, Grinberg LT, Miller BL, Seeley WW, Arrant AE. PMID: 37118844; PMCID: PMC10148425.
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1 Fields:
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Animals
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Creating the Pick's disease International Consortium: Association study of MAPT H2 haplotype with risk of Pick's disease. medRxiv. 2023 Apr 24.
Valentino RR, Scotton WJ, Roemer SF, Lashley T, Heckman MG, Shoai M, Martinez-Carrasco A, Tamvaka N, Walton RL, Baker MC, Macpherson HL, Real R, Soto-Beasley AI, Mok K, Revesz T, Warner TT, Jaunmuktane Z, Boeve BF, Christopher EA, DeTure M, Duara R, Graff-Radford NR, Josephs KA, Knopman DS, Koga S, Murray ME, Lyons KE, Pahwa R, Parisi JE, Petersen RC, Whitwell J, Grinberg LT, Miller B, Schlereth A, Seeley WW, Spina S, Grossman M, Irwin DJ, Lee EB, Suh E, Trojanowski JQ, Van Deerlin VM, Wolk DA, Connors TR, Dooley PM, Frosch MP, Oakley DH, Aldecoa I, Balasa M, Gelpi E, Borrego-Écija S, de Eugenio Huélamo RM, Gascon-Bayarri J, Sánchez-Valle R, Sanz-Cartagena P, Piñol-Ripoll G, Molina-Porcel L, Bigio EH, Flanagan ME, Gefen T, Rogalski EJ, Weintraub S, Redding-Ochoa J, Chang K, Troncoso JC, Prokop S, Newell KL, Ghetti B, Jones M, Richardson A, Robinson AC, Roncaroli F, Snowden J, Allinson K, Green O, Rowe JB, Singh P, Beach TG, Serrano GE, Flowers XE, Goldman JE, Heaps AC, Leskinen SP, Teich AF, Black SE, Keith JL, Masellis M, Bodi I, King A, Sarraj SA, Troakes C, Halliday GM, Hodges JR, Kril JJ, Kwok JB, Piguet O, Gearing M, Arzberger T, Roeber S, Attems J, Morris CM, Thomas AJ, Evers BM, White CL, Mechawar N, Sieben AA, Cras PP, De Vil BB, De Deyn PPPP, Duyckaerts C, Le Ber I, Seihean D, Turbant-Leclere S, MacKenzie IR, McLean C, Cykowski MD, Ervin JF, Wang SJ, Graff C, Nennesmo I, Nagra RM, Riehl J, Kovacs GG, Giaccone G, Nacmias B, Neumann M, Ang LC, Finger EC, Blauwendraat C, Nalls MA, Singleton AB, Vitale D, Cunha C, Carvalho A, Wszolek ZK, Morris HR, Rademakers R, Hardy JA, Dickson DW, Rohrer JD, Ross OA. PMID: 37163045; PMCID: PMC10168402.
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Progranulin inhibits phospholipase sPLA2-IIA to control neuroinflammation. bioRxiv. 2023 Apr 06.
Du H, Yang C, Nana AL, Seeley WW, Smolka M, Hu F. PMID: 37066328; PMCID: PMC10104136.
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Prevalence, Timing, and Network Localization of Emergent Visual Creativity in Frontotemporal Dementia. JAMA Neurol. 2023 04 01; 80(4):377-387.
Friedberg A, Pasquini L, Diggs R, Glaubitz EA, Lopez L, Illán-Gala I, Iaccarino L, La Joie R, Mundada N, Knudtson M, Neylan K, Brown J, Allen IE, Rankin KP, Bonham LW, Yokoyama JS, Ramos EM, Geschwind DH, Spina S, Grinberg LT, Miller ZA, Kramer JH, Rosen H, Gorno-Tempini ML, Rabinovici G, Seeley WW, Miller BL. PMID: 36848111; PMCID: PMC9972248.
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3 Fields:
Translation:
Humans
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Guam ALS-PDC is a distinct double-prion disorder featuring both tau and Aβ prions. Proc Natl Acad Sci U S A. 2023 03 28; 120(13):e2220984120.
Condello C, Ayers JI, Dalgard CL, Garcia Garcia MM, Rivera BM, Seeley WW, Perl DP, Prusiner SB. PMID: 36952379; PMCID: PMC10068802.
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2 Fields:
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Humans
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Astroglial toxicity promotes synaptic degeneration in the thalamocortical circuit in frontotemporal dementia with GRN mutations. J Clin Invest. 2023 03 15; 133(6).
Marsan E, Velmeshev D, Ramsey A, Patel RK, Zhang J, Koontz M, Andrews MG, de Majo M, Mora C, Blumenfeld J, Li AN, Spina S, Grinberg LT, Seeley WW, Miller BL, Ullian EM, Krummel MF, Kriegstein AR, Huang EJ. PMID: 36602862; PMCID: PMC10014110.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Long non-coding RNA SNHG8 drives stress granule formation in tauopathies. medRxiv. 2023 Mar 01.
Bhagat R, Minaya MA, Renganathan A, Mehra M, Marsh J, Martinez R, Nana AL, Spina S, Seeley WW, Grinberg LT, Karch CM. PMID: 36909621; PMCID: PMC10002771.
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Conserved gene signatures shared among MAPT mutations reveal defects in calcium signaling. Front Mol Biosci. 2023; 10:1051494.
Minaya MA, Mahali S, Iyer AK, Eteleeb AM, Martinez R, Huang G, Budde J, Temple S, Nana AL, Seeley WW, Spina S, Grinberg LT, Harari O, Karch CM. PMID: 36845551; PMCID: PMC9948093.
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1
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Alzheimer's disease phenotypes show different sleep architecture. Alzheimers Dement. 2023 08; 19(8):3272-3282.
Falgàs N, Walsh CM, Yack L, Simon AJ, Allen IE, Kramer JH, Rosen HJ, Joie R, Rabinovici G, Miller B, Spina S, Seeley WW, Ranasinghe K, Vossel K, Neylan TC, Grinberg LT. PMID: 36749893; PMCID: PMC10404632.
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3 Fields:
Translation:
Humans
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Three-Dimensional Imaging of Fibrinogen and Neurovascular Alterations in Alzheimer's Disease. Methods Mol Biol. 2023; 2561:87-101.
Merlini M, Sozmen EG, Subramanian KS, Nana AL, Seeley WW, Akassoglou K. PMID: 36399266.
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1 Fields:
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Humans
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Medial Temporal Lobe Tau Aggregation Relates to Divergent Cognitive and Emotional Empathy Abilities in Alzheimer's Disease. J Alzheimers Dis. 2023; 96(1):313-328.
Chow TE, Veziris CR, Mundada N, Martinez-Arroyo AI, Kramer JH, Miller BL, Rosen HJ, Gorno-Tempini ML, Rankin KP, Seeley WW, Rabinovici GD, La Joie R, Sturm VE. PMID: 37742643; PMCID: PMC10894587.
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Increasing empathic concern relates to salience network hyperconnectivity in cognitively healthy older adults with elevated amyloid-β burden. Neuroimage Clin. 2023; 37:103282.
Chow TE, Veziris CR, La Joie R, Lee AJ, Brown JA, Yokoyama JS, Rankin KP, Kramer JH, Miller BL, Rabinovici GD, Seeley WW, Sturm VE. PMID: 36525744; PMCID: PMC9758499.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Tuberous sclerosis complex is associated with a novel human tauopathy. Acta Neuropathol. 2023 01; 145(1):1-12.
Hwang JL, Perloff OS, Gaus SE, Benitez C, Alquezar C, Cosme CQ, Nana AL, Vatsavayai SC, Ramos EM, Geschwind DH, Miller BL, Kao AW, Seeley WW. PMID: 36469115; PMCID: PMC10244026.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Radiogenomics of C9orf72 Expansion Carriers Reveals Global Transposable Element Derepression and Enables Prediction of Thalamic Atrophy and Clinical Impairment. J Neurosci. 2023 01 11; 43(2):333-345.
Bonham LW, Geier EG, Sirkis DW, Leong JK, Ramos EM, Wang Q, Karydas A, Lee SE, Sturm VE, Sawyer RP, Friedberg A, Ichida JK, Gitler AD, Sugrue L, Cordingley M, Bee W, Weber E, Kramer JH, Rankin KP, Rosen HJ, Boxer AL, Seeley WW, Ravits J, Miller BL, Yokoyama JS. PMID: 36446586; PMCID: PMC9838702.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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CSF tau microtubule-binding region identifies pathological changes in primary tauopathies. Nat Med. 2022 12; 28(12):2547-2554.
Horie K, Barthélemy NR, Spina S, VandeVrede L, He Y, Paterson RW, Wright BA, Day GS, Davis AA, Karch CM, Seeley WW, Perrin RJ, Koppisetti RK, Shaikh F, Lago AL, Heuer HW, Ghoshal N, Gabelle A, Miller BL, Boxer AL, Bateman RJ, Sato C. PMID: 36424467; PMCID: PMC9800273.
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PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Right temporal degeneration and socioemotional semantics: semantic behavioural variant frontotemporal dementia. Brain. 2022 11 21; 145(11):4080-4096.
Younes K, Borghesani V, Montembeault M, Spina S, Mandelli ML, Welch AE, Weis E, Callahan P, Elahi FM, Hua AY, Perry DC, Karydas A, Geschwind D, Huang E, Grinberg LT, Kramer JH, Boxer AL, Rabinovici GD, Rosen HJ, Seeley WW, Miller ZA, Miller BL, Sturm VE, Rankin KP, Gorno-Tempini ML. PMID: 35731122; PMCID: PMC10200288.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Dynamic autonomic nervous system states arise during emotions and manifest in basal physiology. Psychophysiology. 2023 04; 60(4):e14218.
Pasquini L, Noohi F, Veziris CR, Kosik EL, Holley SR, Lee A, Brown JA, Roy ARK, Chow TE, Allen I, Rosen HJ, Kramer JH, Miller BL, Saggar M, Seeley WW, Sturm VE. PMID: 36371680; PMCID: PMC10038867.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Aβ and tau prions feature in the neuropathogenesis of Down syndrome. Proc Natl Acad Sci U S A. 2022 11 16; 119(46):e2212954119.
Condello C, Maxwell AM, Castillo E, Aoyagi A, Graff C, Ingelsson M, Lannfelt L, Bird TD, Keene CD, Seeley WW, Perl DP, Head E, Prusiner SB. PMID: 36343257; PMCID: PMC9674250.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis. Nat Commun. 2022 10 07; 13(1):5924.
Boland S, Swarup S, Ambaw YA, Malia PC, Richards RC, Fischer AW, Singh S, Aggarwal G, Spina S, Nana AL, Grinberg LT, Seeley WW, Surma MA, Klose C, Paulo JA, Nguyen AD, Harper JW, Walther TC, Farese RV. PMID: 36207292; PMCID: PMC9546883.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy. Mov Disord. 2022 10; 37(10):2110-2121.
Hopfner F, Tietz AK, Ruf VC, Ross OA, Koga S, Dickson D, Aguzzi A, Attems J, Beach T, Beller A, Cheshire WP, van Deerlin V, Desplats P, Deuschl G, Duyckaerts C, Ellinghaus D, Evsyukov V, Flanagan ME, Franke A, Frosch MP, Gearing M, Gelpi E, van Gerpen JA, Ghetti B, Glass JD, Grinberg LT, Halliday G, Helbig I, Höllerhage M, Huitinga I, Irwin DJ, Keene DC, Kovacs GG, Lee EB, Levin J, Martí MJ, Mackenzie I, McKeith I, Mclean C, Mollenhauer B, Neumann M, Newell KL, Pantelyat A, Pendziwiat M, Peters A, Molina Porcel L, Rabano A, Matej R, Rajput A, Rajput A, Reimann R, Scott WK, Seeley W, Selvackadunco S, Simuni T, Stadelmann C, Svenningsson P, Thomas A, Trenkwalder C, Troakes C, Trojanowski JQ, Uitti RJ, White CL, Wszolek ZK, Xie T, Ximelis T, Yebenes J, Alzheimer's Disease Genetics Consortium, Müller U, Schellenberg GD, Herms J, Kuhlenbäumer G, Höglinger G. PMID: 35997131; PMCID: PMC10052809.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Rainwater Charitable Foundation criteria for the neuropathologic diagnosis of progressive supranuclear palsy. Acta Neuropathol. 2022 10; 144(4):603-614.
Roemer SF, Grinberg LT, Crary JF, Seeley WW, McKee AC, Kovacs GG, Beach TG, Duyckaerts C, Ferrer IA, Gelpi E, Lee EB, Revesz T, White CL, Yoshida M, Pereira FL, Whitney K, Ghayal NB, Dickson DW. PMID: 35947184; PMCID: PMC9468104.
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PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Detection of emerging neurodegeneration using Bayesian linear mixed-effect modeling. Neuroimage Clin. 2022; 36:103144.
Cobigo Y, Goh MS, Wolf A, Staffaroni AM, Kornak J, Miller BL, Rabinovici GD, Seeley WW, Spina S, Boxer AL, Boeve BF, Wang L, Allegri R, Farlow M, Mori H, Perrin RJ, Kramer J, Rosen HJ, Alzheimer’s Disease Neuroimaging Initiative (ADNI) and the Dominantly Inherited Alzheimer’s Network . PMID: 36030718; PMCID: PMC9428846.
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Humans
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A dynamic gradient architecture generates brain activity states. Neuroimage. 2022 11 01; 261:119526.
Brown JA, Lee AJ, Pasquini L, Seeley WW. PMID: 35914669; PMCID: PMC9585924.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Postmortem Human Dura Mater Cells Exhibit Phenotypic, Transcriptomic and Genetic Abnormalities that Impact their Use for Disease Modeling. Stem Cell Rev Rep. 2022 12; 18(8):3050-3065.
Argouarch AR, Schultz N, Yang AC, Jang Y, Garcia K, Cosme CG, Corrales CI, Nana AL, Karydas AM, Spina S, Grinberg LT, Miller B, Wyss-Coray T, Abyzov A, Goodarzi H, Seeley WW, Kao AW. PMID: 35809166; PMCID: PMC9622518.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Enhanced positive emotional reactivity in frontotemporal dementia reflects left-lateralized atrophy in the temporal and frontal lobes. Cortex. 2022 09; 154:405-420.
Shdo SM, Roy ARK, Datta S, Sible IJ, Lukic S, Perry DC, Rankin KP, Kramer JH, Rosen HJ, Miller BL, Seeley WW, Holley SR, Gorno-Tempini ML, Sturm VE. PMID: 35930892; PMCID: PMC9867572.
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Translation:
Humans
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Default Mode Network quantitative diffusion and resting-state functional magnetic resonance imaging correlates in sporadic Creutzfeldt-Jakob disease. Hum Brain Mapp. 2022 09; 43(13):4158-4173.
Paoletti M, Caverzasi E, Mandelli ML, Brown JA, Henry RG, Miller BL, Rosen HJ, DeArmond SJ, Bastianello S, Seeley WW, Geschwind MD. PMID: 35662331; PMCID: PMC9374887.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Multi-Modal Biomarkers of Repetitive Head Impacts and Traumatic Encephalopathy Syndrome: A Clinicopathological Case Series. J Neurotrauma. 2022 09; 39(17-18):1195-1213.
Asken BM, Tanner JA, VandeVrede L, Casaletto KB, Staffaroni AM, Mundada N, Fonseca C, Iaccarino L, La Joie R, Tsuei T, Mladinov M, Grant H, Shankar R, Wang KKW, Xu H, Cobigo Y, Rosen H, Gardner RC, Perry DC, Miller BL, Spina S, Seeley WW, Kramer JH, Grinberg LT, Rabinovici GD. PMID: 35481808; PMCID: PMC9422800.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Automated Detection of Speech Timing Alterations in Autopsy-Confirmed Non-fluent/agrammatic Variant Primary Progressive Aphasia. Neurology. 2022 May 27.
García AM, Welch AE, Mandelli ML, Henry ML, Lukic S, Torres Prioris MJ, Deleon J, Ratnasiri BM, Lorca Puls DL, Miller BL, Seeley W, Vogel AP, Gorno-Tempini ML. PMID: 35623892.
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PubMed Mentions: Fields:
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Automated Detection of Speech Timing Alterations in Autopsy-Confirmed Nonfluent/Agrammatic Variant Primary Progressive Aphasia. Neurology. 2022 08 02; 99(5):e500-e511.
García AM, Welch AE, Mandelli ML, Henry ML, Lukic S, Torres Prioris MJ, Deleon J, Ratnasiri BM, Lorca-Puls DL, Miller BL, Seeley W, Vogel AP, Gorno-Tempini ML. PMID: 35914945; PMCID: PMC9421598.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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ZSCAN1 Autoantibodies Are Associated with Pediatric Paraneoplastic ROHHAD. Ann Neurol. 2022 08; 92(2):279-291.
Mandel-Brehm C, Benson LA, Tran B, Kung AF, Mann SA, Vazquez SE, Retallack H, Sample HA, Zorn KC, Khan LM, Kerr LM, McAlpine PL, Zhang L, McCarthy F, Elias JE, Katwa U, Astley CM, Tomko S, Dalmau J, Seeley WW, Pleasure SJ, Wilson MR, Gorman MP, DeRisi JL. PMID: 35466441; PMCID: PMC9329235.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Subcortical Neuronal Correlates of Sleep in Neurodegenerative Diseases. JAMA Neurol. 2022 05 01; 79(5):498-508.
Oh JY, Walsh CM, Ranasinghe K, Mladinov M, Pereira FL, Petersen C, Falgàs N, Yack L, Lamore T, Nasar R, Lew C, Li S, Metzler T, Coppola Q, Pandher N, Le M, Heuer HW, Heinsen H, Spina S, Seeley WW, Kramer J, Rabinovici GD, Boxer AL, Miller BL, Vossel K, Neylan TC, Grinberg LT. PMID: 35377391; PMCID: PMC8981071.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Regional Aβ-tau interactions promote onset and acceleration of Alzheimer's disease tau spreading. Neuron. 2022 06 15; 110(12):1932-1943.e5.
Lee WJ, Brown JA, Kim HR, La Joie R, Cho H, Lyoo CH, Rabinovici GD, Seong JK, Seeley WW, Alzheimer’s Disease Neuroimaging Initiative. PMID: 35443153; PMCID: PMC9233123.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy. Nat Commun. 2022 04 12; 13(1):1969.
Wang C, Fan L, Khawaja RR, Liu B, Zhan L, Kodama L, Chin M, Li Y, Le D, Zhou Y, Condello C, Grinberg LT, Seeley WW, Miller BL, Mok SA, Gestwicki JE, Cuervo AM, Luo W, Gan L. PMID: 35413950; PMCID: PMC9005658.
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PubMed Mentions:
66 Fields:
Translation:
AnimalsCells
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Diagnostic Accuracy of Magnetic Resonance Imaging Measures of Brain Atrophy Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Degeneration. JAMA Netw Open. 2022 04 01; 5(4):e229588.
Illán-Gala I, Nigro S, VandeVrede L, Falgàs N, Heuer HW, Painous C, Compta Y, Martí MJ, Montal V, Pagonabarraga J, Kulisevsky J, Lleó A, Fortea J, Logroscino G, Quattrone A, Quattrone A, Perry DC, Gorno-Tempini ML, Rosen HJ, Grinberg LT, Spina S, La Joie R, Rabinovici GD, Miller BL, Rojas JC, Seeley WW, Boxer AL. PMID: 35486397; PMCID: PMC9055455.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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The development and evolution of inhibitory neurons in primate cerebrum. Nature. 2022 03; 603(7903):871-877.
Schmitz MT, Sandoval K, Chen CP, Mostajo-Radji MA, Seeley WW, Nowakowski TJ, Ye CJ, Paredes MF, Pollen AA. PMID: 35322231; PMCID: PMC8967711.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A. Nature. 2022 03; 603(7899):124-130.
Ma XR, Prudencio M, Koike Y, Vatsavayai SC, Kim G, Harbinski F, Briner A, Rodriguez CM, Guo C, Akiyama T, Schmidt HB, Cummings BB, Wyatt DW, Kurylo K, Miller G, Mekhoubad S, Sallee N, Mekonnen G, Ganser L, Rubien JD, Jansen-West K, Cook CN, Pickles S, Oskarsson B, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Dickson DW, Shorter J, Myong S, Green EM, Seeley WW, Petrucelli L, Gitler AD. PMID: 35197626; PMCID: PMC8891019.
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PubMed Mentions:
120 Fields:
Translation:
HumansCells
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Cerebrospinal Fluid Biomarkers in Autopsy-Confirmed Alzheimer Disease and Frontotemporal Lobar Degeneration. Neurology. 2022 03 15; 98(11):e1137-e1150.
Mattsson-Carlgren N, Grinberg LT, Boxer A, Ossenkoppele R, Jonsson M, Seeley W, Ehrenberg A, Spina S, Janelidze S, Rojas-Martinex J, Rosen H, La Joie R, Lesman-Segev O, Iaccarino L, Kollmorgen G, Ljubenkov P, Eichenlaub U, Gorno-Tempini ML, Miller B, Hansson O, Rabinovici GD. PMID: 35173015; PMCID: PMC8935438.
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PubMed Mentions:
31 Fields:
Translation:
Humans
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Development of a standard of care for patients with valosin-containing protein associated multisystem proteinopathy. Orphanet J Rare Dis. 2022 01 29; 17(1):23.
Korb M, Peck A, Alfano LN, Berger KI, James MK, Ghoshal N, Healzer E, Henchcliffe C, Khan S, Mammen PPA, Patel S, Pfeffer G, Ralston SH, Roy B, Seeley WW, Swenson A, Mozaffar T, Weihl C, Kimonis V, VCP Standards of Care Working Group. PMID: 35093159; PMCID: PMC8800193.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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The behavioral variant of Alzheimer's disease does not show a selective loss of Von Economo and phylogenetically related neurons in the anterior cingulate cortex. Alzheimers Res Ther. 2022 01 20; 14(1):11.
Singleton EH, Pijnenburg YAL, Gami-Patel P, Boon BDC, Bouwman F, Papma JM, Seelaar H, Scheltens P, Grinberg LT, Spina S, Nana AL, Rabinovici GD, Seeley WW, Ossenkoppele R, Dijkstra AA. PMID: 35057846; PMCID: PMC8772094.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Influence of periaqueductal gray on other salience network nodes predicts social sensitivity. Hum Brain Mapp. 2022 04 01; 43(5):1694-1709.
Rijpma MG, Yang WFZ, Toller G, Battistella G, Sokolov AA, Sturm VE, Seeley WW, Kramer JH, Miller BL, Rankin KP. PMID: 34981605; PMCID: PMC8886662.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Research Criteria for the Behavioral Variant of Alzheimer Disease: A Systematic Review and Meta-analysis. JAMA Neurol. 2022 01 01; 79(1):48-60.
Ossenkoppele R, Singleton EH, Groot C, Dijkstra AA, Eikelboom WS, Seeley WW, Miller B, Laforce RJ, Scheltens P, Papma JM, Rabinovici GD, Pijnenburg YAL. PMID: 34870696; PMCID: PMC8649917.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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Late-Onset Alcohol Abuse as a Presenting Symptom of Neurodegenerative Diseases. J Alzheimers Dis. 2022; 86(3):1073-1080.
de Paula França Resende E, Ketelle R, Karydas A, Allen I, Grinberg LT, Spina S, Seeley WW, Perry DC, Miller B, Naasan G. PMID: 35180118; PMCID: PMC9090138.
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Humans
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The severity of neuropsychiatric symptoms is higher in early-onset than late-onset Alzheimer's disease. Eur J Neurol. 2022 04; 29(4):957-967.
Falgàs N, Allen IE, Spina S, Grant H, Piña Escudero SD, Merrilees J, Gearhart R, Rosen HJ, Kramer JH, Seeley WW, Neylan TC, Miller BL, Rabinovici GD, Grinberg LT, Walsh CM. PMID: 34862834; PMCID: PMC8901553.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease. Acta Neuropathol Commun. 2021 10 18; 9(1):169.
Rimal S, Li Y, Vartak R, Geng J, Tantray I, Li S, Huh S, Vogel H, Glabe C, Grinberg LT, Spina S, Seeley WW, Guo S, Lu B. PMID: 34663454; PMCID: PMC8522249.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic performance study. Lancet Neurol. 2021 09; 20(9):739-752.
Thijssen EH, La Joie R, Strom A, Fonseca C, Iaccarino L, Wolf A, Spina S, Allen IE, Cobigo Y, Heuer H, VandeVrede L, Proctor NK, Lago AL, Baker S, Sivasankaran R, Kieloch A, Kinhikar A, Yu L, Valentin MA, Jeromin A, Zetterberg H, Hansson O, Mattsson-Carlgren N, Graham D, Blennow K, Kramer JH, Grinberg LT, Seeley WW, Rosen H, Boeve BF, Miller BL, Teunissen CE, Rabinovici GD, Rojas JC, Dage JL, Boxer AL, Advancing Research and Treatment for Frontotemporal Lobar Degeneration investigators. PMID: 34418401; PMCID: PMC8711249.
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PubMed Mentions:
127 Fields:
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Comorbid neuropathological diagnoses in early versus late-onset Alzheimer's disease. Brain. 2021 08 17; 144(7):2186-2198.
Spina S, La Joie R, Petersen C, Nolan AL, Cuevas D, Cosme C, Hepker M, Hwang JH, Miller ZA, Huang EJ, Karydas AM, Grant H, Boxer AL, Gorno-Tempini ML, Rosen HJ, Kramer JH, Miller BL, Seeley WW, Rabinovici GD, Grinberg LT. PMID: 33693619; PMCID: PMC8502474.
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PubMed Mentions:
49 Fields:
Translation:
Humans
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Processing of progranulin into granulins involves multiple lysosomal proteases and is affected in frontotemporal lobar degeneration. Mol Neurodegener. 2021 08 03; 16(1):51.
Mohan S, Sampognaro PJ, Argouarch AR, Maynard JC, Welch M, Patwardhan A, Courtney EC, Zhang J, Mason A, Li KH, Huang EJ, Seeley WW, Miller BL, Burlingame A, Jacobson MP, Kao AW. PMID: 34344440; PMCID: PMC8330050.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Resting functional connectivity in the semantic appraisal network predicts accuracy of emotion identification. Neuroimage Clin. 2021; 31:102755.
Yang WFZ, Toller G, Shdo S, Kotz SA, Brown J, Seeley WW, Kramer JH, Miller BL, Rankin KP. PMID: 34274726; PMCID: PMC8319356.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Reduced synchrony in alpha oscillations during life predicts post mortem neurofibrillary tangle density in early-onset and atypical Alzheimer's disease. Alzheimers Dement. 2021 12; 17(12):2009-2019.
Ranasinghe KG, Petersen C, Kudo K, Mizuiri D, Rankin KP, Rabinovici GD, Gorno-Tempini ML, Seeley WW, Spina S, Miller BL, Vossel K, Grinberg LT, Nagarajan SS. PMID: 33884753; PMCID: PMC8528895.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Psychosis in neurodegenerative disease: differential patterns of hallucination and delusion symptoms. Brain. 2021 04 12; 144(3):999-1012.
Naasan G, Shdo SM, Rodriguez EM, Spina S, Grinberg L, Lopez L, Karydas A, Seeley WW, Miller BL, Rankin KP. PMID: 33501939; PMCID: PMC8041322.
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PubMed Mentions:
33 Fields:
Translation:
Humans
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Patterns of neuronal Rhes as a novel hallmark of tauopathies. Acta Neuropathol. 2021 05; 141(5):651-666.
Ehrenberg AJ, Leng K, Letourneau KN, Hernandez I, Lew C, Seeley WW, Spina S, Miller B, Heinsen H, Kampmann M, Kosik KS, Grinberg LT. PMID: 33677647; PMCID: PMC8418783.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Diagnostic Utility of Measuring Cerebral Atrophy in the Behavioral Variant of Frontotemporal Dementia and Association With Clinical Deterioration. JAMA Netw Open. 2021 03 01; 4(3):e211290.
Illán-Gala I, Falgàs N, Friedberg A, Castro-Suárez S, Keret O, Rogers N, Oz D, Nigro S, Quattrone A, Quattrone A, Wolf A, Younes K, Santos-Santos M, Borrego-Écija S, Cobigo Y, Dols-Icardo O, Lladó A, Sánchez-Valle R, Clarimon J, Blesa R, Alcolea D, Fortea J, Lleó A, Grinberg LT, Spina S, Kramer JH, Rabinovici GD, Boxer A, Gorno Tempini ML, Miller BL, Seeley WW, Rosen HJ, Perry DC. PMID: 33704477; PMCID: PMC7953307.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Sex differences in the behavioral variant of frontotemporal dementia: A new window to executive and behavioral reserve. Alzheimers Dement. 2021 08; 17(8):1329-1341.
Illán-Gala I, Casaletto KB, Borrego-Écija S, Arenaza-Urquijo EM, Wolf A, Cobigo Y, Goh SYM, Staffaroni AM, Alcolea D, Fortea J, Blesa R, Clarimon J, Iulita MF, Brugulat-Serrat A, Lladó A, Grinberg LT, Possin K, Rankin KP, Kramer JH, Rabinovici GD, Boxer A, Seeley WW, Sturm VE, Gorno-Tempini ML, Miller BL, Sánchez-Valle R, Perry DC, Lleó A, Rosen HJ. PMID: 33590953; PMCID: PMC8364861.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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A novel temporal-predominant neuro-astroglial tauopathy associated with TMEM106B gene polymorphism in FTLD/ALS-TDP. Brain Pathol. 2021 03; 31(2):267-282.
Llibre-Guerra JJ, Lee SE, Suemoto CK, Ehrenberg AJ, Kovacs GG, Karydas A, Staffaroni A, Franca Resende EP, Kim EJ, Hwang JH, Ramos EM, Wojta KJ, Pasquini L, Pang SY, Spina S, Allen IE, Kramer J, Miller BL, Seeley WW, Grinberg LT. PMID: 33314436; PMCID: PMC7946775.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Molecular characterization of selectively vulnerable neurons in Alzheimer's disease. Nat Neurosci. 2021 02; 24(2):276-287.
Leng K, Li E, Eser R, Piergies A, Sit R, Tan M, Neff N, Li SH, Rodriguez RD, Suemoto CK, Leite REP, Ehrenberg AJ, Pasqualucci CA, Seeley WW, Spina S, Heinsen H, Grinberg LT, Kampmann M. PMID: 33432193; PMCID: PMC7854528.
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PubMed Mentions:
150 Fields:
Translation:
HumansCells
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Diagnostic Accuracy of Amyloid versus 18 F-Fluorodeoxyglucose Positron Emission Tomography in Autopsy-Confirmed Dementia. Ann Neurol. 2021 02; 89(2):389-401.
Lesman-Segev OH, La Joie R, Iaccarino L, Lobach I, Rosen HJ, Seo SW, Janabi M, Baker SL, Edwards L, Pham J, Olichney J, Boxer A, Huang E, Gorno-Tempini M, DeCarli C, Hepker M, Hwang JL, Miller BL, Spina S, Grinberg LT, Seeley WW, Jagust WJ, Rabinovici GD. PMID: 33219525; PMCID: PMC7856004.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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18F-flortaucipir PET to autopsy comparisons in Alzheimer's disease and other neurodegenerative diseases. Brain. 2020 12 05; 143(11):3477-3494.
Soleimani-Meigooni DN, Iaccarino L, La Joie R, Baker S, Bourakova V, Boxer AL, Edwards L, Eser R, Gorno-Tempini ML, Jagust WJ, Janabi M, Kramer JH, Lesman-Segev OH, Mellinger T, Miller BL, Pham J, Rosen HJ, Spina S, Seeley WW, Strom A, Grinberg LT, Rabinovici GD. PMID: 33141172; PMCID: PMC7719031.
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PubMed Mentions:
64 Fields:
Translation:
HumansCells
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Brain volumetric deficits in MAPT mutation carriers: a multisite study. Ann Clin Transl Neurol. 2021 01; 8(1):95-110.
Chu SA, Flagan TM, Staffaroni AM, Jiskoot LC, Deng J, Spina S, Zhang L, Sturm VE, Yokoyama JS, Seeley WW, Papma JM, Geschwind DH, Rosen HJ, Boeve BF, Boxer AL, Heuer HW, Forsberg LK, Brushaber DE, Grossman M, Coppola G, Dickerson BC, Bordelon YM, Faber K, Feldman HH, Fields JA, Fong JC, Foroud T, Gavrilova RH, Ghoshal N, Graff-Radford NR, Hsiung GR, Huey ED, Irwin DJ, Kantarci K, Kaufer DI, Karydas AM, Knopman DS, Kornak J, Kramer JH, Kukull WA, Lapid MI, Litvan I, Mackenzie IRA, Mendez MF, Miller BL, Onyike CU, Pantelyat AY, Rademakers R, Marisa Ramos E, Roberson ED, Carmela Tartaglia M, Tatton NA, Toga AW, Vetor A, Weintraub S, Wong B, Wszolek ZK, ARTFL/LEFFTDS Consortium, Van Swieten JC, Lee SE. PMID: 33247623; PMCID: PMC7818091.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Tau Pathology Drives Dementia Risk-Associated Gene Networks toward Chronic Inflammatory States and Immunosuppression. Cell Rep. 2020 11 17; 33(7):108398.
Rexach JE, Polioudakis D, Yin A, Swarup V, Chang TS, Nguyen T, Sarkar A, Chen L, Huang J, Lin LC, Seeley W, Trojanowski JQ, Malhotra D, Geschwind DH. PMID: 33207193; PMCID: PMC7842189.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
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Elevated levels of extracellular vesicles in progranulin-deficient mice and FTD-GRN Patients. Ann Clin Transl Neurol. 2020 12; 7(12):2433-2449.
Arrant AE, Davis SE, Vollmer RM, Murchison CF, Mobley JA, Nana AL, Spina S, Grinberg LT, Karydas AM, Miller BL, Seeley WW, Roberson ED. PMID: 33197149; PMCID: PMC7732244.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Plasma Tau and Neurofilament Light in Frontotemporal Lobar Degeneration and Alzheimer Disease. Neurology. 2021 02 02; 96(5):e671-e683.
Illán-Gala I, Lleo A, Karydas A, Staffaroni AM, Zetterberg H, Sivasankaran R, Grinberg LT, Spina S, Kramer JH, Ramos EM, Coppola G, La Joie R, Rabinovici GD, Perry DC, Gorno-Tempini ML, Seeley WW, Miller BL, Rosen HJ, Blennow K, Boxer AL, Rojas JC. PMID: 33199433; PMCID: PMC7884995.
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PubMed Mentions:
48 Fields:
Translation:
Humans
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Investigating the clinico-anatomical dissociation in the behavioral variant of Alzheimer disease. Alzheimers Res Ther. 2020 11 14; 12(1):148.
Singleton EH, Pijnenburg YAL, Sudre CH, Groot C, Kochova E, Barkhof F, La Joie R, Rosen HJ, Seeley WW, Miller B, Cardoso MJ, Papma J, Scheltens P, Rabinovici GD, Ossenkoppele R. PMID: 33189136; PMCID: PMC7666520.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer's Disease. Cell. 2020 12 10; 183(6):1699-1713.e13.
Wesseling H, Mair W, Kumar M, Schlaffner CN, Tang S, Beerepoot P, Fatou B, Guise AJ, Cheng L, Takeda S, Muntel J, Rotunno MS, Dujardin S, Davies P, Kosik KS, Miller BL, Berretta S, Hedreen JC, Grinberg LT, Seeley WW, Hyman BT, Steen H, Steen JA. PMID: 33188775; PMCID: PMC8168922.
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PubMed Mentions:
209 Fields:
Translation:
HumansCells
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Salience Network Atrophy Links Neuron Type-Specific Pathobiology to Loss of Empathy in Frontotemporal Dementia. Cereb Cortex. 2020 09 03; 30(10):5387-5399.
Pasquini L, Nana AL, Toller G, Brown JA, Deng J, Staffaroni A, Kim EJ, Hwang JL, Li L, Park Y, Gaus SE, Allen I, Sturm VE, Spina S, Grinberg LT, Rankin KP, Kramer JH, Rosen HJ, Miller BL, Seeley WW. PMID: 32500143; PMCID: PMC7566683.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency. Nature. 2020 12; 588(7838):459-465.
Zhang J, Velmeshev D, Hashimoto K, Huang YH, Hofmann JW, Shi X, Chen J, Leidal AM, Dishart JG, Cahill MK, Kelley KW, Liddelow SA, Seeley WW, Miller BL, Walther TC, Farese RV, Taylor JP, Ullian EM, Huang B, Debnath J, Wittmann T, Kriegstein AR, Huang EJ. PMID: 32866962; PMCID: PMC7746606.
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PubMed Mentions:
64 Fields:
Translation:
AnimalsCells
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Positron Emission Tomography Imaging With [18F]flortaucipir and Postmortem Assessment of Alzheimer Disease Neuropathologic Changes. JAMA Neurol. 2020 07 01; 77(7):829-839.
Fleisher AS, Pontecorvo MJ, Devous MD, Lu M, Arora AK, Truocchio SP, Aldea P, Flitter M, Locascio T, Devine M, Siderowf A, Beach TG, Montine TJ, Serrano GE, Curtis C, Perrin A, Salloway S, Daniel M, Wellman C, Joshi AD, Irwin DJ, Lowe VJ, Seeley WW, Ikonomovic MD, Masdeu JC, Kennedy I, Harris T, Navitsky M, Southekal S, Mintun MA, A16 Study Investigators. PMID: 32338734; PMCID: PMC7186920.
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PubMed Mentions:
135 Fields:
Translation:
HumansCells
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Comparison of Amyloid in Cerebrospinal Fluid, Brain Imaging, and Autopsy in a Case of Progressive Supranuclear Palsy. Alzheimer Dis Assoc Disord. 2020 Jul-Sep; 34(3):275-277.
Kim KH, Seo JD, Kim ES, Kim HS, Jeon S, Pak K, Lee MJ, Lee JH, Lee YM, Lee K, Shin JH, Ko JK, Jung NY, Lee JM, Yoon JA, Hwang C, Ahn JW, Sung S, Spina S, Seeley WW, Choi KU, Huh GY, Kim EJ. PMID: 32520735.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Tau Positron Emission Tomographic Findings in a Former US Football Player With Pathologically Confirmed Chronic Traumatic Encephalopathy. JAMA Neurol. 2020 04 01; 77(4):517-521.
Mantyh WG, Spina S, Lee A, Iaccarino L, Soleimani-Meigooni D, Tsoy E, Mellinger TJ, Grant H, Vandevrede L, La Joie R, Lesman-Segev O, Gaus S, Possin KL, Grinberg LT, Miller BL, Seeley WW, Rabinovici GD. PMID: 31904765; PMCID: PMC6990867.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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Temporal variant of frontotemporal dementia in C9orf72 repeat expansion carriers: two case studies. Brain Imaging Behav. 2020 Apr; 14(2):336-345.
Caso F, Agosta F, Magnani G, Cardamone R, Borghesani V, Miller Z, Riva N, La Joie R, Coppola G, Grinberg LT, Seeley WW, Miller BL, Gorno-Tempini ML, Filippi M. PMID: 32180125; PMCID: PMC7467111.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Diagnostic value of plasma phosphorylated tau181 in Alzheimer's disease and frontotemporal lobar degeneration. Nat Med. 2020 03; 26(3):387-397.
Thijssen EH, La Joie R, Wolf A, Strom A, Wang P, Iaccarino L, Bourakova V, Cobigo Y, Heuer H, Spina S, VandeVrede L, Chai X, Proctor NK, Airey DC, Shcherbinin S, Duggan Evans C, Sims JR, Zetterberg H, Blennow K, Karydas AM, Teunissen CE, Kramer JH, Grinberg LT, Seeley WW, Rosen H, Boeve BF, Miller BL, Rabinovici GD, Dage JL, Rojas JC, Boxer AL, Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL) investigators. PMID: 32123386; PMCID: PMC7101073.
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PubMed Mentions:
284 Fields:
Translation:
HumansCells
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Language and spatial dysfunction in Alzheimer disease with white matter thorn-shaped astrocytes. Neurology. 2020 03 31; 94(13):e1353-e1364.
Resende EPF, Nolan AL, Petersen C, Ehrenberg AJ, Spina S, Allen IE, Rosen HJ, Kramer J, Miller BL, Seeley WW, Gorno-Tempini ML, Miller Z, Grinberg LT. PMID: 32001514; PMCID: PMC7274917.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Correction to: 4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration. Acta Neuropathol. 2020 Jan; 139(1):79-81.
Saijo E, Metrick MA, Koga S, Parchi P, Litvan I, Spina S, Boxer A, Rojas JC, Galasko D, Kraus A, Rossi M, Newell K, Zanusso G, Grinberg LT, Seeley WW, Ghetti B, Dickson DW, Caughey B. PMID: 31748840; PMCID: PMC7193369.
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PubMed Mentions:
2 Fields:
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Prospective longitudinal atrophy in Alzheimer's disease correlates with the intensity and topography of baseline tau-PET. Sci Transl Med. 2020 01 01; 12(524).
La Joie R, Visani AV, Baker SL, Brown JA, Bourakova V, Cha J, Chaudhary K, Edwards L, Iaccarino L, Janabi M, Lesman-Segev OH, Miller ZA, Perry DC, O'Neil JP, Pham J, Rojas JC, Rosen HJ, Seeley WW, Tsai RM, Miller BL, Jagust WJ, Rabinovici GD. PMID: 31894103; PMCID: PMC7035952.
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PubMed Mentions:
194 Fields:
Translation:
Humans
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Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations. Acta Neuropathol Commun. 2019 12 23; 7(1):218.
Arrant AE, Roth JR, Boyle NR, Kashyap SN, Hoffmann MQ, Murchison CF, Ramos EM, Nana AL, Spina S, Grinberg LT, Miller BL, Seeley WW, Roberson ED. PMID: 31870439; PMCID: PMC6929503.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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Task-Free Functional Language Networks: Reproducibility and Clinical Application. J Neurosci. 2020 02 05; 40(6):1311-1320.
Battistella G, Borghesani V, Henry M, Shwe W, Lauricella M, Miller Z, Deleon J, Miller BL, Dronkers N, Brambati SM, Seeley WW, Mandelli ML, Gorno-Tempini ML. PMID: 31852732; PMCID: PMC7002153.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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State and trait characteristics of anterior insula time-varying functional connectivity. Neuroimage. 2020 03; 208:116425.
Pasquini L, Toller G, Staffaroni A, Brown JA, Deng J, Lee A, Kurcyus K, Shdo SM, Allen I, Sturm VE, Cobigo Y, Borghesani V, Battistella G, Gorno-Tempini ML, Rankin KP, Kramer J, Rosen HH, Miller BL, Seeley WW. PMID: 31805382; PMCID: PMC7225015.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Astrocytic Tau Deposition Is Frequent in Typical and Atypical Alzheimer Disease Presentations. J Neuropathol Exp Neurol. 2019 12 01; 78(12):1112-1123.
Nolan A, De Paula Franca Resende E, Petersen C, Neylan K, Spina S, Huang E, Seeley W, Miller Z, Grinberg LT. PMID: 31626288; PMCID: PMC7967845.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Differences in neuroimaging features of early- versus late-onset nonfluent/agrammatic primary progressive aphasia. Neurobiol Aging. 2020 02; 86:92-101.
San Lee J, Yoo S, Park S, Kim HJ, Park KC, Seong JK, Suh MK, Lee J, Jang H, Kim KW, Kim Y, Cho SH, Kim SJ, Kim JP, Jung YH, Kim EJ, Suh YL, Lockhart SN, Seeley WW, Na DL, Seo SW. PMID: 31784276.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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The Salience Network: A Neural System for Perceiving and Responding to Homeostatic Demands. J Neurosci. 2019 12 11; 39(50):9878-9882.
Seeley WW. PMID: 31676604; PMCID: PMC6978945.
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PubMed Mentions:
183 Fields:
Translation:
HumansAnimals
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Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia. Brain Commun. 2019; 1(1):fcz027.
Miller ZA, Spina S, Pakvasa M, Rosenberg L, Watson C, Mandelli ML, Paredes MF, Joie R, Rabinovici GD, Rosen HJ, Grinberg LT, Huang EJ, Miller BL, Seeley WW, Gorno-Tempini ML. PMID: 32699834; PMCID: PMC7364264.
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PubMed Mentions:
6
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Preferential tau aggregation in von Economo neurons and fork cells in frontotemporal lobar degeneration with specific MAPT variants. Acta Neuropathol Commun. 2019 10 22; 7(1):159.
Lin LC, Nana AL, Hepker M, Hwang JL, Gaus SE, Spina S, Cosme CG, Gan L, Grinberg LT, Geschwind DH, Coppola G, Rosen HJ, Miller BL, Seeley WW. PMID: 31640778; PMCID: PMC6805408.
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PubMed Mentions:
21 Fields:
Translation:
HumansCells
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A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies. Stem Cell Reports. 2019 11 12; 13(5):939-955.
Karch CM, Kao AW, Karydas A, Onanuga K, Martinez R, Argouarch A, Wang C, Huang C, Sohn PD, Bowles KR, Spina S, Silva MC, Marsh JA, Hsu S, Pugh DA, Ghoshal N, Norton J, Huang Y, Lee SE, Seeley WW, Theofilas P, Grinberg LT, Moreno F, McIlroy K, Boeve BF, Cairns NJ, Crary JF, Haggarty SJ, Ichida JK, Kosik KS, Miller BL, Gan L, Goate AM, Temple S, Tau Consortium Stem Cell Group. PMID: 31631020; PMCID: PMC6895712.
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PubMed Mentions:
29 Fields:
Translation:
HumansCells
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C9orf72-specific phenomena associated with frontotemporal dementia and gastrointestinal symptoms in the absence of TDP-43 aggregation. Acta Neuropathol. 2019 12; 138(6):1093-1097.
Sampognaro PJ, Vatsavayai SC, Cosme CG, Hwang JL, Nolan A, Huang EJ, Seeley WW, De May MG. PMID: 31624869; PMCID: PMC6858587.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
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4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration. Acta Neuropathol. 2020 01; 139(1):63-77.
Saijo E, Metrick MA, Koga S, Parchi P, Litvan I, Spina S, Boxer A, Rojas JC, Galasko D, Kraus A, Rossi M, Newell K, Zanusso G, Grinberg LT, Seeley WW, Ghetti B, Dickson DW, Caughey B. PMID: 31616982; PMCID: PMC7192393.
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PubMed Mentions:
63 Fields:
Translation:
Humans
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Patient-Tailored, Connectivity-Based Forecasts of Spreading Brain Atrophy. Neuron. 2019 12 04; 104(5):856-868.e5.
Brown JA, Deng J, Neuhaus J, Sible IJ, Sias AC, Lee SE, Kornak J, Marx GA, Karydas AM, Spina S, Grinberg LT, Coppola G, Geschwind DH, Kramer JH, Gorno-Tempini ML, Miller BL, Rosen HJ, Seeley WW. PMID: 31623919; PMCID: PMC7012373.
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PubMed Mentions:
42 Fields:
Translation:
Humans
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Evidence of corticofugal tau spreading in patients with frontotemporal dementia. Acta Neuropathol. 2020 01; 139(1):27-43.
Kim EJ, Hwang JL, Gaus SE, Nana AL, Deng J, Brown JA, Spina S, Lee MJ, Ramos EM, Grinberg LT, Kramer JH, Boxer AL, Gorno-Tempini ML, Rosen HJ, Miller BL, Seeley WW. PMID: 31542807; PMCID: PMC7012377.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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Reply: LATE to the PART-y. Brain. 2019 09 01; 142(9):e48.
Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, Rademakers R, Alafuzoff I, Attems J, Brayne C, Coyle-Gilchrist ITS, Fardo DW, Flanagan ME, Halliday G, Hunter S, Jicha GA, Katsumata Y, Kawas CH, Keene CD, Kovacs GG, Kukull WA, Levey AI, Makkinejad N, Montine TJ, Murray ME, Nag S, Seeley WW, Sperling RA, White CL, Schneider JA. PMID: 31359039; PMCID: PMC6931389.
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PubMed Mentions:
9 Fields:
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Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nat Genet. 2019 Sep; 51(9):1423-1424.
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Uitterlinden AGA, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, et al. PMID: 31417202; PMCID: PMC7265117.
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PubMed Mentions:
28 Fields:
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THK5351 and flortaucipir PET with pathological correlation in a Creutzfeldt-Jakob disease patient: a case report. BMC Neurol. 2019 Aug 29; 19(1):211.
Kim HJ, Cho H, Park S, Jang H, Ryu YH, Choi JY, Moon SH, Oh SJ, Oh M, Na DL, Lyoo CH, Kim EJ, Seeley WW, Kim JS, Choi KC, Seo SW. PMID: 31464590; PMCID: PMC6714095.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Profound degeneration of wake-promoting neurons in Alzheimer's disease. Alzheimers Dement. 2019 10; 15(10):1253-1263.
Oh J, Eser RA, Ehrenberg AJ, Morales D, Petersen C, Kudlacek J, Dunlop SR, Theofilas P, Resende EDPF, Cosme C, Alho EJL, Spina S, Walsh CM, Miller BL, Seeley WW, Bittencourt JC, Neylan TC, Heinsen H, Grinberg LT. PMID: 31416793; PMCID: PMC6801040.
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PubMed Mentions:
41 Fields:
Translation:
HumansCells
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Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia. Sci Rep. 2019 07 26; 9(1):10854.
Bonham LW, Steele NZR, Karch CM, Broce I, Geier EG, Wen NL, Momeni P, Hardy J, Miller ZA, Gorno-Tempini ML, Hess CP, Lewis P, Miller BL, Seeley WW, Manzoni C, Desikan RS, Baranzini SE, Ferrari R, Yokoyama JS, International FTD-Genomics Consortium (IFGC). PMID: 31350420; PMCID: PMC6659677.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy. Acta Neuropathol. 2019 11; 138(5):795-811.
Cali CP, Patino M, Tai YK, Ho WY, McLean CA, Morris CM, Seeley WW, Miller BL, Gaig C, Vonsattel JPG, White CL, Roeber S, Kretzschmar H, Troncoso JC, Troakes C, Gearing M, Ghetti B, Van Deerlin VM, Lee VM, Trojanowski JQ, Mok KY, Ling H, Dickson DW, Schellenberg GD, Ling SC, Lee EB. PMID: 31327044; PMCID: PMC6802287.
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PubMed Mentions:
28 Fields:
Translation:
Humans
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Neuropathological correlates of structural and functional imaging biomarkers in 4-repeat tauopathies. Brain. 2019 07 01; 142(7):2068-2081.
Spina S, Brown JA, Deng J, Gardner RC, Nana AL, Hwang JL, Gaus SE, Huang EJ, Kramer JH, Rosen HJ, Kornak J, Neuhaus J, Miller BL, Grinberg LT, Boxer AL, Seeley WW. PMID: 31081015; PMCID: PMC6598736.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Alzheimer's disease clinical variants show distinct regional patterns of neurofibrillary tangle accumulation. Acta Neuropathol. 2019 10; 138(4):597-612.
Petersen C, Nolan AL, de Paula França Resende E, Miller Z, Ehrenberg AJ, Gorno-Tempini ML, Rosen HJ, Kramer JH, Spina S, Rabinovici GD, Miller BL, Seeley WW, Heinsen H, Grinberg LT. PMID: 31250152; PMCID: PMC7012374.
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PubMed Mentions:
47 Fields:
Translation:
HumansCells
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Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report. Brain. 2019 06 01; 142(6):1503-1527.
Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, Rademakers R, Alafuzoff I, Attems J, Brayne C, Coyle-Gilchrist ITS, Chui HC, Fardo DW, Flanagan ME, Halliday G, Hokkanen SRK, Hunter S, Jicha GA, Katsumata Y, Kawas CH, Keene CD, Kovacs GG, Kukull WA, Levey AI, Makkinejad N, Montine TJ, Murayama S, Murray ME, Nag S, Rissman RA, Seeley WW, Sperling RA, White CL, Yu L, Schneider JA. PMID: 31039256; PMCID: PMC6536849.
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PubMed Mentions:
507 Fields:
Translation:
Humans
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Early neuronal accumulation of DNA double strand breaks in Alzheimer's disease. Acta Neuropathol Commun. 2019 05 17; 7(1):77.
Shanbhag NM, Evans MD, Mao W, Nana AL, Seeley WW, Adame A, Rissman RA, Masliah E, Mucke L. PMID: 31101070; PMCID: PMC6524256.
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PubMed Mentions:
84 Fields:
Translation:
HumansAnimalsCells
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C9ORF72-ALS/FTD-associated poly(GR) binds Atp5a1 and compromises mitochondrial function in vivo. Nat Neurosci. 2019 06; 22(6):851-862.
Choi SY, Lopez-Gonzalez R, Krishnan G, Phillips HL, Li AN, Seeley WW, Yao WD, Almeida S, Gao FB. PMID: 31086314; PMCID: PMC6800116.
View in:
PubMed Mentions:
110 Fields:
Translation:
HumansAnimalsCells
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Tau covariance patterns in Alzheimer's disease patients match intrinsic connectivity networks in the healthy brain. Neuroimage Clin. 2019; 23:101848.
Ossenkoppele R, Iaccarino L, Schonhaut DR, Brown JA, La Joie R, O'Neil JP, Janabi M, Baker SL, Kramer JH, Gorno-Tempini ML, Miller BL, Rosen HJ, Seeley WW, Jagust WJ, Rabinovici GD. PMID: 31077982; PMCID: PMC6510968.
View in:
PubMed Mentions:
43 Fields:
Translation:
Humans
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Aβ and tau prion-like activities decline with longevity in the Alzheimer's disease human brain. Sci Transl Med. 2019 05 01; 11(490).
Aoyagi A, Condello C, Stöhr J, Yue W, Rivera BM, Lee JC, Woerman AL, Halliday G, van Duinen S, Ingelsson M, Lannfelt L, Graff C, Bird TD, Keene CD, Seeley WW, DeGrado WF, Prusiner SB. PMID: 31043574; PMCID: PMC6640844.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
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Corticobasal syndrome with visual hallucinations and probable REM-sleep behavior disorder: an autopsied case report of a patient with CBD and LBD pathology. Neurocase. 2019 Feb - Apr; 25(1-2):26-33.
Naasan G, Shany-Ur T, Sidhu M, Barton C, Ketelle R, Shdo SM, Kramer JH, Miller BL, Seeley WW. PMID: 31006355; PMCID: PMC7059557.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
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Dopamine receptor D4 (DRD4) polymorphisms with reduced functional potency intensify atrophy in syndrome-specific sites of frontotemporal dementia. Neuroimage Clin. 2019; 23:101822.
Butler PM, Chiong W, Perry DC, Miller ZA, Gennatas ED, Brown JA, Pasquini L, Karydas A, Dokuru D, Coppola G, Sturm VE, Boxer AL, Gorno-Tempini ML, Rosen HJ, Kramer JH, Miller BL, Seeley WW. PMID: 31003069; PMCID: PMC6475809.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Salience network connectivity is reduced by a meal and influenced by genetic background and hypothalamic gliosis. Int J Obes (Lond). 2020 01; 44(1):167-177.
Sewaybricker LE, Melhorn SJ, Askren MK, Webb MF, Tyagi V, De Leon MRB, Grabowski TJ, Seeley WW, Schur EA. PMID: 30967608; PMCID: PMC6785381.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
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Differential intrinsic functional connectivity changes in semantic variant primary progressive aphasia. Neuroimage Clin. 2019; 22:101797.
Battistella G, Henry M, Gesierich B, Wilson SM, Borghesani V, Shwe W, Miller Z, Deleon J, Miller BL, Jovicich J, Papinutto N, Dronkers NF, Seeley WW, Mandelli ML, Gorno-Tempini ML. PMID: 31146321; PMCID: PMC6465769.
View in:
PubMed Mentions:
25 Fields:
Translation:
Humans
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Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers. Neuroimage Clin. 2019; 22:101751.
Lee SE, Sias AC, Kosik EL, Flagan TM, Deng J, Chu SA, Brown JA, Vidovszky AA, Ramos EM, Gorno-Tempini ML, Karydas AM, Coppola G, Geschwind DH, Rademakers R, Boeve BF, Boxer AL, Rosen HJ, Miller BL, Seeley WW. PMID: 30921613; PMCID: PMC6438992.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nat Genet. 2019 03; 51(3):414-430.
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Andre Uitterlinden AG, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, et al. PMID: 30820047; PMCID: PMC6463297.
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PubMed Mentions:
1105 Fields:
Translation:
Humans
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Divergent patterns of loss of interpersonal warmth in frontotemporal dementia syndromes are predicted by altered intrinsic network connectivity. Neuroimage Clin. 2019; 22:101729.
Toller G, Yang WFZ, Brown JA, Ranasinghe KG, Shdo SM, Kramer JH, Seeley WW, Miller BL, Rankin KP. PMID: 30836325; PMCID: PMC6403437.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD. Acta Neuropathol. 2019 06; 137(6):879-899.
Pottier C, Ren Y, Perkerson RB, Baker M, Jenkins GD, van Blitterswijk M, DeJesus-Hernandez M, van Rooij JGJ, Murray ME, Christopher E, McDonnell SK, Fogarty Z, Batzler A, Tian S, Vicente CT, Matchett B, Karydas AM, Hsiung GR, Seelaar H, Mol MO, Finger EC, Graff C, Öijerstedt L, Neumann M, Heutink P, Synofzik M, Wilke C, Prudlo J, Rizzu P, Simon-Sanchez J, Edbauer D, Roeber S, Diehl-Schmid J, Evers BM, King A, Mesulam MM, Weintraub S, Geula C, Bieniek KF, Petrucelli L, Ahern GL, Reiman EM, Woodruff BK, Caselli RJ, Huey ED, Farlow MR, Grafman J, Mead S, Grinberg LT, Spina S, Grossman M, Irwin DJ, Lee EB, Suh E, Snowden J, Mann D, Ertekin-Taner N, Uitti RJ, Wszolek ZK, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Hodges JR, Piguet O, Geier EG, Yokoyama JS, Rissman RA, Rogaeva E, Keith J, Zinman L, Tartaglia MC, Cairns NJ, Cruchaga C, Ghetti B, Kofler J, Lopez OL, Beach TG, Arzberger T, Herms J, Honig LS, Vonsattel JP, Halliday GM, Kwok JB, White CL, Gearing M, Glass J, Rollinson S, Pickering-Brown S, Rohrer JD, Trojanowski JQ, Van Deerlin V, Bigio EH, Troakes C, Al-Sarraj S, Asmann Y, Miller BL, Graff-Radford NR, Boeve BF, Seeley WW, Mackenzie IRA, van Swieten JC, Dickson DW, Biernacka JM, Rademakers R. PMID: 30739198; PMCID: PMC6533145.
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PubMed Mentions:
54 Fields:
Translation:
HumansCells
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Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer's Disease Model. Neuron. 2019 03 20; 101(6):1099-1108.e6.
Merlini M, Rafalski VA, Rios Coronado PE, Gill TM, Ellisman M, Muthukumar G, Subramanian KS, Ryu JK, Syme CA, Davalos D, Seeley WW, Mucke L, Nelson RB, Akassoglou K. PMID: 30737131; PMCID: PMC6602536.
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PubMed Mentions:
142 Fields:
Translation:
HumansAnimalsCells
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Longitudinal multimodal imaging and clinical endpoints for frontotemporal dementia clinical trials. Brain. 2019 02 01; 142(2):443-459.
Staffaroni AM, Ljubenkov PA, Kornak J, Cobigo Y, Datta S, Marx G, Walters SM, Chiang K, Olney N, Elahi FM, Knopman DS, Dickerson BC, Boeve BF, Gorno-Tempini ML, Spina S, Grinberg LT, Seeley WW, Miller BL, Kramer JH, Boxer AL, Rosen HJ. PMID: 30698757; PMCID: PMC6351779.
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PubMed Mentions:
41 Fields:
Translation:
HumansCTClinical Trials
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Behavioral Variant Frontotemporal Dementia. Continuum (Minneap Minn). 2019 Feb; 25(1):76-100.
Seeley WW. PMID: 30707188.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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18F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes. Alzheimers Res Ther. 2019 01 31; 11(1):13.
Tsai RM, Bejanin A, Lesman-Segev O, LaJoie R, Visani A, Bourakova V, O'Neil JP, Janabi M, Baker S, Lee SE, Perry DC, Bajorek L, Karydas A, Spina S, Grinberg LT, Seeley WW, Ramos EM, Coppola G, Gorno-Tempini ML, Miller BL, Rosen HJ, Jagust W, Boxer AL, Rabinovici GD. PMID: 30704514; PMCID: PMC6357510.
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PubMed Mentions:
73 Fields:
Translation:
Humans
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Primary progressive aphasia and the FTD-MND spectrum disorders: clinical, pathological, and neuroimaging correlates. Amyotroph Lateral Scler Frontotemporal Degener. 2019 05; 20(3-4):146-158.
Vinceti G, Olney N, Mandelli ML, Spina S, Hubbard HI, Santos-Santos MA, Watson C, Miller ZA, Lomen-Hoerth C, Nichelli P, Miller BL, Grinberg LT, Seeley WW, Gorno-Tempini ML. PMID: 30668155; PMCID: PMC6759325.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Neurons selectively targeted in frontotemporal dementia reveal early stage TDP-43 pathobiology. Acta Neuropathol. 2019 01; 137(1):27-46.
Nana AL, Sidhu M, Gaus SE, Hwang JL, Li L, Park Y, Kim EJ, Pasquini L, Allen IE, Rankin KP, Toller G, Kramer JH, Geschwind DH, Coppola G, Huang EJ, Grinberg LT, Miller BL, Seeley WW. PMID: 30511086; PMCID: PMC6339592.
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PubMed Mentions:
59 Fields:
Translation:
HumansCells
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Intrinsic connectivity networks in posterior cortical atrophy: A role for the pulvinar? Neuroimage Clin. 2019; 21:101628.
Fredericks CA, Brown JA, Deng J, Kramer A, Ossenkoppele R, Rankin K, Kramer JH, Miller BL, Rabinovici GD, Seeley WW. PMID: 30528957; PMCID: PMC6411779.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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The Brain Donation Program in South Korea. Yonsei Med J. 2018 Dec; 59(10):1197-1204.
Kim Y, Suh YL, Kim SJ, Bae MH, Kim JB, Kim Y, Choi KC, Huh GY, Kim EJ, Lee JS, Kang HW, Shim SM, Lim HJ, Koh YH, Kim BC, Lee KH, Lee MC, Lee HW, Lim TS, Seeley WW, Kim HJ, Na DL, Lee KH, Seo SW. PMID: 30450854; PMCID: PMC6240560.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia. Ann Neurol. 2018 11; 84(5):729-740.
Bergeron D, Gorno-Tempini ML, Rabinovici GD, Santos-Santos MA, Seeley W, Miller BL, Pijnenburg Y, Keulen MA, Groot C, van Berckel BNM, van der Flier WM, Scheltens P, Rohrer JD, Warren JD, Schott JM, Fox NC, Sanchez-Valle R, Grau-Rivera O, Gelpi E, Seelaar H, Papma JM, van Swieten JC, Hodges JR, Leyton CE, Piguet O, Rogalski EJ, Mesulam MM, Koric L, Kristensen N, Pariente J, Dickerson B, Mackenzie IR, Hsiung GR, Belliard S, Irwin DJ, Wolk DA, Grossman M, Jones M, Harris J, Mann D, Snowden JS, Chrem-Mendez P, Calandri IL, Amengual AA, Miguet-Alfonsi C, Magnin E, Magnani G, Santangelo R, Deramecourt V, Pasquier F, Mattsson N, Nilsson C, Hansson O, Keith J, Masellis M, Black SE, Matías-Guiu JA, Cabrera-Martin MN, Paquet C, Dumurgier J, Teichmann M, Sarazin M, Bottlaender M, Dubois B, Rowe CC, Villemagne VL, Vandenberghe R, Granadillo E, Teng E, Mendez M, Meyer PT, Frings L, Lleó A, Blesa R, Fortea J, Seo SW, Diehl-Schmid J, Grimmer T, Frederiksen KS, Sánchez-Juan P, Chételat G, Jansen W, Bouchard RW, Laforce RJ, Visser PJ, Ossenkoppele R. PMID: 30255971; PMCID: PMC6354051.
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PubMed Mentions:
59 Fields:
Translation:
Humans
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Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia. Acta Neuropathol. 2019 01; 137(1):71-88.
Geier EG, Bourdenx M, Storm NJ, Cochran JN, Sirkis DW, Hwang JH, Bonham LW, Ramos EM, Diaz A, Van Berlo V, Dokuru D, Nana AL, Karydas A, Balestra ME, Huang Y, Russo SP, Spina S, Grinberg LT, Seeley WW, Myers RM, Miller BL, Coppola G, Lee SE, Cuervo AM, Yokoyama JS. PMID: 30382371; PMCID: PMC6371791.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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C9orf72-FTD/ALS pathogenesis: evidence from human neuropathological studies. Acta Neuropathol. 2019 01; 137(1):1-26.
Vatsavayai SC, Nana AL, Yokoyama JS, Seeley WW. PMID: 30368547; PMCID: PMC6546170.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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RNA Binding Proteins and the Pathogenesis of Frontotemporal Lobar Degeneration. Annu Rev Pathol. 2019 01 24; 14:469-495.
Hofmann JW, Seeley WW, Huang EJ. PMID: 30355151; PMCID: PMC6731550.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimals
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Multisite study of the relationships between antemortem [11C]PIB-PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology. Alzheimers Dement. 2019 02; 15(2):205-216.
La Joie R, Ayakta N, Seeley WW, Borys E, Boxer AL, DeCarli C, Doré V, Grinberg LT, Huang E, Hwang JH, Ikonomovic MD, Jack C, Jagust WJ, Jin LW, Klunk WE, Kofler J, Lesman-Segev OH, Lockhart SN, Lowe VJ, Masters CL, Mathis CA, McLean CL, Miller BL, Mungas D, O'Neil JP, Olichney JM, Parisi JE, Petersen RC, Rosen HJ, Rowe CC, Spina S, Vemuri P, Villemagne VL, Murray ME, Rabinovici GD. PMID: 30347188; PMCID: PMC6368897.
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PubMed Mentions:
97 Fields:
Translation:
Humans
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Subcellular organization of UBE3A in human cerebral cortex. Mol Autism. 2018; 9:54.
Burette AC, Judson MC, Li AN, Chang EF, Seeley WW, Philpot BD, Weinberg RJ. PMID: 30364390; PMCID: PMC6194692.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Distinctive Structural and Molecular Features of Myelinated Inhibitory Axons in Human Neocortex. eNeuro. 2018 Sep-Oct; 5(5).
Micheva KD, Chang EF, Nana AL, Seeley WW, Ting JT, Cobbs C, Lein E, Smith SJ, Weinberg RJ, Madison DV. PMID: 30406183; PMCID: PMC6220577.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Mixed TDP-43 proteinopathy and tauopathy in frontotemporal lobar degeneration: nine case series. J Neurol. 2018 Dec; 265(12):2960-2971.
Kim EJ, Brown JA, Deng J, Hwang JL, Spina S, Miller ZA, DeMay MG, Valcour V, Karydas A, Ramos EM, Coppola G, Miller BL, Rosen HJ, Seeley WW, Grinberg LT. PMID: 30324308; PMCID: PMC6245666.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers. Brain. 2018 10 01; 141(10):2895-2907.
Zhang M, Ferrari R, Tartaglia MC, Keith J, Surace EI, Wolf U, Sato C, Grinberg M, Liang Y, Xi Z, Dupont K, McGoldrick P, Weichert A, McKeever PM, Schneider R, McCorkindale MD, Manzoni C, Rademakers R, Graff-Radford NR, Dickson DW, Parisi JE, Boeve BF, Petersen RC, Miller BL, Seeley WW, van Swieten JC, van Rooij J, Pijnenburg Y, van der Zee J, Van Broeckhoven C, Le Ber I, Van Deerlin V, Suh E, Rohrer JD, Mead S, Graff C, Öijerstedt L, Pickering-Brown S, Rollinson S, Rossi G, Tagliavini F, Brooks WS, Dobson-Stone C, Halliday GM, Hodges JR, Piguet O, Binetti G, Benussi L, Ghidoni R, Nacmias B, Sorbi S, Bruni AC, Galimberti D, Scarpini E, Rainero I, Rubino E, Clarimon J, Lleó A, Ruiz A, Hernández I, Pastor P, Diez-Fairen M, Borroni B, Pasquier F, Deramecourt V, Lebouvier T, Perneczky R, Diehl-Schmid J, Grafman J, Huey ED, Mayeux R, Nalls MA, Hernandez D, Singleton A, Momeni P, Zeng Z, Hardy J, Robertson J, Zinman L, Rogaeva E, International FTD-Genomics Consortium (IFGC). PMID: 30252044; PMCID: PMC6158742.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Protein network analysis reveals selectively vulnerable regions and biological processes in FTD. Neurol Genet. 2018 Oct; 4(5):e266.
Bonham LW, Steele NZR, Karch CM, Manzoni C, Geier EG, Wen N, Ofori-Kuragu A, Momeni P, Hardy J, Miller ZA, Hess CP, Lewis P, Miller BL, Seeley WW, Baranzini SE, Desikan RS, Ferrari R, Yokoyama JS, International FTD-Genomics Consortium (IFGC). PMID: 30283816; PMCID: PMC6167176.
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PubMed Mentions:
7
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Cerebrospinal fluid biomarkers predict frontotemporal dementia trajectory. Ann Clin Transl Neurol. 2018 Oct; 5(10):1250-1263.
Ljubenkov PA, Staffaroni AM, Rojas JC, Allen IE, Wang P, Heuer H, Karydas A, Kornak J, Cobigo Y, Seeley WW, Grinberg LT, Spina S, Fagan AM, Jerome G, Knopman D, Boeve BF, Dickerson BC, Kramer J, Miller B, Boxer AL, Rosen HJ. PMID: 30349860; PMCID: PMC6186942.
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PubMed Mentions:
25 Fields:
-
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
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Network Architecture Underlying Basal Autonomic Outflow: Evidence from Frontotemporal Dementia. J Neurosci. 2018 10 17; 38(42):8943-8955.
Sturm VE, Brown JA, Hua AY, Lwi SJ, Zhou J, Kurth F, Eickhoff SB, Rosen HJ, Kramer JH, Miller BL, Levenson RW, Seeley WW. PMID: 30181137; PMCID: PMC6191520.
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PubMed Mentions:
33 Fields:
Translation:
Humans
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Altered topology of the functional speech production network in non-fluent/agrammatic variant of PPA. Cortex. 2018 11; 108:252-264.
Mandelli ML, Welch AE, Vilaplana E, Watson C, Battistella G, Brown JA, Possin KL, Hubbard HI, Miller ZA, Henry ML, Marx GA, Santos-Santos MA, Bajorek LP, Fortea J, Boxer A, Rabinovici G, Lee S, Deleon J, Rosen HJ, Miller BL, Seeley WW, Gorno-Tempini ML. PMID: 30292076; PMCID: PMC6317366.
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PubMed Mentions:
27 Fields:
Translation:
Humans
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Early affective changes and increased connectivity in preclinical Alzheimer's disease. Alzheimers Dement (Amst). 2018; 10:471-479.
Fredericks CA, Sturm VE, Brown JA, Hua AY, Bilgel M, Wong DF, Resnick SM, Seeley WW. PMID: 30302368; PMCID: PMC6174255.
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PubMed Mentions:
22
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Prevalence of Mathematical and Visuospatial Learning Disabilities in Patients With Posterior Cortical Atrophy. JAMA Neurol. 2018 06 01; 75(6):728-737.
Miller ZA, Rosenberg L, Santos-Santos MA, Stephens M, Allen IE, Hubbard HI, Cantwell A, Mandelli ML, Grinberg LT, Seeley WW, Miller BL, Rabinovici GD, Gorno-Tempini ML. PMID: 29630699; PMCID: PMC6027634.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. Lancet Neurol. 2018 06; 17(6):548-558.
Pottier C, Zhou X, Perkerson RB, Baker M, Jenkins GD, Serie DJ, Ghidoni R, Benussi L, Binetti G, López de Munain A, Zulaica M, Moreno F, Le Ber I, Pasquier F, Hannequin D, Sánchez-Valle R, Antonell A, Lladó A, Parsons TM, Finch NA, Finger EC, Lippa CF, Huey ED, Neumann M, Heutink P, Synofzik M, Wilke C, Rissman RA, Slawek J, Sitek E, Johannsen P, Nielsen JE, Ren Y, van Blitterswijk M, DeJesus-Hernandez M, Christopher E, Murray ME, Bieniek KF, Evers BM, Ferrari C, Rollinson S, Richardson A, Scarpini E, Fumagalli GG, Padovani A, Hardy J, Momeni P, Ferrari R, Frangipane F, Maletta R, Anfossi M, Gallo M, Petrucelli L, Suh E, Lopez OL, Wong TH, van Rooij JGJ, Seelaar H, Mead S, Caselli RJ, Reiman EM, Noel Sabbagh M, Kjolby M, Nykjaer A, Karydas AM, Boxer AL, Grinberg LT, Grafman J, Spina S, Oblak A, Mesulam MM, Weintraub S, Geula C, Hodges JR, Piguet O, Brooks WS, Irwin DJ, Trojanowski JQ, Lee EB, Josephs KA, Parisi JE, Ertekin-Taner N, Knopman DS, Nacmias B, Piaceri I, Bagnoli S, Sorbi S, Gearing M, Glass J, Beach TG, Black SE, Masellis M, Rogaeva E, Vonsattel JP, Honig LS, Kofler J, Bruni AC, Snowden J, Mann D, Pickering-Brown S, Diehl-Schmid J, Winkelmann J, Galimberti D, Graff C, Öijerstedt L, Troakes C, Al-Sarraj S, Cruchaga C, Cairns NJ, Rohrer JD, Halliday GM, Kwok JB, van Swieten JC, White CL, Ghetti B, Murell JR, Mackenzie IRA, Hsiung GR, Borroni B, Rossi G, Tagliavini F, Wszolek ZK, Petersen RC, Bigio EH, Grossman M, Van Deerlin VM, Seeley WW, Miller BL, Graff-Radford NR, Boeve BF, Dickson DW, Biernacka JM, Rademakers R. PMID: 29724592; PMCID: PMC6237181.
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PubMed Mentions:
58 Fields:
Translation:
Humans
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Physiological changes in neurodegeneration - mechanistic insights and clinical utility. Nat Rev Neurol. 2018 05; 14(5):259-271.
Ahmed RM, Ke YD, Vucic S, Ittner LM, Seeley W, Hodges JR, Piguet O, Halliday G, Kiernan MC. PMID: 29569624.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimals
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Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia. JAMA Neurol. 2018 03 01; 75(3):342-352.
Santos-Santos MA, Rabinovici GD, Iaccarino L, Ayakta N, Tammewar G, Lobach I, Henry ML, Hubbard I, Mandelli ML, Spinelli E, Miller ZA, Pressman PS, O'Neil JP, Ghosh P, Lazaris A, Meyer M, Watson C, Yoon SJ, Rosen HJ, Grinberg L, Seeley WW, Miller BL, Jagust WJ, Gorno-Tempini ML. PMID: 29309493; PMCID: PMC5885868.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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Individual differences in socioemotional sensitivity are an index of salience network function. Cortex. 2018 06; 103:211-223.
Toller G, Brown J, Sollberger M, Shdo SM, Bouvet L, Sukhanov P, Seeley WW, Miller BL, Rankin KP. PMID: 29656245; PMCID: PMC6143366.
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PubMed Mentions:
39 Fields:
Translation:
Humans
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Early vs late age at onset frontotemporal dementia and frontotemporal lobar degeneration. Neurology. 2018 03 20; 90(12):e1047-e1056.
Seo SW, Thibodeau MP, Perry DC, Hua A, Sidhu M, Sible I, Vargas JNS, Gaus SE, Rabinovici GD, Rankin KD, Boxer AL, Kramer JH, Rosen HJ, Gorno-Tempini ML, Grinberg LT, Huang EJ, DeArmond SJ, Trojanowski JQ, Miller BL, Seeley WW. PMID: 29453245; PMCID: PMC5874448.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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The Longitudinal Trajectory of Default Mode Network Connectivity in Healthy Older Adults Varies As a Function of Age and Is Associated with Changes in Episodic Memory and Processing Speed. J Neurosci. 2018 03 14; 38(11):2809-2817.
Staffaroni AM, Brown JA, Casaletto KB, Elahi FM, Deng J, Neuhaus J, Cobigo Y, Mumford PS, Walters S, Saloner R, Karydas A, Coppola G, Rosen HJ, Miller BL, Seeley WW, Kramer JH. PMID: 29440553; PMCID: PMC5852659.
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PubMed Mentions:
92 Fields:
Translation:
Humans
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Selective Vulnerability of Brainstem Nuclei in Distinct Tauopathies: A Postmortem Study. J Neuropathol Exp Neurol. 2018 02 01; 77(2):149-161.
Eser RA, Ehrenberg AJ, Petersen C, Dunlop S, Mejia MB, Suemoto CK, Walsh CM, Rajana H, Oh J, Theofilas P, Seeley WW, Miller BL, Neylan TC, Heinsen H, Grinberg LT. PMID: 29304218; PMCID: PMC6251636.
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PubMed Mentions:
29 Fields:
Translation:
Humans
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PubMed Mentions: Fields:
Translation:
Humans
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Von Economo Neurons and Fork Cells: A Neurochemical Signature Linked to Monoaminergic Function. Cereb Cortex. 2018 01 01; 28(1):131-144.
Dijkstra AA, Lin LC, Nana AL, Gaus SE, Seeley WW. PMID: 27913432; PMCID: PMC6075576.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Reward deficits in behavioural variant frontotemporal dementia include insensitivity to negative stimuli. Brain. 2017 Dec 01; 140(12):3346-3356.
Perry DC, Datta S, Sturm VE, Wood KA, Zakrzewski J, Seeley WW, Miller BL, Kramer JH, Rosen HJ. PMID: 29053832; PMCID: PMC5841034.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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Clinicopathological correlations in behavioural variant frontotemporal dementia. Brain. 2017 Dec 01; 140(12):3329-3345.
Perry DC, Brown JA, Possin KL, Datta S, Trujillo A, Radke A, Karydas A, Kornak J, Sias AC, Rabinovici GD, Gorno-Tempini ML, Boxer AL, De May M, Rankin KP, Sturm VE, Lee SE, Matthews BR, Kao AW, Vossel KA, Tartaglia MC, Miller ZA, Seo SW, Sidhu M, Gaus SE, Nana AL, Vargas JNS, Hwang JL, Ossenkoppele R, Brown AB, Huang EJ, Coppola G, Rosen HJ, Geschwind D, Trojanowski JQ, Grinberg LT, Kramer JH, Miller BL, Seeley WW. PMID: 29053860; PMCID: PMC5841140.
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PubMed Mentions:
119 Fields:
Translation:
Humans
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Alzheimer's Disease-Related Dementias Summit 2016: National research priorities. Neurology. 2017 Dec 05; 89(23):2381-2391.
Corriveau RA, Koroshetz WJ, Gladman JT, Jeon S, Babcock D, Bennett DA, Carmichael ST, Dickinson SL, Dickson DW, Emr M, Fillit H, Greenberg SM, Hutton ML, Knopman DS, Manly JJ, Marder KS, Moy CS, Phelps CH, Scott PA, Seeley WW, Sieber BA, Silverberg NB, Sutherland ML, Taylor A, Torborg CL, Waddy SP, Gubitz AK, Holtzman DM. PMID: 29117955; PMCID: PMC5719928.
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PubMed Mentions:
75 Fields:
Translation:
Humans
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18 F-flortaucipir tau positron emission tomography distinguishes established progressive supranuclear palsy from controls and Parkinson disease: A multicenter study. Ann Neurol. 2017 Oct; 82(4):622-634.
Schonhaut DR, McMillan CT, Spina S, Dickerson BC, Siderowf A, Devous MD, Tsai R, Winer J, Russell DS, Litvan I, Roberson ED, Seeley WW, Grinberg LT, Kramer JH, Miller BL, Pressman P, Nasrallah I, Baker SL, Gomperts SN, Johnson KA, Grossman M, Jagust WJ, Boxer AL, Rabinovici GD. PMID: 28980714; PMCID: PMC5665658.
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PubMed Mentions:
83 Fields:
Translation:
Humans
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Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer's disease Braak stages: a quantitative study in humans. Neurobiol Aging. 2018 01; 61:1-12.
Theofilas P, Ehrenberg AJ, Nguy A, Thackrey JM, Dunlop S, Mejia MB, Alho AT, Paraizo Leite RE, Rodriguez RD, Suemoto CK, Nascimento CF, Chin M, Medina-Cleghorn D, Cuervo AM, Arkin M, Seeley WW, Miller BL, Nitrini R, Pasqualucci CA, Filho WJ, Rueb U, Neuhaus J, Heinsen H, Grinberg LT. PMID: 29031088; PMCID: PMC5705284.
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PubMed Mentions:
46 Fields:
Translation:
HumansCells
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ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy. Nature. 2017 09 28; 549(7673):523-527.
Shi Y, Yamada K, Liddelow SA, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC, Gallardo G, Wang K, Roh J, Robinson G, Finn MB, Jiang H, Sullivan PM, Baufeld C, Wood MW, Sutphen C, McCue L, Xiong C, Del-Aguila JL, Morris JC, Cruchaga C, Alzheimer’s Disease Neuroimaging Initiative, Fagan AM, Miller BL, Boxer AL, Seeley WW, Butovsky O, Barres BA, Paul SM, Holtzman DM. PMID: 28959956; PMCID: PMC5641217.
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PubMed Mentions:
519 Fields:
Translation:
HumansAnimalsCells
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Advancing functional dysconnectivity and atrophy in progressive supranuclear palsy. Neuroimage Clin. 2017; 16:564-574.
Brown JA, Hua AY, Trujllo A, Attygalle S, Binney RJ, Spina S, Lee SE, Kramer JH, Miller BL, Rosen HJ, Boxer AL, Seeley WW. PMID: 28951832; PMCID: PMC5605489.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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An 8-week, open-label, dose-finding study of nimodipine for the treatment of progranulin insufficiency from GRN gene mutations. Alzheimers Dement (N Y). 2017 Nov; 3(4):507-512.
Sha SJ, Miller ZA, Min SW, Zhou Y, Brown J, Mitic LL, Karydas A, Koestler M, Tsai R, Corbetta-Rastelli C, Lin S, Hare E, Fields S, Fleischmann KE, Powers R, Fitch R, Martens LH, Shamloo M, Fagan AM, Farese RV, Pearlman R, Seeley W, Miller BL, Gan L, Boxer AL. PMID: 29124108; PMCID: PMC5671622.
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PubMed Mentions:
16
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Globular glial tauopathy presenting as non-fluent/agrammatic variant primary progressive aphasia with chorea. Parkinsonism Relat Disord. 2017 11; 44:159-161.
Kim EJ, Lee MJ, Lee JH, Lee YM, Shin JH, Shin MJ, Choi KU, Jung NY, Pak K, Hwang C, Ahn JW, Sung S, Spina S, Grinberg LT, Seeley WW, Huh GY. PMID: 28923295; PMCID: PMC5899893.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Erratum to: Interhemispheric gene expression differences in the cerebral cortex of humans and macaque monkeys. Brain Struct Funct. 2017 09; 222(7):3367-3368.
Muntané G, Santpere G, Verendeev A, Seeley WW, Jacobs B, Hopkins WD, Navarro A, Sherwood CC. PMID: 28488187.
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PubMed Mentions: Fields:
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Linking tuberous sclerosis complex, excessive mTOR signaling, and age-related neurodegeneration: a new association between TSC1 mutation and frontotemporal dementia. Acta Neuropathol. 2017 11; 134(5):813-816.
Olney NT, Alquezar C, Ramos EM, Nana AL, Fong JC, Karydas AM, Taylor JB, Stephens ML, Argouarch AR, Van Berlo VA, Dokuru DR, Sherr EH, Jicha GA, Dillon WP, Desikan RS, De May M, Seeley WW, Coppola G, Miller BL, Kao AW. PMID: 28828560; PMCID: PMC5645431.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Mapping Neurodegenerative Disease Onset and Progression. Cold Spring Harb Perspect Biol. 2017 Aug 01; 9(8).
Seeley WW. PMID: 28289062; PMCID: PMC5538416.
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PubMed Mentions:
44 Fields:
Translation:
Humans
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Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nat Genet. 2017 09; 49(9):1373-1384.
Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, Leber M, Chen Y, Albert MS, Riedel-Heller S, Emilsson V, Beekly D, Braae A, Schmidt R, Blacker D, Masullo C, Schmidt H, Doody RS, Spalletta G, Longstreth WT, Fairchild TJ, Bossù P, Lopez OL, Frosch MP, Sacchinelli E, Ghetti B, Yang Q, Huebinger RM, Jessen F, Li S, Kamboh MI, Morris J, Sotolongo-Grau O, Katz MJ, Corcoran C, Dunstan M, Braddel A, Thomas C, Meggy A, Marshall R, Gerrish A, Chapman J, Aguilar M, Taylor S, Hill M, Fairén MD, Hodges A, Vellas B, Soininen H, Kloszewska I, Daniilidou M, Uphill J, Patel Y, Hughes JT, Lord J, Turton J, Hartmann AM, Cecchetti R, Fenoglio C, Serpente M, Arcaro M, Caltagirone C, Orfei MD, Ciaramella A, Pichler S, Mayhaus M, Gu W, Lleó A, Fortea J, Blesa R, Barber IS, Brookes K, Cupidi C, Maletta RG, Carrell D, Sorbi S, Moebus S, Urbano M, Pilotto A, Kornhuber J, Bosco P, Todd S, Craig D, Johnston J, Gill M, Lawlor B, Lynch A, Fox NC, Hardy J, ARUK Consortium, Albin RL, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Baldwin CT, Barnes LL, Barral S, Beach TG, Becker JT, Bigio EH, Bird TD, Boeve BF, Bowen JD, Boxer A, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Carroll SL, Diaz CC, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, Dick M, Duara R, Evans DA, Faber KM, Fallon KB, Fardo DW, Farlow MR, Ferris S, Foroud TM, Galasko DR, Gearing M, Geschwind DH, Gilbert JR, Graff-Radford NR, Green RC, Growdon JH, Hamilton RL, Harrell LE, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Abner E, Jin LW, Jun G, Karydas A, Kaye JA, Kim R, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lunetta KL, Lyketsos CG, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Morris JC, Murrell JR, Myers AJ, O'Bryant S, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Perry W, Peskind E, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, et al. PMID: 28714976; PMCID: PMC5669039.
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PubMed Mentions:
459 Fields:
Translation:
HumansCells
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Genetic screening in sporadic ALS and FTD. J Neurol Neurosurg Psychiatry. 2017 12; 88(12):1042-1044.
Turner MR, Al-Chalabi A, Chio A, Hardiman O, Kiernan MC, Rohrer JD, Rowe J, Seeley W, Talbot K. PMID: 28642287; PMCID: PMC5740553.
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PubMed Mentions:
62 Fields:
Translation:
Humans
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Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutations. Nat Commun. 2017 05 25; 8:15277.
Zhou X, Sun L, Bracko O, Choi JW, Jia Y, Nana AL, Brady OA, Hernandez JCC, Nishimura N, Seeley WW, Hu F. PMID: 28541286; PMCID: PMC5477518.
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PubMed Mentions:
60 Fields:
Translation:
HumansAnimalsCells
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Precipitous Deterioration of Motor Function, Cognition, and Behavior. JAMA Neurol. 2017 05 01; 74(5):591-596.
Fernández-Fournier M, Perry DC, Tartaglia MC, de May M, Boxer A, Coppola G, Christine CW, Huang EJ, Seeley WW, Miller BL, DeArmond SJ, Grinberg LT, Geschwind MD. PMID: 28264087; PMCID: PMC5600817.
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PubMed Mentions: Fields:
Translation:
Humans
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Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis. Sci Transl Med. 2017 04 12; 9(385).
Ward ME, Chen R, Huang HY, Ludwig C, Telpoukhovskaia M, Taubes A, Boudin H, Minami SS, Reichert M, Albrecht P, Gelfand JM, Cruz-Herranz A, Cordano C, Alavi MV, Leslie S, Seeley WW, Miller BL, Bigio E, Mesulam MM, Bogyo MS, Mackenzie IR, Staropoli JF, Cotman SL, Huang EJ, Gan L, Green AJ. PMID: 28404863; PMCID: PMC5526610.
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PubMed Mentions:
103 Fields:
Translation:
HumansAnimalsCells
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Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging. Brain Imaging Behav. 2017 04; 11(2):391-400.
Yokoyama JS, Marx G, Brown JA, Bonham LW, Wang D, Coppola G, Seeley WW, Rosen HJ, Miller BL, Kramer JH, Dubal DB. PMID: 27714549; PMCID: PMC5382127.
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PubMed Mentions:
30 Fields:
Translation:
Humans
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Quantifying the accretion of hyperphosphorylated tau in the locus coeruleus and dorsal raphe nucleus: the pathological building blocks of early Alzheimer's disease. Neuropathol Appl Neurobiol. 2017 Aug; 43(5):393-408.
Ehrenberg AJ, Nguy AK, Theofilas P, Dunlop S, Suemoto CK, Di Lorenzo Alho AT, Leite RP, Diehl Rodriguez R, Mejia MB, Rüb U, Farfel JM, de Lucena Ferretti-Rebustini RE, Nascimento CF, Nitrini R, Pasquallucci CA, Jacob-Filho W, Miller B, Seeley WW, Heinsen H, Grinberg LT. PMID: 28117917; PMCID: PMC5642282.
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PubMed Mentions:
94 Fields:
Translation:
HumansCells
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Typical and atypical pathology in primary progressive aphasia variants. Ann Neurol. 2017 Mar; 81(3):430-443.
Spinelli EG, Mandelli ML, Miller ZA, Santos-Santos MA, Wilson SM, Agosta F, Grinberg LT, Huang EJ, Trojanowski JQ, Meyer M, Henry ML, Comi G, Rabinovici G, Rosen HJ, Filippi M, Miller BL, Seeley WW, Gorno-Tempini ML. PMID: 28133816; PMCID: PMC5421819.
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PubMed Mentions:
156 Fields:
Translation:
Humans
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Interhemispheric gene expression differences in the cerebral cortex of humans and macaque monkeys. Brain Struct Funct. 2017 Sep; 222(7):3241-3254.
Muntané G, Santpere G, Verendeev A, Seeley WW, Jacobs B, Hopkins WD, Navarro A, Sherwood CC. PMID: 28317062; PMCID: PMC5605391.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
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Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia. Acta Neuropathol. 2017 05; 133(5):825-837.
Yokoyama JS, Karch CM, Fan CC, Bonham LW, Kouri N, Ross OA, Rademakers R, Kim J, Wang Y, Höglinger GU, Müller U, Ferrari R, Hardy J, International FTD-Genomics Consortium (IFGC), Momeni P, Sugrue LP, Hess CP, James Barkovich A, Boxer AL, Seeley WW, Rabinovici GD, Rosen HJ, Miller BL, Schmansky NJ, Fischl B, Hyman BT, Dickson DW, Schellenberg GD, Andreassen OA, Dale AM, Desikan RS. PMID: 28271184; PMCID: PMC5429027.
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PubMed Mentions:
50 Fields:
Translation:
HumansCells
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Automating cell detection and classification in human brain fluorescent microscopy images using dictionary learning and sparse coding. J Neurosci Methods. 2017 Apr 15; 282:20-33.
Alegro M, Theofilas P, Nguy A, Castruita PA, Seeley W, Heinsen H, Ushizima DM, Grinberg LT. PMID: 28267565; PMCID: PMC5600818.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Frontotemporal dementia with the V337M MAPT mutation: Tau-PET and pathology correlations. Neurology. 2017 Feb 21; 88(8):758-766.
Spina S, Schonhaut DR, Boeve BF, Seeley WW, Ossenkoppele R, O'Neil JP, Lazaris A, Rosen HJ, Boxer AL, Perry DC, Miller BL, Dickson DW, Parisi JE, Jagust WJ, Murray ME, Rabinovici GD. PMID: 28130473; PMCID: PMC5344079.
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PubMed Mentions:
50 Fields:
Translation:
Humans
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Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106. Elife. 2017 01 10; 6.
Celona B, Dollen JV, Vatsavayai SC, Kashima R, Johnson JR, Tang AA, Hata A, Miller BL, Huang EJ, Krogan NJ, Seeley WW, Black BL. PMID: 28072389; PMCID: PMC5283830.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Focal temporal pole atrophy and network degeneration in semantic variant primary progressive aphasia. Brain. 2017 02; 140(2):457-471.
Collins JA, Montal V, Hochberg D, Quimby M, Mandelli ML, Makris N, Seeley WW, Gorno-Tempini ML, Dickerson BC. PMID: 28040670; PMCID: PMC5278308.
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PubMed Mentions:
58 Fields:
Translation:
Humans
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Network degeneration and dysfunction in presymptomatic C9ORF72 expansion carriers. Neuroimage Clin. 2017; 14:286-297.
Lee SE, Sias AC, Mandelli ML, Brown JA, Brown AB, Khazenzon AM, Vidovszky AA, Zanto TP, Karydas AM, Pribadi M, Dokuru D, Coppola G, Geschwind DH, Rademakers R, Gorno-Tempini ML, Rosen HJ, Miller BL, Seeley WW. PMID: 28337409; PMCID: PMC5349617.
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PubMed Mentions:
72 Fields:
Translation:
HumansCells
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Tau prions from Alzheimer's disease and chronic traumatic encephalopathy patients propagate in cultured cells. Proc Natl Acad Sci U S A. 2016 12 13; 113(50):E8187-E8196.
Woerman AL, Aoyagi A, Patel S, Kazmi SA, Lobach I, Grinberg LT, McKee AC, Seeley WW, Olson SH, Prusiner SB. PMID: 27911827; PMCID: PMC5167200.
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PubMed Mentions:
91 Fields:
Translation:
HumansCells
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Regional correlations between [11C]PIB PET and post-mortem burden of amyloid-beta pathology in a diverse neuropathological cohort. Neuroimage Clin. 2017; 13:130-137.
Seo SW, Ayakta N, Grinberg LT, Villeneuve S, Lehmann M, Reed B, DeCarli C, Miller BL, Rosen HJ, Boxer AL, O'Neil JP, Jin LW, Seeley WW, Jagust WJ, Rabinovici GD. PMID: 27981028; PMCID: PMC5144753.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture. Neurol Neuroimmunol Neuroinflamm. 2016 Dec; 3(6):e301.
Miller ZA, Sturm VE, Camsari GB, Karydas A, Yokoyama JS, Grinberg LT, Boxer AL, Rosen HJ, Rankin KP, Gorno-Tempini ML, Coppola G, Geschwind DH, Rademakers R, Seeley WW, Graff-Radford NR, Miller BL. PMID: 27844039; PMCID: PMC5087253.
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PubMed Mentions:
46 Fields:
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Timing and significance of pathological features in C9orf72 expansion-associated frontotemporal dementia. Brain. 2016 12; 139(Pt 12):3202-3216.
Vatsavayai SC, Yoon SJ, Gardner RC, Gendron TF, Vargas JN, Trujillo A, Pribadi M, Phillips JJ, Gaus SE, Hixson JD, Garcia PA, Rabinovici GD, Coppola G, Geschwind DH, Petrucelli L, Miller BL, Seeley WW. PMID: 27797809; PMCID: PMC5790143.
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PubMed Mentions:
89 Fields:
Translation:
HumansCells
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An autopsy confirmed case of progressive supranuclear palsy with predominant cerebellar ataxia. J Neurol. 2016 Dec; 263(12):2540-2543.
Lee MJ, Lee JH, Kim BK, Lee JH, Lee YM, Kim SJ, Shin JH, Shin MJ, Ahn JW, Sung S, Choi KU, Jung DS, Jung NY, Seeley WW, Huh GY, Kim EJ. PMID: 27761640.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Cognition and neuropsychiatry in behavioral variant frontotemporal dementia by disease stage. Neurology. 2016 10 04; 87(14):1523.
Bertoux M, Sarazin M, Pasquier F, Bottlaender M, de Souza LC, Mioshi E, Hornberger M, Ranasinghe KG, Rankin KP, Lobach IV, Kramer JH, Sturm VE, Bettcher BM, Possin K, You SC, Lamarre AK, Shany-Ur T, Stephens ML, Perry DC, Lee SE, Miller ZA, Gorno-Tempini ML, Rosen HJ, Boxer A, Seeley WW, Rabinovici GD, Vossel KA, Miller BL. PMID: 27698154; PMCID: PMC5990306.
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PubMed Mentions: Fields:
Translation:
Humans
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Distinct Subtypes of Behavioral Variant Frontotemporal Dementia Based on Patterns of Network Degeneration. JAMA Neurol. 2016 Sep 01; 73(9):1078-88.
Ranasinghe KG, Rankin KP, Pressman PS, Perry DC, Lobach IV, Seeley WW, Coppola G, Karydas AM, Grinberg LT, Shany-Ur T, Lee SE, Rabinovici GD, Rosen HJ, Gorno-Tempini ML, Boxer AL, Miller ZA, Chiong W, DeMay M, Kramer JH, Possin KL, Sturm VE, Bettcher BM, Neylan M, Zackey DD, Nguyen LA, Ketelle R, Block N, Wu TQ, Dallich A, Russek N, Caplan A, Geschwind DH, Vossel KA, Miller BL. PMID: 27429218; PMCID: PMC5024785.
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PubMed Mentions:
70 Fields:
Translation:
Humans
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Locus coeruleus volume and cell population changes during Alzheimer's disease progression: A stereological study in human postmortem brains with potential implication for early-stage biomarker discovery. Alzheimers Dement. 2017 Mar; 13(3):236-246.
Theofilas P, Ehrenberg AJ, Dunlop S, Di Lorenzo Alho AT, Nguy A, Leite REP, Rodriguez RD, Mejia MB, Suemoto CK, Ferretti-Rebustini REL, Polichiso L, Nascimento CF, Seeley WW, Nitrini R, Pasqualucci CA, Jacob Filho W, Rueb U, Neuhaus J, Heinsen H, Grinberg LT. PMID: 27513978; PMCID: PMC5298942.
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PubMed Mentions:
154 Fields:
Translation:
HumansCells
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Healthy brain connectivity predicts atrophy progression in non-fluent variant of primary progressive aphasia. Brain. 2016 10; 139(Pt 10):2778-2791.
Mandelli ML, Vilaplana E, Brown JA, Hubbard HI, Binney RJ, Attygalle S, Santos-Santos MA, Miller ZA, Pakvasa M, Henry ML, Rosen HJ, Henry RG, Rabinovici GD, Miller BL, Seeley WW, Gorno-Tempini ML. PMID: 27497488; PMCID: PMC5035819.
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PubMed Mentions:
67 Fields:
Translation:
Humans
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Atrophy, hypometabolism and clinical trajectories in patients with amyloid-negative Alzheimer's disease. Brain. 2016 09; 139(Pt 9):2528-39.
Chételat G, Ossenkoppele R, Villemagne VL, Perrotin A, Landeau B, Mézenge F, Jagust WJ, Dore V, Miller BL, Egret S, Seeley WW, van der Flier WM, La Joie R, Ames D, van Berckel BN, Scheltens P, Barkhof F, Rowe CC, Masters CL, de La Sayette V, Bouwman F, Rabinovici GD. PMID: 27357349; PMCID: PMC6276935.
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PubMed Mentions:
30 Fields:
Translation:
Humans
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Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment. Mol Neurodegener. 2016 06 29; 11(1):47.
Sohn PD, Tracy TE, Son HI, Zhou Y, Leite RE, Miller BL, Seeley WW, Grinberg LT, Gan L. PMID: 27356871; PMCID: PMC4928318.
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PubMed Mentions:
69 Fields:
Translation:
HumansAnimalsCells
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Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis. Neuron. 2016 07 06; 91(1):41-55.
Lee S, Shang Y, Redmond SA, Urisman A, Tang AA, Li KH, Burlingame AL, Pak RA, Jovicic A, Gitler AD, Wang J, Gray NS, Seeley WW, Siddique T, Bigio EH, Lee VM, Trojanowski JQ, Chan JR, Huang EJ. PMID: 27321923; PMCID: PMC4938715.
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PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
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Features of Patients With Nonfluent/Agrammatic Primary Progressive Aphasia With Underlying Progressive Supranuclear Palsy Pathology or Corticobasal Degeneration. JAMA Neurol. 2016 06 01; 73(6):733-42.
Santos-Santos MA, Mandelli ML, Binney RJ, Ogar J, Wilson SM, Henry ML, Hubbard HI, Meese M, Attygalle S, Rosenberg L, Pakvasa M, Trojanowski JQ, Grinberg LT, Rosen H, Boxer AL, Miller BL, Seeley WW, Gorno-Tempini ML. PMID: 27111692; PMCID: PMC4924620.
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PubMed Mentions:
65 Fields:
Translation:
Humans
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Schizophrenia as a mimic of behavioral variant frontotemporal dementia. Neurocase. 2016 06; 22(3):285-8.
Kerssens CJ, Krudop WA, Prins ND, van Berckel BN, Rozemuller A, Seeley WW, Scheltens P, Stek ML, Pijnenburg YA. PMID: 27223596; PMCID: PMC5790990.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Brain Modulyzer: Interactive Visual Analysis of Functional Brain Connectivity. IEEE/ACM Trans Comput Biol Bioinform. 2016 May 9.
Murugesan S, Bouchard K, Brown JA, Hamann B, Seeley WW, Trujillo A, Weber GH. PMID: 27244747.
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PubMed Mentions:
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Brain Modulyzer: Interactive Visual Analysis of Functional Brain Connectivity. IEEE/ACM Trans Comput Biol Bioinform. 2017 Jul-Aug; 14(4):805-818.
Murugesan S, Bouchard K, Brown JA, Hamann B, Seeley WW, Trujillo A, Weber GH. PMID: 28113724; PMCID: PMC5585064.
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PubMed Mentions:
2 Fields:
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Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation. Cell. 2016 May 05; 165(4):921-35.
Lui H, Zhang J, Makinson SR, Cahill MK, Kelley KW, Huang HY, Shang Y, Oldham MC, Martens LH, Gao F, Coppola G, Sloan SA, Hsieh CL, Kim CC, Bigio EH, Weintraub S, Mesulam MM, Rademakers R, Mackenzie IR, Seeley WW, Karydas A, Miller BL, Borroni B, Ghidoni R, Farese RV, Paz JT, Barres BA, Huang EJ. PMID: 27114033; PMCID: PMC4860138.
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PubMed Mentions:
352 Fields:
Translation:
HumansAnimalsCells
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Dominant hemisphere lateralization of cortical parasympathetic control as revealed by frontotemporal dementia. Proc Natl Acad Sci U S A. 2016 Apr 26; 113(17):E2430-9.
Guo CC, Sturm VE, Zhou J, Gennatas ED, Trujillo AJ, Hua AY, Crawford R, Stables L, Kramer JH, Rankin K, Levenson RW, Rosen HJ, Miller BL, Seeley WW. PMID: 27071080; PMCID: PMC4855566.
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PubMed Mentions:
50 Fields:
Translation:
Humans
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Distinct Lysosomal Network Protein Profiles in Parkinsonian Syndrome Cerebrospinal Fluid. J Parkinsons Dis. 2016 04 02; 6(2):307-15.
Boman A, Svensson S, Boxer A, Rojas JC, Seeley WW, Karydas A, Miller B, Kågedal K, Svenningsson P. PMID: 27061067; PMCID: PMC4927933.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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FLEXITau: Quantifying Post-translational Modifications of Tau Protein in Vitro and in Human Disease. Anal Chem. 2016 Apr 05; 88(7):3704-14.
Mair W, Muntel J, Tepper K, Tang S, Biernat J, Seeley WW, Kosik KS, Mandelkow E, Steen H, Steen JA. PMID: 26877193; PMCID: PMC5808556.
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PubMed Mentions:
69 Fields:
Translation:
HumansAnimalsCells
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Structural connectivity of the human anterior temporal lobe: A diffusion magnetic resonance imaging study. Hum Brain Mapp. 2016 06; 37(6):2210-22.
Papinutto N, Galantucci S, Mandelli ML, Gesierich B, Jovicich J, Caverzasi E, Henry RG, Seeley WW, Miller BL, Shapiro KA, Gorno-Tempini ML. PMID: 26945805; PMCID: PMC4922800.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Cognition and neuropsychiatry in behavioral variant frontotemporal dementia by disease stage. Neurology. 2016 Feb 16; 86(7):600-10.
Ranasinghe KG, Rankin KP, Lobach IV, Kramer JH, Sturm VE, Bettcher BM, Possin K, Christine You S, Lamarre AK, Shany-Ur T, Stephens ML, Perry DC, Lee SE, Miller ZA, Gorno-Tempini ML, Rosen HJ, Boxer A, Seeley WW, Rabinovici GD, Vossel KA, Miller BL. PMID: 26802093; PMCID: PMC4762418.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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Selective Frontoinsular von Economo Neuron and Fork Cell Loss in Early Behavioral Variant Frontotemporal Dementia. Cereb Cortex. 2016 Apr; 26(4):1843.
Kim EJ, Sidhu M, Gaus SE, Huang EJ, Hof PR, Miller BL, DeArmond SJ, Seeley WW. PMID: 26796215; PMCID: PMC6272814.
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PubMed Mentions:
4 Fields:
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Deep clinical and neuropathological phenotyping of Pick disease. Ann Neurol. 2016 Feb; 79(2):272-87.
Irwin DJ, Brettschneider J, McMillan CT, Cooper F, Olm C, Arnold SE, Van Deerlin VM, Seeley WW, Miller BL, Lee EB, Lee VM, Grossman M, Trojanowski JQ. PMID: 26583316; PMCID: PMC4755803.
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PubMed Mentions:
101 Fields:
Translation:
Humans
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Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy. Acta Neuropathol. 2016 Jan; 131(1):87-102.
Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H, Cairns NJ, Crary JF, Duyckaerts C, Ghetti B, Halliday GM, Ironside JW, Love S, Mackenzie IR, Munoz DG, Murray ME, Nelson PT, Takahashi H, Trojanowski JQ, Ansorge O, Arzberger T, Baborie A, Beach TG, Bieniek KF, Bigio EH, Bodi I, Dugger BN, Feany M, Gelpi E, Gentleman SM, Giaccone G, Hatanpaa KJ, Heale R, Hof PR, Hofer M, Hortobágyi T, Jellinger K, Jicha GA, Ince P, Kofler J, Kövari E, Kril JJ, Mann DM, Matej R, McKee AC, McLean C, Milenkovic I, Montine TJ, Murayama S, Lee EB, Rahimi J, Rodriguez RD, Rozemüller A, Schneider JA, Schultz C, Seeley W, Seilhean D, Smith C, Tagliavini F, Takao M, Thal DR, Toledo JB, Tolnay M, Troncoso JC, Vinters HV, Weis S, Wharton SB, White CL, Wisniewski T, Woulfe JM, Yamada M, Dickson DW. PMID: 26659578; PMCID: PMC4879001.
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PubMed Mentions:
228 Fields:
Translation:
HumansAnimalsCells
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Primary chronic traumatic encephalopathy in an older patient with late-onset AD phenotype. Neurol Clin Pract. 2015 Dec; 5(6):475-479.
Fredericks CA, Koestler M, Seeley W, Miller B, Boxer A, Grinberg LT. PMID: 26716062; PMCID: PMC4684670.
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PubMed Mentions:
2
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Two insular regions are differentially involved in behavioral variant FTD and nonfluent/agrammatic variant PPA. Cortex. 2016 Jan; 74:149-57.
Mandelli ML, Vitali P, Santos M, Henry M, Gola K, Rosenberg L, Dronkers N, Miller B, Seeley WW, Gorno-Tempini ML. PMID: 26673947; PMCID: PMC4755480.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Propagation of prions causing synucleinopathies in cultured cells. Proc Natl Acad Sci U S A. 2015 Sep 01; 112(35):E4949-58.
Woerman AL, Stöhr J, Aoyagi A, Rampersaud R, Krejciova Z, Watts JC, Ohyama T, Patel S, Widjaja K, Oehler A, Sanders DW, Diamond MI, Seeley WW, Middleton LT, Gentleman SM, Mordes DA, Südhof TC, Giles K, Prusiner SB. PMID: 26286986; PMCID: PMC4568231.
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PubMed Mentions:
125 Fields:
Translation:
HumansAnimalsCells
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Atrophy patterns in early clinical stages across distinct phenotypes of Alzheimer's disease. Hum Brain Mapp. 2015 Nov; 36(11):4421-37.
Ossenkoppele R, Cohn-Sheehy BI, La Joie R, Vogel JW, Möller C, Lehmann M, van Berckel BN, Seeley WW, Pijnenburg YA, Gorno-Tempini ML, Kramer JH, Barkhof F, Rosen HJ, van der Flier WM, Jagust WJ, Miller BL, Scheltens P, Rabinovici GD. PMID: 26260856; PMCID: PMC4692964.
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PubMed Mentions:
128 Fields:
Translation:
HumansAnimals
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Loss of functional connectivity is greater outside the default mode network in nonfamilial early-onset Alzheimer's disease variants. Neurobiol Aging. 2015 Oct; 36(10):2678-86.
Lehmann M, Madison C, Ghosh PM, Miller ZA, Greicius MD, Kramer JH, Coppola G, Miller BL, Jagust WJ, Gorno-Tempini ML, Seeley WW, Rabinovici GD. PMID: 26242705; PMCID: PMC4698410.
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PubMed Mentions:
41 Fields:
Translation:
Humans
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The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features. Brain. 2015 Sep; 138(Pt 9):2732-49.
Ossenkoppele R, Pijnenburg YA, Perry DC, Cohn-Sheehy BI, Scheltens NM, Vogel JW, Kramer JH, van der Vlies AE, La Joie R, Rosen HJ, van der Flier WM, Grinberg LT, Rozemuller AJ, Huang EJ, van Berckel BN, Miller BL, Barkhof F, Jagust WJ, Scheltens P, Seeley WW, Rabinovici GD. PMID: 26141491; PMCID: PMC4623840.
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PubMed Mentions:
179 Fields:
Translation:
Humans
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Detection of TDP-43 oligomers in frontotemporal lobar degeneration-TDP. Ann Neurol. 2015 Aug; 78(2):211-21.
Kao PF, Chen YR, Liu XB, DeCarli C, Seeley WW, Jin LW. PMID: 25921485; PMCID: PMC4822421.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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The Progranulin Cleavage Products, Granulins, Exacerbate TDP-43 Toxicity and Increase TDP-43 Levels. J Neurosci. 2015 Jun 24; 35(25):9315-28.
Salazar DA, Butler VJ, Argouarch AR, Hsu TY, Mason A, Nakamura A, McCurdy H, Cox D, Ng R, Pan G, Seeley WW, Miller BL, Kao AW. PMID: 26109656; PMCID: PMC4478251.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimals
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Amyloid in dementia associated with familial FTLD: not an innocent bystander. Neurocase. 2016; 22(1):76-83.
Naasan G, Rabinovici GD, Ghosh P, Elofson JD, Miller BL, Coppola G, Karydas A, Fong J, Perry D, Lee SE, Yokoyama JS, Seeley WW, Kramer JH, Weiner MW, Schuff N, Jagust WJ, Grinberg LT, Pribadi M, Yang Z, Sears R, Klein E, Wojta K, Rosen HJ. PMID: 26040468; PMCID: PMC4662906.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation. Brain. 2015 Jul; 138(Pt 7):2020-33.
Villeneuve S, Rabinovici GD, Cohn-Sheehy BI, Madison C, Ayakta N, Ghosh PM, La Joie R, Arthur-Bentil SK, Vogel JW, Marks SM, Lehmann M, Rosen HJ, Reed B, Olichney J, Boxer AL, Miller BL, Borys E, Jin LW, Huang EJ, Grinberg LT, DeCarli C, Seeley WW, Jagust W. PMID: 25953778; PMCID: PMC4806716.
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PubMed Mentions:
208 Fields:
Translation:
Humans
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A novel mutation P112H in the TARDBP gene associated with frontotemporal lobar degeneration without motor neuron disease and abundant neuritic amyloid plaques. Acta Neuropathol Commun. 2015 Apr 03; 3:19.
Moreno F, Rabinovici GD, Karydas A, Miller Z, Hsu SC, Legati A, Fong J, Schonhaut D, Esselmann H, Watson C, Stephens ML, Kramer J, Wiltfang J, Seeley WW, Miller BL, Coppola G, Grinberg LT. PMID: 25853458; PMCID: PMC4382926.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Familial behavioral variant frontotemporal dementia associated with astrocyte-predominant tauopathy. J Neuropathol Exp Neurol. 2015 Apr; 74(4):370-9.
Ferrer I, Legati A, García-Monco JC, Gomez-Beldarrain M, Carmona M, Blanco R, Seeley WW, Coppola G. PMID: 25756587; PMCID: PMC4366320.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Memory profiles in pathology or biomarker confirmed Alzheimer disease and frontotemporal dementia. Alzheimer Dis Assoc Disord. 2015 Apr-Jun; 29(2):135-40.
Mansoor Y, Jastrzab L, Dutt S, Miller BL, Seeley WW, Kramer JH. PMID: 25203512; PMCID: PMC4362796.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Predicting amyloid status in corticobasal syndrome using modified clinical criteria, magnetic resonance imaging and fluorodeoxyglucose positron emission tomography. Alzheimers Res Ther. 2015; 7(1):8.
Sha SJ, Ghosh PM, Lee SE, Corbetta-Rastelli C, Jagust WJ, Kornak J, Rankin KP, Grinberg LT, Vinters HV, Mendez MF, Dickson DW, Seeley WW, Gorno-Tempini M, Kramer J, Miller BL, Boxer AL, Rabinovici GD. PMID: 25733984; PMCID: PMC4346122.
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PubMed Mentions:
13 Fields:
-
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PubMed Mentions:
41 Fields:
Translation:
Humans
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Defects of mutant DNMT1 are linked to a spectrum of neurological disorders. Brain. 2015 Apr; 138(Pt 4):845-61.
Baets J, Duan X, Wu Y, Smith G, Seeley WW, Mademan I, McGrath NM, Beadell NC, Khoury J, Botuyan MV, Mer G, Worrell GA, Hojo K, DeLeon J, Laura M, Liu YT, Senderek J, Weis J, Van den Bergh P, Merrill SL, Reilly MM, Houlden H, Grossman M, Scherer SS, De Jonghe P, Dyck PJ, Klein CJ. PMID: 25678562; PMCID: PMC5014076.
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PubMed Mentions:
42 Fields:
Translation:
HumansCells
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Impaired Recognition and Regulation of Disgust Is Associated with Distinct but Partially Overlapping Patterns of Decreased Gray Matter Volume in the Ventroanterior Insula. Biol Psychiatry. 2015 Oct 01; 78(7):505-14.
Woolley JD, Strobl EV, Sturm VE, Shany-Ur T, Poorzand P, Grossman S, Nguyen L, Eckart JA, Levenson RW, Seeley WW, Miller BL, Rankin KP. PMID: 25890642; PMCID: PMC4529378.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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The anterior insula shows heightened interictal intrinsic connectivity in migraine without aura. Neurology. 2015 Mar 10; 84(10):1043-50.
Tso AR, Trujillo A, Guo CC, Goadsby PJ, Seeley WW. PMID: 25663219; PMCID: PMC4352101.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Rarity of the Alzheimer disease-protective APP A673T variant in the United States. JAMA Neurol. 2015 Feb; 72(2):209-16.
Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E, Alzheimer's Disease Genetics Consortium, Lin CF, Dombroski BA, Cantwell LB, Partch A, Valladares O, Hakonarson H, St George-Hyslop P, Green RC, Goate AM, Foroud TM, Carney RM, Larson EB, Behrens TW, Kauwe JS, Haines JL, Farrer LA, Pericak-Vance MA, Mayeux R, Schellenberg GD, National Institute on Aging-Late-Onset Alzheimer’s Disease (NIA-LOAD) Family Study, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barmada M, Barnes LL, Beach TG, Becker JT, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carroll SL, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Demirci FY, Dick M, Dickson DW, Duara R, Ertekin-Taner N, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Graff-Radford NR, Growdon JH, Hamilton RL, Hamilton-Nelson KL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Jun G, Kamboh MI, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lopez OL, Lunetta KL, Lyketsos CG, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam WM, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Murrell JR, Olichney JM, Parisi JE, Perry W, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L. PMID: 25531812; PMCID: PMC4324097.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia. Nat Med. 2014 Dec; 20(12):1444-51.
Gascon E, Lynch K, Ruan H, Almeida S, Verheyden JM, Seeley WW, Dickson DW, Petrucelli L, Sun D, Jiao J, Zhou H, Jakovcevski M, Akbarian S, Yao WD, Gao FB. PMID: 25401692; PMCID: PMC4257887.
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PubMed Mentions:
92 Fields:
Translation:
AnimalsCells
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Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov; 71(11):1394-404.
Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA, Alzheimer Disease Genetics Consortium, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barnes LL, Beach TG, Becker JT, Beekly D, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carrasquillo MM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Dick M, Dickson DW, Duara R, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lin CF, Lopez OL, Lyketsos CG, Mack WJ, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Murrell JR, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Valladares O, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L. PMID: 25199842; PMCID: PMC4314944.
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PubMed Mentions:
98 Fields:
Translation:
Humans
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Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathol. 2014 Dec; 128(6):755-66.
Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, Hyman BT, Jellinger K, Jicha GA, Kovacs GG, Knopman DS, Kofler J, Kukull WA, Mackenzie IR, Masliah E, McKee A, Montine TJ, Murray ME, Neltner JH, Santa-Maria I, Seeley WW, Serrano-Pozo A, Shelanski ML, Stein T, Takao M, Thal DR, Toledo JB, Troncoso JC, Vonsattel JP, White CL, Wisniewski T, Woltjer RL, Yamada M, Nelson PT. PMID: 25348064; PMCID: PMC4257842.
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PubMed Mentions:
676 Fields:
Translation:
Humans
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Clinicopathological Study of Patients With C9ORF72-Associated Frontotemporal Dementia Presenting With Delusions. J Geriatr Psychiatry Neurol. 2015 Jun; 28(2):99-107.
Shinagawa S, Naasan G, Karydas AM, Coppola G, Pribadi M, Seeley WW, Trojanowski JQ, Miller BL, Grinberg LT. PMID: 25342578; PMCID: PMC4408221.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Damage to left frontal regulatory circuits produces greater positive emotional reactivity in frontotemporal dementia. Cortex. 2015 Mar; 64:55-67.
Sturm VE, Yokoyama JS, Eckart JA, Zakrzewski J, Rosen HJ, Miller BL, Seeley WW, Levenson RW. PMID: 25461707; PMCID: PMC4346386.
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PubMed Mentions:
30 Fields:
Translation:
Humans
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Altered network connectivity in frontotemporal dementia with C9orf72 hexanucleotide repeat expansion. Brain. 2014 Nov; 137(Pt 11):3047-60.
Lee SE, Khazenzon AM, Trujillo AJ, Guo CC, Yokoyama JS, Sha SJ, Takada LT, Karydas AM, Block NR, Coppola G, Pribadi M, Geschwind DH, Rademakers R, Fong JC, Weiner MW, Boxer AL, Kramer JH, Rosen HJ, Miller BL, Seeley WW. PMID: 25273996; PMCID: PMC4208465.
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PubMed Mentions:
88 Fields:
Translation:
HumansCells
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Genetic modifiers in carriers of repeat expansions in the C9ORF72 gene. Mol Neurodegener. 2014 Sep 20; 9:38.
van Blitterswijk M, Mullen B, Wojtas A, Heckman MG, Diehl NN, Baker MC, DeJesus-Hernandez M, Brown PH, Murray ME, Hsiung GY, Stewart H, Karydas AM, Finger E, Kertesz A, Bigio EH, Weintraub S, Mesulam M, Hatanpaa KJ, White CL, Neumann M, Strong MJ, Beach TG, Wszolek ZK, Lippa C, Caselli R, Petrucelli L, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Mackenzie IR, Seeley WW, Grinberg LT, Miller BL, Boylan KB, Graff-Radford NR, Boeve BF, Dickson DW, Rademakers R. PMID: 25239657; PMCID: PMC4190282.
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PubMed Mentions:
36 Fields:
Translation:
HumansCells
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Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD. J Exp Med. 2014 Sep 22; 211(10):1937-45.
Ward ME, Taubes A, Chen R, Miller BL, Sephton CF, Gelfand JM, Minami S, Boscardin J, Martens LH, Seeley WW, Yu G, Herz J, Filiano AJ, Arrant AE, Roberson ED, Kraft TW, Farese RV, Green A, Gan L. PMID: 25155018; PMCID: PMC4172214.
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PubMed Mentions:
58 Fields:
Translation:
HumansAnimals
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Recommendations of the Alzheimer's disease-related dementias conference. Neurology. 2014 Aug 26; 83(9):851-60.
Montine TJ, Koroshetz WJ, Babcock D, Dickson DW, Galpern WR, Glymour MM, Greenberg SM, Hutton ML, Knopman DS, Kuzmichev AN, Manly JJ, Marder KS, Miller BL, Phelps CH, Seeley WW, Sieber BA, Silverberg NB, Sutherland M, Torborg CL, Waddy SP, Zlokovic BV, Corriveau RA, ADRD 2013 Conference Organizing Committee. PMID: 25080517; PMCID: PMC4155046.
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PubMed Mentions:
66 Fields:
Translation:
Humans
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Structural and functional brain connectivity in presymptomatic familial frontotemporal dementia. Neurology. 2014 Jul 08; 83(2):e19-26.
Dopper EG, Rombouts SA, Jiskoot LC, den Heijer T, de Graaf JR, de Koning I, Hammerschlag AR, Seelaar H, Seeley WW, Veer IM, van Buchem MA, Rizzu P, van Swieten JC. PMID: 25002573.
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PubMed Mentions:
78 Fields:
Translation:
Humans
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Frontotemporal dementia and its subtypes: a genome-wide association study. Lancet Neurol. 2014 Jul; 13(7):686-99.
Ferrari R, Hernandez DG, Nalls MA, Rohrer JD, Ramasamy A, Kwok JB, Dobson-Stone C, Brooks WS, Schofield PR, Halliday GM, Hodges JR, Piguet O, Bartley L, Thompson E, Haan E, Hernández I, Ruiz A, Boada M, Borroni B, Padovani A, Cruchaga C, Cairns NJ, Benussi L, Binetti G, Ghidoni R, Forloni G, Galimberti D, Fenoglio C, Serpente M, Scarpini E, Clarimón J, Lleó A, Blesa R, Waldö ML, Nilsson K, Nilsson C, Mackenzie IR, Hsiung GY, Mann DM, Grafman J, Morris CM, Attems J, Griffiths TD, McKeith IG, Thomas AJ, Pietrini P, Huey ED, Wassermann EM, Baborie A, Jaros E, Tierney MC, Pastor P, Razquin C, Ortega-Cubero S, Alonso E, Perneczky R, Diehl-Schmid J, Alexopoulos P, Kurz A, Rainero I, Rubino E, Pinessi L, Rogaeva E, St George-Hyslop P, Rossi G, Tagliavini F, Giaccone G, Rowe JB, Schlachetzki JC, Uphill J, Collinge J, Mead S, Danek A, Van Deerlin VM, Grossman M, Trojanowski JQ, van der Zee J, Deschamps W, Van Langenhove T, Cruts M, Van Broeckhoven C, Cappa SF, Le Ber I, Hannequin D, Golfier V, Vercelletto M, Brice A, Nacmias B, Sorbi S, Bagnoli S, Piaceri I, Nielsen JE, Hjermind LE, Riemenschneider M, Mayhaus M, Ibach B, Gasparoni G, Pichler S, Gu W, Rossor MN, Fox NC, Warren JD, Spillantini MG, Morris HR, Rizzu P, Heutink P, Snowden JS, Rollinson S, Richardson A, Gerhard A, Bruni AC, Maletta R, Frangipane F, Cupidi C, Bernardi L, Anfossi M, Gallo M, Conidi ME, Smirne N, Rademakers R, Baker M, Dickson DW, Graff-Radford NR, Petersen RC, Knopman D, Josephs KA, Boeve BF, Parisi JE, Seeley WW, Miller BL, Karydas AM, Rosen H, van Swieten JC, Dopper EG, Seelaar H, Pijnenburg YA, Scheltens P, Logroscino G, Capozzo R, Novelli V, Puca AA, Franceschi M, Postiglione A, Milan G, Sorrentino P, Kristiansen M, Chiang HH, Graff C, Pasquier F, Rollin A, Deramecourt V, Lebert F, Kapogiannis D, Ferrucci L, Pickering-Brown S, Singleton AB, Hardy J, Momeni P. PMID: 24943344; PMCID: PMC4112126.
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PubMed Mentions:
154 Fields:
Translation:
Humans
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Distinct tau prion strains propagate in cells and mice and define different tauopathies. Neuron. 2014 Jun 18; 82(6):1271-88.
Sanders DW, Kaufman SK, DeVos SL, Sharma AM, Mirbaha H, Li A, Barker SJ, Foley AC, Thorpe JR, Serpell LC, Miller TM, Grinberg LT, Seeley WW, Diamond MI. PMID: 24857020; PMCID: PMC4171396.
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PubMed Mentions:
480 Fields:
Translation:
HumansAnimalsCells
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Ataxin-2 as potential disease modifier in C9ORF72 expansion carriers. Neurobiol Aging. 2014 Oct; 35(10):2421.e13-7.
van Blitterswijk M, Mullen B, Heckman MG, Baker MC, DeJesus-Hernandez M, Brown PH, Murray ME, Hsiung GY, Stewart H, Karydas AM, Finger E, Kertesz A, Bigio EH, Weintraub S, Mesulam M, Hatanpaa KJ, White CL, Neumann M, Strong MJ, Beach TG, Wszolek ZK, Lippa C, Caselli R, Petrucelli L, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Mackenzie IR, Seeley WW, Grinberg LT, Miller BL, Boylan KB, Graff-Radford NR, Boeve BF, Dickson DW, Rademakers R. PMID: 24866401; PMCID: PMC4105839.
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PubMed Mentions:
47 Fields:
Translation:
HumansCells
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View in:
PubMed Mentions:
44 Fields:
Translation:
Humans
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The functional oculomotor network and saccadic cognitive control in healthy elders. Neuroimage. 2014 Jul 15; 95:61-8.
Pa J, Dutt S, Mirsky JB, Heuer HW, Keselman P, Kong E, Trujillo A, Gazzaley A, Kramer JH, Seeley WW, Miller BL, Boxer AL. PMID: 24675647; PMCID: PMC4043928.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Network dysfunction in Alzheimer's disease and frontotemporal dementia: implications for psychiatry. Biol Psychiatry. 2014 Apr 01; 75(7):565-73.
Zhou J, Seeley WW. PMID: 24629669.
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PubMed Mentions:
96 Fields:
Translation:
Humans
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TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia. Acta Neuropathol. 2014 Mar; 127(3):397-406.
van Blitterswijk M, Mullen B, Nicholson AM, Bieniek KF, Heckman MG, Baker MC, DeJesus-Hernandez M, Finch NA, Brown PH, Murray ME, Hsiung GY, Stewart H, Karydas AM, Finger E, Kertesz A, Bigio EH, Weintraub S, Mesulam M, Hatanpaa KJ, White CL, Strong MJ, Beach TG, Wszolek ZK, Lippa C, Caselli R, Petrucelli L, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Mackenzie IR, Seeley WW, Grinberg LT, Miller BL, Boylan KB, Graff-Radford NR, Boeve BF, Dickson DW, Rademakers R. PMID: 24385136; PMCID: PMC3944829.
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PubMed Mentions:
78 Fields:
Translation:
HumansCells
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Cerebrospinal fluid neurofilament concentration reflects disease severity in frontotemporal degeneration. Ann Neurol. 2014 Jan; 75(1):116-26.
Scherling CS, Hall T, Berisha F, Klepac K, Karydas A, Coppola G, Kramer JH, Rabinovici G, Ahlijanian M, Miller BL, Seeley W, Grinberg LT, Rosen H, Meredith J, Boxer AL. PMID: 24242746; PMCID: PMC4020786.
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PubMed Mentions:
124 Fields:
Translation:
Humans
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Practical utility of amyloid and FDG-PET in an academic dementia center. Neurology. 2014 Jan 21; 82(3):230-8.
Sánchez-Juan P, Ghosh PM, Hagen J, Gesierich B, Henry M, Grinberg LT, O'Neil JP, Janabi M, Huang EJ, Trojanowski JQ, Vinters HV, Gorno-Tempini M, Seeley WW, Boxer AL, Rosen HJ, Kramer JH, Miller BL, Jagust WJ, Rabinovici GD. PMID: 24353340; PMCID: PMC3902757.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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In vivo signatures of nonfluent/agrammatic primary progressive aphasia caused by FTLD pathology. Neurology. 2014 Jan 21; 82(3):239-47.
Caso F, Mandelli ML, Henry M, Gesierich B, Bettcher BM, Ogar J, Filippi M, Comi G, Magnani G, Sidhu M, Trojanowski JQ, Huang EJ, Grinberg LT, Miller BL, Dronkers N, Seeley WW, Gorno-Tempini ML. PMID: 24353332; PMCID: PMC3902758.
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PubMed Mentions:
29 Fields:
Translation:
Humans
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Neurodegenerative disease phenotypes in carriers of MAPT p.A152T, a risk factor for frontotemporal dementia spectrum disorders and Alzheimer disease. Alzheimer Dis Assoc Disord. 2013 Oct-Dec; 27(4):302-9.
Lee SE, Tartaglia MC, Yener G, Genç S, Seeley WW, Sanchez-Juan P, Moreno F, Mendez MF, Klein E, Rademakers R, López de Munain A, Combarros O, Kramer JH, Kenet RO, Boxer AL, Geschwind MD, Gorno-Tempini ML, Karydas AM, Rabinovici GD, Coppola G, Geschwind DH, Miller BL. PMID: 23518664; PMCID: PMC3796183.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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Anterior temporal lobe degeneration produces widespread network-driven dysfunction. Brain. 2013 Oct; 136(Pt 10):2979-91.
Guo CC, Gorno-Tempini ML, Gesierich B, Henry M, Trujillo A, Shany-Ur T, Jovicich J, Robinson SD, Kramer JH, Rankin KP, Miller BL, Seeley WW. PMID: 24072486; PMCID: PMC3857932.
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PubMed Mentions:
94 Fields:
Translation:
Humans
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Seizures and epileptiform activity in the early stages of Alzheimer disease. JAMA Neurol. 2013 Sep 01; 70(9):1158-66.
Vossel KA, Beagle AJ, Rabinovici GD, Shu H, Lee SE, Naasan G, Hegde M, Cornes SB, Henry ML, Nelson AB, Seeley WW, Geschwind MD, Gorno-Tempini ML, Shih T, Kirsch HE, Garcia PA, Miller BL, Mucke L. PMID: 23835471; PMCID: PMC4013391.
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PubMed Mentions:
298 Fields:
Translation:
Humans
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Genetic correction of tauopathy phenotypes in neurons derived from human induced pluripotent stem cells. Stem Cell Reports. 2013; 1(3):226-34.
Fong H, Wang C, Knoferle J, Walker D, Balestra ME, Tong LM, Leung L, Ring KL, Seeley WW, Karydas A, Kshirsagar MA, Boxer AL, Kosik KS, Miller BL, Huang Y. PMID: 24319659; PMCID: PMC3849235.
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PubMed Mentions:
71 Fields:
Translation:
HumansCells
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Human von Economo neurons express transcription factors associated with Layer V subcerebral projection neurons. Cereb Cortex. 2015 Jan; 25(1):213-20.
Cobos I, Seeley WW. PMID: 23960210; PMCID: PMC4318933.
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PubMed Mentions:
30 Fields:
Translation:
HumansCells
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Rivastigmine is associated with restoration of left frontal brain activity in Parkinson's disease. Mov Disord. 2013 Sep; 28(10):1384-90.
Possin KL, Kang GA, Guo C, Fine EM, Trujillo AJ, Racine CA, Wilheim R, Johnson ET, Witt JL, Seeley WW, Miller BL, Kramer JH. PMID: 23847120; PMCID: PMC4001926.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons. Acta Neuropathol. 2013 Sep; 126(3):385-99.
Almeida S, Gascon E, Tran H, Chou HJ, Gendron TF, Degroot S, Tapper AR, Sellier C, Charlet-Berguerand N, Karydas A, Seeley WW, Boxer AL, Petrucelli L, Miller BL, Gao FB. PMID: 23836290; PMCID: PMC3753484.
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PubMed Mentions:
186 Fields:
Translation:
HumansAnimalsCells
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Intrinsic connectivity networks in healthy subjects explain clinical variability in Alzheimer's disease. Proc Natl Acad Sci U S A. 2013 Jul 09; 110(28):11606-11.
Lehmann M, Madison CM, Ghosh PM, Seeley WW, Mormino E, Greicius MD, Gorno-Tempini ML, Kramer JH, Miller BL, Jagust WJ, Rabinovici GD. PMID: 23798398; PMCID: PMC3710820.
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PubMed Mentions:
65 Fields:
Translation:
Humans
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TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease. Mol Neurodegener. 2013 Jun 21; 8:19.
Rayaprolu S, Mullen B, Baker M, Lynch T, Finger E, Seeley WW, Hatanpaa KJ, Lomen-Hoerth C, Kertesz A, Bigio EH, Lippa C, Josephs KA, Knopman DS, White CL, Caselli R, Mackenzie IR, Miller BL, Boczarska-Jedynak M, Opala G, Krygowska-Wajs A, Barcikowska M, Younkin SG, Petersen RC, Ertekin-Taner N, Uitti RJ, Meschia JF, Boylan KB, Boeve BF, Graff-Radford NR, Wszolek ZK, Dickson DW, Rademakers R, Ross OA. PMID: 23800361; PMCID: PMC3691612.
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PubMed Mentions:
202 Fields:
Translation:
Humans
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Progranulin mutations as risk factors for Alzheimer disease. JAMA Neurol. 2013 Jun; 70(6):774-8.
Perry DC, Lehmann M, Yokoyama JS, Karydas A, Lee JJ, Coppola G, Grinberg LT, Geschwind D, Seeley WW, Miller BL, Rosen H, Rabinovici G. PMID: 23609919; PMCID: PMC3743672.
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PubMed Mentions:
58 Fields:
Translation:
Humans
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Neurodegeneration, Konigsberg, and the New York City subway: dementia researchers on edge(s). Neurology. 2013 Jul 09; 81(2):104-6.
Jones DT, Seeley WW. PMID: 23719146.
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Translation:
Humans
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Heightened emotional contagion in mild cognitive impairment and Alzheimer's disease is associated with temporal lobe degeneration. Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24):9944-9.
Sturm VE, Yokoyama JS, Seeley WW, Kramer JH, Miller BL, Rankin KP. PMID: 23716653; PMCID: PMC3683715.
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PubMed Mentions:
64 Fields:
Translation:
Humans
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Mutations in protein N-arginine methyltransferases are not the cause of FTLD-FUS. Neurobiol Aging. 2013 Sep; 34(9):2235.e11-3.
Ravenscroft TA, Baker MC, Rutherford NJ, Neumann M, Mackenzie IR, Josephs KA, Boeve BF, Petersen R, Halliday GM, Kril J, van Swieten JC, Seeley WW, Dickson DW, Rademakers R. PMID: 23635657; PMCID: PMC3683824.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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The salience network causally influences default mode network activity during moral reasoning. Brain. 2013 Jun; 136(Pt 6):1929-41.
Chiong W, Wilson SM, D'Esposito M, Kayser AS, Grossman SN, Poorzand P, Seeley WW, Miller BL, Rankin KP. PMID: 23576128; PMCID: PMC3673466.
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PubMed Mentions:
103 Fields:
Translation:
Humans
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TDP-43 frontotemporal lobar degeneration and autoimmune disease. J Neurol Neurosurg Psychiatry. 2013 Sep; 84(9):956-62.
Miller ZA, Rankin KP, Graff-Radford NR, Takada LT, Sturm VE, Cleveland CM, Criswell LA, Jaeger PA, Stan T, Heggeli KA, Hsu SC, Karydas A, Khan BK, Grinberg LT, Gorno-Tempini ML, Boxer AL, Rosen HJ, Kramer JH, Coppola G, Geschwind DH, Rademakers R, Seeley WW, Wyss-Coray T, Miller BL. PMID: 23543794; PMCID: PMC3840954.
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PubMed Mentions:
78 Fields:
Translation:
Humans
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Intrinsic connectivity network disruption in progressive supranuclear palsy. Ann Neurol. 2013 May; 73(5):603-16.
Gardner RC, Boxer AL, Trujillo A, Mirsky JB, Guo CC, Gennatas ED, Heuer HW, Fine E, Zhou J, Kramer JH, Miller BL, Seeley WW. PMID: 23536287; PMCID: PMC3732833.
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PubMed Mentions:
54 Fields:
Translation:
Humans
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Structural and functional brain connectivity in presymptomatic familial frontotemporal dementia. Neurology. 2013 Feb 26; 80(9):814-23.
Dopper EG, Rombouts SA, Jiskoot LC, Heijer Td, de Graaf JR, Koning Id, Hammerschlag AR, Seelaar H, Seeley WW, Veer IM, van Buchem MA, Rizzu P, van Swieten JC. PMID: 23390180; PMCID: PMC3598452.
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PubMed Mentions:
43 Fields:
Translation:
Humans
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Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation. Acta Neuropathol. 2013 Apr; 125(4):581-93.
Grinberg LT, Wang X, Wang C, Sohn PD, Theofilas P, Sidhu M, Arevalo JB, Heinsen H, Huang EJ, Rosen H, Miller BL, Gan L, Seeley WW. PMID: 23371364; PMCID: PMC3692283.
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PubMed Mentions:
60 Fields:
Translation:
HumansCells
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Diverging patterns of amyloid deposition and hypometabolism in clinical variants of probable Alzheimer's disease. Brain. 2013 Mar; 136(Pt 3):844-58.
Lehmann M, Ghosh PM, Madison C, Laforce R, Corbetta-Rastelli C, Weiner MW, Greicius MD, Seeley WW, Gorno-Tempini ML, Rosen HJ, Miller BL, Jagust WJ, Rabinovici GD. PMID: 23358601; PMCID: PMC3580269.
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PubMed Mentions:
168 Fields:
Translation:
Humans
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Nonfluent/agrammatic PPA with in-vivo cortical amyloidosis and Pick's disease pathology. Behav Neurol. 2013; 26(1-2):95-106.
Caso F, Gesierich B, Henry M, Sidhu M, LaMarre A, Babiak M, Miller BL, Rabinovici GD, Huang EJ, Magnani G, Filippi M, Comi G, Seeley WW, Gorno-Tempini ML. PMID: 22713404; PMCID: PMC3526142.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Patterns of striatal degeneration in frontotemporal dementia. Alzheimer Dis Assoc Disord. 2013 Jan-Mar; 27(1):74-83.
Halabi C, Halabi A, Dean DL, Wang PN, Boxer AL, Trojanowski JQ, Dearmond SJ, Miller BL, Kramer JH, Seeley WW. PMID: 22367382; PMCID: PMC3389579.
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PubMed Mentions:
33 Fields:
Translation:
Humans
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Neuropsychological, behavioral, and anatomical evolution in right temporal variant frontotemporal dementia: a longitudinal and post-mortem single case analysis. Neurocase. 2014; 20(1):100-9.
Henry ML, Wilson SM, Ogar JM, Sidhu MS, Rankin KP, Cattaruzza T, Miller BL, Gorno-Tempini ML, Seeley WW. PMID: 23171151; PMCID: PMC3775867.
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PubMed Mentions:
19 Fields:
Translation:
Humans
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Introduction to the special issue on connectivity. Neuroimage. 2012 Oct 01; 62(4):2181.
Greicius MD, Seeley WW. PMID: 22902262.
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Translation:
HumansAnimals
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Frontotemporal dementia due to C9ORF72 mutations: clinical and imaging features. Neurology. 2012 Sep 04; 79(10):1002-11.
Sha SJ, Takada LT, Rankin KP, Yokoyama JS, Rutherford NJ, Fong JC, Khan B, Karydas A, Baker MC, DeJesus-Hernandez M, Pribadi M, Coppola G, Geschwind DH, Rademakers R, Lee SE, Seeley W, Miller BL, Boxer AL. PMID: 22875087; PMCID: PMC3430713.
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PubMed Mentions:
96 Fields:
Translation:
HumansCells
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Length of normal alleles of C9ORF72 GGGGCC repeat do not influence disease phenotype. Neurobiol Aging. 2012 Dec; 33(12):2950.e5-7.
Rutherford NJ, Heckman MG, Dejesus-Hernandez M, Baker MC, Soto-Ortolaza AI, Rayaprolu S, Stewart H, Finger E, Volkening K, Seeley WW, Hatanpaa KJ, Lomen-Hoerth C, Kertesz A, Bigio EH, Lippa C, Knopman DS, Kretzschmar HA, Neumann M, Caselli RJ, White CL, Mackenzie IR, Petersen RC, Strong MJ, Miller BL, Boeve BF, Uitti RJ, Boylan KB, Wszolek ZK, Graff-Radford NR, Dickson DW, Ross OA, Rademakers R. PMID: 22840558; PMCID: PMC3617405.
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PubMed Mentions:
49 Fields:
Translation:
HumansCells
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PubMed Mentions: Fields:
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Humans
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Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 2012 Jul 17; 79(3):221-8.
Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Schultz D, Rakhshan F, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N, Alzheimer's Disease Genetics Consortium (ADGC), Apostolova LG, Arnold SE, Baldwin CT, Barber R, Barmada MM, Beach T, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buros J, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Crane PK, Cruchaga C, Cummings JL, De Jager PL, DeCarli C, DeKosky ST, Demirci FY, Diaz-Arrastia R, Dick M, Dombroski BA, Duara R, Ellis WD, Evans D, Faber KM, Fallon KB, Farlow MR, Ferris S, Foroud TM, Frosch M, Galasko DR, Gallins PJ, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Goate AM, Green RC, Growdon JH, Hakonarson H, Hamilton RL, Hardy J, Harrell LE, Head E, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Kamboh MI, Karlawish J, Karydas A, Kauwe JS, Kaye JA, Kennedy N, Kim R, Koo EH, Kowall NW, Kramer P, Kukull WA, Lah JJ, Larson EB, Levey AI, Lieberman AP, Lopez OL, Lunetta KL, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Myers AJ, Naj AC, Nowotny P, Parisi JE, Perl DP, Peskind E, Poon WW, Potter H, Quinn JF, Raj A, Rajbhandary RA, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Vardarajan BN, Vinters HV, Vonsattel JP, Wang LS, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL. PMID: 22722634; PMCID: PMC3398432.
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PubMed Mentions:
87 Fields:
Translation:
Humans
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Frontotemporal dementia in eight Chinese individuals. Neurocase. 2013; 19(1):76-84.
Chao SZ, Rosen HJ, Azor V, Ong H, Tse MM, Lai NB, Hou CE, Seeley WW, Miller BL, Matthews BR. PMID: 23311888; PMCID: PMC3545415.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Gender modulates the APOE ε4 effect in healthy older adults: convergent evidence from functional brain connectivity and spinal fluid tau levels. J Neurosci. 2012 Jun 13; 32(24):8254-62.
Damoiseaux JS, Seeley WW, Zhou J, Shirer WR, Coppola G, Karydas A, Rosen HJ, Miller BL, Kramer JH, Greicius MD, Alzheimer's Disease Neuroimaging Initiative. PMID: 22699906; PMCID: PMC3394933.
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PubMed Mentions:
128 Fields:
Translation:
HumansCells
-
COMT Val158Met genotype influences neurodegeneration within dopamine-innervated brain structures. Neurology. 2012 May 22; 78(21):1663-9.
Gennatas ED, Cholfin JA, Zhou J, Crawford RK, Sasaki DA, Karydas A, Boxer AL, Bonasera SJ, Rankin KP, Gorno-Tempini ML, Rosen HJ, Kramer JH, Weiner M, Miller BL, Seeley WW. PMID: 22573634; PMCID: PMC3359506.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
ApoE and TDP-43 neuropathology in two siblings with familial FTLD-motor neuron disease. Neurocase. 2013; 19(3):295-301.
Vossel KA, Bien-Ly N, Bernardo A, Rascovsky K, Karydas A, Rabinovici GD, Sidhu M, Huang EJ, Miller BL, Huang Y, Seeley WW. PMID: 22512241; PMCID: PMC3655113.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Atypical, slowly progressive behavioural variant frontotemporal dementia associated with C9ORF72 hexanucleotide expansion. J Neurol Neurosurg Psychiatry. 2012 Apr; 83(4):358-64.
Khan BK, Yokoyama JS, Takada LT, Sha SJ, Rutherford NJ, Fong JC, Karydas AM, Wu T, Ketelle RS, Baker MC, Hernandez MD, Coppola G, Geschwind DH, Rademakers R, Lee SE, Rosen HJ, Rabinovici GD, Seeley WW, Rankin KP, Boxer AL, Miller BL. PMID: 22399793; PMCID: PMC3388906.
View in:
PubMed Mentions:
91 Fields:
Translation:
HumansCells
-
Saccade abnormalities in autopsy-confirmed frontotemporal lobar degeneration and Alzheimer disease. Arch Neurol. 2012 Apr; 69(4):509-17.
Boxer AL, Garbutt S, Seeley WW, Jafari A, Heuer HW, Mirsky J, Hellmuth J, Trojanowski JQ, Huang E, DeArmond S, Neuhaus J, Miller BL. PMID: 22491196; PMCID: PMC3423186.
View in:
PubMed Mentions:
42 Fields:
Translation:
Humans
-
Predicting regional neurodegeneration from the healthy brain functional connectome. Neuron. 2012 Mar 22; 73(6):1216-27.
Zhou J, Gennatas ED, Kramer JH, Miller BL, Seeley WW. PMID: 22445348; PMCID: PMC3361461.
View in:
PubMed Mentions:
356 Fields:
Translation:
Humans
-
One-year test-retest reliability of intrinsic connectivity network fMRI in older adults. Neuroimage. 2012 Jul 16; 61(4):1471-83.
Guo CC, Kurth F, Zhou J, Mayer EA, Eickhoff SB, Kramer JH, Seeley WW. PMID: 22446491; PMCID: PMC4226138.
View in:
PubMed Mentions:
134 Fields:
Translation:
Humans
-
Role of right pregenual anterior cingulate cortex in self-conscious emotional reactivity. Soc Cogn Affect Neurosci. 2013 Apr; 8(4):468-74.
Sturm VE, Sollberger M, Seeley WW, Rankin KP, Ascher EA, Rosen HJ, Miller BL, Levenson RW. PMID: 22345371; PMCID: PMC3624960.
View in:
PubMed Mentions:
56 Fields:
Translation:
Humans
-
Amyloid vs FDG-PET in the differential diagnosis of AD and FTLD. Neurology. 2011 Dec 06; 77(23):2034-42.
Rabinovici GD, Rosen HJ, Alkalay A, Kornak J, Furst AJ, Agarwal N, Mormino EC, O'Neil JP, Janabi M, Karydas A, Growdon ME, Jang JY, Huang EJ, Dearmond SJ, Trojanowski JQ, Grinberg LT, Gorno-Tempini ML, Seeley WW, Miller BL, Jagust WJ. PMID: 22131541; PMCID: PMC3236517.
View in:
PubMed Mentions:
140 Fields:
Translation:
Humans
-
Clinical characterization of bvFTD due to FUS neuropathology. Neurocase. 2012; 18(4):305-17.
Lee SE, Seeley WW, Poorzand P, Rademakers R, Karydas A, Stanley CM, Miller BL, Rankin KP. PMID: 22060063; PMCID: PMC3288419.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Social-emotional dysfunction after isolated right anterior insular infarction. J Neurol. 2012 Apr; 259(4):764-7.
Cho HJ, Kim SJ, Hwang SJ, Jo MK, Kim HJ, Seeley WW, Kim EJ. PMID: 21952869.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron. 2011 Oct 20; 72(2):245-56.
DeJesus-Hernandez M, Mackenzie IR, Boeve BF, Boxer AL, Baker M, Rutherford NJ, Nicholson AM, Finch NA, Flynn H, Adamson J, Kouri N, Wojtas A, Sengdy P, Hsiung GY, Karydas A, Seeley WW, Josephs KA, Coppola G, Geschwind DH, Wszolek ZK, Feldman H, Knopman DS, Petersen RC, Miller BL, Dickson DW, Boylan KB, Graff-Radford NR, Rademakers R. PMID: 21944778; PMCID: PMC3202986.
View in:
PubMed Mentions:
2281 Fields:
Translation:
HumansCells
-
Behavioral variant frontotemporal dementia with corticobasal degeneration pathology: phenotypic comparison to bvFTD with Pick's disease. J Mol Neurosci. 2011 Nov; 45(3):594-608.
Rankin KP, Mayo MC, Seeley WW, Lee S, Rabinovici G, Gorno-Tempini ML, Boxer AL, Weiner MW, Trojanowski JQ, DeArmond SJ, Miller BL. PMID: 21881831; PMCID: PMC3208125.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
Perioperative cognitive decline in the aging population. Mayo Clin Proc. 2011 Sep; 86(9):885-93.
Terrando N, Brzezinski M, Degos V, Eriksson LI, Kramer JH, Leung JM, Miller BL, Seeley WW, Vacas S, Weiner MW, Yaffe K, Young WL, Xie Z, Maze M. PMID: 21878601; PMCID: PMC3257991.
View in:
PubMed Mentions:
79 Fields:
Translation:
Humans
-
Divergent network connectivity changes in healthy APOE ε4 carriers: disinhibition or compensation? Arch Neurol. 2011 Sep; 68(9):1107-8.
Seeley WW. PMID: 21911693.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
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Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain. 2011 Sep; 134(Pt 9):2456-77.
Rascovsky K, Hodges JR, Knopman D, Mendez MF, Kramer JH, Neuhaus J, van Swieten JC, Seelaar H, Dopper EG, Onyike CU, Hillis AE, Josephs KA, Boeve BF, Kertesz A, Seeley WW, Rankin KP, Johnson JK, Gorno-Tempini ML, Rosen H, Prioleau-Latham CE, Lee A, Kipps CM, Lillo P, Piguet O, Rohrer JD, Rossor MN, Warren JD, Fox NC, Galasko D, Salmon DP, Black SE, Mesulam M, Weintraub S, Dickerson BC, Diehl-Schmid J, Pasquier F, Deramecourt V, Lebert F, Pijnenburg Y, Chow TW, Manes F, Grafman J, Cappa SF, Freedman M, Grossman M, Miller BL. PMID: 21810890; PMCID: PMC3170532.
View in:
PubMed Mentions:
1862 Fields:
Translation:
Humans
-
Clinicopathological correlations in corticobasal degeneration. Ann Neurol. 2011 Aug; 70(2):327-40.
Lee SE, Rabinovici GD, Mayo MC, Wilson SM, Seeley WW, DeArmond SJ, Huang EJ, Trojanowski JQ, Growdon ME, Jang JY, Sidhu M, See TM, Karydas AM, Gorno-Tempini ML, Boxer AL, Weiner MW, Geschwind MD, Rankin KP, Miller BL. PMID: 21823158; PMCID: PMC3154081.
View in:
PubMed Mentions:
186 Fields:
Translation:
Humans
-
Functional network disruption in the degenerative dementias. Lancet Neurol. 2011 Sep; 10(9):829-43.
Pievani M, de Haan W, Wu T, Seeley WW, Frisoni GB. PMID: 21778116; PMCID: PMC3219874.
View in:
PubMed Mentions:
212 Fields:
Translation:
Humans
-
Frontotemporal dementia: what can the behavioral variant teach us about human brain organization? Neuroscientist. 2012 Aug; 18(4):373-85.
Seeley WW, Zhou J, Kim EJ. PMID: 21670424.
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PubMed Mentions:
59 Fields:
Translation:
Humans
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Distinctive neurons of the anterior cingulate and frontoinsular cortex: a historical perspective. Cereb Cortex. 2012 Feb; 22(2):245-50.
Seeley WW, Merkle FT, Gaus SE, Craig AD, Allman JM, Hof PR, Economo CV. PMID: 21653703.
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PubMed Mentions:
57 Fields:
Translation:
HumansCells
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Selective frontoinsular von Economo neuron and fork cell loss in early behavioral variant frontotemporal dementia. Cereb Cortex. 2012 Feb; 22(2):251-9.
Kim EJ, Sidhu M, Gaus SE, Huang EJ, Hof PR, Miller BL, DeArmond SJ, Seeley WW. PMID: 21653702; PMCID: PMC3256403.
View in:
PubMed Mentions:
81 Fields:
Translation:
HumansCells
-
Ataxin-2 repeat-length variation and neurodegeneration. Hum Mol Genet. 2011 Aug 15; 20(16):3207-12.
Ross OA, Rutherford NJ, Baker M, Soto-Ortolaza AI, Carrasquillo MM, DeJesus-Hernandez M, Adamson J, Li M, Volkening K, Finger E, Seeley WW, Hatanpaa KJ, Lomen-Hoerth C, Kertesz A, Bigio EH, Lippa C, Woodruff BK, Knopman DS, White CL, Van Gerpen JA, Meschia JF, Mackenzie IR, Boylan K, Boeve BF, Miller BL, Strong MJ, Uitti RJ, Younkin SG, Graff-Radford NR, Petersen RC, Wszolek ZK, Dickson DW, Rademakers R. PMID: 21610160; PMCID: PMC3140823.
View in:
PubMed Mentions:
81 Fields:
Translation:
HumansCells
-
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet. 2011 May; 43(5):436-41.
Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JS, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FY, Baldwin CT, Green RC, Rogaeva E, St George-Hyslop P, Arnold SE, Barber R, Beach T, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Cummings JL, DeCarli C, DeKosky ST, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman AP, Lopez OL, Mack WJ, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon WW, Quinn JF, Rajbhandary RA, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosenberg RN, Sano M, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD. PMID: 21460841; PMCID: PMC3090745.
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PubMed Mentions:
1027 Fields:
Translation:
Humans
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Inclusion body myopathy with Paget disease of bone and frontotemporal dementia linked to VCP p.Arg155Cys in a Korean family. Arch Neurol. 2011 Jun; 68(6):787-96.
Kim EJ, Park YE, Kim DS, Ahn BY, Kim HS, Chang YH, Kim SJ, Kim HJ, Lee HW, Seeley WW, Kim S. PMID: 21320982.
View in:
PubMed Mentions:
21 Fields:
Translation:
Humans
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TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers. Neurology. 2011 Feb 01; 76(5):467-74.
Finch N, Carrasquillo MM, Baker M, Rutherford NJ, Coppola G, Dejesus-Hernandez M, Crook R, Hunter T, Ghidoni R, Benussi L, Crook J, Finger E, Hantanpaa KJ, Karydas AM, Sengdy P, Gonzalez J, Seeley WW, Johnson N, Beach TG, Mesulam M, Forloni G, Kertesz A, Knopman DS, Uitti R, White CL, Caselli R, Lippa C, Bigio EH, Wszolek ZK, Binetti G, Mackenzie IR, Miller BL, Boeve BF, Younkin SG, Dickson DW, Petersen RC, Graff-Radford NR, Geschwind DH, Rademakers R. PMID: 21178100; PMCID: PMC3034409.
View in:
PubMed Mentions:
141 Fields:
Translation:
Humans
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TDP-43 subtypes are associated with distinct atrophy patterns in frontotemporal dementia. Neurology. 2010 Dec 14; 75(24):2204-11.
Rohrer JD, Geser F, Zhou J, Gennatas ED, Sidhu M, Trojanowski JQ, Dearmond SJ, Miller BL, Seeley WW. PMID: 21172843; PMCID: PMC3013589.
View in:
PubMed Mentions:
87 Fields:
Translation:
HumansCells
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Network-level structural covariance in the developing brain. Proc Natl Acad Sci U S A. 2010 Oct 19; 107(42):18191-6.
Zielinski BA, Gennatas ED, Zhou J, Seeley WW. PMID: 20921389; PMCID: PMC2964249.
View in:
PubMed Mentions:
208 Fields:
Translation:
Humans
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Acetylation of tau inhibits its degradation and contributes to tauopathy. Neuron. 2010 Sep 23; 67(6):953-66.
Min SW, Cho SH, Zhou Y, Schroeder S, Haroutunian V, Seeley WW, Huang EJ, Shen Y, Masliah E, Mukherjee C, Meyers D, Cole PA, Ott M, Gan L. PMID: 20869593; PMCID: PMC3035103.
View in:
PubMed Mentions:
458 Fields:
Translation:
HumansAnimalsCells
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Clinical, neuroimaging and neuropathological features of a new chromosome 9p-linked FTD-ALS family. J Neurol Neurosurg Psychiatry. 2011 Feb; 82(2):196-203.
Boxer AL, Mackenzie IR, Boeve BF, Baker M, Seeley WW, Crook R, Feldman H, Hsiung GY, Rutherford N, Laluz V, Whitwell J, Foti D, McDade E, Molano J, Karydas A, Wojtas A, Goldman J, Mirsky J, Sengdy P, Dearmond S, Miller BL, Rademakers R. PMID: 20562461; PMCID: PMC3017222.
View in:
PubMed Mentions:
103 Fields:
Translation:
HumansCells
-
Anterior insula degeneration in frontotemporal dementia. Brain Struct Funct. 2010 Jun; 214(5-6):465-75.
Seeley WW. PMID: 20512369; PMCID: PMC2886907.
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PubMed Mentions:
72 Fields:
Translation:
Humans
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FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration. Acta Neuropathol. 2010 Jul; 120(1):33-41.
Urwin H, Josephs KA, Rohrer JD, Mackenzie IR, Neumann M, Authier A, Seelaar H, Van Swieten JC, Brown JM, Johannsen P, Nielsen JE, Holm IE, FReJA Consortium, Dickson DW, Rademakers R, Graff-Radford NR, Parisi JE, Petersen RC, Hatanpaa KJ, White CL, Weiner MF, Geser F, Van Deerlin VM, Trojanowski JQ, Miller BL, Seeley WW, van der Zee J, Kumar-Singh S, Engelborghs S, De Deyn PP, Van Broeckhoven C, Bigio EH, Deng HX, Halliday GM, Kril JJ, Munoz DG, Mann DM, Pickering-Brown SM, Doodeman V, Adamson G, Ghazi-Noori S, Fisher EM, Holton JL, Revesz T, Rossor MN, Collinge J, Mead S, Isaacs AM. PMID: 20490813; PMCID: PMC2887939.
View in:
PubMed Mentions:
108 Fields:
Translation:
Humans
-
View in:
PubMed Mentions:
475 Fields:
Translation:
Humans
-
Sporadic corticobasal syndrome due to FTLD-TDP. Acta Neuropathol. 2010 Mar; 119(3):365-74.
Tartaglia MC, Sidhu M, Laluz V, Racine C, Rabinovici GD, Creighton K, Karydas A, Rademakers R, Huang EJ, Miller BL, DeArmond SJ, Seeley WW. PMID: 19876635; PMCID: PMC2832091.
View in:
PubMed Mentions:
35 Fields:
Translation:
Humans
-
Neurodegenerative diseases target large-scale human brain networks. Neuron. 2009 Apr 16; 62(1):42-52.
Seeley WW, Crawford RK, Zhou J, Miller BL, Greicius MD. PMID: 19376066; PMCID: PMC2691647.
View in:
PubMed Mentions:
1115 Fields:
Translation:
Humans
-
Frontotemporal dementia neuroimaging: a guide for clinicians. Front Neurol Neurosci. 2009; 24:160-167.
Seeley WW. PMID: 19182474.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
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Selective functional, regional, and neuronal vulnerability in frontotemporal dementia. Curr Opin Neurol. 2008 Dec; 21(6):701-7.
Seeley WW. PMID: 18989116; PMCID: PMC2909835.
View in:
PubMed Mentions:
95 Fields:
Translation:
HumansCells
-
Frontal paralimbic network atrophy in very mild behavioral variant frontotemporal dementia. Arch Neurol. 2008 Feb; 65(2):249-55.
Seeley WW, Crawford R, Rascovsky K, Kramer JH, Weiner M, Miller BL, Gorno-Tempini ML. PMID: 18268196; PMCID: PMC2544627.
View in:
PubMed Mentions:
246 Fields:
Translation:
Humans
-
Unravelling Boléro: progressive aphasia, transmodal creativity and the right posterior neocortex. Brain. 2008 Jan; 131(Pt 1):39-49.
Seeley WW, Matthews BR, Crawford RK, Gorno-Tempini ML, Foti D, Mackenzie IR, Miller BL. PMID: 18057074.
View in:
PubMed Mentions:
53 Fields:
Translation:
Humans
-
Distinct MRI atrophy patterns in autopsy-proven Alzheimer's disease and frontotemporal lobar degeneration. Am J Alzheimers Dis Other Demen. 2007 Dec-2008 Jan; 22(6):474-88.
Rabinovici GD, Seeley WW, Kim EJ, Gorno-Tempini ML, Rascovsky K, Pagliaro TA, Allison SC, Halabi C, Kramer JH, Johnson JK, Weiner MW, Forman MS, Trojanowski JQ, Dearmond SJ, Miller BL, Rosen HJ. PMID: 18166607; PMCID: PMC2443731.
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PubMed Mentions:
116 Fields:
Translation:
Humans
-
Binge eating is associated with right orbitofrontal-insular-striatal atrophy in frontotemporal dementia. Neurology. 2007 Oct 02; 69(14):1424-33.
Woolley JD, Gorno-Tempini ML, Seeley WW, Rankin K, Lee SS, Matthews BR, Miller BL. PMID: 17909155.
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PubMed Mentions:
101 Fields:
Translation:
Humans
-
Diagnostic criteria for the behavioral variant of frontotemporal dementia (bvFTD): current limitations and future directions. Alzheimer Dis Assoc Disord. 2007 Oct-Dec; 21(4):S14-8.
Rascovsky K, Hodges JR, Kipps CM, Johnson JK, Seeley WW, Mendez MF, Knopman D, Kertesz A, Mesulam M, Salmon DP, Galasko D, Chow TW, Decarli C, Hillis A, Josephs K, Kramer JH, Weintraub S, Grossman M, Gorno-Tempini ML, Miller BM. PMID: 18090417.
View in:
PubMed Mentions:
111 Fields:
Translation:
Humans
-
Divergent social functioning in behavioral variant frontotemporal dementia and Alzheimer disease: reciprocal networks and neuronal evolution. Alzheimer Dis Assoc Disord. 2007 Oct-Dec; 21(4):S50-7.
Seeley WW, Allman JM, Carlin DA, Crawford RK, Macedo MN, Greicius MD, Dearmond SJ, Miller BL. PMID: 18090425.
View in:
PubMed Mentions:
69 Fields:
Translation:
HumansAnimalsCells
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Post-transplant acute limbic encephalitis: clinical features and relationship to HHV6. Neurology. 2007 Jul 10; 69(2):156-65.
Seeley WW, Marty FM, Holmes TM, Upchurch K, Soiffer RJ, Antin JH, Baden LR, Bromfield EB. PMID: 17620548.
View in:
PubMed Mentions:
63 Fields:
Translation:
HumansCells
-
Patterns of MRI atrophy in tau positive and ubiquitin positive frontotemporal lobar degeneration. J Neurol Neurosurg Psychiatry. 2007 Dec; 78(12):1375-8.
Kim EJ, Rabinovici GD, Seeley WW, Halabi C, Shu H, Weiner MW, DeArmond SJ, Trojanowski JQ, Gorno-Tempini ML, Miller BL, Rosen HJ. PMID: 17615169; PMCID: PMC2095621.
View in:
PubMed Mentions:
29 Fields:
Translation:
Humans
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Atrophy progression in semantic dementia with asymmetric temporal involvement: a tensor-based morphometry study. Neurobiol Aging. 2009 Jan; 30(1):103-11.
Brambati SM, Rankin KP, Narvid J, Seeley WW, Dean D, Rosen HJ, Miller BL, Ashburner J, Gorno-Tempini ML. PMID: 17604879; PMCID: PMC2643844.
View in:
PubMed Mentions:
103 Fields:
Translation:
HumansCells
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Dissociable intrinsic connectivity networks for salience processing and executive control. J Neurosci. 2007 Feb 28; 27(9):2349-56.
Seeley WW, Menon V, Schatzberg AF, Keller J, Glover GH, Kenna H, Reiss AL, Greicius MD. PMID: 17329432; PMCID: PMC2680293.
View in:
PubMed Mentions:
3266 Fields:
Translation:
Humans
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A tensor based morphometry study of longitudinal gray matter contraction in FTD. Neuroimage. 2007 Apr 15; 35(3):998-1003.
Brambati SM, Renda NC, Rankin KP, Rosen HJ, Seeley WW, Ashburner J, Weiner MW, Miller BL, Gorno-Tempini ML. PMID: 17350290; PMCID: PMC2443736.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Early frontotemporal dementia targets neurons unique to apes and humans. Ann Neurol. 2006 Dec; 60(6):660-7.
Seeley WW, Carlin DA, Allman JM, Macedo MN, Bush C, Miller BL, Dearmond SJ. PMID: 17187353.
View in:
PubMed Mentions:
126 Fields:
Translation:
HumansCells
-
View in:
PubMed Mentions:
131 Fields:
Translation:
Humans
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Frontotemporal dementia, semantic dementia, and Alzheimer's disease: the contribution of standard neuropsychological tests to differential diagnosis. J Geriatr Psychiatry Neurol. 2005 Mar; 18(1):39-44.
Diehl J, Monsch AU, Aebi C, Wagenpfeil S, Krapp S, Grimmer T, Seeley W, Förstl H, Kurz A. PMID: 15681627.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCTClinical Trials
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Neurosyphilis presenting with gummatous oculomotor nerve palsy. J Neurol Neurosurg Psychiatry. 2004 May; 75(5):789.
Seeley WW, Venna N. PMID: 15090587; PMCID: PMC1763572.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
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Ramsay Hunt syndrome associated with spinal trigeminal nucleus and tract involvement on MRI. Neurology. 2003 Nov 11; 61(9):1306-7.
Nogueira RG, Seeley WW. PMID: 14610151.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
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Benzodiazepines in schizophrenia: prefrontal cortex atrophy predicts clinical response to alprazolam augmentation. World J Biol Psychiatry. 2002 Oct; 3(4):221-4.
Seeley WW, Turetsky N, Reus VI, Wolkowitz OM. PMID: 12516314.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCTClinical Trials
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Neuroanatomy of the self: evidence from patients with frontotemporal dementia. Neurology. 2001 Sep 11; 57(5):817-21.
Miller BL, Seeley WW, Mychack P, Rosen HJ, Mena I, Boone K. PMID: 11552010.
View in:
PubMed Mentions:
42 Fields:
Translation:
Humans
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Sound-induced seizures in serotonin 5-HT2c receptor mutant mice. Nat Genet. 1997 Aug; 16(4):387-90.
Brennan TJ, Seeley WW, Kilgard M, Schreiner CE, Tecott LH. PMID: 9241279.
View in:
PubMed Mentions:
48 Fields:
Translation:
Animals